PedAM

Pediatric Disease Annotations & Medicines


	sarcoma

Disease ID	529
Disease	sarcoma
Definition	A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.
Synonym	[m]sarcoma nos [m]sarcoma nos (morphologic abnormality) cancer of the soft tissue connective tissue sarcoma malignant mesenchymal tumour malignant neoplasm of soft tissue malignant neoplasm of soft tissue (disorder) malignant neoplasm of soft tissues malignant neoplasm of the soft tissue malignant soft tissue neoplasm malignant soft tissue tumor malignant soft tissue tumors malignant tumor of soft tissue malignant tumor of soft tissue (disorder) malignant tumor of the soft tissue malignant tumour of soft tissue mesenchymal malignant tumor mesenchymal tumor, malignant mesenchymal tumour, malignant non-rhabdo. soft tissue sarcoma non-rhabdomyosarcoma soft tissue sarcoma, nos sarcoma (disorder) sarcoma [disease/finding] sarcoma nos sarcoma of soft tissue sarcoma of soft tissue (disorder) sarcoma of soft tissue and bone sarcoma of the soft tissue sarcoma of the soft tissue and bone sarcoma soft tissue sarcoma, malignant sarcoma, no icd-o subtype sarcoma, no icd-o subtype (morphologic abnormality) sarcoma, no international classification of diseases for oncology subtype sarcoma, no international classification of diseases for oncology subtype (morphologic abnormality) sarcoma, nos sarcoma, soft tissue sarcomas sarcomas soft tissue sarcomas, soft tissue soft tissue sarcoma soft tissue sarcomas soft tissue tumor, malignant soft tissue tumour, malignant
Orphanet	ORPHANET:3394
DOID	DOID:1115
UMLS	C1261473
MeSH	D012509
SNOMED-CT	SNOMEDCT_US_2016_09_01:269469005;SNOMEDCT_US_2016_09_01:424413001;SNOMEDCT_US_2016_09_01:424952003
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:219) C0023418 \| leukemia \| 17 C0023827 \| liposarcoma \| 12 C0024299 \| lymphoma \| 12 C0023467 \| acute myeloid leukemia \| 10 C1261473 \| sarcoma \| 10 C1261473 \| sarcomas \| 10 C0023470 \| myeloid leukemia \| 10 C0334463 \| malignant fibrous histiocytoma \| 9 C0206644 \| fibrous histiocytoma \| 9 C1509147 \| histiocytoma \| 8 C0035412 \| rhabdomyosarcoma \| 8 C0553580 \| ewing sarcoma \| 6 C0153676 \| lung metastasis \| 6 C0153676 \| lung metastases \| 5 C0025202 \| melanoma \| 5 C0001175 \| acquired immunodeficiency syndrome \| 5 C0206093 \| primitive neuroectodermal tumor \| 4 C0029463 \| osteosarcoma \| 4 C0279980 \| extraskeletal ewing's sarcoma \| 4 C1334699 \| mesenchymal tumor \| 4 C0001418 \| adenocarcinoma \| 4 C0030807 \| pemphigus \| 4 C0024299 \| lymphomas \| 4 C0030809 \| pemphigus vulgaris \| 3 C0019829 \| hodgkin lymphoma \| 3 C0023470 \| myelocytic leukemia \| 3 C0007137 \| squamous cell carcinoma \| 3 C0027819 \| neuroblastoma \| 3 C0023443 \| hairy cell leukemia \| 3 C0023269 \| leiomyosarcoma \| 3 C0026896 \| myasthenia gravis \| 3 C0003864 \| arthritis \| 3 C0024305 \| non-hodgkin lymphoma \| 3 C0023487 \| promyelocytic leukemia \| 3 C0023487 \| acute promyelocytic leukemia \| 3 C0085113 \| neurofibromatosis \| 3 C0153676 \| pulmonary metastases \| 3 C0238301 \| nasopharyngeal carcinoma \| 2 C0001418 \| adenocarcinomas \| 2 C0027947 \| neutropenia \| 2 C0024314 \| lymphoproliferative disorder \| 2 C0017658 \| glomerulonephritis \| 2 C0039101 \| synovial sarcoma \| 2 C0011570 \| depression \| 2 C0033860 \| psoriasis \| 2 C0035078 \| renal failure \| 2 C0007137 \| squamous carcinoma \| 2 C0259779 \| fibrous dysplasia \| 2 C0220650 \| brain metastasis \| 2 C0016057 \| fibrosarcoma \| 2 C0025202 \| malignant melanoma \| 2 C0024205 \| lymphadenitis \| 2 C0023434 \| lymphocytic lymphoma \| 2 C0080032 \| malignant pleural effusion \| 2 C0018922 \| hemangiopericytoma \| 2 C0014175 \| endometriosis \| 2 C0027708 \| wilms' tumor \| 2 C0017525 \| giant cell tumor \| 2 C0024314 \| lymphoproliferative disorders \| 2 C0010631 \| cystadenocarcinoma \| 2 C0751690 \| malignant peripheral nerve sheath tumor \| 2 C0017665 \| membranous glomerulonephritis \| 2 C0879615 \| stromal tumor \| 2 C0023470 \| myeloid leukaemia \| 2 C0032326 \| pneumothorax \| 2 C0153676 \| pulmonary metastasis \| 2 C0035412 \| rhabdomyosarcomas \| 2 C0023269 \| leiomyosarcomas \| 2 C0023418 \| leukaemia \| 2 C0598894 \| monocytic leukemia \| 2 C0023267 \| leiomyoma \| 2 C0018916 \| hemangiomas \| 2 C0019204 \| hepatocellular carcinoma \| 2 C0023473 \| chronic myeloid leukaemia \| 2 C0007115 \| thyroid ca \| 2 C0206630 \| endometrial stromal sarcoma \| 2 C0026986 \| myelodysplastic syndrome \| 2 C0030326 \| panniculitis \| 2 C0085669 \| acute leukemia \| 2 C0686619 \| lymph node metastases \| 2 C0023470 \| myelogenous leukemia \| 2 C0023473 \| chronic myelogenous leukemia \| 2 C0238198 \| gastrointestinal stromal tumor \| 2 C0014733 \| erysipelas \| 2 C0016045 \| fibroma \| 2 C0281508 \| desmoplastic small round cell tumor \| 1 C0024301 \| follicular lymphoma \| 1 C0012739 \| disseminated intravascular coagulation \| 1 C0023449 \| acute lymphoblastic leukemia \| 1 C1334699 \| mesenchymal neoplasm \| 1 C0149782 \| squamous cell carcinoma of the lung \| 1 C0155773 \| portal vein thrombosis \| 1 C0349604 \| intracranial meningioma \| 1 C0023467 \| acute myeloblastic leukemia \| 1 C1153706 \| adenocarcinoma of the uterus \| 1 C0023465 \| acute monocytic leukemia \| 1 C0040053 \| thrombosis \| 1 C0040558 \| toxoplasmosis \| 1 C0007137 \| squamous cell carcinomas \| 1 C0027809 \| schwannoma \| 1 C0002871 \| anemia \| 1 C0030805 \| bullous pemphigoid \| 1 C0040034 \| thrombocytopenia \| 1 C0023473 \| chronic myeloid leukemia \| 1 C0037274 \| dermatological disorder \| 1 C0027022 \| myeloid malignancy \| 1 C0854906 \| benign schwannoma \| 1 C0238463 \| papillary thyroid carcinoma \| 1 C0007102 \| colon cancer \| 1 C0033680 \| protein-losing enteropathy \| 1 C0000889 \| acanthosis nigricans \| 1 C1261473 \| soft tissue sarcoma \| 1 C0278586 \| metastatic ewing's sarcoma \| 1 C0220650 \| brain metastases \| 1 C1333971 \| mesenchymal hamartoma of the liver \| 1 C0003873 \| rheumatoid arthritis \| 1 C0010633 \| cystadenoma \| 1 C0023890 \| cirrhosis \| 1 C0027858 \| neuroma \| 1 C0009324 \| ulcerative colitis \| 1 C0017636 \| glioblastoma \| 1 C0178879 \| urinary obstruction \| 1 C0019348 \| herpes simplex \| 1 C0270736 \| essential tremor \| 1 C0751967 \| relapsing-remitting multiple sclerosis \| 1 C0023448 \| lymphoblastic leukemia \| 1 C0494165 \| liver metastases \| 1 C0206701 \| serous carcinoma \| 1 C0026769 \| multiple sclerosis \| 1 C0008479 \| chondrosarcomas \| 1 C0025286 \| meningiomas \| 1 C0042900 \| vitiligo \| 1 C0008625 \| chromosomal abnormality \| 1 C0024314 \| lymphoproliferative disease \| 1 C0221406 \| cushing disease \| 1 C0001175 \| acquired immune deficiency syndrome \| 1 C0341858 \| adenomyosis \| 1 C0043117 \| idiopathic thrombocytopenia \| 1 C0041296 \| tuberculosis \| 1 C0016057 \| fibrosarcomas \| 1 C0042373 \| vascular diseases \| 1 C0027830 \| neurofibroma \| 1 C0022354 \| obstructive jaundice \| 1 C0026393 \| molluscum contagiosum \| 1 C1368910 \| mature teratoma \| 1 C0494165 \| liver metastasis \| 1 C0079419 \| li-fraumeni syndrome \| 1 C0494165 \| hepatic metastases \| 1 C0024291 \| hemophagocytic syndrome \| 1 C0003615 \| appendicitis \| 1 C0007847 \| cervical cancer \| 1 C0011615 \| atopic dermatitis \| 1 C0334634 \| mantle cell lymphoma \| 1 C0009319 \| colitis \| 1 C0007140 \| carcinosarcoma \| 1 C0042373 \| vascular disease \| 1 C0018801 \| heart failure \| 1 C0027122 \| myositis ossificans \| 1 C0206702 \| klatskin tumor \| 1 C0018213 \| graves disease \| 1 C0023434 \| small lymphocytic lymphoma \| 1 C0029443 \| osteomyelitis \| 1 C0027022 \| myeloproliferative neoplasms \| 1 C0392548 \| cauda equina syndrome \| 1 C0018802 \| congestive heart failure \| 1 C1328840 \| autoimmune lymphoproliferative syndrome \| 1 C1334811 \| mucinous tumor \| 1 C1335437 \| plexopathy \| 1 C0280856 \| vulvar squamous cell carcinoma \| 1 C0007113 \| rectal cancer \| 1 C0334517 \| spermatocytic seminoma \| 1 C0553580 \| ewing's sarcoma \| 1 C0022661 \| chronic renal failure \| 1 C0023267 \| fibroids \| 1 C0036631 \| seminoma \| 1 C0014742 \| erythema multiforme \| 1 C0040261 \| onychomycosis \| 1 C0029925 \| carcinoma of ovary \| 1 C0279530 \| bone cancer \| 1 C0010635 \| mucinous cystadenoma \| 1 C0011633 \| dermatomyositis \| 1 C0021831 \| enteropathy \| 1 C0021843 \| bowel obstruction \| 1 C0205696 \| anaplastic carcinoma \| 1 C0023827 \| liposarcomas \| 1 C0030486 \| paraplegia \| 1 C0700251 \| brachial plexopathy \| 1 C0001175 \| acquired immune deficiency \| 1 C0039538 \| teratomas \| 1 C0018206 \| granulosa cell tumors \| 1 C0024299 \| malignant lymphoma \| 1 C0152025 \| polyneuropathy \| 1 C0023267 \| fibroid \| 1 C0376358 \| prostate cancer \| 1 C0023470 \| myelogenous leukaemia \| 1 C0235974 \| pancreatic cancer \| 1 C0042133 \| uterine leiomyoma \| 1 C0206623 \| adenosquamous carcinoma \| 1 C0027121 \| myositis \| 1 C0002871 \| anaemia \| 1 C0022658 \| renal disease \| 1 C0005684 \| bladder cancer \| 1 C0549473 \| thyroid carcinoma \| 1 C0948303 \| peritoneal carcinoma \| 1 C0029456 \| osteoporosis \| 1 C0040028 \| essential thrombocythemia \| 1 C0024115 \| pulmonary disease \| 1 C0302592 \| cervical ca \| 1 C0004134 \| ataxia \| 1 C0006142 \| breast cancer \| 1 C0001430 \| adenoma \| 1 C0011603 \| dermatitis \| 1 C0023895 \| hepatic disease \| 1 C0018206 \| granulosa cell tumor \| 1 C0349604 \| intracranial meningiomas \| 1 C0238198 \| gastrointestinal stromal tumor (gist) \| 1 C0042133 \| uterine fibroid \| 1 C0206699 \| mucinous cystadenocarcinoma \| 1 C0836924 \| thrombocythemia \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:13) TNF \| 7124 \| CTD_human MCL1 \| 4170 \| CTD_human PIK3CA \| 5290 \| CLINVAR;CTD_human TP53 \| 7157 \| CLINVAR;CTD_human PRAME \| 23532 \| CTD_human IFNG \| 3458 \| CTD_human NF1 \| 4763 \| CTD_human CSF2 \| 1437 \| CTD_human SMARCA4 \| 6597 \| CTD_human GSTP1 \| 2950 \| CTD_human SOX2 \| 6657 \| CTD_human PAX3 \| 5077 \| CTD_human MAML3 \| 55534 \| CTD_human
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:11) 2068 \| ERCC2 \| infer 2073 \| ERCC5 \| infer 3265 \| HRAS \| infer 3845 \| KRAS \| infer 4893 \| NRAS \| infer 7157 \| TP53 \| infer 2944 \| GSTM1 \| infer 2952 \| GSTT1 \| infer 7515 \| XRCC1 \| infer 7516 \| XRCC2 \| infer 7517 \| XRCC3 \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:722) 100874322 \| BACH1-IT2 \| DISEASES 4830 \| NME1 \| DISEASES 1015 \| CDH17 \| DISEASES 84699 \| CREB3L3 \| DISEASES 7132 \| TNFRSF1A \| DISEASES 54474 \| KRT20 \| DISEASES 4804 \| NGFR \| DISEASES 2099 \| ESR1 \| DISEASES 7414 \| VCL \| DISEASES 7049 \| TGFBR3 \| DISEASES 10291 \| SF3A1 \| DISEASES 5594 \| MAPK1 \| DISEASES 7380 \| UPK3A \| DISEASES 3002 \| GZMB \| DISEASES 1113 \| CHGA \| DISEASES 6790 \| AURKA \| DISEASES 57167 \| SALL4 \| DISEASES 6725 \| SRMS \| DISEASES 54941 \| RNF125 \| DISEASES 10735 \| STAG2 \| DISEASES 54 \| ACP5 \| DISEASES 4313 \| MMP2 \| DISEASES 10423 \| CDIPT \| DISEASES 7038 \| TG \| DISEASES 8797 \| TNFRSF10A \| DISEASES 27294 \| DHDH \| DISEASES 10535 \| RNASEH2A \| DISEASES 268 \| AMH \| DISEASES 973 \| CD79A \| DISEASES 1048 \| CEACAM5 \| DISEASES 3082 \| HGF \| DISEASES 51510 \| CHMP5 \| DISEASES 7431 \| VIM \| DISEASES 4353 \| MPO \| DISEASES 1440 \| CSF3 \| DISEASES 6198 \| RPS6KB1 \| DISEASES 6347 \| CCL2 \| DISEASES 1277 \| COL1A1 \| DISEASES 7448 \| VTN \| DISEASES 3558 \| IL2 \| DISEASES 595 \| CCND1 \| DISEASES 4254 \| KITLG \| DISEASES 4618 \| MYF6 \| DISEASES 4617 \| MYF5 \| DISEASES 2735 \| GLI1 \| DISEASES 3458 \| IFNG \| DISEASES 11103 \| KRR1 \| DISEASES 2597 \| GAPDH \| DISEASES 2026 \| ENO2 \| DISEASES 79923 \| NANOG \| DISEASES 55907 \| CMAS \| DISEASES 3910 \| LAMA4 \| DISEASES 1839 \| HBEGF \| DISEASES 4015 \| LOX \| DISEASES 6678 \| SPARC \| DISEASES 3593 \| IL12B \| DISEASES 3565 \| IL4 \| DISEASES 4292 \| MLH1 \| DISEASES 604 \| BCL6 \| DISEASES 4436 \| MSH2 \| DISEASES 84141 \| EVA1A \| DISEASES 3485 \| IGFBP2 \| DISEASES 3398 \| ID2 \| DISEASES 4953 \| ODC1 \| DISEASES 2956 \| MSH6 \| DISEASES 112752 \| IFT43 \| DISEASES 8600 \| TNFSF11 \| DISEASES 10342 \| TFG \| DISEASES 10804 \| GJB6 \| DISEASES 8743 \| TNFSF10 \| DISEASES 2322 \| FLT3 \| DISEASES 4656 \| MYOG \| DISEASES 5552 \| SRGN \| DISEASES 1026 \| CDKN1A \| DISEASES 6662 \| SOX9 \| DISEASES 8744 \| TNFSF9 \| DISEASES 57187 \| THOC2 \| DISEASES 79414 \| LRFN3 \| DISEASES 2123 \| EVI2A \| DISEASES 8089 \| YEATS4 \| DISEASES 5300 \| PIN1 \| DISEASES 3315 \| HSPB1 \| DISEASES 51657 \| STYXL1 \| DISEASES 65997 \| RASL11B \| DISEASES 7533 \| YWHAH \| DISEASES 22933 \| SIRT2 \| DISEASES 4654 \| MYOD1 \| DISEASES 54478 \| FAM64A \| DISEASES 9098 \| USP6 \| DISEASES 968 \| CD68 \| DISEASES 83855 \| KLF16 \| DISEASES 3630 \| INS \| DISEASES 6217 \| RPS16 \| DISEASES 5894 \| RAF1 \| DISEASES 10389 \| SCML2 \| DISEASES 3852 \| KRT5 \| DISEASES 9667 \| SAFB2 \| DISEASES 10439 \| OLFM1 \| DISEASES 9253 \| NUMBL \| DISEASES 9113 \| LATS1 \| DISEASES 2670 \| GFAP \| DISEASES 9476 \| NAPSA \| DISEASES 2538 \| G6PC \| DISEASES 3866 \| KRT15 \| DISEASES 2521 \| FUS \| DISEASES 22856 \| CHSY1 \| DISEASES 6382 \| SDC1 \| DISEASES 3021 \| H3F3B \| DISEASES 29107 \| NXT1 \| DISEASES 1401 \| CRP \| DISEASES 3845 \| KRAS \| DISEASES 10894 \| LYVE1 \| DISEASES 8553 \| BHLHE40 \| DISEASES 10752 \| CHL1 \| DISEASES 57498 \| KIDINS220 \| DISEASES 5156 \| PDGFRA \| DISEASES 1019 \| CDK4 \| DISEASES 79074 \| C2orf49 \| DISEASES 11014 \| KDELR2 \| DISEASES 3569 \| IL6 \| DISEASES 6426 \| SRSF1 \| DISEASES 4856 \| NOV \| DISEASES 5460 \| POU5F1 \| DISEASES 7057 \| THBS1 \| DISEASES 23314 \| SATB2 \| DISEASES 3417 \| IDH1 \| DISEASES 4069 \| LYZ \| DISEASES 7450 \| VWF \| DISEASES 51274 \| KLF3 \| DISEASES 5629 \| PROX1 \| DISEASES 23247 \| KIAA0556 \| DISEASES 8140 \| SLC7A5 \| DISEASES 999 \| CDH1 \| DISEASES 5159 \| PDGFRB \| DISEASES 2324 \| FLT4 \| DISEASES 466 \| ATF1 \| DISEASES 4481 \| MSR1 \| DISEASES 4025 \| LPO \| DISEASES 7077 \| TIMP2 \| DISEASES 25939 \| SAMHD1 \| DISEASES 2549 \| GAB1 \| DISEASES 5595 \| MAPK3 \| DISEASES 6598 \| SMARCB1 \| DISEASES 54487 \| DGCR8 \| DISEASES 6855 \| SYP \| DISEASES 23264 \| ZC3H7B \| DISEASES 7299 \| TYR \| DISEASES 3552 \| IL1A \| DISEASES 3553 \| IL1B \| DISEASES 330 \| BIRC3 \| DISEASES 4072 \| EPCAM \| DISEASES 7301 \| TYRO3 \| DISEASES 3791 \| KDR \| DISEASES 943 \| TNFRSF8 \| DISEASES 5290 \| PIK3CA \| DISEASES 1001 \| CDH3 \| DISEASES 4162 \| MCAM \| DISEASES 4811 \| NID1 \| DISEASES 5471 \| PPAT \| DISEASES 941 \| CD80 \| DISEASES 56925 \| LXN \| DISEASES 7531 \| YWHAE \| DISEASES 2247 \| FGF2 \| DISEASES 84162 \| KIAA1109 \| DISEASES 7067 \| THRA \| DISEASES 6774 \| STAT3 \| DISEASES 3383 \| ICAM1 \| DISEASES 3827 \| KNG1 \| DISEASES 1950 \| EGF \| DISEASES 27074 \| LAMP3 \| DISEASES 1119 \| CHKA \| DISEASES 5243 \| ABCB1 \| DISEASES 1021 \| CDK6 \| DISEASES 29999 \| FSCN3 \| DISEASES 1616 \| DAXX \| DISEASES 23598 \| PATZ1 \| DISEASES 8549 \| LGR5 \| DISEASES 1017 \| CDK2 \| DISEASES 2065 \| ERBB3 \| DISEASES 5925 \| RB1 \| DISEASES 2252 \| FGF7 \| DISEASES 3480 \| IGF1R \| DISEASES 5045 \| FURIN \| DISEASES 3687 \| ITGAX \| DISEASES 3394 \| IRF8 \| DISEASES 1000 \| CDH2 \| DISEASES 7157 \| TP53 \| DISEASES 2064 \| ERBB2 \| DISEASES 55527 \| FEM1A \| DISEASES 207 \| AKT1 \| DISEASES 148327 \| CREB3L4 \| DISEASES 5868 \| RAB5A \| DISEASES 6769 \| STAC \| DISEASES 6423 \| SFRP2 \| DISEASES 56929 \| FEM1C \| DISEASES 1956 \| EGFR \| DISEASES 85417 \| CCNB3 \| DISEASES 54539 \| NDUFB11 \| DISEASES 4103 \| MAGEA4 \| DISEASES 9046 \| DOK2 \| DISEASES 8795 \| TNFRSF10B \| DISEASES 1030 \| CDKN2B \| DISEASES 3439 \| IFNA1 \| DISEASES 4851 \| NOTCH1 \| DISEASES 9712 \| USP6NL \| DISEASES 23082 \| PPRC1 \| DISEASES 472 \| ATM \| DISEASES 3145 \| HMBS \| DISEASES 9219 \| MTA2 \| DISEASES 7424 \| VEGFC \| DISEASES 5805 \| PTS \| DISEASES 4613 \| MYCN \| DISEASES 2241 \| FER \| DISEASES 5281 \| PIGF \| DISEASES 2321 \| FLT1 \| DISEASES 10413 \| YAP1 \| DISEASES 2697 \| GJA1 \| DISEASES 5903 \| RANBP2 \| DISEASES 221895 \| JAZF1 \| DISEASES 7070 \| THY1 \| DISEASES 84959 \| UBASH3B \| DISEASES 7345 \| UCHL1 \| DISEASES 9510 \| ADAMTS1 \| DISEASES 9947 \| MAGEC1 \| DISEASES 843 \| CASP10 \| DISEASES 1436 \| CSF1R \| DISEASES 1633 \| DCK \| DISEASES 6750 \| SST \| DISEASES 23420 \| NOMO1 \| DISEASES 5468 \| PPARG \| DISEASES 348174 \| CLEC18A \| DISEASES 3815 \| KIT \| DISEASES 673 \| BRAF \| DISEASES 3242 \| HPD \| DISEASES 909 \| CD1A \| DISEASES 57519 \| STARD9 \| DISEASES 55223 \| TRIM62 \| DISEASES 8209 \| C21orf33 \| DISEASES 30815 \| ST6GALNAC6 \| DISEASES 2264 \| FGFR4 \| DISEASES 3856 \| KRT8 \| DISEASES 7471 \| WNT1 \| DISEASES 2256 \| FGF11 \| DISEASES 7542 \| ZFPL1 \| DISEASES 10630 \| PDPN \| DISEASES 2487 \| FRZB \| DISEASES 4286 \| MITF \| DISEASES 152185 \| SPICE1 \| DISEASES 213 \| ALB \| DISEASES 308 \| ANXA5 \| DISEASES 134265 \| AFAP1L1 \| DISEASES 3562 \| IL3 \| DISEASES 1437 \| CSF2 \| DISEASES 2661 \| GDF9 \| DISEASES 4869 \| NPM1 \| DISEASES 26872 \| STEAP1 \| DISEASES 216 \| ALDH1A1 \| DISEASES 10935 \| PRDX3 \| DISEASES 158067 \| AK8 \| DISEASES 55027 \| HEATR3 \| DISEASES 121599 \| SPIC \| DISEASES 10818 \| FRS2 \| DISEASES 54765 \| TRIM44 \| DISEASES 3611 \| ILK \| DISEASES 201161 \| CENPV \| DISEASES 7184 \| HSP90B1 \| DISEASES 290 \| ANPEP \| DISEASES 5347 \| PLK1 \| DISEASES 4665 \| NAB2 \| DISEASES 6778 \| STAT6 \| DISEASES 124872 \| B4GALNT2 \| DISEASES 1398 \| CRK \| DISEASES 762 \| CA4 \| DISEASES 147945 \| NLRP4 \| DISEASES 148156 \| ZNF558 \| DISEASES 5436 \| POLR2G \| DISEASES 3960 \| LGALS4 \| DISEASES 4255 \| MGMT \| DISEASES 79058 \| ASPSCR1 \| DISEASES 133418 \| EMB \| DISEASES 5604 \| MAP2K1 \| DISEASES 598 \| BCL2L1 \| DISEASES 3479 \| IGF1 \| DISEASES 3308 \| HSPA4 \| DISEASES 170626 \| XAGE3 \| DISEASES 3688 \| ITGB1 \| DISEASES 1493 \| CTLA4 \| DISEASES 121355 \| GTSF1 \| DISEASES 171558 \| PTCRA \| DISEASES 259249 \| MRGPRX1 \| DISEASES 6504 \| SLAMF1 \| DISEASES 2353 \| FOS \| DISEASES 23261 \| CAMTA1 \| DISEASES 3669 \| ISG20 \| DISEASES 2119 \| ETV5 \| DISEASES 9451 \| EIF2AK3 \| DISEASES 794 \| CALB2 \| DISEASES 9902 \| MRC2 \| DISEASES 54205 \| CYCS \| DISEASES 10589 \| DRAP1 \| DISEASES 27087 \| B3GAT1 \| DISEASES 9648 \| GCC2 \| DISEASES 57124 \| CD248 \| DISEASES 2147 \| F2 \| DISEASES 6954 \| TCP11 \| DISEASES 5340 \| PLG \| DISEASES 7015 \| TERT \| DISEASES 3265 \| HRAS \| DISEASES 6868 \| ADAM17 \| DISEASES 947 \| CD34 \| DISEASES 836 \| CASP3 \| DISEASES 10432 \| RBM14 \| DISEASES 55279 \| ZNF654 \| DISEASES 8837 \| CFLAR \| DISEASES 1464 \| CSPG4 \| DISEASES 85478 \| CCDC65 \| DISEASES 3172 \| HNF4A \| DISEASES 10102 \| TSFM \| DISEASES 57101 \| ANO2 \| DISEASES 7030 \| TFE3 \| DISEASES 354 \| KLK3 \| DISEASES 2580 \| GAK \| DISEASES 1191 \| CLU \| DISEASES 7298 \| TYMS \| DISEASES 23512 \| SUZ12 \| DISEASES 115207 \| KCTD12 \| DISEASES 4233 \| MET \| DISEASES 79643 \| CHMP6 \| DISEASES 8824 \| CES2 \| DISEASES 10956 \| OS9 \| DISEASES 260436 \| FDCSP \| DISEASES 4684 \| NCAM1 \| DISEASES 56676 \| ASCL3 \| DISEASES 55884 \| WSB2 \| DISEASES 2146 \| EZH2 \| DISEASES 8289 \| ARID1A \| DISEASES 54556 \| ING3 \| DISEASES 27436 \| EML4 \| DISEASES 2253 \| FGF8 \| DISEASES 2118 \| ETV4 \| DISEASES 3039 \| HBA1 \| DISEASES 4312 \| MMP1 \| DISEASES 6657 \| SOX2 \| DISEASES 341416 \| OR6C2 \| DISEASES 23527 \| ACAP2 \| DISEASES 7791 \| ZYX \| DISEASES 8938 \| BAIAP3 \| DISEASES 2314 \| FLII \| DISEASES 1555 \| CYP2B6 \| DISEASES 7525 \| YES1 \| DISEASES 5518 \| PPP2R1A \| DISEASES 2932 \| GSK3B \| DISEASES 154141 \| MBOAT1 \| DISEASES 5241 \| PGR \| DISEASES 51193 \| ZNF639 \| DISEASES 2300 \| FOXL1 \| DISEASES 283971 \| CLEC18C \| DISEASES 3052 \| HCCS \| DISEASES 2187 \| FANCB \| DISEASES 353500 \| BMP8A \| DISEASES 1435 \| CSF1 \| DISEASES 5074 \| PAWR \| DISEASES 221937 \| FOXK1 \| DISEASES 29933 \| GPR132 \| DISEASES 64764 \| CREB3L2 \| DISEASES 3855 \| KRT7 \| DISEASES 2811 \| GP1BA \| DISEASES 326340 \| ZAR1 \| DISEASES 7378 \| UPP1 \| DISEASES 842 \| CASP9 \| DISEASES 5155 \| PDGFB \| DISEASES 113828 \| FAM83F \| DISEASES 23542 \| MAPK8IP2 \| DISEASES 6938 \| TCF12 \| DISEASES 7490 \| WT1 \| DISEASES 2242 \| FES \| DISEASES 71 \| ACTG1 \| DISEASES 11187 \| PKP3 \| DISEASES 6401 \| SELE \| DISEASES 796 \| CALCA \| DISEASES 126282 \| TNFAIP8L1 \| DISEASES 6007 \| RHD \| DISEASES 942 \| CD86 \| DISEASES 8338 \| HIST2H2AC \| DISEASES 5727 \| PTCH1 \| DISEASES 1485 \| CTAG1B \| DISEASES 8013 \| NR4A3 \| DISEASES 4600 \| MX2 \| DISEASES 9502 \| XAGE2 \| DISEASES 2152 \| F3 \| DISEASES 5787 \| PTPRB \| DISEASES 5133 \| PDCD1 \| DISEASES 5501 \| PPP1CC \| DISEASES 3320 \| HSP90AA1 \| DISEASES 115557 \| ARHGEF25 \| DISEASES 139065 \| SLITRK4 \| DISEASES 3842 \| TNPO1 \| DISEASES 81608 \| FIP1L1 \| DISEASES 29015 \| SLC43A3 \| DISEASES 5529 \| PPP2R5E \| DISEASES 200162 \| SPAG17 \| DISEASES 1576 \| CYP3A4 \| DISEASES 3091 \| HIF1A \| DISEASES 23462 \| HEY1 \| DISEASES 2246 \| FGF1 \| DISEASES 23583 \| SMUG1 \| DISEASES 7430 \| EZR \| DISEASES 857 \| CAV1 \| DISEASES 8459 \| TPST2 \| DISEASES 55893 \| ZNF395 \| DISEASES 1978 \| EIF4EBP1 \| DISEASES 5781 \| PTPN11 \| DISEASES 1447 \| CSN2 \| DISEASES 5747 \| PTK2 \| DISEASES 259197 \| NCR3 \| DISEASES 2305 \| FOXM1 \| DISEASES 344901 \| OSTN \| DISEASES 9623 \| TCL1B \| DISEASES 23405 \| DICER1 \| DISEASES 1003 \| CDH5 \| DISEASES 1499 \| CTNNB1 \| DISEASES 900 \| CCNG1 \| DISEASES 4771 \| NF2 \| DISEASES 7620 \| ZNF69 \| DISEASES 121549 \| ASCL4 \| DISEASES 1399 \| CRKL \| DISEASES 5154 \| PDGFA \| DISEASES 2534 \| FYN \| DISEASES 55107 \| ANO1 \| DISEASES 23386 \| NUDCD3 \| DISEASES 80781 \| COL18A1 \| DISEASES 331 \| XIAP \| DISEASES 1785 \| DNM2 \| DISEASES 5979 \| RET \| DISEASES 355 \| FAS \| DISEASES 5265 \| SERPINA1 \| DISEASES 6898 \| TAT \| DISEASES 51155 \| HN1 \| DISEASES 10905 \| MAN1A2 \| DISEASES 4100 \| MAGEA1 \| DISEASES 11186 \| RASSF1 \| DISEASES 79930 \| DOK3 \| DISEASES 60 \| ACTB \| DISEASES 5079 \| PAX5 \| DISEASES 26136 \| TES \| DISEASES 6714 \| SRC \| DISEASES 4763 \| NF1 \| DISEASES 1969 \| EPHA2 \| DISEASES 841 \| CASP8 \| DISEASES 8852 \| AKAP4 \| DISEASES 6525 \| SMTN \| DISEASES 2526 \| FUT4 \| DISEASES 56980 \| PRDM10 \| DISEASES 153769 \| SH3RF2 \| DISEASES 9332 \| CD163 \| DISEASES 56474 \| CTPS2 \| DISEASES 2013 \| EMP2 \| DISEASES 1999 \| ELF3 \| DISEASES 4151 \| MB \| DISEASES 4192 \| MDK \| DISEASES 6693 \| SPN \| DISEASES 2114 \| ETS2 \| DISEASES 2157 \| F8 \| DISEASES 5599 \| MAPK8 \| DISEASES 4311 \| MME \| DISEASES 25937 \| WWTR1 \| DISEASES 6238 \| RRBP1 \| DISEASES 6663 \| SOX10 \| DISEASES 4916 \| NTRK3 \| DISEASES 6772 \| STAT1 \| DISEASES 7150 \| TOP1 \| DISEASES 2475 \| MTOR \| DISEASES 51438 \| MAGEC2 \| DISEASES 6136 \| RPL12 \| DISEASES 800 \| CALD1 \| DISEASES 10724 \| MGEA5 \| DISEASES 3880 \| KRT19 \| DISEASES 9853 \| RUSC2 \| DISEASES 159 \| ADSS \| DISEASES 142 \| PARP1 \| DISEASES 3020 \| H3F3A \| DISEASES 51514 \| DTL \| DISEASES 343035 \| RD3 \| DISEASES 1378 \| CR1 \| DISEASES 1380 \| CR2 \| DISEASES 4194 \| MDM4 \| DISEASES 5788 \| PTPRC \| DISEASES 5743 \| PTGS2 \| DISEASES 51534 \| VTA1 \| DISEASES 356 \| FASLG \| DISEASES 117157 \| SH2D1B \| DISEASES 1490 \| CTGF \| DISEASES 911 \| CD1C \| DISEASES 10763 \| NES \| DISEASES 6016 \| RIT1 \| DISEASES 4582 \| MUC1 \| DISEASES 387119 \| CEP85L \| DISEASES 6098 \| ROS1 \| DISEASES 7170 \| TPM3 \| DISEASES 6280 \| S100A9 \| DISEASES 353133 \| LCE1C \| DISEASES 1520 \| CTSS \| DISEASES 4170 \| MCL1 \| DISEASES 8349 \| HIST2H2BE \| DISEASES 8337 \| HIST2H2AA3 \| DISEASES 8515 \| ITGA10 \| DISEASES 23195 \| MDN1 \| DISEASES 914 \| CD2 \| DISEASES 4803 \| NGF \| DISEASES 4893 \| NRAS \| DISEASES 3897 \| L1CAM \| DISEASES 26576 \| SRPK3 \| DISEASES 10360 \| NPM3 \| DISEASES 4102 \| MAGEA3 \| DISEASES 158521 \| FMR1NB \| DISEASES 959 \| CD40LG \| DISEASES 51013 \| EXOSC1 \| DISEASES 9406 \| ZRANB2 \| DISEASES 1647 \| GADD45A \| DISEASES 5236 \| PGM1 \| DISEASES 1791 \| DNTT \| DISEASES 6005 \| RHAG \| DISEASES 3725 \| JUN \| DISEASES 860 \| RUNX2 \| DISEASES 9334 \| B4GALT5 \| DISEASES 5728 \| PTEN \| DISEASES 7422 \| VEGFA \| DISEASES 83549 \| UCK1 \| DISEASES 11004 \| KIF2C \| DISEASES 64405 \| CDH22 \| DISEASES 729238 \| SFTPA2 \| DISEASES 4318 \| MMP9 \| DISEASES 25 \| ABL1 \| DISEASES 7075 \| TIE1 \| DISEASES 4904 \| YBX1 \| DISEASES 1907 \| EDN2 \| DISEASES 5453 \| POU3F1 \| DISEASES 2022 \| ENG \| DISEASES 546 \| ATRX \| DISEASES 23452 \| ANGPTL2 \| DISEASES 7321 \| UBE2D1 \| DISEASES 22943 \| DKK1 \| DISEASES 2268 \| FGR \| DISEASES 9968 \| MED12 \| DISEASES 4303 \| FOXO4 \| DISEASES 5252 \| PHF1 \| DISEASES 1896 \| EDA \| DISEASES 978 \| CDA \| DISEASES 3014 \| H2AFX \| DISEASES 5081 \| PAX7 \| DISEASES 727837 \| SSX2B \| DISEASES 2155 \| F7 \| DISEASES 3303 \| HSPA1A \| DISEASES 1460 \| CSNK2B \| DISEASES 199 \| AIF1 \| DISEASES 7088 \| TLE1 \| DISEASES 11040 \| PIM2 \| DISEASES 548313 \| SSX4B \| DISEASES 6759 \| SSX4 \| DISEASES 6756 \| SSX1 \| DISEASES 7056 \| THBD \| DISEASES 4821 \| NKX2-2 \| DISEASES 5457 \| POU4F1 \| DISEASES 7536 \| SF1 \| DISEASES 3604 \| TNFRSF9 \| DISEASES 4609 \| MYC \| DISEASES 768 \| CA9 \| DISEASES 27237 \| ARHGEF16 \| DISEASES 54880 \| BCOR \| DISEASES 23279 \| NUP160 \| DISEASES 7102 \| TSPAN7 \| DISEASES 79823 \| CAMKMT \| DISEASES 6497 \| SKI \| DISEASES 650 \| BMP2 \| DISEASES 84964 \| ALKBH6 \| DISEASES 190 \| NR0B1 \| DISEASES 1906 \| EDN1 \| DISEASES 2308 \| FOXO1 \| DISEASES 7010 \| TEK \| DISEASES 675 \| BRCA2 \| DISEASES 4507 \| MTAP \| DISEASES 3440 \| IFNA2 \| DISEASES 3456 \| IFNB1 \| DISEASES 2874 \| GPS2 \| DISEASES 22902 \| RUFY3 \| DISEASES 3486 \| IGFBP3 \| DISEASES 4267 \| CD99 \| DISEASES 2315 \| MLANA \| DISEASES 283820 \| NOMO2 \| DISEASES 29126 \| CD274 \| DISEASES 2618 \| GART \| DISEASES 55276 \| PGM2 \| DISEASES 54545 \| MTMR12 \| DISEASES 6624 \| FSCN1 \| DISEASES 11200 \| CHEK2 \| DISEASES 56341 \| PRMT8 \| DISEASES 5888 \| RAD51 \| DISEASES 5720 \| PSME1 \| DISEASES 10274 \| STAG1 \| DISEASES 28512 \| NKIRAS1 \| DISEASES 3875 \| KRT18 \| DISEASES 238 \| ALK \| DISEASES 3681 \| ITGAD \| DISEASES 284217 \| LAMA1 \| DISEASES 5077 \| PAX3 \| DISEASES 2113 \| ETS1 \| DISEASES 12 \| SERPINA3 \| DISEASES 80310 \| PDGFD \| DISEASES 4831 \| NME2 \| DISEASES 27032 \| ATP2C1 \| DISEASES 440603 \| BCL2L15 \| DISEASES 2719 \| GPC3 \| DISEASES 9349 \| RPL23 \| DISEASES 51520 \| LARS \| DISEASES 64400 \| AKTIP \| DISEASES 9255 \| AIMP1 \| DISEASES 5530 \| PPP3CA \| DISEASES 6696 \| SPP1 \| DISEASES 2132 \| EXT2 \| DISEASES 174 \| AFP \| DISEASES 5744 \| PTHLH \| DISEASES 2737 \| GLI3 \| DISEASES 55259 \| CASC1 \| DISEASES 4773 \| NFATC2 \| DISEASES 89797 \| NAV2 \| DISEASES 2120 \| ETV6 \| DISEASES 342900 \| LEUTX \| DISEASES 80380 \| PDCD1LG2 \| DISEASES 5609 \| MAP2K7 \| DISEASES 389136 \| VGLL3 \| DISEASES 5634 \| PRPS2 \| DISEASES 4599 \| MX1 \| DISEASES 23532 \| PRAME \| DISEASES 408050 \| NOMO3 \| DISEASES 6093 \| ROCK1 \| DISEASES 8091 \| HMGA2 \| DISEASES 152579 \| SCFD2 \| DISEASES 23198 \| PSME4 \| DISEASES 7122 \| CLDN5 \| DISEASES 55120 \| FANCL \| DISEASES 2115 \| ETV1 \| DISEASES 7018 \| TF \| DISEASES 50489 \| CD207 \| DISEASES 29072 \| SETD2 \| DISEASES 7852 \| CXCR4 \| DISEASES 9938 \| ARHGAP25 \| DISEASES 1385 \| CREB1 \| DISEASES 84812 \| PLCD4 \| DISEASES 1111 \| CHEK1 \| DISEASES 65250 \| C5orf42 \| DISEASES 5601 \| MAPK9 \| DISEASES 23109 \| DDN \| DISEASES 3481 \| IGF2 \| DISEASES 6222 \| RPS18 \| DISEASES 2260 \| FGFR1 \| DISEASES 87178 \| PNPT1 \| DISEASES 1438 \| CSF2RA \| DISEASES 1029 \| CDKN2A \| DISEASES 7849 \| PAX8 \| DISEASES 734 \| OSGIN2 \| DISEASES 653509 \| SFTPA1 \| DISEASES 257415 \| FAM133B \| DISEASES 960 \| CD44 \| DISEASES 7124 \| TNF \| DISEASES 2352 \| FOLR3 \| DISEASES 56157 \| TEX13A \| DISEASES 10499 \| NCOA2 \| DISEASES 6878 \| TAF6 \| DISEASES 2313 \| FLI1 \| DISEASES 2130 \| EWSR1 \| DISEASES 7072 \| TIA1 \| DISEASES 7465 \| WEE1 \| DISEASES 6490 \| PMEL \| DISEASES 400745 \| SH2D5 \| DISEASES 30000 \| TNPO2 \| DISEASES 2263 \| FGFR2 \| DISEASES 3586 \| IL10 \| DISEASES 6760 \| SS18 \| DISEASES 8842 \| PROM1 \| DISEASES 6513 \| SLC2A1 \| DISEASES 389072 \| PLEKHM3 \| DISEASES 4193 \| MDM2 \| DISEASES 4585 \| MUC4 \| DISEASES 8125 \| ANP32A \| DISEASES 672 \| BRCA1 \| DISEASES 30816 \| ERVW-1 \| DISEASES 127933 \| UHMK1 \| DISEASES 55534 \| MAML3 \| DISEASES 54540 \| FAM193B \| DISEASES 134145 \| FAM173B \| DISEASES 56034 \| PDGFC \| DISEASES 1977 \| EIF4E \| DISEASES 100507249 \| C8orf17 \| DISEASES 4067 \| LYN \| DISEASES 4168 \| MCF2 \| DISEASES 4914 \| NTRK1 \| DISEASES 2197 \| FAU \| DISEASES 90993 \| CREB3L1 \| DISEASES 56144 \| PCDHA4 \| DISEASES 6207 \| RPS13 \| DISEASES 9973 \| CCS \| DISEASES 930 \| CD19 \| DISEASES 55733 \| HHAT \| DISEASES 3684 \| ITGAM \| DISEASES 6999 \| TDO2 \| DISEASES 4850 \| CNOT4 \| DISEASES 5125 \| PCSK5 \| DISEASES 1649 \| DDIT3 \| DISEASES 5228 \| PGF \| DISEASES 100288687 \| DUX4 \| DISEASES 653545 \| DUX4L5 \| DISEASES 161436 \| EML5 \| DISEASES 101 \| ADAM8 \| DISEASES 10607 \| TBL3 \| DISEASES 8148 \| TAF15 \| DISEASES 647219 \| ASCL5 \| DISEASES 54938 \| SARS2 \| DISEASES 57000 \| GSN-AS1 \| DISEASES 106660612 \| LINC00680 \| DISEASES 100507540 \| LINC01504 \| DISEASES 5820 \| PVT1 \| DISEASES 100507308 \| TARID \| DISEASES
Locus	(Waiting for update.)

Disease ID	529
Disease	sarcoma
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:128) HP:0002664 \| Neoplasia \| 128 HP:0001909 \| Leukemia \| 17 HP:0012034 \| Liposarcoma \| 12 HP:0002665 \| Lymphoma \| 12 HP:0004808 \| Acute myelogenous leukemia \| 11 HP:0002835 \| Aspiration \| 10 HP:0100242 \| Sarcoma \| 10 HP:0030731 \| Carcinoma \| 10 HP:0012324 \| Myeloid leukemia \| 10 HP:0012315 \| Histiocytoma \| 8 HP:0002859 \| Rhabdomyosarcoma \| 8 HP:0012254 \| Ewing's sarcoma \| 7 HP:0002721 \| Immunodeficiency \| 6 HP:0012531 \| Pain \| 6 HP:0002861 \| Melanoma \| 6 HP:0002202 \| Pleural effusion \| 5 HP:0001548 \| Overgrowth \| 4 HP:0100723 \| Gastrointestinal stroma tumor \| 4 HP:0002669 \| Osteosarcoma \| 4 HP:0030065 \| Primitive neuroectodermal tumor \| 4 HP:0001289 \| Confusion \| 4 HP:0200058 \| Angiosarcoma \| 3 HP:0003006 \| Neuroblastoma \| 3 HP:0003473 \| Fatigable weakness \| 3 HP:0001369 \| Arthritis \| 3 HP:0001945 \| Fever \| 3 HP:0012189 \| Hodgkin disease \| 3 HP:0001067 \| Neurofibromas \| 3 HP:0002860 \| Squamous cell carcinoma \| 3 HP:0005506 \| Chronic myeloid leukemia \| 3 HP:0004836 \| Acute promyelocytic leukemia \| 3 HP:0100243 \| Leiomyosarcoma \| 3 HP:0012539 \| Non-Hodgkin lymphoma \| 3 HP:0002863 \| Myelodysplastic syndrome \| 2 HP:0002107 \| Collapsed lung \| 2 HP:0100697 \| Neurofibrosarcoma \| 2 HP:0010614 \| Fibroma \| 2 HP:0002716 \| Lymph node hyperplasia \| 2 HP:0000099 \| Glomerular nephritis \| 2 HP:0002488 \| Acute leukemias \| 2 HP:0000718 \| Aggressive behaviour \| 2 HP:0001402 \| Hepatocellular carcinoma \| 2 HP:0012570 \| Synovial sarcoma \| 2 HP:0002176 \| Spinal cord compression \| 2 HP:0100244 \| Fibrosarcoma \| 2 HP:0000131 \| Uterine leiomyoma \| 2 HP:0012578 \| Membranous glomerulonephritis \| 2 HP:0100615 \| Neoplasm of the ovary \| 2 HP:0000716 \| Depression \| 2 HP:0003765 \| Psoriasis \| 2 HP:0005523 \| Lymphoproliferative disorder \| 2 HP:0001903 \| Anemia \| 2 HP:0030127 \| Endometriosis \| 2 HP:0001875 \| Neutropenia \| 2 HP:0000083 \| Renal insufficiency \| 2 HP:0001055 \| Erysipelas \| 2 HP:0012490 \| Inflammation of fat tissue \| 2 HP:0002840 \| Lymphadenitis \| 2 HP:0009733 \| Glioma \| 2 HP:0002583 \| Colitis \| 1 HP:0001880 \| Eosinophilia \| 1 HP:0100806 \| Sepsis \| 1 HP:0001271 \| Polyneuropathy \| 1 HP:0100843 \| Glioblastoma \| 1 HP:0001635 \| Congestive heart failure \| 1 HP:0001907 \| Thromboembolic disease \| 1 HP:0002617 \| Aneurysmal dilatation \| 1 HP:0030448 \| Soft tissue sarcoma \| 1 HP:0001045 \| Blotchy loss of skin color \| 1 HP:0030430 \| Pinched nerve \| 1 HP:0002894 \| Neoplasia of the pancreas \| 1 HP:0002027 \| Abdominal pain \| 1 HP:0040184 \| Oral hemorrhage \| 1 HP:0009725 \| Bladder neoplasm \| 1 HP:0005521 \| Disseminated intravascular coagulation \| 1 HP:0000086 \| Ectopic kidney \| 1 HP:0004736 \| Crossed fused renal ectopia \| 1 HP:0002754 \| Bone infection \| 1 HP:0001362 \| Cranial defect \| 1 HP:0030426 \| Ossifying fibroma \| 1 HP:0200034 \| Papule \| 1 HP:0012203 \| Onychomycosis \| 1 HP:0003774 \| End-stage renal failure \| 1 HP:0100614 \| Muscle inflammation \| 1 HP:0002895 \| Papillary thyroid carcinoma \| 1 HP:0100009 \| Intracranial meningioma \| 1 HP:0100792 \| Acantholysis \| 1 HP:0001251 \| Ataxia \| 1 HP:0012125 \| Prostate cancer \| 1 HP:0002955 \| Granulomatosis \| 1 HP:0002243 \| Protein-losing enteropathy \| 1 HP:0003690 \| Limb weakness \| 1 HP:0011880 \| Acute disseminated intravascular coagulation \| 1 HP:0012378 \| Fatigue \| 1 HP:0100008 \| Schwann cell tumour \| 1 HP:0030242 \| Blood clot in portal vein \| 1 HP:0001298 \| Encephalopathy \| 1 HP:0005214 \| Bowel obstruction \| 1 HP:0100570 \| Carcinoid tumor \| 1 HP:0002960 \| Autoimmune condition \| 1 HP:0030061 \| Neuroectodermal neoplasm \| 1 HP:0004820 \| Acute myelomonocytic leukemia \| 1 HP:0003003 \| Colon cancer \| 1 HP:0001370 \| Rheumatoid arthritis \| 1 HP:0001973 \| Autoimmune thrombocytopenia \| 1 HP:0001050 \| Plethora \| 1 HP:0002242 \| Enteropathy \| 1 HP:0001047 \| Atopic dermatitis \| 1 HP:0004315 \| IgG deficiency \| 1 HP:0100279 \| Ulcerative colitis \| 1 HP:0001337 \| Tremor \| 1 HP:0003002 \| Breast carcinoma \| 1 HP:0006721 \| Acute lymphocytic leukemia \| 1 HP:0000939 \| Osteoporosis \| 1 HP:0001873 \| Low platelet count \| 1 HP:0200036 \| Skin nodule \| 1 HP:0100647 \| Morbus Basedow \| 1 HP:0000956 \| Keratosis nigricans \| 1 HP:0004845 \| Acute monoblastic leukemia \| 1 HP:0000952 \| Yellow skin \| 1 HP:0002890 \| Thyroid carcinoma \| 1 HP:0001394 \| Hepatic cirrhosis \| 1 HP:0007340 \| Lower limb weakness \| 1 HP:0010550 \| Paraplegia \| 1 HP:0100526 \| Neoplasm of the lung \| 1 HP:0030186 \| Essential tremor \| 1 HP:0001541 \| Ascites \| 1 HP:0002108 \| Spontaneous pneumothorax \| 1

Disease ID	529
Disease	sarcoma
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:16) C0009450 \| infection \| 33 C0030193 \| pain \| 6 C0153676 \| lung metastases \| 5 C0153690 \| bone metastases \| 5 C0153676 \| lung metastasis \| 5 C0153676 \| pulmonary metastases \| 2 C0153676 \| pulmonary metastasis \| 2 C0220650 \| brain metastasis \| 2 C0494165 \| liver metastases \| 1 C0040053 \| thrombosis \| 1 C0019080 \| hemorrhage \| 1 C0017636 \| glioblastoma \| 1 C0002991 \| sclerosing hemangiomas \| 1 C0000889 \| acanthosis nigricans \| 1 C1332128 \| peritoneal carcinomatosis \| 1 C0220650 \| brain metastases \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:20)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs1042522	22205265	7157	TP53	umls:C1261473	BeFree	The functional MDM2 T309G genetic variant but not P53 Arg72Pro polymorphism is associated with risk of sarcomas: a meta-analysis.	0.400032709	2012	TP53	17	7676154	G	T,C
rs1042522	22205265	4193	MDM2	umls:C1261473	BeFree	The functional MDM2 T309G genetic variant but not P53 Arg72Pro polymorphism is associated with risk of sarcomas: a meta-analysis.	0.038322962	2012	TP53	17	7676154	G	T,C
rs104886003	NA	5290	PIK3CA	umls:C1261473	CLINVAR	NA	0.241357209	NA	PIK3CA	3	179218303	G	A
rs113488022	21326296	673	BRAF	umls:C1261473	BeFree	Frequent somatic mutations of BRAF (v-raf murine sarcoma viral oncogene homolog B) exon T1799A, which are implicated in the initial events of promutagenic cellular proliferation, are detected in both malignant melanomas (MM) and melanocytic nevi (MN).	0.003800186	2011	BRAF	7	140753336	A	T,G,C
rs113488022	23909652	673	BRAF	umls:C1261473	BeFree	Vemurafenib, a selective BRAF (v-raf murine sarcoma viral oncogene homologue B1) kinase inhibitor, is a new targeted biotherapy that improves survival in patients with metastatic melanomas harbouring the BRAF V600E mutation.	0.003800186	2013	BRAF	7	140753336	A	T,G,C
rs113488022	21430505	673	BRAF	umls:C1261473	BeFree	To explore the mutation frequencies of BRAF(V600E) (V-raf murine sarcoma virus oncogene homolog B1) and NRAS (neuroblastoma ras viral oncogene homolog) codon 61 in CMNs of Chinese, we selected 55 paraffin-embedded tissue blocks, including 37 cases of medium CMNs (1.5-20cm) and 18 cases of giant CMNs (>20 cm).	0.003800186	2011	BRAF	7	140753336	A	T,G,C
rs113488022	25039578	673	BRAF	umls:C1261473	BeFree	BRAF (v-raf murine sarcoma viral oncogene homologue B) V600E mutations have been detected with high frequency in melanocytic naevi.	0.003800186	2014	BRAF	7	140753336	A	T,G,C
rs113488022	24527759	673	BRAF	umls:C1261473	BeFree	In many ERK1/2-dependent tumour cell lines, inhibition of BRAF(V600E) (v-raf murine sarcoma viral oncogene homologue B1, V600E mutation) or MEK1/2 (mitogen-activated protein kinase/ERK kinase 1/2) had very little effect on BIK expression, whereas BIM(EL) was strongly up-regulated.	0.003800186	2014	BRAF	7	140753336	A	T,G,C
rs113488022	16691193	673	BRAF	umls:C1261473	BeFree	To investigate whether the frequency of the BRAF(V600E) (V-raf murine sarcoma virus oncogene homolog B1) mutation in melanocytic nevi is associated with sun exposure patterns, we examined 120 acquired melanocytic nevi excised from various anatomic sites, including glabrous skin, as well as 62 congenital nevi.	0.003800186	2006	BRAF	7	140753336	A	T,G,C
rs113488022	24720374	673	BRAF	umls:C1261473	BeFree	Histiocytic sarcoma exhibited the highest rate of BRAF(V600E) (62.5%, five of eight), followed by Langerhans cell tumours (25%, seven of 28), FDC sarcoma (18.5%, five of 27) and giant cell tumour (6.7%, two of 30).	0.003800186	2014	BRAF	7	140753336	A	T,G,C
rs113488022	24117833	673	BRAF	umls:C1261473	BeFree	One melanoma-sarcoma pair showed identical BRAF V600E mutations.	0.003800186	2013	BRAF	7	140753336	A	T,G,C
rs11540652	NA	7157	TP53	umls:C1261473	CLINVAR	NA	0.400032709	NA	TP53	17	7674220	C	T
rs11540654	22205265	4193	MDM2	umls:C1261473	BeFree	The functional MDM2 T309G genetic variant but not P53 Arg72Pro polymorphism is associated with risk of sarcomas: a meta-analysis.	0.038322962	2012	TP53	17	7676040	C	T,G,A
rs11540654	22205265	7157	TP53	umls:C1261473	BeFree	The functional MDM2 T309G genetic variant but not P53 Arg72Pro polymorphism is associated with risk of sarcomas: a meta-analysis.	0.400032709	2012	TP53	17	7676040	C	T,G,A
rs121913254	23382236	6035	RNASE1	umls:C1261473	BeFree	We show that the human sarcoma cell line HT1080 harbors both NRAS(Q61K) and RAC1(N92I) mutant proteins.	0.000814326	2013	NRAS	1	114713909	G	T,C
rs121913254	23382236	4893	NRAS	umls:C1261473	BeFree	We show that the human sarcoma cell line HT1080 harbors both NRAS(Q61K) and RAC1(N92I) mutant proteins.	0.002909916	2013	NRAS	1	114713909	G	T,C
rs121913254	23382236	5879	RAC1	umls:C1261473	BeFree	We show that the human sarcoma cell line HT1080 harbors both NRAS(Q61K) and RAC1(N92I) mutant proteins.	0.000814326	2013	NRAS	1	114713909	G	T,C
rs1346044	18271933	7486	WRN	umls:C1261473	BeFree	Association of a missense single nucleotide polymorphism, Cys1367Arg of the WRN gene, with the risk of bone and soft tissue sarcomas in Japan.	0.005634266	2008	WRN;LOC105379359	8	31167138	T	C
rs17655	16646069	2073	ERCC5	umls:C1261473	BeFree	Our results raise the potential implication of the XPG Asp1104His polymorphism in the occurrence of chromosomal translocations associated with specific subtypes of sarcomas.	0.005634266	2006	ERCC5;BIVM-ERCC5	13	102875652	G	C
rs188957694	16166291	2099	ESR1	umls:C1261473	BeFree	The majority of spontaneous and DMBA-induced carcinomas and sarcomas from p53(R270H/+)WAPCre mice is estrogen receptor alpha positive, and expression profiles of genes also implicated in human breast cancer appear similarly altered.	0.000542884	2005	ESR1	6	151944218	G	A

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:16)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C1261473	azacitidine	D001374	320-67-2	sarcoma	MESH:D012509	marker/mechanism	2408741
C1261473	caffeine	D002110	1958/8/2	sarcoma	MESH:D012509	therapeutic	10928167
C1261473	cyclophosphamide	D003520	50-18-0	sarcoma	MESH:D012509	therapeutic	15205092
C1261473	cisplatin	D002945	15663-27-1	sarcoma	MESH:D012509	therapeutic	10928167
C1261473	epirubicin	D015251	56420-45-2	sarcoma	MESH:D012509	therapeutic	16205946
C1261473	fluorouracil	D005472	51-21-8	sarcoma	MESH:D012509	therapeutic	6603024
C1261473	leucovorin	D002955	1958/5/9	sarcoma	MESH:D012509	therapeutic	6603024
C1261473	ifosfamide	D007069	3778-73-2	sarcoma	MESH:D012509	therapeutic	10473106
C1261473	lovastatin	D008148	75330-75-5	sarcoma	MESH:D012509	therapeutic	10815931
C1261473	medroxyprogesterone acetate	D017258	71-58-9	sarcoma	MESH:D012509	therapeutic	2947675
C1261473	mesna	D015080	19767-45-4	sarcoma	MESH:D012509	therapeutic	2858016
C1261473	methotrexate	D008727	1959/5/2	sarcoma	MESH:D012509	therapeutic	3047339
C1261473	paclitaxel	D017239	-	sarcoma	MESH:D012509	therapeutic	18074150
C1261473	streptozocin	D013311	18883-66-4	sarcoma	MESH:D012509	therapeutic	135666
C1261473	trabectedin	C099150	114899-77-3	sarcoma	MESH:D012509	therapeutic	19238326
C1261473	vindesine	D014751	53643-48-4	sarcoma	MESH:D012509	therapeutic	7438126

FDA approved drug and dosage information(Total Drugs:1)
DiseaseID	Drug_name	active_ingredients	strength	Dosage Form/Route	Marketing Status	TE code	RLD	RS
MESH:D012509	mevacor	lovastatin	10MG Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons	TABLET;ORAL	Discontinued	None	Yes	No

FDA labeling changes(Total Drugs:1)
DiseaseID	Pediatric_Labeling_Date	Trade_Name	Generic_Name_or_Proper_Name	Indications Studied	Label Changes Summary	Product Labeling	BPCA(B)	PREA(P)	BPCA(B) and PREA(P)	Pediatric Rule (R)	Sponsor	Pediatric Exclusivity Granted Date	NNPS
MESH:D012509	02/14/2002	mevacor	lovastatin	Heterozygous Familial Hypercholesterolemia	New indication in adolescent boys and girls (at least one year post-menarche) 10-17 years of age	Labeling	B	-	-	-	Merck	07/17/2001	FALSE'