PedAM

Pediatric Disease Annotations & Medicines


	spinal cord disease

Disease ID	1556
Disease	spinal cord disease
Definition	Pathologic conditions which feature SPINAL CORD damage or dysfunction, including disorders involving the meninges and perimeningeal spaces surrounding the spinal cord. Traumatic injuries, vascular diseases, infections, and inflammatory/autoimmune processes may affect the spinal cord.
Synonym	disease of spinal cord disease of spinal cord, nos mp - myelopathy myelopathies myelopathy (disorder) myelopathy due to disease nos myelopathy due to disease nos (disorder) myelopathy nos myelopathy nos (disorder) myelopathy, nos neurologic myelopathy neurologic myelopathy, nos neurologic myelopathy-retired neurologic myelopathy-retired (disorder) spinal cord dis spinal cord disease nos spinal cord diseases spinal cord diseases [disease/finding] spinal cord disorder spinal cord disorder (disorder) spinal cord disorders spinal cord--diseases unspecified disease of spinal cord
DOID	DOID:319
UMLS	C0037928
MeSH	D013118
SNOMED-CT	SNOMEDCT_US_2016_09_01:48522003
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:3) C0009806 \| constipation \| 1 C2004461 \| bowel dysfunction \| 1 C0009806 \| constipated \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:3) ADA \| 100 \| CTD_human APP \| 351 \| CTD_human MTHFR \| 4524 \| CTD_human
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:307) 920 \| CD4 \| DISEASES 1634 \| DCN \| DISEASES 90956 \| ADCK2 \| DISEASES 9741 \| LAPTM4A \| DISEASES 27248 \| ERLEC1 \| DISEASES 350 \| APOH \| DISEASES 2999 \| GZMH \| DISEASES 3002 \| GZMB \| DISEASES 10857 \| PGRMC1 \| DISEASES 215 \| ABCD1 \| DISEASES 10084 \| PQBP1 \| DISEASES 4313 \| MMP2 \| DISEASES 9333 \| TGM5 \| DISEASES 8797 \| TNFRSF10A \| DISEASES 973 \| CD79A \| DISEASES 7087 \| ICAM5 \| DISEASES 1406 \| CRX \| DISEASES 727 \| C5 \| DISEASES 6348 \| CCL3 \| DISEASES 6347 \| CCL2 \| DISEASES 3558 \| IL2 \| DISEASES 969 \| CD69 \| DISEASES 3458 \| IFNG \| DISEASES 2026 \| ENO2 \| DISEASES 3565 \| IL4 \| DISEASES 51185 \| CRBN \| DISEASES 11126 \| CD160 \| DISEASES 6402 \| SELL \| DISEASES 9519 \| TBPL1 \| DISEASES 23435 \| TARDBP \| DISEASES 3425 \| IDUA \| DISEASES 968 \| CD68 \| DISEASES 83483 \| PLVAP \| DISEASES 3050 \| HBZ \| DISEASES 3110 \| MNX1 \| DISEASES 2670 \| GFAP \| DISEASES 2521 \| FUS \| DISEASES 6737 \| TRIM21 \| DISEASES 10462 \| CLEC10A \| DISEASES 5375 \| PMP2 \| DISEASES 57498 \| KIDINS220 \| DISEASES 2694 \| GIF \| DISEASES 3431 \| SP110 \| DISEASES 1144 \| CHRND \| DISEASES 3569 \| IL6 \| DISEASES 26257 \| NKX2-8 \| DISEASES 11258 \| DCTN3 \| DISEASES 26160 \| IFT172 \| DISEASES 3417 \| IDH1 \| DISEASES 4001 \| LMNB1 \| DISEASES 59341 \| TRPV4 \| DISEASES 16 \| AARS \| DISEASES 23531 \| MMD \| DISEASES 9480 \| ONECUT2 \| DISEASES 9172 \| MYOM2 \| DISEASES 10847 \| SRCAP \| DISEASES 6132 \| RPL8 \| DISEASES 25939 \| SAMHD1 \| DISEASES 3552 \| IL1A \| DISEASES 3553 \| IL1B \| DISEASES 4854 \| NOTCH3 \| DISEASES 25978 \| CHMP2B \| DISEASES 23095 \| KIF1B \| DISEASES 3931 \| LCAT \| DISEASES 3299 \| HSF4 \| DISEASES 2208 \| FCER2 \| DISEASES 941 \| CD80 \| DISEASES 2247 \| FGF2 \| DISEASES 10723 \| SLC12A7 \| DISEASES 55573 \| CDV3 \| DISEASES 6507 \| SLC1A3 \| DISEASES 8829 \| NRP1 \| DISEASES 25996 \| REXO2 \| DISEASES 23761 \| PISD \| DISEASES 939 \| CD27 \| DISEASES 3073 \| HEXA \| DISEASES 2588 \| GALNS \| DISEASES 7157 \| TP53 \| DISEASES 6647 \| SOD1 \| DISEASES 52 \| ACP1 \| DISEASES 3001 \| GZMA \| DISEASES 5921 \| RASA1 \| DISEASES 3578 \| IL9 \| DISEASES 4594 \| MUT \| DISEASES 340419 \| RSPO2 \| DISEASES 3439 \| IFNA1 \| DISEASES 23196 \| FAM120A \| DISEASES 6506 \| SLC1A2 \| DISEASES 472 \| ATM \| DISEASES 10205 \| MPZL2 \| DISEASES 114571 \| SLC22A9 \| DISEASES 51594 \| NBAS \| DISEASES 2895 \| GRID2 \| DISEASES 5903 \| RANBP2 \| DISEASES 925 \| CD8A \| DISEASES 56172 \| ANKH \| DISEASES 116337 \| PANX3 \| DISEASES 7345 \| UCHL1 \| DISEASES 9510 \| ADAMTS1 \| DISEASES 5922 \| RASA2 \| DISEASES 10563 \| CXCL13 \| DISEASES 392255 \| GDF6 \| DISEASES 4838 \| NODAL \| DISEASES 197258 \| FUK \| DISEASES 56896 \| DPYSL5 \| DISEASES 55114 \| ARHGAP17 \| DISEASES 6285 \| S100B \| DISEASES 1234 \| CCR5 \| DISEASES 6352 \| CCL5 \| DISEASES 10197 \| PSME3 \| DISEASES 362 \| AQP5 \| DISEASES 178 \| AGL \| DISEASES 7412 \| VCAM1 \| DISEASES 213 \| ALB \| DISEASES 5364 \| PLXNB1 \| DISEASES 84315 \| MON1A \| DISEASES 4486 \| MST1R \| DISEASES 3600 \| IL15 \| DISEASES 9607 \| CARTPT \| DISEASES 1437 \| CSF2 \| DISEASES 114801 \| TMEM200A \| DISEASES 1152 \| CKB \| DISEASES 201161 \| CENPV \| DISEASES 23582 \| CCNDBP1 \| DISEASES 4909 \| NTF4 \| DISEASES 284110 \| GSDMA \| DISEASES 55867 \| SLC22A11 \| DISEASES 6356 \| CCL11 \| DISEASES 3688 \| ITGB1 \| DISEASES 1140 \| CHRNB1 \| DISEASES 171558 \| PTCRA \| DISEASES 1495 \| CTNNA1 \| DISEASES 3627 \| CXCL10 \| DISEASES 56246 \| MRAP \| DISEASES 114990 \| VASN \| DISEASES 1473 \| CST5 \| DISEASES 5002 \| SLC22A18 \| DISEASES 695 \| BTK \| DISEASES 1808 \| DPYSL2 \| DISEASES 947 \| CD34 \| DISEASES 358 \| AQP1 \| DISEASES 84868 \| HAVCR2 \| DISEASES 64236 \| PDLIM2 \| DISEASES 66037 \| BOLL \| DISEASES 55084 \| SOBP \| DISEASES 81533 \| ITFG1 \| DISEASES 80153 \| EDC3 \| DISEASES 6863 \| TAC1 \| DISEASES 4222 \| MEOX1 \| DISEASES 923 \| CD6 \| DISEASES 26230 \| TIAM2 \| DISEASES 8784 \| TNFRSF18 \| DISEASES 6900 \| CNTN2 \| DISEASES 54584 \| GNB1L \| DISEASES 9573 \| GDF3 \| DISEASES 3418 \| IDH2 \| DISEASES 942 \| CD86 \| DISEASES 90249 \| UNC5A \| DISEASES 3916 \| LAMP1 \| DISEASES 9112 \| MTA1 \| DISEASES 5133 \| PDCD1 \| DISEASES 80011 \| FAM192A \| DISEASES 30850 \| CDR2L \| DISEASES 57142 \| RTN4 \| DISEASES 554 \| AVPR2 \| DISEASES 7704 \| ZBTB16 \| DISEASES 6809 \| STX3 \| DISEASES 23583 \| SMUG1 \| DISEASES 222236 \| NAPEPLD \| DISEASES 341947 \| COX8C \| DISEASES 3178 \| HNRNPA1 \| DISEASES 3198 \| HOXA1 \| DISEASES 4077 \| NBR1 \| DISEASES 3344 \| FOXN2 \| DISEASES 3605 \| IL17A \| DISEASES 92737 \| DNER \| DISEASES 57556 \| SEMA6A \| DISEASES 3767 \| KCNJ11 \| DISEASES 3181 \| HNRNPA2B1 \| DISEASES 23481 \| PES1 \| DISEASES 8650 \| NUMB \| DISEASES 26503 \| SLC17A5 \| DISEASES 273 \| AMPH \| DISEASES 10507 \| SEMA4D \| DISEASES 1778 \| DYNC1H1 \| DISEASES 23299 \| BICD2 \| DISEASES 1996 \| ELAVL4 \| DISEASES 871 \| SERPINH1 \| DISEASES 4763 \| NF1 \| DISEASES 617 \| BCS1L \| DISEASES 23607 \| CD2AP \| DISEASES 3123 \| HLA-DRB1 \| DISEASES 3164 \| NR4A1 \| DISEASES 11169 \| WDHD1 \| DISEASES 4283 \| CXCL9 \| DISEASES 51603 \| METTL13 \| DISEASES 1291 \| COL6A1 \| DISEASES 9851 \| KIAA0753 \| DISEASES 4548 \| MTR \| DISEASES 2853 \| GPR31 \| DISEASES 6993 \| DYNLT1 \| DISEASES 84946 \| LTV1 \| DISEASES 356 \| FASLG \| DISEASES 55811 \| ADCY10 \| DISEASES 1892 \| ECHS1 \| DISEASES 3713 \| IVL \| DISEASES 50624 \| CUZD1 \| DISEASES 914 \| CD2 \| DISEASES 965 \| CD58 \| DISEASES 959 \| CD40LG \| DISEASES 26036 \| ZNF451 \| DISEASES 51013 \| EXOSC1 \| DISEASES 5236 \| PGM1 \| DISEASES 11253 \| MAN1B1 \| DISEASES 29991 \| OBP2A \| DISEASES 57109 \| REXO4 \| DISEASES 4318 \| MMP9 \| DISEASES 64834 \| ELOVL1 \| DISEASES 5292 \| PIM1 \| DISEASES 2833 \| CXCR3 \| DISEASES 7321 \| UBE2D1 \| DISEASES 1896 \| EDA \| DISEASES 3339 \| HSPG2 \| DISEASES 1302 \| COL11A2 \| DISEASES 4758 \| NEU1 \| DISEASES 10673 \| TNFSF13B \| DISEASES 50943 \| FOXP3 \| DISEASES 7133 \| TNFRSF1B \| DISEASES 1041 \| CDSN \| DISEASES 4524 \| MTHFR \| DISEASES 4340 \| MOG \| DISEASES 1471 \| CST3 \| DISEASES 81562 \| LMAN2L \| DISEASES 22883 \| CLSTN1 \| DISEASES 2131 \| EXT1 \| DISEASES 650 \| BMP2 \| DISEASES 3801 \| KIFC3 \| DISEASES 203228 \| C9orf72 \| DISEASES 3456 \| IFNB1 \| DISEASES 1280 \| COL2A1 \| DISEASES 6606 \| SMN1 \| DISEASES 6607 \| SMN2 \| DISEASES 347527 \| ARSH \| DISEASES 51378 \| ANGPT4 \| DISEASES 26278 \| SACS \| DISEASES 4155 \| MBP \| DISEASES 2235 \| FECH \| DISEASES 361 \| AQP4 \| DISEASES 201633 \| TIGIT \| DISEASES 55576 \| STAB2 \| DISEASES 3681 \| ITGAD \| DISEASES 2617 \| GARS \| DISEASES 11202 \| KLK8 \| DISEASES 9244 \| CRLF1 \| DISEASES 2591 \| GALNT3 \| DISEASES 78996 \| C7orf49 \| DISEASES 6164 \| RPL34 \| DISEASES 6696 \| SPP1 \| DISEASES 79924 \| ADM2 \| DISEASES 2737 \| GLI3 \| DISEASES 8887 \| TAX1BP1 \| DISEASES 2868 \| GRK4 \| DISEASES 8091 \| HMGA2 \| DISEASES 95 \| ACY1 \| DISEASES 7514 \| XPO1 \| DISEASES 57703 \| CWC22 \| DISEASES 176 \| ACAN \| DISEASES 1385 \| CREB1 \| DISEASES 2086 \| ERV3-1 \| DISEASES 3800 \| KIF5C \| DISEASES 197 \| AHSG \| DISEASES 85443 \| DCLK3 \| DISEASES 5783 \| PTPN13 \| DISEASES 7124 \| TNF \| DISEASES 7072 \| TIA1 \| DISEASES 5817 \| PVR \| DISEASES 4049 \| LTA \| DISEASES 54900 \| LAX1 \| DISEASES 3115 \| HLA-DPB1 \| DISEASES 2668 \| GDNF \| DISEASES 30836 \| DNTTIP2 \| DISEASES 3586 \| IL10 \| DISEASES 627 \| BDNF \| DISEASES 133396 \| IL31RA \| DISEASES 339487 \| ZBTB8OS \| DISEASES 1496 \| CTNNA2 \| DISEASES 400916 \| CHCHD10 \| DISEASES 4700 \| NDUFA6 \| DISEASES 135935 \| NOBOX \| DISEASES 30816 \| ERVW-1 \| DISEASES 5542 \| PRB1 \| DISEASES 6949 \| TCOF1 \| DISEASES 51428 \| DDX41 \| DISEASES 137994 \| LETM2 \| DISEASES 10687 \| PNMA2 \| DISEASES 3347 \| HTN3 \| DISEASES 84107 \| ZIC4 \| DISEASES 930 \| CD19 \| DISEASES 83857 \| TMTC1 \| DISEASES 387882 \| C12orf75 \| DISEASES 567 \| B2M \| DISEASES 23186 \| RCOR1 \| DISEASES 4782 \| NFIC \| DISEASES 246734 \| NPCDR1 \| DISEASES 554203 \| JPX \| DISEASES 102723508 \| KANTR \| DISEASES 4574 \| MT-TS1 \| DISEASES
Locus	(Waiting for update.)

Disease ID	1556
Disease	spinal cord disease
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:2) HP:0002459 \| Dysautonomia \| 1 HP:0002019 \| Dyschezia \| 1

Disease ID	1556
Disease	spinal cord disease
Manually Symptom	(Waiting for update.)
Text Mined Symptom	(Waiting for update.)

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:21)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0037928	s-adenosylmethionine	D012436	29908-03-0	spinal cord diseases	MESH:D013118	therapeutic	19821069
C0037928	betamethasone	D001623	378-44-9	spinal cord diseases	MESH:D013118	marker/mechanism	19863744
C0037928	bupivacaine	D002045	2180-92-9	spinal cord diseases	MESH:D013118	marker/mechanism	15082141
C0037928	carmustine	D002330	154-93-8	spinal cord diseases	MESH:D013118	marker/mechanism	11020424
C0037928	clonidine	D003000	4205-90-7	spinal cord diseases	MESH:D013118	marker/mechanism	15082141
C0037928	cyclophosphamide	D003520	50-18-0	spinal cord diseases	MESH:D013118	therapeutic	9404148
C0037928	cisplatin	D002945	15663-27-1	spinal cord diseases	MESH:D013118	marker/mechanism	11020424
C0037928	droperidol	D004329	548-73-2	spinal cord diseases	MESH:D013118	marker/mechanism	3674497
C0037928	folic acid	D005492	59-30-3	spinal cord diseases	MESH:D013118	marker/mechanism	7527320
C0037928	folic acid	D005492	59-30-3	spinal cord diseases	MESH:D013118	therapeutic	16361298
C0037928	leucovorin	D002955	1958/5/9	spinal cord diseases	MESH:D013118	therapeutic	19821069
C0037928	lidocaine	D008012	137-58-6	spinal cord diseases	MESH:D013118	marker/mechanism	171983
C0037928	methadone	D008691	76-99-3	spinal cord diseases	MESH:D013118	marker/mechanism	4586767
C0037928	methotrexate	D008727	1959/5/2	spinal cord diseases	MESH:D013118	marker/mechanism	11800653
C0037928	morphine	D009020	57-27-2	spinal cord diseases	MESH:D013118	marker/mechanism	8087444
C0037928	nitric oxide	D009569	10102-43-9	spinal cord diseases	MESH:D013118	marker/mechanism	16325979
C0037928	paclitaxel	D017239	-	spinal cord diseases	MESH:D013118	marker/mechanism	11022860
C0037928	ropivacaine	C037663	84057-95-4	spinal cord diseases	MESH:D013118	marker/mechanism	20014599
C0037928	valproic acid	D014635	99-66-1	spinal cord diseases	MESH:D013118	marker/mechanism	11698905
C0037928	vinorelbine	C030852	71486-22-1	spinal cord diseases	MESH:D013118	marker/mechanism	11778975
C0037928	zidovudine	D015215	30516-87-1	spinal cord diseases	MESH:D013118	marker/mechanism	2899263

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)