PedAM
Pediatric Disease Annotations & Medicines
| sagittal sinus thrombosis | ||||
| Disease ID | 1261 |
|---|---|
| Disease | sagittal sinus thrombosis |
| Definition | Formation or presence of a blood clot (THROMBUS) in the SUPERIOR SAGITTAL SINUS or the inferior sagittal sinus. Sagittal sinus thrombosis can result from infections, hematological disorders, CRANIOCEREBRAL TRAUMA; and NEUROSURGICAL PROCEDURES. Clinical features are primarily related to the increased intracranial pressure causing HEADACHE; NAUSEA; and VOMITING. Severe cases can evolve to SEIZURES or COMA. |
| Synonym | cerebral venous thrombosis of sagittal sinus sagittal sinus superior thrombosis sagittal sinus thromboses sagittal sinus thrombosis [disease/finding] sinus thromboses, sagittal sinus thrombosis, sagittal thromboses, sagittal sinus thrombosis of superior longitudinal sinus thrombosis of superior longitudinal sinus (disorder) thrombosis of superior sagittal sinus thrombosis of superior sagittal sinus (disorder) thrombosis, sagittal sinus thrombosis, superior longitudinal sinus thrombosis, superior sagittal sinus |
| DOID | |
| UMLS | C0338575 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:14) C0338575 | sagittal sinus thrombosis | 5 C0040156 | thyrotoxicosis | 1 C0155320 | cortical blindness | 1 C1527311 | brain oedema | 1 C0040053 | thrombus | 1 C0020538 | hypertension | 1 C0040053 | thrombosis | 1 C0020255 | hydrocephalus | 1 C0151740 | intracranial hypertension | 1 C0009319 | colitis | 1 C0009324 | ulcerative colitis | 1 C0033845 | pseudotumor cerebri | 1 C0456909 | blindness | 1 C0012569 | diplopia | 1 |
| Curated Gene | Entrez_id | Symbol | Resource(Total Genes:3) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:23) 1512 | CTSH | DISEASES 718 | C3 | DISEASES 5156 | PDGFRA | DISEASES 644 | BLVRA | DISEASES 340348 | TSPAN33 | DISEASES 4968 | OGG1 | DISEASES 2147 | F2 | DISEASES 5340 | PLG | DISEASES 9377 | COX5A | DISEASES 2152 | F3 | DISEASES 81608 | FIP1L1 | DISEASES 875 | CBS | DISEASES 157680 | VPS13B | DISEASES 2157 | F8 | DISEASES 54583 | EGLN1 | DISEASES 462 | SERPINC1 | DISEASES 2155 | F7 | DISEASES 7056 | THBD | DISEASES 114899 | C1QTNF3 | DISEASES 5627 | PROS1 | DISEASES 54900 | LAX1 | DISEASES 3925 | STMN1 | DISEASES 3347 | HTN3 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1261 |
|---|---|
| Disease | sagittal sinus thrombosis |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:10) HP:0002181 | Cerebral edema | 3 HP:0000969 | Dropsy | 2 HP:0100279 | Ulcerative colitis | 1 HP:0002516 | Intracranial pressure elevation | 1 HP:0000618 | Blindness | 1 HP:0002583 | Colitis | 1 HP:0000822 | Hypertension | 1 HP:0100704 | Cortical visual impairment | 1 HP:0000238 | Nonsyndromal hydrocephalus | 1 HP:0000651 | Diplopia | 1 |
| Disease ID | 1261 |
|---|---|
| Disease | sagittal sinus thrombosis |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:1) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
Chemical(Total Drugs:3) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0338575 | aminocaproic acid | D015119 | 60-32-2 | sagittal sinus thrombosis | MESH:D020225 | marker/mechanism | 2339463 | ||
| C0338575 | carbamazepine | D002220 | 298-46-4 | sagittal sinus thrombosis | MESH:D020225 | marker/mechanism | 11086405 | ||
| C0338575 | methotrexate | D008727 | 1959/5/2 | sagittal sinus thrombosis | MESH:D020225 | marker/mechanism | 2507046 | ||
FDA approved drug and dosage information(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
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| (Waiting for update.) | |