PedAM

Pediatric Disease Annotations & Medicines


	posterior uveitis

Disease ID	466
Disease	posterior uveitis
Definition	Inflammation of the choroid as well as the retina and vitreous body. Some form of visual disturbance is usually present. The most important characteristics of posterior uveitis are vitreous opacities, choroiditis, and chorioretinitis.
Synonym	posterior uveitis (disorder) posterior uveitis nos posterior uveitis nos (disorder) posterior uveitis, nos uveitis posterior uveitis, posterior uveitis, posterior [disease/finding] uveitis, posterior nos
Orphanet	ORPHANET:280892
DOID	DOID:12574
UMLS	C0042167
MeSH	D015866
SNOMED-CT	SNOMEDCT_US_2016_09_01:43363007
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:24) C0042164 \| uveitis \| 5 C0042384 \| vasculitis \| 4 C0152026 \| retinal vasculitis \| 4 C0004943 \| behcet's disease \| 3 C0024441 \| macular hole \| 2 C0040561 \| ocular toxoplasmosis \| 2 C0040558 \| toxoplasmosis \| 2 C0042164 \| intraocular inflammation \| 2 C0014038 \| encephalitis \| 1 C0036202 \| sarcoidosis \| 1 C0041296 \| tuberculosis \| 1 C0086543 \| cataract \| 1 C0042769 \| virus infection \| 1 C0024441 \| macular holes \| 1 C0035326 \| retinal vascular occlusion \| 1 C0035302 \| retinal artery occlusion \| 1 C0162293 \| papillitis \| 1 C0035305 \| retinal detachments \| 1 C0030343 \| panuveitis \| 1 C0271051 \| macular edema \| 1 C0042165 \| anterior uveitis \| 1 C0006123 \| branch retinal artery occlusion \| 1 C0039128 \| syphilis \| 1 C0035305 \| retinal detachment \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:63) 1414 \| CRYBB1 \| DISEASES 10544 \| PROCR \| DISEASES 2137 \| EXTL3 \| DISEASES 973 \| CD79A \| DISEASES 5949 \| RBP3 \| DISEASES 3558 \| IL2 \| DISEASES 969 \| CD69 \| DISEASES 10804 \| GJB6 \| DISEASES 3557 \| IL1RN \| DISEASES 27348 \| TOR1B \| DISEASES 4069 \| LYZ \| DISEASES 23406 \| COTL1 \| DISEASES 898 \| CCNE1 \| DISEASES 7077 \| TIMP2 \| DISEASES 11043 \| MID2 \| DISEASES 23523 \| CABIN1 \| DISEASES 3553 \| IL1B \| DISEASES 55717 \| WDR11 \| DISEASES 832 \| CAPZB \| DISEASES 84162 \| KIAA1109 \| DISEASES 3383 \| ICAM1 \| DISEASES 306 \| ANXA3 \| DISEASES 3439 \| IFNA1 \| DISEASES 726 \| CAPN5 \| DISEASES 1636 \| ACE \| DISEASES 729230 \| CCR2 \| DISEASES 1584 \| CYP11B1 \| DISEASES 7412 \| VCAM1 \| DISEASES 2923 \| PDIA3 \| DISEASES 4909 \| NTF4 \| DISEASES 56246 \| MRAP \| DISEASES 9448 \| MAP4K4 \| DISEASES 23765 \| IL17RA \| DISEASES 5034 \| P4HB \| DISEASES 7850 \| IL1R2 \| DISEASES 3605 \| IL17A \| DISEASES 1717 \| DHCR7 \| DISEASES 3075 \| CFH \| DISEASES 959 \| CD40LG \| DISEASES 7422 \| VEGFA \| DISEASES 55315 \| SLC29A3 \| DISEASES 5464 \| PPA1 \| DISEASES 7133 \| TNFRSF1B \| DISEASES 3105 \| HLA-A \| DISEASES 4340 \| MOG \| DISEASES 10549 \| PRDX4 \| DISEASES 5272 \| SERPINB9 \| DISEASES 3122 \| HLA-DRA \| DISEASES 3676 \| ITGA4 \| DISEASES 3778 \| KCNMA1 \| DISEASES 6295 \| SAG \| DISEASES 3550 \| IK \| DISEASES 55683 \| KANSL3 \| DISEASES 7124 \| TNF \| DISEASES 3106 \| HLA-B \| DISEASES 64167 \| ERAP2 \| DISEASES 2886 \| GRB7 \| DISEASES 3586 \| IL10 \| DISEASES 629 \| CFB \| DISEASES 6171 \| RPL41 \| DISEASES 9414 \| TJP2 \| DISEASES 63895 \| PIEZO2 \| DISEASES 79104 \| MEG8 \| DISEASES
Locus	(Waiting for update.)

Disease ID	466
Disease	posterior uveitis
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:15) HP:0000554 \| Uveitis \| 5 HP:0002633 \| Vasculitis \| 4 HP:0011508 \| Macular hole \| 2 HP:0012231 \| Exudative retinal detachment \| 2 HP:0100533 \| Ocular inflammation \| 2 HP:0012121 \| Panuveitis \| 1 HP:0040049 \| Macular edema \| 1 HP:0002721 \| Immunodeficiency \| 1 HP:0000518 \| Cataract \| 1 HP:0012122 \| Anterior uveitis \| 1 HP:0000505 \| Poor vision \| 1 HP:0011531 \| Hyalitis \| 1 HP:0002383 \| Encephalitis \| 1 HP:0000541 \| Detached retina \| 1 HP:0000572 \| Visual loss \| 1

Disease ID	466
Disease	posterior uveitis
Manually Symptom	UMLS \| Name(Total Manually Symptoms:10) C2364133 \| infection C1963274 \| vasculitis C1282209 \| choroidal neovascular membrane C0730286 \| macular ischaemia C0456909 \| loss of vision C0456909 \| blindness C0340160 \| pulmonary hyalinizing granuloma C0235272 \| retinal damage C0040553 \| toxocariasis C0035326 \| retinal vascular occlusion
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:2) C0042384 \| vasculitis \| 4 C0035326 \| retinal vascular occlusion \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:1)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs1061170	23497844	3075	CFH	umls:C0042167	BeFree	Carriage of the CFH Y402H polymorphism in both alleles is associated with an increased risk for posterior uveitis and panuveitis presentation.	0.000542884	2013	CFH	1	196690107	C	T

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:1)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0042167	cyclosporine	D016572	59865-13-3	uveitis, posterior	MESH:D015866	therapeutic	11004305

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

Web
Analytics