PedAM

Pediatric Disease Annotations & Medicines


	pertussis

Disease ID	1169
Disease	pertussis
Definition	A suspension of killed Bordetella pertussis organisms, used for immunization against pertussis (WHOOPING COUGH). It is generally used in a mixture with diphtheria and tetanus toxoids (DTP). There is an acellular pertussis vaccine prepared from the purified antigenic components of Bordetella pertussis, which causes fewer adverse reactions than whole-cell vaccine and, like the whole-cell vaccine, is generally used in a mixture with diphtheria and tetanus toxoids. (From Dorland, 28th ed)
Synonym	pertussis vaccine pertussis vaccine (product) pertussis vaccine (substance) pertussis vaccine [chemical/ingredient] pertussis vaccines vaccine, pertussis whooping-cough vaccine
DOID	DOID:1116
UMLS	C0031237
MeSH	D010567
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:24) C0039614 \| tetanus \| 12 C0043167 \| whooping cough \| 10 C0012546 \| diphtheria \| 7 C0032285 \| pneumonia \| 4 C0020542 \| pulmonary hypertension \| 2 C0021400 \| influenza \| 2 C0026934 \| mycoplasma \| 2 C0004096 \| asthma \| 2 C0019061 \| hemolytic uremic syndrome \| 2 C0020538 \| hypertension \| 2 C0032302 \| mycoplasma pneumonia \| 1 C0004623 \| bacterial infection \| 1 C0019158 \| hepatitis \| 1 C0278883 \| metastatic melanoma \| 1 C0025202 \| melanoma \| 1 C0019163 \| hepatitis b \| 1 C0162429 \| undernutrition \| 1 C0006017 \| bordetella pertussis \| 1 C0010674 \| cystic fibrosis \| 1 C0041296 \| tuberculosis \| 1 C0013990 \| emphysema \| 1 C0025007 \| measles \| 1 C0009443 \| coryza \| 1 C0004626 \| bacterial pneumonia \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:191) 4706 \| NDUFAB1 \| DISEASES 2767 \| GNA11 \| DISEASES 151887 \| CCDC80 \| DISEASES 57026 \| PDXP \| DISEASES 84844 \| PHF5A \| DISEASES 8846 \| ALKBH1 \| DISEASES 10916 \| MAGED2 \| DISEASES 51285 \| RASL12 \| DISEASES 81576 \| CCDC130 \| DISEASES 973 \| CD79A \| DISEASES 55851 \| PSENEN \| DISEASES 5949 \| RBP3 \| DISEASES 10951 \| CBX1 \| DISEASES 51655 \| RASD1 \| DISEASES 3558 \| IL2 \| DISEASES 969 \| CD69 \| DISEASES 3458 \| IFNG \| DISEASES 8078 \| USP5 \| DISEASES 3565 \| IL4 \| DISEASES 3567 \| IL5 \| DISEASES 22924 \| MAPRE3 \| DISEASES 5507 \| PPP1R3C \| DISEASES 9479 \| MAPK8IP1 \| DISEASES 3991 \| LIPE \| DISEASES 56269 \| IRGC \| DISEASES 1236 \| CCR7 \| DISEASES 5199 \| CFP \| DISEASES 148022 \| TICAM1 \| DISEASES 2781 \| GNAZ \| DISEASES 2847 \| MCHR1 \| DISEASES 3630 \| INS \| DISEASES 64428 \| NARFL \| DISEASES 7837 \| PXDN \| DISEASES 51132 \| RLIM \| DISEASES 56033 \| BARX1 \| DISEASES 10955 \| SERINC3 \| DISEASES 269 \| AMHR2 \| DISEASES 9700 \| ESPL1 \| DISEASES 3569 \| IL6 \| DISEASES 7097 \| TLR2 \| DISEASES 5330 \| PLCB2 \| DISEASES 10017 \| BCL2L10 \| DISEASES 8099 \| CDK2AP1 \| DISEASES 6521 \| SLC4A1 \| DISEASES 2775 \| GNAO1 \| DISEASES 25939 \| SAMHD1 \| DISEASES 2769 \| GNA15 \| DISEASES 3552 \| IL1A \| DISEASES 3553 \| IL1B \| DISEASES 28960 \| DCPS \| DISEASES 3299 \| HSF4 \| DISEASES 941 \| CD80 \| DISEASES 5443 \| POMC \| DISEASES 3383 \| ICAM1 \| DISEASES 3827 \| KNG1 \| DISEASES 3371 \| TNC \| DISEASES 7416 \| VDAC1 \| DISEASES 1390 \| CREM \| DISEASES 5172 \| SLC26A4 \| DISEASES 939 \| CD27 \| DISEASES 55089 \| SLC38A4 \| DISEASES 8620 \| NPFF \| DISEASES 6751 \| SSTR1 \| DISEASES 28987 \| NOB1 \| DISEASES 963 \| CD53 \| DISEASES 805 \| CALM2 \| DISEASES 275 \| AMT \| DISEASES 6581 \| SLC22A3 \| DISEASES 53942 \| CNTN5 \| DISEASES 54842 \| MFSD6 \| DISEASES 2180 \| ACSL1 \| DISEASES 84539 \| MCHR2 \| DISEASES 84959 \| UBASH3B \| DISEASES 1562 \| CYP2C18 \| DISEASES 1436 \| CSF1R \| DISEASES 2776 \| GNAQ \| DISEASES 6750 \| SST \| DISEASES 808 \| CALM3 \| DISEASES 57465 \| TBC1D24 \| DISEASES 2215 \| FCGR3B \| DISEASES 213 \| ALB \| DISEASES 6010 \| RHO \| DISEASES 1437 \| CSF2 \| DISEASES 83550 \| GPR101 \| DISEASES 10206 \| TRIM13 \| DISEASES 322 \| APBB1 \| DISEASES 6323 \| SCN1A \| DISEASES 3596 \| IL13 \| DISEASES 5354 \| PLP1 \| DISEASES 147 \| ADRA1B \| DISEASES 1938 \| EEF2 \| DISEASES 79660 \| PPP1R3B \| DISEASES 48 \| ACO1 \| DISEASES 5029 \| P2RY2 \| DISEASES 5319 \| PLA2G1B \| DISEASES 8636 \| SSNA1 \| DISEASES 54472 \| TOLLIP \| DISEASES 3350 \| HTR1A \| DISEASES 5551 \| PRF1 \| DISEASES 6863 \| TAC1 \| DISEASES 2 \| A2M \| DISEASES 3032 \| HADHB \| DISEASES 29933 \| GPR132 \| DISEASES 1850 \| DUSP8 \| DISEASES 283869 \| NPW \| DISEASES 23542 \| MAPK8IP2 \| DISEASES 942 \| CD86 \| DISEASES 9939 \| RBM8A \| DISEASES 340075 \| ARSI \| DISEASES 3363 \| HTR7 \| DISEASES 3266 \| ERAS \| DISEASES 3329 \| HSPD1 \| DISEASES 3770 \| KCNJ14 \| DISEASES 2029 \| ENSA \| DISEASES 8780 \| RIOK3 \| DISEASES 25870 \| SUMF2 \| DISEASES 2305 \| FOXM1 \| DISEASES 3605 \| IL17A \| DISEASES 3005 \| H1F0 \| DISEASES 10202 \| DHRS2 \| DISEASES 84236 \| RHBDD1 \| DISEASES 25813 \| SAMM50 \| DISEASES 5325 \| PLAGL1 \| DISEASES 4625 \| MYH7 \| DISEASES 2204 \| FCAR \| DISEASES 3240 \| HP \| DISEASES 146059 \| CDAN1 \| DISEASES 801 \| CALM1 \| DISEASES 6752 \| SSTR2 \| DISEASES 404552 \| SCGB1D4 \| DISEASES 9652 \| TTC37 \| DISEASES 617 \| BCS1L \| DISEASES 23560 \| GTPBP4 \| DISEASES 9760 \| TOX \| DISEASES 23038 \| WDTC1 \| DISEASES 961 \| CD47 \| DISEASES 142 \| PARP1 \| DISEASES 343035 \| RD3 \| DISEASES 7432 \| VIP \| DISEASES 1805 \| DPT \| DISEASES 2214 \| FCGR3A \| DISEASES 8349 \| HIST2H2BE \| DISEASES 5406 \| PNLIP \| DISEASES 959 \| CD40LG \| DISEASES 27286 \| SRPX2 \| DISEASES 54936 \| ADPRHL2 \| DISEASES 55315 \| SLC29A3 \| DISEASES 7099 \| TLR4 \| DISEASES 83737 \| ITCH \| DISEASES 3376 \| IARS \| DISEASES 3055 \| HCK \| DISEASES 7916 \| PRRC2A \| DISEASES 22921 \| MSRB2 \| DISEASES 3980 \| LIG3 \| DISEASES 9189 \| ZBED1 \| DISEASES 2813 \| GP2 \| DISEASES 3822 \| KLRC2 \| DISEASES 116448 \| OLIG1 \| DISEASES 4155 \| MBP \| DISEASES 5888 \| RAD51 \| DISEASES 10411 \| RAPGEF3 \| DISEASES 974 \| CD79B \| DISEASES 65057 \| ACD \| DISEASES 11069 \| RAPGEF4 \| DISEASES 8786 \| RGS11 \| DISEASES 344022 \| NOTO \| DISEASES 29901 \| SAC3D1 \| DISEASES 8091 \| HMGA2 \| DISEASES 8911 \| CACNA1I \| DISEASES 6295 \| SAG \| DISEASES 7124 \| TNF \| DISEASES 25821 \| MTO1 \| DISEASES 6892 \| TAPBP \| DISEASES 4050 \| LTB \| DISEASES 3586 \| IL10 \| DISEASES 8801 \| SUCLG2 \| DISEASES 111 \| ADCY5 \| DISEASES 10189 \| ALYREF \| DISEASES 23741 \| EID1 \| DISEASES 9793 \| CKAP5 \| DISEASES 6230 \| RPS25 \| DISEASES 930 \| CD19 \| DISEASES 3684 \| ITGAM \| DISEASES 8725 \| URI1 \| DISEASES 2079 \| ERH \| DISEASES 400410 \| ST20 \| DISEASES 100287226 \| ZNF729 \| DISEASES 497634 \| LINC00293 \| DISEASES 677768 \| SCARNA13 \| DISEASES 26793 \| SNORD56 \| DISEASES 692199 \| SNORD84 \| DISEASES
Locus	(Waiting for update.)

Disease ID	1169
Disease	pertussis
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:20) HP:0012735 \| Coughing \| 37 HP:0011947 \| Respiratory infection \| 3 HP:0002104 \| Absence of spontaneous respiration \| 2 HP:0002090 \| Pneumonia \| 2 HP:0002099 \| Asthma \| 2 HP:0005575 \| Hemolytic-uremic syndrome \| 2 HP:0002861 \| Melanoma \| 1 HP:0002097 \| Pulmonary emphysema \| 1 HP:0001974 \| Leukocytosis \| 1 HP:0030828 \| Wheezing \| 1 HP:0002013 \| Emesis \| 1 HP:0011096 \| Demyelination \| 1 HP:0012115 \| Liver inflammation \| 1 HP:0000961 \| Cyanosis \| 1 HP:0002092 \| Pulmonary artery hypertension \| 1 HP:0001250 \| Seizures \| 1 HP:0003651 \| Foam cells \| 1 HP:0000822 \| Hypertension \| 1 HP:0100845 \| Anaphylactic shock \| 1 HP:0009733 \| Glioma \| 1

Disease ID	1169
Disease	pertussis
Manually Symptom	UMLS \| Name(Total Manually Symptoms:19) C2712323 \| hypoglycaemia C2712322 \| tachycardia C2707258 \| infections C1963220 \| pulmonary hypertension C1963101 \| encephalopathy C1961131 \| cough C0851887 \| adenoviral infection C0850803 \| anaphylaxis C0796095 \| c syndrome C0038826 \| superinfection C0036572 \| seizures C0032319 \| pneumopericardium C0027765 \| neurological disorders C0024282 \| lymphocytosis C0020456 \| hyperglycemia C0019080 \| hemorrhage C0018991 \| hemiplegia C0014038 \| encephalitis C0006267 \| bronchiectasis
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:5) C0010200 \| cough \| 37 C0021311 \| infections \| 8 C0796095 \| c syndrome \| 2 C0036572 \| seizures \| 1 C0020542 \| pulmonary hypertension \| 1

Manually Genotype(Total Text Mining Genotypes:0)
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All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:0)
(Waiting for update.)

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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