PedAM

Pediatric Disease Annotations & Medicines


	pneumococcal infections

Disease ID	1296
Disease	pneumococcal infections
Definition	Infections with bacteria of the species STREPTOCOCCUS PNEUMONIAE.
Synonym	infect pneumococcal infect strep pneumoniae infection, pneumococcal infection, streptococcus pneumoniae infections, pneumococcal infections, streptococcus pneumoniae pneumococcal disease pneumococcal infect pneumococcal infection pneumococcal infection, nos pneumococcal infections [disease/finding] pneumococcal infectious disease pneumococcal infectious disease (disorder) pneumococcal infectious disease, nos pneumoniae infection, streptococcus pneumoniae infections, streptococcus strep pneumoniae infect streptococcus pneumoniae infection streptococcus pneumoniae infections
DOID	DOID:9805
UMLS	C0032269
MeSH	D011008
SNOMED-CT	SNOMEDCT_US_2016_09_01:16814004
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:43) C0032285 \| pneumonia \| 11 C0021400 \| influenza \| 9 C0025289 \| meningitis \| 7 C0032285 \| pneumoniae \| 6 C0004096 \| asthma \| 3 C0002895 \| sickle cell disease \| 3 C0011847 \| diabetes \| 3 C0034150 \| purpura \| 2 C0010674 \| cystic fibrosis \| 2 C0024117 \| chronic obstructive pulmonary disease \| 2 C0014118 \| endocarditis \| 2 C0019061 \| haemolytic uraemic syndrome \| 2 C0017658 \| glomerulonephritis \| 1 C0012624 \| spondylodiscitis \| 1 C0600260 \| obstructive pulmonary disease \| 1 C0002895 \| sickle cell anaemia \| 1 C0042384 \| vasculitis \| 1 C0008780 \| primary ciliary dyskinesia \| 1 C0024115 \| lung diseases \| 1 C0026764 \| multiple myeloma \| 1 C0024115 \| pulmonary disease \| 1 C0013384 \| dyskinesia \| 1 C0019061 \| hemolytic uremic syndrome \| 1 C0027051 \| myocardial infarct \| 1 C0002895 \| sickle-cell disease \| 1 C0004936 \| mental disorders \| 1 C0032285 \| pneumonias \| 1 C0155862 \| pneumococcal pneumonia \| 1 C0026764 \| myeloma \| 1 C0004623 \| bacterial infection \| 1 C0024115 \| lung disease \| 1 C0022658 \| kidney disease \| 1 C0085650 \| purpura fulminans \| 1 C0004623 \| bacterial infections \| 1 C0155626 \| acute myocardial infarction \| 1 C0027051 \| myocardial infarction \| 1 C0024790 \| paroxysmal nocturnal hemoglobinuria \| 1 C0021400 \| influenzae \| 1 C0022661 \| chronic kidney disease \| 1 C0025295 \| pneumococcal meningitis \| 1 C0019048 \| hemoglobinuria \| 1 C0409974 \| lupus erythematosus \| 1 C0024141 \| systemic lupus erythematosus \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:1) TIRAP \| 114609 \| CTD_human
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:8) 2220 \| FCN2 \| infer 3998 \| LMAN1 \| infer 929 \| CD14 \| infer 2212 \| FCGR2A \| infer 4153 \| MBL2 \| infer 4843 \| NOS2 \| infer 7097 \| TLR2 \| infer 7099 \| TLR4 \| infer
Text Mined Gene	(Waiting for update.)
Locus	(Waiting for update.)

Disease ID	1296
Disease	pneumococcal infections
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:21) HP:0002090 \| Pneumonia \| 11 HP:0001287 \| Meningitis \| 7 HP:0002099 \| Asthma \| 3 HP:0100584 \| Endocarditis \| 2 HP:0000979 \| Purpura \| 2 HP:0006510 \| Chronic obstructive pulmonary disease \| 2 HP:0100660 \| Dyskinesis \| 1 HP:0005575 \| Hemolytic-uremic syndrome \| 1 HP:0012622 \| Chronic kidney disease \| 1 HP:0001658 \| Myocardial infarction \| 1 HP:0001746 \| Absent spleen \| 1 HP:0002721 \| Immunodeficiency \| 1 HP:0003641 \| Hemoglobin in urine \| 1 HP:0002527 \| Falls \| 1 HP:0004818 \| Paroxysmal nocturnal hemoglobinuria \| 1 HP:0006775 \| Multiple myeloma \| 1 HP:0000099 \| Glomerular nephritis \| 1 HP:0001369 \| Arthritis \| 1 HP:0002725 \| Systemic lupus erythematosus \| 1 HP:0100758 \| Gangrene \| 1 HP:0012265 \| Ciliary dyskinesia \| 1

Disease ID	1296
Disease	pneumococcal infections
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:1) C0032285 \| pneumonia \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:6)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0032269	azithromycin	D017963	83905-01-5	pneumococcal infections	MESH:D011008	marker/mechanism	11049784
C0032269	azithromycin	D017963	83905-01-5	pneumococcal infections	MESH:D011008	therapeutic	10030778
C0032269	doxycycline	D004318	564-25-0	pneumococcal infections	MESH:D011008	therapeutic	30746
C0032269	erythromycin	D004917	114-07-8	pneumococcal infections	MESH:D011008	therapeutic	1495831
C0032269	rifampin	D012293	13292-46-1	pneumococcal infections	MESH:D011008	therapeutic	1495831
C0032269	vancomycin	D014640	1404-90-6	pneumococcal infections	MESH:D011008	therapeutic	11328774

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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