PedAM
Pediatric Disease Annotations & Medicines
| spondylolysis | ||||
| Disease ID | 1518 |
|---|---|
| Disease | spondylolysis |
| Definition | Deficient development or degeneration of a portion of the VERTEBRA, usually in the pars interarticularis (the bone bridge between the superior and inferior facet joints of the LUMBAR VERTEBRAE) leading to SPONDYLOLISTHESIS. |
| Synonym | spondylolyses spondylolysis (disorder) spondylolysis [disease/finding] |
| DOID | |
| UMLS | C0038018 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:7) C0038016 | spondylolisthesis | 16 C0158266 | disc degeneration | 3 C0080178 | spina bifida | 1 C0037944 | spinal stenosis | 1 C0029408 | osteoarthritis | 1 C0038013 | ankylosing spondylitis | 1 C0036440 | idiopathic scoliosis | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:43) 10857 | PGRMC1 | DISEASES 1277 | COL1A1 | DISEASES 2521 | FUS | DISEASES 3417 | IDH1 | DISEASES 6521 | SLC4A1 | DISEASES 10558 | SPTLC1 | DISEASES 175 | AGA | DISEASES 1462 | VCAN | DISEASES 150094 | SIK1 | DISEASES 1513 | CTSK | DISEASES 2495 | FTH1 | DISEASES 23657 | SLC7A11 | DISEASES 7345 | UCHL1 | DISEASES 1836 | SLC26A2 | DISEASES 1278 | COL1A2 | DISEASES 189 | AGXT | DISEASES 10421 | CD2BP2 | DISEASES 23621 | BACE1 | DISEASES 58492 | ZNF77 | DISEASES 6863 | TAC1 | DISEASES 2811 | GP1BA | DISEASES 3418 | IDH2 | DISEASES 538 | ATP7A | DISEASES 2202 | EFEMP1 | DISEASES 1312 | COMT | DISEASES 7432 | VIP | DISEASES 914 | CD2 | DISEASES 8200 | GDF5 | DISEASES 1896 | EDA | DISEASES 3055 | HCK | DISEASES 650 | BMP2 | DISEASES 5799 | PTPRN2 | DISEASES 2524 | FUT2 | DISEASES 6152 | RPL24 | DISEASES 6164 | RPL34 | DISEASES 655 | BMP7 | DISEASES 6161 | RPL32 | DISEASES 176 | ACAN | DISEASES 6916 | TBXAS1 | DISEASES 387836 | CLEC2A | DISEASES 7086 | TKT | DISEASES 196527 | ANO6 | DISEASES 102723508 | KANTR | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1518 |
|---|---|
| Disease | spondylolysis |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:10) HP:0003302 | Spondylolithesis | 16 HP:0012531 | Pain | 3 HP:0003418 | Back pain | 2 HP:0003307 | Hyperlordosis | 1 HP:0002414 | Spina bifida | 1 HP:0002758 | Osteoarthritis | 1 HP:0008479 | Small vertebrae | 1 HP:0004626 | Lumbar scoliosis | 1 HP:0003416 | Spinal canal stenosis | 1 HP:0002944 | Thoracolumbar scoliosis | 1 |
| Disease ID | 1518 |
|---|---|
| Disease | spondylolysis |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:1) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
Chemical(Total Drugs:1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0038018 | thalidomide | D013792 | 50-35-1 | spondylolysis | MESH:D013169 | marker/mechanism | 6989723 | ||
FDA approved drug and dosage information(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |