PedAM

Pediatric Disease Annotations & Medicines


	toxic megacolon

Disease ID	1750
Disease	toxic megacolon
Definition	An acute form of MEGACOLON, severe pathological dilatation of the COLON. It is associated with clinical conditions such as ULCERATIVE COLITIS; CROHN DISEASE; AMEBIC DYSENTERY; or CLOSTRIDIUM ENTEROCOLITIS.
Synonym	acute megacolon megacolon tox megacolon toxic megacolon, toxic megacolon, toxic [disease/finding] tox megacolon toxic dilatation of colon toxic megacolon (disorder)
DOID	DOID:1770
UMLS	C0025162
MeSH	D008532
SNOMED-CT	SNOMEDCT_US_2016_09_01:28536002
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:29) C0009319 \| colitis \| 13 C1257843 \| pseudomembranous colitis \| 3 C0031154 \| peritonitis \| 2 C0009324 \| ulcerative colitis \| 2 C0009492 \| compartment syndrome \| 2 C0156147 \| crohn's colitis \| 1 C0008313 \| sclerosing cholangitis \| 1 C0238067 \| collagenous colitis \| 1 C0030305 \| pancreatitis \| 1 C0566602 \| primary sclerosing cholangitis \| 1 C0004943 \| behcet's disease \| 1 C0009806 \| constipation \| 1 C0020877 \| ileitis \| 1 C0003615 \| appendicitis \| 1 C0341335 \| cmv colitis \| 1 C0001418 \| adenocarcinoma \| 1 C0011991 \| diarrhea \| 1 C0338106 \| colon adenocarcinoma \| 1 C0019061 \| haemolytic uraemic syndrome \| 1 C0162529 \| ischemic colitis \| 1 C1258215 \| ileus \| 1 C0022658 \| renal disease \| 1 C0022116 \| ischemia \| 1 C0238106 \| clostridium difficile colitis \| 1 C0021390 \| inflammatory bowel disease \| 1 C0042961 \| volvulus \| 1 C0041466 \| typhoid \| 1 C0042769 \| virus infection \| 1 C0010346 \| crohn's disease \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:23) 479 \| ATP12A \| DISEASES 1401 \| CRP \| DISEASES 4922 \| NTS \| DISEASES 3557 \| IL1RN \| DISEASES 4069 \| LYZ \| DISEASES 495 \| ATP4A \| DISEASES 6781 \| STC1 \| DISEASES 213 \| ALB \| DISEASES 117531 \| TMC1 \| DISEASES 5198 \| PFAS \| DISEASES 6863 \| TAC1 \| DISEASES 4843 \| NOS2 \| DISEASES 3363 \| HTR7 \| DISEASES 3329 \| HSPD1 \| DISEASES 5979 \| RET \| DISEASES 135250 \| RAET1E \| DISEASES 1121 \| CHM \| DISEASES 3055 \| HCK \| DISEASES 1910 \| EDNRB \| DISEASES 9467 \| SH3BP5 \| DISEASES 2319 \| FLOT2 \| DISEASES 7124 \| TNF \| DISEASES 30837 \| SOCS7 \| DISEASES
Locus	(Waiting for update.)

Disease ID	1750
Disease	toxic megacolon
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:11) HP:0002583 \| Colitis \| 8 HP:0002586 \| Peritonitis \| 2 HP:0003270 \| Distended abdomen \| 1 HP:0001733 \| Pancreatic inflammation \| 1 HP:0002595 \| Gastrointestinal atony \| 1 HP:0002580 \| Volvulus \| 1 HP:0100280 \| Morbus Crohn \| 1 HP:0002251 \| Hirschsprung megacolon \| 1 HP:0100282 \| Acute colitis \| 1 HP:0002019 \| Dyschezia \| 1 HP:0002014 \| Diarrhea \| 1

Disease ID	1750
Disease	toxic megacolon
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:1) C0011991 \| diarrhea \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:0)
(Waiting for update.)

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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