PedAM
Pediatric Disease Annotations & Medicines
| postpartum depression | ||||
| Disease ID | 1235 |
|---|---|
| Disease | postpartum depression |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:12) HP:0000716 | Depression | 5 HP:0007302 | Bipolar disorder | 2 HP:0011856 | Pica | 1 HP:0001297 | Cerebral vascular events | 1 HP:0000821 | Underactive thyroid | 1 HP:0012075 | Personality disorder | 1 HP:0012531 | Pain | 1 HP:0100785 | Insomnia | 1 HP:0012378 | Fatigue | 1 HP:0000737 | Irritability | 1 HP:0100646 | Thyroiditis | 1 HP:0001788 | Premature rupture of membranes | 1 |
| Disease ID | 1235 |
|---|---|
| Disease | postpartum depression |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:1) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:6) | |||||||||||||
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| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs237885 | 23637833 | 5021 | OXTR | umls:C0221074 | BeFree | In contrast, the OXTR SNP rs237885 did not associate with maternal behavior, but it did associate with pre-natal (but not post-natal) depression score. | 0.000271442 | 2013 | OXTR | 3 | 8753857 | T | G |
| rs2740210 | 23941164 | 5020 | OXT | umls:C0221074 | BeFree | Genetic variation in oxytocin rs2740210 and early adversity associated with postpartum depression and breastfeeding duration. | 0.000271442 | 2013 | OXT;LOC101929098 | 20 | 3072609 | C | A |
| rs386602118 | 21997575 | 6532 | SLC6A4 | umls:C0221074 | BeFree | The present study is aimed to examine whether functional polymorphic variants, BDNF Val66Met, 5-HTTLPR, or PER2 SNP 10870, are associated with PPD symptoms and whether these genetic polymorphisms interact with season in predicting PPD symptoms. | 0.004538567 | 2011 | NA | NA | NA | NA | NA |
| rs386602118 | 21997575 | 8864 | PER2 | umls:C0221074 | BeFree | The present study is aimed to examine whether functional polymorphic variants, BDNF Val66Met, 5-HTTLPR, or PER2 SNP 10870, are associated with PPD symptoms and whether these genetic polymorphisms interact with season in predicting PPD symptoms. | 0.000542884 | 2011 | NA | NA | NA | NA | NA |
| rs4680 | 21099450 | 6532 | SLC6A4 | umls:C0221074 | BeFree | Among those with history of psychiatric problems, the COMT-Val158Met and 5HTT-LPR risk variants were associated with PPD symptoms, whereas in the absence of previous psychiatric contact only maternity stressors were related to PPD symptoms. | 0.004538567 | 2011 | COMT;MIR4761 | 22 | 19963748 | G | A |
| rs4680 | 21099450 | 1312 | COMT | umls:C0221074 | BeFree | Among those with history of psychiatric problems, the COMT-Val158Met and 5HTT-LPR risk variants were associated with PPD symptoms, whereas in the absence of previous psychiatric contact only maternity stressors were related to PPD symptoms. | 0.002638474 | 2011 | COMT;MIR4761 | 22 | 19963748 | G | A |
GWASdb Annotation(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
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| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
Chemical(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA approved drug and dosage information(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
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| (Waiting for update.) | |