PedAM
Pediatric Disease Annotations & Medicines
| sertoli-leydig cell tumor | ||||
| Disease ID | 1426 |
|---|---|
| Disease | sertoli-leydig cell tumor |
| Definition | A sex cord-gonadal stromal tumor consists of LEYDIG CELLS; SERTOLI CELLS; and FIBROBLASTS in varying proportions and degree of differentiation. Most such tumors produce ANDROGENS in the Leydig cells, formerly known as androblastoma or arrhenoblastoma. Androblastomas occur in the TESTIS or the OVARY causing precocious masculinization in the males, and defeminization, or virilization (VIRILISM) in the females. In some cases, the Sertoli cells produce ESTROGENS. |
| Synonym | cell tumor, sertoli-leydig cell tumors, sertoli-leydig sertoli leydig cell tumor sertoli leydig cell tumors sertoli-leydig cell tumor [disease/finding] sertoli-leydig cell tumors tumor, sertoli-leydig cell tumors, sertoli-leydig cell |
| DOID | |
| UMLS | C0206723 |
| MeSH | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:6) C0001418 | adenocarcinoma | 1 C0039585 | androgen insensitivity syndrome | 1 C0007130 | mucinous adenocarcinoma | 1 C0342208 | multinodular goiter | 1 C0154209 | hyperestrogenism | 1 C0018023 | nodular goiter | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:35) 6822 | SULT2A1 | DISEASES 10021 | HCN4 | DISEASES 6855 | SYP | DISEASES 10664 | CTCF | DISEASES 5443 | POMC | DISEASES 1788 | DNMT3A | DISEASES 25824 | PRDX5 | DISEASES 794 | CALB2 | DISEASES 2752 | GLUL | DISEASES 4684 | NCAM1 | DISEASES 8630 | HSD17B6 | DISEASES 3640 | INSL3 | DISEASES 5745 | PTH1R | DISEASES 5241 | PGR | DISEASES 3855 | KRT7 | DISEASES 7490 | WT1 | DISEASES 668 | FOXL2 | DISEASES 23405 | DICER1 | DISEASES 2100 | ESR2 | DISEASES 7316 | UBC | DISEASES 6146 | RPL22 | DISEASES 7080 | NKX2-1 | DISEASES 8295 | TRRAP | DISEASES 800 | CALD1 | DISEASES 1586 | CYP17A1 | DISEASES 2516 | NR5A1 | DISEASES 3293 | HSD17B3 | DISEASES 6462 | SHBG | DISEASES 1045 | CDX2 | DISEASES 2315 | MLANA | DISEASES 2254 | FGF9 | DISEASES 3875 | KRT18 | DISEASES 174 | AFP | DISEASES 54894 | RNF43 | DISEASES 7849 | PAX8 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1426 |
|---|---|
| Disease | sertoli-leydig cell tumor |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:3) |
| Disease ID | 1426 |
|---|---|
| Disease | sertoli-leydig cell tumor |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:1) C0346170 | ovarian serous cystadenoma |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
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| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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Chemical(Total Drugs:0) | |
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FDA approved drug and dosage information(Total Drugs:0) | |
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FDA labeling changes(Total Drugs:0) | |
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