PedAM

Pediatric Disease Annotations & Medicines


	tonsillitis

Disease ID	1545
Disease	tonsillitis
Definition	Inflammation of the tonsils, especially the PALATINE TONSILS but the ADENOIDS (pharyngeal tonsils) and lingual tonsils may also be involved. Tonsillitis usually is caused by bacterial infection. Tonsillitis may be acute, chronic, or recurrent.
Synonym	inflammation of tonsils inflammation tonsils throat infection - tonsillitis tonsil inflammation tonsillitides tonsillitis (disorder) tonsillitis [disease/finding] tonsillitis, nos tonsils inflammation
DOID	DOID:10456
UMLS	C0040425
MeSH	D014069
SNOMED-CT	SNOMEDCT_US_2016_09_01:90176007
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:24) C0031350 \| pharyngitis \| 2 C0024205 \| lymphadenitis \| 2 C0035021 \| recurrent fever \| 2 C0015974 \| periodic fever \| 2 C0149642 \| cervical lymphadenitis \| 2 C0033687 \| proteinuria \| 1 C0011603 \| dermatitis \| 1 C0343525 \| lemierre's syndrome \| 1 C0553662 \| juvenile rheumatoid arthritis \| 1 C0034186 \| pyelonephritis \| 1 C0018799 \| heart disease \| 1 C0021345 \| mononucleosis \| 1 C0021400 \| influenzae \| 1 C0035439 \| rheumatic heart disease \| 1 C0023467 \| acute myeloid leukemia \| 1 C0003873 \| rheumatoid arthritis \| 1 C0037199 \| sinusitis \| 1 C0023470 \| myeloid leukemia \| 1 C0017152 \| gastritis \| 1 C0031157 \| peritonsillar abscess \| 1 C0017661 \| iga nephropathy \| 1 C0011570 \| depression \| 1 C0033860 \| psoriasis \| 1 C0022658 \| nephropathy \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:154) 6376 \| CX3CL1 \| DISEASES 57595 \| PDZD4 \| DISEASES 26258 \| BLOC1S6 \| DISEASES 973 \| CD79A \| DISEASES 858 \| CAV2 \| DISEASES 56913 \| C1GALT1 \| DISEASES 727 \| C5 \| DISEASES 4353 \| MPO \| DISEASES 6357 \| CCL13 \| DISEASES 952 \| CD38 \| DISEASES 6372 \| CXCL6 \| DISEASES 3558 \| IL2 \| DISEASES 4048 \| LTA4H \| DISEASES 3458 \| IFNG \| DISEASES 57379 \| AICDA \| DISEASES 4012 \| LNPEP \| DISEASES 3565 \| IL4 \| DISEASES 3567 \| IL5 \| DISEASES 4057 \| LTF \| DISEASES 6402 \| SELL \| DISEASES 51248 \| PDZD11 \| DISEASES 10930 \| APOBEC2 \| DISEASES 718 \| C3 \| DISEASES 5199 \| CFP \| DISEASES 8139 \| GAN \| DISEASES 968 \| CD68 \| DISEASES 1401 \| CRP \| DISEASES 3569 \| IL6 \| DISEASES 56300 \| IL36G \| DISEASES 1800 \| DPEP1 \| DISEASES 9972 \| NUP153 \| DISEASES 9172 \| MYOM2 \| DISEASES 11043 \| MID2 \| DISEASES 3552 \| IL1A \| DISEASES 3553 \| IL1B \| DISEASES 3299 \| HSF4 \| DISEASES 60482 \| SLC5A7 \| DISEASES 1421 \| CRYGD \| DISEASES 2028 \| ENPEP \| DISEASES 60314 \| C12orf10 \| DISEASES 54858 \| PGPEP1 \| DISEASES 150094 \| SIK1 \| DISEASES 92235 \| DUSP27 \| DISEASES 375 \| ARF1 \| DISEASES 23549 \| DNPEP \| DISEASES 6872 \| TAF1 \| DISEASES 710 \| SERPING1 \| DISEASES 57105 \| CYSLTR2 \| DISEASES 220134 \| SKA1 \| DISEASES 10538 \| BATF \| DISEASES 219743 \| TYSND1 \| DISEASES 50848 \| F11R \| DISEASES 90525 \| SHF \| DISEASES 2220 \| FCN2 \| DISEASES 4056 \| LTC4S \| DISEASES 2215 \| FCGR3B \| DISEASES 6051 \| RNPEP \| DISEASES 213 \| ALB \| DISEASES 6374 \| CXCL5 \| DISEASES 5648 \| MASP1 \| DISEASES 51752 \| ERAP1 \| DISEASES 116842 \| LEAP2 \| DISEASES 1672 \| DEFB1 \| DISEASES 10818 \| FRS2 \| DISEASES 290 \| ANPEP \| DISEASES 1673 \| DEFB4A \| DISEASES 29071 \| C1GALT1C1 \| DISEASES 3575 \| IL7R \| DISEASES 6373 \| CXCL11 \| DISEASES 81793 \| TLR10 \| DISEASES 79834 \| PEAK1 \| DISEASES 9344 \| TAOK2 \| DISEASES 10290 \| SPEG \| DISEASES 260436 \| FDCSP \| DISEASES 4684 \| NCAM1 \| DISEASES 1068 \| CETN1 \| DISEASES 9520 \| NPEPPS \| DISEASES 414325 \| DEFB103A \| DISEASES 55 \| ACPP \| DISEASES 2 \| A2M \| DISEASES 55894 \| DEFB103B \| DISEASES 3052 \| HCCS \| DISEASES 246329 \| STAC3 \| DISEASES 926 \| CD8B \| DISEASES 348235 \| SKA2 \| DISEASES 9166 \| EBAG9 \| DISEASES 7189 \| TRAF6 \| DISEASES 23562 \| CLDN14 \| DISEASES 338599 \| DUPD1 \| DISEASES 8741 \| TNFSF13 \| DISEASES 954 \| ENTPD2 \| DISEASES 10493 \| VAT1 \| DISEASES 355 \| FAS \| DISEASES 3240 \| HP \| DISEASES 5284 \| PIGR \| DISEASES 10803 \| CCR9 \| DISEASES 5699 \| PSMB10 \| DISEASES 5116 \| PCNT \| DISEASES 1366 \| CLDN7 \| DISEASES 1803 \| DPP4 \| DISEASES 54106 \| TLR9 \| DISEASES 51660 \| MPC1 \| DISEASES 56955 \| MEPE \| DISEASES 7096 \| TLR1 \| DISEASES 2590 \| GALNT2 \| DISEASES 5664 \| PSEN2 \| DISEASES 1380 \| CR2 \| DISEASES 2328 \| FMO3 \| DISEASES 2214 \| FCGR3A \| DISEASES 962 \| CD48 \| DISEASES 922 \| CD5L \| DISEASES 6278 \| S100A7 \| DISEASES 4014 \| LOR \| DISEASES 117145 \| THEM4 \| DISEASES 5550 \| PREP \| DISEASES 8732 \| RNGTT \| DISEASES 2316 \| FLNA \| DISEASES 959 \| CD40LG \| DISEASES 51727 \| CMPK1 \| DISEASES 958 \| CD40 \| DISEASES 55315 \| SLC29A3 \| DISEASES 10800 \| CYSLTR1 \| DISEASES 6257 \| RXRB \| DISEASES 10673 \| TNFSF13B \| DISEASES 56658 \| TRIM39 \| DISEASES 160897 \| GPR180 \| DISEASES 94027 \| CGB7 \| DISEASES 444 \| ASPH \| DISEASES 51109 \| RDH11 \| DISEASES 5547 \| PRCP \| DISEASES 3886 \| KRT35 \| DISEASES 2628 \| GATM \| DISEASES 245927 \| DEFB113 \| DISEASES 10747 \| MASP2 \| DISEASES 2116 \| ETV2 \| DISEASES 28996 \| HIPK2 \| DISEASES 25777 \| SUN2 \| DISEASES 1029 \| CDKN2A \| DISEASES 7124 \| TNF \| DISEASES 4049 \| LTA \| DISEASES 94115 \| CGB8 \| DISEASES 139728 \| PNCK \| DISEASES 57862 \| ZNF410 \| DISEASES 3586 \| IL10 \| DISEASES 10046 \| MAMLD1 \| DISEASES 721 \| C4B \| DISEASES 8801 \| SUCLG2 \| DISEASES 930 \| CD19 \| DISEASES 83695 \| RHNO1 \| DISEASES 8284 \| KDM5D \| DISEASES 4850 \| CNOT4 \| DISEASES 4065 \| LY75 \| DISEASES 820 \| CAMP \| DISEASES 100128252 \| ZNF667-AS1 \| DISEASES
Locus	(Waiting for update.)

Disease ID	1545
Disease	tonsillitis
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:20) HP:0001945 \| Fever \| 8 HP:0030812 \| Tonsillar hypertrophy \| 4 HP:0002840 \| Lymphadenitis \| 2 HP:0002781 \| Upper airway obstruction \| 1 HP:0000112 \| Nephropathy \| 1 HP:0002829 \| Arthralgias \| 1 HP:0003765 \| Psoriasis \| 1 HP:0002835 \| Aspiration \| 1 HP:0012324 \| Myeloid leukemia \| 1 HP:0012393 \| Allergy \| 1 HP:0012531 \| Pain \| 1 HP:0012330 \| Pyelonephritis \| 1 HP:0005263 \| Gastritis \| 1 HP:0012595 \| Mild proteinuria \| 1 HP:0004808 \| Acute myelogenous leukemia \| 1 HP:0000093 \| Proteinuria \| 1 HP:0011109 \| Chronic sinusitis \| 1 HP:0000246 \| Sinus inflammation \| 1 HP:0011947 \| Respiratory infection \| 1 HP:0000716 \| Depression \| 1

Disease ID	1545
Disease	tonsillitis
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:2) C0015967 \| fever \| 8 C0031350 \| pharyngitis \| 2

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:3)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0040425	clozapine	D003024	5786-21-0	tonsillitis	MESH:D014069	marker/mechanism	8232685
C0040425	erythromycin	D004917	114-07-8	tonsillitis	MESH:D014069	therapeutic	12239699
C0040425	loracarbef	C054920	-	tonsillitis	MESH:D014069	therapeutic	1621750

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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