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PedAM

Pediatric Disease Annotations & Medicines



   sarcoma, synovial
  

Disease ID 1086
Disease sarcoma, synovial
Definition
A malignant neoplasm arising from tenosynovial tissue of the joints and in synovial cells of tendons and bursae. The legs are the most common site, but the tumor can occur in the abdominal wall and other trunk muscles. There are two recognized types: the monophasic (characterized by sheaths of monotonous spindle cells) and the biphasic (characterized by slit-like spaces or clefts within the tumor, lined by cuboidal or tall columnar epithelial cells). These sarcomas occur most commonly in the second and fourth decades of life. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1363)
Synonym
[m]synovial sarcoma nos
[m]synovioma nos
malignant synovioma
sarcoma synovial
sarcoma, synovial [disease/finding]
sarcoma, synovial, malignant
sarcomas, synovial
ss
synovial sarcoma
synovial sarcoma (disorder)
synovial sarcoma (morphologic abnormality)
synovial sarcoma, nos
synovial sarcoma, not otherwise specified
synovial sarcomas
synovioma
synovioma, malignant
synovioma, nos
synoviomas
Orphanet
OMIM
DOID
UMLS
C0039101
MeSH
SNOMED-CT
Curated Gene
Entrez_id | Symbol | Resource(Total Genes:5)
BCL2  |  596  |  CTD_human
VIM  |  7431  |  CTD_human
SSX1  |  6756  |  CTD_human;ORPHANET
SSX2  |  6757  |  CTD_human;ORPHANET
SS18  |  6760  |  CTD_human;ORPHANET
Inferring Gene(Waiting for update.)
Text Mined Gene(Waiting for update.)
Locus(Waiting for update.)
Disease ID 1086
Disease sarcoma, synovial
Integrated Phenotype
HPO | Name(Total Integrated Phenotypes:1)
HP:0012570  |  Synovial sarcoma
Text Mined Phenotype(Waiting for update.)
Disease ID 1086
Disease sarcoma, synovial
Manually Symptom(Waiting for update.)
Text Mined Symptom(Waiting for update.)
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:0)
(Waiting for update.)
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)
Mapped by lexical matching(Total Items:0)
(Waiting for update.)
Mapped by homologous gene(Total Items:0)
(Waiting for update.)
Chemical(Total Drugs:4)
CUI ChemicalName ChemicalID CasRN DiseaseName DiseaseID DirectEvidence PubMedIDs
C0039101cisplatinD00294515663-27-1sarcoma, synovialMESH:D013584therapeutic2206854
C0039101ifosfamideD0070693778-73-2sarcoma, synovialMESH:D013584therapeutic7668875
C0039101streptozocinD01331118883-66-4sarcoma, synovialMESH:D013584therapeutic4261143
C0039101vincristineD014750-sarcoma, synovialMESH:D013584therapeutic7668875
FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)
FDA labeling changes(Total Drugs:0)
(Waiting for update.)