PedAM

Pediatric Disease Annotations & Medicines


	somatoform disorder

Disease ID	1286
Disease	somatoform disorder
Definition	Disorders having the presence of physical symptoms that suggest a general medical condition but that are not fully explained by another medical condition, by the direct effects of a substance, or by another mental disorder. The MEDICALLY UNEXPLAINED SYMPTOMS must cause clinically significant distress or impairment in social, occupational, or other areas of functioning. In contrast to FACTITIOUS DISORDERS and MALINGERING, the physical symptoms are not under voluntary control. (APA, DSM-V)
Synonym	[x]somatoform disorder, unspecified [x]somatoform disorder, unspecified (disorder) disorder somatoform disorder, somatoform disorders, somatoform medically unexplained syndrome medically unexplained syndromes psychogenic disorder psychogenic disorders psychogenic syndrome psychogenic syndromes nos psychogenic syndromes nos (disorder) somatoform dis somatoform disorder (disorder) somatoform disorder nos somatoform disorder, nos somatoform disorders somatoform disorders [disease/finding] syndrome, medically unexplained syndromes, medically unexplained unexplained syndrome, medically unexplained syndromes, medically
DOID	DOID:4737
UMLS	C0037650
MeSH	D013001
SNOMED-CT	SNOMEDCT_US_2016_09_01:31297008
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:13) C0003467 \| anxiety \| 7 C0011570 \| depression \| 6 C0003469 \| anxiety disorder \| 2 C0003469 \| anxiety disorders \| 2 C0013415 \| dysthymia \| 1 C0004936 \| mental disorders \| 1 C0041696 \| major depression \| 1 C0520482 \| somatization disorder \| 1 C0005586 \| bipolar disorder \| 1 C0020604 \| hypochondriasis \| 1 C0030567 \| parkinson's disease \| 1 C0002020 \| alexithymia \| 1 C0030567 \| parkinson disease \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:1) IFNA2 \| 3440 \| CTD_human
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:244) 100126791 \| EGOT \| DISEASES 22846 \| VASH1 \| DISEASES 9741 \| LAPTM4A \| DISEASES 7380 \| UPK3A \| DISEASES 64841 \| GNPNAT1 \| DISEASES 5173 \| PDYN \| DISEASES 5020 \| OXT \| DISEASES 479 \| ATP12A \| DISEASES 58189 \| WFDC1 \| DISEASES 4210 \| MEFV \| DISEASES 7392 \| USF2 \| DISEASES 51200 \| CPA4 \| DISEASES 11101 \| ATE1 \| DISEASES 6348 \| CCL3 \| DISEASES 5023 \| P2RX1 \| DISEASES 6347 \| CCL2 \| DISEASES 2784 \| GNB3 \| DISEASES 9450 \| LY86 \| DISEASES 10279 \| PRSS16 \| DISEASES 2690 \| GHR \| DISEASES 1839 \| HBEGF \| DISEASES 3565 \| IL4 \| DISEASES 80306 \| MED28 \| DISEASES 103910 \| MYL12B \| DISEASES 3070 \| HELLS \| DISEASES 8600 \| TNFSF11 \| DISEASES 9496 \| TBX4 \| DISEASES 2693 \| GHSR \| DISEASES 4852 \| NPY \| DISEASES 11034 \| DSTN \| DISEASES 92797 \| HELB \| DISEASES 7166 \| TPH1 \| DISEASES 1215 \| CMA1 \| DISEASES 15 \| AANAT \| DISEASES 8220 \| DGCR14 \| DISEASES 9997 \| SCO2 \| DISEASES 2670 \| GFAP \| DISEASES 10267 \| RAMP1 \| DISEASES 51540 \| SCLY \| DISEASES 23135 \| KDM6B \| DISEASES 182 \| JAG1 \| DISEASES 1401 \| CRP \| DISEASES 4922 \| NTS \| DISEASES 7024 \| TFCP2 \| DISEASES 3569 \| IL6 \| DISEASES 2615 \| LRRC32 \| DISEASES 9360 \| PPIG \| DISEASES 64398 \| MPP5 \| DISEASES 6532 \| SLC6A4 \| DISEASES 8989 \| TRPA1 \| DISEASES 495 \| ATP4A \| DISEASES 25939 \| SAMHD1 \| DISEASES 23523 \| CABIN1 \| DISEASES 2033 \| EP300 \| DISEASES 5024 \| P2RX3 \| DISEASES 3553 \| IL1B \| DISEASES 9424 \| KCNK6 \| DISEASES 7379 \| UPK2 \| DISEASES 2817 \| GPC1 \| DISEASES 7348 \| UPK1B \| DISEASES 5443 \| POMC \| DISEASES 80321 \| CEP70 \| DISEASES 3827 \| KNG1 \| DISEASES 286 \| ANK1 \| DISEASES 55749 \| CCAR1 \| DISEASES 5286 \| PIK3C2A \| DISEASES 57332 \| CBX8 \| DISEASES 150094 \| SIK1 \| DISEASES 3358 \| HTR2C \| DISEASES 1392 \| CRH \| DISEASES 55327 \| LIN7C \| DISEASES 51348 \| KLRF1 \| DISEASES 2904 \| GRIN2B \| DISEASES 8562 \| DENR \| DISEASES 7082 \| TJP1 \| DISEASES 2911 \| GRM1 \| DISEASES 3192 \| HNRNPU \| DISEASES 3773 \| KCNJ16 \| DISEASES 7345 \| UCHL1 \| DISEASES 23522 \| KAT6B \| DISEASES 4489 \| MT1A \| DISEASES 90525 \| SHF \| DISEASES 8209 \| C21orf33 \| DISEASES 729230 \| CCR2 \| DISEASES 2905 \| GRIN2C \| DISEASES 2215 \| FCGR3B \| DISEASES 72 \| ACTG2 \| DISEASES 886 \| CCKAR \| DISEASES 64320 \| RNF25 \| DISEASES 1359 \| CPA3 \| DISEASES 57159 \| TRIM54 \| DISEASES 256471 \| MFSD8 \| DISEASES 6228 \| RPS23 \| DISEASES 9311 \| ASIC3 \| DISEASES 6571 \| SLC18A2 \| DISEASES 9317 \| PTER \| DISEASES 92292 \| GLYATL1 \| DISEASES 4909 \| NTF4 \| DISEASES 10476 \| ATP5H \| DISEASES 56947 \| MFF \| DISEASES 3479 \| IGF1 \| DISEASES 143501 \| C11orf40 \| DISEASES 6870 \| TACR3 \| DISEASES 51181 \| DCXR \| DISEASES 6869 \| TACR1 \| DISEASES 2915 \| GRM5 \| DISEASES 3575 \| IL7R \| DISEASES 2353 \| FOS \| DISEASES 1473 \| CST5 \| DISEASES 11280 \| SCN11A \| DISEASES 27289 \| RND1 \| DISEASES 2147 \| F2 \| DISEASES 660 \| BMX \| DISEASES 5340 \| PLG \| DISEASES 51316 \| PLAC8 \| DISEASES 354 \| KLK3 \| DISEASES 6448 \| SGSH \| DISEASES 9377 \| COX5A \| DISEASES 8575 \| PRKRA \| DISEASES 27319 \| BHLHE22 \| DISEASES 1068 \| CETN1 \| DISEASES 60386 \| SLC25A19 \| DISEASES 147179 \| WIPF2 \| DISEASES 6863 \| TAC1 \| DISEASES 3157 \| HMGCS1 \| DISEASES 55 \| ACPP \| DISEASES 79054 \| TRPM8 \| DISEASES 5179 \| PENK \| DISEASES 29895 \| MYLPF \| DISEASES 286826 \| LIN9 \| DISEASES 8912 \| CACNA1H \| DISEASES 10732 \| TCFL5 \| DISEASES 338567 \| KCNK18 \| DISEASES 51738 \| GHRL \| DISEASES 885 \| CCK \| DISEASES 5025 \| P2RX4 \| DISEASES 4987 \| OPRL1 \| DISEASES 57142 \| RTN4 \| DISEASES 3363 \| HTR7 \| DISEASES 1982 \| EIF4G2 \| DISEASES 80320 \| SP6 \| DISEASES 132884 \| EVC2 \| DISEASES 10193 \| RNF41 \| DISEASES 22953 \| P2RX2 \| DISEASES 23463 \| ICMT \| DISEASES 11276 \| SYNRG \| DISEASES 1809 \| DPYSL3 \| DISEASES 3605 \| IL17A \| DISEASES 467 \| ATF3 \| DISEASES 94134 \| ARHGAP12 \| DISEASES 6925 \| TCF4 \| DISEASES 6334 \| SCN8A \| DISEASES 309 \| ANXA6 \| DISEASES 954 \| ENTPD2 \| DISEASES 3359 \| HTR3A \| DISEASES 10493 \| VAT1 \| DISEASES 23224 \| SYNE2 \| DISEASES 55010 \| PARPBP \| DISEASES 157680 \| VPS13B \| DISEASES 4149 \| MAX \| DISEASES 165679 \| SPTSSB \| DISEASES 3635 \| INPP5D \| DISEASES 773 \| CACNA1A \| DISEASES 1312 \| COMT \| DISEASES 4860 \| PNP \| DISEASES 388677 \| NOTCH2NL \| DISEASES 9937 \| DCLRE1A \| DISEASES 5083 \| PAX9 \| DISEASES 10223 \| GPA33 \| DISEASES 2214 \| FCGR3A \| DISEASES 4184 \| SMCP \| DISEASES 284486 \| THEM5 \| DISEASES 5654 \| HTRA1 \| DISEASES 5550 \| PREP \| DISEASES 4803 \| NGF \| DISEASES 257 \| ALX3 \| DISEASES 6785 \| ELOVL4 \| DISEASES 2316 \| FLNA \| DISEASES 282991 \| BLOC1S2 \| DISEASES 1369 \| CPN1 \| DISEASES 54558 \| SPATA6 \| DISEASES 6406 \| SEMG1 \| DISEASES 9469 \| CHST3 \| DISEASES 1025 \| CDK9 \| DISEASES 7099 \| TLR4 \| DISEASES 2582 \| GALE \| DISEASES 8325 \| FZD8 \| DISEASES 56288 \| PARD3 \| DISEASES 199 \| AIF1 \| DISEASES 10082 \| GPC6 \| DISEASES 114798 \| SLITRK1 \| DISEASES 3356 \| HTR2A \| DISEASES 2625 \| GATA3 \| DISEASES 5251 \| PHEX \| DISEASES 146 \| ADRA1D \| DISEASES 22944 \| KIN \| DISEASES 8544 \| PIR \| DISEASES 114131 \| UCN3 \| DISEASES 148 \| ADRA1A \| DISEASES 56897 \| WRNIP1 \| DISEASES 438 \| ASMT \| DISEASES 10675 \| CSPG5 \| DISEASES 9467 \| SH3BP5 \| DISEASES 83696 \| TRAPPC9 \| DISEASES 7247 \| TSN \| DISEASES 51429 \| SNX9 \| DISEASES 51347 \| TAOK3 \| DISEASES 654364 \| NME1-NME2 \| DISEASES 307 \| ANXA4 \| DISEASES 2719 \| GPC3 \| DISEASES 2962 \| GTF2F1 \| DISEASES 7041 \| TGFB1I1 \| DISEASES 100131390 \| SP9 \| DISEASES 3895 \| KTN1 \| DISEASES 27297 \| CRCP \| DISEASES 6387 \| CXCL12 \| DISEASES 9306 \| SOCS6 \| DISEASES 594857 \| NPS \| DISEASES 7110 \| TMF1 \| DISEASES 10606 \| PAICS \| DISEASES 7442 \| TRPV1 \| DISEASES 6335 \| SCN9A \| DISEASES 4295 \| MLN \| DISEASES 6336 \| SCN10A \| DISEASES 4988 \| OPRM1 \| DISEASES 4908 \| NTF3 \| DISEASES 7124 \| TNF \| DISEASES 139728 \| PNCK \| DISEASES 3586 \| IL10 \| DISEASES 627 \| BDNF \| DISEASES 346007 \| EYS \| DISEASES 4914 \| NTRK1 \| DISEASES 9152 \| SLC6A5 \| DISEASES 10978 \| CLP1 \| DISEASES 4190 \| MDH1 \| DISEASES 51271 \| UBAP1 \| DISEASES 8972 \| MGAM \| DISEASES 8437 \| RASAL1 \| DISEASES 9051 \| PSTPIP1 \| DISEASES 91056 \| AP5B1 \| DISEASES 820 \| CAMP \| DISEASES 2232 \| FDXR \| DISEASES 26085 \| KLK13 \| DISEASES 102723508 \| KANTR \| DISEASES
Locus	(Waiting for update.)

Disease ID	1286
Disease	somatoform disorder
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:7) HP:0000739 \| Anxiety \| 7 HP:0000716 \| Depression \| 6 HP:0012531 \| Pain \| 2 HP:0002315 \| Headaches \| 2 HP:0100785 \| Insomnia \| 1 HP:0012532 \| Chronic pain \| 1 HP:0007302 \| Bipolar disorder \| 1

Disease ID	1286
Disease	somatoform disorder
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:2) C0011570 \| depression \| 6 C0002020 \| alexithymia \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:3)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0037650	methylphenidate	D008774	113-45-1	somatoform disorders	MESH:D013001	marker/mechanism	17667474
C0037650	methylphenidate	D008774	113-45-1	somatoform disorders	MESH:D013001	therapeutic	12045757
C0037650	ribavirin	D012254	36791-04-5	somatoform disorders	MESH:D013001	marker/mechanism	12297606

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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