PedAM

Pediatric Disease Annotations & Medicines


	refractive error

Disease ID	837
Disease	refractive error
Definition	Deviations from the average or standard indices of refraction of the eye through its dioptric or refractive apparatus.
Synonym	disorder of refraction disorder of refraction (disorder) disorder of refraction, nos disorder refraction disorder, refractive disorders refraction disorders, refractive error refraction error refractive error, refractive errors refraction errors refractive errors, refractive eye refraction disorder refraction disorder refraction disorder of refraction disorder, nos refraction disorders refraction error refraction errors refractive dis refractive disorder refractive disorders refractive err refractive error, nos refractive errors refractive errors [disease/finding]
DOID	DOID:9835
UMLS	C0034951
MeSH	D012030
SNOMED-CT	SNOMEDCT_US_2016_09_01:39021009
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:38) C0027092 \| myopia \| 22 C0456909 \| blindness \| 10 C0020490 \| hyperopia \| 9 C0002418 \| amblyopia \| 8 C0086543 \| cataract \| 7 C0004106 \| astigmatism \| 6 C0235238 \| cycloplegia \| 4 C0014877 \| esotropia \| 4 C0022578 \| keratoconus \| 4 C0155336 \| accommodative esotropia \| 4 C0017601 \| glaucoma \| 3 C0038379 \| strabismus \| 2 C0033075 \| presbyopia \| 2 C0028738 \| nystagmus \| 2 C0035334 \| retinitis pigmentosa \| 2 C0020490 \| hypermetropia \| 2 C0035309 \| retinopathy \| 2 C0003081 \| anisometropia \| 2 C0035333 \| retinitis \| 2 C0007789 \| cerebral palsy \| 2 C0005745 \| ptosis \| 1 C0033847 \| pseudoxanthoma elasticum \| 1 C0149931 \| migraine headache \| 1 C0035309 \| retinal disease \| 1 C0013261 \| duane syndrome \| 1 C1263846 \| attention deficit hyperactivity disorder \| 1 C0149931 \| migraine \| 1 C0700501 \| congenital nystagmus \| 1 C0037822 \| speech disorders \| 1 C0018179 \| granular corneal dystrophy \| 1 C0004352 \| autism \| 1 C0035309 \| retinal diseases \| 1 C0010036 \| corneal dystrophy \| 1 C0456909 \| vision loss \| 1 C0015397 \| eye disease \| 1 C0036454 \| visual field defects \| 1 C0015397 \| eye diseases \| 1 C0036454 \| visual field defect \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:19) LAMA2 \| 3908 \| GWASCAT TJP2 \| 9414 \| GWASCAT CACNA1D \| 776 \| GWASCAT ZMAT4 \| 79698 \| GWASCAT CHRNG \| 1146 \| GWASCAT PCCA \| 5095 \| GWASCAT ACTC1 \| 70 \| CTD_human MYO1D \| 4642 \| GWASCAT CHN1 \| 1123 \| GHR KCNQ5 \| 56479 \| GWASCAT CNDP2 \| 55748 \| GWASCAT RASGRF1 \| 5923 \| CTD_human;GWASCAT GJD2 \| 57369 \| CTD_human RBFOX1 \| 54715 \| GWASCAT GRIA4 \| 2893 \| GWASCAT SHISA6 \| 388336 \| GWASCAT PTPRR \| 5801 \| GWASCAT RORB \| 6096 \| GWASCAT C14orf39 \| 317761 \| GWASCAT
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:2) 440270 \| GOLGA8B \| infer 4233 \| MET \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:619) 401237 \| CASC15 \| DISEASES 11285 \| B4GALT7 \| DISEASES 4653 \| MYOC \| DISEASES 1634 \| DCN \| DISEASES 1951 \| CELSR3 \| DISEASES 8974 \| P4HA2 \| DISEASES 50700 \| RDH8 \| DISEASES 5351 \| PLOD1 \| DISEASES 6820 \| SULT2B1 \| DISEASES 1947 \| EFNB1 \| DISEASES 25984 \| KRT23 \| DISEASES 1652 \| DDT \| DISEASES 1414 \| CRYBB1 \| DISEASES 9362 \| CPNE6 \| DISEASES 57167 \| SALL4 \| DISEASES 10627 \| MYL12A \| DISEASES 9248 \| GPR50 \| DISEASES 7076 \| TIMP1 \| DISEASES 4313 \| MMP2 \| DISEASES 11151 \| CORO1A \| DISEASES 1512 \| CTSH \| DISEASES 2137 \| EXTL3 \| DISEASES 6422 \| SFRP1 \| DISEASES 3191 \| HNRNPL \| DISEASES 7040 \| TGFB1 \| DISEASES 3982 \| LIM2 \| DISEASES 3082 \| HGF \| DISEASES 23554 \| TSPAN12 \| DISEASES 2218 \| FKTN \| DISEASES 5949 \| RBP3 \| DISEASES 7473 \| WNT3 \| DISEASES 1277 \| COL1A1 \| DISEASES 952 \| CD38 \| DISEASES 8929 \| PHOX2B \| DISEASES 1410 \| CRYAB \| DISEASES 1075 \| CTSC \| DISEASES 55703 \| POLR3B \| DISEASES 7287 \| TULP1 \| DISEASES 2979 \| GUCA1B \| DISEASES 5961 \| PRPH2 \| DISEASES 2916 \| GRM6 \| DISEASES 2779 \| GNAT1 \| DISEASES 3769 \| KCNJ13 \| DISEASES 25806 \| VAX2 \| DISEASES 6301 \| SARS \| DISEASES 58512 \| DLGAP3 \| DISEASES 7276 \| TTR \| DISEASES 103910 \| MYL12B \| DISEASES 9525 \| VPS4B \| DISEASES 7043 \| TGFB3 \| DISEASES 9419 \| CRIPT \| DISEASES 56126 \| PCDHB10 \| DISEASES 1958 \| EGR1 \| DISEASES 7976 \| FZD3 \| DISEASES 3204 \| HOXA7 \| DISEASES 7291 \| TWIST1 \| DISEASES 8655 \| DYNLL1 \| DISEASES 79809 \| TTC21B \| DISEASES 6626 \| SNRPA \| DISEASES 5184 \| PEPD \| DISEASES 3581 \| IL9R \| DISEASES 652 \| BMP4 \| DISEASES 23002 \| DAAM1 \| DISEASES 6495 \| SIX1 \| DISEASES 59269 \| HIVEP3 \| DISEASES 5300 \| PIN1 \| DISEASES 8854 \| ALDH1A2 \| DISEASES 9526 \| MPDU1 \| DISEASES 23162 \| MAPK8IP3 \| DISEASES 3630 \| INS \| DISEASES 259232 \| NALCN \| DISEASES 64428 \| NARFL \| DISEASES 3859 \| KRT12 \| DISEASES 10912 \| GADD45G \| DISEASES 9997 \| SCO2 \| DISEASES 3911 \| LAMA5 \| DISEASES 2521 \| FUS \| DISEASES 6538 \| SLC6A11 \| DISEASES 84034 \| EMILIN2 \| DISEASES 3000 \| GUCY2D \| DISEASES 5145 \| PDE6A \| DISEASES 1131 \| CHRM3 \| DISEASES 57578 \| UNC79 \| DISEASES 5156 \| PDGFRA \| DISEASES 22873 \| DZIP1 \| DISEASES 8739 \| HRK \| DISEASES 10677 \| AVIL \| DISEASES 5959 \| RDH5 \| DISEASES 4284 \| MIP \| DISEASES 80896 \| NPL \| DISEASES 27348 \| TOR1B \| DISEASES 347733 \| TUBB2B \| DISEASES 6386 \| SDCBP \| DISEASES 6496 \| SIX3 \| DISEASES 84171 \| LOXL4 \| DISEASES 1295 \| COL8A1 \| DISEASES 1833 \| EPYC \| DISEASES 845 \| CASQ2 \| DISEASES 5687 \| PSMA6 \| DISEASES 29954 \| POMT2 \| DISEASES 3843 \| IPO5 \| DISEASES 9663 \| LPIN2 \| DISEASES 8120 \| AP3B2 \| DISEASES 9187 \| SLC24A1 \| DISEASES 8482 \| SEMA7A \| DISEASES 4016 \| LOXL1 \| DISEASES 338917 \| VSX2 \| DISEASES 7434 \| VIPR2 \| DISEASES 84662 \| GLIS2 \| DISEASES 1770 \| DNAH9 \| DISEASES 10847 \| SRCAP \| DISEASES 9739 \| SETD1A \| DISEASES 27443 \| CECR2 \| DISEASES 7011 \| TEP1 \| DISEASES 9620 \| CELSR1 \| DISEASES 7077 \| TIMP2 \| DISEASES 25939 \| SAMHD1 \| DISEASES 10133 \| OPTN \| DISEASES 4924 \| NUCB1 \| DISEASES 7299 \| TYR \| DISEASES 5033 \| P4HA1 \| DISEASES 334 \| APLP2 \| DISEASES 23024 \| PDZRN3 \| DISEASES 7301 \| TYRO3 \| DISEASES 4036 \| LRP2 \| DISEASES 55850 \| USE1 \| DISEASES 84708 \| LNX1 \| DISEASES 55669 \| MFN1 \| DISEASES 60482 \| SLC5A7 \| DISEASES 25791 \| NGEF \| DISEASES 57192 \| MCOLN1 \| DISEASES 84695 \| LOXL3 \| DISEASES 79644 \| SRD5A3 \| DISEASES 1421 \| CRYGD \| DISEASES 8452 \| CUL3 \| DISEASES 2743 \| GLRB \| DISEASES 374 \| AREG \| DISEASES 2247 \| FGF2 \| DISEASES 2255 \| FGF10 \| DISEASES 5276 \| SERPINI2 \| DISEASES 10686 \| CLDN16 \| DISEASES 11107 \| PRDM5 \| DISEASES 2651 \| GCNT2 \| DISEASES 9175 \| MAP3K13 \| DISEASES 10923 \| SUB1 \| DISEASES 1462 \| VCAN \| DISEASES 1950 \| EGF \| DISEASES 10371 \| SEMA3A \| DISEASES 7982 \| ST7 \| DISEASES 26229 \| B3GAT3 \| DISEASES 11234 \| HPS5 \| DISEASES 7078 \| TIMP3 \| DISEASES 5149 \| PDE6H \| DISEASES 347902 \| AMIGO2 \| DISEASES 4060 \| LUM \| DISEASES 11081 \| KERA \| DISEASES 50511 \| SYCP3 \| DISEASES 283375 \| SLC39A5 \| DISEASES 6252 \| RTN1 \| DISEASES 585 \| BBS4 \| DISEASES 170691 \| ADAMTS17 \| DISEASES 5373 \| PMM2 \| DISEASES 85407 \| NKD1 \| DISEASES 8996 \| NOL3 \| DISEASES 2588 \| GALNS \| DISEASES 2589 \| GALNT1 \| DISEASES 81794 \| ADAMTS10 \| DISEASES 6531 \| SLC6A3 \| DISEASES 1952 \| CELSR2 \| DISEASES 54507 \| ADAMTSL4 \| DISEASES 10637 \| LEFTY1 \| DISEASES 7483 \| WNT9A \| DISEASES 23500 \| DAAM2 \| DISEASES 2041 \| EPHA1 \| DISEASES 4851 \| NOTCH1 \| DISEASES 57689 \| LRRC4C \| DISEASES 6911 \| TBX6 \| DISEASES 23074 \| UHRF1BP1L \| DISEASES 22948 \| CCT5 \| DISEASES 51232 \| CRIM1 \| DISEASES 9871 \| SEC24D \| DISEASES 1420 \| CRYGC \| DISEASES 2893 \| GRIA4 \| DISEASES 25836 \| NIPBL \| DISEASES 29974 \| A1CF \| DISEASES 651 \| BMP3 \| DISEASES 3087 \| HHEX \| DISEASES 170692 \| ADAMTS18 \| DISEASES 5801 \| PTPRR \| DISEASES 760 \| CA2 \| DISEASES 1562 \| CYP2C18 \| DISEASES 54971 \| BANP \| DISEASES 7411 \| VBP1 \| DISEASES 157657 \| C8orf37 \| DISEASES 9530 \| BAG4 \| DISEASES 5147 \| PDE6D \| DISEASES 6529 \| SLC6A1 \| DISEASES 4681 \| NBL1 \| DISEASES 1142 \| CHRNB3 \| DISEASES 7484 \| WNT9B \| DISEASES 57369 \| GJD2 \| DISEASES 70 \| ACTC1 \| DISEASES 79190 \| IRX6 \| DISEASES 1409 \| CRYAA \| DISEASES 4041 \| LRP5 \| DISEASES 9965 \| FGF19 \| DISEASES 251 \| ALPPL2 \| DISEASES 6051 \| RNPEP \| DISEASES 166336 \| PRICKLE2 \| DISEASES 57619 \| SHROOM3 \| DISEASES 84343 \| HPS3 \| DISEASES 6010 \| RHO \| DISEASES 149461 \| CLDN19 \| DISEASES 85409 \| NKD2 \| DISEASES 6469 \| SHH \| DISEASES 22853 \| LMTK2 \| DISEASES 79698 \| ZMAT4 \| DISEASES 115825 \| WDFY2 \| DISEASES 401 \| PHOX2A \| DISEASES 90167 \| FRMD7 \| DISEASES 282974 \| STK32C \| DISEASES 9317 \| PTER \| DISEASES 81693 \| AMN \| DISEASES 55832 \| CAND1 \| DISEASES 1381 \| CRABP1 \| DISEASES 9150 \| CTDP1 \| DISEASES 4314 \| MMP3 \| DISEASES 26585 \| GREM1 \| DISEASES 558 \| AXL \| DISEASES 50964 \| SOST \| DISEASES 54442 \| KCTD5 \| DISEASES 9427 \| ECEL1 \| DISEASES 27166 \| PRELID1 \| DISEASES 81603 \| TRIM8 \| DISEASES 9839 \| ZEB2 \| DISEASES 3479 \| IGF1 \| DISEASES 10296 \| MAEA \| DISEASES 10251 \| SPRY3 \| DISEASES 5308 \| PITX2 \| DISEASES 136 \| ADORA2B \| DISEASES 10736 \| SIX2 \| DISEASES 260425 \| MAGI3 \| DISEASES 375611 \| SLC26A5 \| DISEASES 1841 \| DTYMK \| DISEASES 25928 \| SOSTDC1 \| DISEASES 8419 \| BFSP2 \| DISEASES 79192 \| IRX1 \| DISEASES 84342 \| COG8 \| DISEASES 23450 \| SF3B3 \| DISEASES 1296 \| COL8A2 \| DISEASES 378 \| ARF4 \| DISEASES 1816 \| DRD5 \| DISEASES 2353 \| FOS \| DISEASES 1128 \| CHRM1 \| DISEASES 153572 \| IRX2 \| DISEASES 1501 \| CTNND2 \| DISEASES 113189 \| CHST14 \| DISEASES 5859 \| QARS \| DISEASES 54205 \| CYCS \| DISEASES 5340 \| PLG \| DISEASES 29925 \| GMPPB \| DISEASES 54715 \| RBFOX1 \| DISEASES 26502 \| NARF \| DISEASES 81839 \| VANGL1 \| DISEASES 137735 \| ABRA \| DISEASES 1605 \| DAG1 \| DISEASES 254102 \| EHBP1L1 \| DISEASES 84440 \| RAB11FIP4 \| DISEASES 23262 \| PPIP5K2 \| DISEASES 8636 \| SSNA1 \| DISEASES 10692 \| RRH \| DISEASES 9129 \| PRPF3 \| DISEASES 9495 \| AKAP5 \| DISEASES 29926 \| GMPPA \| DISEASES 1604 \| CD55 \| DISEASES 9229 \| DLGAP1 \| DISEASES 54714 \| CNGB3 \| DISEASES 6950 \| TCP1 \| DISEASES 582 \| BBS1 \| DISEASES 55620 \| STAP2 \| DISEASES 64388 \| GREM2 \| DISEASES 6764 \| ST5 \| DISEASES 1129 \| CHRM2 \| DISEASES 11145 \| PLA2G16 \| DISEASES 10938 \| EHD1 \| DISEASES 115752 \| DIS3L \| DISEASES 205 \| AK4 \| DISEASES 4312 \| MMP1 \| DISEASES 51010 \| EXOSC3 \| DISEASES 199699 \| DAND5 \| DISEASES 4642 \| MYO1D \| DISEASES 3909 \| LAMA3 \| DISEASES 57010 \| CABP4 \| DISEASES 29895 \| MYLPF \| DISEASES 55486 \| PARL \| DISEASES 157807 \| CLVS1 \| DISEASES 7481 \| WNT11 \| DISEASES 2200 \| FBN1 \| DISEASES 57716 \| PRX \| DISEASES 2303 \| FOXC2 \| DISEASES 79147 \| FKRP \| DISEASES 633 \| BGN \| DISEASES 284359 \| IZUMO1 \| DISEASES 7050 \| TGIF1 \| DISEASES 56478 \| EIF4ENIF1 \| DISEASES 9241 \| NOG \| DISEASES 1260 \| CNGA2 \| DISEASES 4990 \| SIX6 \| DISEASES 286753 \| TUSC5 \| DISEASES 221692 \| PHACTR1 \| DISEASES 80176 \| SPSB1 \| DISEASES 4496 \| MT1H \| DISEASES 2192 \| FBLN1 \| DISEASES 1538 \| CYLC1 \| DISEASES 79191 \| IRX3 \| DISEASES 3212 \| HOXB2 \| DISEASES 9573 \| GDF3 \| DISEASES 29940 \| DSE \| DISEASES 222546 \| RFX6 \| DISEASES 220 \| ALDH1A3 \| DISEASES 5915 \| RARB \| DISEASES 2689 \| GH2 \| DISEASES 668 \| FOXL2 \| DISEASES 9877 \| ZC3H11A \| DISEASES 3751 \| KCND2 \| DISEASES 25794 \| FSCN2 \| DISEASES 55589 \| BMP2K \| DISEASES 342035 \| GLDN \| DISEASES 55217 \| TMLHE \| DISEASES 135 \| ADORA2A \| DISEASES 84146 \| ZNF644 \| DISEASES 9227 \| LRAT \| DISEASES 4842 \| NOS1 \| DISEASES 3932 \| LCK \| DISEASES 64412 \| GZF1 \| DISEASES 6622 \| SNCA \| DISEASES 64778 \| FNDC3B \| DISEASES 6540 \| SLC6A13 \| DISEASES 4521 \| NUDT1 \| DISEASES 23275 \| POFUT2 \| DISEASES 221927 \| BRAT1 \| DISEASES 60506 \| NYX \| DISEASES 401138 \| AMTN \| DISEASES 3167 \| HMX2 \| DISEASES 27098 \| CLUL1 \| DISEASES 388228 \| SBK1 \| DISEASES 124454 \| EARS2 \| DISEASES 5549 \| PRELP \| DISEASES 1499 \| CTNNB1 \| DISEASES 84075 \| FSCB \| DISEASES 4771 \| NF2 \| DISEASES 56479 \| KCNQ5 \| DISEASES 440435 \| GPR179 \| DISEASES 144165 \| PRICKLE1 \| DISEASES 56940 \| DUSP22 \| DISEASES 22881 \| ANKRD6 \| DISEASES 8326 \| FZD9 \| DISEASES 6890 \| TAP1 \| DISEASES 54716 \| SLC6A20 \| DISEASES 1413 \| CRYBA4 \| DISEASES 2331 \| FMOD \| DISEASES 80781 \| COL18A1 \| DISEASES 10142 \| AKAP9 \| DISEASES 51256 \| TBC1D7 \| DISEASES 8736 \| MYOM1 \| DISEASES 284654 \| RSPO1 \| DISEASES 723961 \| INS-IGF2 \| DISEASES 55124 \| PIWIL2 \| DISEASES 23513 \| SCRIB \| DISEASES 1297 \| COL9A1 \| DISEASES 9961 \| MVP \| DISEASES 4763 \| NF1 \| DISEASES 157680 \| VPS13B \| DISEASES 8323 \| FZD6 \| DISEASES 56980 \| PRDM10 \| DISEASES 8822 \| FGF17 \| DISEASES 5995 \| RGR \| DISEASES 6942 \| TCF20 \| DISEASES 653440 \| WASH6P \| DISEASES 6539 \| SLC6A12 \| DISEASES 7456 \| WIPF1 \| DISEASES 79947 \| DHDDS \| DISEASES 11169 \| WDHD1 \| DISEASES 22909 \| FAN1 \| DISEASES 9760 \| TOX \| DISEASES 55605 \| KIF21A \| DISEASES 56853 \| CELF4 \| DISEASES 3211 \| HOXB1 \| DISEASES 5891 \| MOK \| DISEASES 1527 \| TEX28 \| DISEASES 1122 \| CHML \| DISEASES 148789 \| B3GALNT2 \| DISEASES 6905 \| TBCE \| DISEASES 127018 \| LYPLAL1 \| DISEASES 7042 \| TGFB2 \| DISEASES 26254 \| OPTC \| DISEASES 7432 \| VIP \| DISEASES 23418 \| CRB1 \| DISEASES 10090 \| UST \| DISEASES 1660 \| DHX9 \| DISEASES 1805 \| DPT \| DISEASES 1490 \| CTGF \| DISEASES 57216 \| VANGL2 \| DISEASES 5824 \| PEX19 \| DISEASES 93183 \| PIGM \| DISEASES 3645 \| INSRR \| DISEASES 6232 \| RPS27 \| DISEASES 4942 \| OAT \| DISEASES 7286 \| TUFT1 \| DISEASES 1193 \| CLIC2 \| DISEASES 116442 \| RAB39B \| DISEASES 65991 \| FUNDC2 \| DISEASES 8266 \| UBL4A \| DISEASES 7482 \| WNT2B \| DISEASES 140 \| ADORA3 \| DISEASES 5016 \| OVGP1 \| DISEASES 3744 \| KCNA10 \| DISEASES 167691 \| LCA5 \| DISEASES 2316 \| FLNA \| DISEASES 728447 \| TEX28P1 \| DISEASES 2652 \| OPN1MW \| DISEASES 653363 \| TEX28P2 \| DISEASES 5956 \| OPN1LW \| DISEASES 1301 \| COL11A1 \| DISEASES 1810 \| DR1 \| DISEASES 79057 \| PRRG3 \| DISEASES 4534 \| MTM1 \| DISEASES 2258 \| FGF13 \| DISEASES 5737 \| PTGFR \| DISEASES 653 \| BMP5 \| DISEASES 23401 \| FRAT2 \| DISEASES 10023 \| FRAT1 \| DISEASES 9124 \| PDLIM1 \| DISEASES 26027 \| ACOT11 \| DISEASES 202500 \| TCTE1 \| DISEASES 7319 \| UBE2A \| DISEASES 286257 \| C9orf142 \| DISEASES 1289 \| COL5A1 \| DISEASES 51727 \| CMPK1 \| DISEASES 6834 \| SURF1 \| DISEASES 55624 \| POMGNT1 \| DISEASES 7422 \| VEGFA \| DISEASES 94233 \| OPN4 \| DISEASES 27069 \| GHITM \| DISEASES 10585 \| POMT1 \| DISEASES 23404 \| EXOSC2 \| DISEASES 11128 \| POLR3A \| DISEASES 7075 \| TIE1 \| DISEASES 1907 \| EDN2 \| DISEASES 1298 \| COL9A2 \| DISEASES 656 \| BMP8B \| DISEASES 26508 \| HEYL \| DISEASES 1025 \| CDK9 \| DISEASES 50945 \| TBX22 \| DISEASES 23633 \| KPNA6 \| DISEASES 80114 \| BICC1 \| DISEASES 11130 \| ZWINT \| DISEASES 6015 \| RING1 \| DISEASES 1302 \| COL11A2 \| DISEASES 1306 \| COL15A1 \| DISEASES 3055 \| HCK \| DISEASES 7918 \| GPANK1 \| DISEASES 778 \| CACNA1F \| DISEASES 7546 \| ZIC2 \| DISEASES 23348 \| DOCK9 \| DISEASES 30813 \| VSX1 \| DISEASES 1325 \| CORT \| DISEASES 56998 \| CTNNBIP1 \| DISEASES 631 \| BFSP1 \| DISEASES 2857 \| GPR34 \| DISEASES 120863 \| DEPDC4 \| DISEASES 6103 \| RPGR \| DISEASES 2189 \| FANCG \| DISEASES 650 \| BMP2 \| DISEASES 64225 \| ATL2 \| DISEASES 646480 \| FABP9 \| DISEASES 5080 \| PAX6 \| DISEASES 55973 \| BCAP29 \| DISEASES 5251 \| PHEX \| DISEASES 345193 \| LRIT3 \| DISEASES 241 \| ALOX5AP \| DISEASES 1280 \| COL2A1 \| DISEASES 4676 \| NAP1L4 \| DISEASES 6456 \| SH3GL2 \| DISEASES 2296 \| FOXC1 \| DISEASES 9350 \| CER1 \| DISEASES 8777 \| MPDZ \| DISEASES 7054 \| TH \| DISEASES 6453 \| ITSN1 \| DISEASES 9946 \| CRYZL1 \| DISEASES 50808 \| AK3 \| DISEASES 143 \| PARP4 \| DISEASES 114899 \| C1QTNF3 \| DISEASES 169522 \| KCNV2 \| DISEASES 387911 \| C1QTNF9B \| DISEASES 4285 \| MIPEP \| DISEASES 94137 \| RP1L1 \| DISEASES 1186 \| CLCN7 \| DISEASES 361 \| AQP4 \| DISEASES 1133 \| CHRM5 \| DISEASES 55576 \| STAB2 \| DISEASES 56953 \| NT5M \| DISEASES 238 \| ALK \| DISEASES 4017 \| LOXL2 \| DISEASES 1146 \| CHRNG \| DISEASES 284217 \| LAMA1 \| DISEASES 11340 \| EXOSC8 \| DISEASES 2524 \| FUT2 \| DISEASES 9244 \| CRLF1 \| DISEASES 29994 \| BAZ2B \| DISEASES 51651 \| PTRH2 \| DISEASES 6430 \| SRSF5 \| DISEASES 3426 \| CFI \| DISEASES 26022 \| TMEM98 \| DISEASES 5530 \| PPP3CA \| DISEASES 64115 \| C10orf54 \| DISEASES 4145 \| MATK \| DISEASES 6046 \| BRD2 \| DISEASES 4239 \| MFAP4 \| DISEASES 6641 \| SNTB1 \| DISEASES 6235 \| RPS29 \| DISEASES 137872 \| ADHFE1 \| DISEASES 4901 \| NRL \| DISEASES 4308 \| TRPM1 \| DISEASES 64221 \| ROBO3 \| DISEASES 1415 \| CRYBB2 \| DISEASES 7110 \| TMF1 \| DISEASES 81539 \| SLC38A1 \| DISEASES 84570 \| COL25A1 \| DISEASES 54890 \| ALKBH5 \| DISEASES 55698 \| RADIL \| DISEASES 10581 \| IFITM2 \| DISEASES 100463285 \| MTRNR2L4 \| DISEASES 57096 \| RPGRIP1 \| DISEASES 84189 \| SLITRK6 \| DISEASES 4148 \| MATN3 \| DISEASES 643418 \| LIPN \| DISEASES 23077 \| MYCBP2 \| DISEASES 285016 \| FAM150B \| DISEASES 51701 \| NLK \| DISEASES 9378 \| NRXN1 \| DISEASES 137970 \| UNC5D \| DISEASES 3778 \| KCNMA1 \| DISEASES 2570 \| GABRR2 \| DISEASES 55777 \| MBD5 \| DISEASES 89766 \| UMODL1 \| DISEASES 1123 \| CHN1 \| DISEASES 176 \| ACAN \| DISEASES 2641 \| GCG \| DISEASES 348180 \| CTU2 \| DISEASES 10321 \| CRISP3 \| DISEASES 388336 \| SHISA6 \| DISEASES 285175 \| UNC80 \| DISEASES 55657 \| ZNF692 \| DISEASES 83552 \| MFRP \| DISEASES 3481 \| IGF2 \| DISEASES 55636 \| CHD7 \| DISEASES 6399 \| TRAPPC2 \| DISEASES 6222 \| RPS18 \| DISEASES 23210 \| JMJD6 \| DISEASES 1029 \| CDKN2A \| DISEASES 23705 \| CADM1 \| DISEASES 5076 \| PAX2 \| DISEASES 8823 \| FGF16 \| DISEASES 139716 \| GAB3 \| DISEASES 7439 \| BEST1 \| DISEASES 3908 \| LAMA2 \| DISEASES 84627 \| ZNF469 \| DISEASES 8315 \| BRAP \| DISEASES 197320 \| ZNF778 \| DISEASES 139728 \| PNCK \| DISEASES 5923 \| RASGRF1 \| DISEASES 9742 \| IFT140 \| DISEASES 399697 \| CTXN2 \| DISEASES 84897 \| TBRG1 \| DISEASES 1132 \| CHRM4 \| DISEASES 2263 \| FGFR2 \| DISEASES 84319 \| CMSS1 \| DISEASES 89782 \| LMLN \| DISEASES 116 \| ADCYAP1 \| DISEASES 2569 \| GABRR1 \| DISEASES 161823 \| ADAL \| DISEASES 404672 \| GTF2H5 \| DISEASES 7045 \| TGFBI \| DISEASES 10682 \| EBP \| DISEASES 1539 \| CYLC2 \| DISEASES 5890 \| RAD51B \| DISEASES 6256 \| RXRA \| DISEASES 4345 \| CD200 \| DISEASES 6091 \| ROBO1 \| DISEASES 5542 \| PRB1 \| DISEASES 4043 \| LRPAP1 \| DISEASES 346007 \| EYS \| DISEASES 342538 \| NACA2 \| DISEASES 3347 \| HTN3 \| DISEASES 8322 \| FZD4 \| DISEASES 7164 \| TPD52L1 \| DISEASES 9973 \| CCS \| DISEASES 100463289 \| MTRNR2L5 \| DISEASES 84133 \| ZNRF3 \| DISEASES 80184 \| CEP290 \| DISEASES 8499 \| PPFIA2 \| DISEASES 10381 \| TUBB3 \| DISEASES 414899 \| BLID \| DISEASES 4212 \| MEIS2 \| DISEASES 820 \| CAMP \| DISEASES 7716 \| VEZF1 \| DISEASES 4782 \| NFIC \| DISEASES 3292 \| HSD17B1 \| DISEASES 200959 \| GABRR3 \| DISEASES 54938 \| SARS2 \| DISEASES 57000 \| GSN-AS1 \| DISEASES 102723508 \| KANTR \| DISEASES 348120 \| LINC01193 \| DISEASES 26766 \| RNU105C \| DISEASES 6080 \| SNORA73A \| DISEASES 26770 \| SNORD79 \| DISEASES 25826 \| SNORD82 \| DISEASES 347689 \| SOX2-OT \| DISEASES
Locus	(Waiting for update.)

Disease ID	837
Disease	refractive error
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:39) HP:0000505 \| Poor vision \| 26 HP:0000545 \| Near sightedness \| 22 HP:0000540 \| Hypermetropia \| 11 HP:0000618 \| Blindness \| 10 HP:0000646 \| Wandering eyes \| 8 HP:0000518 \| Cataract \| 7 HP:0000483 \| Astigmatism \| 6 HP:0011003 \| High myopia \| 5 HP:0007868 \| ARMD \| 4 HP:0000563 \| Conical cornea \| 4 HP:0000572 \| Visual loss \| 4 HP:0000565 \| Inward turning of one or both eyes \| 4 HP:0000501 \| Glaucoma \| 3 HP:0100021 \| Cerebral palsy \| 2 HP:0000486 \| Squint eyes \| 2 HP:0000365 \| Hearing impairment \| 2 HP:0002315 \| Headaches \| 2 HP:0000639 \| Nystagmus \| 2 HP:0000488 \| Noninflammatory retina disease \| 2 HP:0000510 \| Retinitis pigmentosa \| 2 HP:0012803 \| Anisometropia \| 2 HP:0000609 \| Optic nerve hypoplasia \| 1 HP:0005306 \| Capillary hemangioma \| 1 HP:0007957 \| Corneal clouding \| 1 HP:0002172 \| Postural instability \| 1 HP:0007018 \| Attention deficits \| 1 HP:0001123 \| Partial loss of field of vision \| 1 HP:0006934 \| Congenital nystagmus \| 1 HP:0007802 \| Granular corneal dystrophy \| 1 HP:0007687 \| Unilateral ptosis \| 1 HP:0007970 \| Congenital ptosis \| 1 HP:0000717 \| Autism \| 1 HP:0000708 \| Behavioral problems \| 1 HP:0001131 \| Corneal dystrophy \| 1 HP:0000508 \| Drooping upper eyelid \| 1 HP:0001059 \| Pterygium \| 1 HP:0002076 \| Migraine headaches \| 1 HP:0002167 \| Speech disorder \| 1 HP:0000752 \| Hyperactive behavior \| 1

Disease ID	837
Disease	refractive error
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:2) C0456909 \| blindness \| 10 C0002418 \| amblyopia \| 8

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:38)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs104893768	11879142	4901	NRL	umls:C0034951	BeFree	The dark-adaptation thresholds, equivalent visual field diameters, and electroretinogram amplitudes (all corrected for age and refractive error) indicated that the disease caused by the NRL mutations was more severe than that caused by the dominant rhodopsin mutation Pro23His and was similar in severity to that produced by the rhodopsin mutation Pro347Leu.	0.000271442	2002	RHO	3	129528801	C	A
rs104893768	11879142	6010	RHO	umls:C0034951	BeFree	The dark-adaptation thresholds, equivalent visual field diameters, and electroretinogram amplitudes (all corrected for age and refractive error) indicated that the disease caused by the NRL mutations was more severe than that caused by the dominant rhodopsin mutation Pro23His and was similar in severity to that produced by the rhodopsin mutation Pro347Leu.	0.000271442	2002	RHO	3	129528801	C	A
rs10500355	23474815	54715	RBFOX1	umls:C0034951	GWASCAT	Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error.	0.120271442	2014	RBFOX1	16	7409346	T	A
rs11145465	23396134	9414	TJP2	umls:C0034951	GWASCAT	Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.	0.12	2013	TJP2	9	69151677	C	A
rs11601239	23396134	2893	GRIA4	umls:C0034951	GWASCAT	Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.	0.12	2013	GRIA4	11	105685872	C	G
rs12205363	23396134	3908	LAMA2	umls:C0034951	GWASCAT	Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.	0.12	2013	LAMA2;LOC102723409	6	129513484	T	C
rs12229663	23396134	5801	PTPRR	umls:C0034951	GWASCAT	Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.	0.12	2013	PTPRR	12	70856216	A	G
rs1254319	23396134	317761	C14orf39	umls:C0034951	GWASCAT	Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.	0.12	2013	C14orf39	14	60437039	G	A
rs12971120	23396134	55748	CNDP2	umls:C0034951	GWASCAT	Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.	0.12	2013	CNDP2	18	74506788	A	G
rs14165	23396134	776	CACNA1D	umls:C0034951	GWASCAT	Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.	0.12	2013	CACNA1D	3	53813381	A	G
rs17183295	23396134	4642	MYO1D	umls:C0034951	GWASCAT	Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.	0.12	2013	MYO1D	17	32751254	C	T
rs17648524	23396134	54715	RBFOX1	umls:C0034951	GWASCAT	Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.	0.120271442	2013	RBFOX1	16	7409682	G	C
rs1881492	23396134	1146	CHRNG	umls:C0034951	GWASCAT	Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.	0.12	2013	CHRNG	2	232542288	T	G
rs2137277	24014484	6422	SFRP1	umls:C0034951	BeFree	Three genetic loci SHISA6-DNAH9, GJD2 and ZMAT4-SFRP1 exhibited a strong association with myopic refractive error in individuals with higher secondary or university education (SHISA6-DNAH9: rs2969180 A allele, β = -0.33 D, P = 3.6 × 10(-6); GJD2: rs524952 A allele, β = -0.31 D, P = 1.68 × 10(-5); ZMAT4-SFRP1: rs2137277 A allele, β = -0.47 D, P = 1.68 × 10(-4)), whereas the association at these loci was non-significant or of borderline significance in those with lower secondary education or below (P for interaction: 3.82 × 10(-3)-4.78 × 10(-4)).	0.000271442	2014	ZMAT4	8	40877143	A	G,T
rs2137277	24014484	79698	ZMAT4	umls:C0034951	BeFree	Three genetic loci SHISA6-DNAH9, GJD2 and ZMAT4-SFRP1 exhibited a strong association with myopic refractive error in individuals with higher secondary or university education (SHISA6-DNAH9: rs2969180 A allele, β = -0.33 D, P = 3.6 × 10(-6); GJD2: rs524952 A allele, β = -0.31 D, P = 1.68 × 10(-5); ZMAT4-SFRP1: rs2137277 A allele, β = -0.47 D, P = 1.68 × 10(-4)), whereas the association at these loci was non-significant or of borderline significance in those with lower secondary education or below (P for interaction: 3.82 × 10(-3)-4.78 × 10(-4)).	0.120271442	2014	ZMAT4	8	40877143	A	G,T
rs2137277	24014484	1770	DNAH9	umls:C0034951	BeFree	Three genetic loci SHISA6-DNAH9, GJD2 and ZMAT4-SFRP1 exhibited a strong association with myopic refractive error in individuals with higher secondary or university education (SHISA6-DNAH9: rs2969180 A allele, β = -0.33 D, P = 3.6 × 10(-6); GJD2: rs524952 A allele, β = -0.31 D, P = 1.68 × 10(-5); ZMAT4-SFRP1: rs2137277 A allele, β = -0.47 D, P = 1.68 × 10(-4)), whereas the association at these loci was non-significant or of borderline significance in those with lower secondary education or below (P for interaction: 3.82 × 10(-3)-4.78 × 10(-4)).	0.000271442	2014	ZMAT4	8	40877143	A	G,T
rs2137277	24014484	388336	SHISA6	umls:C0034951	BeFree	Three genetic loci SHISA6-DNAH9, GJD2 and ZMAT4-SFRP1 exhibited a strong association with myopic refractive error in individuals with higher secondary or university education (SHISA6-DNAH9: rs2969180 A allele, β = -0.33 D, P = 3.6 × 10(-6); GJD2: rs524952 A allele, β = -0.31 D, P = 1.68 × 10(-5); ZMAT4-SFRP1: rs2137277 A allele, β = -0.47 D, P = 1.68 × 10(-4)), whereas the association at these loci was non-significant or of borderline significance in those with lower secondary education or below (P for interaction: 3.82 × 10(-3)-4.78 × 10(-4)).	0.120271442	2014	ZMAT4	8	40877143	A	G,T
rs2137277	24014484	57369	GJD2	umls:C0034951	BeFree	Three genetic loci SHISA6-DNAH9, GJD2 and ZMAT4-SFRP1 exhibited a strong association with myopic refractive error in individuals with higher secondary or university education (SHISA6-DNAH9: rs2969180 A allele, β = -0.33 D, P = 3.6 × 10(-6); GJD2: rs524952 A allele, β = -0.31 D, P = 1.68 × 10(-5); ZMAT4-SFRP1: rs2137277 A allele, β = -0.47 D, P = 1.68 × 10(-4)), whereas the association at these loci was non-significant or of borderline significance in those with lower secondary education or below (P for interaction: 3.82 × 10(-3)-4.78 × 10(-4)).	0.120271442	2014	ZMAT4	8	40877143	A	G,T
rs2184971	23396134	5095	PCCA	umls:C0034951	GWASCAT	Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.	0.12	2013	PCCA	13	100165838	A	G
rs29001566	11879142	4901	NRL	umls:C0034951	BeFree	The dark-adaptation thresholds, equivalent visual field diameters, and electroretinogram amplitudes (all corrected for age and refractive error) indicated that the disease caused by the NRL mutations was more severe than that caused by the dominant rhodopsin mutation Pro23His and was similar in severity to that produced by the rhodopsin mutation Pro347Leu.	0.000271442	2002	RHO	3	129533711	C	A,G,T
rs29001566	11879142	6010	RHO	umls:C0034951	BeFree	The dark-adaptation thresholds, equivalent visual field diameters, and electroretinogram amplitudes (all corrected for age and refractive error) indicated that the disease caused by the NRL mutations was more severe than that caused by the dominant rhodopsin mutation Pro23His and was similar in severity to that produced by the rhodopsin mutation Pro347Leu.	0.000271442	2002	RHO	3	129533711	C	A,G,T
rs2969180	24014484	6422	SFRP1	umls:C0034951	BeFree	Three genetic loci SHISA6-DNAH9, GJD2 and ZMAT4-SFRP1 exhibited a strong association with myopic refractive error in individuals with higher secondary or university education (SHISA6-DNAH9: rs2969180 A allele, β = -0.33 D, P = 3.6 × 10(-6); GJD2: rs524952 A allele, β = -0.31 D, P = 1.68 × 10(-5); ZMAT4-SFRP1: rs2137277 A allele, β = -0.47 D, P = 1.68 × 10(-4)), whereas the association at these loci was non-significant or of borderline significance in those with lower secondary education or below (P for interaction: 3.82 × 10(-3)-4.78 × 10(-4)).	0.000271442	2014	SHISA6	17	11504584	G	A
rs2969180	24014484	388336	SHISA6	umls:C0034951	BeFree	Three genetic loci SHISA6-DNAH9, GJD2 and ZMAT4-SFRP1 exhibited a strong association with myopic refractive error in individuals with higher secondary or university education (SHISA6-DNAH9: rs2969180 A allele, β = -0.33 D, P = 3.6 × 10(-6); GJD2: rs524952 A allele, β = -0.31 D, P = 1.68 × 10(-5); ZMAT4-SFRP1: rs2137277 A allele, β = -0.47 D, P = 1.68 × 10(-4)), whereas the association at these loci was non-significant or of borderline significance in those with lower secondary education or below (P for interaction: 3.82 × 10(-3)-4.78 × 10(-4)).	0.120271442	2014	SHISA6	17	11504584	G	A
rs2969180	24014484	1770	DNAH9	umls:C0034951	BeFree	Three genetic loci SHISA6-DNAH9, GJD2 and ZMAT4-SFRP1 exhibited a strong association with myopic refractive error in individuals with higher secondary or university education (SHISA6-DNAH9: rs2969180 A allele, β = -0.33 D, P = 3.6 × 10(-6); GJD2: rs524952 A allele, β = -0.31 D, P = 1.68 × 10(-5); ZMAT4-SFRP1: rs2137277 A allele, β = -0.47 D, P = 1.68 × 10(-4)), whereas the association at these loci was non-significant or of borderline significance in those with lower secondary education or below (P for interaction: 3.82 × 10(-3)-4.78 × 10(-4)).	0.000271442	2014	SHISA6	17	11504584	G	A
rs2969180	23396134	388336	SHISA6	umls:C0034951	GWASCAT	Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.	0.120271442	2013	SHISA6	17	11504584	G	A
rs2969180	24014484	79698	ZMAT4	umls:C0034951	BeFree	Three genetic loci SHISA6-DNAH9, GJD2 and ZMAT4-SFRP1 exhibited a strong association with myopic refractive error in individuals with higher secondary or university education (SHISA6-DNAH9: rs2969180 A allele, β = -0.33 D, P = 3.6 × 10(-6); GJD2: rs524952 A allele, β = -0.31 D, P = 1.68 × 10(-5); ZMAT4-SFRP1: rs2137277 A allele, β = -0.47 D, P = 1.68 × 10(-4)), whereas the association at these loci was non-significant or of borderline significance in those with lower secondary education or below (P for interaction: 3.82 × 10(-3)-4.78 × 10(-4)).	0.120271442	2014	SHISA6	17	11504584	G	A
rs2969180	24014484	57369	GJD2	umls:C0034951	BeFree	Three genetic loci SHISA6-DNAH9, GJD2 and ZMAT4-SFRP1 exhibited a strong association with myopic refractive error in individuals with higher secondary or university education (SHISA6-DNAH9: rs2969180 A allele, β = -0.33 D, P = 3.6 × 10(-6); GJD2: rs524952 A allele, β = -0.31 D, P = 1.68 × 10(-5); ZMAT4-SFRP1: rs2137277 A allele, β = -0.47 D, P = 1.68 × 10(-4)), whereas the association at these loci was non-significant or of borderline significance in those with lower secondary education or below (P for interaction: 3.82 × 10(-3)-4.78 × 10(-4)).	0.120271442	2014	SHISA6	17	11504584	G	A
rs3138144	23396134	100528022	BLOC1S1-RDH5	umls:C0034951	GWASCAT	Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.	0.12	2013	RDH5;BLOC1S1-RDH5	12	55720985	G	C
rs4778879	23396134	5923	RASGRF1	umls:C0034951	GWASCAT	Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.	0.24	2013	RASGRF1	15	79080533	A	G
rs524952	24014484	1770	DNAH9	umls:C0034951	BeFree	Three genetic loci SHISA6-DNAH9, GJD2 and ZMAT4-SFRP1 exhibited a strong association with myopic refractive error in individuals with higher secondary or university education (SHISA6-DNAH9: rs2969180 A allele, β = -0.33 D, P = 3.6 × 10(-6); GJD2: rs524952 A allele, β = -0.31 D, P = 1.68 × 10(-5); ZMAT4-SFRP1: rs2137277 A allele, β = -0.47 D, P = 1.68 × 10(-4)), whereas the association at these loci was non-significant or of borderline significance in those with lower secondary education or below (P for interaction: 3.82 × 10(-3)-4.78 × 10(-4)).	0.000271442	2014	NA	15	34713685	T	A
rs524952	24014484	6422	SFRP1	umls:C0034951	BeFree	Three genetic loci SHISA6-DNAH9, GJD2 and ZMAT4-SFRP1 exhibited a strong association with myopic refractive error in individuals with higher secondary or university education (SHISA6-DNAH9: rs2969180 A allele, β = -0.33 D, P = 3.6 × 10(-6); GJD2: rs524952 A allele, β = -0.31 D, P = 1.68 × 10(-5); ZMAT4-SFRP1: rs2137277 A allele, β = -0.47 D, P = 1.68 × 10(-4)), whereas the association at these loci was non-significant or of borderline significance in those with lower secondary education or below (P for interaction: 3.82 × 10(-3)-4.78 × 10(-4)).	0.000271442	2014	NA	15	34713685	T	A
rs524952	24014484	388336	SHISA6	umls:C0034951	BeFree	Three genetic loci SHISA6-DNAH9, GJD2 and ZMAT4-SFRP1 exhibited a strong association with myopic refractive error in individuals with higher secondary or university education (SHISA6-DNAH9: rs2969180 A allele, β = -0.33 D, P = 3.6 × 10(-6); GJD2: rs524952 A allele, β = -0.31 D, P = 1.68 × 10(-5); ZMAT4-SFRP1: rs2137277 A allele, β = -0.47 D, P = 1.68 × 10(-4)), whereas the association at these loci was non-significant or of borderline significance in those with lower secondary education or below (P for interaction: 3.82 × 10(-3)-4.78 × 10(-4)).	0.120271442	2014	NA	15	34713685	T	A
rs524952	24014484	79698	ZMAT4	umls:C0034951	BeFree	Three genetic loci SHISA6-DNAH9, GJD2 and ZMAT4-SFRP1 exhibited a strong association with myopic refractive error in individuals with higher secondary or university education (SHISA6-DNAH9: rs2969180 A allele, β = -0.33 D, P = 3.6 × 10(-6); GJD2: rs524952 A allele, β = -0.31 D, P = 1.68 × 10(-5); ZMAT4-SFRP1: rs2137277 A allele, β = -0.47 D, P = 1.68 × 10(-4)), whereas the association at these loci was non-significant or of borderline significance in those with lower secondary education or below (P for interaction: 3.82 × 10(-3)-4.78 × 10(-4)).	0.120271442	2014	NA	15	34713685	T	A
rs524952	24014484	57369	GJD2	umls:C0034951	BeFree	Three genetic loci SHISA6-DNAH9, GJD2 and ZMAT4-SFRP1 exhibited a strong association with myopic refractive error in individuals with higher secondary or university education (SHISA6-DNAH9: rs2969180 A allele, β = -0.33 D, P = 3.6 × 10(-6); GJD2: rs524952 A allele, β = -0.31 D, P = 1.68 × 10(-5); ZMAT4-SFRP1: rs2137277 A allele, β = -0.47 D, P = 1.68 × 10(-4)), whereas the association at these loci was non-significant or of borderline significance in those with lower secondary education or below (P for interaction: 3.82 × 10(-3)-4.78 × 10(-4)).	0.120271442	2014	NA	15	34713685	T	A
rs634990	20835239	440270	GOLGA8B	umls:C0034951	GAD	[A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14.]	0.002367032	2010	NA	15	34713872	T	C
rs7042950	23396134	6096	RORB	umls:C0034951	GWASCAT	Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.	0.12	2013	RORB	9	74534921	A	G
rs7744813	23396134	56479	KCNQ5	umls:C0034951	GWASCAT	Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.	0.12	2013	KCNQ5	6	72933566	C	A
rs7829127	23396134	79698	ZMAT4	umls:C0034951	GWASCAT	Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.	0.120271442	2013	ZMAT4	8	40868875	A	G

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:79)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
2	233379941	rs1656404	G	A	rs1656404	23396134	8.00E-11	NA	0.15	[0.11-0.20] unit decrease	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
2	233406998	rs1881492	T	G	rs1881492	23396134	5.00E-11	NA	0.14	[0.098-0.18] unit decrease	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
3	53847408	rs14165	A	G	rs14165	23396134	2.00E-08	NA	0.1	[0.063-0.129] unit increase	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
4	80530671	rs9307551	A	C	rs9307551	23396134	1.00E-08	NA	0.1	[0.066-0.132] unit decrease	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
4	81930814	rs1960445	C	T	rs1960445	23396134	1.00E-06	NA	0.11	[0.067-0.161] unit decrease	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
6	73643289	rs7744813	C	A	rs7744813	23396134	4.00E-09	NA	0.11	[0.075-0.149] unit increase	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
6	129834629	rs12205363	T	C	rs12205363	23396134	2.00E-12	NA	0.24	[0.17-0.3] unit increase	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
8	40726394	rs7829127	A	G	rs7829127	23396134	4.00E-10	NA	0.12	[0.081-0.151] unit increase	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
8	60179086	rs7837791	G	T	rs7837791	23396134	4.00E-12	NA	0.11	[0.077-0.135] unit increase	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
9	71766593	rs11145465	C	A	rs11145465	23396134	7.00E-09	NA	0.12	[0.083-0.165] unit decrease	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
9	77149837	rs7042950	A	G	rs7042950	23396134	4.00E-08	NA	0.1	[0.061-0.131] unit decrease	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
10	60265404	rs7084402	A	G	rs7084402	23396134	2.00E-13	NA	0.11	[0.079-0.137] unit decrease	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
10	94924324	rs10882165	A	T	rs10882165	23396134	1.00E-11	NA	0.11	[0.076-0.138] unit decrease	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
11	105556598	rs11601239	C	G	rs11601239	23396134	6.00E-09	NA	0.1	[0.064-0.126] unit decrease	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
12	56114769	rs3138144	G	C	rs3138144	23396134	4.00E-12	NA	0.12	[0.086-0.152] unit increase	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
12	71249996	rs12229663	A	G	rs12229663	23396134	5.00E-09	NA	0.1	[0.066-0.132] unit increase	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
13	100818092	rs2184971	A	G	rs2184971	23396134	2.00E-08	NA	0.09	[0.056-0.114] unit increase	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
14	60903757	rs1254319	G	A	rs1254319	23396134	1.00E-08	NA	0.09	[0.059-0.117] unit decrease	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
15	34989626	rs11073058	G	T	rs11073058	20835239	8.45E-12	NA	NA	NA	5,328 European descent individuals	European(5328)	ALL(5328)	EUR(5328)	ALL(5328)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Comparative Study
15	34989674	rs11073059	T	A	rs11073059	20835239	8.45E-12	NA	NA	NA	5,328 European descent individuals	European(5328)	ALL(5328)	EUR(5328)	ALL(5328)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Comparative Study
15	34989851	rs11073060	C	A	rs11073060	20835239	3.65E-12	NA	NA	NA	5,328 European descent individuals	European(5328)	ALL(5328)	EUR(5328)	ALL(5328)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Comparative Study
15	34990574	rs7163001	G	A	rs7163001	20835239	5.61E-12	NA	NA	NA	5,328 European descent individuals	European(5328)	ALL(5328)	EUR(5328)	ALL(5328)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Comparative Study
15	34991490	rs8032019	A	G	rs8032019	20835239	3.71E-10	NA	NA	NA	5,328 European descent individuals	European(5328)	ALL(5328)	EUR(5328)	ALL(5328)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Comparative Study
15	34994565	rs4924134	A	G	rs4924134	20835239	1.36E-12	NA	NA	NA	5,328 European descent individuals	European(5328)	ALL(5328)	EUR(5328)	ALL(5328)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Comparative Study
15	34995106	rs619788	C	A	rs619788	20835239	2.53E-11	NA	NA	NA	5,328 European descent individuals	European(5328)	ALL(5328)	EUR(5328)	ALL(5328)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Comparative Study
15	34998829	rs580839	G	A	rs580839	20835239	2.53E-11	NA	NA	NA	5,328 European descent individuals	European(5328)	ALL(5328)	EUR(5328)	ALL(5328)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Comparative Study
15	34998875	rs688220	G	A	rs688220	20835239	2.79E-11	NA	NA	NA	5,328 European descent individuals	European(5328)	ALL(5328)	EUR(5328)	ALL(5328)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Comparative Study
15	34999479	rs7176510	C	T	rs7176510	20835239	6.25E-11	NA	NA	NA	5,328 European descent individuals	European(5328)	ALL(5328)	EUR(5328)	ALL(5328)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Comparative Study
15	35000942	rs560766	G	A	rs560766	20835239	2.49E-11	NA	NA	NA	5,328 European descent individuals	European(5328)	ALL(5328)	EUR(5328)	ALL(5328)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Comparative Study
15	35005886	rs524952	T	A	rs524952	20835239	3.18E-14	NA	NA	NA	5,328 European descent individuals	European(5328)	ALL(5328)	EUR(5328)	ALL(5328)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Comparative Study
15	35005886	rs524952	T	A	rs524952	23396134	1.00E-15	NA	0.16	[0.12-0.2] unit decrease	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
15	35006073	rs634990	T	C	rs634990	20835239	2.00E-14	NA	0.23	[0.228-0.232] diopter increase	5,328 European descent individuals	European(5328)	ALL(5328)	EUR(5328)	ALL(5328)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	rs634990-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Comparative Study
15	35008335	rs685352	A	G	rs685352	20835239	4.19E-12	NA	NA	NA	5,328 European descent individuals	European(5328)	ALL(5328)	EUR(5328)	ALL(5328)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	Comparative Study
15	79372875	rs4778879	A	G	rs4778879	23396134	4.00E-11	NA	0.1	[0.073-0.131] unit decrease	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
15	79375347	rs6495367	G	A	rs6495367	20835236	3.86E-05	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	A	RASGRF1
15	79378821	rs13380104	C	T	rs13380104	20835236	4.42E-05	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	C	RASGRF1
15	79379492	rs1007365	T	G	rs1007365	20835236	4.77E-05	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	G	RASGRF1
15	79392548	rs2049176	A	C	rs2049176	20835236	2.54E-05	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	C	NA
15	79410710	rs2102999	T	C	rs2102999	20835236	1.95E-05	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	C	NA
15	79420245	rs8035606	C	T	rs8035606	20835236	2.06E-05	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	T	NA
15	79420620	rs1915726	C	G	rs1915726	20835236	3.69E-07	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	G	NA
15	79422726	rs8031638	C	T	rs8031638	20835236	4.48E-07	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	C	NA
15	79427260	rs8024813	A	G	rs8024813	20835236	3.93E-07	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	A	NA
15	79431063	rs939661	A	G	rs939661	20835236	2.73E-07	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	C	NA
15	79432359	rs12595749	A	G	rs12595749	20835236	6.39E-06	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	A	NA
15	79432475	rs11634679	T	C	rs11634679	20835236	3.83E-07	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	T	NA
15	79432737	rs11635757	T	C	rs11635757	20835236	3.83E-07	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	T	NA
15	79432992	rs11630571	C	A	rs11630571	20835236	3.82E-07	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	C	NA
15	79433171	rs12902831	G	A	rs12902831	20835236	3.82E-07	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	G	NA
15	79434787	rs11638625	T	G	rs11638625	20835236	3.96E-07	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	T	NA
15	79436192	rs11634903	A	G	rs11634903	20835236	3.94E-07	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	A	NA
15	79443363	rs4778924	T	C	rs4778924	20835236	3.34E-07	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	T	NA
15	79445816	rs11631411	C	T	rs11631411	20835236	3.34E-07	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	C	NA
15	79447810	rs4778651	G	A	rs4778651	20835236	9.81E-07	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	G	NA
15	79449335	rs2204069	A	G	rs2204069	20835236	1.00E-06	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	T	NA
15	79449627	rs12903747	A	C	rs12903747	20835236	1.01E-06	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	C	NA
15	79451869	rs939658	A	G	rs939658	20835236	2.00E-09	NA	0.15	[0.10-0.20] diopter decrease	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	rs939658-G	Comparative Study	T,C	NA
15	79455350	rs8033963	C	T	rs8033963	20835236	1.59E-07	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	T	NA
15	79456381	rs12439908	T	C	rs12439908	20835236	1.69E-07	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	T	NA
15	79457133	rs11629665	G	A	rs11629665	20835236	1.69E-07	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	A	NA
15	79458512	rs8031019	A	G	rs8031019	20835236	1.69E-07	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	G	NA
15	79458589	rs8031504	G	T	rs8031504	20835236	1.69E-07	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	G	NA
15	79461029	rs8027411	G	T	rs8027411	20835236	7.91E-08	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	G	NA
15	79461516	rs11072826	A	G	rs11072826	20835236	1.38E-07	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	A	NA
15	79463036	rs8038464	A	T	rs8038464	20835236	6.35E-06	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	T	NA
15	79463847	rs1474256	C	T	rs1474256	20835236	2.77E-06	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	C	NA
15	79463960	rs17175798	C	T	rs17175798	20835236	1.38E-07	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	C	NA
15	79465210	rs1434459	T	C	rs1434459	20835236	2.49E-06	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	A	NA
15	79465600	rs8024572	A	G	rs8024572	20835236	2.67E-06	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	A	NA
15	79465894	rs11634726	A	G	rs11634726	20835236	2.21E-06	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	A	NA
15	79468082	rs1560895	A	G	rs1560895	20835236	4.52E-05	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	C	NA
15	79470998	rs11072829	A	G	rs11072829	20835236	2.49E-06	NA	NA	NA	4,270 UK twins	UK(4270)	ALL(4270)	EUR(4270)	ALL(4270)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Comparative Study	A	NA
16	7459347	rs10500355	T	A	rs10500355	23474815	4.00E-09	NA	0.11	[0.074-0.147] unit decrease	6,597 European ancestry individuals; 683 Sardinian inidividuals	Sardinian(683)	European(6597)	ALL(7280)	EUR(7280)	ALL(7280)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908	refractive error	Eye disease	NA	Research Support, N.I.H., Extramural	Meta-Analysis
16	7459683	rs17648524	G	C	rs17648524	23396134	6.00E-10	NA	0.12	[0.081-0.155] unit decrease	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
17	11407901	rs2969180	G	A	rs2969180	23396134	7.00E-11	NA	0.1	[0.072-0.13] unit decrease	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
17	31078272	rs17183295	C	T	rs17183295	23396134	1.00E-10	NA	0.13	[0.092-0.17] unit decrease	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
17	68718734	rs4793501	C	T	rs4793501	23396134	3.00E-08	NA	0.08	[0.053-0.107] unit increase	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
18	72174023	rs12971120	A	G	rs12971120	23396134	2.00E-07	NA	0.1	[0.062-0.136] unit increase	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908
20	6761765	rs235770	T	C	rs235770	23396134	2.00E-08	NA	0.09	[0.058-0.12] unit decrease	37,382 European ancestry individuals; 578 Han Chinese ancestry individuals; 3,417 Chinese Singaporean ancestry individuals; 2,273 Singaporean Malaysian ancestry individuals; 2,108 Singaporean Indian ancestry individuals	Singaporean Malaysian(2273)	Han Chinese(578)	Singaporean Indian(2108)	European(37382)	Chinese Singaporean(3417)	ALL(45758)	ASN(6268)	EUR(37382)	SAN(2108)	ALL(45758)	Refractive error	HPOID:0000478	Abnormality of the eye	DOID:9835	refractive error	D012030	Refractive Errors	EFOID:0003908

Mapped by lexical matching(Total Items:0)
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Mapped by homologous gene(Total Items:0)
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Chemical(Total Drugs:0)
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FDA approved drug and dosage information(Total Drugs:0)
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FDA labeling changes(Total Drugs:0)
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