GWASdb Snp Trait(Total Genotypes:102) |
|---|
| CHR |
POS |
SNPID |
REF |
ALT |
ORI_SNPID |
PMID |
P_VALUE |
P_VALUE_TEXT |
OR/BETA |
CI95_TEXT |
GWAS_INITIAL_SAMPLE_SIZE |
SUB_POPULATION |
SUPER_POPULATION |
GWAS_TRAIT |
HPO_ID |
HPO_TERM |
DO_ID |
DO_TERM |
MESH_ID |
MESH_TERM |
EFO_ID |
EFO_TERM |
DOLITE_TERM |
RISK_ALLELE |
PUBLICATION_TYPE |
AA |
GENE_SYMBOL |
TYPE |
REFGENE |
| 1 | 201081943 | rs2281845 | C | T | rs2281845 | 21931568 | 8.00E-17 | NA | 0.1 | [0.08-0.12] unit decrease | 5,088 European ancestry women | European(5088) | ALL(5088) | EUR(5088) | ALL(5088) | Permanent tooth development | HPOID:0000696 | HPOID:0006337 | Delayed eruption of permanent teeth | Premature eruption of permanent teeth | DOID:1091 | tooth disease | NA | NA | tooth eruption | Tooth disease | rs2281845-T | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 1 | 201096383 | rs6704363 | A | G | rs6704363 | 23704328 | 3.80E-06 | NA | 0.11 | [0.06-0.16] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs6704363-A | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
| 1 | 201099275 | rs2057579 | T | C | rs2057579 | 23704328 | 2.60E-06 | NA | 0.13 | [0.08-0.19] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs2057579-T | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 2 | 109595182 | rs183780 | T | C | rs183780 | 23704328 | 6.30E-07 | NA | 0.14 | [0.08-0.19] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs183780-T | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| 2 | 217863481 | rs10932688 | C | G | rs10932688 | 23704328 | 2.90E-04 | NA | 0.11 | [0.05-0.16] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs10932688-G | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 2 | 217863481 | rs10932688 | C | G | rs10932688 | 23704328 | 3.00E-08 | NA | 0.14 | [0.092-0.194] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs10932688-G | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 2 | 217878209 | rs6435957 | T | C | rs6435957 | 20195514 | 4.00E-07 | NA | 0.37 | NA | 5,752 European ancestry related individuals | European(5752) | ALL(5752) | EUR(5752) | ALL(5752) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs6435957-T | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C | NA |
| 2 | 217878209 | rs6435957 | T | C | rs6435957 | 21931568 | 4.66E-09 | NA | NA | NA | 5,088 European ancestry women | European(5088) | ALL(5088) | EUR(5088) | ALL(5088) | Permanent tooth development | HPOID:0000696 | HPOID:0006337 | Delayed eruption of permanent teeth | Premature eruption of permanent teeth | DOID:1091 | tooth disease | NA | NA | tooth eruption | Tooth disease | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 2 | 217894756 | rs4491709 | T | C | rs4491709 | 21931568 | 2.00E-14 | NA | 0.1 | [0.07-0.13] unit decrease | 5,088 European ancestry women | European(5088) | ALL(5088) | EUR(5088) | ALL(5088) | Permanent tooth development | HPOID:0000696 | HPOID:0006337 | Delayed eruption of permanent teeth | Premature eruption of permanent teeth | DOID:1091 | tooth disease | NA | NA | tooth eruption | Tooth disease | rs4491709-T | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 2 | 217905832 | rs13387042 | A | G | rs13387042 | 21931568 | 5.49E-04 | NA | NA | NA | 5,088 European ancestry women | European(5088) | ALL(5088) | EUR(5088) | ALL(5088) | Permanent tooth development | HPOID:0000696 | HPOID:0006337 | Delayed eruption of permanent teeth | Premature eruption of permanent teeth | DOID:1091 | tooth disease | NA | NA | tooth eruption | Tooth disease | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 4 | 24375833 | rs17650401 | C | T | rs17650401 | 23918034 | 2.00E-06 | NA | 6.9 | [3.10-15.37] | 88 European ancestry cases; 580 European ancestry controls | European(668) | ALL(668) | EUR(668) | ALL(668) | Molar-incisor hypomineralization | HPOID:0000164 | Abnormality of the teeth | DOID:1091 | tooth disease | NA | NA | NA | NA | Tooth disease | rs17650401-T | Research Support, Non-U.S. Gov't | C | NA |
| 5 | 127923763 | rs11956881 | C | T | rs11956881 | 23704328 | 5.70E-07 | NA | 0.3 | [0.18-0.41] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs11956881-C | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | T |
| 6 | 106094057 | rs9386463 | A | G | rs9386463 | 20195514 | 6.00E-07 | NA | 0.38 | NA | 5,919 European ancestry related individuals | European(5919) | ALL(5919) | EUR(5919) | ALL(5919) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs9386463-G | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A | NA |
| 6 | 106188818 | rs6568401 | C | T | rs6568401 | 23704328 | 1.60E-05 | NA | 0.11 | [0.06-0.16] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs6568401-C | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 6 | 106188818 | rs6568401 | C | T | rs6568401 | 23704328 | 2.00E-10 | NA | 0.19 | [0.13-0.25] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs6568401-C | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 6 | 121098457 | rs2817937 | C | T | rs2817937 | 20195514 | 3.00E-06 | NA | 0.25 | NA | 5,752 European ancestry related individuals | European(5752) | ALL(5752) | EUR(5752) | ALL(5752) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs2817937-C | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A | NA |
| 6 | 126903011 | rs9388501 | T | C | rs9388501 | 23704328 | 5.90E-08 | NA | 0.14 | [0.09-0.2] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs9388501-C | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 7 | 19133072 | rs10225279 | G | T | rs10225279 | 23704328 | 8.50E-08 | NA | 0.15 | [0.09-0.2] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs10225279-T | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | T |
| 7 | 23517468 | rs6967145 | G | C | rs6967145 | 23704328 | 5.80E-07 | NA | 0.12 | [0.07-0.17] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs6967145-G | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
| 7 | 24018377 | rs2390854 | C | T | rs2390854 | 23704328 | 1.10E-06 | NA | 0.13 | [0.08-0.18] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs2390854-C | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 7 | 24551993 | rs11768140 | G | A | rs11768140 | 23704328 | 3.10E-06 | NA | 0.13 | [0.08-0.19] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs11768140-A | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | A,G |
| 7 | 128415195 | rs1799922 | T | G | rs1799922 | 23704328 | 4.00E-09 | NA | 0.14 | [0.097-0.191] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs1799922-T | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 7 | 128415195 | rs1799922 | T | G | rs1799922 | 23704328 | 9.00E-07 | NA | 0.14 | [0.083-0.197] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs1799922-T | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 7 | 128416561 | rs339039 | G | A | rs339039 | 23704328 | 2.20E-07 | NA | 0.16 | [0.1-0.22] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs339039-A | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | T |
| 8 | 78093837 | rs7821178 | C | A,G,T | rs7821178 | 21931568 | 9.63E-05 | NA | NA | NA | 5,088 European ancestry women | European(5088) | ALL(5088) | EUR(5088) | ALL(5088) | Permanent tooth development | HPOID:0000696 | HPOID:0006337 | Delayed eruption of permanent teeth | Premature eruption of permanent teeth | DOID:1091 | tooth disease | NA | NA | tooth eruption | Tooth disease | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 8 | 78178485 | rs6473015 | A | C | rs6473015 | 21931568 | 6.07E-06 | NA | NA | NA | 5,088 European ancestry women | European(5088) | ALL(5088) | EUR(5088) | ALL(5088) | Permanent tooth development | HPOID:0000696 | HPOID:0006337 | Delayed eruption of permanent teeth | Premature eruption of permanent teeth | DOID:1091 | tooth disease | NA | NA | tooth eruption | Tooth disease | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 8 | 81839692 | rs1445570 | G | A | rs1445570 | 23704328 | 2.60E-06 | NA | 0.11 | [0.06-0.16] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs1445570-A | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 8 | 129901910 | rs1157136 | T | C | rs1157136 | 23704328 | 6.50E-08 | NA | 0.15 | [0.1-0.21] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs1157136-T | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | T |
| 9 | 86736068 | rs2889956 | G | A | rs2889956 | 23918034 | 8.96E-06 | NA | 3.15 | [1.90-0.53] | 88 European ancestry cases; 580 European ancestry controls | European(668) | ALL(668) | EUR(668) | ALL(668) | Molar-incisor hypomineralization | HPOID:0000164 | Abnormality of the teeth | DOID:1091 | tooth disease | NA | NA | NA | NA | Tooth disease | rs2889956-A | Research Support, Non-U.S. Gov't | G | NA |
| 9 | 86741461 | rs13288553 | G | T | rs13288553 | 23918034 | 2.00E-06 | NA | 4.25 | [2.33-7.75] | 88 European ancestry cases; 580 European ancestry controls | European(668) | ALL(668) | EUR(668) | ALL(668) | Molar-incisor hypomineralization | HPOID:0000164 | Abnormality of the teeth | DOID:1091 | tooth disease | NA | NA | NA | NA | Tooth disease | rs13288553-T | Research Support, Non-U.S. Gov't | G | NA |
| 9 | 86743347 | rs7028167 | A | C | rs7028167 | 23918034 | 6.50E-06 | NA | 3.54 | [2.04-6.12] | 88 European ancestry cases; 580 European ancestry controls | European(668) | ALL(668) | EUR(668) | ALL(668) | Molar-incisor hypomineralization | HPOID:0000164 | Abnormality of the teeth | DOID:1091 | tooth disease | NA | NA | NA | NA | Tooth disease | rs7028167-C | Research Support, Non-U.S. Gov't | A | NA |
| 9 | 89074350 | rs12379293 | C | A | rs12379293 | 23704328 | 1.20E-06 | NA | 0.13 | [0.08-0.18] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs12379293-A | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 9 | 89821518 | rs451722 | G | A | rs451722 | 23704328 | 4.60E-06 | NA | 0.12 | [0.07-0.17] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs451722-G | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
| 10 | 18442482 | rs10740993 | C | T | rs10740993 | 23704328 | 2.00E-07 | NA | 0.14 | [0.088-0.194] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs10740993-C | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | T |
| 10 | 18442482 | rs10740993 | C | T | rs10740993 | 23704328 | 2.00E-09 | NA | 0.14 | [0.096-0.186] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs10740993-C | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | T |
| 10 | 76295789 | rs7924176 | A | G | rs7924176 | 21931568 | 6.00E-18 | NA | 0.11 | [0.08-0.13] unit decrease | 5,088 European ancestry women | European(5088) | ALL(5088) | EUR(5088) | ALL(5088) | Permanent tooth development | HPOID:0000696 | HPOID:0006337 | Delayed eruption of permanent teeth | Premature eruption of permanent teeth | DOID:1091 | tooth disease | NA | NA | tooth eruption | Tooth disease | rs7924176-G | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 10 | 76295789 | rs7924176 | A | G | rs7924176 | 23704328 | 2.00E-08 | NA | 0.17 | [0.11-0.22] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs7924176-A | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| 10 | 76295789 | rs7924176 | A | G | rs7924176 | 23704328 | 8.00E-16 | NA | 0.19 | [0.15-0.24] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs7924176-A | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| 10 | 76421216 | rs10824218 | A | T | rs10824218 | 23704328 | 2.00E-06 | NA | 0.13 | [0.08-0.19] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs10824218-A | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| 11 | 69664014 | rs7103884 | C | T | rs7103884 | 23704328 | 1.50E-06 | NA | 0.13 | [0.08-0.18] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs7103884-T | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 11 | 69664014 | rs7103884 | C | T | rs7103884 | 23704328 | 6.80E-08 | NA | 0.13 | [0.08-0.18] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs7103884-T | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 11 | 125826702 | rs4937076 | G | A | rs4937076 | 23704328 | 3.10E-05 | NA | 0.1 | [0.05-0.15] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs4937076-A | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| 11 | 125826702 | rs4937076 | G | A | rs4937076 | 23704328 | 4.00E-08 | NA | 0.15 | [0.097-0.203] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs4937076-A | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| 12 | 52850845 | rs421007 | G | T | rs421007 | 23704328 | 3.70E-06 | NA | 0.13 | [0.07-0.18] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs421007-G | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| 12 | 61385570 | rs11173690 | G | C | rs11173690 | 23704328 | 7.50E-06 | NA | 0.14 | [0.08-0.2] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs11173690-C | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
| 12 | 62587572 | rs10877809 | G | A | rs10877809 | 23704328 | 2.70E-06 | NA | 0.16 | [0.09-0.22] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs10877809-A | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| 12 | 63026131 | rs17732182 | C | T | rs17732182 | 23704328 | 9.00E-08 | NA | 0.18 | [0.11-0.24] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs17732182-T | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 12 | 65762058 | rs12229918 | G | C | rs12229918 | 23704328 | 2.00E-09 | NA | 0.15 | [0.1-0.198] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs12229918-C | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
| 12 | 65762058 | rs12229918 | G | C | rs12229918 | 23704328 | 7.00E-14 | NA | 0.22 | [0.16-0.27] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs12229918-C | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
| 12 | 65783378 | rs10506525 | T | C | rs10506525 | 20195514 | 6.00E-09 | NA | 0.46 | NA | 5,919 European ancestry related individuals | European(5919) | ALL(5919) | EUR(5919) | ALL(5919) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs10506525-C | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A | MSRB3 |
| 12 | 65783378 | rs10506525 | T | C | rs10506525 | 20195514 | 9.00E-07 | NA | 0.18 | NA | 5,752 European ancestry related individuals | European(5752) | ALL(5752) | EUR(5752) | ALL(5752) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs10506525-C | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A | MSRB3 |
| 12 | 66338202 | rs17101923 | G | T | rs17101923 | 23704328 | 1.00E-10 | NA | 0.18 | [0.13-0.24] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs17101923-G | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
| 12 | 66338202 | rs17101923 | G | T | rs17101923 | 23704328 | 6.00E-11 | NA | 0.21 | [0.15-0.28] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs17101923-G | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
| 12 | 66351826 | rs1351394 | T | C | rs1351394 | 21931568 | 8.19E-06 | NA | NA | NA | 5,088 European ancestry women | European(5088) | ALL(5088) | EUR(5088) | ALL(5088) | Permanent tooth development | HPOID:0000696 | HPOID:0006337 | Delayed eruption of permanent teeth | Premature eruption of permanent teeth | DOID:1091 | tooth disease | NA | NA | tooth eruption | Tooth disease | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 12 | 66364509 | rs12424086 | T | C | rs12424086 | 20195514 | 4.00E-06 | NA | 0.22 | NA | 5,752 European ancestry related individuals | European(5752) | ALL(5752) | EUR(5752) | ALL(5752) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs12424086-C | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T | NA |
| 12 | 66364509 | rs12424086 | T | C | rs12424086 | 20195514 | 8.00E-06 | NA | 0.29 | NA | 5,919 European ancestry related individuals | European(5919) | ALL(5919) | EUR(5919) | ALL(5919) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs12424086-C | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T | NA |
| 12 | 66364509 | rs12424086 | T | C | rs12424086 | 21931568 | 2.00E-12 | NA | 0.11 | [0.08-0.14] unit decrease | 5,088 European ancestry women | European(5088) | ALL(5088) | EUR(5088) | ALL(5088) | Permanent tooth development | HPOID:0000696 | HPOID:0006337 | Delayed eruption of permanent teeth | Premature eruption of permanent teeth | DOID:1091 | tooth disease | NA | NA | tooth eruption | Tooth disease | rs12424086-C | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 13 | 51390598 | rs9316505 | G | A | rs9316505 | 23704328 | 1.80E-04 | NA | 0.11 | [0.05-0.16] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs9316505-A | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| 13 | 51390598 | rs9316505 | G | A | rs9316505 | 23704328 | 3.00E-08 | NA | 0.13 | [0.086-0.18] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs9316505-A | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| 14 | 23464482 | rs997154 | G | A | rs997154 | 23704328 | 3.00E-08 | NA | 0.15 | [0.097-0.203] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs997154-G | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
| 14 | 23464482 | rs997154 | G | A | rs997154 | 23704328 | 7.00E-06 | NA | 0.14 | [0.077-0.199] unit increase | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs997154-G | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
| 14 | 37111215 | rs7146941 | A | C | rs7146941 | 23704328 | 3.70E-06 | NA | 0.11 | [0.06-0.16] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs7146941-A | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| 14 | 54417522 | rs17563 | A | G | rs17563 | 23704328 | 3.60E-04 | NA | 0.09 | [0.04-0.14] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs17563-G | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | T |
| 14 | 54417522 | rs17563 | A | G | rs17563 | 23704328 | 9.00E-17 | NA | 0.24 | [0.18-0.3] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs17563-G | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | T |
| 14 | 68728479 | rs17105278 | T | C | rs17105278 | 23704328 | 2.10E-06 | NA | 0.14 | [0.09-0.2] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs17105278-C | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | T,C |
| 14 | 68788924 | rs1956529 | C | T | rs1956529 | 20195514 | 3.00E-08 | NA | 0.51 | NA | 5,752 European ancestry related individuals | European(5752) | ALL(5752) | EUR(5752) | ALL(5752) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs1956529-T | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G | RAD51B |
| 14 | 68788924 | rs1956529 | C | T | rs1956529 | 21931568 | 3.61E-05 | NA | NA | NA | 5,088 European ancestry women | European(5088) | ALL(5088) | EUR(5088) | ALL(5088) | Permanent tooth development | HPOID:0000696 | HPOID:0006337 | Delayed eruption of permanent teeth | Premature eruption of permanent teeth | DOID:1091 | tooth disease | NA | NA | tooth eruption | Tooth disease | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 14 | 68788924 | rs1956529 | C | T | rs1956529 | 23704328 | 6.40E-07 | NA | 0.12 | [0.07-0.17] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs1956529-C | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
| 14 | 68813115 | rs1570106 | T | C | rs1570106 | 21931568 | 9.17E-04 | NA | NA | NA | 5,088 European ancestry women | European(5088) | ALL(5088) | EUR(5088) | ALL(5088) | Permanent tooth development | HPOID:0000696 | HPOID:0006337 | Delayed eruption of permanent teeth | Premature eruption of permanent teeth | DOID:1091 | tooth disease | NA | NA | tooth eruption | Tooth disease | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't |
| 16 | 54862474 | rs4131946 | T | A | rs4131946 | 23704328 | 3.10E-06 | NA | 0.12 | [0.07-0.17] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs4131946-A | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | T |
| 16 | 55078245 | rs12708948 | C | T | rs12708948 | 23704328 | 1.40E-06 | NA | 0.15 | [0.09-0.22] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs12708948-T | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 16 | 65892754 | rs1969527 | T | C | rs1969527 | 23918034 | 4.33E-06 | NA | 2.15 | [1.55-0.64] | 88 European ancestry cases; 580 European ancestry controls | European(668) | ALL(668) | EUR(668) | ALL(668) | Molar-incisor hypomineralization | HPOID:0000164 | Abnormality of the teeth | DOID:1091 | tooth disease | NA | NA | NA | NA | Tooth disease | rs1969527-C | Research Support, Non-U.S. Gov't | A | NA |
| 16 | 65895364 | rs1126179 | A | G | rs1126179 | 23918034 | 3.00E-06 | NA | 2.13 | [1.55-2.92] | 88 European ancestry cases; 580 European ancestry controls | European(668) | ALL(668) | EUR(668) | ALL(668) | Molar-incisor hypomineralization | HPOID:0000164 | Abnormality of the teeth | DOID:1091 | tooth disease | NA | NA | NA | NA | Tooth disease | rs1126179-G | Research Support, Non-U.S. Gov't | C | NA |
| 16 | 67035519 | rs11860308 | T | C | rs11860308 | 23704328 | 2.20E-06 | NA | 0.22 | [0.13-0.31] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs11860308-C | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 17 | 4839930 | rs400688 | A | G | rs400688 | 23704328 | 2.00E-06 | NA | 0.14 | [0.08-0.19] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs400688-G | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
| 17 | 7739664 | rs4130668 | T | C | rs4130668 | 23704328 | 8.60E-07 | NA | 0.13 | [0.08-0.18] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs4130668-T | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 17 | 46617019 | rs6504340 | A | G | rs6504340 | 20195514 | 6.00E-07 | NA | 0.44 | NA | 5,752 European ancestry related individuals | European(5752) | ALL(5752) | EUR(5752) | ALL(5752) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs6504340-G | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A | NA |
| 17 | 47080431 | rs1994969 | G | T | rs1994969 | 23704328 | 7.00E-16 | NA | 0.19 | [0.14-0.24] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs1994969-T | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| 17 | 47084711 | rs9674544 | G | A | rs9674544 | 20195514 | 2.00E-08 | NA | 0.27 | NA | 5,752 European ancestry related individuals | European(5752) | ALL(5752) | EUR(5752) | ALL(5752) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs9674544-G | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A | IGF2BP1 |
| 17 | 47084711 | rs9674544 | G | A | rs9674544 | 20195514 | 8.00E-07 | NA | 0.25 | NA | 5,919 European ancestry related individuals | European(5919) | ALL(5919) | EUR(5919) | ALL(5919) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs9674544-G | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A | IGF2BP1 |
| 17 | 56440542 | rs2680700 | G | T | rs2680700 | 23704328 | 5.60E-08 | NA | 0.13 | [0.08-0.18] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs2680700-T | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| 17 | 56501420 | rs2429369 | A | G | rs2429369 | 23704328 | 1.40E-07 | NA | 0.15 | [0.1-0.2] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs2429369-G | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
| 17 | 56709058 | rs412000 | G | C | rs412000 | 23704328 | 1.60E-05 | NA | 0.1 | [0.05-0.15] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs412000-C | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
| 17 | 56709058 | rs412000 | G | C | rs412000 | 23704328 | 2.00E-09 | NA | 0.16 | [0.11-0.22] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs412000-C | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
| 17 | 57229716 | rs7502947 | G | A | rs7502947 | 23704328 | 1.10E-07 | NA | 0.15 | [0.1-0.2] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs7502947-A | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| 17 | 68185586 | rs8080944 | G | A | rs8080944 | 23704328 | 2.00E-19 | NA | 0.22 | [0.17-0.27] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs8080944-A | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| 17 | 68185586 | rs8080944 | G | A | rs8080944 | 23704328 | 8.00E-34 | NA | 0.34 | [0.29-0.4] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs8080944-A | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| 17 | 68190826 | rs8079702 | G | A | rs8079702 | 20195514 | 1.00E-14 | NA | 1.15 | NA | 5,752 European ancestry related individuals | European(5752) | ALL(5752) | EUR(5752) | ALL(5752) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs8079702-G | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A | NA |
| 17 | 68190826 | rs8079702 | G | A | rs8079702 | 20195514 | 4.00E-22 | NA | 1.62 | NA | 5,919 European ancestry related individuals | European(5919) | ALL(5919) | EUR(5919) | ALL(5919) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs8079702-G | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A | NA |
| 18 | 3595011 | rs2240899 | G | C | rs2240899 | 23704328 | 2.80E-06 | NA | 0.12 | [0.07-0.17] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs2240899-C | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 19 | 52240249 | rs1993104 | C | T | rs1993104 | 23704328 | 2.80E-06 | NA | 0.15 | [0.09-0.21] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs1993104-C | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 20 | 49671435 | rs4811117 | T | G | rs4811117 | 23918034 | 5.00E-06 | NA | 3.13 | [1.92-5.13] | 88 European ancestry cases; 580 European ancestry controls | European(668) | ALL(668) | EUR(668) | ALL(668) | Molar-incisor hypomineralization | HPOID:0000164 | Abnormality of the teeth | DOID:1091 | tooth disease | NA | NA | NA | NA | Tooth disease | rs4811117-T | Research Support, Non-U.S. Gov't | G | NA |
| 20 | 49673473 | rs1123093 | A | G | rs1123093 | 23918034 | 6.58E-06 | NA | 3.5 | [2.03-0.49] | 88 European ancestry cases; 580 European ancestry controls | European(668) | ALL(668) | EUR(668) | ALL(668) | Molar-incisor hypomineralization | HPOID:0000164 | Abnormality of the teeth | DOID:1091 | tooth disease | NA | NA | NA | NA | Tooth disease | rs1123093-A | Research Support, Non-U.S. Gov't | C | NA |
| 22 | 43579049 | rs13058467 | T | C | rs13058467 | 23918034 | 4.00E-07 | NA | 4.4 | [2.50-7.80] | 88 European ancestry cases; 580 European ancestry controls | European(668) | ALL(668) | EUR(668) | ALL(668) | Molar-incisor hypomineralization | HPOID:0000164 | Abnormality of the teeth | DOID:1091 | tooth disease | NA | NA | NA | NA | Tooth disease | rs13058467-C | Research Support, Non-U.S. Gov't | C | TTLL12 |
| 22 | 43600281 | rs11703432 | T | G | rs11703432 | 23918034 | 7.51E-07 | NA | 3.8 | [2.24-0.45] | 88 European ancestry cases; 580 European ancestry controls | European(668) | ALL(668) | EUR(668) | ALL(668) | Molar-incisor hypomineralization | HPOID:0000164 | Abnormality of the teeth | DOID:1091 | tooth disease | NA | NA | NA | NA | Tooth disease | rs11703432-G | Research Support, Non-U.S. Gov't | T | SCUBE1 |
| 22 | 43605654 | rs11704836 | C | T | rs11704836 | 23918034 | 7.50E-07 | NA | 3.89 | [2.27-6.66] | 88 European ancestry cases; 580 European ancestry controls | European(668) | ALL(668) | EUR(668) | ALL(668) | Molar-incisor hypomineralization | HPOID:0000164 | Abnormality of the teeth | DOID:1091 | tooth disease | NA | NA | NA | NA | Tooth disease | rs11704836-T | Research Support, Non-U.S. Gov't | C | SCUBE1 |
| 22 | 43605770 | rs11704919 | G | A | rs11704919 | 23918034 | 8.61E-07 | NA | 3.86 | [2.25-0.44] | 88 European ancestry cases; 580 European ancestry controls | European(668) | ALL(668) | EUR(668) | ALL(668) | Molar-incisor hypomineralization | HPOID:0000164 | Abnormality of the teeth | DOID:1091 | tooth disease | NA | NA | NA | NA | Tooth disease | rs11704919-A | Research Support, Non-U.S. Gov't | G | SCUBE1 |
| 22 | 43609760 | rs2071725 | G | A | rs2071725 | 23918034 | 5.33E-06 | NA | 3.55 | [2.06-0.49] | 88 European ancestry cases; 580 European ancestry controls | European(668) | ALL(668) | EUR(668) | ALL(668) | Molar-incisor hypomineralization | HPOID:0000164 | Abnormality of the teeth | DOID:1091 | tooth disease | NA | NA | NA | NA | Tooth disease | rs2071725-A | Research Support, Non-U.S. Gov't | G | SCUBE1 |
| X | 68798703 | rs11796357 | A | G | rs11796357 | 23704328 | 3.00E-22 | NA | 0.25 | [0.2-0.3] unit decrease | 11,118 European ancestry individuals | European(11118) | ALL(11118) | EUR(11118) | ALL(11118) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs11796357-G | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| X | 68798703 | rs11796357 | A | G | rs11796357 | 23704328 | 7.00E-19 | NA | 0.2 | [0.16-0.24] unit increase | 11,513 European ancestry individuals | European(11513) | ALL(11513) | EUR(11513) | ALL(11513) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs11796357-G | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| X | 68805318 | rs4844096 | A | G | rs4844096 | 20195514 | 5.00E-11 | NA | 0.73 | NA | 5,752 European ancestry related individuals | European(5752) | ALL(5752) | EUR(5752) | ALL(5752) | Primary tooth development (number of teeth) | HPOID:0006481 | Abnormality of primary teeth | DOID:1091 | tooth disease | D000848 | Anodontia | odontogenesis | Tooth disease | rs4844096-G | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G | NA |
| X | 68892916 | rs5936487 | G | A | rs5936487 | 20195514 | 6.00E-11 | NA | 0.5 | NA | 5,919 European ancestry related individuals | European(5919) | ALL(5919) | EUR(5919) | ALL(5919) | Primary tooth development (time to first tooth eruption) | HPOID:0000680 | Delayed eruption of primary teeth | DOID:1091 | tooth disease | D003817 | Dentition | odontogenesis | Tooth disease | rs5936487-G | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G | EDA |
