sarcoma, synovial |
Disease ID | 1086 |
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Disease | sarcoma, synovial |
Definition | A malignant neoplasm arising from tenosynovial tissue of the joints and in synovial cells of tendons and bursae. The legs are the most common site, but the tumor can occur in the abdominal wall and other trunk muscles. There are two recognized types: the monophasic (characterized by sheaths of monotonous spindle cells) and the biphasic (characterized by slit-like spaces or clefts within the tumor, lined by cuboidal or tall columnar epithelial cells). These sarcomas occur most commonly in the second and fourth decades of life. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1363) |
Synonym | [m]synovial sarcoma nos [m]synovioma nos malignant synovioma sarcoma synovial sarcoma, synovial [disease/finding] sarcoma, synovial, malignant sarcomas, synovial ss synovial sarcoma synovial sarcoma (disorder) synovial sarcoma (morphologic abnormality) synovial sarcoma, nos synovial sarcoma, not otherwise specified synovial sarcomas synovioma synovioma, malignant synovioma, nos synoviomas |
Orphanet | |
OMIM | |
DOID | |
UMLS | C0039101 |
MeSH | |
SNOMED-CT | |
Curated Gene | Entrez_id | Symbol | Resource(Total Genes:5) |
Inferring Gene | (Waiting for update.) |
Text Mined Gene | (Waiting for update.) |
Locus | (Waiting for update.) |
Disease ID | 1086 |
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Disease | sarcoma, synovial |
Integrated Phenotype | HPO | Name(Total Integrated Phenotypes:1) HP:0012570 | Synovial sarcoma |
Text Mined Phenotype | (Waiting for update.) |
Disease ID | 1086 |
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Disease | sarcoma, synovial |
Manually Symptom | (Waiting for update.) |
Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
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All Snps(Total Genotypes:0) | |
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GWASdb Annotation(Total Genotypes:0) | |
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GWASdb Snp Trait(Total Genotypes:0) | |
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Mapped by lexical matching(Total Items:0) |
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Mapped by homologous gene(Total Items:0) |
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Chemical(Total Drugs:4) | |||||||||
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CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
C0039101 | cisplatin | D002945 | 15663-27-1 | sarcoma, synovial | MESH:D013584 | therapeutic | 2206854 | ||
C0039101 | ifosfamide | D007069 | 3778-73-2 | sarcoma, synovial | MESH:D013584 | therapeutic | 7668875 | ||
C0039101 | streptozocin | D013311 | 18883-66-4 | sarcoma, synovial | MESH:D013584 | therapeutic | 4261143 | ||
C0039101 | vincristine | D014750 | - | sarcoma, synovial | MESH:D013584 | therapeutic | 7668875 |
FDA approved drug and dosage information(Total Drugs:0) | |
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FDA labeling changes(Total Drugs:0) | |
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