sexual disorder |
Disease ID | 1567 |
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Disease | sexual disorder |
Integrated Phenotype | (Waiting for update.) |
Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:5) HP:0012876 | Premature ejaculation | 2 HP:0000819 | Diabetes mellitus | 2 HP:0000054 | Short penis | 1 HP:0000789 | Infertility | 1 HP:0000020 | Bladder incontinence | 1 |
Disease ID | 1567 |
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Disease | sexual disorder |
Manually Symptom | (Waiting for update.) |
Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
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(Waiting for update.) |
All Snps(Total Genotypes:6) | |||||||||||||
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snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
rs1045642 | 23356581 | 5243 | ABCB1 | umls:C0549622 | BeFree | This study measured functionally implicated ABCB1 variants (rs2235015, rs1128503, rs2032582, and rs1045642) and sexual dysfunction using the Changes in Sexual Functioning Questionnaire. | 0.000542884 | 2013 | ABCB1 | 7 | 87509329 | A | T,G |
rs1128503 | 23356581 | 5243 | ABCB1 | umls:C0549622 | BeFree | This study measured functionally implicated ABCB1 variants (rs2235015, rs1128503, rs2032582, and rs1045642) and sexual dysfunction using the Changes in Sexual Functioning Questionnaire. | 0.000542884 | 2013 | ABCB1 | 7 | 87550285 | A | G |
rs1160351 | 22445761 | 161357 | MDGA2 | umls:C0549622 | GWASCAT | Genome-wide association study of SSRI/SNRI-induced sexual dysfunction in a Japanese cohort with major depression. | 0.12 | 2012 | MDGA2 | 14 | 47546779 | A | C |
rs13436218 | 22445761 | 171019 | ADAMTS19 | umls:C0549622 | GWASCAT | Genome-wide association study of SSRI/SNRI-induced sexual dysfunction in a Japanese cohort with major depression. | 0.12 | 2012 | ADAMTS19 | 5 | 129664693 | T | G |
rs2032582 | 23356581 | 5243 | ABCB1 | umls:C0549622 | BeFree | This study measured functionally implicated ABCB1 variants (rs2235015, rs1128503, rs2032582, and rs1045642) and sexual dysfunction using the Changes in Sexual Functioning Questionnaire. | 0.000542884 | 2013 | ABCB1 | 7 | 87531302 | A | T,C |
rs2235015 | 23356581 | 5243 | ABCB1 | umls:C0549622 | BeFree | This study measured functionally implicated ABCB1 variants (rs2235015, rs1128503, rs2032582, and rs1045642) and sexual dysfunction using the Changes in Sexual Functioning Questionnaire. | 0.000542884 | 2013 | ABCB1 | 7 | 87570248 | C | A |
GWASdb Annotation(Total Genotypes:0) | |
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(Waiting for update.) |
GWASdb Snp Trait(Total Genotypes:22) | |||||||||||||||||||||||||||||
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CHR | POS | SNPID | REF | ALT | ORI_SNPID | PMID | P_VALUE | P_VALUE_TEXT | OR/BETA | CI95_TEXT | GWAS_INITIAL_SAMPLE_SIZE | SUB_POPULATION | SUPER_POPULATION | GWAS_TRAIT | HPO_ID | HPO_TERM | DO_ID | DO_TERM | MESH_ID | MESH_TERM | EFO_ID | EFO_TERM | DOLITE_TERM | RISK_ALLELE | PUBLICATION_TYPE | AA | GENE_SYMBOL | TYPE | REFGENE |
1 | 197020658 | rs2990510 | T | G | rs2990510 | 22704111 | 6.00E-06 | NA | NA | NA | 125 European ancestry Erectile dysfunction cases with Type 1 Diabetes; 403 European ancestry non Erectile dysfunction controls with Type 1 Diabetes | European(528) | ALL(528) | EUR(528) | ALL(528) | Erectile dysfunction | HPOID:0000802 | Impotence | DOID:1876 | sexual dysfunction | D007172 | Erectile Dysfunction | EFOID:0004234 | type i diabetes mellitus | Testicular dysfunction | Ovarian failure | rs2990510-G | Randomized Controlled Trial | Multicenter Study |
2 | 111797458 | rs17483466 | A | G | rs17483466 | 22704111 | 4.96E-09 | NA | NA | NA | 125 European ancestry Erectile dysfunction cases with Type 1 Diabetes; 403 European ancestry non Erectile dysfunction controls with Type 1 Diabetes | European(528) | ALL(528) | EUR(528) | ALL(528) | Erectile dysfunction | HPOID:0000802 | Impotence | DOID:1876 | sexual dysfunction | D007172 | Erectile Dysfunction | EFOID:0004234 | type i diabetes mellitus | Testicular dysfunction | Ovarian failure | NA | Randomized Controlled Trial | Multicenter Study |
2 | 173493078 | rs836589 | A | G | rs836589 | 22704111 | 2.00E-06 | NA | NA | NA | 125 European ancestry Erectile dysfunction cases with Type 1 Diabetes; 403 European ancestry non Erectile dysfunction controls with Type 1 Diabetes | European(528) | ALL(528) | EUR(528) | ALL(528) | Erectile dysfunction | HPOID:0000802 | Impotence | DOID:1876 | sexual dysfunction | D007172 | Erectile Dysfunction | EFOID:0004234 | type i diabetes mellitus | Testicular dysfunction | Ovarian failure | rs836589-A | Randomized Controlled Trial | Multicenter Study |
2 | 231091223 | rs13397985 | T | G | rs13397985 | 22704111 | 1.75E-07 | NA | NA | NA | 125 European ancestry Erectile dysfunction cases with Type 1 Diabetes; 403 European ancestry non Erectile dysfunction controls with Type 1 Diabetes | European(528) | ALL(528) | EUR(528) | ALL(528) | Erectile dysfunction | HPOID:0000802 | Impotence | DOID:1876 | sexual dysfunction | D007172 | Erectile Dysfunction | EFOID:0004234 | type i diabetes mellitus | Testicular dysfunction | Ovarian failure | NA | Randomized Controlled Trial | Multicenter Study |
2 | 242371101 | rs757978 | C | T | rs757978 | 22704111 | 3.21E-06 | NA | NA | NA | 125 European ancestry Erectile dysfunction cases with Type 1 Diabetes; 403 European ancestry non Erectile dysfunction controls with Type 1 Diabetes | European(528) | ALL(528) | EUR(528) | ALL(528) | Erectile dysfunction | HPOID:0000802 | Impotence | DOID:1876 | sexual dysfunction | D007172 | Erectile Dysfunction | EFOID:0004234 | type i diabetes mellitus | Testicular dysfunction | Ovarian failure | NA | Randomized Controlled Trial | Multicenter Study |
3 | 36680099 | rs950146 | G | T | rs950146 | 22704111 | 4.00E-06 | NA | NA | NA | 125 European ancestry Erectile dysfunction cases with Type 1 Diabetes; 403 European ancestry non Erectile dysfunction controls with Type 1 Diabetes | European(528) | ALL(528) | EUR(528) | ALL(528) | Erectile dysfunction | HPOID:0000802 | Impotence | DOID:1876 | sexual dysfunction | D007172 | Erectile Dysfunction | EFOID:0004234 | type i diabetes mellitus | Testicular dysfunction | Ovarian failure | rs950146-C | Randomized Controlled Trial | Multicenter Study |
3 | 80865764 | rs9850225 | G | C | rs9850225 | 22704111 | 5.00E-08 | NA | NA | NA | 125 European ancestry Erectile dysfunction cases with Type 1 Diabetes; 403 European ancestry non Erectile dysfunction controls with Type 1 Diabetes | European(528) | ALL(528) | EUR(528) | ALL(528) | Erectile dysfunction | HPOID:0000802 | Impotence | DOID:1876 | sexual dysfunction | D007172 | Erectile Dysfunction | EFOID:0004234 | type i diabetes mellitus | Testicular dysfunction | Ovarian failure | rs9850224-A | Randomized Controlled Trial | Multicenter Study |
3 | 105010890 | rs9810233 | A | G | rs9810233 | 22704111 | 7.00E-07 | NA | NA | NA | 125 European ancestry Erectile dysfunction cases with Type 1 Diabetes; 403 European ancestry non Erectile dysfunction controls with Type 1 Diabetes | European(528) | ALL(528) | EUR(528) | ALL(528) | Erectile dysfunction | HPOID:0000802 | Impotence | DOID:1876 | sexual dysfunction | D007172 | Erectile Dysfunction | EFOID:0004234 | type i diabetes mellitus | Testicular dysfunction | Ovarian failure | rs9810233-G | Randomized Controlled Trial | Multicenter Study |
5 | 129000386 | rs13436218 | T | G | rs13436218 | 22445761 | 1.00E-06 | NA | 5.92 | [4.67-7.52] | 201 Japanese ancestry individuals | Japanese(201) | ALL(201) | ASN(201) | ALL(201) | Sexual dysfunction (SSRI/SNRI-related) | HPOID:0000078 | Abnormality of the genital system | DOID:1876 | sexual dysfunction | D020018 | Sexual Dysfunctions, Psychological | NA | NA | Testicular dysfunction | Ovarian failure | rs13436218-C | Research Support, Non-U.S. Gov't | G |
6 | 411064 | rs872071 | A | G | rs872071 | 22704111 | 7.54E-14 | NA | NA | NA | 125 European ancestry Erectile dysfunction cases with Type 1 Diabetes; 403 European ancestry non Erectile dysfunction controls with Type 1 Diabetes | European(528) | ALL(528) | EUR(528) | ALL(528) | Erectile dysfunction | HPOID:0000802 | Impotence | DOID:1876 | sexual dysfunction | D007172 | Erectile Dysfunction | EFOID:0004234 | type i diabetes mellitus | Testicular dysfunction | Ovarian failure | NA | Randomized Controlled Trial | Multicenter Study |
6 | 417727 | rs9378805 | A | C | rs9378805 | 22704111 | 3.22E-11 | NA | NA | NA | 125 European ancestry Erectile dysfunction cases with Type 1 Diabetes; 403 European ancestry non Erectile dysfunction controls with Type 1 Diabetes | European(528) | ALL(528) | EUR(528) | ALL(528) | Erectile dysfunction | HPOID:0000802 | Impotence | DOID:1876 | sexual dysfunction | D007172 | Erectile Dysfunction | EFOID:0004234 | type i diabetes mellitus | Testicular dysfunction | Ovarian failure | NA | Randomized Controlled Trial | Multicenter Study |
6 | 144079854 | rs6931865 | A | G | rs6931865 | 22704111 | 4.00E-06 | NA | NA | NA | 125 European ancestry Erectile dysfunction cases with Type 1 Diabetes; 403 European ancestry non Erectile dysfunction controls with Type 1 Diabetes | European(528) | ALL(528) | EUR(528) | ALL(528) | Erectile dysfunction | HPOID:0000802 | Impotence | DOID:1876 | sexual dysfunction | D007172 | Erectile Dysfunction | EFOID:0004234 | type i diabetes mellitus | Testicular dysfunction | Ovarian failure | rs6931865-A | Randomized Controlled Trial | Multicenter Study |
8 | 128192981 | rs2456449 | A | G | rs2456449 | 22704111 | 6.31E-04 | NA | NA | NA | 125 European ancestry Erectile dysfunction cases with Type 1 Diabetes; 403 European ancestry non Erectile dysfunction controls with Type 1 Diabetes | European(528) | ALL(528) | EUR(528) | ALL(528) | Erectile dysfunction | HPOID:0000802 | Impotence | DOID:1876 | sexual dysfunction | D007172 | Erectile Dysfunction | EFOID:0004234 | type i diabetes mellitus | Testicular dysfunction | Ovarian failure | NA | Randomized Controlled Trial | Multicenter Study |
11 | 123361397 | rs735665 | G | A | rs735665 | 22704111 | 3.36E-12 | NA | NA | NA | 125 European ancestry Erectile dysfunction cases with Type 1 Diabetes; 403 European ancestry non Erectile dysfunction controls with Type 1 Diabetes | European(528) | ALL(528) | EUR(528) | ALL(528) | Erectile dysfunction | HPOID:0000802 | Impotence | DOID:1876 | sexual dysfunction | D007172 | Erectile Dysfunction | EFOID:0004234 | type i diabetes mellitus | Testicular dysfunction | Ovarian failure | NA | Randomized Controlled Trial | Multicenter Study |
14 | 30594657 | rs225848 | G | A | rs225848 | 22445761 | 1.00E-06 | NA | 4.42 | [2.12-9.26] | 201 Japanese ancestry individuals | Japanese(201) | ALL(201) | ASN(201) | ALL(201) | Sexual dysfunction (SSRI/SNRI-related) | HPOID:0000078 | Abnormality of the genital system | DOID:1876 | sexual dysfunction | D020018 | Sexual Dysfunctions, Psychological | NA | NA | Testicular dysfunction | Ovarian failure | rs225848-G | Research Support, Non-U.S. Gov't | T |
14 | 48015982 | rs1160351 | A | C | rs1160351 | 22445761 | 3.00E-07 | NA | 2.92 | [1.79-4.76] | 201 Japanese ancestry individuals | Japanese(201) | ALL(201) | ASN(201) | ALL(201) | Sexual dysfunction (SSRI/SNRI-related) | HPOID:0000078 | Abnormality of the genital system | DOID:1876 | sexual dysfunction | D020018 | Sexual Dysfunctions, Psychological | NA | NA | Testicular dysfunction | Ovarian failure | rs1160351-T | Research Support, Non-U.S. Gov't | T |
14 | 98670158 | rs857228 | A | C | rs857228 | 22445761 | 3.00E-06 | NA | 2.56 | [1.60-4.08] | 201 Japanese ancestry individuals | Japanese(201) | ALL(201) | ASN(201) | ALL(201) | Sexual dysfunction (SSRI/SNRI-related) | HPOID:0000078 | Abnormality of the genital system | DOID:1876 | sexual dysfunction | D020018 | Sexual Dysfunctions, Psychological | NA | NA | Testicular dysfunction | Ovarian failure | rs857228-T | Research Support, Non-U.S. Gov't | G |
15 | 56340896 | rs7169431 | A | G | rs7169431 | 22704111 | 2.65E-05 | NA | NA | NA | 125 European ancestry Erectile dysfunction cases with Type 1 Diabetes; 403 European ancestry non Erectile dysfunction controls with Type 1 Diabetes | European(528) | ALL(528) | EUR(528) | ALL(528) | Erectile dysfunction | HPOID:0000802 | Impotence | DOID:1876 | sexual dysfunction | D007172 | Erectile Dysfunction | EFOID:0004234 | type i diabetes mellitus | Testicular dysfunction | Ovarian failure | NA | Randomized Controlled Trial | Multicenter Study |
15 | 70018990 | rs7176508 | A | G | rs7176508 | 22704111 | 2.87E-11 | NA | NA | NA | 125 European ancestry Erectile dysfunction cases with Type 1 Diabetes; 403 European ancestry non Erectile dysfunction controls with Type 1 Diabetes | European(528) | ALL(528) | EUR(528) | ALL(528) | Erectile dysfunction | HPOID:0000802 | Impotence | DOID:1876 | sexual dysfunction | D007172 | Erectile Dysfunction | EFOID:0004234 | type i diabetes mellitus | Testicular dysfunction | Ovarian failure | NA | Randomized Controlled Trial | Multicenter Study |
16 | 85944439 | rs391525 | A | G | rs391525 | 22704111 | 5.40E-07 | NA | NA | NA | 125 European ancestry Erectile dysfunction cases with Type 1 Diabetes; 403 European ancestry non Erectile dysfunction controls with Type 1 Diabetes | European(528) | ALL(528) | EUR(528) | ALL(528) | Erectile dysfunction | HPOID:0000802 | Impotence | DOID:1876 | sexual dysfunction | D007172 | Erectile Dysfunction | EFOID:0004234 | type i diabetes mellitus | Testicular dysfunction | Ovarian failure | NA | Randomized Controlled Trial | Multicenter Study |
16 | 85975659 | rs305061 | C | T | rs305061 | 22704111 | 9.42E-08 | NA | NA | NA | 125 European ancestry Erectile dysfunction cases with Type 1 Diabetes; 403 European ancestry non Erectile dysfunction controls with Type 1 Diabetes | European(528) | ALL(528) | EUR(528) | ALL(528) | Erectile dysfunction | HPOID:0000802 | Impotence | DOID:1876 | sexual dysfunction | D007172 | Erectile Dysfunction | EFOID:0004234 | type i diabetes mellitus | Testicular dysfunction | Ovarian failure | NA | Randomized Controlled Trial | Multicenter Study |
19 | 7424528 | rs6603109 | A | T | rs6603109 | 22445761 | 2.00E-06 | NA | 5.13 | [2.22-11.76] | 201 Japanese ancestry individuals | Japanese(201) | ALL(201) | ASN(201) | ALL(201) | Sexual dysfunction (SSRI/SNRI-related) | HPOID:0000078 | Abnormality of the genital system | DOID:1876 | sexual dysfunction | D020018 | Sexual Dysfunctions, Psychological | NA | NA | Testicular dysfunction | Ovarian failure | rs6603109-A | Research Support, Non-U.S. Gov't | A |
Mapped by lexical matching(Total Items:0) |
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(Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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(Waiting for update.) |
Chemical(Total Drugs:0) | |
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(Waiting for update.) |
FDA approved drug and dosage information(Total Drugs:0) | |
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(Waiting for update.) |
FDA labeling changes(Total Drugs:0) | |
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(Waiting for update.) |