PedAM
Pediatric Disease Annotations & Medicines
| status asthmaticus | ||||
| Disease ID | 1526 |
|---|---|
| Disease | status asthmaticus |
| Definition | A sudden intense and continuous aggravation of a state of asthma, marked by dyspnea to the point of exhaustion and collapse and not responding to the usual therapeutic efforts. |
| Synonym | (severe asthma attack) or (status asthmaticus nos) (severe asthma attack) or (status asthmaticus nos) (disorder) acute severe asthma acute severe exacerbation of asthma acute severe exacerbation of asthma (disorder) asthma asthmaticus status asthma w status asthmat asthma with status asthmaticus asthma with status asthmaticus (disorder) asthma, unspecified type, with status asthmaticus asthmatic crises asthmatic crisis asthmatic shock asthmatic shocks asthmaticus status asthmaticus, status crises, asthmatic crisis, asthmatic severe acute asthma severe asthma attack shock, asthmatic shocks, asthmatic status asthmaticus (disorder) status asthmaticus -retired- status asthmaticus [disease/finding] status asthmaticus nos status asthmaticus nos (disorder) |
| DOID | |
| UMLS | C0038218 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:6) C1145670 | respiratory failure | 4 C0024115 | pulmonary diseases | 1 C0004096 | asthma | 1 C0021400 | influenza | 1 C0878544 | cardiomyopathy | 1 C0024115 | pulmonary disease | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:43) 1361 | CPB2 | DISEASES 116449 | CLNK | DISEASES 3567 | IL5 | DISEASES 27145 | FILIP1 | DISEASES 1 | A1BG | DISEASES 1991 | ELANE | DISEASES 5775 | PTPN4 | DISEASES 5443 | POMC | DISEASES 5286 | PIK3C2A | DISEASES 7345 | UCHL1 | DISEASES 114757 | CYGB | DISEASES 6352 | CCL5 | DISEASES 5473 | PPBP | DISEASES 128 | ADH5 | DISEASES 6037 | RNASE3 | DISEASES 6869 | TACR1 | DISEASES 27289 | RND1 | DISEASES 5340 | PLG | DISEASES 1657 | DMXL1 | DISEASES 2 | A2M | DISEASES 2318 | FLNC | DISEASES 1789 | DNMT3B | DISEASES 8856 | NR1I2 | DISEASES 1908 | EDN3 | DISEASES 966 | CD59 | DISEASES 1201 | CLN3 | DISEASES 5788 | PTPRC | DISEASES 4082 | MARCKS | DISEASES 1907 | EDN2 | DISEASES 84890 | ADO | DISEASES 177 | AGER | DISEASES 3604 | TNFRSF9 | DISEASES 6354 | CCL7 | DISEASES 551 | AVP | DISEASES 55576 | STAB2 | DISEASES 4988 | OPRM1 | DISEASES 279 | AMY2A | DISEASES 56244 | BTNL2 | DISEASES 3066 | HDAC2 | DISEASES 4586 | MUC5AC | DISEASES 727897 | MUC5B | DISEASES 100124700 | HOTAIR | DISEASES 102723508 | KANTR | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1526 |
|---|---|
| Disease | status asthmaticus |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:9) HP:0002878 | Respiratory failure | 4 HP:0001941 | acidemia | 3 HP:0005972 | Respiratory acidosis | 1 HP:0012418 | Low blood oxygen level | 1 HP:0001638 | Cardiomyopathy | 1 HP:0002099 | Asthma | 1 HP:0011665 | Takotsubo cardiomyopathy | 1 HP:0001942 | Metabolic acidosis | 1 HP:0001694 | Right-to-left shunt | 1 |
| Disease ID | 1526 |
|---|---|
| Disease | status asthmaticus |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:2) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
Chemical(Total Drugs:4) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0038218 | ampicillin | D000667 | 69-53-4 | status asthmaticus | MESH:D013224 | therapeutic | 114264 | ||
| C0038218 | enflurane | D004737 | 13838-16-9 | status asthmaticus | MESH:D013224 | therapeutic | 2145134 | ||
| C0038218 | lorazepam | D008140 | 846-49-1 | status asthmaticus | MESH:D013224 | therapeutic | 7427548 | ||
| C0038218 | timolol | D013999 | 26839-75-8 | status asthmaticus | MESH:D013224 | marker/mechanism | 7219583 | ||
FDA approved drug and dosage information(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
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| (Waiting for update.) | |