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PedAM

Pediatric Disease Annotations & Medicines



   post-traumatic stress disorder
  

Disease ID 656
Disease post-traumatic stress disorder
Definition
A class of traumatic stress disorders with symptoms that last more than one month.
Synonym
#NAME?
combat fatigue
disorder, post-traumatic stress
neuroses, post traumatic
neuroses, post-traumatic
neuroses, posttraumatic
post traumatic stress dis
post traumatic stress disorder
post traumatic stress disorders
post traumatic stress syndrome
post-traumatic neuroses
post-traumatic stress disorder (disorder)
post-traumatic stress disorder (ptsd)
post-traumatic stress disorders
post-traumatic stress syndrome
posttraumatic neuroses
posttraumatic stress dis
posttraumatic stress disorder
posttraumatic stress disorder (disorder)
posttraumatic stress disorder nos
posttraumatic stress disorder, nos
posttraumatic stress disorders
ptsd
ptsd - post-traumatic stress disorder
stress dis post traumatic
stress dis posttraumatic
stress disorder, post traumatic
stress disorder, post-traumatic
stress disorder, posttraumatic
stress disorders, post traumatic
stress disorders, post-traumatic
stress disorders, post-traumatic [disease/finding]
stress disorders, posttraumatic
traumatic neuroses
traumatic neurosis
DOID
UMLS
C0038436
MeSH
SNOMED-CT
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:61)
C0011570  |  depression  |  14
C0003467  |  anxiety  |  8
C0036341  |  schizophrenia  |  6
C0037317  |  sleep disturbance  |  6
C0003469  |  anxiety disorder  |  5
C0007222  |  cardiovascular disease  |  5
C0042373  |  vascular disease  |  5
C0003469  |  anxiety disorders  |  4
C0037317  |  sleep disturbances  |  4
C0033975  |  psychotic disorder  |  3
C0003125  |  anorexia nervosa  |  2
C0006142  |  breast cancer  |  2
C0376358  |  prostate cancer  |  2
C0021359  |  infertility  |  2
C0948265  |  metabolic syndrome  |  2
C0041696  |  major depression  |  2
C0027051  |  myocardial infarct  |  2
C0027051  |  myocardial infarction  |  2
C0016053  |  fibromyalgia syndrome  |  2
C0013473  |  eating disorder  |  2
C0031212  |  personality disorders  |  2
C0016053  |  fibromyalgia  |  2
C0041696  |  major depressive disorder  |  2
C0149931  |  migraine  |  2
C0004936  |  mental disorders  |  2
C0024115  |  pulmonary disease  |  1
C0011847  |  diabetes  |  1
C0524851  |  neurodegenerative diseases  |  1
C0040188  |  tic disorders  |  1
C1140680  |  ovarian cancer  |  1
C0025303  |  meningococcal disease  |  1
C0012236  |  22q11.2 deletion syndrome  |  1
C0033975  |  psychotic disorders  |  1
C0022104  |  irritable bowel  |  1
C0002395  |  dementia of the alzheimer's type  |  1
C0014544  |  epilepsy  |  1
C0004096  |  asthma  |  1
C0030319  |  panic disorder  |  1
C0033953  |  sexual dysfunction  |  1
C0221074  |  postpartum depression  |  1
C0014556  |  temporal lobe epilepsy  |  1
C1140680  |  ovarian ca  |  1
C0037315  |  sleep-disordered breathing  |  1
C0032914  |  preeclampsia  |  1
C0001818  |  agoraphobia  |  1
C0524851  |  neurodegenerative disease  |  1
C0022104  |  irritable bowel syndrome  |  1
C0851578  |  sleep disorders  |  1
C0002020  |  alexithymia  |  1
C0011860  |  type 2 diabetes  |  1
C0024117  |  chronic obstructive pulmonary disease  |  1
C0600260  |  obstructive pulmonary disease  |  1
C0002766  |  analgesia  |  1
C0022116  |  ischemia  |  1
C0497327  |  dementia  |  1
C0020538  |  high blood pressure  |  1
C0151744  |  myocardial ischemia  |  1
C0021364  |  male infertility  |  1
C0007222  |  cardiovascular diseases  |  1
C0042373  |  vascular diseases  |  1
C0013537  |  eclampsia  |  1
Curated Gene
Entrez_id | Symbol | Resource(Total Genes:7)
FAM49B  |  51571  |  GWASCAT
LGR6  |  59352  |  GWASCAT
TLL1  |  7092  |  GWASCAT
ADCY8  |  114  |  GWASCAT
TBC1D2  |  55357  |  GWASCAT
PTPRVP  |  148713  |  GWASCAT
PRTFDC1  |  56952  |  GWASCAT
Inferring Gene
Entrez_id | Symbol | Resource(Total Genes:7)
1813  |  DRD2  |  infer
2289  |  FKBP5  |  infer
6531  |  SLC6A3  |  infer
6532  |  SLC6A4  |  infer
2562  |  GABRB3  |  infer
4129  |  MAOB  |  infer
2908  |  NR3C1  |  infer
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:331)
27184  |  DISC2  |  DISEASES
2288  |  FKBP4  |  DISEASES
6344  |  SCTR  |  DISEASES
7092  |  TLL1  |  DISEASES
51052  |  PRLH  |  DISEASES
1815  |  DRD4  |  DISEASES
4713  |  NDUFB7  |  DISEASES
7494  |  XBP1  |  DISEASES
5816  |  PVALB  |  DISEASES
6554  |  SLC10A1  |  DISEASES
10278  |  EFS  |  DISEASES
1457  |  CSNK2A1  |  DISEASES
5173  |  PDYN  |  DISEASES
5020  |  OXT  |  DISEASES
6530  |  SLC6A2  |  DISEASES
6822  |  SULT2A1  |  DISEASES
7392  |  USF2  |  DISEASES
64111  |  NPVF  |  DISEASES
113263  |  GLCCI1  |  DISEASES
4232  |  MEST  |  DISEASES
10014  |  HDAC5  |  DISEASES
51056  |  LAP3  |  DISEASES
4848  |  CNOT2  |  DISEASES
55907  |  CMAS  |  DISEASES
1839  |  HBEGF  |  DISEASES
3003  |  GZMK  |  DISEASES
2908  |  NR3C1  |  DISEASES
374291  |  NDUFS7  |  DISEASES
5507  |  PPP1R3C  |  DISEASES
1958  |  EGR1  |  DISEASES
5217  |  PFN2  |  DISEASES
4852  |  NPY  |  DISEASES
6718  |  AKR1D1  |  DISEASES
2166  |  FAAH  |  DISEASES
5740  |  PTGIS  |  DISEASES
5184  |  PEPD  |  DISEASES
56269  |  IRGC  |  DISEASES
80352  |  RNF39  |  DISEASES
26212  |  OR2B6  |  DISEASES
2354  |  FOSB  |  DISEASES
1446  |  CSN1S1  |  DISEASES
6495  |  SIX1  |  DISEASES
5300  |  PIN1  |  DISEASES
7166  |  TPH1  |  DISEASES
15  |  AANAT  |  DISEASES
57053  |  CHRNA10  |  DISEASES
9717  |  SEC14L5  |  DISEASES
348  |  APOE  |  DISEASES
59272  |  ACE2  |  DISEASES
51540  |  SCLY  |  DISEASES
1401  |  CRP  |  DISEASES
9695  |  EDEM1  |  DISEASES
80896  |  NPL  |  DISEASES
1329  |  COX5B  |  DISEASES
3569  |  IL6  |  DISEASES
2572  |  GAD2  |  DISEASES
1208  |  CLPS  |  DISEASES
91351  |  DDX60L  |  DISEASES
440279  |  UNC13C  |  DISEASES
3417  |  IDH1  |  DISEASES
4659  |  PPP1R12A  |  DISEASES
6095  |  RORA  |  DISEASES
3839  |  KPNA3  |  DISEASES
6532  |  SLC6A4  |  DISEASES
51433  |  ANAPC5  |  DISEASES
10728  |  PTGES3  |  DISEASES
1659  |  DHX8  |  DISEASES
4969  |  OGN  |  DISEASES
25939  |  SAMHD1  |  DISEASES
2033  |  EP300  |  DISEASES
3553  |  IL1B  |  DISEASES
23476  |  BRD4  |  DISEASES
51430  |  SUCO  |  DISEASES
26511  |  CHIC2  |  DISEASES
590  |  BCHE  |  DISEASES
2891  |  GRIA2  |  DISEASES
9759  |  HDAC4  |  DISEASES
5443  |  POMC  |  DISEASES
64083  |  GOLPH3  |  DISEASES
7375  |  USP4  |  DISEASES
4986  |  OPRK1  |  DISEASES
51083  |  GAL  |  DISEASES
55749  |  CCAR1  |  DISEASES
25996  |  REXO2  |  DISEASES
8620  |  NPFF  |  DISEASES
597  |  BCL2A1  |  DISEASES
4123  |  MAN2C1  |  DISEASES
4240  |  MFGE8  |  DISEASES
409  |  ARRB2  |  DISEASES
150094  |  SIK1  |  DISEASES
29947  |  DNMT3L  |  DISEASES
6531  |  SLC6A3  |  DISEASES
93650  |  ACPT  |  DISEASES
113091  |  PTH2  |  DISEASES
805  |  CALM2  |  DISEASES
5746  |  PTH2R  |  DISEASES
5868  |  RAB5A  |  DISEASES
90226  |  UCN2  |  DISEASES
8973  |  CHRNA6  |  DISEASES
9705  |  ST18  |  DISEASES
1392  |  CRH  |  DISEASES
4915  |  NTRK2  |  DISEASES
2904  |  GRIN2B  |  DISEASES
55768  |  NGLY1  |  DISEASES
60558  |  GUF1  |  DISEASES
2043  |  EPHA4  |  DISEASES
2911  |  GRM1  |  DISEASES
10428  |  CFDP1  |  DISEASES
55364  |  IMPACT  |  DISEASES
2890  |  GRIA1  |  DISEASES
7381  |  UQCRB  |  DISEASES
1142  |  CHRNB3  |  DISEASES
808  |  CALM3  |  DISEASES
6285  |  S100B  |  DISEASES
2905  |  GRIN2C  |  DISEASES
3060  |  HCRT  |  DISEASES
256471  |  MFSD8  |  DISEASES
4724  |  NDUFS4  |  DISEASES
54329  |  GPR85  |  DISEASES
6571  |  SLC18A2  |  DISEASES
64112  |  MOAP1  |  DISEASES
552  |  AVPR1A  |  DISEASES
1138  |  CHRNA5  |  DISEASES
4160  |  MC4R  |  DISEASES
7184  |  HSP90B1  |  DISEASES
6632  |  SNRPD1  |  DISEASES
762  |  CA4  |  DISEASES
80150  |  ASRGL1  |  DISEASES
4054  |  LTBP3  |  DISEASES
5368  |  PNOC  |  DISEASES
5617  |  PRL  |  DISEASES
43  |  ACHE  |  DISEASES
51181  |  DCXR  |  DISEASES
23244  |  PDS5A  |  DISEASES
6869  |  TACR1  |  DISEASES
340024  |  SLC6A19  |  DISEASES
154  |  ADRB2  |  DISEASES
2525  |  FUT3  |  DISEASES
2915  |  GRM5  |  DISEASES
2353  |  FOS  |  DISEASES
147  |  ADRA1B  |  DISEASES
255239  |  ANKK1  |  DISEASES
10886  |  NPFFR2  |  DISEASES
79660  |  PPP1R3B  |  DISEASES
23536  |  ADAT1  |  DISEASES
9610  |  RIN1  |  DISEASES
407  |  ARR3  |  DISEASES
7368  |  UGT8  |  DISEASES
11007  |  CCDC85B  |  DISEASES
10327  |  AKR1A1  |  DISEASES
8557  |  TCAP  |  DISEASES
55584  |  CHRNA9  |  DISEASES
57101  |  ANO2  |  DISEASES
1831  |  TSC22D3  |  DISEASES
4728  |  NDUFS8  |  DISEASES
3350  |  HTR1A  |  DISEASES
3291  |  HSD11B2  |  DISEASES
9377  |  COX5A  |  DISEASES
1960  |  EGR3  |  DISEASES
56952  |  PRTFDC1  |  DISEASES
57722  |  IGDCC4  |  DISEASES
6863  |  TAC1  |  DISEASES
7156  |  TOP3A  |  DISEASES
3309  |  HSPA5  |  DISEASES
5021  |  OXTR  |  DISEASES
3628  |  INPP1  |  DISEASES
22916  |  NCBP2  |  DISEASES
1812  |  DRD1  |  DISEASES
284359  |  IZUMO1  |  DISEASES
706  |  TSPO  |  DISEASES
121278  |  TPH2  |  DISEASES
6906  |  SERPINA7  |  DISEASES
277  |  AMY1B  |  DISEASES
3418  |  IDH2  |  DISEASES
23545  |  ATP6V0A2  |  DISEASES
2903  |  GRIN2A  |  DISEASES
348235  |  SKA2  |  DISEASES
3840  |  KPNA4  |  DISEASES
118987  |  PDZD8  |  DISEASES
10810  |  WASF3  |  DISEASES
3320  |  HSP90AA1  |  DISEASES
887  |  CCKBR  |  DISEASES
55727  |  BTBD7  |  DISEASES
885  |  CCK  |  DISEASES
4987  |  OPRL1  |  DISEASES
3988  |  LIPA  |  DISEASES
4842  |  NOS1  |  DISEASES
8165  |  AKAP1  |  DISEASES
57142  |  RTN4  |  DISEASES
3363  |  HTR7  |  DISEASES
2289  |  FKBP5  |  DISEASES
3266  |  ERAS  |  DISEASES
4128  |  MAOA  |  DISEASES
1395  |  CRHR2  |  DISEASES
4306  |  NR3C2  |  DISEASES
84062  |  DTNBP1  |  DISEASES
1508  |  CTSB  |  DISEASES
79722  |  ANKRD55  |  DISEASES
6633  |  SNRPD2  |  DISEASES
3198  |  HOXA1  |  DISEASES
5348  |  FXYD1  |  DISEASES
2918  |  GRM8  |  DISEASES
3767  |  KCNJ11  |  DISEASES
4110  |  MAGEA11  |  DISEASES
3359  |  HTR3A  |  DISEASES
391189  |  OR11L1  |  DISEASES
283420  |  CLEC9A  |  DISEASES
219844  |  HYLS1  |  DISEASES
2555  |  GABRA2  |  DISEASES
23237  |  ARC  |  DISEASES
801  |  CALM1  |  DISEASES
10219  |  KLRG1  |  DISEASES
2917  |  GRM7  |  DISEASES
4111  |  MAGEA12  |  DISEASES
284521  |  OR2L13  |  DISEASES
2571  |  GAD1  |  DISEASES
163227  |  ZNF100  |  DISEASES
6364  |  CCL20  |  DISEASES
8936  |  WASF1  |  DISEASES
10814  |  CPLX2  |  DISEASES
57181  |  SLC39A10  |  DISEASES
127343  |  DMBX1  |  DISEASES
1312  |  COMT  |  DISEASES
4860  |  PNP  |  DISEASES
22871  |  NLGN1  |  DISEASES
23499  |  MACF1  |  DISEASES
4886  |  NPY1R  |  DISEASES
1813  |  DRD2  |  DISEASES
56259  |  CTNNBL1  |  DISEASES
9722  |  NOS1AP  |  DISEASES
2987  |  GUK1  |  DISEASES
6446  |  SGK1  |  DISEASES
22926  |  ATF6  |  DISEASES
844  |  CASQ1  |  DISEASES
5796  |  PTPRK  |  DISEASES
6281  |  S100A10  |  DISEASES
54964  |  C1orf56  |  DISEASES
6001  |  RGS10  |  DISEASES
5550  |  PREP  |  DISEASES
1268  |  CNR1  |  DISEASES
4803  |  NGF  |  DISEASES
3351  |  HTR1B  |  DISEASES
5956  |  OPN1LW  |  DISEASES
4646  |  MYO6  |  DISEASES
278  |  AMY1C  |  DISEASES
276  |  AMY1A  |  DISEASES
29944  |  PNMA3  |  DISEASES
115004  |  MB21D1  |  DISEASES
2258  |  FGF13  |  DISEASES
3062  |  HCRTR2  |  DISEASES
4774  |  NFIA  |  DISEASES
2902  |  GRIN1  |  DISEASES
23413  |  NCS1  |  DISEASES
79717  |  PPCS  |  DISEASES
2899  |  GRIK3  |  DISEASES
4674  |  NAP1L2  |  DISEASES
3061  |  HCRTR1  |  DISEASES
2170  |  FABP3  |  DISEASES
11130  |  ZWINT  |  DISEASES
2914  |  GRM4  |  DISEASES
8518  |  IKBKAP  |  DISEASES
55357  |  TBC1D2  |  DISEASES
56243  |  KIAA1217  |  DISEASES
11166  |  SOX21  |  DISEASES
1325  |  CORT  |  DISEASES
114798  |  SLITRK1  |  DISEASES
10590  |  SCGN  |  DISEASES
4129  |  MAOB  |  DISEASES
3356  |  HTR2A  |  DISEASES
2625  |  GATA3  |  DISEASES
92270  |  ATP6AP1L  |  DISEASES
551  |  AVP  |  DISEASES
8544  |  PIR  |  DISEASES
114131  |  UCN3  |  DISEASES
7054  |  TH  |  DISEASES
51109  |  RDH11  |  DISEASES
1814  |  DRD3  |  DISEASES
4336  |  MOBP  |  DISEASES
55022  |  PID1  |  DISEASES
9244  |  CRLF1  |  DISEASES
78996  |  C7orf49  |  DISEASES
196410  |  METTL7B  |  DISEASES
2719  |  GPC3  |  DISEASES
51520  |  LARS  |  DISEASES
64115  |  C10orf54  |  DISEASES
2912  |  GRM2  |  DISEASES
51343  |  FZR1  |  DISEASES
117  |  ADCYAP1R1  |  DISEASES
344148  |  NCKAP5  |  DISEASES
116372  |  LYPD1  |  DISEASES
100134934  |  TEN1  |  DISEASES
594857  |  NPS  |  DISEASES
1394  |  CRHR1  |  DISEASES
815  |  CAMK2A  |  DISEASES
1826  |  DSCAM  |  DISEASES
23077  |  MYCBP2  |  DISEASES
1135  |  CHRNA2  |  DISEASES
152  |  ADRA2C  |  DISEASES
10636  |  RGS14  |  DISEASES
84334  |  APOPT1  |  DISEASES
151  |  ADRA2B  |  DISEASES
1385  |  CREB1  |  DISEASES
348180  |  CTU2  |  DISEASES
6563  |  SLC14A1  |  DISEASES
4988  |  OPRM1  |  DISEASES
10163  |  WASF2  |  DISEASES
5999  |  RGS4  |  DISEASES
8848  |  TSC22D1  |  DISEASES
7124  |  TNF  |  DISEASES
9228  |  DLGAP2  |  DISEASES
5578  |  PRKCA  |  DISEASES
83871  |  RAB34  |  DISEASES
116  |  ADCYAP1  |  DISEASES
627  |  BDNF  |  DISEASES
1945  |  EFNA4  |  DISEASES
9217  |  VAPB  |  DISEASES
83939  |  EIF2A  |  DISEASES
346171  |  ZFP57  |  DISEASES
222659  |  PXT1  |  DISEASES
2939  |  GSTA2  |  DISEASES
100506742  |  CASP12  |  DISEASES
23286  |  WWC1  |  DISEASES
22999  |  RIMS1  |  DISEASES
9685  |  CLINT1  |  DISEASES
5099  |  PCDH7  |  DISEASES
8914  |  TIMELESS  |  DISEASES
91056  |  AP5B1  |  DISEASES
199777  |  ZNF626  |  DISEASES
104355217  |  ERICD  |  DISEASES
9299  |  SNORD30  |  DISEASES
116937  |  SNORD83A  |  DISEASES
Locus(Waiting for update.)
Disease ID 656
Disease post-traumatic stress disorder
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:41)
HP:0000716  |  Depression  |  16
HP:0012531  |  Pain  |  12
HP:0000739  |  Anxiety  |  9
HP:0100753  |  Schizophrenia  |  6
HP:0002360  |  Sleep disturbance  |  6
HP:0000718  |  Aggressive behaviour  |  5
HP:0100543  |  Cognitive deficits  |  4
HP:0000708  |  Behavioral problems  |  3
HP:0100033  |  Tic disorder  |  3
HP:0001297  |  Cerebral vascular events  |  2
HP:0002039  |  Anorexia  |  2
HP:0012125  |  Prostate cancer  |  2
HP:0001658  |  Myocardial infarction  |  2
HP:0002315  |  Headaches  |  2
HP:0012075  |  Personality disorder  |  2
HP:0003002  |  Breast carcinoma  |  2
HP:0003418  |  Back pain  |  2
HP:0012532  |  Chronic pain  |  2
HP:0000789  |  Infertility  |  2
HP:0002076  |  Migraine headaches  |  2
HP:0010677  |  Enuresis nocturna  |  1
HP:0000805  |  Enuresis  |  1
HP:0000756  |  Fear of open spaces  |  1
HP:0008760  |  Violent behavior  |  1
HP:0001262  |  Somnolence  |  1
HP:0030833  |  Neck pain  |  1
HP:0100716  |  Autoagression  |  1
HP:0003251  |  Male infertility  |  1
HP:0100699  |  Scarring  |  1
HP:0012167  |  Trichotillomania  |  1
HP:0003419  |  Low back pain  |  1
HP:0002059  |  Degeneration of cerebrum  |  1
HP:0000713  |  Agitation  |  1
HP:0002099  |  Asthma  |  1
HP:0100785  |  Insomnia  |  1
HP:0001268  |  Mental deterioration  |  1
HP:0006510  |  Chronic obstructive pulmonary disease  |  1
HP:0001518  |  Small for gestational age  |  1
HP:0100602  |  Pre-eclampsia  |  1
HP:0100601  |  Eclampsia  |  1
HP:0000726  |  Dementia  |  1
Disease ID 656
Disease post-traumatic stress disorder
Manually Symptom(Waiting for update.)
Text Mined Symptom
UMLS | Name | Sentences' Count(Total Symptoms:13)
C0003467  |  anxiety  |  9
C0231303  |  distress  |  8
C0037317  |  sleep disturbance  |  5
C0003469  |  anxiety disorders  |  3
C0871189  |  psychotic symptoms  |  2
C0004936  |  mental disorders  |  2
C0002766  |  analgesia  |  1
C0037317  |  sleep disturbances  |  1
C0851578  |  sleep disorders  |  1
C0236720  |  flashbacks  |  1
C0002020  |  alexithymia  |  1
C0422833  |  ent symptoms  |  1
C0917801  |  insomnia  |  1
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:32)
snpId pubmedId geneId geneSymbol diseaseId sourceId sentence score Year geneSymbol_dbSNP CHROMOSOME POS REF ALT
rs10055255240752951392CRHumls:C0038436BeFreeTo determine if single nucleotide polymorphisms of the corticotrophin-releasing hormone binding protein (CRHBP, rs10055255) and CRH receptor type 1 (CRHR1, rs1876831) were associated with posttraumatic stress disorder (PTSD) and depressive symptoms following medical-surgical intensive care unit (ICU) hospitalization.0.0008143262013CRHBP576968168AT
rs10055255240752951394CRHR1umls:C0038436BeFreeTo determine if single nucleotide polymorphisms of the corticotrophin-releasing hormone binding protein (CRHBP, rs10055255) and CRH receptor type 1 (CRHR1, rs1876831) were associated with posttraumatic stress disorder (PTSD) and depressive symptoms following medical-surgical intensive care unit (ICU) hospitalization.0.0013572092013CRHBP576968168AT
rs10339622545634656952PRTFDC1umls:C0038436GWASCATGenomic predictors of combat stress vulnerability and resilience in U.S. Marines: A genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene.0.1202714422014PRTFDC11024927877CT
rs1360780249598962908NR3C1umls:C0038436BeFreeAs FKBP5 single-nucleotide polymorphism rs1360780 has a putative functional role in the regulation of FKBP5 expression and GR sensitivity, we hypothesized that this polymorphism influences PTSD treatment success.0.0851573962014FKBP5;LOC105375032635639794TC
rs1360780253316392289FKBP5umls:C0038436BeFreeThe common single nucleotide polymorphism (SNP) rs1360780 (C/T) of the FK506 Binding Protein 5 (FKBP5) gene has been reported to be associated with an altered response of the hypothalamic-pituitary-adrenal (HPA) axis and the development of stress-related psychiatric disorders such as posttraumatic stress disorder (PTSD).0.0072529862014FKBP5;LOC105375032635639794TC
rs1387923175707384915NTRK2umls:C0038436BeFreeUsing q-value analysis for multiplicity correction, we found significant interactions between lithium response and SNPs (rs1387923 and rs1565445) in the gene encoding neurotrophic tyrosine kinase receptor type 2 (NTRK2) and suicidal ideation, and between SNP rs2064721 in the gene encoding inositol polyphosphate-1-phosphatase (INPP1) and post-traumatic stress disorder.0.0802714422007NTRK2985025721AG
rs1387923175707383628INPP1umls:C0038436BeFreeUsing q-value analysis for multiplicity correction, we found significant interactions between lithium response and SNPs (rs1387923 and rs1565445) in the gene encoding neurotrophic tyrosine kinase receptor type 2 (NTRK2) and suicidal ideation, and between SNP rs2064721 in the gene encoding inositol polyphosphate-1-phosphatase (INPP1) and post-traumatic stress disorder.0.0002714422007NTRK2985025721AG
rs1565445175707383628INPP1umls:C0038436BeFreeUsing q-value analysis for multiplicity correction, we found significant interactions between lithium response and SNPs (rs1387923 and rs1565445) in the gene encoding neurotrophic tyrosine kinase receptor type 2 (NTRK2) and suicidal ideation, and between SNP rs2064721 in the gene encoding inositol polyphosphate-1-phosphatase (INPP1) and post-traumatic stress disorder.0.0002714422007NTRK2985002156GA
rs1565445175707384915NTRK2umls:C0038436BeFreeUsing q-value analysis for multiplicity correction, we found significant interactions between lithium response and SNPs (rs1387923 and rs1565445) in the gene encoding neurotrophic tyrosine kinase receptor type 2 (NTRK2) and suicidal ideation, and between SNP rs2064721 in the gene encoding inositol polyphosphate-1-phosphatase (INPP1) and post-traumatic stress disorder.0.0802714422007NTRK2985002156GA
rs169041792372651151571FAM49Bumls:C0038436GWASCATGenome-wide association study identifies new susceptibility loci for posttraumatic stress disorder.0.122013FAM49B8129946705GA
rs16965628215457246532SLC6A4umls:C0038436BeFreeThe SLC6A4 SNP rs16965628 and 5-HTTLPR are associated with a bias in neural responses to traumatic reminders and cognitive control of emotions in patients with PTSD.0.0165256172011SLC6A41730228407GC
rs1876831240752951394CRHR1umls:C0038436BeFreeTo determine if single nucleotide polymorphisms of the corticotrophin-releasing hormone binding protein (CRHBP, rs10055255) and CRH receptor type 1 (CRHR1, rs1876831) were associated with posttraumatic stress disorder (PTSD) and depressive symptoms following medical-surgical intensive care unit (ICU) hospitalization.0.0013572092013CRHR1;MGC57346-CRHR1;LOC1053718011745830379CT
rs1876831240752951392CRHumls:C0038436BeFreeTo determine if single nucleotide polymorphisms of the corticotrophin-releasing hormone binding protein (CRHBP, rs10055255) and CRH receptor type 1 (CRHR1, rs1876831) were associated with posttraumatic stress disorder (PTSD) and depressive symptoms following medical-surgical intensive care unit (ICU) hospitalization.0.0008143262013CRHR1;MGC57346-CRHR1;LOC1053718011745830379CT
rs2064721175707384915NTRK2umls:C0038436BeFreeUsing q-value analysis for multiplicity correction, we found significant interactions between lithium response and SNPs (rs1387923 and rs1565445) in the gene encoding neurotrophic tyrosine kinase receptor type 2 (NTRK2) and suicidal ideation, and between SNP rs2064721 in the gene encoding inositol polyphosphate-1-phosphatase (INPP1) and post-traumatic stress disorder.0.0802714422007AGPAT46161187984TC
rs2064721175707383628INPP1umls:C0038436BeFreeUsing q-value analysis for multiplicity correction, we found significant interactions between lithium response and SNPs (rs1387923 and rs1565445) in the gene encoding neurotrophic tyrosine kinase receptor type 2 (NTRK2) and suicidal ideation, and between SNP rs2064721 in the gene encoding inositol polyphosphate-1-phosphatase (INPP1) and post-traumatic stress disorder.0.0002714422007AGPAT46161187984TC
rs226773523505260117ADCYAP1R1umls:C0038436BeFree(2011); Nature 470:492-497] demonstrated that a variant, rs2267735, in the gene encoding PAC1 (ADCYAP1R1) is associated with post-traumatic stress disorder (PTSD) in a primarily African-American cohort of highly traumatized females.0.0016286512013ADCYAP1R1731095890CG
rs25531218188276532SLC6A4umls:C0038436BeFreeThe relationship between combat-related posttraumatic stress disorder and the 5-HTTLPR/rs25531 polymorphism.0.0165256172011SLC6A4;LOC1053717201730237328TC
rs26323224677629114ADCY8umls:C0038436GWASCATA genome-wide association study of clinical symptoms of dissociation in a trauma-exposed sample.0.122014ADCY88130795923CA
rs31001272545634659352LGR6umls:C0038436GWASCATGenomic predictors of combat stress vulnerability and resilience in U.S. Marines: A genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene.0.122014NA1202191842CA
rs38660211816649215627BDNFumls:C0038436BeFreeThis variant and two previously reported BDNF SNPs (C270T and Val66Met) were genotyped in 295 patients with AD, 108 with AFDs, 96 with posttraumatic stress disorder (PTSD), 84 with schizophrenia, 327 with alcohol and/or drug dependence, and 250 normal control subjects.0.0027144192006NANANANANA
rs38660211823312562627BDNFumls:C0038436BeFreeThe brain-derived neurotrophic factor Val66Met polymorphism predicts response to exposure therapy in posttraumatic stress disorder.0.0027144192013NANANANANA
rs38660211821728904627BDNFumls:C0038436BeFreeThe association between brain-derived neurotrophic factor Val66Met variants and psychotic symptoms in posttraumatic stress disorder.0.0027144192012NANANANANA
rs38660211820955337627BDNFumls:C0038436BeFreeVariant brain-derived neurotrophic factor Val66Met endophenotypes: implications for posttraumatic stress disorder.0.0027144192010NANANANANA
rs38660211821491204627BDNFumls:C0038436BeFreeThe objective of the present study was to identify, in a case-control study, whether the brain-derived neurotrophic factor (BDNF) val66met polymorphism (rs6265), the dopamine transporter (DAT1) three prime untranslated region (3'UTR) variable number of tandem repeats (VNTR), and the serotonin transporter (5-HTTPRL) short/long variants are associated with the development of PTSD in a group of victims of urban violence.0.0027144192011NANANANANA
rs386602118231035491813DRD2umls:C0038436BeFreeBDNF Val66Met and DRD2 Taq1A polymorphisms interact to influence PTSD symptom severity: a preliminary investigation in a South African population.0.0071770412013NANANANANA
rs451118025456346148713PTPRVPumls:C0038436GWASCATGenomic predictors of combat stress vulnerability and resilience in U.S. Marines: A genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene.0.122014PTPRVP1202180311AG
rs4680217831751312COMTumls:C0038436BeFreeCatechol-O-methyltransferase Val158Met polymorphism moderates anterior cingulate volume in posttraumatic stress disorder.0.0013572092011COMT;MIR47612219963748GA
rs4680199444091312COMTumls:C0038436BeFreeThe risk of posttraumatic stress disorder after trauma depends on traumatic load and the catechol-o-methyltransferase Val(158)Met polymorphism.0.0013572092010COMT;MIR47612219963748GA
rs626521491204627BDNFumls:C0038436BeFreeThe objective of the present study was to identify, in a case-control study, whether the brain-derived neurotrophic factor (BDNF) val66met polymorphism (rs6265), the dopamine transporter (DAT1) three prime untranslated region (3'UTR) variable number of tandem repeats (VNTR), and the serotonin transporter (5-HTTPRL) short/long variants are associated with the development of PTSD in a group of victims of urban violence.0.0027144192011BDNF;BDNF-AS1127658369CT
rs6277188335811813DRD2umls:C0038436GAD[The DRD2 gene 957C>T polymorphism is associated with posttraumatic stress disorder in war veterans.]0.0071770412009DRD211113412737GA
rs6812849237265117092TLL1umls:C0038436GWASCATThis study identified TLL1 as a new susceptibility gene for PTSD.0.122013TLL14165951384CA
rs78663502611422955357TBC1D2umls:C0038436GWASCATGenome-wide association study of posttraumatic stress disorder in a cohort of Iraq-Afghanistan era veterans.0.122015TBC1D2998221544CG,T
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:164)
CHR POS SNPID REF ALT ORI_SNPID PMID P_VALUE P_VALUE_TEXT OR/BETA CI95_TEXT GWAS_INITIAL_SAMPLE_SIZE SUB_POPULATION SUPER_POPULATION GWAS_TRAIT HPO_ID HPO_TERM DO_ID DO_TERM MESH_ID MESH_TERM EFO_ID EFO_TERM DOLITE_TERM RISK_ALLELE PUBLICATION_TYPE AA GENE_SYMBOL TYPE REFGENE
112194451rs1148472TCrs1148472228690350.0000922NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
140222660rs7553968GCrs7553968228690350.0000882NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
174898117rs477159GArs477159228690350.0000338NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.A
174899573rs792884TGrs792884228690350.0000157NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
174900897rs643371ACrs643371228690350.0000987NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
174907316rs1325604GArs1325604228690350.000085NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
1154713341rs1506985TCrs1506985228690350.0000466NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.A
1154714006rs4999127GArs4999127228690350.0000206NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.A
1232444455rs9725031CTrs9725031246776298.00E-06NA1.13[0.64-1.62] unit increase484 European ancestry trauma-exposed individualsEuropean(484)ALL(484)EUR(484)ALL(484)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
1238573691rs1021356AGrs1021356228690350.0000049NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
1238574814rs6662339CTrs6662339228690350.0000423NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
1238575717rs6689284GArs6689284228690350.0000315NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.A
1238575867rs6665978CTrs6665978228690350.0000315NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
1238576614rs12118091TGrs12118091228690350.0000049NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
1238576715rs113508478CTrs113508478228690350.0000074NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
1238576715rs113508478CTrs147773561228690350.00000735NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
1242603059rs2055536AGrs2055536228690350.0000996NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
1242603249rs2810030GArs2810030228690350.0000971NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
1244015993rs4430311CTrs4430311237265116.00E-06Trauma exposed controls; EANANAup to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controlsAfrican American(3392)European(1846)ALL(5238)AFR(3392)EUR(1846)ALL(5238)Post-traumatic stress disorder (asjusted for relatedness)HPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
25925857rs1560238CTrs1560238228690350.0000174NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.A
25926156rs16864200CTrs16864200228690350.0000169NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
25928093rs16864209TCrs16864209228690350.0000169NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
227743423rs11681351GArs11681351228690350.000077NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
227746832rs8179252ACrs8179252228690350.000077NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.A
227794233rs10205364CTrs10205364228690350.0000912NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
227801403rs1919125CGrs1919125228690350.000093NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
227801418rs1919126CArs1919126228690350.0000902NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.A
227807624rs13026621GArs13026621228690350.0000902NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.A
227855239rs4666005AGrs4666005228690350.0000683NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
227857517rs1528402GArs1528402228690350.0000298NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.A
274463566rs13006863CTrs13006863237265113.00E-06Whole cohort; AANANAup to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controlsAfrican American(3392)European(1846)ALL(5238)AFR(3392)EUR(1846)ALL(5238)Post-traumatic stress disorder (asjusted for relatedness)HPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
2188814444rs10170218ACrs10170218240801875.10E-08GWAS stage only2.89[1.97-4.23]81 African American female cases; 261 African American female controls; 10 European ancestry female cases; 35 European ancestry female controls; 3 female cases; 22 female controlsNOPOP(25)European(45)African American(342)ALL(412)NOPOP(25)AFR(342)EUR(45)ALL(412)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumatic
2202122995rs3769823AGrs3769823228690350.0000488NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
2202151163rs3769818AGrs3769818228690350.0000334NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
2202153225rs700635CArs700635228690350.0000334NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.A
2202153684rs6714430CTrs6714430228690350.0000334NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
320083881rs1915919CTrs1915919246776298.00E-06NA0.74[0.43-1.05] unit increase484 European ancestry trauma-exposed individualsEuropean(484)ALL(484)EUR(484)ALL(484)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
364617070rs6445420CTrs6445420228690350.0000967NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
3107640533rs13086279GArs13086279228690350.0000929NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
3178782021rs4955793CTrs4955793237265112.00E-06Whole cohort; AANANAup to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controlsAfrican American(3392)European(1846)ALL(5238)AFR(3392)EUR(1846)ALL(5238)Post-traumatic stress disorder (asjusted for relatedness)HPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
458080251rs6850123CTrs6850123228690350.0000749NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
458081590rs1860623AGrs1860623228690350.000086NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
465392212rs1425392TCrs1425392237265117.00E-06Trauma exposed controls; EANANAup to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controlsAfrican American(3392)European(1846)ALL(5238)AFR(3392)EUR(1846)ALL(5238)Post-traumatic stress disorder (asjusted for relatedness)HPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
4122445005rs7673847TCrs7673847228690350.0000621NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
4122446695rs200748952GTrs142186713228690350.0000966NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
4122446695rs35950299GGTrs142186713228690350.0000966NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
4122446695rs397878254GGTrs142186713228690350.0000966NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
4166865585rs7691872GTrs7691872237265111.22E-07Whole cohort; EANANA300 European ancestry cases; up to 1,538 European ancestry controls; 444 African American cases; up to 2,936 African American controlsAfrican American(3380)European(1838)ALL(5218)AFR(3380)EUR(1838)ALL(5218)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
4166872536rs6812849CArs6812849237265111.00E-06Trauma Exposed controls; EANANA300 European ancestry cases; up to 1,538 European ancestry controls; 444 African American cases; up to 2,936 African American controlsAfrican American(3380)European(1838)ALL(5218)AFR(3380)EUR(1838)ALL(5218)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
4166872536rs6812849CArs6812849237265111.00E-07Whole cohort; EANANAup to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controlsAfrican American(3392)European(1846)ALL(5238)AFR(3392)EUR(1846)ALL(5238)Post-traumatic stress disorder (asjusted for relatedness)HPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
4166872536rs6812849CArs6812849237265113.00E-09Whole cohort; EANANA300 European ancestry cases; up to 1,538 European ancestry controls; 444 African American cases; up to 2,936 African American controlsAfrican American(3380)European(1838)ALL(5218)AFR(3380)EUR(1838)ALL(5218)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
4166872536rs6812849CArs6812849237265115.00E-07Trauma exposed controls; EANANAup to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controlsAfrican American(3392)European(1846)ALL(5238)AFR(3392)EUR(1846)ALL(5238)Post-traumatic stress disorder (asjusted for relatedness)HPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
4187719659rs7698529GArs7698529228690350.0000795NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.A
4187722479rs11132409CTrs11132409228690350.0000989NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
517761225rs11959046GArs11959046228690350.0000816NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
5146610829rs31031TCrs31031228690350.0000168NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
5171474120rs6892217CTrs6892217228690350.0000781NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
5178897590rs4701170GArs4701170240801877.92E-06GWAS stage only2.41[1.66-3.51]81 African American female cases; 261 African American female controls; 10 European ancestry female cases; 35 European ancestry female controls; 3 female cases; 22 female controlsNOPOP(25)European(45)African American(342)ALL(412)NOPOP(25)AFR(342)EUR(45)ALL(412)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumatic
625219582rs77006546TCrs77006546246776299.60E-06NA1.7[0.96-1.7] unit increase484 European ancestry trauma-exposed individualsEuropean(484)ALL(484)EUR(484)ALL(484)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
629809382rs1611133CTrs1611133240801871.18E-06GWAS stage only3.56[2.04-6.22]81 African American female cases; 261 African American female controls; 10 European ancestry female cases; 35 European ancestry female controls; 3 female cases; 22 female controlsNOPOP(25)European(45)African American(342)ALL(412)NOPOP(25)AFR(342)EUR(45)ALL(412)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumatic
631045554rs9378152CGrs9378152228690350.0000492NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
631049655rs9380215GArs9380215228690350.0000374NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
631055018rs12527394GArs12527394228690350.0000376NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
631058178rs4947296TCrs4947296228690350.0000374NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
631070522rs9394037GArs9394037228690350.0000241NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
631074128rs4947302CTrs4947302228690350.0000526NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
631074148rs4947246GTrs4947246228690350.0000511NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
631077405rs9391709GCrs9391709228690350.0000511NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
631079264rs2233984CTrs2233984228690350.0000511NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
633917711rs10947469GArs10947469228690350.0000889NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
643900443rs833621TCrs833621228690350.0000206NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.A
682933309rs9361904CTrs9361904228690350.0000795NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
6138484125rs72986828TGrs72986828228690350.0000056NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
6138484764rs6907714AGrs6907714228690350.0000203NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
6156320573rs4869880CTrs4869880228690350.0000933NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T,C
73179991rs7779245TCrs7779245228690350.0000978NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
73180657rs6964682CTrs6964682228690350.0000802NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
716556076rs57025232TCrs57025232228690350.0000587NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
752006415rs406001TCrs406001237265112.00E-08Whole cohort; EANANAup to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controlsAfrican American(3392)European(1846)ALL(5238)AFR(3392)EUR(1846)ALL(5238)Post-traumatic stress disorder (asjusted for relatedness)HPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
752006415rs406001TCrs406001237265112.77E-04Whole cohort; EANANA300 European ancestry cases; up to 1,538 European ancestry controls; 444 African American cases; up to 2,936 African American controlsAfrican American(3380)European(1838)ALL(5218)AFR(3380)EUR(1838)ALL(5218)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
752006415rs406001TCrs406001237265113.00E-08Trauma exposed controls; EANANAup to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controlsAfrican American(3392)European(1846)ALL(5238)AFR(3392)EUR(1846)ALL(5238)Post-traumatic stress disorder (asjusted for relatedness)HPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
752008734rs450378CTrs450378237265112.03E-04Whole cohort; EANANA300 European ancestry cases; up to 1,538 European ancestry controls; 444 African American cases; up to 2,936 African American controlsAfrican American(3380)European(1838)ALL(5218)AFR(3380)EUR(1838)ALL(5218)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
752008734rs450378CTrs450378237265115.59E-04Trauma exposed controls; EANANA300 European ancestry cases; up to 1,538 European ancestry controls; 444 African American cases; up to 2,936 African American controlsAfrican American(3380)European(1838)ALL(5218)AFR(3380)EUR(1838)ALL(5218)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
777985864rs4730234TCrs4730234228690350.0000725NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
777988279rs12670218CTrs12670218228690350.0000877NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
782646210rs28156TCrs28156228690350.000044NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
7112130009rs11767398ACrs11767398240801875.95E-06GWAS stage only2.54[1.71-3.78]81 African American female cases; 261 African American female controls; 10 European ancestry female cases; 35 European ancestry female controls; 3 female cases; 22 female controlsNOPOP(25)European(45)African American(342)ALL(412)NOPOP(25)AFR(342)EUR(45)ALL(412)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumatic
7154592866rs71534169TGrs71534169246776294.00E-06NA1.63[0.94-2.32] unit increase484 European ancestry trauma-exposed individualsEuropean(484)ALL(484)EUR(484)ALL(484)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
86715719rs2980946ACrs2980946228690350.0000757NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
812808108rs62488971CTrs62488971246776298.37E-06NA1.58[0.89-1.58] unit increase484 European ancestry trauma-exposed individualsEuropean(484)ALL(484)EUR(484)ALL(484)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
812834600rs2460905GArs2460905246776295.00E-06NA1.38[0.79-1.97] unit increase484 European ancestry trauma-exposed individualsEuropean(484)ALL(484)EUR(484)ALL(484)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
812866004rs2466273ACrs2466273246776297.10E-06NA1.31[0.74-1.31] unit increase484 European ancestry trauma-exposed individualsEuropean(484)ALL(484)EUR(484)ALL(484)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
827073268rs1446684ACrs1446684228690350.0000821NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
831448469rs13258147GArs13258147228690350.0000878NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
841228458rs10958680CTrs10958680228690350.0000981NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
841231950rs2883471CTrs2883471228690350.0000236NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G,A
882069207rs11988289ACrs11988289228690350.0000286NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.A
8115578307rs7014900TGrs7014900237265111.31E-04Whole cohort; AANANA300 European ancestry cases; up to 1,538 European ancestry controls; 444 African American cases; up to 2,936 African American controlsAfrican American(3380)European(1838)ALL(5218)AFR(3380)EUR(1838)ALL(5218)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
8115578307rs7014900TGrs7014900237265112.00E-06Whole cohort; AANANAup to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controlsAfrican American(3392)European(1846)ALL(5238)AFR(3392)EUR(1846)ALL(5238)Post-traumatic stress disorder (asjusted for relatedness)HPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
8115578307rs7014900TGrs7014900237265113.90E-04Trauma exposed controls; AANANA300 European ancestry cases; up to 1,538 European ancestry controls; 444 African American cases; up to 2,936 African American controlsAfrican American(3380)European(1838)ALL(5218)AFR(3380)EUR(1838)ALL(5218)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
8115578307rs7014900TGrs7014900237265114.00E-06Trauma exposed controls; AANANAup to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controlsAfrican American(3392)European(1846)ALL(5238)AFR(3392)EUR(1846)ALL(5238)Post-traumatic stress disorder (asjusted for relatedness)HPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
8122948438rs12676697TCrs12676697228690350.0000939NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
8130958951rs16904179GArs16904179237265117.00E-07Whole cohort; AANANAup to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controlsAfrican American(3392)European(1846)ALL(5238)AFR(3392)EUR(1846)ALL(5238)Post-traumatic stress disorder (asjusted for relatedness)HPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
8131808169rs263232CArs263232246776296.00E-07NA1.43[0.88-1.98] unit increase484 European ancestry trauma-exposed individualsEuropean(484)ALL(484)EUR(484)ALL(484)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
8134270548rs2272651TCrs2272651237265113.00E-06Whole cohort; EANANAup to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controlsAfrican American(3392)European(1846)ALL(5238)AFR(3392)EUR(1846)ALL(5238)Post-traumatic stress disorder (asjusted for relatedness)HPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
8134270548rs2272651TCrs2272651237265115.36E-05Whole cohort; EANANA300 European ancestry cases; up to 1,538 European ancestry controls; 444 African American cases; up to 2,936 African American controlsAfrican American(3380)European(1838)ALL(5218)AFR(3380)EUR(1838)ALL(5218)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
8144231514rs4977138AGrs4977138228690350.0000697NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
8144234489rs6420183CTrs6420183228690350.0000414NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
92289519rs7861374CArs7861374228690350.0000708NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.A
92299220rs10965506TGrs10965506228690350.0000812NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
92300565rs13292475TCrs13292475228690350.0000624NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
92301724rs13294267AGrs13294267228690350.000044NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.A
98709838rs16928304AGrs16928304228690350.0000653NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
980997705rs2989585AGrs2989585228690350.0000738NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
9101253226rs2779551TCrs2779551237265112.00E-06Whole cohort; EANANAup to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controlsAfrican American(3392)European(1846)ALL(5238)AFR(3392)EUR(1846)ALL(5238)Post-traumatic stress disorder (asjusted for relatedness)HPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
9111936128rs7858727CArs7858727228690350.0000185NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
9111938125rs10119402GTrs10119402228690350.0000132NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
9111945049rs3750450TGrs3750450228690350.0000897NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.A
9111958345rs6415807GArs6415807228690350.0000131NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.A
1057549296rs16907840CTrs16907840237265118.00E-06Whole cohort; EANANAup to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controlsAfrican American(3392)European(1846)ALL(5238)AFR(3392)EUR(1846)ALL(5238)Post-traumatic stress disorder (asjusted for relatedness)HPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
1063678484rs77968426CTrs77968426228690350.0000435NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
1087608460rs7076096CTrs7076096237265115.00E-06Trauma exposed controls; AANANAup to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controlsAfrican American(3392)European(1846)ALL(5238)AFR(3392)EUR(1846)ALL(5238)Post-traumatic stress disorder (asjusted for relatedness)HPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
1090985948rs2254747CTrs2254747228690350.0000635NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
10126073849rs870209CTrs870209228690350.0000757NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
1187949532rs682457TCrs682457246776291.00E-06NA1.11[0.68-1.54] unit increase484 European ancestry trauma-exposed individualsEuropean(484)ALL(484)EUR(484)ALL(484)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
1199629201rs1219050GArs1219050228690350.000079NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
1295119816rs7302717TCrs7302717240801875.72E-06GWAS stage only2.44[1.67-3.57]81 African American female cases; 261 African American female controls; 10 European ancestry female cases; 35 European ancestry female controls; 3 female cases; 22 female controlsNOPOP(25)European(45)African American(342)ALL(412)NOPOP(25)AFR(342)EUR(45)ALL(412)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumatic
12108167002rs57043169AC,Grs57043169228690350.0000708NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.A
13114886976rs9525275TCrs9525275228690350.0000199NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
1424878485rs12897153GArs12897153228690350.0000784NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
1449426842rs7158872GTrs7158872237265112.00E-06Whole cohort; AANANAup to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controlsAfrican American(3392)European(1846)ALL(5238)AFR(3392)EUR(1846)ALL(5238)Post-traumatic stress disorder (asjusted for relatedness)HPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
1449426842rs7158872GTrs7158872237265113.00E-06Trauma exposed controls; AANANAup to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controlsAfrican American(3392)European(1846)ALL(5238)AFR(3392)EUR(1846)ALL(5238)Post-traumatic stress disorder (asjusted for relatedness)HPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
1469789755rs3902951TGrs3902951228690350.0000825NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.A
1555352945rs1528462CTrs1528462228690350.000058NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
1560801066rs16942660CTrs16942660228690350.0009NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
1561103590rs341366AGrs341366228690350.0000373NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.A
1561109318rs2414681CArs2414681228690350.00005NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
1561109873rs10519074CArs10519074228690350.0000154NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
1561114104rs7169281TCrs7169281228690350.0000295NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T,C
1561124838rs8041061GTrs8041061228690350.00000016NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
1561124953rs8042149TGrs8042149228690352.49E-08NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
1561126859rs4775301TCrs4775301228690350.000000459NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
1561130639rs8024133CTrs8024133228690350.000000877NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
1561131683rs11071561TArs11071561228690350.0000038NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.A
1561132845rs341401GArs341401228690350.000062NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
1561433543rs11071587GArs11071587228690350.00011NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
1561433578rs11071588TGrs11071588228690350.0000677NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
1582193846rs77963519GArs77963519246776294.00E-06NA1.56[0.91-2.21] unit increase484 European ancestry trauma-exposed individualsEuropean(484)ALL(484)EUR(484)ALL(484)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
17258914rs9895447GArs9895447228690350.0000112NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
17259248rs71355256CTrs71355256228690350.00000428NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
17266655rs67288608GCrs67288608228690350.0000116NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
17273298rs6565727GArs6565727228690350.0000132NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
178905016rs7219148TGrs7219148228690350.0000506NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
1726686445rs17802736AGrs17802736228690350.0000968NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.A
1731659032rs76604546TArs76604546228690350.0000718NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
1764447165rs7207499GArs7207499237265115.00E-06Whole cohort; AANANAup to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controlsAfrican American(3392)European(1846)ALL(5238)AFR(3392)EUR(1846)ALL(5238)Post-traumatic stress disorder (asjusted for relatedness)HPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
1836040352rs10502692CTrs10502692240801874.46E-06GWAS stage only2.86[1.82-4.55]81 African American female cases; 261 African American female controls; 10 European ancestry female cases; 35 European ancestry female controls; 3 female cases; 22 female controlsNOPOP(25)European(45)African American(342)ALL(412)NOPOP(25)AFR(342)EUR(45)ALL(412)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumatic
1870683199rs2432835TCrs2432835228690350.0000153NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
2016740825rs4491792TCrs4491792237265114.00E-06Whole cohort; EANANAup to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controlsAfrican American(3392)European(1846)ALL(5238)AFR(3392)EUR(1846)ALL(5238)Post-traumatic stress disorder (asjusted for relatedness)HPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., Extramural
2057610059rs151358CArs151358228690350.000043NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
2057614002rs151361AGrs151361228690350.0000901NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.G
2133826744rs10854359CTrs10854359228690350.0000514NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.C
2133832194rs1041823TCrs1041823228690350.000051NANANA295 European ancestry cases; 196 European ancestry controlsEuropean(491)ALL(491)EUR(491)ALL(491)post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumaticNAResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.T
2233864817rs2413187AGrs2413187240801873.71E-06GWAS stage only2.78[1.84-4.19]81 African American female cases; 261 African American female controls; 10 European ancestry female cases; 35 European ancestry female controls; 3 female cases; 22 female controlsNOPOP(25)European(45)African American(342)ALL(412)NOPOP(25)AFR(342)EUR(45)ALL(412)Post-traumatic stress disorderHPOID:0100851Abnormal emotion/affect behaviorDOID:2055post-traumatic stress disorderNANAEFOID:0001358post-traumatic stress disorderStress disorder, post-traumatic
Mapped by lexical matching(Total Items:0)
(Waiting for update.)
Mapped by homologous gene(Total Items:0)
(Waiting for update.)
Chemical(Total Drugs:13)
CUI ChemicalName ChemicalID CasRN DiseaseName DiseaseID DirectEvidence PubMedIDs
C0038436alprazolamD00052528981-97-7stress disorders, post-traumaticMESH:D013313therapeutic2335496
C0038436carbamazepineD002220298-46-4stress disorders, post-traumaticMESH:D013313therapeutic12752037
C0038436citalopramD01528359729-33-8stress disorders, post-traumaticMESH:D013313therapeutic21112465
C0038436fluoxetineD00547354910-89-3stress disorders, post-traumaticMESH:D013313therapeutic11121880
C0038436fluvoxamineD01666654739-18-3stress disorders, post-traumaticMESH:D013313therapeutic11534878
C0038436imipramineD00709950-49-7stress disorders, post-traumaticMESH:D013313therapeutic7908665
C0038436lorazepamD008140846-49-1stress disorders, post-traumaticMESH:D013313therapeutic9160580
C0038436metoprololD00879037350-58-6stress disorders, post-traumaticMESH:D013313marker/mechanism12954926
C0038436olanzapineC076029132539-06-1stress disorders, post-traumaticMESH:D013313therapeutic12752037
C0038436prazosinD01122419216-56-9stress disorders, post-traumaticMESH:D013313therapeutic18519538
C0038436sulpirideD01346915676-16-1stress disorders, post-traumaticMESH:D013313therapeutic12752037
C0038436valproic acidD01463599-66-1stress disorders, post-traumaticMESH:D013313therapeutic15643110
C0038436zidovudineD01521530516-87-1stress disorders, post-traumaticMESH:D013313marker/mechanism12859331
FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)
FDA labeling changes(Total Drugs:0)
(Waiting for update.)