post-traumatic stress disorder |
Disease ID | 656 |
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Disease | post-traumatic stress disorder |
Manually Symptom | (Waiting for update.) |
Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:13) C0003467 | anxiety | 9 C0231303 | distress | 8 C0037317 | sleep disturbance | 5 C0003469 | anxiety disorders | 3 C0871189 | psychotic symptoms | 2 C0004936 | mental disorders | 2 C0002766 | analgesia | 1 C0037317 | sleep disturbances | 1 C0851578 | sleep disorders | 1 C0236720 | flashbacks | 1 C0002020 | alexithymia | 1 C0422833 | ent symptoms | 1 C0917801 | insomnia | 1 |
Manually Genotype(Total Text Mining Genotypes:0) |
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(Waiting for update.) |
All Snps(Total Genotypes:32) | |||||||||||||
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snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
rs10055255 | 24075295 | 1392 | CRH | umls:C0038436 | BeFree | To determine if single nucleotide polymorphisms of the corticotrophin-releasing hormone binding protein (CRHBP, rs10055255) and CRH receptor type 1 (CRHR1, rs1876831) were associated with posttraumatic stress disorder (PTSD) and depressive symptoms following medical-surgical intensive care unit (ICU) hospitalization. | 0.000814326 | 2013 | CRHBP | 5 | 76968168 | A | T |
rs10055255 | 24075295 | 1394 | CRHR1 | umls:C0038436 | BeFree | To determine if single nucleotide polymorphisms of the corticotrophin-releasing hormone binding protein (CRHBP, rs10055255) and CRH receptor type 1 (CRHR1, rs1876831) were associated with posttraumatic stress disorder (PTSD) and depressive symptoms following medical-surgical intensive care unit (ICU) hospitalization. | 0.001357209 | 2013 | CRHBP | 5 | 76968168 | A | T |
rs1033962 | 25456346 | 56952 | PRTFDC1 | umls:C0038436 | GWASCAT | Genomic predictors of combat stress vulnerability and resilience in U.S. Marines: A genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene. | 0.120271442 | 2014 | PRTFDC1 | 10 | 24927877 | C | T |
rs1360780 | 24959896 | 2908 | NR3C1 | umls:C0038436 | BeFree | As FKBP5 single-nucleotide polymorphism rs1360780 has a putative functional role in the regulation of FKBP5 expression and GR sensitivity, we hypothesized that this polymorphism influences PTSD treatment success. | 0.085157396 | 2014 | FKBP5;LOC105375032 | 6 | 35639794 | T | C |
rs1360780 | 25331639 | 2289 | FKBP5 | umls:C0038436 | BeFree | The common single nucleotide polymorphism (SNP) rs1360780 (C/T) of the FK506 Binding Protein 5 (FKBP5) gene has been reported to be associated with an altered response of the hypothalamic-pituitary-adrenal (HPA) axis and the development of stress-related psychiatric disorders such as posttraumatic stress disorder (PTSD). | 0.007252986 | 2014 | FKBP5;LOC105375032 | 6 | 35639794 | T | C |
rs1387923 | 17570738 | 4915 | NTRK2 | umls:C0038436 | BeFree | Using q-value analysis for multiplicity correction, we found significant interactions between lithium response and SNPs (rs1387923 and rs1565445) in the gene encoding neurotrophic tyrosine kinase receptor type 2 (NTRK2) and suicidal ideation, and between SNP rs2064721 in the gene encoding inositol polyphosphate-1-phosphatase (INPP1) and post-traumatic stress disorder. | 0.080271442 | 2007 | NTRK2 | 9 | 85025721 | A | G |
rs1387923 | 17570738 | 3628 | INPP1 | umls:C0038436 | BeFree | Using q-value analysis for multiplicity correction, we found significant interactions between lithium response and SNPs (rs1387923 and rs1565445) in the gene encoding neurotrophic tyrosine kinase receptor type 2 (NTRK2) and suicidal ideation, and between SNP rs2064721 in the gene encoding inositol polyphosphate-1-phosphatase (INPP1) and post-traumatic stress disorder. | 0.000271442 | 2007 | NTRK2 | 9 | 85025721 | A | G |
rs1565445 | 17570738 | 3628 | INPP1 | umls:C0038436 | BeFree | Using q-value analysis for multiplicity correction, we found significant interactions between lithium response and SNPs (rs1387923 and rs1565445) in the gene encoding neurotrophic tyrosine kinase receptor type 2 (NTRK2) and suicidal ideation, and between SNP rs2064721 in the gene encoding inositol polyphosphate-1-phosphatase (INPP1) and post-traumatic stress disorder. | 0.000271442 | 2007 | NTRK2 | 9 | 85002156 | G | A |
rs1565445 | 17570738 | 4915 | NTRK2 | umls:C0038436 | BeFree | Using q-value analysis for multiplicity correction, we found significant interactions between lithium response and SNPs (rs1387923 and rs1565445) in the gene encoding neurotrophic tyrosine kinase receptor type 2 (NTRK2) and suicidal ideation, and between SNP rs2064721 in the gene encoding inositol polyphosphate-1-phosphatase (INPP1) and post-traumatic stress disorder. | 0.080271442 | 2007 | NTRK2 | 9 | 85002156 | G | A |
rs16904179 | 23726511 | 51571 | FAM49B | umls:C0038436 | GWASCAT | Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder. | 0.12 | 2013 | FAM49B | 8 | 129946705 | G | A |
rs16965628 | 21545724 | 6532 | SLC6A4 | umls:C0038436 | BeFree | The SLC6A4 SNP rs16965628 and 5-HTTLPR are associated with a bias in neural responses to traumatic reminders and cognitive control of emotions in patients with PTSD. | 0.016525617 | 2011 | SLC6A4 | 17 | 30228407 | G | C |
rs1876831 | 24075295 | 1394 | CRHR1 | umls:C0038436 | BeFree | To determine if single nucleotide polymorphisms of the corticotrophin-releasing hormone binding protein (CRHBP, rs10055255) and CRH receptor type 1 (CRHR1, rs1876831) were associated with posttraumatic stress disorder (PTSD) and depressive symptoms following medical-surgical intensive care unit (ICU) hospitalization. | 0.001357209 | 2013 | CRHR1;MGC57346-CRHR1;LOC105371801 | 17 | 45830379 | C | T |
rs1876831 | 24075295 | 1392 | CRH | umls:C0038436 | BeFree | To determine if single nucleotide polymorphisms of the corticotrophin-releasing hormone binding protein (CRHBP, rs10055255) and CRH receptor type 1 (CRHR1, rs1876831) were associated with posttraumatic stress disorder (PTSD) and depressive symptoms following medical-surgical intensive care unit (ICU) hospitalization. | 0.000814326 | 2013 | CRHR1;MGC57346-CRHR1;LOC105371801 | 17 | 45830379 | C | T |
rs2064721 | 17570738 | 4915 | NTRK2 | umls:C0038436 | BeFree | Using q-value analysis for multiplicity correction, we found significant interactions between lithium response and SNPs (rs1387923 and rs1565445) in the gene encoding neurotrophic tyrosine kinase receptor type 2 (NTRK2) and suicidal ideation, and between SNP rs2064721 in the gene encoding inositol polyphosphate-1-phosphatase (INPP1) and post-traumatic stress disorder. | 0.080271442 | 2007 | AGPAT4 | 6 | 161187984 | T | C |
rs2064721 | 17570738 | 3628 | INPP1 | umls:C0038436 | BeFree | Using q-value analysis for multiplicity correction, we found significant interactions between lithium response and SNPs (rs1387923 and rs1565445) in the gene encoding neurotrophic tyrosine kinase receptor type 2 (NTRK2) and suicidal ideation, and between SNP rs2064721 in the gene encoding inositol polyphosphate-1-phosphatase (INPP1) and post-traumatic stress disorder. | 0.000271442 | 2007 | AGPAT4 | 6 | 161187984 | T | C |
rs2267735 | 23505260 | 117 | ADCYAP1R1 | umls:C0038436 | BeFree | (2011); Nature 470:492-497] demonstrated that a variant, rs2267735, in the gene encoding PAC1 (ADCYAP1R1) is associated with post-traumatic stress disorder (PTSD) in a primarily African-American cohort of highly traumatized females. | 0.001628651 | 2013 | ADCYAP1R1 | 7 | 31095890 | C | G |
rs25531 | 21818827 | 6532 | SLC6A4 | umls:C0038436 | BeFree | The relationship between combat-related posttraumatic stress disorder and the 5-HTTLPR/rs25531 polymorphism. | 0.016525617 | 2011 | SLC6A4;LOC105371720 | 17 | 30237328 | T | C |
rs263232 | 24677629 | 114 | ADCY8 | umls:C0038436 | GWASCAT | A genome-wide association study of clinical symptoms of dissociation in a trauma-exposed sample. | 0.12 | 2014 | ADCY8 | 8 | 130795923 | C | A |
rs3100127 | 25456346 | 59352 | LGR6 | umls:C0038436 | GWASCAT | Genomic predictors of combat stress vulnerability and resilience in U.S. Marines: A genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene. | 0.12 | 2014 | NA | 1 | 202191842 | C | A |
rs386602118 | 16649215 | 627 | BDNF | umls:C0038436 | BeFree | This variant and two previously reported BDNF SNPs (C270T and Val66Met) were genotyped in 295 patients with AD, 108 with AFDs, 96 with posttraumatic stress disorder (PTSD), 84 with schizophrenia, 327 with alcohol and/or drug dependence, and 250 normal control subjects. | 0.002714419 | 2006 | NA | NA | NA | NA | NA |
rs386602118 | 23312562 | 627 | BDNF | umls:C0038436 | BeFree | The brain-derived neurotrophic factor Val66Met polymorphism predicts response to exposure therapy in posttraumatic stress disorder. | 0.002714419 | 2013 | NA | NA | NA | NA | NA |
rs386602118 | 21728904 | 627 | BDNF | umls:C0038436 | BeFree | The association between brain-derived neurotrophic factor Val66Met variants and psychotic symptoms in posttraumatic stress disorder. | 0.002714419 | 2012 | NA | NA | NA | NA | NA |
rs386602118 | 20955337 | 627 | BDNF | umls:C0038436 | BeFree | Variant brain-derived neurotrophic factor Val66Met endophenotypes: implications for posttraumatic stress disorder. | 0.002714419 | 2010 | NA | NA | NA | NA | NA |
rs386602118 | 21491204 | 627 | BDNF | umls:C0038436 | BeFree | The objective of the present study was to identify, in a case-control study, whether the brain-derived neurotrophic factor (BDNF) val66met polymorphism (rs6265), the dopamine transporter (DAT1) three prime untranslated region (3'UTR) variable number of tandem repeats (VNTR), and the serotonin transporter (5-HTTPRL) short/long variants are associated with the development of PTSD in a group of victims of urban violence. | 0.002714419 | 2011 | NA | NA | NA | NA | NA |
rs386602118 | 23103549 | 1813 | DRD2 | umls:C0038436 | BeFree | BDNF Val66Met and DRD2 Taq1A polymorphisms interact to influence PTSD symptom severity: a preliminary investigation in a South African population. | 0.007177041 | 2013 | NA | NA | NA | NA | NA |
rs4511180 | 25456346 | 148713 | PTPRVP | umls:C0038436 | GWASCAT | Genomic predictors of combat stress vulnerability and resilience in U.S. Marines: A genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene. | 0.12 | 2014 | PTPRVP | 1 | 202180311 | A | G |
rs4680 | 21783175 | 1312 | COMT | umls:C0038436 | BeFree | Catechol-O-methyltransferase Val158Met polymorphism moderates anterior cingulate volume in posttraumatic stress disorder. | 0.001357209 | 2011 | COMT;MIR4761 | 22 | 19963748 | G | A |
rs4680 | 19944409 | 1312 | COMT | umls:C0038436 | BeFree | The risk of posttraumatic stress disorder after trauma depends on traumatic load and the catechol-o-methyltransferase Val(158)Met polymorphism. | 0.001357209 | 2010 | COMT;MIR4761 | 22 | 19963748 | G | A |
rs6265 | 21491204 | 627 | BDNF | umls:C0038436 | BeFree | The objective of the present study was to identify, in a case-control study, whether the brain-derived neurotrophic factor (BDNF) val66met polymorphism (rs6265), the dopamine transporter (DAT1) three prime untranslated region (3'UTR) variable number of tandem repeats (VNTR), and the serotonin transporter (5-HTTPRL) short/long variants are associated with the development of PTSD in a group of victims of urban violence. | 0.002714419 | 2011 | BDNF;BDNF-AS | 11 | 27658369 | C | T |
rs6277 | 18833581 | 1813 | DRD2 | umls:C0038436 | GAD | [The DRD2 gene 957C>T polymorphism is associated with posttraumatic stress disorder in war veterans.] | 0.007177041 | 2009 | DRD2 | 11 | 113412737 | G | A |
rs6812849 | 23726511 | 7092 | TLL1 | umls:C0038436 | GWASCAT | This study identified TLL1 as a new susceptibility gene for PTSD. | 0.12 | 2013 | TLL1 | 4 | 165951384 | C | A |
rs7866350 | 26114229 | 55357 | TBC1D2 | umls:C0038436 | GWASCAT | Genome-wide association study of posttraumatic stress disorder in a cohort of Iraq-Afghanistan era veterans. | 0.12 | 2015 | TBC1D2 | 9 | 98221544 | C | G,T |
GWASdb Annotation(Total Genotypes:0) | |
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(Waiting for update.) |
GWASdb Snp Trait(Total Genotypes:164) | |||||||||||||||||||||||||||||
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CHR | POS | SNPID | REF | ALT | ORI_SNPID | PMID | P_VALUE | P_VALUE_TEXT | OR/BETA | CI95_TEXT | GWAS_INITIAL_SAMPLE_SIZE | SUB_POPULATION | SUPER_POPULATION | GWAS_TRAIT | HPO_ID | HPO_TERM | DO_ID | DO_TERM | MESH_ID | MESH_TERM | EFO_ID | EFO_TERM | DOLITE_TERM | RISK_ALLELE | PUBLICATION_TYPE | AA | GENE_SYMBOL | TYPE | REFGENE |
1 | 12194451 | rs1148472 | T | C | rs1148472 | 22869035 | 0.0000922 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
1 | 40222660 | rs7553968 | G | C | rs7553968 | 22869035 | 0.0000882 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
1 | 74898117 | rs477159 | G | A | rs477159 | 22869035 | 0.0000338 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | A |
1 | 74899573 | rs792884 | T | G | rs792884 | 22869035 | 0.0000157 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
1 | 74900897 | rs643371 | A | C | rs643371 | 22869035 | 0.0000987 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
1 | 74907316 | rs1325604 | G | A | rs1325604 | 22869035 | 0.000085 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
1 | 154713341 | rs1506985 | T | C | rs1506985 | 22869035 | 0.0000466 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | A |
1 | 154714006 | rs4999127 | G | A | rs4999127 | 22869035 | 0.0000206 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | A |
1 | 232444455 | rs9725031 | C | T | rs9725031 | 24677629 | 8.00E-06 | NA | 1.13 | [0.64-1.62] unit increase | 484 European ancestry trauma-exposed individuals | European(484) | ALL(484) | EUR(484) | ALL(484) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
1 | 238573691 | rs1021356 | A | G | rs1021356 | 22869035 | 0.0000049 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
1 | 238574814 | rs6662339 | C | T | rs6662339 | 22869035 | 0.0000423 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
1 | 238575717 | rs6689284 | G | A | rs6689284 | 22869035 | 0.0000315 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | A |
1 | 238575867 | rs6665978 | C | T | rs6665978 | 22869035 | 0.0000315 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
1 | 238576614 | rs12118091 | T | G | rs12118091 | 22869035 | 0.0000049 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
1 | 238576715 | rs113508478 | C | T | rs113508478 | 22869035 | 0.0000074 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
1 | 238576715 | rs113508478 | C | T | rs147773561 | 22869035 | 0.00000735 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
1 | 242603059 | rs2055536 | A | G | rs2055536 | 22869035 | 0.0000996 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
1 | 242603249 | rs2810030 | G | A | rs2810030 | 22869035 | 0.0000971 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
1 | 244015993 | rs4430311 | C | T | rs4430311 | 23726511 | 6.00E-06 | Trauma exposed controls; EA | NA | NA | up to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controls | African American(3392) | European(1846) | ALL(5238) | AFR(3392) | EUR(1846) | ALL(5238) | Post-traumatic stress disorder (asjusted for relatedness) | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
2 | 5925857 | rs1560238 | C | T | rs1560238 | 22869035 | 0.0000174 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | A |
2 | 5926156 | rs16864200 | C | T | rs16864200 | 22869035 | 0.0000169 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
2 | 5928093 | rs16864209 | T | C | rs16864209 | 22869035 | 0.0000169 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
2 | 27743423 | rs11681351 | G | A | rs11681351 | 22869035 | 0.000077 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
2 | 27746832 | rs8179252 | A | C | rs8179252 | 22869035 | 0.000077 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | A |
2 | 27794233 | rs10205364 | C | T | rs10205364 | 22869035 | 0.0000912 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
2 | 27801403 | rs1919125 | C | G | rs1919125 | 22869035 | 0.000093 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
2 | 27801418 | rs1919126 | C | A | rs1919126 | 22869035 | 0.0000902 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | A |
2 | 27807624 | rs13026621 | G | A | rs13026621 | 22869035 | 0.0000902 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | A |
2 | 27855239 | rs4666005 | A | G | rs4666005 | 22869035 | 0.0000683 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
2 | 27857517 | rs1528402 | G | A | rs1528402 | 22869035 | 0.0000298 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | A |
2 | 74463566 | rs13006863 | C | T | rs13006863 | 23726511 | 3.00E-06 | Whole cohort; AA | NA | NA | up to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controls | African American(3392) | European(1846) | ALL(5238) | AFR(3392) | EUR(1846) | ALL(5238) | Post-traumatic stress disorder (asjusted for relatedness) | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
2 | 188814444 | rs10170218 | A | C | rs10170218 | 24080187 | 5.10E-08 | GWAS stage only | 2.89 | [1.97-4.23] | 81 African American female cases; 261 African American female controls; 10 European ancestry female cases; 35 European ancestry female controls; 3 female cases; 22 female controls | NOPOP(25) | European(45) | African American(342) | ALL(412) | NOPOP(25) | AFR(342) | EUR(45) | ALL(412) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic |
2 | 202122995 | rs3769823 | A | G | rs3769823 | 22869035 | 0.0000488 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
2 | 202151163 | rs3769818 | A | G | rs3769818 | 22869035 | 0.0000334 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
2 | 202153225 | rs700635 | C | A | rs700635 | 22869035 | 0.0000334 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | A |
2 | 202153684 | rs6714430 | C | T | rs6714430 | 22869035 | 0.0000334 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
3 | 20083881 | rs1915919 | C | T | rs1915919 | 24677629 | 8.00E-06 | NA | 0.74 | [0.43-1.05] unit increase | 484 European ancestry trauma-exposed individuals | European(484) | ALL(484) | EUR(484) | ALL(484) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
3 | 64617070 | rs6445420 | C | T | rs6445420 | 22869035 | 0.0000967 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
3 | 107640533 | rs13086279 | G | A | rs13086279 | 22869035 | 0.0000929 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
3 | 178782021 | rs4955793 | C | T | rs4955793 | 23726511 | 2.00E-06 | Whole cohort; AA | NA | NA | up to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controls | African American(3392) | European(1846) | ALL(5238) | AFR(3392) | EUR(1846) | ALL(5238) | Post-traumatic stress disorder (asjusted for relatedness) | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
4 | 58080251 | rs6850123 | C | T | rs6850123 | 22869035 | 0.0000749 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
4 | 58081590 | rs1860623 | A | G | rs1860623 | 22869035 | 0.000086 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
4 | 65392212 | rs1425392 | T | C | rs1425392 | 23726511 | 7.00E-06 | Trauma exposed controls; EA | NA | NA | up to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controls | African American(3392) | European(1846) | ALL(5238) | AFR(3392) | EUR(1846) | ALL(5238) | Post-traumatic stress disorder (asjusted for relatedness) | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
4 | 122445005 | rs7673847 | T | C | rs7673847 | 22869035 | 0.0000621 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
4 | 122446695 | rs200748952 | G | T | rs142186713 | 22869035 | 0.0000966 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
4 | 122446695 | rs35950299 | G | GT | rs142186713 | 22869035 | 0.0000966 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
4 | 122446695 | rs397878254 | G | GT | rs142186713 | 22869035 | 0.0000966 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
4 | 166865585 | rs7691872 | G | T | rs7691872 | 23726511 | 1.22E-07 | Whole cohort; EA | NA | NA | 300 European ancestry cases; up to 1,538 European ancestry controls; 444 African American cases; up to 2,936 African American controls | African American(3380) | European(1838) | ALL(5218) | AFR(3380) | EUR(1838) | ALL(5218) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
4 | 166872536 | rs6812849 | C | A | rs6812849 | 23726511 | 1.00E-06 | Trauma Exposed controls; EA | NA | NA | 300 European ancestry cases; up to 1,538 European ancestry controls; 444 African American cases; up to 2,936 African American controls | African American(3380) | European(1838) | ALL(5218) | AFR(3380) | EUR(1838) | ALL(5218) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
4 | 166872536 | rs6812849 | C | A | rs6812849 | 23726511 | 1.00E-07 | Whole cohort; EA | NA | NA | up to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controls | African American(3392) | European(1846) | ALL(5238) | AFR(3392) | EUR(1846) | ALL(5238) | Post-traumatic stress disorder (asjusted for relatedness) | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
4 | 166872536 | rs6812849 | C | A | rs6812849 | 23726511 | 3.00E-09 | Whole cohort; EA | NA | NA | 300 European ancestry cases; up to 1,538 European ancestry controls; 444 African American cases; up to 2,936 African American controls | African American(3380) | European(1838) | ALL(5218) | AFR(3380) | EUR(1838) | ALL(5218) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
4 | 166872536 | rs6812849 | C | A | rs6812849 | 23726511 | 5.00E-07 | Trauma exposed controls; EA | NA | NA | up to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controls | African American(3392) | European(1846) | ALL(5238) | AFR(3392) | EUR(1846) | ALL(5238) | Post-traumatic stress disorder (asjusted for relatedness) | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
4 | 187719659 | rs7698529 | G | A | rs7698529 | 22869035 | 0.0000795 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | A |
4 | 187722479 | rs11132409 | C | T | rs11132409 | 22869035 | 0.0000989 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
5 | 17761225 | rs11959046 | G | A | rs11959046 | 22869035 | 0.0000816 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
5 | 146610829 | rs31031 | T | C | rs31031 | 22869035 | 0.0000168 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
5 | 171474120 | rs6892217 | C | T | rs6892217 | 22869035 | 0.0000781 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
5 | 178897590 | rs4701170 | G | A | rs4701170 | 24080187 | 7.92E-06 | GWAS stage only | 2.41 | [1.66-3.51] | 81 African American female cases; 261 African American female controls; 10 European ancestry female cases; 35 European ancestry female controls; 3 female cases; 22 female controls | NOPOP(25) | European(45) | African American(342) | ALL(412) | NOPOP(25) | AFR(342) | EUR(45) | ALL(412) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic |
6 | 25219582 | rs77006546 | T | C | rs77006546 | 24677629 | 9.60E-06 | NA | 1.7 | [0.96-1.7] unit increase | 484 European ancestry trauma-exposed individuals | European(484) | ALL(484) | EUR(484) | ALL(484) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
6 | 29809382 | rs1611133 | C | T | rs1611133 | 24080187 | 1.18E-06 | GWAS stage only | 3.56 | [2.04-6.22] | 81 African American female cases; 261 African American female controls; 10 European ancestry female cases; 35 European ancestry female controls; 3 female cases; 22 female controls | NOPOP(25) | European(45) | African American(342) | ALL(412) | NOPOP(25) | AFR(342) | EUR(45) | ALL(412) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic |
6 | 31045554 | rs9378152 | C | G | rs9378152 | 22869035 | 0.0000492 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
6 | 31049655 | rs9380215 | G | A | rs9380215 | 22869035 | 0.0000374 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
6 | 31055018 | rs12527394 | G | A | rs12527394 | 22869035 | 0.0000376 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
6 | 31058178 | rs4947296 | T | C | rs4947296 | 22869035 | 0.0000374 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
6 | 31070522 | rs9394037 | G | A | rs9394037 | 22869035 | 0.0000241 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
6 | 31074128 | rs4947302 | C | T | rs4947302 | 22869035 | 0.0000526 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
6 | 31074148 | rs4947246 | G | T | rs4947246 | 22869035 | 0.0000511 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
6 | 31077405 | rs9391709 | G | C | rs9391709 | 22869035 | 0.0000511 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
6 | 31079264 | rs2233984 | C | T | rs2233984 | 22869035 | 0.0000511 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
6 | 33917711 | rs10947469 | G | A | rs10947469 | 22869035 | 0.0000889 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
6 | 43900443 | rs833621 | T | C | rs833621 | 22869035 | 0.0000206 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | A |
6 | 82933309 | rs9361904 | C | T | rs9361904 | 22869035 | 0.0000795 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
6 | 138484125 | rs72986828 | T | G | rs72986828 | 22869035 | 0.0000056 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
6 | 138484764 | rs6907714 | A | G | rs6907714 | 22869035 | 0.0000203 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
6 | 156320573 | rs4869880 | C | T | rs4869880 | 22869035 | 0.0000933 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T,C |
7 | 3179991 | rs7779245 | T | C | rs7779245 | 22869035 | 0.0000978 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
7 | 3180657 | rs6964682 | C | T | rs6964682 | 22869035 | 0.0000802 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
7 | 16556076 | rs57025232 | T | C | rs57025232 | 22869035 | 0.0000587 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
7 | 52006415 | rs406001 | T | C | rs406001 | 23726511 | 2.00E-08 | Whole cohort; EA | NA | NA | up to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controls | African American(3392) | European(1846) | ALL(5238) | AFR(3392) | EUR(1846) | ALL(5238) | Post-traumatic stress disorder (asjusted for relatedness) | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
7 | 52006415 | rs406001 | T | C | rs406001 | 23726511 | 2.77E-04 | Whole cohort; EA | NA | NA | 300 European ancestry cases; up to 1,538 European ancestry controls; 444 African American cases; up to 2,936 African American controls | African American(3380) | European(1838) | ALL(5218) | AFR(3380) | EUR(1838) | ALL(5218) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
7 | 52006415 | rs406001 | T | C | rs406001 | 23726511 | 3.00E-08 | Trauma exposed controls; EA | NA | NA | up to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controls | African American(3392) | European(1846) | ALL(5238) | AFR(3392) | EUR(1846) | ALL(5238) | Post-traumatic stress disorder (asjusted for relatedness) | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
7 | 52008734 | rs450378 | C | T | rs450378 | 23726511 | 2.03E-04 | Whole cohort; EA | NA | NA | 300 European ancestry cases; up to 1,538 European ancestry controls; 444 African American cases; up to 2,936 African American controls | African American(3380) | European(1838) | ALL(5218) | AFR(3380) | EUR(1838) | ALL(5218) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
7 | 52008734 | rs450378 | C | T | rs450378 | 23726511 | 5.59E-04 | Trauma exposed controls; EA | NA | NA | 300 European ancestry cases; up to 1,538 European ancestry controls; 444 African American cases; up to 2,936 African American controls | African American(3380) | European(1838) | ALL(5218) | AFR(3380) | EUR(1838) | ALL(5218) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
7 | 77985864 | rs4730234 | T | C | rs4730234 | 22869035 | 0.0000725 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
7 | 77988279 | rs12670218 | C | T | rs12670218 | 22869035 | 0.0000877 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
7 | 82646210 | rs28156 | T | C | rs28156 | 22869035 | 0.000044 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
7 | 112130009 | rs11767398 | A | C | rs11767398 | 24080187 | 5.95E-06 | GWAS stage only | 2.54 | [1.71-3.78] | 81 African American female cases; 261 African American female controls; 10 European ancestry female cases; 35 European ancestry female controls; 3 female cases; 22 female controls | NOPOP(25) | European(45) | African American(342) | ALL(412) | NOPOP(25) | AFR(342) | EUR(45) | ALL(412) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic |
7 | 154592866 | rs71534169 | T | G | rs71534169 | 24677629 | 4.00E-06 | NA | 1.63 | [0.94-2.32] unit increase | 484 European ancestry trauma-exposed individuals | European(484) | ALL(484) | EUR(484) | ALL(484) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
8 | 6715719 | rs2980946 | A | C | rs2980946 | 22869035 | 0.0000757 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
8 | 12808108 | rs62488971 | C | T | rs62488971 | 24677629 | 8.37E-06 | NA | 1.58 | [0.89-1.58] unit increase | 484 European ancestry trauma-exposed individuals | European(484) | ALL(484) | EUR(484) | ALL(484) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
8 | 12834600 | rs2460905 | G | A | rs2460905 | 24677629 | 5.00E-06 | NA | 1.38 | [0.79-1.97] unit increase | 484 European ancestry trauma-exposed individuals | European(484) | ALL(484) | EUR(484) | ALL(484) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
8 | 12866004 | rs2466273 | A | C | rs2466273 | 24677629 | 7.10E-06 | NA | 1.31 | [0.74-1.31] unit increase | 484 European ancestry trauma-exposed individuals | European(484) | ALL(484) | EUR(484) | ALL(484) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
8 | 27073268 | rs1446684 | A | C | rs1446684 | 22869035 | 0.0000821 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
8 | 31448469 | rs13258147 | G | A | rs13258147 | 22869035 | 0.0000878 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
8 | 41228458 | rs10958680 | C | T | rs10958680 | 22869035 | 0.0000981 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
8 | 41231950 | rs2883471 | C | T | rs2883471 | 22869035 | 0.0000236 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G,A |
8 | 82069207 | rs11988289 | A | C | rs11988289 | 22869035 | 0.0000286 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | A |
8 | 115578307 | rs7014900 | T | G | rs7014900 | 23726511 | 1.31E-04 | Whole cohort; AA | NA | NA | 300 European ancestry cases; up to 1,538 European ancestry controls; 444 African American cases; up to 2,936 African American controls | African American(3380) | European(1838) | ALL(5218) | AFR(3380) | EUR(1838) | ALL(5218) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
8 | 115578307 | rs7014900 | T | G | rs7014900 | 23726511 | 2.00E-06 | Whole cohort; AA | NA | NA | up to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controls | African American(3392) | European(1846) | ALL(5238) | AFR(3392) | EUR(1846) | ALL(5238) | Post-traumatic stress disorder (asjusted for relatedness) | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
8 | 115578307 | rs7014900 | T | G | rs7014900 | 23726511 | 3.90E-04 | Trauma exposed controls; AA | NA | NA | 300 European ancestry cases; up to 1,538 European ancestry controls; 444 African American cases; up to 2,936 African American controls | African American(3380) | European(1838) | ALL(5218) | AFR(3380) | EUR(1838) | ALL(5218) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
8 | 115578307 | rs7014900 | T | G | rs7014900 | 23726511 | 4.00E-06 | Trauma exposed controls; AA | NA | NA | up to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controls | African American(3392) | European(1846) | ALL(5238) | AFR(3392) | EUR(1846) | ALL(5238) | Post-traumatic stress disorder (asjusted for relatedness) | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
8 | 122948438 | rs12676697 | T | C | rs12676697 | 22869035 | 0.0000939 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
8 | 130958951 | rs16904179 | G | A | rs16904179 | 23726511 | 7.00E-07 | Whole cohort; AA | NA | NA | up to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controls | African American(3392) | European(1846) | ALL(5238) | AFR(3392) | EUR(1846) | ALL(5238) | Post-traumatic stress disorder (asjusted for relatedness) | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
8 | 131808169 | rs263232 | C | A | rs263232 | 24677629 | 6.00E-07 | NA | 1.43 | [0.88-1.98] unit increase | 484 European ancestry trauma-exposed individuals | European(484) | ALL(484) | EUR(484) | ALL(484) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
8 | 134270548 | rs2272651 | T | C | rs2272651 | 23726511 | 3.00E-06 | Whole cohort; EA | NA | NA | up to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controls | African American(3392) | European(1846) | ALL(5238) | AFR(3392) | EUR(1846) | ALL(5238) | Post-traumatic stress disorder (asjusted for relatedness) | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
8 | 134270548 | rs2272651 | T | C | rs2272651 | 23726511 | 5.36E-05 | Whole cohort; EA | NA | NA | 300 European ancestry cases; up to 1,538 European ancestry controls; 444 African American cases; up to 2,936 African American controls | African American(3380) | European(1838) | ALL(5218) | AFR(3380) | EUR(1838) | ALL(5218) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
8 | 144231514 | rs4977138 | A | G | rs4977138 | 22869035 | 0.0000697 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
8 | 144234489 | rs6420183 | C | T | rs6420183 | 22869035 | 0.0000414 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
9 | 2289519 | rs7861374 | C | A | rs7861374 | 22869035 | 0.0000708 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | A |
9 | 2299220 | rs10965506 | T | G | rs10965506 | 22869035 | 0.0000812 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
9 | 2300565 | rs13292475 | T | C | rs13292475 | 22869035 | 0.0000624 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
9 | 2301724 | rs13294267 | A | G | rs13294267 | 22869035 | 0.000044 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | A |
9 | 8709838 | rs16928304 | A | G | rs16928304 | 22869035 | 0.0000653 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
9 | 80997705 | rs2989585 | A | G | rs2989585 | 22869035 | 0.0000738 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
9 | 101253226 | rs2779551 | T | C | rs2779551 | 23726511 | 2.00E-06 | Whole cohort; EA | NA | NA | up to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controls | African American(3392) | European(1846) | ALL(5238) | AFR(3392) | EUR(1846) | ALL(5238) | Post-traumatic stress disorder (asjusted for relatedness) | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
9 | 111936128 | rs7858727 | C | A | rs7858727 | 22869035 | 0.0000185 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
9 | 111938125 | rs10119402 | G | T | rs10119402 | 22869035 | 0.0000132 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
9 | 111945049 | rs3750450 | T | G | rs3750450 | 22869035 | 0.0000897 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | A |
9 | 111958345 | rs6415807 | G | A | rs6415807 | 22869035 | 0.0000131 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | A |
10 | 57549296 | rs16907840 | C | T | rs16907840 | 23726511 | 8.00E-06 | Whole cohort; EA | NA | NA | up to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controls | African American(3392) | European(1846) | ALL(5238) | AFR(3392) | EUR(1846) | ALL(5238) | Post-traumatic stress disorder (asjusted for relatedness) | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
10 | 63678484 | rs77968426 | C | T | rs77968426 | 22869035 | 0.0000435 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
10 | 87608460 | rs7076096 | C | T | rs7076096 | 23726511 | 5.00E-06 | Trauma exposed controls; AA | NA | NA | up to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controls | African American(3392) | European(1846) | ALL(5238) | AFR(3392) | EUR(1846) | ALL(5238) | Post-traumatic stress disorder (asjusted for relatedness) | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
10 | 90985948 | rs2254747 | C | T | rs2254747 | 22869035 | 0.0000635 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
10 | 126073849 | rs870209 | C | T | rs870209 | 22869035 | 0.0000757 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
11 | 87949532 | rs682457 | T | C | rs682457 | 24677629 | 1.00E-06 | NA | 1.11 | [0.68-1.54] unit increase | 484 European ancestry trauma-exposed individuals | European(484) | ALL(484) | EUR(484) | ALL(484) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
11 | 99629201 | rs1219050 | G | A | rs1219050 | 22869035 | 0.000079 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
12 | 95119816 | rs7302717 | T | C | rs7302717 | 24080187 | 5.72E-06 | GWAS stage only | 2.44 | [1.67-3.57] | 81 African American female cases; 261 African American female controls; 10 European ancestry female cases; 35 European ancestry female controls; 3 female cases; 22 female controls | NOPOP(25) | European(45) | African American(342) | ALL(412) | NOPOP(25) | AFR(342) | EUR(45) | ALL(412) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic |
12 | 108167002 | rs57043169 | A | C,G | rs57043169 | 22869035 | 0.0000708 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | A |
13 | 114886976 | rs9525275 | T | C | rs9525275 | 22869035 | 0.0000199 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
14 | 24878485 | rs12897153 | G | A | rs12897153 | 22869035 | 0.0000784 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
14 | 49426842 | rs7158872 | G | T | rs7158872 | 23726511 | 2.00E-06 | Whole cohort; AA | NA | NA | up to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controls | African American(3392) | European(1846) | ALL(5238) | AFR(3392) | EUR(1846) | ALL(5238) | Post-traumatic stress disorder (asjusted for relatedness) | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
14 | 49426842 | rs7158872 | G | T | rs7158872 | 23726511 | 3.00E-06 | Trauma exposed controls; AA | NA | NA | up to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controls | African American(3392) | European(1846) | ALL(5238) | AFR(3392) | EUR(1846) | ALL(5238) | Post-traumatic stress disorder (asjusted for relatedness) | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
14 | 69789755 | rs3902951 | T | G | rs3902951 | 22869035 | 0.0000825 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | A |
15 | 55352945 | rs1528462 | C | T | rs1528462 | 22869035 | 0.000058 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
15 | 60801066 | rs16942660 | C | T | rs16942660 | 22869035 | 0.0009 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
15 | 61103590 | rs341366 | A | G | rs341366 | 22869035 | 0.0000373 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | A |
15 | 61109318 | rs2414681 | C | A | rs2414681 | 22869035 | 0.00005 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
15 | 61109873 | rs10519074 | C | A | rs10519074 | 22869035 | 0.0000154 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
15 | 61114104 | rs7169281 | T | C | rs7169281 | 22869035 | 0.0000295 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T,C |
15 | 61124838 | rs8041061 | G | T | rs8041061 | 22869035 | 0.00000016 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
15 | 61124953 | rs8042149 | T | G | rs8042149 | 22869035 | 2.49E-08 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
15 | 61126859 | rs4775301 | T | C | rs4775301 | 22869035 | 0.000000459 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
15 | 61130639 | rs8024133 | C | T | rs8024133 | 22869035 | 0.000000877 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
15 | 61131683 | rs11071561 | T | A | rs11071561 | 22869035 | 0.0000038 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | A |
15 | 61132845 | rs341401 | G | A | rs341401 | 22869035 | 0.000062 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
15 | 61433543 | rs11071587 | G | A | rs11071587 | 22869035 | 0.00011 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
15 | 61433578 | rs11071588 | T | G | rs11071588 | 22869035 | 0.0000677 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
15 | 82193846 | rs77963519 | G | A | rs77963519 | 24677629 | 4.00E-06 | NA | 1.56 | [0.91-2.21] unit increase | 484 European ancestry trauma-exposed individuals | European(484) | ALL(484) | EUR(484) | ALL(484) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
17 | 258914 | rs9895447 | G | A | rs9895447 | 22869035 | 0.0000112 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
17 | 259248 | rs71355256 | C | T | rs71355256 | 22869035 | 0.00000428 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
17 | 266655 | rs67288608 | G | C | rs67288608 | 22869035 | 0.0000116 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
17 | 273298 | rs6565727 | G | A | rs6565727 | 22869035 | 0.0000132 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
17 | 8905016 | rs7219148 | T | G | rs7219148 | 22869035 | 0.0000506 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
17 | 26686445 | rs17802736 | A | G | rs17802736 | 22869035 | 0.0000968 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | A |
17 | 31659032 | rs76604546 | T | A | rs76604546 | 22869035 | 0.0000718 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
17 | 64447165 | rs7207499 | G | A | rs7207499 | 23726511 | 5.00E-06 | Whole cohort; AA | NA | NA | up to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controls | African American(3392) | European(1846) | ALL(5238) | AFR(3392) | EUR(1846) | ALL(5238) | Post-traumatic stress disorder (asjusted for relatedness) | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
18 | 36040352 | rs10502692 | C | T | rs10502692 | 24080187 | 4.46E-06 | GWAS stage only | 2.86 | [1.82-4.55] | 81 African American female cases; 261 African American female controls; 10 European ancestry female cases; 35 European ancestry female controls; 3 female cases; 22 female controls | NOPOP(25) | European(45) | African American(342) | ALL(412) | NOPOP(25) | AFR(342) | EUR(45) | ALL(412) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic |
18 | 70683199 | rs2432835 | T | C | rs2432835 | 22869035 | 0.0000153 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
20 | 16740825 | rs4491792 | T | C | rs4491792 | 23726511 | 4.00E-06 | Whole cohort; EA | NA | NA | up to 308 European ancestry cases; up to 1,538 European ancestry controls; up to 456 African American cases; up to 2,936 African American controls | African American(3392) | European(1846) | ALL(5238) | AFR(3392) | EUR(1846) | ALL(5238) | Post-traumatic stress disorder (asjusted for relatedness) | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural |
20 | 57610059 | rs151358 | C | A | rs151358 | 22869035 | 0.000043 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
20 | 57614002 | rs151361 | A | G | rs151361 | 22869035 | 0.0000901 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | G |
21 | 33826744 | rs10854359 | C | T | rs10854359 | 22869035 | 0.0000514 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | C |
21 | 33832194 | rs1041823 | T | C | rs1041823 | 22869035 | 0.000051 | NA | NA | NA | 295 European ancestry cases; 196 European ancestry controls | European(491) | ALL(491) | EUR(491) | ALL(491) | post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic | NA | Research Support, N.I.H., Extramural | Research Support, U.S. Gov't, Non-P.H.S. | T |
22 | 33864817 | rs2413187 | A | G | rs2413187 | 24080187 | 3.71E-06 | GWAS stage only | 2.78 | [1.84-4.19] | 81 African American female cases; 261 African American female controls; 10 European ancestry female cases; 35 European ancestry female controls; 3 female cases; 22 female controls | NOPOP(25) | European(45) | African American(342) | ALL(412) | NOPOP(25) | AFR(342) | EUR(45) | ALL(412) | Post-traumatic stress disorder | HPOID:0100851 | Abnormal emotion/affect behavior | DOID:2055 | post-traumatic stress disorder | NA | NA | EFOID:0001358 | post-traumatic stress disorder | Stress disorder, post-traumatic |
Mapped by lexical matching(Total Items:0) |
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(Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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(Waiting for update.) |
Chemical(Total Drugs:13) | |||||||||
---|---|---|---|---|---|---|---|---|---|
CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
C0038436 | alprazolam | D000525 | 28981-97-7 | stress disorders, post-traumatic | MESH:D013313 | therapeutic | 2335496 | ||
C0038436 | carbamazepine | D002220 | 298-46-4 | stress disorders, post-traumatic | MESH:D013313 | therapeutic | 12752037 | ||
C0038436 | citalopram | D015283 | 59729-33-8 | stress disorders, post-traumatic | MESH:D013313 | therapeutic | 21112465 | ||
C0038436 | fluoxetine | D005473 | 54910-89-3 | stress disorders, post-traumatic | MESH:D013313 | therapeutic | 11121880 | ||
C0038436 | fluvoxamine | D016666 | 54739-18-3 | stress disorders, post-traumatic | MESH:D013313 | therapeutic | 11534878 | ||
C0038436 | imipramine | D007099 | 50-49-7 | stress disorders, post-traumatic | MESH:D013313 | therapeutic | 7908665 | ||
C0038436 | lorazepam | D008140 | 846-49-1 | stress disorders, post-traumatic | MESH:D013313 | therapeutic | 9160580 | ||
C0038436 | metoprolol | D008790 | 37350-58-6 | stress disorders, post-traumatic | MESH:D013313 | marker/mechanism | 12954926 | ||
C0038436 | olanzapine | C076029 | 132539-06-1 | stress disorders, post-traumatic | MESH:D013313 | therapeutic | 12752037 | ||
C0038436 | prazosin | D011224 | 19216-56-9 | stress disorders, post-traumatic | MESH:D013313 | therapeutic | 18519538 | ||
C0038436 | sulpiride | D013469 | 15676-16-1 | stress disorders, post-traumatic | MESH:D013313 | therapeutic | 12752037 | ||
C0038436 | valproic acid | D014635 | 99-66-1 | stress disorders, post-traumatic | MESH:D013313 | therapeutic | 15643110 | ||
C0038436 | zidovudine | D015215 | 30516-87-1 | stress disorders, post-traumatic | MESH:D013313 | marker/mechanism | 12859331 |
FDA approved drug and dosage information(Total Drugs:0) | |
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(Waiting for update.) |
FDA labeling changes(Total Drugs:0) | |
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(Waiting for update.) |