PedAM

Pediatric Disease Annotations & Medicines


	splenic infarction

Disease ID	595
Disease	splenic infarction
Definition	Insufficiency of arterial or venous blood supply to the spleen due to emboli, thrombi, vascular torsion, or pressure that produces a macroscopic area of necrosis. (From Stedman, 25th ed)
Synonym	infarct of the spleen infarct spleen infarct, splenic infarcted spleen infarction of spleen infarction spleen infarction splenic infarction, splenic infarctions, splenic infarcts splenic infarcts, splenic spleen infarct spleen infarction splenic infarct splenic infarction (disorder) splenic infarction [disease/finding] splenic infarctions splenic infarcts
DOID	DOID:2533
ICD10	ICD10CM:D73.5
UMLS	C0037998
MeSH	D013159
SNOMED-CT	SNOMEDCT_US_2016_09_01:22996003
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:38) C0024530 \| malaria \| 5 C0037054 \| sickle cell trait \| 4 C0014118 \| endocarditis \| 4 C0014121 \| bacterial endocarditis \| 3 C0002871 \| anemia \| 2 C0014121 \| infective endocarditis \| 2 C0040053 \| thrombosis \| 2 C0002880 \| autoimmune hemolytic anemia \| 1 C0006309 \| brucellosis \| 1 C0032463 \| polycythemia vera \| 1 C0032461 \| polycythemia \| 1 C0026948 \| mycosis fungoides \| 1 C0023434 \| chronic lymphocytic leukemia \| 1 C0042769 \| viral infections \| 1 C0235974 \| pancreatic cancer \| 1 C0032302 \| mycoplasma pneumonia \| 1 C0024537 \| vivax malaria \| 1 C0032285 \| pneumoniae \| 1 C0004153 \| atherosclerosis \| 1 C0012739 \| consumptive coagulopathy \| 1 C0002895 \| sickle cell disease \| 1 C0024623 \| gastric cancer \| 1 C0021345 \| mononucleosis \| 1 C0042769 \| virus infection \| 1 C0031154 \| peritonitis \| 1 C0009324 \| ulcerative colitis \| 1 C0398625 \| protein c deficiency \| 1 C0042769 \| viral infection \| 1 C0036472 \| scrub typhus \| 1 C0010631 \| cystadenocarcinoma \| 1 C0002878 \| hemolytic anemia \| 1 C0026946 \| mycosis \| 1 C0206699 \| mucinous cystadenocarcinoma \| 1 C0021345 \| infectious mononucleosis \| 1 C0002895 \| sickle cell anemia \| 1 C0026934 \| mycoplasma \| 1 C0085278 \| antiphospholipid syndrome \| 1 C0032827 \| k deficiency \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:36) 1357 \| CPA1 \| DISEASES 6793 \| STK10 \| DISEASES 27344 \| PCSK1N \| DISEASES 6783 \| SULT1E1 \| DISEASES 2735 \| GLI1 \| DISEASES 1401 \| CRP \| DISEASES 5286 \| PIK3C2A \| DISEASES 939 \| CD27 \| DISEASES 6326 \| SCN2A \| DISEASES 252969 \| NEIL2 \| DISEASES 114757 \| CYGB \| DISEASES 5473 \| PPBP \| DISEASES 6690 \| SPINK1 \| DISEASES 6447 \| SCG5 \| DISEASES 9780 \| PIEZO1 \| DISEASES 2147 \| F2 \| DISEASES 5644 \| PRSS1 \| DISEASES 5340 \| PLG \| DISEASES 6868 \| ADAM17 \| DISEASES 3043 \| HBB \| DISEASES 2152 \| F3 \| DISEASES 3266 \| ERAS \| DISEASES 921 \| CD5 \| DISEASES 6288 \| SAA1 \| DISEASES 6693 \| SPN \| DISEASES 84072 \| HORMAD1 \| DISEASES 462 \| SERPINC1 \| DISEASES 1369 \| CPN1 \| DISEASES 959 \| CD40LG \| DISEASES 8200 \| GDF5 \| DISEASES 11330 \| CTRC \| DISEASES 4524 \| MTHFR \| DISEASES 116511 \| MAS1L \| DISEASES 26278 \| SACS \| DISEASES 12 \| SERPINA3 \| DISEASES 279 \| AMY2A \| DISEASES
Locus	(Waiting for update.)

Disease ID	595
Disease	splenic infarction
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:23) HP:0006689 \| Bacterial endocarditis \| 5 HP:0100584 \| Endocarditis \| 4 HP:0001744 \| Splenomegaly \| 3 HP:0001903 \| Anemia \| 2 HP:0001433 \| Enlarged liver and spleen \| 2 HP:0012531 \| Pain \| 2 HP:0100279 \| Ulcerative colitis \| 1 HP:0100806 \| Sepsis \| 1 HP:0012126 \| Gastric cancer \| 1 HP:0005550 \| Chronic lymphatic leukemia \| 1 HP:0002586 \| Peritonitis \| 1 HP:0001748 \| Polysplenia \| 1 HP:0005543 \| Reduced protein C activity \| 1 HP:0000790 \| Hematuria \| 1 HP:0002027 \| Abdominal pain \| 1 HP:0001901 \| Abnormally shaped erythrocytes \| 1 HP:0004936 \| Blood clot in vein \| 1 HP:0001880 \| Eosinophilia \| 1 HP:0011854 \| Hemoperitoneum \| 1 HP:0001746 \| Absent spleen \| 1 HP:0001890 \| Autoimmune hemolytic anemia \| 1 HP:0002621 \| Atherosclerosis \| 1 HP:0001878 \| Haemolytic anaemia \| 1

Disease ID	595
Disease	splenic infarction
Manually Symptom	UMLS \| Name(Total Manually Symptoms:7) C0740577 \| acute abdominal pain C0684239 \| tenderness C0403379 \| emphysematous pyelonephritis C0198632 \| pneumoperitoneum C0040028 \| essential thrombocythemia C0034362 \| q-fever C0000737 \| abdominal pain
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:1) C0000737 \| abdominal pain \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:3)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0037998	clofazimine	D002991	2030-63-9	splenic infarction	MESH:D013159	marker/mechanism	7387877
C0037998	desogestrel	D017135	54024-22-5	splenic infarction	MESH:D013159	marker/mechanism	9553191
C0037998	tretinoin	D014212	302-79-4	splenic infarction	MESH:D013159	marker/mechanism	12952241

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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