PedAM
Pediatric Disease Annotations & Medicines
| subacute bacterial endocarditis | ||||
| Disease ID | 1284 |
|---|---|
| Disease | subacute bacterial endocarditis |
| Definition | ENDOCARDIUM infection that is usually caused by STREPTOCOCCUS. Subacute infective endocarditis evolves over weeks and months with modest toxicity and rare metastatic infection. |
| Synonym | bact endocarditides subacute bact endocarditis subacute bacterial endocarditides, subacute bacterial endocarditis (subacute) bacterial endocarditis subacute bacterial endocarditis, subacute endocarditides subacute bact endocarditides, subacute bacterial endocarditis infectious endocarditis lenta endocarditis subacute bact endocarditis, bacterial, subacute endocarditis, lenta endocarditis, subacute bacterial endocarditis, subacute bacterial [disease/finding] ie infectious endocarditis sbe sbe - subacute bacterial endocarditis subacute bact endocarditides subacute bact endocarditis subacute bacterial endocarditides subacute bacterial endocarditis (disorder) subacute endocarditis, bacterial subacute endocarditis, lenta |
| DOID | |
| UMLS | C0014122 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:5) |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:22) 10942 | PRSS21 | DISEASES 973 | CD79A | DISEASES 4353 | MPO | DISEASES 5657 | PRTN3 | DISEASES 5199 | CFP | DISEASES 1401 | CRP | DISEASES 9172 | MYOM2 | DISEASES 5443 | POMC | DISEASES 8034 | SLC25A16 | DISEASES 136991 | ASZ1 | DISEASES 5018 | OXA1L | DISEASES 6051 | RNPEP | DISEASES 10294 | DNAJA2 | DISEASES 3266 | ERAS | DISEASES 51155 | HN1 | DISEASES 28514 | DLL1 | DISEASES 3075 | CFH | DISEASES 3713 | IVL | DISEASES 959 | CD40LG | DISEASES 5799 | PTPRN2 | DISEASES 8801 | SUCLG2 | DISEASES 387715 | ARMS2 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1284 |
|---|---|
| Disease | subacute bacterial endocarditis |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:3) |
| Disease ID | 1284 |
|---|---|
| Disease | subacute bacterial endocarditis |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:1) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
All Snps(Total Genotypes:4) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs386626619 | 19735488 | 3717 | JAK2 | umls:C0014122 | BeFree | Recently several different JAK2 exon12 mutations have been identified in V617F negative polycythaemia vera (PV) or idiopathic erythrocytosis (IE) patients. | 0.000814326 | 2009 | NA | NA | NA | NA | NA |
| rs386626619 | 18528646 | 3717 | JAK2 | umls:C0014122 | BeFree | Sequence analysis was subsequently performed in the IE patient showing aberrant bands on allele-specific PCR, and a nucleotide change corresponding to the V617F mutation was detected in four of 29 clones tested. | 0.000814326 | 2008 | NA | NA | NA | NA | NA |
| rs77375493 | 18528646 | 3717 | JAK2 | umls:C0014122 | BeFree | Sequence analysis was subsequently performed in the IE patient showing aberrant bands on allele-specific PCR, and a nucleotide change corresponding to the V617F mutation was detected in four of 29 clones tested. | 0.000814326 | 2008 | JAK2;INSL6 | 9 | 5073770 | G | A,T |
| rs77375493 | 19735488 | 3717 | JAK2 | umls:C0014122 | BeFree | Recently several different JAK2 exon12 mutations have been identified in V617F negative polycythaemia vera (PV) or idiopathic erythrocytosis (IE) patients. | 0.000814326 | 2009 | JAK2;INSL6 | 9 | 5073770 | G | A,T |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
|---|
| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
|---|
| (Waiting for update.) |
Chemical(Total Drugs:2) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0014122 | ampicillin | D000667 | 69-53-4 | endocarditis, subacute bacterial | MESH:D004698 | therapeutic | 4135565 | ||
| C0014122 | vancomycin | D014640 | 1404-90-6 | endocarditis, subacute bacterial | MESH:D004698 | therapeutic | 15494887 | ||
FDA approved drug and dosage information(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |