PedAM
Pediatric Disease Annotations & Medicines
| reactive arthritis | ||||
| Disease ID | 151 |
|---|---|
| Disease | reactive arthritis |
| Integrated Phenotype | HPO | Name(Total Integrated Phenotypes:26) HP:0002037 | Inflammation of the large intestine HP:0002829 | Arthralgia HP:0001824 | Weight loss HP:0100773 | Cartilage destruction HP:0002103 | Abnormality of the pleura HP:0002014 | Diarrhea HP:0001945 | Fever HP:0200039 | Pustule HP:0008391 | Dystrophic fingernails HP:0001386 | Joint swelling HP:0002206 | Pulmonary fibrosis HP:0100543 | Cognitive impairment HP:0002093 | Respiratory insufficiency HP:0001659 | Aortic regurgitation HP:0000962 | Hyperkeratosis HP:0011107 | Recurrent aphthous stomatitis HP:0100686 | Enthesitis HP:0000010 | Recurrent urinary tract infections HP:0001597 | Abnormality of the nail HP:0000509 | Conjunctivitis HP:0001369 | Arthritis HP:0001701 | Pericarditis HP:0001387 | Joint stiffness HP:0000613 | Photophobia HP:0002027 | Abdominal pain HP:0002754 | Osteomyelitis |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:11) HP:0001369 | Arthritis | 3 HP:0003765 | Psoriasis | 2 HP:0001370 | Rheumatoid arthritis | 2 HP:0000622 | Blurred vision | 1 HP:0000509 | Conjunctivitis | 1 HP:0000491 | Corneal inflammation | 1 HP:0000554 | Uveitis | 1 HP:0003040 | Arthropathy | 1 HP:0001659 | Aortic insufficiency | 1 HP:0001945 | Fever | 1 HP:0000010 | Frequent urinary tract infections | 1 |
| Disease ID | 151 |
|---|---|
| Disease | reactive arthritis |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:17) C2707258 | infections C2364133 | infection C1963079 | restrictive cardiomyopathy C0519935 | chlamydia trachomatis C0518948 | chlamydia trachomatis infection C0403762 | circinate balanitis C0343386 | clostridium difficile infection C0302359 | shigella flexneri C0043407 | yersinia infections C0043407 | yersinia infection C0039103 | synovitis C0017661 | iga nephropathy C0008149 | chlamydial infection C0008149 | chlamydia infection C0008149 | chlamydia C0004623 | bacterial infections C0003864 | joint inflammation |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:6) C0008148 | chlamydia | 5 C0008151 | chlamydia trachomatis | 4 C0009450 | infection | 3 C0021311 | infections | 3 C0518948 | chlamydia trachomatis infection | 1 C0004623 | bacterial infections | 1 |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
All Snps(Total Genotypes:2) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs4986790 | 16567359 | 7099 | TLR4 | umls:C0085435 | BeFree | Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms do not contribute to disease susceptibility in either AS or ReA. | 0.00554839 | 2006 | TLR4 | 9 | 117713024 | A | G |
| rs4986791 | 16567359 | 7099 | TLR4 | umls:C0085435 | BeFree | Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms do not contribute to disease susceptibility in either AS or ReA. | 0.00554839 | 2006 | TLR4 | 9 | 117713324 | C | T |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
|---|
| (Waiting for update.) |
Mapped by homologous gene(Total Items:1) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0001723 | Restrictive cardiomyopathy | MP:0004345 | abnormal acromion morphology;HP:0100769 | Synovitis |
Chemical(Total Drugs:1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0085435 | methotrexate | D008727 | 1959/5/2 | arthritis, reactive | MESH:D016918 | therapeutic | 5150075 | ||
FDA approved drug and dosage information(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |