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PedAM

Pediatric Disease Annotations & Medicines



   pulmonary tuberculosis
  

Disease ID 849
Disease pulmonary tuberculosis
Definition
MYCOBACTERIUM infections of the lung.
Synonym
consumption, pulmonary
consumptions, pulmonary
lung tb
lung tuberculosis
phthises, pulmonary
phthisis
phthisis, pulmonary
ptb - pulmonary tuberculosis
pulm tuberculoses
pulm tuberculosis
pulmonary consumption
pulmonary consumptions
pulmonary phthises
pulmonary phthisis
pulmonary tb
pulmonary tb nos-unspec
pulmonary tuberculoses
pulmonary tuberculosis (disorder)
pulmonary tuberculosis nos
pulmonary tuberculosis nos (disorder)
pulmonary tuberculosis, unspecified, unspecified
respiratory tuberculosis
respiratory tuberculosis (disorder)
respiratory tuberculosis nos
rtb - respiratory tuberculosis
tb - pulmonary tuberculosis
tuberculoses pulm
tuberculoses, pulmonary
tuberculosis of lung nos
tuberculosis of respiratory system
tuberculosis of respiratory system (disorder)
tuberculosis pulm
tuberculosis resp (excl a70)
tuberculosis respiratory
tuberculosis respiratory (excluding a70)
tuberculosis, pulmonary
tuberculosis, pulmonary [disease/finding]
unspecified pulmonary tuberculosis
DOID
UMLS
C0041327
MeSH
SNOMED-CT
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:150)
C0041296  |  tuberculosis  |  42
C0011847  |  diabetes  |  16
C0011849  |  diabetes mellitus  |  12
C0011860  |  type 2 diabetes  |  7
C0024115  |  pulmonary disease  |  6
C0242379  |  lung cancer  |  4
C0037116  |  silicosis  |  4
C0024299  |  lymphoma  |  4
C0011860  |  type 2 diabetes mellitus  |  4
C0020538  |  hypertension  |  3
C0032273  |  pneumoconiosis  |  3
C0040034  |  thrombocytopenia  |  3
C0032231  |  pleurisy  |  3
C0275911  |  intestinal tuberculosis  |  3
C0041326  |  tuberculous pleurisy  |  3
C0035222  |  acute respiratory distress syndrome  |  3
C1704437  |  respiratory distress syndrome  |  3
C0041332  |  urinary tuberculosis  |  2
C0041333  |  genitourinary tuberculosis  |  2
C0032326  |  pneumothorax  |  2
C0032285  |  pneumonia  |  2
C0024115  |  lung disease  |  2
C0024115  |  pulmonary diseases  |  2
C0041309  |  cutaneous tuberculosis  |  2
C0041315  |  laryngeal tuberculosis  |  2
C0011570  |  depression  |  2
C0019158  |  hepatitis  |  2
C0002874  |  aplastic anemia  |  2
C0003873  |  rheumatoid arthritis  |  2
C0023418  |  leukemia  |  2
C0036202  |  sarcoidosis  |  2
C0162429  |  malnutrition  |  2
C0018021  |  goitre  |  2
C1145670  |  respiratory failure  |  2
C0600260  |  obstructive pulmonary disease  |  2
C0024117  |  chronic obstructive pulmonary disease  |  2
C0003864  |  arthritis  |  2
C0041326  |  pleural tuberculosis  |  2
C0272286  |  immune thrombocytopenia  |  2
C0011334  |  cavities  |  2
C0034065  |  pulmonary embolism  |  2
C0019163  |  hepatitis b  |  1
C0039103  |  synovitis  |  1
C0042870  |  vitamin d deficiency  |  1
C0032319  |  pneumopericardium  |  1
C0020626  |  hypoparathyroidism  |  1
C0031542  |  phlebitis  |  1
C0018799  |  heart disease  |  1
C0162429  |  malnourished  |  1
C0002895  |  sickle cell anaemia  |  1
C0684249  |  carcinoma of the lung  |  1
C0001973  |  alcoholism  |  1
C0035204  |  respiratory disease  |  1
C0035078  |  renal failure  |  1
C0025303  |  meningococcal disease  |  1
C0023470  |  myeloid leukemia  |  1
C0600260  |  obstructive airway disease  |  1
C0033860  |  psoriasis  |  1
C0041341  |  tuberous sclerosis  |  1
C0026654  |  moyamoya  |  1
C0276688  |  pulmonary cryptococcosis  |  1
C0034050  |  alveolar proteinosis  |  1
C0030421  |  paraganglioma  |  1
C0026946  |  fungal infection  |  1
C0162429  |  undernutrition  |  1
C0029443  |  osteomyelitis  |  1
C0018023  |  nodular goitre  |  1
C0027873  |  neuromyelitis optica  |  1
C0003165  |  anthracosis  |  1
C0403529  |  goodpasture's syndrome  |  1
C0020542  |  pulmonary hypertension  |  1
C0021400  |  influenza  |  1
C0034072  |  pulmonary heart disease  |  1
C0031154  |  peritonitis  |  1
C0042769  |  viral infection  |  1
C0020538  |  systemic hypertension  |  1
C0025229  |  melioidosis  |  1
C0004030  |  aspergillosis  |  1
C0008698  |  maxillary sinusitis  |  1
C0018378  |  guillain-barre syndrome  |  1
C0011603  |  dermatitis  |  1
C0023343  |  leprosy  |  1
C0028242  |  nocardiosis  |  1
C0018799  |  cardiac disease  |  1
C0002871  |  anemia  |  1
C0010674  |  cystic fibrosis  |  1
C0018801  |  heart failure  |  1
C0079744  |  diffuse large b-cell lymphoma  |  1
C0002871  |  anaemia  |  1
C0238074  |  chronic pulmonary heart disease  |  1
C0206526  |  multidrug-resistant tuberculosis  |  1
C0024299  |  lymphomas  |  1
C0018799  |  cardiac diseases  |  1
C0037928  |  myelopathy  |  1
C0031046  |  pericarditis  |  1
C0037199  |  sinusitis  |  1
C0041328  |  renal tuberculosis  |  1
C0162429  |  nutritional deficiency  |  1
C0029882  |  otitis media  |  1
C0342208  |  multinodular goitre  |  1
C0010414  |  cryptococcosis  |  1
C0035204  |  respiratory diseases  |  1
C0022661  |  chronic renal failure  |  1
C0023467  |  acute myelocytic leukemia  |  1
C0238301  |  nasopharyngeal carcinoma  |  1
C0024117  |  chronic obstructive airway disease  |  1
C0004943  |  behcet's disease  |  1
C0023470  |  myelocytic leukemia  |  1
C0242342  |  sheehan syndrome  |  1
C0004623  |  bacterial disease  |  1
C0041313  |  hepatic tuberculosis  |  1
C0043117  |  immune thrombocytopenic purpura  |  1
C0006625  |  cachexia  |  1
C0034069  |  pulmonary fibrosis  |  1
C0042769  |  virus infection  |  1
C0519030  |  klebsiella pneumonia  |  1
C0013990  |  emphysema  |  1
C0024312  |  lymphopenia  |  1
C0041327  |  pulmonary tb  |  1
C0027813  |  neuritis  |  1
C0032305  |  pneumocystis pneumonia  |  1
C0034050  |  pulmonary alveolar proteinosis  |  1
C0001418  |  adenocarcinoma  |  1
C0497327  |  dementia  |  1
C0035078  |  kidney failure  |  1
C0042870  |  vitamin d defic  |  1
C0029134  |  optic neuritis  |  1
C0021141  |  syndrome of inappropriate antidiuretic hormone secretion  |  1
C0155862  |  pneumococcal pneumonia  |  1
C0024141  |  systemic lupus erythematosus  |  1
C0152013  |  adenocarcinoma of the lung  |  1
C0751674  |  lymphangioleiomyomatosis  |  1
C0034150  |  purpura  |  1
C0519063  |  pulmonary lymphoma  |  1
C0019196  |  hepatitis c  |  1
C0038828  |  superior mesenteric artery syndrome  |  1
C0024131  |  lupus vulgaris  |  1
C0023281  |  leishmaniasis  |  1
C0036202  |  sarcoid  |  1
C0032305  |  pneumocystis  |  1
C0079731  |  b-cell lymphoma  |  1
C0023467  |  acute myeloid leukemia  |  1
C0023890  |  cirrhosis  |  1
C0026654  |  moyamoya syndrome  |  1
C0043117  |  idiopathic thrombocytopenic purpura  |  1
C0007177  |  cardiac tamponade  |  1
C0026848  |  myopathy  |  1
C0029456  |  osteoporosis  |  1
C0018099  |  gout  |  1
C0007121  |  bronchogenic carcinoma  |  1
Curated Gene
Entrez_id | Symbol | Resource(Total Genes:3)
CCL2  |  6347  |  CTD_human
CD209  |  30835  |  CTD_human
ASAP1  |  50807  |  CTD_human
Inferring Gene
Entrez_id | Symbol | Resource(Total Genes:56)
3123  |  HLA-DRB1  |  infer
3459  |  IFNGR1  |  infer
7421  |  VDR  |  infer
5243  |  ABCB1  |  infer
1636  |  ACE  |  infer
185  |  AGTR1  |  infer
186  |  AGTR2  |  infer
207  |  AKT1  |  infer
240  |  ALOX5  |  infer
6347  |  CCL2  |  infer
6352  |  CCL5  |  infer
929  |  CD14  |  infer
30835  |  CD209  |  infer
1522  |  CTSZ  |  infer
1543  |  CYP1A1  |  infer
1594  |  CYP27B1  |  infer
1557  |  CYP2C19  |  infer
1559  |  CYP2C9  |  infer
1565  |  CYP2D6  |  infer
1769  |  DNAH8  |  infer
2212  |  FCGR2A  |  infer
2214  |  FCGR3A  |  infer
2944  |  GSTM1  |  infer
2952  |  GSTT1  |  infer
3105  |  HLA-A  |  infer
3106  |  HLA-B  |  infer
3119  |  HLA-DQB1  |  infer
3458  |  IFNG  |  infer
3586  |  IL10  |  infer
3592  |  IL12A  |  infer
3593  |  IL12B  |  infer
3606  |  IL18  |  infer
3553  |  IL1B  |  infer
3557  |  IL1RN  |  infer
3558  |  IL2  |  infer
3565  |  IL4  |  infer
3569  |  IL6  |  infer
3659  |  IRF1  |  infer
345611  |  IRGM  |  infer
4049  |  LTA  |  infer
4153  |  MBL2  |  infer
4159  |  MC3R  |  infer
4170  |  MCL1  |  infer
4282  |  MIF  |  infer
4312  |  MMP1  |  infer
4318  |  MMP9  |  infer
10  |  NAT2  |  infer
64127  |  NOD2  |  infer
5027  |  P2RX7  |  infer
26191  |  PTPN22  |  infer
6556  |  SLC11A1  |  infer
7040  |  TGFB1  |  infer
7097  |  TLR2  |  infer
7099  |  TLR4  |  infer
51311  |  TLR8  |  infer
7124  |  TNF  |  infer
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:305)
6376  |  CX3CL1  |  DISEASES
7132  |  TNFRSF1A  |  DISEASES
30009  |  TBX21  |  DISEASES
4282  |  MIF  |  DISEASES
3002  |  GZMB  |  DISEASES
55734  |  ZFP64  |  DISEASES
1522  |  CTSZ  |  DISEASES
51311  |  TLR8  |  DISEASES
973  |  CD79A  |  DISEASES
3036  |  HAS1  |  DISEASES
5444  |  PON1  |  DISEASES
6348  |  CCL3  |  DISEASES
4353  |  MPO  |  DISEASES
6347  |  CCL2  |  DISEASES
6346  |  CCL1  |  DISEASES
29098  |  RANGRF  |  DISEASES
952  |  CD38  |  DISEASES
3558  |  IL2  |  DISEASES
969  |  CD69  |  DISEASES
3458  |  IFNG  |  DISEASES
2026  |  ENO2  |  DISEASES
3820  |  KLRB1  |  DISEASES
168090  |  C6orf118  |  DISEASES
6908  |  TBP  |  DISEASES
5961  |  PRPH2  |  DISEASES
3565  |  IL4  |  DISEASES
3567  |  IL5  |  DISEASES
9168  |  TMSB10  |  DISEASES
6556  |  SLC11A1  |  DISEASES
3554  |  IL1R1  |  DISEASES
7475  |  WNT6  |  DISEASES
5657  |  PRTN3  |  DISEASES
8574  |  AKR7A2  |  DISEASES
6402  |  SELL  |  DISEASES
4317  |  MMP8  |  DISEASES
4360  |  MRC1  |  DISEASES
7374  |  UNG  |  DISEASES
28981  |  IFT81  |  DISEASES
725  |  C4BPB  |  DISEASES
3623  |  INHA  |  DISEASES
4159  |  MC3R  |  DISEASES
6431  |  SRSF6  |  DISEASES
54210  |  TREM1  |  DISEASES
2069  |  EREG  |  DISEASES
55831  |  EMC3  |  DISEASES
3659  |  IRF1  |  DISEASES
10870  |  HCST  |  DISEASES
1236  |  CCR7  |  DISEASES
5199  |  CFP  |  DISEASES
6351  |  CCL4  |  DISEASES
3630  |  INS  |  DISEASES
3270  |  HRC  |  DISEASES
1571  |  CYP2E1  |  DISEASES
1401  |  CRP  |  DISEASES
80263  |  TRIM45  |  DISEASES
3431  |  SP110  |  DISEASES
3569  |  IL6  |  DISEASES
6366  |  CCL21  |  DISEASES
971  |  CD72  |  DISEASES
7097  |  TLR2  |  DISEASES
4069  |  LYZ  |  DISEASES
8099  |  CDK2AP1  |  DISEASES
64285  |  RHBDF1  |  DISEASES
23071  |  ERP44  |  DISEASES
671  |  BPI  |  DISEASES
27178  |  IL37  |  DISEASES
3552  |  IL1A  |  DISEASES
3553  |  IL1B  |  DISEASES
3574  |  IL7  |  DISEASES
10578  |  GNLY  |  DISEASES
941  |  CD80  |  DISEASES
1356  |  CP  |  DISEASES
5443  |  POMC  |  DISEASES
3383  |  ICAM1  |  DISEASES
10058  |  ABCB6  |  DISEASES
26273  |  FBXO3  |  DISEASES
25996  |  REXO2  |  DISEASES
939  |  CD27  |  DISEASES
347902  |  AMIGO2  |  DISEASES
3687  |  ITGAX  |  DISEASES
8996  |  NOL3  |  DISEASES
3394  |  IRF8  |  DISEASES
25888  |  ZNF473  |  DISEASES
10899  |  JTB  |  DISEASES
52  |  ACP1  |  DISEASES
10769  |  PLK2  |  DISEASES
3001  |  GZMA  |  DISEASES
3578  |  IL9  |  DISEASES
4715  |  NDUFB9  |  DISEASES
3439  |  IFNA1  |  DISEASES
51348  |  KLRF1  |  DISEASES
3606  |  IL18  |  DISEASES
3948  |  LDHC  |  DISEASES
80224  |  NUBPL  |  DISEASES
339896  |  GADL1  |  DISEASES
129831  |  RBM45  |  DISEASES
10  |  NAT2  |  DISEASES
10563  |  CXCL13  |  DISEASES
9131  |  AIFM1  |  DISEASES
391059  |  FRRS1  |  DISEASES
776  |  CACNA1D  |  DISEASES
3460  |  IFNGR2  |  DISEASES
1636  |  ACE  |  DISEASES
5316  |  PKNOX1  |  DISEASES
2220  |  FCN2  |  DISEASES
9437  |  NCR1  |  DISEASES
643  |  CXCR5  |  DISEASES
729230  |  CCR2  |  DISEASES
1234  |  CCR5  |  DISEASES
6352  |  CCL5  |  DISEASES
6154  |  RPL26  |  DISEASES
2215  |  FCGR3B  |  DISEASES
3577  |  CXCR1  |  DISEASES
213  |  ALB  |  DISEASES
1230  |  CCR1  |  DISEASES
3600  |  IL15  |  DISEASES
9607  |  CARTPT  |  DISEASES
27242  |  TNFRSF21  |  DISEASES
1437  |  CSF2  |  DISEASES
57094  |  CPA6  |  DISEASES
120114  |  FAT3  |  DISEASES
115825  |  WDFY2  |  DISEASES
29986  |  SLC39A2  |  DISEASES
10982  |  MAPRE2  |  DISEASES
64127  |  NOD2  |  DISEASES
94235  |  GNG8  |  DISEASES
6356  |  CCL11  |  DISEASES
83657  |  DYNLRB2  |  DISEASES
1673  |  DEFB4A  |  DISEASES
11236  |  RNF139  |  DISEASES
23491  |  CES3  |  DISEASES
1051  |  CEBPB  |  DISEASES
7275  |  TUB  |  DISEASES
3627  |  CXCL10  |  DISEASES
10655  |  DMRT2  |  DISEASES
3575  |  IL7R  |  DISEASES
56246  |  MRAP  |  DISEASES
6373  |  CXCL11  |  DISEASES
83879  |  CDCA7  |  DISEASES
27087  |  B3GAT1  |  DISEASES
2147  |  F2  |  DISEASES
344561  |  GPR148  |  DISEASES
8815  |  BANF1  |  DISEASES
9024  |  BRSK2  |  DISEASES
8722  |  CTSF  |  DISEASES
1521  |  CTSW  |  DISEASES
3952  |  LEP  |  DISEASES
1909  |  EDNRA  |  DISEASES
30835  |  CD209  |  DISEASES
10859  |  LILRB1  |  DISEASES
10332  |  CLEC4M  |  DISEASES
2529  |  FUT7  |  DISEASES
4684  |  NCAM1  |  DISEASES
8685  |  MARCO  |  DISEASES
3579  |  CXCR2  |  DISEASES
2193  |  FARSA  |  DISEASES
10938  |  EHD1  |  DISEASES
4312  |  MMP1  |  DISEASES
2  |  A2M  |  DISEASES
60626  |  RIC8A  |  DISEASES
9622  |  KLK4  |  DISEASES
2318  |  FLNC  |  DISEASES
4843  |  NOS2  |  DISEASES
11187  |  PKP3  |  DISEASES
942  |  CD86  |  DISEASES
144453  |  BEST3  |  DISEASES
338440  |  ANO9  |  DISEASES
653604  |  HIST2H3D  |  DISEASES
3916  |  LAMP1  |  DISEASES
340075  |  ARSI  |  DISEASES
151888  |  BTLA  |  DISEASES
5357  |  PLS1  |  DISEASES
112744  |  IL17F  |  DISEASES
135138  |  PACRG  |  DISEASES
23583  |  SMUG1  |  DISEASES
3117  |  HLA-DQA1  |  DISEASES
6251  |  RSU1  |  DISEASES
3329  |  HSPD1  |  DISEASES
115362  |  GBP5  |  DISEASES
392636  |  AGMO  |  DISEASES
84335  |  AKT1S1  |  DISEASES
83893  |  SPATA16  |  DISEASES
3804  |  KIR2DL3  |  DISEASES
866  |  SERPINA6  |  DISEASES
3146  |  HMGB1  |  DISEASES
4077  |  NBR1  |  DISEASES
3605  |  IL17A  |  DISEASES
1465  |  CSRP1  |  DISEASES
355  |  FAS  |  DISEASES
5265  |  SERPINA1  |  DISEASES
9260  |  PDLIM7  |  DISEASES
3240  |  HP  |  DISEASES
91137  |  SLC25A46  |  DISEASES
9600  |  PITPNM1  |  DISEASES
55871  |  CBWD1  |  DISEASES
5725  |  PTBP1  |  DISEASES
26136  |  TES  |  DISEASES
6775  |  STAT4  |  DISEASES
64780  |  MICAL1  |  DISEASES
26191  |  PTPN22  |  DISEASES
3123  |  HLA-DRB1  |  DISEASES
54106  |  TLR9  |  DISEASES
9760  |  TOX  |  DISEASES
4283  |  CXCL9  |  DISEASES
7096  |  TLR1  |  DISEASES
9646  |  CTR9  |  DISEASES
54583  |  EGLN1  |  DISEASES
3142  |  HLX  |  DISEASES
462  |  SERPINC1  |  DISEASES
3459  |  IFNGR1  |  DISEASES
2214  |  FCGR3A  |  DISEASES
912  |  CD1D  |  DISEASES
922  |  CD5L  |  DISEASES
4582  |  MUC1  |  DISEASES
51175  |  TUBE1  |  DISEASES
6283  |  S100A12  |  DISEASES
7062  |  TCHH  |  DISEASES
914  |  CD2  |  DISEASES
2316  |  FLNA  |  DISEASES
959  |  CD40LG  |  DISEASES
5236  |  PGM1  |  DISEASES
4774  |  NFIA  |  DISEASES
221391  |  OPN5  |  DISEASES
9124  |  PDLIM1  |  DISEASES
64170  |  CARD9  |  DISEASES
958  |  CD40  |  DISEASES
729238  |  SFTPA2  |  DISEASES
4318  |  MMP9  |  DISEASES
80712  |  ESX1  |  DISEASES
100  |  ADA  |  DISEASES
2739  |  GLO1  |  DISEASES
5292  |  PIM1  |  DISEASES
80312  |  TET1  |  DISEASES
6429  |  SRSF4  |  DISEASES
4153  |  MBL2  |  DISEASES
7099  |  TLR4  |  DISEASES
5696  |  PSMB8  |  DISEASES
3127  |  HLA-DRB5  |  DISEASES
5089  |  PBX2  |  DISEASES
8858  |  PROZ  |  DISEASES
6392  |  SDHD  |  DISEASES
7709  |  ZBTB17  |  DISEASES
50943  |  FOXP3  |  DISEASES
3107  |  HLA-C  |  DISEASES
7133  |  TNFRSF1B  |  DISEASES
3105  |  HLA-A  |  DISEASES
1910  |  EDNRB  |  DISEASES
1114  |  CHGB  |  DISEASES
551  |  AVP  |  DISEASES
54801  |  HAUS6  |  DISEASES
1045  |  CDX2  |  DISEASES
10514  |  MYBBP1A  |  DISEASES
23464  |  GCAT  |  DISEASES
10333  |  TLR6  |  DISEASES
6710  |  SPTB  |  DISEASES
114609  |  TIRAP  |  DISEASES
29994  |  BAZ2B  |  DISEASES
11072  |  DUSP14  |  DISEASES
51520  |  LARS  |  DISEASES
51059  |  FAM135B  |  DISEASES
3029  |  HAGH  |  DISEASES
3119  |  HLA-DQB1  |  DISEASES
10410  |  IFITM3  |  DISEASES
57680  |  CHD8  |  DISEASES
245929  |  DEFB115  |  DISEASES
10747  |  MASP2  |  DISEASES
57708  |  MIER1  |  DISEASES
333932  |  HIST2H3A  |  DISEASES
7018  |  TF  |  DISEASES
9873  |  FCHSD2  |  DISEASES
7852  |  CXCR4  |  DISEASES
22891  |  ZNF365  |  DISEASES
3120  |  HLA-DQB2  |  DISEASES
2086  |  ERV3-1  |  DISEASES
26013  |  L3MBTL1  |  DISEASES
7124  |  TNF  |  DISEASES
4615  |  MYD88  |  DISEASES
3594  |  IL12RB1  |  DISEASES
4049  |  LTA  |  DISEASES
4152  |  MBD1  |  DISEASES
388372  |  CCL4L1  |  DISEASES
139728  |  PNCK  |  DISEASES
283337  |  ZNF740  |  DISEASES
3586  |  IL10  |  DISEASES
58155  |  PTBP2  |  DISEASES
133396  |  IL31RA  |  DISEASES
56244  |  BTNL2  |  DISEASES
222659  |  PXT1  |  DISEASES
846  |  CASR  |  DISEASES
5158  |  PDE6B  |  DISEASES
10189  |  ALYREF  |  DISEASES
2638  |  GC  |  DISEASES
100289462  |  DEFB4B  |  DISEASES
727897  |  MUC5B  |  DISEASES
930  |  CD19  |  DISEASES
5027  |  P2RX7  |  DISEASES
8725  |  URI1  |  DISEASES
246744  |  STH  |  DISEASES
7421  |  VDR  |  DISEASES
567  |  B2M  |  DISEASES
820  |  CAMP  |  DISEASES
246734  |  NPCDR1  |  DISEASES
55539  |  KCNQ1DN  |  DISEASES
4555  |  MT-TD  |  DISEASES
23642  |  SNHG1  |  DISEASES
Locus(Waiting for update.)
Disease ID 849
Disease pulmonary tuberculosis
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:80)
HP:0000819  |  Diabetes mellitus  |  11
HP:0002105  |  Hemoptysis  |  9
HP:0002721  |  Immunodeficiency  |  7
HP:0012735  |  Coughing  |  5
HP:0002665  |  Lymphoma  |  4
HP:0000822  |  Hypertension  |  3
HP:0002202  |  Pleural effusion  |  3
HP:0002098  |  Respiratory distress  |  3
HP:0002102  |  Pleuritis  |  3
HP:0001873  |  Low platelet count  |  3
HP:0001909  |  Leukemia  |  2
HP:0001370  |  Rheumatoid arthritis  |  2
HP:0100699  |  Scarring  |  2
HP:0004808  |  Acute myelogenous leukemia  |  2
HP:0012115  |  Liver inflammation  |  2
HP:0001903  |  Anemia  |  2
HP:0001945  |  Fever  |  2
HP:0001369  |  Arthritis  |  2
HP:0002107  |  Collapsed lung  |  2
HP:0002090  |  Pneumonia  |  2
HP:0004395  |  Malnutrition  |  2
HP:0002204  |  Pulmonary embolism  |  2
HP:0012531  |  Pain  |  2
HP:0001880  |  Eosinophilia  |  2
HP:0000853  |  Goitre  |  2
HP:0030731  |  Carcinoma  |  2
HP:0001915  |  Aplastic anemia  |  2
HP:0000716  |  Depression  |  2
HP:0001824  |  Weight loss  |  2
HP:0001973  |  Autoimmune thrombocytopenia  |  2
HP:0002835  |  Aspiration  |  1
HP:0001399  |  Liver failure  |  1
HP:0000155  |  Oral ulcer  |  1
HP:0003201  |  Rhabdomyolysis  |  1
HP:0100769  |  Synovitis  |  1
HP:0011947  |  Respiratory infection  |  1
HP:0000979  |  Purpura  |  1
HP:0003774  |  End-stage renal failure  |  1
HP:0002754  |  Bone infection  |  1
HP:0000246  |  Sinus inflammation  |  1
HP:0003113  |  Low blood chloride levels  |  1
HP:0002097  |  Pulmonary emphysema  |  1
HP:0002092  |  Pulmonary artery hypertension  |  1
HP:0100512  |  Vitamin D deficiency  |  1
HP:0002617  |  Aneurysmal dilatation  |  1
HP:0002664  |  Neoplasia  |  1
HP:0002716  |  Lymph node hyperplasia  |  1
HP:0200123  |  Chronic liver inflammation  |  1
HP:0006510  |  Chronic obstructive pulmonary disease  |  1
HP:0001907  |  Thromboembolic disease  |  1
HP:0012191  |  B-cell lymphoma  |  1
HP:0001394  |  Hepatic cirrhosis  |  1
HP:0100653  |  Optic neuritis  |  1
HP:0002527  |  Falls  |  1
HP:0002586  |  Peritonitis  |  1
HP:0030150  |  Plasmacytosis  |  1
HP:0006532  |  Pneumonia, recurrent episodes  |  1
HP:0006517  |  Alveolar proteinosis  |  1
HP:0002089  |  Hypoplastic lungs  |  1
HP:0004326  |  Cachexia  |  1
HP:0002902  |  Hyponatremia  |  1
HP:0000388  |  Otitis media  |  1
HP:0003198  |  Myopathic changes  |  1
HP:0002725  |  Systemic lupus erythematosus  |  1
HP:0012324  |  Myeloid leukemia  |  1
HP:0002878  |  Respiratory failure  |  1
HP:0000829  |  Hypoparathyroidism  |  1
HP:0004713  |  Reversible renal failure  |  1
HP:0003765  |  Psoriasis  |  1
HP:0000939  |  Osteoporosis  |  1
HP:0000083  |  Renal insufficiency  |  1
HP:0011771  |  Autoimmune hypoparathyroidism  |  1
HP:0000726  |  Dementia  |  1
HP:0001635  |  Congestive heart failure  |  1
HP:0100749  |  Thoracic pain  |  1
HP:0001888  |  Lymphocytopenia  |  1
HP:0002668  |  Paragangliomas  |  1
HP:0002206  |  Pulmonary fibrosis  |  1
HP:0002196  |  Myelopathy  |  1
HP:0011953  |  Pulmonary lymphoma  |  1
Disease ID 849
Disease pulmonary tuberculosis
Manually Symptom(Waiting for update.)
Text Mined Symptom
UMLS | Name | Sentences' Count(Total Symptoms:63)
C0009450  |  infection  |  19
C0011847  |  diabetes  |  15
C0011849  |  diabetes mellitus  |  11
C0019079  |  hemoptysis  |  9
C0019693  |  hiv infection  |  9
C0021051  |  immunodeficiency  |  6
C0010200  |  cough  |  4
C0037116  |  silicosis  |  4
C0242379  |  lung cancer  |  4
C0040034  |  thrombocytopenia  |  3
C0021311  |  infections  |  3
C0019079  |  haemoptysis  |  3
C0020538  |  hypertension  |  3
C0032231  |  pleurisy  |  3
C0032227  |  pleural effusion  |  3
C0748159  |  pulmonary involvement  |  3
C0011570  |  depression  |  2
C0015967  |  fever  |  2
C0272286  |  immune thrombocytopenia  |  2
C0011334  |  cavities  |  2
C0030193  |  pain  |  2
C0041315  |  laryngeal tuberculosis  |  2
C0032326  |  pneumothorax  |  2
C0019693  |  human immunodeficiency virus infection  |  2
C0264395  |  swyer-james syndrome  |  2
C0014457  |  eosinophilia  |  2
C0024115  |  lung disease  |  2
C0032285  |  pneumonia  |  2
C0276651  |  aspergilloma  |  2
C0162429  |  malnutrition  |  2
C0019158  |  hepatitis  |  2
C0002871  |  anemia  |  1
C0042870  |  vitamin d deficiency  |  1
C0043117  |  immune thrombocytopenic purpura  |  1
C1145670  |  respiratory failure  |  1
C0041295  |  tuberculoma  |  1
C0034050  |  pulmonary alveolar proteinosis  |  1
C0032320  |  pneumoperitoneum  |  1
C0024131  |  lupus vulgaris  |  1
C0004030  |  aspergillosis  |  1
C0041328  |  renal tuberculosis  |  1
C0001973  |  alcoholism  |  1
C0007121  |  bronchogenic carcinoma  |  1
C0850497  |  immune deficiency  |  1
C0019163  |  hepatitis b  |  1
C0010200  |  coughing  |  1
C0021400  |  influenza  |  1
C0008031  |  chest pain  |  1
C0013990  |  emphysema  |  1
C0684249  |  carcinoma of the lung  |  1
C0264490  |  acute respiratory failure  |  1
C0041312  |  gastrointestinal tuberculosis  |  1
C0024228  |  lymphadenopathy  |  1
C0178703  |  hypertrophic osteoarthropathy  |  1
C0040038  |  thromboembolism  |  1
C0032749  |  post-kala-azar dermal leishmaniasis  |  1
C0020625  |  hyponatremia  |  1
C0002871  |  anaemia  |  1
C0235378  |  hepatotoxicity  |  1
C0559523  |  genital tuberculosis  |  1
C0034150  |  purpura  |  1
C0001883  |  airway obstruction  |  1
C0010414  |  cryptococcosis  |  1
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:103)
snpId pubmedId geneId geneSymbol diseaseId sourceId sentence score Year geneSymbol_dbSNP CHROMOSOME POS REF ALT
rs1041981227716103565IL4umls:C0041327BeFreeUsing multiple corrections, significant overall risk against PTB was observed at seven loci which included variants in IFNG at rs1861493 and rs1861494; IL1RA at rs4252019, IL4 variant rs2070874, IL12 variants rs3212220, rs2853694 and TNFB variant rs1041981.0.0069914752012LTA;LOC100287329631573007CA
rs121917864238300557097TLR2umls:C0041327BeFreeOur data suggest that 597T/C polymorphism, but not Arg677Trp polymorphism, of the TLR-2 gene is a risk factor for susceptibility to PTB in a sample of Iranian population.0.0145495792012TLR24153704936CT
rs138968705207979057097TLR2umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0145495792010TLR6438828278GA
rs1389687052079790510333TLR6umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0002714422010TLR6438828278GA
rs138968705207979057099TLR4umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0116396632010TLR6438828278GA
rs1389687052079790554106TLR9umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0016286512010TLR6438828278GA
rs138968705207979057096TLR1umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0010857672010TLR6438828278GA
rs172354091582502392105INTS4umls:C0041327BeFreeTo test this possibility, we examined NRAMP1 variants at the INT4 and D543N loci, as well as their association with severe forms of pulmonary tuberculosis, in 127 patients with active pulmonary tuberculosis and in 91 ethnically matched, healthy control subjects in areas of China where tuberculosis is endemic.0.0016286512005SLC11A12218395009GA,C
rs17235409217108557473WNT3umls:C0041327BeFreeThe aim of this study was to evaluate the role of three polymorphisms (D543N, TGTG deletion in 3' UTR, INT4 G/C) of NRAMP1 to susceptibility to lung tuberculosis (TB) disease.0.0016286512011SLC11A12218395009GA,C
rs17235409158250237473WNT3umls:C0041327BeFreeTo test this possibility, we examined NRAMP1 variants at the INT4 and D543N loci, as well as their association with severe forms of pulmonary tuberculosis, in 127 patients with active pulmonary tuberculosis and in 91 ethnically matched, healthy control subjects in areas of China where tuberculosis is endemic.0.0016286512005SLC11A12218395009GA,C
rs172354092171085592105INTS4umls:C0041327BeFreeThe aim of this study was to evaluate the role of three polymorphisms (D543N, TGTG deletion in 3' UTR, INT4 G/C) of NRAMP1 to susceptibility to lung tuberculosis (TB) disease.0.0016286512011SLC11A12218395009GA,C
rs179986419942750729230CCR2umls:C0041327BeFreeCCR2 V64I (G/A), monocyte chemoattractant protein-1 (MCP-1) -2518 A/G, stromal cell derived factor-1alpha; (SDF-1alpha) 3'UTR G/A and DC-SIGN gene polymorphisms were studied by polymerase chain reaction based methods in HIV-1 infected patients without TB (n=151), with pulmonary TB (PTB) (n=81) and extrapulmonary TB (n=31), 155 PTB patients without HIV and 206 healthy controls.0.0005428842009CCR2346357717GA
rs17998641994275030835CD209umls:C0041327BeFreeCCR2 V64I (G/A), monocyte chemoattractant protein-1 (MCP-1) -2518 A/G, stromal cell derived factor-1alpha; (SDF-1alpha) 3'UTR G/A and DC-SIGN gene polymorphisms were studied by polymerase chain reaction based methods in HIV-1 infected patients without TB (n=151), with pulmonary TB (PTB) (n=81) and extrapulmonary TB (n=31), 155 PTB patients without HIV and 206 healthy controls.0.1264485922009CCR2346357717GA
rs1799864199427506347CCL2umls:C0041327BeFreeCCR2 V64I (G/A), monocyte chemoattractant protein-1 (MCP-1) -2518 A/G, stromal cell derived factor-1alpha; (SDF-1alpha) 3'UTR G/A and DC-SIGN gene polymorphisms were studied by polymerase chain reaction based methods in HIV-1 infected patients without TB (n=151), with pulmonary TB (PTB) (n=81) and extrapulmonary TB (n=31), 155 PTB patients without HIV and 206 healthy controls.0.1366214252009CCR2346357717GA
rs1861493227716103565IL4umls:C0041327BeFreeUsing multiple corrections, significant overall risk against PTB was observed at seven loci which included variants in IFNG at rs1861493 and rs1861494; IL1RA at rs4252019, IL4 variant rs2070874, IL12 variants rs3212220, rs2853694 and TNFB variant rs1041981.0.0069914752012IFNG1268157416GA
rs1861494227716103565IL4umls:C0041327BeFreeUsing multiple corrections, significant overall risk against PTB was observed at seven loci which included variants in IFNG at rs1861493 and rs1861494; IL1RA at rs4252019, IL4 variant rs2070874, IL12 variants rs3212220, rs2853694 and TNFB variant rs1041981.0.0069914752012IFNG1268157629CT
rs18933522506639357591MKL1umls:C0041327BeFreeTo evaluate the possible association between Toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP; also known as MAL) rs1893352 and rs8177374 (S180L) gene polymorphisms and pulmonary tuberculosis (PTB) in a sample of Iranian population.0.0002714422014TIRAP11126290792AG
rs2070874227716103565IL4umls:C0041327BeFreeUsing multiple corrections, significant overall risk against PTB was observed at seven loci which included variants in IFNG at rs1861493 and rs1861494; IL1RA at rs4252019, IL4 variant rs2070874, IL12 variants rs3212220, rs2853694 and TNFB variant rs1041981.0.0069914752012IL45132674018CT
rs2393799216355665027P2RX7umls:C0041327BeFreeWe examined two 1513A/C and -762T/C polymorphisms at the P2X7 receptor in 168 patients with pulmonary TB (pTB), 55 patients with extrapulmonary TB (epTB) and 150 blood donors from Tunisia.0.0069055992011P2RX712121132209CT
rs24766012349977526191PTPN22umls:C0041327BeFreeThis study is the first to investigate the association between pulmonary TB and the PTPN22 1858C/T polymorphism in the Brazilian Amazon.0.0034527992013PTPN22;AP4B1-AS11113834946AG
rs24766012261427626191PTPN22umls:C0041327BeFreeSignificant differences were not observed in genotype or allele frequencies of PTPN22 C1858T in the comparison between pulmonary tuberculosis patients and healthy subjects in our Iranian population sample.0.0034527992012PTPN22;AP4B1-AS11113834946AG
rs2522137247879494440MSI1umls:C0041327BeFreeIn multivariate analysis, Musashi-1 rs2522137 was still significantly associated with lung cancer when environmental and lifestyle factors were incorporated in the model, including lower BMI; family history of cancer; prior diagnosis of chronic obstructive pulmonary disease, pneumonia, or pulmonary tuberculosis; occupational exposure to pesticide; occupational exposure to gasoline or diesel fuel; heavier smoking; and exposure to heavy cooking emissions.0.0002714422014MSI112120342128TG
rs2853694227716103565IL4umls:C0041327BeFreeUsing multiple corrections, significant overall risk against PTB was observed at seven loci which included variants in IFNG at rs1861493 and rs1861494; IL1RA at rs4252019, IL4 variant rs2070874, IL12 variants rs3212220, rs2853694 and TNFB variant rs1041981.0.0069914752012IL12B5159322080GT
rs3212220227716103565IL4umls:C0041327BeFreeUsing multiple corrections, significant overall risk against PTB was observed at seven loci which included variants in IFNG at rs1861493 and rs1861494; IL1RA at rs4252019, IL4 variant rs2070874, IL12 variants rs3212220, rs2853694 and TNFB variant rs1041981.0.0069914752012IL12B5159327187CA
rs34069356238275041522CTSZumls:C0041327BeFreeAssociation of CTSZ rs34069356 and MC3R rs6127698 gene polymorphisms with pulmonary tuberculosis.0.0026384742014CTSZ2058995705CT
rs34069356238275044159MC3Rumls:C0041327BeFreeAssociation of CTSZ rs34069356 and MC3R rs6127698 gene polymorphisms with pulmonary tuberculosis.0.0029099162014CTSZ2058995705CT
rs3707382842079790510333TLR6umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0002714422010TLR1438797857AG
rs3707382842079790554106TLR9umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0016286512010TLR1438797857AG
rs370738284207979057099TLR4umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0116396632010TLR1438797857AG
rs370738284207979057097TLR2umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0145495792010TLR1438797857AG
rs370738284207979057096TLR1umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0010857672010TLR1438797857AG
rs37648792592807751311TLR8umls:C0041327BeFreeThe frequencies of the GG genotype of SNP rs7873784 in TLR4 (OR = 2.136; 95% CI: 1.312-3.478) and the CC genotype of rs3764879 in TLR8 (OR = 1.982; 95% CI: 1.292-3.042) were also significantly higher in the PTB group than in the HC group.0.0037242412015TLR8;TLR8-AS1X12906578CG
rs3764879259280777099TLR4umls:C0041327BeFreeThe frequencies of the GG genotype of SNP rs7873784 in TLR4 (OR = 2.136; 95% CI: 1.312-3.478) and the CC genotype of rs3764879 in TLR8 (OR = 1.982; 95% CI: 1.292-3.042) were also significantly higher in the PTB group than in the HC group.0.0116396632015TLR8;TLR8-AS1X12906578CG
rs3804099238300557097TLR2umls:C0041327BeFreeOur data suggest that 597T/C polymorphism, but not Arg677Trp polymorphism, of the TLR-2 gene is a risk factor for susceptibility to PTB in a sample of Iranian population.0.0145495792012TLR24153703504TC
rs386502799207979057096TLR1umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0010857672010NANANANANA
rs3865027992079790554106TLR9umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0016286512010NANANANANA
rs3865027992079790510333TLR6umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0002714422010NANANANANA
rs386502799207979057099TLR4umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0116396632010NANANANANA
rs3865027992506639357591MKL1umls:C0041327BeFreeTo evaluate the possible association between Toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP; also known as MAL) rs1893352 and rs8177374 (S180L) gene polymorphisms and pulmonary tuberculosis (PTB) in a sample of Iranian population.0.0002714422014NANANANANA
rs386502799207979057097TLR2umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0145495792010NANANANANA
rs386547285207979057096TLR1umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0010857672010NANANANANA
rs3865472852079790510333TLR6umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0002714422010NANANANANA
rs386547285207979057099TLR4umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0116396632010NANANANANA
rs3865472852079790554106TLR9umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0016286512010NANANANANA
rs386547285207979057097TLR2umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0145495792010NANANANANA
rs4252019227716103565IL4umls:C0041327BeFreeUsing multiple corrections, significant overall risk against PTB was observed at seven loci which included variants in IFNG at rs1861493 and rs1861494; IL1RA at rs4252019, IL4 variant rs2070874, IL12 variants rs3212220, rs2853694 and TNFB variant rs1041981.0.0069914752012IL1RN2113131542CT
rs48048032375177030835CD209umls:C0041327BeFreeCD209 promoter -336 A/G (rs4804803) polymorphism is associated with susceptibility to pulmonary tuberculosis in Zahedan, southeast Iran.0.1264485922013CD209197747847AG
rs4986790207979057099TLR4umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0116396632010TLR49117713024AG
rs4986790207979057096TLR1umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0010857672010TLR49117713024AG
rs49867902079790554106TLR9umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0016286512010TLR49117713024AG
rs49867902079790510333TLR6umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0002714422010TLR49117713024AG
rs4986790155255577099TLR4umls:C0041327BeFreeThe toll-like receptor 4 Asp299Gly variant: no influence on LPS responsiveness or susceptibility to pulmonary tuberculosis in The Gambia.0.0116396632004TLR49117713024AG
rs4986790207979057097TLR2umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0145495792010TLR49117713024AG
rs4986790204031437099TLR4umls:C0041327BeFreeHuman Toll-like receptor 4 polymorphisms TLR4 Asp299Gly and Thr399Ile influence susceptibility and severity of pulmonary tuberculosis in the Asian Indian population.0.0116396632010TLR49117713024AG
rs4986790180082567099TLR4umls:C0041327BeFreeNo association between TLR4 Asp299Gly and pulmonary TB was found.0.0116396632007TLR49117713024AG
rs4986791207979057097TLR2umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0145495792010TLR49117713324CT
rs4986791207979057099TLR4umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0116396632010TLR49117713324CT
rs49867912079790510333TLR6umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0002714422010TLR49117713324CT
rs4986791204031437099TLR4umls:C0041327BeFreeHuman Toll-like receptor 4 polymorphisms TLR4 Asp299Gly and Thr399Ile influence susceptibility and severity of pulmonary tuberculosis in the Asian Indian population.0.0116396632010TLR49117713324CT
rs49867912079790554106TLR9umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0016286512010TLR49117713324CT
rs4986791207979057096TLR1umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0010857672010TLR49117713324CT
rs5743618207979057097TLR2umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0145495792010TLR1438797027CA
rs5743618206502987096TLR1umls:C0041327BeFreeThe aim of this study was to investigate whether the functional genetic variations at position 1805 G/T in TLR1, 2258 A/G in TLR2, -857 C/T, and -863 A/C in tumor necrosis factor-α (TNF-α), as well as -819 C/T in interleukin-10 (IL-10) confer susceptibility to pulmonary tuberculosis (PTB).0.0010857672010TLR1438797027CA
rs5743618235753317096TLR1umls:C0041327BeFreeHuman toll-like receptor 1 T1805G polymorphism and susceptibility to pulmonary tuberculosis in northern Spain.0.0010857672013TLR1438797027CA
rs57436182079790554106TLR9umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0016286512010TLR1438797027CA
rs5743618207979057096TLR1umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0010857672010TLR1438797027CA
rs5743618206502987097TLR2umls:C0041327BeFreeThe aim of this study was to investigate whether the functional genetic variations at position 1805 G/T in TLR1, 2258 A/G in TLR2, -857 C/T, and -863 A/C in tumor necrosis factor-α (TNF-α), as well as -819 C/T in interleukin-10 (IL-10) confer susceptibility to pulmonary tuberculosis (PTB).0.0145495792010TLR1438797027CA
rs5743618207979057099TLR4umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0116396632010TLR1438797027CA
rs57436182079790510333TLR6umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0002714422010TLR1438797027CA
rs57437082079790554106TLR9umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0016286512010TLR24153705165GA
rs5743708206502987097TLR2umls:C0041327BeFreeThe aim of this study was to investigate whether the functional genetic variations at position 1805 G/T in TLR1, 2258 A/G in TLR2, -857 C/T, and -863 A/C in tumor necrosis factor-α (TNF-α), as well as -819 C/T in interleukin-10 (IL-10) confer susceptibility to pulmonary tuberculosis (PTB).0.0145495792010TLR24153705165GA
rs5743708206502987096TLR1umls:C0041327BeFreeThe aim of this study was to investigate whether the functional genetic variations at position 1805 G/T in TLR1, 2258 A/G in TLR2, -857 C/T, and -863 A/C in tumor necrosis factor-α (TNF-α), as well as -819 C/T in interleukin-10 (IL-10) confer susceptibility to pulmonary tuberculosis (PTB).0.0010857672010TLR24153705165GA
rs5743708207979057096TLR1umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0010857672010TLR24153705165GA
rs5743708207979057097TLR2umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0145495792010TLR24153705165GA
rs5743708207979057099TLR4umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0116396632010TLR24153705165GA
rs57437082079790510333TLR6umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0002714422010TLR24153705165GA
rs5743810207979057097TLR2umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0145495792010TLR6438828729AG
rs5743810207979057099TLR4umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0116396632010TLR6438828729AG
rs57438102079790510333TLR6umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0002714422010TLR6438828729AG
rs5743810207979057096TLR1umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0010857672010TLR6438828729AG
rs57438102079790554106TLR9umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0016286512010TLR6438828729AG
rs57438362079790510333TLR6umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0002714422010TLR9352226766AG
rs57438362079790554106TLR9umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0016286512010TLR9352226766AG
rs5743836207979057096TLR1umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0010857672010TLR9352226766AG
rs5743836207979057097TLR2umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0145495792010TLR9352226766AG
rs5743836207979057099TLR4umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0116396632010TLR9352226766AG
rs6127698238275044159MC3Rumls:C0041327BeFreeAssociation of CTSZ rs34069356 and MC3R rs6127698 gene polymorphisms with pulmonary tuberculosis.0.0029099162014MC3R2056248360GT
rs6127698238275041522CTSZumls:C0041327BeFreeAssociation of CTSZ rs34069356 and MC3R rs6127698 gene polymorphisms with pulmonary tuberculosis.0.0026384742014MC3R2056248360GT
rs6853240677894615MYD88umls:C0041327BeFreeThe MyD88 rs6853 and TIRAP rs8177374 polymorphic sites are associated with resistance to human pulmonary tuberculosis.0.0002714422013MYD88338142879AG
rs685324067789114609TIRAPumls:C0041327BeFreeThe MyD88 rs6853 and TIRAP rs8177374 polymorphic sites are associated with resistance to human pulmonary tuberculosis.0.005548392013MYD88338142879AG
rs71948862221219264127NOD2umls:C0041327BeFreeIn summary, genetic polymorphisms of the SNP rs7194886 in the NOD2 gene, which were discovered in the GWAS of leprosy, might also be associated with the pulmonary tuberculosis in the Chinese population.0.0088156242012NA1650691282CT
rs7873784259280777099TLR4umls:C0041327BeFreeThe frequencies of the GG genotype of SNP rs7873784 in TLR4 (OR = 2.136; 95% CI: 1.312-3.478) and the CC genotype of rs3764879 in TLR8 (OR = 1.982; 95% CI: 1.292-3.042) were also significantly higher in the PTB group than in the HC group.0.0116396632015TLR49117716658GA,C
rs78737842592807751311TLR8umls:C0041327BeFreeThe frequencies of the GG genotype of SNP rs7873784 in TLR4 (OR = 2.136; 95% CI: 1.312-3.478) and the CC genotype of rs3764879 in TLR8 (OR = 1.982; 95% CI: 1.292-3.042) were also significantly higher in the PTB group than in the HC group.0.0037242412015TLR49117716658GA,C
rs81773742079790554106TLR9umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0016286512010TIRAP11126292948CT
rs81773742079790510333TLR6umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0002714422010TIRAP11126292948CT
rs817737424067789114609TIRAPumls:C0041327BeFreeThe MyD88 rs6853 and TIRAP rs8177374 polymorphic sites are associated with resistance to human pulmonary tuberculosis.0.005548392013TIRAP11126292948CT
rs8177374240677894615MYD88umls:C0041327BeFreeThe MyD88 rs6853 and TIRAP rs8177374 polymorphic sites are associated with resistance to human pulmonary tuberculosis.0.0002714422013TIRAP11126292948CT
rs8177374207979057096TLR1umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0010857672010TIRAP11126292948CT
rs8177374207979057099TLR4umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0116396632010TIRAP11126292948CT
rs8177374207979057097TLR2umls:C0041327BeFreeIn the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB).0.0145495792010TIRAP11126292948CT
rs81773742506639357591MKL1umls:C0041327BeFreeTo evaluate the possible association between Toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP; also known as MAL) rs1893352 and rs8177374 (S180L) gene polymorphisms and pulmonary tuberculosis (PTB) in a sample of Iranian population.0.0002714422014TIRAP11126292948CT
rs817737425066393114609TIRAPumls:C0041327BeFreeTIRAP rs8177374 gene polymorphism increased the risk of pulmonary tuberculosis in Zahedan, southeast Iran.0.005548392014TIRAP11126292948CT
rs99396092537772279068FTOumls:C0041327BeFreeThe FTO polymorphism rs9939609 is associated with a risk of pulmonary tuberculosis in the Chinese population.0.0002714422014FTO1653786615TA
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)
Mapped by lexical matching(Total Items:0)
(Waiting for update.)
Mapped by homologous gene(Total Items:0)
(Waiting for update.)
Chemical(Total Drugs:8)
CUI ChemicalName ChemicalID CasRN DiseaseName DiseaseID DirectEvidence PubMedIDs
C0041327capreomycinD00220711003-38-6tuberculosis, pulmonaryMESH:D014397therapeutic4906375
C0041327cycloserineD00352368-41-7tuberculosis, pulmonaryMESH:D014397therapeutic5271994
C0041327ethambutolD00497774-55-5tuberculosis, pulmonaryMESH:D014397therapeutic1031407
C0041327ofloxacinD01524282419-36-1tuberculosis, pulmonaryMESH:D014397therapeutic8399888
C0041327pyrazinamideD01171898-96-4tuberculosis, pulmonaryMESH:D014397therapeutic10214039
C0041327pyridoxineD011736-tuberculosis, pulmonaryMESH:D014397therapeutic4059141
C0041327rifabutinD01782872559-06-9tuberculosis, pulmonaryMESH:D014397therapeutic16321897
C0041327rifampinD01229313292-46-1tuberculosis, pulmonaryMESH:D014397therapeutic10599213
FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)
FDA labeling changes(Total Drugs:0)
(Waiting for update.)