Definition | A syndrome of persistent PULMONARY HYPERTENSION in the newborn infant (INFANT, NEWBORN) without demonstrable HEART DISEASES. This neonatal condition can be caused by severe pulmonary vasoconstriction (reactive type), hypertrophy of pulmonary arterial muscle (hypertrophic type), or abnormally developed pulmonary arterioles (hypoplastic type). The newborn patient exhibits CYANOSIS and ACIDOSIS due to the persistence of fetal circulatory pattern of right-to-left shunting of blood through a patent ductus arteriosus (DUCTUS ARTERIOSUS, PATENT) and at times a patent foramen ovale (FORAMEN OVALE, PATENT).
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Synonym | acd mpv acd-mpv acdmpv alveolar capillary dysplasia with misalignment of pulmonary veins alveolar capillary dysplasia with misalignment of pulmonary veins and other congenital anomalies circ persistent fetal circulation, persistent fetal familial persistent pulmonary hypertension of the newborn fetal circ persistent fetal circulation fetal circulation, persistent hypertension pulm of newborn persistent hypertension, pulmonary, of newborn, persistent misalignment of the pulmonary vessels persistent fetal circ persistent fetal circulation persistent fetal circulation (disorder) persistent fetal circulation syndrome (disorder) persistent fetal circulation syndrome [disease/finding] persistent foetal circulation persistent foetal circulation syndrome persistent pulm hypertension of newborn persistent pulmonary hypertension of newborn persistent pulmonary hypertension of the newborn persistent pulmonary hypertension of the newborn (disorder) pfc - persistent fetal circulation pfc - persistent foetal circulation pfc syndrome pphn pphn - persistent pulmonary hypertension in newborn pulmonary hypertension, familial persistent, of the newborn
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