PedAM
Pediatric Disease Annotations & Medicines
| renal cortical necrosis | ||||
| Disease ID | 1848 |
|---|---|
| Disease | renal cortical necrosis |
| Definition | Death of cells in the KIDNEY CORTEX, a common final result of various renal injuries including HYPOXIA; ISCHEMIA; and drug toxicity. |
| Synonym | kidney cortex necrosis kidney cortex necrosis [disease/finding] necrosis kidney cortex necrosis of cortex of kidney necrosis of cortex of kidney (disorder) necrosis, kidney cortex necrosis, renal cortical nephropathy nos with cortical necrosis nephropathy nos with renal cortical necrosis renal cortical necrosis nos |
| DOID | |
| UMLS | C0022656 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:9) C0035078 | renal failure | 2 C0025294 | meningococcal meningitis | 1 C0024141 | systemic lupus erythematosus | 1 C0409974 | lupus erythematosus | 1 C0022661 | chronic renal failure | 1 C0022661 | end-stage renal failure | 1 C0085278 | antiphospholipid syndrome | 1 C0019061 | hemolytic uremic syndrome | 1 C0025306 | meningococcaemia | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:26) 5020 | OXT | DISEASES 1666 | DECR1 | DISEASES 718 | C3 | DISEASES 10343 | PKDREJ | DISEASES 8455 | ATRN | DISEASES 7299 | TYR | DISEASES 8128 | ST8SIA2 | DISEASES 710 | SERPING1 | DISEASES 3087 | HHEX | DISEASES 327 | APEH | DISEASES 2147 | F2 | DISEASES 5340 | PLG | DISEASES 5345 | SERPINF2 | DISEASES 1555 | CYP2B6 | DISEASES 1237 | CCR8 | DISEASES 3363 | HTR7 | DISEASES 5979 | RET | DISEASES 2157 | F8 | DISEASES 5328 | PLAU | DISEASES 3030 | HADHA | DISEASES 2875 | GPT | DISEASES 6696 | SPP1 | DISEASES 2950 | GSTP1 | DISEASES 1029 | CDKN2A | DISEASES 85476 | GFM1 | DISEASES 102723508 | KANTR | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1848 |
|---|---|
| Disease | renal cortical necrosis |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:4) |
| Disease ID | 1848 |
|---|---|
| Disease | renal cortical necrosis |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
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| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
Chemical(Total Drugs:8) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0022656 | amphetamine | D000661 | 300-62-9 | kidney cortex necrosis | MESH:D007673 | marker/mechanism | 16133628 | ||
| C0022656 | diatrizoate | D003973 | 117-96-4 | kidney cortex necrosis | MESH:D007673 | marker/mechanism | 6697462 | ||
| C0022656 | cisplatin | D002945 | 15663-27-1 | kidney cortex necrosis | MESH:D007673 | marker/mechanism | 15464296 | ||
| C0022656 | enalapril | D004656 | 75847-73-3 | kidney cortex necrosis | MESH:D007673 | marker/mechanism | 19761811 | ||
| C0022656 | mitomycin | D016685 | 1950/7/7 | kidney cortex necrosis | MESH:D007673 | marker/mechanism | 6796250 | ||
| C0022656 | quinine | D011803 | 130-95-0 | kidney cortex necrosis | MESH:D007673 | marker/mechanism | 18343736 | ||
| C0022656 | spironolactone | D013148 | 1952/1/7 | kidney cortex necrosis | MESH:D007673 | marker/mechanism | 15245572 | ||
| C0022656 | tranexamic acid | D014148 | 1197-18-8 | kidney cortex necrosis | MESH:D007673 | marker/mechanism | 10193833 | ||
FDA approved drug and dosage information(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
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| (Waiting for update.) | |