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Pediatric Disease Annotations & Medicines



   sensory peripheral neuropathy
  

Disease ID 1833
Disease sensory peripheral neuropathy
Definition
functional disturbance or pathological change in the peripheral nervous system; sometimes limited to noninflammatory lesions as opposed to those of neuritis; etiology may be known or unknown.
Synonym
neuropathies sensory
peripheral neuropathy, sensory
peripheral sensory disorder
peripheral sensory neuropathy
sensory neuropathy
sensory neuropathy (disorder)
DOID
UMLS
C0151313
SNOMED-CT
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:2)
C1527336  |  sjogren syndrome  |  1
C0006142  |  breast cancer  |  1
Curated Gene(Waiting for update.)
Inferring Gene(Waiting for update.)
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:252)
2273  |  FHL1  |  DISEASES
6820  |  SULT2B1  |  DISEASES
22880  |  MORC2  |  DISEASES
84844  |  PHF5A  |  DISEASES
2287  |  FKBP3  |  DISEASES
11154  |  AP4S1  |  DISEASES
9517  |  SPTLC2  |  DISEASES
7443  |  VRK1  |  DISEASES
9352  |  TXNL1  |  DISEASES
54332  |  GDAP1  |  DISEASES
973  |  CD79A  |  DISEASES
23064  |  SETX  |  DISEASES
1440  |  CSF3  |  DISEASES
113246  |  C12orf57  |  DISEASES
59345  |  GNB4  |  DISEASES
22924  |  MAPRE3  |  DISEASES
9927  |  MFN2  |  DISEASES
7276  |  TTR  |  DISEASES
2745  |  GLRX  |  DISEASES
9419  |  CRIPT  |  DISEASES
7976  |  FZD3  |  DISEASES
10342  |  TFG  |  DISEASES
80218  |  NAA50  |  DISEASES
51426  |  POLK  |  DISEASES
4852  |  NPY  |  DISEASES
1959  |  EGR2  |  DISEASES
667  |  DST  |  DISEASES
6253  |  RTN2  |  DISEASES
2797  |  GNRH2  |  DISEASES
11034  |  DSTN  |  DISEASES
8139  |  GAN  |  DISEASES
7277  |  TUBA4A  |  DISEASES
3315  |  HSPB1  |  DISEASES
3630  |  INS  |  DISEASES
78992  |  YIPF2  |  DISEASES
6737  |  TRIM21  |  DISEASES
6754  |  SSTR4  |  DISEASES
3508  |  IGHMBP2  |  DISEASES
10717  |  AP4B1  |  DISEASES
2346  |  FOLH1  |  DISEASES
56300  |  IL36G  |  DISEASES
7274  |  TTPA  |  DISEASES
6496  |  SIX3  |  DISEASES
9585  |  KIF20B  |  DISEASES
1419  |  CRYGB  |  DISEASES
59341  |  TRPV4  |  DISEASES
55697  |  VAC14  |  DISEASES
9172  |  MYOM2  |  DISEASES
8989  |  TRPA1  |  DISEASES
10558  |  SPTLC1  |  DISEASES
5264  |  PHYH  |  DISEASES
5024  |  P2RX3  |  DISEASES
943  |  TNFRSF8  |  DISEASES
23095  |  KIF1B  |  DISEASES
55669  |  MFN1  |  DISEASES
27332  |  ZNF638  |  DISEASES
54464  |  XRN1  |  DISEASES
7879  |  RAB7A  |  DISEASES
64083  |  GOLPH3  |  DISEASES
10371  |  SEMA3A  |  DISEASES
4885  |  NPTX2  |  DISEASES
286  |  ANK1  |  DISEASES
5243  |  ABCB1  |  DISEASES
6717  |  SRI  |  DISEASES
3700  |  ITIH4  |  DISEASES
161247  |  FITM1  |  DISEASES
3073  |  HEXA  |  DISEASES
5428  |  POLG  |  DISEASES
2064  |  ERBB2  |  DISEASES
285362  |  SUMF1  |  DISEASES
2044  |  EPHA5  |  DISEASES
1956  |  EGFR  |  DISEASES
11160  |  ERLIN2  |  DISEASES
3439  |  IFNA1  |  DISEASES
6094  |  ROM1  |  DISEASES
6327  |  SCN2B  |  DISEASES
22948  |  CCT5  |  DISEASES
5805  |  PTS  |  DISEASES
291  |  SLC25A4  |  DISEASES
2043  |  EPHA4  |  DISEASES
26353  |  HSPB8  |  DISEASES
7345  |  UCHL1  |  DISEASES
4956  |  ODF1  |  DISEASES
231  |  AKR1B1  |  DISEASES
5966  |  REL  |  DISEASES
64320  |  RNF25  |  DISEASES
9497  |  SLC4A7  |  DISEASES
213  |  ALB  |  DISEASES
85477  |  SCIN  |  DISEASES
9907  |  AP5Z1  |  DISEASES
9640  |  ZNF592  |  DISEASES
762  |  CA4  |  DISEASES
4909  |  NTF4  |  DISEASES
27249  |  MMADHC  |  DISEASES
7343  |  UBTF  |  DISEASES
3479  |  IGF1  |  DISEASES
55699  |  IARS2  |  DISEASES
8988  |  HSPB3  |  DISEASES
54463  |  FAM134B  |  DISEASES
1602  |  DACH1  |  DISEASES
5990  |  RFX2  |  DISEASES
1128  |  CHRM1  |  DISEASES
23204  |  ARL6IP1  |  DISEASES
11337  |  GABARAP  |  DISEASES
3787  |  KCNS1  |  DISEASES
5376  |  PMP22  |  DISEASES
1444  |  CSHL1  |  DISEASES
3265  |  HRAS  |  DISEASES
27235  |  COQ2  |  DISEASES
1466  |  CSRP2  |  DISEASES
6712  |  SPTBN2  |  DISEASES
10645  |  CAMKK2  |  DISEASES
65125  |  WNK1  |  DISEASES
354  |  KLK3  |  DISEASES
6448  |  SGSH  |  DISEASES
6950  |  TCP1  |  DISEASES
137492  |  VPS37A  |  DISEASES
60386  |  SLC25A19  |  DISEASES
6863  |  TAC1  |  DISEASES
547  |  KIF1A  |  DISEASES
26061  |  HACL1  |  DISEASES
7525  |  YES1  |  DISEASES
3032  |  HADHB  |  DISEASES
57716  |  PRX  |  DISEASES
5663  |  PSEN1  |  DISEASES
80821  |  DDHD1  |  DISEASES
114786  |  XKR4  |  DISEASES
8303  |  SNN  |  DISEASES
6656  |  SOX1  |  DISEASES
113612  |  CYP2U1  |  DISEASES
9230  |  RAB11B  |  DISEASES
5025  |  P2RX4  |  DISEASES
10376  |  TUBA1B  |  DISEASES
55775  |  TDP1  |  DISEASES
123606  |  NIPA1  |  DISEASES
3985  |  LIMK2  |  DISEASES
9516  |  LITAF  |  DISEASES
9639  |  ARHGEF10  |  DISEASES
23394  |  ADNP  |  DISEASES
23463  |  ICMT  |  DISEASES
467  |  ATF3  |  DISEASES
3005  |  H1F0  |  DISEASES
8898  |  MTMR2  |  DISEASES
8326  |  FZD9  |  DISEASES
8650  |  NUMB  |  DISEASES
8733  |  GPAA1  |  DISEASES
120  |  ADD3  |  DISEASES
273  |  AMPH  |  DISEASES
1778  |  DYNC1H1  |  DISEASES
1996  |  ELAVL4  |  DISEASES
51062  |  ATL1  |  DISEASES
23644  |  EDC4  |  DISEASES
1995  |  ELAVL3  |  DISEASES
617  |  BCS1L  |  DISEASES
9895  |  TECPR2  |  DISEASES
1786  |  DNMT1  |  DISEASES
9179  |  AP4M1  |  DISEASES
773  |  CACNA1A  |  DISEASES
25894  |  PLEKHG4  |  DISEASES
4916  |  NTRK3  |  DISEASES
280  |  AMY2B  |  DISEASES
2705  |  GJB1  |  DISEASES
1270  |  CNTF  |  DISEASES
57165  |  GJC2  |  DISEASES
28982  |  FLVCR1  |  DISEASES
7175  |  TPR  |  DISEASES
4803  |  NGF  |  DISEASES
10492  |  SYNCRIP  |  DISEASES
6785  |  ELOVL4  |  DISEASES
4534  |  MTM1  |  DISEASES
959  |  CD40LG  |  DISEASES
1558  |  CYP2C8  |  DISEASES
6342  |  SCP2  |  DISEASES
11254  |  SLC6A14  |  DISEASES
7422  |  VEGFA  |  DISEASES
3633  |  INPP5B  |  DISEASES
6865  |  TACR2  |  DISEASES
2739  |  GLO1  |  DISEASES
6732  |  SRPK1  |  DISEASES
8518  |  IKBKAP  |  DISEASES
3339  |  HSPG2  |  DISEASES
199  |  AIF1  |  DISEASES
4795  |  NFKBIL1  |  DISEASES
1041  |  CDSN  |  DISEASES
6668  |  SP2  |  DISEASES
2395  |  FXN  |  DISEASES
6311  |  ATXN2  |  DISEASES
57449  |  PLEKHG5  |  DISEASES
643847  |  PGA4  |  DISEASES
79258  |  MMEL1  |  DISEASES
7223  |  TRPC4  |  DISEASES
54840  |  APTX  |  DISEASES
5256  |  PHKA2  |  DISEASES
1993  |  ELAVL2  |  DISEASES
7280  |  TUBB2A  |  DISEASES
23746  |  AIPL1  |  DISEASES
23464  |  GCAT  |  DISEASES
26278  |  SACS  |  DISEASES
4155  |  MBP  |  DISEASES
2617  |  GARS  |  DISEASES
285220  |  EPHA6  |  DISEASES
340152  |  ZC3H12D  |  DISEASES
9290  |  GPR55  |  DISEASES
4099  |  MAG  |  DISEASES
4287  |  ATXN3  |  DISEASES
10575  |  CCT4  |  DISEASES
27327  |  TNRC6A  |  DISEASES
128486  |  FITM2  |  DISEASES
23259  |  DDHD2  |  DISEASES
594857  |  NPS  |  DISEASES
6314  |  ATXN7  |  DISEASES
25923  |  ATL3  |  DISEASES
7442  |  TRPV1  |  DISEASES
388795  |  EFCAB8  |  DISEASES
4685  |  NCAM2  |  DISEASES
6335  |  SCN9A  |  DISEASES
56888  |  KCMF1  |  DISEASES
7852  |  CXCR4  |  DISEASES
9048  |  ARTN  |  DISEASES
146713  |  RBFOX3  |  DISEASES
121512  |  FGD4  |  DISEASES
4908  |  NTF3  |  DISEASES
7124  |  TNF  |  DISEASES
23043  |  TNIK  |  DISEASES
79718  |  TBL1XR1  |  DISEASES
221833  |  SP8  |  DISEASES
3798  |  KIF5A  |  DISEASES
7499  |  XG  |  DISEASES
3586  |  IL10  |  DISEASES
627  |  BDNF  |  DISEASES
7084  |  TK2  |  DISEASES
30816  |  ERVW-1  |  DISEASES
5447  |  POR  |  DISEASES
79628  |  SH3TC2  |  DISEASES
2110  |  ETFDH  |  DISEASES
2675  |  GFRA2  |  DISEASES
9312  |  KCNB2  |  DISEASES
4914  |  NTRK1  |  DISEASES
4359  |  MPZ  |  DISEASES
56  |  ACRV1  |  DISEASES
3748  |  KCNC3  |  DISEASES
65055  |  REEP1  |  DISEASES
11232  |  POLG2  |  DISEASES
8972  |  MGAM  |  DISEASES
10059  |  DNM1L  |  DISEASES
10381  |  TUBB3  |  DISEASES
9990  |  SLC12A6  |  DISEASES
388588  |  SMIM1  |  DISEASES
29115  |  SAP30BP  |  DISEASES
9141  |  PDCD5  |  DISEASES
25804  |  LSM4  |  DISEASES
4566  |  MT-TK  |  DISEASES
Locus(Waiting for update.)
Disease ID 1833
Disease sensory peripheral neuropathy
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:2)
HP:0012531  |  Pain  |  1
HP:0003002  |  Breast carcinoma  |  1
Disease ID 1833
Disease sensory peripheral neuropathy
Manually Symptom(Waiting for update.)
Text Mined Symptom(Waiting for update.)
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:8)
snpId pubmedId geneId geneSymbol diseaseId sourceId sentence score Year geneSymbol_dbSNP CHROMOSOME POS REF ALT
rs104894107201624372395FXNumls:C0151313BeFreeWe describe here a 41-year-old man with profound vision deficit and episodic complete blindness associated with marked optic atrophy, spastic paraparesis, and sensory neuropathy without ataxia whose diagnostic evaluation revealed compound heterozygosity for two frataxin mutations, a 994 GAA repeat intronic expansion and c.389G > T (p.G130V) missense mutation.0.0002714422010FXN969064942GC,T
rs1077197322843789121512FGD4umls:C0151313BeFreeA single nucleotide polymorphism in FGD4 was associated with the onset of sensory peripheral neuropathy in the discovery cohort [rs10771973; HR, 1.57; 95% confidence interval (CI), 1.30-1.91; P = 2.6 × 10(-6)] and in a European (HR, 1.72; 95% CI, 1.06-2.80; P = 0.013) and African American (HR, 1.93; 95% CI, 1.13-3.28; P = 6.7 × 10(-3)) replication cohort.0.0002714422012FGD41232640040GA
rs10771973228437898326FZD9umls:C0151313BeFreeThere is also evidence that markers in additional genes, including EPHA5 (rs7349683) and FZD3 (rs10771973), were associated with the onset or severity of paclitaxel-induced sensory peripheral neuropathy.0.0002714422012FGD41232640040GA
rs10771973228437892044EPHA5umls:C0151313BeFreeThere is also evidence that markers in additional genes, including EPHA5 (rs7349683) and FZD3 (rs10771973), were associated with the onset or severity of paclitaxel-induced sensory peripheral neuropathy.0.0002714422012FGD41232640040GA
rs121913602102147574359MPZumls:C0151313BeFreeWe found the association of a heterozygous novel MPZ gene point mutation, Ile62Phe in exon 2, with autosomal dominant motor and sensory neuropathy with focally folded myelin sheaths.0.0008143261999MPZ1161307308TA
rs7349683228437898326FZD9umls:C0151313BeFreeThere is also evidence that markers in additional genes, including EPHA5 (rs7349683) and FZD3 (rs10771973), were associated with the onset or severity of paclitaxel-induced sensory peripheral neuropathy.0.0002714422012EPHA5465332086CT
rs7349683228437892044EPHA5umls:C0151313BeFreeThere is also evidence that markers in additional genes, including EPHA5 (rs7349683) and FZD3 (rs10771973), were associated with the onset or severity of paclitaxel-induced sensory peripheral neuropathy.0.0002714422012EPHA5465332086CT
rs8099917237779297124TNFumls:C0151313BeFreeIL28B-rs8099917 and IL10-1082 have been associated with perturbations of the Th1/Th2 balance, whilst TNFA-1031*CC associates with sensory neuropathy in HIV patients.0.0008143262013NA1939252525TG
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:56)
CHR POS SNPID REF ALT ORI_SNPID PMID P_VALUE P_VALUE_TEXT OR/BETA CI95_TEXT GWAS_INITIAL_SAMPLE_SIZE SUB_POPULATION SUPER_POPULATION GWAS_TRAIT HPO_ID HPO_TERM DO_ID DO_TERM MESH_ID MESH_TERM EFO_ID EFO_TERM DOLITE_TERM RISK_ALLELE PUBLICATION_TYPE AA GENE_SYMBOL TYPE REFGENE
156108604rs1165472AGrs1165472237761974.00E-06NA2.36[1.64-3.40]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs1165472-GResearch Support, Non-U.S. Gov'tTNA
175458806rs12743802GArs12743802237761973.85E-05NA4.06[2.08-7.91]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs12743802-AResearch Support, Non-U.S. Gov'tGNA
1165422559rs285428TCrs285428232041300.00089NANANA77 European ancestry lymphoblastoid cell lines; 87 Yoruban lymphoblastoid cell lines; 83 African American lymphoblastoid cell linesAfrican American(83)European(77)Yoruban(87)ALL(247)AFR(170)EUR(77)ALL(247)Paclitaxel-induced cytotoxicity in lymphoblastoid cell linesHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNA
2212244403rs10932374GArs10932374237761972.58E-05NA2.25[1.54-3.28]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs10932374-AResearch Support, Non-U.S. Gov'tGERBB4
2222072178rs17348202TCrs17348202237761971.00E-06NA4.85[2.57-9.13]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs17348202-GResearch Support, Non-U.S. Gov'tTNA
335670051rs1470558TCrs1470558232041300.00077NANANA77 European ancestry lymphoblastoid cell lines; 87 Yoruban lymphoblastoid cell lines; 83 African American lymphoblastoid cell linesAfrican American(83)European(77)Yoruban(87)ALL(247)AFR(170)EUR(77)ALL(247)Paclitaxel-induced cytotoxicity in lymphoblastoid cell linesHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNA
397346618rs301927GArs301927237761973.44E-05NA2.35[1.57-3.53]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs301927-GResearch Support, Non-U.S. Gov'tGEPHA6
3187629503rs1903216AGrs1903216237761975.04E-05NA1.43[1.20-1.69]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNAResearch Support, Non-U.S. Gov'tTNA
3187839070rs189372TCrs189372237761972.98E-05NA2.27[1.55-3.35]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs189372-AResearch Support, Non-U.S. Gov'tGNA
3194329285rs7642318GTrs7642318232041300.00022NANANA77 European ancestry lymphoblastoid cell lines; 87 Yoruban lymphoblastoid cell lines; 83 African American lymphoblastoid cell linesAfrican American(83)European(77)Yoruban(87)ALL(247)AFR(170)EUR(77)ALL(247)Paclitaxel-induced cytotoxicity in lymphoblastoid cell linesHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNA
3194337708rs10933663TGrs10933663232041300.0004NANANA77 European ancestry lymphoblastoid cell lines; 87 Yoruban lymphoblastoid cell lines; 83 African American lymphoblastoid cell linesAfrican American(83)European(77)Yoruban(87)ALL(247)AFR(170)EUR(77)ALL(247)Paclitaxel-induced cytotoxicity in lymphoblastoid cell linesHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNA
466197804rs7349683CTrs7349683237761971.44E-09NA1.68[1.42-1.99]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNAResearch Support, Non-U.S. Gov'tCEPHA5
4169586731rs6846708AGrs6846708237761971.50E-05NA3.64[2.03-6.53]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs6846708-GResearch Support, Non-U.S. Gov'tAPALLD
4174438897rs7655560GArs7655560237761973.27E-05NA2.97[1.78-4.95]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs7655560-AResearch Support, Non-U.S. Gov'tGNA
56759714rs13163920CTrs13163920237761972.23E-05NA2.41[1.60-3.61]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs13163920-AResearch Support, Non-U.S. Gov'tC,TNA
56813937rs275456GTrs275456237761973.00E-06NA2.26[1.60-3.18]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs275456-AResearch Support, Non-U.S. Gov'tCNA
514393621rs10065203CTrs10065203237761974.00E-06NA2.51[1.69-3.71]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs10065203-AResearch Support, Non-U.S. Gov'tCTRIO
559620281rs6897671CTrs6897671232041300.00071NANANA77 European ancestry lymphoblastoid cell lines; 87 Yoruban lymphoblastoid cell lines; 83 African American lymphoblastoid cell linesAfrican American(83)European(77)Yoruban(87)ALL(247)AFR(170)EUR(77)ALL(247)Paclitaxel-induced cytotoxicity in lymphoblastoid cell linesHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNA
5159126775rs9313818TCrs9313818232041300.00011NANANA77 European ancestry lymphoblastoid cell lines; 87 Yoruban lymphoblastoid cell lines; 83 African American lymphoblastoid cell linesAfrican American(83)European(77)Yoruban(87)ALL(247)AFR(170)EUR(77)ALL(247)Paclitaxel-induced cytotoxicity in lymphoblastoid cell linesHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNA
5159128719rs1422857CTrs1422857232041300.00008NANANA77 European ancestry lymphoblastoid cell lines; 87 Yoruban lymphoblastoid cell lines; 83 African American lymphoblastoid cell linesAfrican American(83)European(77)Yoruban(87)ALL(247)AFR(170)EUR(77)ALL(247)Paclitaxel-induced cytotoxicity in lymphoblastoid cell linesHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNA
5170099077rs4868011ACrs4868011232041300.00082NANANA77 European ancestry lymphoblastoid cell lines; 87 Yoruban lymphoblastoid cell lines; 83 African American lymphoblastoid cell linesAfrican American(83)European(77)Yoruban(87)ALL(247)AFR(170)EUR(77)ALL(247)Paclitaxel-induced cytotoxicity in lymphoblastoid cell linesHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNA
6105630330rs1624675TA,C,Grs1624675232041300.00032NANANA77 European ancestry lymphoblastoid cell lines; 87 Yoruban lymphoblastoid cell lines; 83 African American lymphoblastoid cell linesAfrican American(83)European(77)Yoruban(87)ALL(247)AFR(170)EUR(77)ALL(247)Paclitaxel-induced cytotoxicity in lymphoblastoid cell linesHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNA
6162702534rs9365397TCrs9365397237761973.42E-05NA4.33[2.16-8.65]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs9365397-GResearch Support, Non-U.S. Gov'tTPARK2
715133127rs12699683GTrs12699683237761977.00E-06NA3.66[2.08-6.45]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs12699683-AResearch Support, Non-U.S. Gov'tTNA
7112259849rs1796502TGrs1796502232041300.00077NANANA77 European ancestry lymphoblastoid cell lines; 87 Yoruban lymphoblastoid cell lines; 83 African American lymphoblastoid cell linesAfrican American(83)European(77)Yoruban(87)ALL(247)AFR(170)EUR(77)ALL(247)Paclitaxel-induced cytotoxicity in lymphoblastoid cell linesHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNA
818381235rs10090117TCrs10090117237761974.00E-06NA2.38[1.64-3.44]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs10090117-GResearch Support, Non-U.S. Gov'tTNA
828362792rs7833751TGrs7833751228437897.50E-09NANANA855 European ancestry breast cancer casesEuropean(855)ALL(855)EUR(855)ALL(855)Paclitaxel-induced sensory peripheral neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNARandomized Controlled TrialResearch Support, N.I.H., ExtramuralT
828363378rs7001034AGrs7001034228437893.10E-09NANANA855 European ancestry breast cancer casesEuropean(855)ALL(855)EUR(855)ALL(855)Paclitaxel-induced sensory peripheral neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNARandomized Controlled TrialResearch Support, N.I.H., ExtramuralG
848483958rs6473187GArs6473187237761972.17E-05NA3.37[1.92-5.91]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs6473187-GResearch Support, Non-U.S. Gov'tAKIAA0146
856111322rs4737264ACrs4737264237761973.11E-08NA1.71[1.41-2.06]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNAResearch Support, Non-U.S. Gov'tAXKR4
8106283030rs2941627GArs2941627228437890.0000035NANANA855 European ancestry breast cancer casesEuropean(855)ALL(855)EUR(855)ALL(855)Paclitaxel-induced sensory peripheral neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNARandomized Controlled TrialResearch Support, N.I.H., ExtramuralT
94039727rs501461GTrs501461237761971.24E-05NA2.33[1.59-3.45]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs501461-AResearch Support, Non-U.S. Gov'tTGLIS3
9111455575rs10512385AGrs10512385237761976.00E-06NA2.58[1.71-3.89]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs10512385-GResearch Support, Non-U.S. Gov'tANA
1018476276rs16916932CTrs16916932237761978.40E-06NA1.93[1.44-2.58]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNAResearch Support, Non-U.S. Gov'tCCACNB2
1136540549rs331455CTrs331455232041300.00048NANANA77 European ancestry lymphoblastoid cell lines; 87 Yoruban lymphoblastoid cell lines; 83 African American lymphoblastoid cell linesAfrican American(83)European(77)Yoruban(87)ALL(247)AFR(170)EUR(77)ALL(247)Paclitaxel-induced cytotoxicity in lymphoblastoid cell linesHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNA
11133897382rs724095AGrs724095232041300.00034NANANA77 European ancestry lymphoblastoid cell lines; 87 Yoruban lymphoblastoid cell lines; 83 African American lymphoblastoid cell linesAfrican American(83)European(77)Yoruban(87)ALL(247)AFR(170)EUR(77)ALL(247)Paclitaxel-induced cytotoxicity in lymphoblastoid cell linesHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNA
126308523rs3181157CTrs3181157237761974.00E-06NA3.22[1.96-5.29]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs3181157-AResearch Support, Non-U.S. Gov'tT,CNA
1221292280rs3829306CTrs3829306237761972.84E-05NA3.1[1.82-5.26]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs3829306-AResearch Support, Non-U.S. Gov'tGSLCO1B1
1224917962rs7973533TGrs7973533228437890.0000084NANANA855 European ancestry breast cancer casesEuropean(855)ALL(855)EUR(855)ALL(855)Paclitaxel-induced sensory peripheral neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNARandomized Controlled TrialResearch Support, N.I.H., ExtramuralT
1232792974rs10771973GArs10771973237761972.77E-06NA1.53[1.28-1.82]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNAResearch Support, Non-U.S. Gov'tGFGD4
1267476327rs17781082CTrs17781082237761975.52E-06NA1.5[1.26-1.78]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNAResearch Support, Non-U.S. Gov'tCNA
12103761292rs11111539GArs11111539232041300.00079NANANA77 European ancestry lymphoblastoid cell lines; 87 Yoruban lymphoblastoid cell lines; 83 African American lymphoblastoid cell linesAfrican American(83)European(77)Yoruban(87)ALL(247)AFR(170)EUR(77)ALL(247)Paclitaxel-induced cytotoxicity in lymphoblastoid cell linesHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNA
12103771416rs7306825TGrs7306825232041300.00072NANANA77 European ancestry lymphoblastoid cell lines; 87 Yoruban lymphoblastoid cell lines; 83 African American lymphoblastoid cell linesAfrican American(83)European(77)Yoruban(87)ALL(247)AFR(170)EUR(77)ALL(247)Paclitaxel-induced cytotoxicity in lymphoblastoid cell linesHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNA
1323878686rs1753097GArs1753097237761971.96E-05NA2.18[1.52-3.11]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs1753097-GResearch Support, Non-U.S. Gov'tASGCG
1536049492rs2947253GArs2947253237761974.00E-06NA3.38[2.01-5.68]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs2947253-GResearch Support, Non-U.S. Gov'tALOC100507466
1617408872rs4782010CTrs4782010232041300.00055NANANA77 European ancestry lymphoblastoid cell lines; 87 Yoruban lymphoblastoid cell lines; 83 African American lymphoblastoid cell linesAfrican American(83)European(77)Yoruban(87)ALL(247)AFR(170)EUR(77)ALL(247)Paclitaxel-induced cytotoxicity in lymphoblastoid cell linesHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNA
171457839rs16948748TGrs16948748237761971.95E-06NA2.34[1.65-3.32]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNAResearch Support, Non-U.S. Gov'tTPITPNA
1712887379rs8069856TCrs8069856232041300.00011NANANA77 European ancestry lymphoblastoid cell lines; 87 Yoruban lymphoblastoid cell lines; 83 African American lymphoblastoid cell linesAfrican American(83)European(77)Yoruban(87)ALL(247)AFR(170)EUR(77)ALL(247)Paclitaxel-induced cytotoxicity in lymphoblastoid cell linesHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNA
1834735899rs323285TCrs323285232041300.00051NANANA77 European ancestry lymphoblastoid cell lines; 87 Yoruban lymphoblastoid cell lines; 83 African American lymphoblastoid cell linesAfrican American(83)European(77)Yoruban(87)ALL(247)AFR(170)EUR(77)ALL(247)Paclitaxel-induced cytotoxicity in lymphoblastoid cell linesHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNA
19756985rs8110536TGrs8110536237761972.98E-05NA2.24[1.53-3.27]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs8110536-CResearch Support, Non-U.S. Gov'tGC19orf21
196028227rs7254081CArs7254081232041300.00059NANANA77 European ancestry lymphoblastoid cell lines; 87 Yoruban lymphoblastoid cell lines; 83 African American lymphoblastoid cell linesAfrican American(83)European(77)Yoruban(87)ALL(247)AFR(170)EUR(77)ALL(247)Paclitaxel-induced cytotoxicity in lymphoblastoid cell linesHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNA
1916153445rs10403813GArs10403813232041300.00063NANANA77 European ancestry lymphoblastoid cell lines; 87 Yoruban lymphoblastoid cell lines; 83 African American lymphoblastoid cell linesAfrican American(83)European(77)Yoruban(87)ALL(247)AFR(170)EUR(77)ALL(247)Paclitaxel-induced cytotoxicity in lymphoblastoid cell linesHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNA
2041670237rs2425553CTrs2425553237761971.94E-05NA2.33[1.58-3.44]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs2425553-AResearch Support, Non-U.S. Gov'tCPTPRT
2231665862rs2413045AGrs2413045237761973.67E-05NA2.36[1.57-3.56]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs2413045-AResearch Support, Non-U.S. Gov'tGLIMK2
2231675185rs4141404ACrs4141404237761973.00E-06NA2.41[1.66-3.48]143 European ancestry individualsEuropean(143)ALL(143)EUR(143)ALL(143)Paclitaxel-induced neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyrs4141404-AResearch Support, Non-U.S. Gov'tGLIMK2
X9751474rs5934683TCrs5934683228437890.0000006NANANA855 European ancestry breast cancer casesEuropean(855)ALL(855)EUR(855)ALL(855)Paclitaxel-induced sensory peripheral neuropathyHPOID:0000763Sensory neuropathyDOID:2491sensory peripheral neuropathyNANANANANeuropathyNARandomized Controlled TrialResearch Support, N.I.H., ExtramuralT
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