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PedAM

Pediatric Disease Annotations & Medicines



   sleep apnea
  

Disease ID 1057
Disease sleep apnea
Definition
Disorders characterized by multiple cessations of respirations during sleep that induce partial arousals and interfere with the maintenance of sleep. Sleep apnea syndromes are divided into central (see SLEEP APNEA, CENTRAL), obstructive (see SLEEP APNEA, OBSTRUCTIVE), and mixed central-obstructive types.
Synonym
[d]sleep apnea syndrome
[d]sleep apnea syndrome (context-dependent category)
[d]sleep apnea syndrome (situation)
[d]sleep apnoea syndrome
[d]syndrome sleep apnea
[d]syndrome sleep apnoea
apnea syndrome, sleep
apnea syndromes, sleep
apnea, sleep
apneas, sleep
breathing disorder during sleeping
breathing, sleep-disordered
hypopnea, sleep
hypopneas, sleep
sas - sleep apnea syndrome
sas - sleep apnoea syndrome
sleep apnea (disorder)
sleep apnea (finding)
sleep apnea nos
sleep apnea syndrome
sleep apnea syndromes
sleep apnea syndromes [disease/finding]
sleep apnea, nos
sleep apneas
sleep apnoea
sleep apnoea (disorder)
sleep apnoea syndrome
sleep disordered breathing
sleep hypopnea
sleep hypopneas
sleep hypopnoea
sleep-disordered breathing
syndrome sleep apnea
syndrome sleep apnoea
unspecified sleep apnea
DOID
UMLS
C0037315
MeSH
SNOMED-CT
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:244)
C0020538  |  hypertension  |  59
C0018801  |  heart failure  |  53
C0028754  |  obesity  |  48
C0042373  |  vascular disease  |  40
C0007222  |  cardiovascular disease  |  34
C0011847  |  diabetes  |  28
C0948265  |  metabolic syndrome  |  28
C0011860  |  type 2 diabetes  |  20
C0042373  |  vascular diseases  |  16
C0007222  |  cardiovascular diseases  |  14
C0010068  |  coronary artery disease  |  14
C0264716  |  chronic heart failure  |  13
C0004153  |  atherosclerosis  |  10
C0037317  |  sleep disturbance  |  10
C0018802  |  congestive heart failure  |  9
C0024117  |  chronic obstructive pulmonary disease  |  8
C0022658  |  kidney disease  |  8
C0011570  |  depression  |  8
C0017601  |  glaucoma  |  8
C0027051  |  myocardial infarction  |  8
C0020542  |  pulmonary hypertension  |  8
C0027051  |  myocardial infarct  |  8
C0018799  |  heart disease  |  7
C0017168  |  esophageal reflux  |  7
C0242350  |  erectile dysfunction  |  7
C0600260  |  obstructive pulmonary disease  |  7
C0017168  |  gastroesophageal reflux  |  7
C0017168  |  oesophageal reflux  |  7
C0011849  |  diabetes mellitus  |  7
C0155626  |  acute myocardial infarction  |  6
C0030567  |  parkinson's disease  |  6
C0034065  |  pulmonary embolism  |  6
C0024115  |  pulmonary disease  |  6
C0001206  |  acromegaly  |  6
C0028756  |  severe obesity  |  6
C0022661  |  chronic kidney disease  |  6
C0026769  |  multiple sclerosis  |  6
C0024115  |  lung disease  |  5
C0042373  |  vascular disorders  |  5
C0020538  |  systemic hypertension  |  5
C0042373  |  vascular disorder  |  5
C0010278  |  craniosynostosis  |  5
C0520679  |  obstructive sleep apnea  |  5
C0024117  |  chronic obstructive pulmonary disease (copd)  |  5
C0007222  |  cardiovascular disorders  |  5
C0271650  |  glucose intolerance  |  5
C0014544  |  epilepsy  |  5
C0679466  |  cognitive deficits  |  5
C0037315  |  sleep-disordered breathing  |  5
C0011860  |  type 2 diabetes mellitus  |  4
C0004096  |  asthma  |  4
C0023895  |  liver disease  |  4
C0028754  |  adiposity  |  4
C2607914  |  allergic rhinitis  |  4
C0037317  |  sleep disturbances  |  4
C0851578  |  sleep disorders  |  4
C0022578  |  keratoconus  |  3
C0020676  |  hypothyroidism  |  3
C0151740  |  intracranial hypertension  |  3
C1800706  |  idiopathic pulmonary fibrosis  |  3
C0017168  |  gastroesophageal reflux disease  |  3
C1561644  |  chronic kidney disease (ckd)  |  3
C0442874  |  neuropathy  |  3
C0751774  |  periodic limb movement  |  3
C0027404  |  narcolepsy  |  3
C1704436  |  peripheral arterial disease  |  3
C0003467  |  anxiety  |  3
C0497327  |  dementia  |  3
C0017168  |  esophageal reflux disease  |  3
C0034069  |  pulmonary fibrosis  |  3
C0005586  |  bipolar disorder  |  3
C0159069  |  impaired glucose tolerance  |  3
C0032461  |  polycythemia  |  2
C0010278  |  craniosynostosis syndromes  |  2
C0004763  |  barrett's esophagus  |  2
C0029132  |  optic neuropathy  |  2
C0085207  |  gestational diabetes  |  2
C0003090  |  ankylosis  |  2
C0022661  |  end-stage renal disease  |  2
C0007787  |  transient ischemic attack  |  2
C0018099  |  gout  |  2
C0271051  |  macular edema  |  2
C0007194  |  hypertrophic cardiomyopathy  |  2
C0035328  |  retinal vein occlusion  |  2
C0022116  |  ischemia  |  2
C0010068  |  coronary heart disease  |  2
C0852949  |  arterial disease  |  2
C0008924  |  cleft lip  |  2
C0878544  |  cardiomyopathy  |  2
C0751772  |  rem sleep behavior disorder  |  2
C0000889  |  acanthosis nigricans  |  2
C0003864  |  arthritis  |  2
C1145670  |  respiratory failure  |  2
C0024115  |  lung diseases  |  2
C0024796  |  marfan's syndrome  |  2
C0008925  |  cleft palate  |  2
C0013080  |  trisomy 21  |  2
C0035455  |  rhinitis  |  2
C1535927  |  charge syndrome  |  2
C0751711  |  anterior ischemic optic neuropathy  |  2
C0730285  |  diabetic macular edema  |  2
C0033953  |  sexual dysfunction  |  2
C0018824  |  valvular heart disease  |  2
C0030567  |  parkinson disease  |  2
C0003507  |  aortic stenosis  |  2
C0036341  |  schizophrenia  |  2
C0026703  |  mucopolysaccharidosis  |  2
C0038013  |  ankylosing spondylitis  |  2
C0038012  |  spondylitis  |  2
C0033845  |  idiopathic intracranial hypertension  |  2
C0206062  |  interstitial lung disease  |  2
C0003486  |  aortic aneurysm  |  2
C0035078  |  renal failure  |  2
C0600260  |  obstructive lung disease  |  1
C0393571  |  multiple system atrophy  |  1
C0040053  |  thrombosis  |  1
C1527336  |  sjogren's syndrome  |  1
C0431399  |  joubert syndrome  |  1
C0002395  |  alzheimer's disease  |  1
C0027051  |  myocardial infarction (mi)  |  1
C0740394  |  hyperuricemia  |  1
C0002895  |  sickle cell anemia  |  1
C0031099  |  periodontitis  |  1
C0032914  |  preeclampsia  |  1
C0020428  |  aldosteronism  |  1
C0011854  |  type 1 diabetes  |  1
C0238288  |  facioscapulohumeral muscular dystrophy  |  1
C0020538  |  hypertensive disorder  |  1
C0004779  |  gorlin syndrome  |  1
C0042075  |  urological diseases  |  1
C0024437  |  age-related macular degeneration  |  1
C1135191  |  systolic heart failure  |  1
C0013395  |  indigestion  |  1
C0162871  |  abdominal aortic aneurysms  |  1
C0003873  |  rheumatoid arthritis  |  1
C0751651  |  mitochondrial disease  |  1
C0149931  |  migraine  |  1
C0520679  |  obstructive sleep apnoea  |  1
C0014556  |  temporal lobe epilepsy  |  1
C0018799  |  cardiac disease  |  1
C0041696  |  major depression  |  1
C0018799  |  heart diseases  |  1
C0027765  |  neurological disorders  |  1
C0026703  |  mucopolysaccharidoses  |  1
C0006325  |  bruxism  |  1
C0027765  |  neurological disease  |  1
C0917796  |  leber hereditary optic neuropathy  |  1
C0259749  |  autonomic neuropathy  |  1
C0030319  |  panic disorder  |  1
C0030286  |  pancreatic disease  |  1
C0023890  |  cirrhosis  |  1
C0012236  |  22q11.2 deletion syndrome  |  1
C0023976  |  long qt syndrome  |  1
C0032460  |  polycystic ovary syndrome  |  1
C0751774  |  periodic limb movement disorder  |  1
C0339573  |  primary open-angle glaucoma  |  1
C0015469  |  facial paralysis  |  1
C0008780  |  primary ciliary dyskinesia  |  1
C0018916  |  hemangioma  |  1
C0035258  |  restless legs syndrome  |  1
C0010308  |  congenital hypothyroidism  |  1
C0018801  |  cardiac failure  |  1
C0206062  |  interstitial lung diseases  |  1
C0917996  |  cerebral aneurysm  |  1
C0022658  |  renal disease  |  1
C0271084  |  exudative age-related macular degeneration  |  1
C0029882  |  otitis media  |  1
C0024437  |  macular degeneration  |  1
C0600260  |  obstructive lung diseases  |  1
C0011269  |  vascular dementia  |  1
C0010273  |  crouzon syndrome  |  1
C0003486  |  aortic aneurysms  |  1
C0025281  |  meniere's disease  |  1
C0024796  |  marfan syndrome  |  1
C0036202  |  sarcoidosis  |  1
C0026948  |  mycosis fungoides  |  1
C0033687  |  proteinuria  |  1
C0035204  |  respiratory disease  |  1
C0520679  |  obstructive sleep apnoea syndrome  |  1
C0020456  |  hyperglycemia  |  1
C0017612  |  open-angle glaucoma  |  1
C0027765  |  neurological disorder  |  1
C0011884  |  diabetic retinopathy  |  1
C2697932  |  loeys-dietz syndrome  |  1
C0154437  |  atypical depression  |  1
C0040425  |  tonsillitis  |  1
C0238402  |  pycnodysostosis  |  1
C0949690  |  spondyloarthritis  |  1
C0020538  |  increased blood pressure  |  1
C0162871  |  abdominal aortic aneurysm  |  1
C0034072  |  cor pulmonale  |  1
C0042075  |  urological disorders  |  1
C0032461  |  polycythaemia  |  1
C0018024  |  retrosternal goitre  |  1
C0041696  |  major depressive disorder  |  1
C0033806  |  pseudohypoparathyroidism  |  1
C0027092  |  myopia  |  1
C0010276  |  craniopharyngioma  |  1
C1621895  |  adrenal hyperplasia  |  1
C0020428  |  hyperaldosteronism  |  1
C0040128  |  thyroid disease  |  1
C1318533  |  secondary polycythemia  |  1
C0035309  |  retinopathy  |  1
C0037315  |  sleep apnoea syndrome  |  1
C0020498  |  forestier disease  |  1
C0025235  |  melkersson-rosenthal syndrome  |  1
C0151740  |  increased intracranial pressure  |  1
C0151313  |  sensory neuropathy  |  1
C0853193  |  bipolar i disorder  |  1
C0032285  |  pneumonia  |  1
C0010054  |  coronary artery atherosclerosis  |  1
C0037315  |  sleep apnoea  |  1
C0003493  |  aortic disease  |  1
C0007570  |  celiac disease  |  1
C1619734  |  pulmonary arterial hypertension  |  1
C0003874  |  septic arthritis  |  1
C0022661  |  end-stage renal failure  |  1
C0028756  |  morbid obesity  |  1
C0026896  |  myasthenia gravis  |  1
C0026277  |  pleomorphic adenoma  |  1
C0085580  |  essential hypertension  |  1
C0007273  |  carotid artery disease  |  1
C0033375  |  prolactinoma  |  1
C0001627  |  congenital adrenal hyperplasia  |  1
C0033975  |  psychosis  |  1
C0085292  |  stiff-person syndrome  |  1
C0035435  |  rheumatic disease  |  1
C0018021  |  goitre  |  1
C0026850  |  muscular dystrophy  |  1
C0152136  |  normal tension glaucoma  |  1
C0003872  |  psoriatic arthritis  |  1
C0151620  |  hypertensive encephalopathy  |  1
C0035258  |  restless legs  |  1
C0010054  |  coronary atherosclerosis  |  1
C0037315  |  sleep apnea  |  1
C0154841  |  central retinal vein occlusion  |  1
C0151744  |  myocardial ischemia  |  1
C1956089  |  osteophytes  |  1
C0032460  |  polycystic ovary  |  1
C0009241  |  cognitive disorders  |  1
C0001430  |  adenoma  |  1
C1384514  |  primary aldosteronism  |  1
C0520680  |  central sleep apnea  |  1
C0035258  |  restless legs syndrome (rls)  |  1
Curated Gene
Entrez_id | Symbol | Resource(Total Genes:1)
BCHE  |  590  |  CTD_human
Inferring Gene
Entrez_id | Symbol | Resource(Total Genes:5)
2550  |  GABBR1  |  infer
3240  |  HP  |  infer
155  |  ADRB3  |  infer
7124  |  TNF  |  infer
348  |  APOE  |  infer
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:326)
54814  |  QPCTL  |  DISEASES
7132  |  TNFRSF1A  |  DISEASES
6583  |  SLC22A4  |  DISEASES
28954  |  REM1  |  DISEASES
23411  |  SIRT1  |  DISEASES
6634  |  SNRPD3  |  DISEASES
3162  |  HMOX1  |  DISEASES
5816  |  PVALB  |  DISEASES
328  |  APEX1  |  DISEASES
7076  |  TIMP1  |  DISEASES
479  |  ATP12A  |  DISEASES
4313  |  MMP2  |  DISEASES
1666  |  DECR1  |  DISEASES
56729  |  RETN  |  DISEASES
5444  |  PON1  |  DISEASES
10135  |  NAMPT  |  DISEASES
5054  |  SERPINE1  |  DISEASES
8985  |  PLOD3  |  DISEASES
5919  |  RARRES2  |  DISEASES
9487  |  PIGL  |  DISEASES
6347  |  CCL2  |  DISEASES
4621  |  MYH3  |  DISEASES
952  |  CD38  |  DISEASES
8929  |  PHOX2B  |  DISEASES
6783  |  SULT1E1  |  DISEASES
120237  |  DBX1  |  DISEASES
4048  |  LTA4H  |  DISEASES
3565  |  IL4  |  DISEASES
56920  |  SEMA3G  |  DISEASES
4057  |  LTF  |  DISEASES
338  |  APOB  |  DISEASES
6402  |  SELL  |  DISEASES
335  |  APOA1  |  DISEASES
9525  |  VPS4B  |  DISEASES
4852  |  NPY  |  DISEASES
3759  |  KCNJ2  |  DISEASES
11017  |  SNRNP27  |  DISEASES
2806  |  GOT2  |  DISEASES
2354  |  FOSB  |  DISEASES
51119  |  SBDS  |  DISEASES
3346  |  HTN1  |  DISEASES
27245  |  AHDC1  |  DISEASES
3630  |  INS  |  DISEASES
1911  |  PHC1  |  DISEASES
3741  |  KCNA5  |  DISEASES
348  |  APOE  |  DISEASES
4142  |  MAS1  |  DISEASES
2056  |  EPO  |  DISEASES
9104  |  RGN  |  DISEASES
8572  |  PDLIM4  |  DISEASES
57050  |  UTP3  |  DISEASES
1401  |  CRP  |  DISEASES
1131  |  CHRM3  |  DISEASES
4622  |  MYH4  |  DISEASES
1116  |  CHI3L1  |  DISEASES
284904  |  SEC14L4  |  DISEASES
2167  |  FABP4  |  DISEASES
759  |  CA1  |  DISEASES
1912  |  PHC2  |  DISEASES
3569  |  IL6  |  DISEASES
5004  |  ORM1  |  DISEASES
1419  |  CRYGB  |  DISEASES
1535  |  CYBA  |  DISEASES
64398  |  MPP5  |  DISEASES
6532  |  SLC6A4  |  DISEASES
23531  |  MMD  |  DISEASES
9480  |  ONECUT2  |  DISEASES
6521  |  SLC4A1  |  DISEASES
495  |  ATP4A  |  DISEASES
11316  |  COPE  |  DISEASES
25939  |  SAMHD1  |  DISEASES
84954  |  MPND  |  DISEASES
57084  |  SLC17A6  |  DISEASES
2033  |  EP300  |  DISEASES
50507  |  NOX4  |  DISEASES
3553  |  IL1B  |  DISEASES
28960  |  DCPS  |  DISEASES
54414  |  SIAE  |  DISEASES
6403  |  SELP  |  DISEASES
4162  |  MCAM  |  DISEASES
5443  |  POMC  |  DISEASES
8626  |  TP63  |  DISEASES
3383  |  ICAM1  |  DISEASES
6550  |  SLC9A3  |  DISEASES
3827  |  KNG1  |  DISEASES
10058  |  ABCB6  |  DISEASES
22937  |  SCAP  |  DISEASES
54806  |  AHI1  |  DISEASES
161253  |  REM2  |  DISEASES
597  |  BCL2A1  |  DISEASES
5678  |  PSG9  |  DISEASES
207  |  AKT1  |  DISEASES
93650  |  ACPT  |  DISEASES
402665  |  IGLON5  |  DISEASES
3782  |  KCNN3  |  DISEASES
5972  |  REN  |  DISEASES
185  |  AGTR1  |  DISEASES
54539  |  NDUFB11  |  DISEASES
4851  |  NOTCH1  |  DISEASES
133  |  ADM  |  DISEASES
3606  |  IL18  |  DISEASES
57105  |  CYSLTR2  |  DISEASES
57724  |  EPG5  |  DISEASES
9320  |  TRIP12  |  DISEASES
6750  |  SST  |  DISEASES
22808  |  MRAS  |  DISEASES
653361  |  NCF1  |  DISEASES
10481  |  HOXB13  |  DISEASES
1636  |  ACE  |  DISEASES
6285  |  S100B  |  DISEASES
9442  |  MED27  |  DISEASES
5675  |  PSG6  |  DISEASES
4056  |  LTC4S  |  DISEASES
3060  |  HCRT  |  DISEASES
7412  |  VCAM1  |  DISEASES
213  |  ALB  |  DISEASES
51304  |  ZDHHC3  |  DISEASES
4724  |  NDUFS4  |  DISEASES
81789  |  TIGD6  |  DISEASES
25862  |  USP49  |  DISEASES
4846  |  NOS3  |  DISEASES
115825  |  WDFY2  |  DISEASES
219793  |  TBATA  |  DISEASES
6236  |  RRAD  |  DISEASES
4640  |  MYO1A  |  DISEASES
4775  |  NFATC3  |  DISEASES
2819  |  GPD1  |  DISEASES
4054  |  LTBP3  |  DISEASES
116285  |  ACSM1  |  DISEASES
116844  |  LRG1  |  DISEASES
3479  |  IGF1  |  DISEASES
2357  |  FPR1  |  DISEASES
6869  |  TACR1  |  DISEASES
29071  |  C1GALT1C1  |  DISEASES
171558  |  PTCRA  |  DISEASES
8862  |  APLN  |  DISEASES
2548  |  GAA  |  DISEASES
81851  |  KRTAP1-1  |  DISEASES
2353  |  FOS  |  DISEASES
3777  |  KCNK3  |  DISEASES
27289  |  RND1  |  DISEASES
51316  |  PLAC8  |  DISEASES
169270  |  ZNF596  |  DISEASES
27129  |  HSPB7  |  DISEASES
836  |  CASP3  |  DISEASES
91464  |  ISX  |  DISEASES
133522  |  PPARGC1B  |  DISEASES
3952  |  LEP  |  DISEASES
55622  |  TTC27  |  DISEASES
5062  |  PAK2  |  DISEASES
5187  |  PER1  |  DISEASES
1909  |  EDNRA  |  DISEASES
53905  |  DUOX1  |  DISEASES
5680  |  PSG11  |  DISEASES
8289  |  ARID1A  |  DISEASES
9370  |  ADIPOQ  |  DISEASES
220032  |  GDPD4  |  DISEASES
6517  |  SLC2A4  |  DISEASES
6863  |  TAC1  |  DISEASES
23212  |  RRS1  |  DISEASES
10743  |  RAI1  |  DISEASES
7586  |  ZKSCAN1  |  DISEASES
199699  |  DAND5  |  DISEASES
2200  |  FBN1  |  DISEASES
3052  |  HCCS  |  DISEASES
64327  |  LMBR1  |  DISEASES
5034  |  P4HB  |  DISEASES
10945  |  KDELR1  |  DISEASES
842  |  CASP9  |  DISEASES
255324  |  EPGN  |  DISEASES
3953  |  LEPR  |  DISEASES
277  |  AMY1B  |  DISEASES
6401  |  SELE  |  DISEASES
29940  |  DSE  |  DISEASES
5671  |  PSG3  |  DISEASES
23768  |  FLRT2  |  DISEASES
5332  |  PLCB4  |  DISEASES
10732  |  TCFL5  |  DISEASES
10810  |  WASF3  |  DISEASES
51738  |  GHRL  |  DISEASES
1103  |  CHAT  |  DISEASES
3988  |  LIPA  |  DISEASES
10011  |  SRA1  |  DISEASES
3363  |  HTR7  |  DISEASES
3091  |  HIF1A  |  DISEASES
51337  |  THEM6  |  DISEASES
9402  |  GRAP2  |  DISEASES
3770  |  KCNJ14  |  DISEASES
7137  |  TNNI3  |  DISEASES
145264  |  SERPINA12  |  DISEASES
10166  |  SLC25A15  |  DISEASES
344901  |  OSTN  |  DISEASES
6633  |  SNRPD2  |  DISEASES
60490  |  PPCDC  |  DISEASES
5348  |  FXYD1  |  DISEASES
390259  |  BSX  |  DISEASES
5673  |  PSG5  |  DISEASES
57492  |  ARID1B  |  DISEASES
2879  |  GPX4  |  DISEASES
50618  |  ITSN2  |  DISEASES
4010  |  LMX1B  |  DISEASES
6720  |  SREBF1  |  DISEASES
6651  |  SON  |  DISEASES
3084  |  NRG1  |  DISEASES
6714  |  SRC  |  DISEASES
26057  |  ANKRD17  |  DISEASES
56980  |  PRDM10  |  DISEASES
11086  |  ADAM29  |  DISEASES
6241  |  RRM2  |  DISEASES
1565  |  CYP2D6  |  DISEASES
5167  |  ENPP1  |  DISEASES
8532  |  CPZ  |  DISEASES
6721  |  SREBF2  |  DISEASES
56259  |  CTNNBL1  |  DISEASES
9937  |  DCLRE1A  |  DISEASES
183  |  AGT  |  DISEASES
22796  |  COG2  |  DISEASES
2590  |  GALNT2  |  DISEASES
7139  |  TNNT2  |  DISEASES
5743  |  PTGS2  |  DISEASES
8991  |  SELENBP1  |  DISEASES
4170  |  MCL1  |  DISEASES
153  |  ADRB1  |  DISEASES
8266  |  UBL4A  |  DISEASES
50861  |  STMN3  |  DISEASES
278  |  AMY1C  |  DISEASES
276  |  AMY1A  |  DISEASES
959  |  CD40LG  |  DISEASES
55361  |  PI4K2A  |  DISEASES
9532  |  BAG2  |  DISEASES
1491  |  CTH  |  DISEASES
1791  |  DNTT  |  DISEASES
6005  |  RHAG  |  DISEASES
5730  |  PTGDS  |  DISEASES
154796  |  AMOT  |  DISEASES
7422  |  VEGFA  |  DISEASES
6441  |  SFTPD  |  DISEASES
729238  |  SFTPA2  |  DISEASES
4318  |  MMP9  |  DISEASES
79717  |  PPCS  |  DISEASES
1979  |  EIF4EBP2  |  DISEASES
10800  |  CYSLTR1  |  DISEASES
2170  |  FABP3  |  DISEASES
7099  |  TLR4  |  DISEASES
6572  |  SLC18A3  |  DISEASES
7295  |  TXN  |  DISEASES
1896  |  EDA  |  DISEASES
177  |  AGER  |  DISEASES
3055  |  HCK  |  DISEASES
4879  |  NPPB  |  DISEASES
4878  |  NPPA  |  DISEASES
1471  |  CST3  |  DISEASES
160897  |  GPR180  |  DISEASES
81562  |  LMAN2L  |  DISEASES
116511  |  MAS1L  |  DISEASES
10159  |  ATP6AP2  |  DISEASES
1536  |  CYBB  |  DISEASES
3356  |  HTR2A  |  DISEASES
5251  |  PHEX  |  DISEASES
1906  |  EDN1  |  DISEASES
25820  |  ARIH1  |  DISEASES
390598  |  SKOR1  |  DISEASES
551  |  AVP  |  DISEASES
6462  |  SHBG  |  DISEASES
241  |  ALOX5AP  |  DISEASES
3486  |  IGFBP3  |  DISEASES
7054  |  TH  |  DISEASES
9189  |  ZBED1  |  DISEASES
11082  |  ESM1  |  DISEASES
55835  |  CENPJ  |  DISEASES
26278  |  SACS  |  DISEASES
81623  |  DEFB126  |  DISEASES
6545  |  SLC7A4  |  DISEASES
1133  |  CHRM5  |  DISEASES
9467  |  SH3BP5  |  DISEASES
94  |  ACVRL1  |  DISEASES
56953  |  NT5M  |  DISEASES
50506  |  DUOX2  |  DISEASES
83696  |  TRAPPC9  |  DISEASES
11262  |  SP140  |  DISEASES
3703  |  STT3A  |  DISEASES
55188  |  RIC8B  |  DISEASES
23041  |  MON2  |  DISEASES
2596  |  GAP43  |  DISEASES
51520  |  LARS  |  DISEASES
64115  |  C10orf54  |  DISEASES
594857  |  NPS  |  DISEASES
84709  |  MGARP  |  DISEASES
375704  |  ENHO  |  DISEASES
56903  |  PAPOLB  |  DISEASES
5672  |  PSG4  |  DISEASES
5670  |  PSG2  |  DISEASES
3778  |  KCNMA1  |  DISEASES
55660  |  PRPF40A  |  DISEASES
1123  |  CHN1  |  DISEASES
199800  |  ADM5  |  DISEASES
197  |  AHSG  |  DISEASES
6503  |  SLA  |  DISEASES
23705  |  CADM1  |  DISEASES
3550  |  IK  |  DISEASES
653509  |  SFTPA1  |  DISEASES
7124  |  TNF  |  DISEASES
4615  |  MYD88  |  DISEASES
4152  |  MBD1  |  DISEASES
54900  |  LAX1  |  DISEASES
1132  |  CHRM4  |  DISEASES
2263  |  FGFR2  |  DISEASES
4140  |  MARK3  |  DISEASES
3586  |  IL10  |  DISEASES
627  |  BDNF  |  DISEASES
8842  |  PROM1  |  DISEASES
2638  |  GC  |  DISEASES
100506742  |  CASP12  |  DISEASES
3347  |  HTN3  |  DISEASES
83695  |  RHNO1  |  DISEASES
1649  |  DDIT3  |  DISEASES
2972  |  BRF1  |  DISEASES
101  |  ADAM8  |  DISEASES
389422  |  C6orf183  |  DISEASES
7138  |  TNNT1  |  DISEASES
79990  |  PLEKHH3  |  DISEASES
102191832  |  FBXW7-AS1  |  DISEASES
102723508  |  KANTR  |  DISEASES
104564225  |  MHRT  |  DISEASES
780851  |  SNORD3A  |  DISEASES
26807  |  SNORD43  |  DISEASES
Locus(Waiting for update.)
Disease ID 1057
Disease sleep apnea
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:202)
HP:0001635  |  Congestive heart failure  |  65
HP:0001262  |  Somnolence  |  63
HP:0000822  |  Hypertension  |  60
HP:0001513  |  Obesity  |  45
HP:0040213  |  Hypopnea  |  24
HP:0002104  |  Absence of spontaneous respiration  |  24
HP:0001297  |  Cerebral vascular events  |  24
HP:0100543  |  Cognitive deficits  |  19
HP:0100785  |  Insomnia  |  16
HP:0005110  |  Atrial fibrillation  |  15
HP:0002189  |  Excessive daytime sleepiness  |  15
HP:0001677  |  Coronary artery disease  |  14
HP:0012196  |  Periodic respiration  |  14
HP:0012418  |  Low blood oxygen level  |  14
HP:0000855  |  Insulin resistance  |  13
HP:0100786  |  Excessive sleepiness  |  12
HP:0011675  |  Arrhythmias  |  11
HP:0002360  |  Sleep disturbance  |  10
HP:0012378  |  Fatigue  |  10
HP:0002621  |  Atherosclerosis  |  10
HP:0002781  |  Upper airway obstruction  |  9
HP:0002140  |  Ischemic stroke  |  9
HP:0002020  |  Heartburn  |  9
HP:0006510  |  Chronic obstructive pulmonary disease  |  8
HP:0030812  |  Tonsillar hypertrophy  |  8
HP:0000716  |  Depression  |  8
HP:0000501  |  Glaucoma  |  8
HP:0001658  |  Myocardial infarction  |  8
HP:0000833  |  Glucose intolerance  |  8
HP:0002092  |  Pulmonary artery hypertension  |  8
HP:0002315  |  Headaches  |  8
HP:0002791  |  Under breathing  |  7
HP:0000819  |  Diabetes mellitus  |  7
HP:0000802  |  Erectile dysfunction  |  7
HP:0012622  |  Chronic kidney disease  |  6
HP:0000845  |  Acromegalic growth  |  6
HP:0001363  |  Early fusion of cranial sutures  |  6
HP:0012416  |  Hypercarbia  |  6
HP:0002459  |  Dysautonomia  |  6
HP:0000805  |  Enuresis  |  6
HP:0000017  |  Nocturia  |  5
HP:0002204  |  Pulmonary embolism  |  5
HP:0002870  |  Obstructive sleep apnea  |  5
HP:0001824  |  Weight loss  |  5
HP:0003193  |  Allergic rhinitis  |  4
HP:0001397  |  Hepatic steatosis  |  4
HP:0010677  |  Enuresis nocturna  |  4
HP:0000201  |  Pierre-robin deformity  |  4
HP:0002099  |  Asthma  |  4
HP:0001742  |  Obstruction of nose  |  4
HP:0002329  |  Drowsiness  |  4
HP:0003774  |  End-stage renal failure  |  4
HP:0012384  |  Nasal inflammation  |  4
HP:0012531  |  Pain  |  4
HP:0002516  |  Intracranial pressure elevation  |  3
HP:0005321  |  Mandibulofacial dysostosis  |  3
HP:0000739  |  Anxiety  |  3
HP:0002308  |  Chiari malformation  |  3
HP:0000821  |  Underactive thyroid  |  3
HP:0002871  |  Central apnea  |  3
HP:0002326  |  TIA  |  3
HP:0007302  |  Bipolar disorder  |  3
HP:0000726  |  Dementia  |  3
HP:0004950  |  Peripheral artery disease  |  3
HP:0000563  |  Conical cornea  |  3
HP:0001997  |  Gout  |  3
HP:0030050  |  Narcolepsy  |  3
HP:0002206  |  Pulmonary fibrosis  |  3
HP:0040049  |  Macular edema  |  2
HP:0001638  |  Cardiomyopathy  |  2
HP:0002617  |  Aneurysmal dilatation  |  2
HP:0002149  |  Hyperuricemia  |  2
HP:0100753  |  Schizophrenia  |  2
HP:0001901  |  Abnormally shaped erythrocytes  |  2
HP:0011800  |  Midface, flat  |  2
HP:0002878  |  Respiratory failure  |  2
HP:0010535  |  Sleep apnea  |  2
HP:0012636  |  Retinal vein occlusion  |  2
HP:0006530  |  Interstitial lung disease  |  2
HP:0001694  |  Right-to-left shunt  |  2
HP:0001650  |  Valvular aortic stenosis  |  2
HP:0000175  |  Palatoschisis  |  2
HP:0001510  |  Growth deficiency  |  2
HP:0007099  |  Arnold Chiari type I malformation  |  2
HP:0005943  |  Respiratory arrest  |  2
HP:0001369  |  Arthritis  |  2
HP:0012532  |  Chronic pain  |  2
HP:0007634  |  Nonarteritic anterior ischemic optic neuropathy  |  2
HP:0100580  |  Barrett's esophagus  |  2
HP:0002094  |  Dyspnea  |  2
HP:0009800  |  gestational diabetes  |  2
HP:0001138  |  Damaged optic nerve  |  2
HP:0001639  |  Hypertrophic cardiomyopathy  |  2
HP:0000083  |  Renal insufficiency  |  2
HP:0000752  |  Hyperactive behavior  |  2
HP:0000956  |  Keratosis nigricans  |  2
HP:0004942  |  Aortic aneurysm  |  2
HP:0001601  |  Laryngomalacia  |  1
HP:0200136  |  Oral-pharyngeal dysphagia  |  1
HP:0000859  |  Mineralocorticoid excess  |  1
HP:0001298  |  Encephalopathy  |  1
HP:0000709  |  Psychosis  |  1
HP:0002475  |  Myelomeningocele  |  1
HP:0000147  |  Sclerocystic ovaries  |  1
HP:0003077  |  Hyperlipidemia  |  1
HP:0030062  |  Craniopharyngioma  |  1
HP:0007018  |  Attention deficits  |  1
HP:0000763  |  Sensory neuropathy  |  1
HP:0000608  |  Macular degeneration  |  1
HP:0002090  |  Pneumonia  |  1
HP:0001028  |  Strawberry mark  |  1
HP:0003394  |  Muscle cramps  |  1
HP:0012478  |  Temporomandibular joint ankylosis  |  1
HP:0000713  |  Agitation  |  1
HP:0000093  |  Proteinuria  |  1
HP:0008970  |  Scapulohumeral muscular dystrophy  |  1
HP:0001944  |  Dehydration  |  1
HP:0030731  |  Carcinoma  |  1
HP:0001907  |  Thromboembolic disease  |  1
HP:0001399  |  Liver failure  |  1
HP:0001657  |  Prolonged QT interval  |  1
HP:0002647  |  Aortic dissection  |  1
HP:0007868  |  ARMD  |  1
HP:0001724  |  Aortic dilatation  |  1
HP:0003763  |  Bruxism  |  1
HP:0002635  |  Atheromatosis  |  1
HP:0000545  |  Near sightedness  |  1
HP:0002625  |  Blood clot in a deep vein  |  1
HP:0000327  |  Maxillary micrognathia  |  1
HP:0001605  |  Vocal cord paralysis  |  1
HP:0002608  |  Celiac disease  |  1
HP:0000975  |  Increased sweating  |  1
HP:0004308  |  Ventricular arrhythmia  |  1
HP:0001662  |  Bradycardia  |  1
HP:0001717  |  Coronary artery calcification  |  1
HP:0002664  |  Neoplasia  |  1
HP:0001645  |  Sudden cardiac death  |  1
HP:0008221  |  Enlarged adrenal glands  |  1
HP:0010307  |  Stridor  |  1
HP:0000787  |  Renal calculi  |  1
HP:0002076  |  Migraine headaches  |  1
HP:0000851  |  Congenital hypothyroidism  |  1
HP:0003473  |  Fatigable weakness  |  1
HP:0002354  |  Memory loss  |  1
HP:0004927  |  Pulmonary artery dilatation  |  1
HP:0009118  |  Hypoplasia of lower jaw  |  1
HP:0012820  |  Bilateral vocal cord paralysis  |  1
HP:0011110  |  Inflammation of tonsils  |  1
HP:0001250  |  Seizures  |  1
HP:0004953  |  Abdominal aortic aneurysm  |  1
HP:0012592  |  Albuminuria  |  1
HP:0000969  |  Dropsy  |  1
HP:0003074  |  High blood glucose  |  1
HP:0012743  |  Central obesity  |  1
HP:0004439  |  Crouzon syndrome  |  1
HP:0000488  |  Noninflammatory retina disease  |  1
HP:0004944  |  Cerebral artery aneurysm  |  1
HP:0006536  |  Obstructive lung disease  |  1
HP:0004936  |  Blood clot in vein  |  1
HP:0012199  |  Cluster headache  |  1
HP:0000303  |  Increased size of lower jaw  |  1
HP:0100602  |  Pre-eclampsia  |  1
HP:0008220  |  Glucocorticoid insufficiency  |  1
HP:0000853  |  Goitre  |  1
HP:0007209  |  Facial paresis  |  1
HP:0000704  |  Pyorrhea  |  1
HP:0001648  |  Cor pulmonale  |  1
HP:0001342  |  Intracerebral hemorrhage  |  1
HP:0100827  |  Lymphocytosis  |  1
HP:0000347  |  Hypoplasia of mandible  |  1
HP:0000470  |  Decreased cervical height  |  1
HP:0012265  |  Ciliary dyskinesia  |  1
HP:0010536  |  Central sleep apnoea  |  1
HP:0002015  |  Swallowing difficulty  |  1
HP:0100806  |  Sepsis  |  1
HP:0001394  |  Hepatic cirrhosis  |  1
HP:0100022  |  Movement disorder  |  1
HP:0001370  |  Rheumatoid arthritis  |  1
HP:0003095  |  Septic arthritis  |  1
HP:0000924  |  Abnormality of the skeletal system  |  1
HP:0003560  |  Muscular dystrophy  |  1
HP:0002098  |  Respiratory distress  |  1
HP:0000103  |  Polyuria  |  1
HP:0001268  |  Mental deterioration  |  1
HP:0008071  |  Maternal hypertension  |  1
HP:0000689  |  Misalignment of upper and lower dental arches  |  1
HP:0012722  |  Heart block  |  1
HP:0002597  |  Abnormality of blood vessels  |  1
HP:0004929  |  Coronary artherosclerosis  |  1
HP:0005957  |  Abnormal breathing  |  1
HP:0008258  |  Congenital adrenal hyperplasia  |  1
HP:0000820  |  Thyroid abnormality  |  1
HP:0000852  |  Pseudohypoparathyroidism  |  1
HP:0012228  |  Tension-type headache  |  1
HP:0002171  |  Cerebral gliosis  |  1
HP:0000388  |  Otitis media  |  1
HP:0012452  |  Restless legs  |  1
HP:0002091  |  Restrictive ventilatory defect  |  1
HP:0004749  |  Atrial flutter  |  1
HP:0012594  |  High urine albumin levels  |  1
HP:0001649  |  Tachycardia  |  1
HP:0003470  |  Inability to move  |  1
Disease ID 1057
Disease sleep apnea
Manually Symptom(Waiting for update.)
Text Mined Symptom
UMLS | Name | Sentences' Count(Total Symptoms:41)
C0020538  |  hypertension  |  56
C0028754  |  obesity  |  36
C0007222  |  cardiovascular disease  |  28
C0037384  |  snoring  |  17
C1301700  |  cardiovascular morbidity  |  14
C0001883  |  airway obstruction  |  14
C0694563  |  excessive daytime sleepiness  |  13
C0740852  |  upper airway obstruction  |  9
C0011570  |  depression  |  8
C0018801  |  heart failure  |  8
C0004153  |  atherosclerosis  |  8
C0242350  |  erectile dysfunction  |  7
C1393529  |  vascular complications  |  7
C0017601  |  glaucoma  |  7
C0011849  |  diabetes mellitus  |  6
C0018802  |  congestive heart failure  |  5
C0679466  |  cognitive deficits  |  5
C0020440  |  hypercapnia  |  5
C0018681  |  headache  |  4
C0014394  |  enuresis  |  4
C0001206  |  acromegaly  |  3
C0025517  |  metabolic disorders  |  3
C0020676  |  hypothyroidism  |  3
C2219848  |  daytime somnolence  |  3
C0017168  |  gastroesophageal reflux  |  2
C1852242  |  nonarteritic anterior ischemic optic neuropathy  |  2
C0033953  |  sexual dysfunction  |  2
C0428837  |  coronary collateral circulation  |  1
C0581880  |  morning headache  |  1
C0035258  |  restless legs syndrome  |  1
C0021308  |  infarction  |  1
C0948089  |  acute coronary syndrome  |  1
C0262405  |  brain dysfunction  |  1
C1257958  |  disorders of glucose metabolism  |  1
C0577631  |  carotid atherosclerosis  |  1
C0029132  |  optic neuropathy  |  1
C0422833  |  ent symptoms  |  1
C0009088  |  cluster headache  |  1
C0033687  |  proteinuria  |  1
C0010068  |  coronary artery disease  |  1
C0027051  |  myocardial infarct  |  1
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:0)
(Waiting for update.)
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)
Mapped by lexical matching(Total Items:0)
(Waiting for update.)
Mapped by homologous gene(Total Items:0)
(Waiting for update.)
Chemical(Total Drugs:4)
CUI ChemicalName ChemicalID CasRN DiseaseName DiseaseID DirectEvidence PubMedIDs
C0037315codeineD00306176-57-3sleep apnea syndromesMESH:D012891marker/mechanism17564651
C0037315mirtazapineC035133-sleep apnea syndromesMESH:D012891therapeutic16625567
C0037315phenylephrineD01065659-42-7sleep apnea syndromesMESH:D012891marker/mechanism1537703
C0037315succinylcholineD013390306-40-1sleep apnea syndromesMESH:D012891marker/mechanism18555211
FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)
FDA labeling changes(Total Drugs:0)
(Waiting for update.)