PedAM
Pediatric Disease Annotations & Medicines
| recurrent respiratory papillomatosis | ||||
| Disease ID | 1702 |
|---|---|
| Disease | recurrent respiratory papillomatosis |
| Definition | A rare disease caused by the human papillomavirus (HPV), most commonly types 6 and 11, that affects tissue along the respiratory tract with the majority of cases affecting the larynx. The disease has a bimodal distribution and manifests in those younger than age 5, juvenile-onset recurrent respiratory papillomatosis (JORRP), and those older than age 40, adult-onset recurrent respiratory papillomatosis (AORRP). JORRP is more common and more severe in presentation than AORRP. In a small percentage of patients, respiratory papillomas may undergo malignant transformation to squamous cell carcinomas that have a poor prognosis. |
| Synonym | juvenile laryngeal papilloma juvenile-onset recurrent respiratory papillomatosis laryngeal papilloma, recurrent recurrent respiratory papillomatosis (disorder) respiratory papillomatosis |
| Orphanet | |
| UMLS | C1168198 |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:5) C0007137 | squamous cell carcinoma | 2 C0004096 | asthma | 1 C0242379 | lung cancer | 1 C0030354 | papilloma | 1 C0042769 | virus infection | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | Entrez_id | Symbol | Resource(Total Genes:22) 3119 | HLA-DQB1 | infer 3123 | HLA-DRB1 | infer 6890 | TAP1 | infer 3105 | HLA-A | infer 3106 | HLA-B | infer 3107 | HLA-C | infer 3802 | KIR2DL1 | infer 3803 | KIR2DL2 | infer 3804 | KIR2DL3 | infer 3805 | KIR2DL4 | infer 57292 | KIR2DL5A | infer 554300 | KIR2DP1 | infer 3806 | KIR2DS1 | infer 100132285 | KIR2DS2 | infer 3808 | KIR2DS3 | infer 3809 | KIR2DS4 | infer 3810 | KIR2DS5 | infer 3811 | KIR3DL1 | infer 3812 | KIR3DL2 | infer 115653 | KIR3DL3 | infer 548594 | KIR3DP1 | infer 3813 | KIR3DS1 | infer |
| Text Mined Gene | (Waiting for update.) |
| Locus | (Waiting for update.) |
| Disease ID | 1702 |
|---|---|
| Disease | recurrent respiratory papillomatosis |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:5) HP:0030731 | Carcinoma | 2 HP:0002860 | Squamous cell carcinoma | 2 HP:0002099 | Asthma | 1 HP:0200043 | Verrucae | 1 HP:0012740 | Papilloma | 1 |
| Disease ID | 1702 |
|---|---|
| Disease | recurrent respiratory papillomatosis |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
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All Snps(Total Genotypes:0) | |
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GWASdb Annotation(Total Genotypes:0) | |
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GWASdb Snp Trait(Total Genotypes:0) | |
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Mapped by lexical matching(Total Items:0) |
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Mapped by homologous gene(Total Items:0) |
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Chemical(Total Drugs:0) | |
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FDA approved drug and dosage information(Total Drugs:0) | |
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FDA labeling changes(Total Drugs:0) | |
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