PedAM

Pediatric Disease Annotations & Medicines


	scabies

Disease ID	1257
Disease	scabies
Definition	A contagious cutaneous inflammation caused by the bite of the mite SARCOPTES SCABIEI. It is characterized by pruritic papular eruptions and burrows and affects primarily the axillae, elbows, wrists, and genitalia, although it can spread to cover the entire body.
Synonym	infestation by sarcoptes scabiei infestation by sarcoptes scabiei (disorder) infestation by sarcoptes scabiei var hominis infestation by sarcoptes scabiei var hominis (disorder) infestation caused by sarcoptes scabiei var hominis infestation caused by sarcoptes scabiei var hominis (disorder) sarcoptic itch scabies scabies [disease/finding]
DOID	DOID:8295
ICD10	ICD10CM:B86
UMLS	C0036262
MeSH	D012532
SNOMED-CT	SNOMEDCT_US_2016_09_01:128869009
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:15) C0004623 \| bacterial infection \| 4 C0037280 \| infestation \| 3 C0022658 \| kidney disease \| 2 C0004623 \| bacterial infections \| 2 C0021099 \| impetigo \| 1 C0034212 \| pyoderma \| 1 C0002989 \| angiolymphoid hyperplasia with eosinophilia \| 1 C0032285 \| pneumonitis \| 1 C0003864 \| arthritis \| 1 C0002989 \| angiolymphoid hyperplasia \| 1 C0019158 \| hepatitis \| 1 C0003873 \| rheumatoid arthritis \| 1 C0001175 \| acquired immunodeficiency syndrome \| 1 C0024899 \| mastocytosis \| 1 C0011603 \| dermatitis \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:37) 49 \| ACR \| DISEASES 973 \| CD79A \| DISEASES 50813 \| COPS7A \| DISEASES 3567 \| IL5 \| DISEASES 7043 \| TGFB3 \| DISEASES 7291 \| TWIST1 \| DISEASES 30833 \| NT5C \| DISEASES 1830 \| DSG3 \| DISEASES 1828 \| DSG1 \| DISEASES 4092 \| SMAD7 \| DISEASES 943 \| TNFRSF8 \| DISEASES 2208 \| FCER2 \| DISEASES 51726 \| DNAJB11 \| DISEASES 213 \| ALB \| DISEASES 1230 \| CCR1 \| DISEASES 6240 \| RRM1 \| DISEASES 8832 \| CD84 \| DISEASES 5178 \| PEG3 \| DISEASES 342510 \| CD300E \| DISEASES 4088 \| SMAD3 \| DISEASES 3753 \| KCNE1 \| DISEASES 63826 \| SRR \| DISEASES 7080 \| NKX2-1 \| DISEASES 5169 \| ENPP3 \| DISEASES 51592 \| TRIM33 \| DISEASES 126767 \| AADACL3 \| DISEASES 1825 \| DSC3 \| DISEASES 4512 \| MT-CO1 \| DISEASES 7052 \| TGM2 \| DISEASES 2312 \| FLG \| DISEASES 2316 \| FLNA \| DISEASES 959 \| CD40LG \| DISEASES 3376 \| IARS \| DISEASES 3776 \| KCNK2 \| DISEASES 387836 \| CLEC2A \| DISEASES 488 \| ATP2A2 \| DISEASES 246744 \| STH \| DISEASES
Locus	(Waiting for update.)

Disease ID	1257
Disease	scabies
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:13) HP:0000989 \| pruritis \| 2 HP:0100495 \| Mastocytosis \| 1 HP:0001019 \| Exfoliative dermititis \| 1 HP:0001370 \| Rheumatoid arthritis \| 1 HP:0001369 \| Arthritis \| 1 HP:0000999 \| Pyoderma \| 1 HP:0001581 \| Recurrent skin infections \| 1 HP:0200034 \| Papule \| 1 HP:0002721 \| Immunodeficiency \| 1 HP:0002240 \| Enlarged liver \| 1 HP:0001880 \| Eosinophilia \| 1 HP:0030350 \| Erythematous papule \| 1 HP:0012115 \| Liver inflammation \| 1

Disease ID	1257
Disease	scabies
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:6) C0037280 \| infestation \| 3 C0021311 \| infections \| 3 C0004623 \| bacterial infections \| 2 C0033774 \| pruritus \| 2 C0014457 \| eosinophilia \| 1 C0004623 \| bacterial infection \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:1)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0036262	lindane	D001556	58-89-9	scabies	MESH:D012532	therapeutic	1707072

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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