PedAM
Pediatric Disease Annotations & Medicines
| tethered cord syndrome | ||||
| Disease ID | 1705 |
|---|---|
| Disease | tethered cord syndrome |
| Definition | A progressive neurological disorder characterized by the limitation of movement of the spinal cord within the spine. It is caused by the presence of congenital or acquired tissue attachments in the spinal cord. Signs and symptoms include low back pain, scoliosis, weakness in the legs, and incontinence. |
| Synonym | congenital tethering of spinal cord cord syndrome tethered dysraphism, occult spinal dysraphisms, occult spinal occult spinal dysraphism occult spinal dysraphism sequence occult spinal dysraphism sequence (disorder) occult spinal dysraphisms spinal cord syndrome spinal dysraphism, occult spinal dysraphisms, occult tethered cord tethered cord malformation sequence tethered cord syndromes tethered spinal cord syndrome |
| DOID | |
| UMLS | C0080218 |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:5) C0023798 | lipoma | 3 C0080178 | spinal dysraphism | 3 C0007959 | charcot-marie-tooth disease | 1 C0039144 | syringomyelia | 1 C0025299 | meningocele | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:31) 479 | ATP12A | DISEASES 5184 | PEPD | DISEASES 3110 | MNX1 | DISEASES 57498 | KIDINS220 | DISEASES 26257 | NKX2-8 | DISEASES 6496 | SIX3 | DISEASES 10847 | SRCAP | DISEASES 495 | ATP4A | DISEASES 3299 | HSF4 | DISEASES 4838 | NODAL | DISEASES 43 | ACHE | DISEASES 113189 | CHST14 | DISEASES 81533 | ITFG1 | DISEASES 3855 | KRT7 | DISEASES 9573 | GDF3 | DISEASES 341947 | COX8C | DISEASES 3198 | HOXA1 | DISEASES 1896 | EDA | DISEASES 1471 | CST3 | DISEASES 79625 | NDNF | DISEASES 1645 | AKR1C1 | DISEASES 192668 | CYS1 | DISEASES 6164 | RPL34 | DISEASES 174 | AFP | DISEASES 8091 | HMGA2 | DISEASES 10989 | IMMT | DISEASES 146713 | RBFOX3 | DISEASES 2263 | FGFR2 | DISEASES 4140 | MARK3 | DISEASES 6949 | TCOF1 | DISEASES 820 | CAMP | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1705 |
|---|---|
| Disease | tethered cord syndrome |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:10) HP:0010301 | Spinal dysraphism | 3 HP:0012032 | Lipoma | 3 HP:0002475 | Myelomeningocele | 1 HP:0012033 | Sacral lipoma | 1 HP:0002385 | Paraparesis | 1 HP:0003396 | Syringomyelia | 1 HP:0002191 | Progressive spasticity | 1 HP:0010769 | Pilonidal sinus | 1 HP:0002435 | Meningocele | 1 HP:0001257 | Spasticity | 1 |
| Disease ID | 1705 |
|---|---|
| Disease | tethered cord syndrome |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:0) | |
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GWASdb Annotation(Total Genotypes:0) | |
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GWASdb Snp Trait(Total Genotypes:0) | |
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Mapped by lexical matching(Total Items:0) |
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Mapped by homologous gene(Total Items:0) |
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Chemical(Total Drugs:0) | |
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FDA approved drug and dosage information(Total Drugs:0) | |
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FDA labeling changes(Total Drugs:0) | |
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| (Waiting for update.) | |