PedAM
Pediatric Disease Annotations & Medicines
| q fever | ||||
| Disease ID | 263 |
|---|---|
| Disease | q fever |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:26) HP:0012115 | Liver inflammation | 9 HP:0002090 | Pneumonia | 6 HP:0002617 | Aneurysmal dilatation | 5 HP:0100584 | Endocarditis | 4 HP:0100653 | Optic neuritis | 3 HP:0200119 | Acute liver inflammation | 3 HP:0001744 | Splenomegaly | 2 HP:0012378 | Fatigue | 2 HP:0004942 | Aortic aneurysm | 2 HP:0000099 | Glomerular nephritis | 1 HP:0011134 | Mild fever | 1 HP:0002665 | Lymphoma | 1 HP:0100806 | Sepsis | 1 HP:0001297 | Cerebral vascular events | 1 HP:0000083 | Renal insufficiency | 1 HP:0100523 | Hepatic abscess | 1 HP:0005268 | Spontaneous abortion | 1 HP:0003613 | Antiphospholipid antibodies | 1 HP:0012735 | Coughing | 1 HP:0001945 | Fever | 1 HP:0012387 | Bronchitis | 1 HP:0012432 | Chronic fatigue | 1 HP:0002621 | Atherosclerosis | 1 HP:0001919 | Acute renal failure | 1 HP:0001890 | Autoimmune hemolytic anemia | 1 HP:0001082 | Cholecystitis | 1 |
| Disease ID | 263 |
|---|---|
| Disease | q fever |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:37) C2707258 | infections C1963266 | uveitis C1963211 | pericarditis C1963078 | brachial plexopathy C1962971 | myocarditis C1439298 | circulating anticoagulants C1393529 | vascular complications C0919823 | cytolytic hepatitis C0876991 | hemophagocytosis C0857305 | thrombocytopenic purpura C0752303 | urological manifestations C0393799 | miller fisher syndrome C0267842 | acute acalculous cholecystitis C0267797 | acute hepatitis C0264383 | organizing pneumonia C0263678 | acute arthritis C0235369 | granulomatous hepatitis C0178416 | hypoplastic anemia C0149520 | acute cholecystitis C0085605 | hepatic failure C0035243 | respiratory tract infections C0035222 | adult respiratory distress syndrome C0034362 | derrick-burnet disease C0034065 | pulmonary embolism C0033975 | psychosis C0032285 | pneumonias C0032285 | pneumonia C0023501 | leukemoid reaction C0023241 | legionnaires' disease C0019693 | human immunodeficiency virus C0019158 | hepatitis C0014122 | infectious endocarditis C0014121 | bacterial endocarditis C0014118 | endocarditis C0001360 | acute thyroiditis C0000786 | spontaneous abortions C0000786 | spontaneous abortion |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:7) C0019158 | hepatitis | 9 C0032285 | pneumonia | 6 C0014118 | endocarditis | 4 C0021311 | infections | 4 C0267797 | acute hepatitis | 3 C0235369 | granulomatous hepatitis | 2 C0000786 | spontaneous abortion | 1 |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
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| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
Chemical(Total Drugs:2) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0034362 | imipramine | D007099 | 50-49-7 | q fever | MESH:D011778 | therapeutic | 16469060 | ||
| C0034362 | lovastatin | D008148 | 75330-75-5 | q fever | MESH:D011778 | therapeutic | 16469060 | ||
FDA approved drug and dosage information(Total Drugs:1) | ||||||||
|---|---|---|---|---|---|---|---|---|
| DiseaseID | Drug_name | active_ingredients | strength | Dosage Form/Route | Marketing Status | TE code | RLD | RS |
| MESH:D011778 | mevacor | lovastatin | 10MG Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons | TABLET;ORAL | Discontinued | None | Yes | No |
FDA labeling changes(Total Drugs:1) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DiseaseID | Pediatric_Labeling_Date | Trade_Name | Generic_Name_or_Proper_Name | Indications Studied | Label Changes Summary | Product Labeling | BPCA(B) | PREA(P) | BPCA(B) and PREA(P) | Pediatric Rule (R) | Sponsor | Pediatric Exclusivity Granted Date | NNPS |
| MESH:D011778 | 02/14/2002 | mevacor | lovastatin | Heterozygous Familial Hypercholesterolemia | New indication in adolescent boys and girls (at least one year post-menarche) 10-17 years of age | Labeling | B | - | - | - | Merck | 07/17/2001 | FALSE' |