PedAM

Pediatric Disease Annotations & Medicines


	periodontitis

Disease ID	231
Disease	periodontitis
Definition	Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)
Synonym	periodontitides periodontitis (disorder) periodontitis [disease/finding] periodontitis nos periodontitis, nos pyorrhea
DOID	DOID:824
UMLS	C0031099
MeSH	D010518
SNOMED-CT	SNOMEDCT_US_2016_09_01:41565005
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:118) C0011847 \| diabetes \| 80 C0011860 \| type 2 diabetes \| 39 C0011849 \| diabetes mellitus \| 36 C0042373 \| vascular disease \| 24 C0007222 \| cardiovascular disease \| 21 C0011860 \| type 2 diabetes mellitus \| 21 C0034103 \| pulpitis \| 13 C0017574 \| gingivitis \| 13 C0028754 \| obesity \| 13 C0003873 \| rheumatoid arthritis \| 13 C0003864 \| arthritis \| 11 C0022661 \| chronic kidney disease \| 11 C0376480 \| gingival enlargement \| 10 C0018799 \| heart disease \| 9 C0022658 \| kidney disease \| 9 C0948265 \| metabolic syndrome \| 8 C0011407 \| necrotic pulp \| 8 C0010068 \| coronary heart disease \| 8 C0042373 \| vascular diseases \| 7 C0007222 \| cardiovascular diseases \| 7 C0011407 \| pulp necrosis \| 7 C0020538 \| hypertension \| 5 C0002871 \| anemia \| 5 C0010068 \| coronary artery disease \| 5 C0004153 \| atherosclerosis \| 5 C0031090 \| periodontal disease \| 4 C0033860 \| psoriasis \| 4 C0035851 \| root resorption \| 4 C0031106 \| aggressive periodontitis \| 3 C0870082 \| hyperkeratosis \| 3 C0003467 \| anxiety \| 3 C0027051 \| myocardial infarct \| 3 C0011407 \| pulpal necrosis \| 3 C0011860 \| diabetes mellitus type 2 \| 3 C0026640 \| oral cancer \| 3 C0011860 \| type ii diabetes \| 2 C0024115 \| pulmonary disease \| 2 C0376480 \| gingival overgrowth \| 2 C0155626 \| acute myocardial infarction \| 2 C0011334 \| caries \| 2 C0022658 \| kidney diseases \| 2 C0007965 \| chediak-higashi syndrome \| 2 C0003486 \| aortic aneurysm \| 2 C0040188 \| tic disorders \| 2 C0013537 \| eclampsia \| 2 C0032914 \| preeclampsia \| 2 C0085207 \| gestational diabetes \| 2 C0030360 \| papillon-lefevre syndrome \| 2 C0600260 \| obstructive pulmonary disease \| 2 C0024117 \| chronic obstructive pulmonary disease \| 2 C0029456 \| osteoporosis \| 2 C0024117 \| chronic obstructive pulmonary disease (copd) \| 2 C0027051 \| myocardial infarction \| 2 C0011854 \| type 1 diabetes \| 2 C0017572 \| gingival recession \| 2 C0007137 \| squamous cell carcinoma \| 1 C1561644 \| chronic kidney disease (ckd) \| 1 C0026636 \| oral disease \| 1 C0409974 \| lupus erythematosus \| 1 C0235974 \| pancreatic cancer \| 1 C0011860 \| diabetes type ii \| 1 C0152021 \| congenital heart disease \| 1 C0010054 \| coronary atherosclerosis \| 1 C0007785 \| cerebral ischemia \| 1 C0017567 \| gingival hypertrophy \| 1 C0002452 \| amelogenesis imperfecta \| 1 C0030809 \| pemphigus vulgaris \| 1 C0020538 \| high blood pressure \| 1 C0011570 \| depression \| 1 C0085207 \| gestational diabetes mellitus \| 1 C0221023 \| cyclic neutropenia \| 1 C0002395 \| alzheimer's disease \| 1 C0042384 \| vasculitis \| 1 C0031090 \| periodontal diseases \| 1 C0023646 \| lichen planus \| 1 C0162429 \| malnutrition \| 1 C0031030 \| apical periodontitis \| 1 C0011334 \| dental caries \| 1 C0024141 \| systemic lupus erythematosus \| 1 C0020456 \| hyperglycemia \| 1 C0442874 \| neuropathy \| 1 C0021831 \| bowel disease \| 1 C0037315 \| sleep apnea \| 1 C0014121 \| infective endocarditis \| 1 C0302592 \| carcinoma cervix \| 1 C0011436 \| dentinogenesis imperfecta \| 1 C0010346 \| crohn's disease \| 1 C0011854 \| diabetes type i \| 1 C0020456 \| high blood glucose \| 1 C0021053 \| immune disease \| 1 C0004623 \| bacterial infection \| 1 C0022116 \| ischemia \| 1 C0042870 \| vitamin d deficiency \| 1 C0162316 \| iron deficiency anemia \| 1 C0039263 \| takayasu arteritis \| 1 C0020179 \| huntington's disease \| 1 C0040451 \| tooth resorption \| 1 C0013395 \| dyspepsia \| 1 C0151744 \| ischaemic heart disease \| 1 C0041408 \| turner's syndrome \| 1 C0042974 \| von willebrand disease \| 1 C0002726 \| amyloidosis \| 1 C0027947 \| neutropenia \| 1 C0004623 \| bacterial infections \| 1 C0020443 \| hypercholesterolemia \| 1 C0004153 \| atherosclerotic vascular disease \| 1 C0014118 \| endocarditis \| 1 C0001261 \| actinomycosis \| 1 C0007137 \| squamous cell carcinomas \| 1 C0011854 \| type 1 diabetes mellitus \| 1 C0024796 \| marfan syndrome \| 1 C0023890 \| cirrhosis \| 1 C0022593 \| keratosis \| 1 C0042870 \| vitamin d defic \| 1 C0017152 \| gastritis \| 1 C0011860 \| type ii diabetes mellitus \| 1 C0021390 \| inflammatory bowel disease \| 1 C0031111 \| periostitis \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:6) CRP \| 1401 \| CTD_human MMP9 \| 4318 \| CTD_human NKAIN2 \| 154215 \| GWASCAT BIRC5 \| 332 \| GWASCAT GGT1 \| 2678 \| CTD_human GLT6D1 \| 360203 \| GWASCAT
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:98) 1636 \| ACE \| infer 183 \| AGT \| infer 185 \| AGTR1 \| infer 217 \| ALDH2 \| infer 799 \| CALCR \| infer 6352 \| CCL5 \| infer 1234 \| CCR5 \| infer 929 \| CD14 \| infer 1308 \| COL17A1 \| infer 1277 \| COL1A1 \| infer 1282 \| COL4A1 \| infer 1435 \| CSF1 \| infer 1493 \| CTLA4 \| infer 1075 \| CTSC \| infer 1509 \| CTSD \| infer 1535 \| CYBA \| infer 1543 \| CYP1A1 \| infer 1557 \| CYP2C19 \| infer 1571 \| CYP2E1 \| infer 1672 \| DEFB1 \| infer 1803 \| DPP4 \| infer 1906 \| EDN1 \| infer 1950 \| EGF \| infer 2099 \| ESR1 \| infer 356 \| FASLG \| infer 2205 \| FCER1A \| infer 2209 \| FCGR1A \| infer 2212 \| FCGR2A \| infer 2213 \| FCGR2B \| infer 2214 \| FCGR3A \| infer 2215 \| FCGR3B \| infer 2244 \| FGB \| infer 10875 \| FGL2 \| infer 2357 \| FPR1 \| infer 360203 \| GLT6D1 \| infer 2796 \| GNRH1 \| infer 2944 \| GSTM1 \| infer 2952 \| GSTT1 \| infer 3105 \| HLA-A \| infer 3106 \| HLA-B \| infer 3107 \| HLA-C \| infer 3119 \| HLA-DQB1 \| infer 3123 \| HLA-DRB1 \| infer 3126 \| HLA-DRB4 \| infer 3127 \| HLA-DRB5 \| infer 3339 \| HSPG2 \| infer 3347 \| HTN3 \| infer 3383 \| ICAM1 \| infer 29851 \| ICOS \| infer 3458 \| IFNG \| infer 3459 \| IFNGR1 \| infer 3586 \| IL10 \| infer 3596 \| IL13 \| infer 3603 \| IL16 \| infer 3606 \| IL18 \| infer 3552 \| IL1A \| infer 3553 \| IL1B \| infer 3554 \| IL1R1 \| infer 7850 \| IL1R2 \| infer 3557 \| IL1RN \| infer 3558 \| IL2 \| infer 11009 \| IL24 \| infer 3565 \| IL4 \| infer 3569 \| IL6 \| infer 3570 \| IL6R \| infer 3572 \| IL6ST \| infer 25984 \| KRT23 \| infer 4049 \| LTA \| infer 4153 \| MBL2 \| infer 4312 \| MMP1 \| infer 4321 \| MMP12 \| infer 4313 \| MMP2 \| infer 4314 \| MMP3 \| infer 4318 \| MMP9 \| infer 2206 \| MS4A2 \| infer 4524 \| MTHFR \| infer 10 \| NAT2 \| infer 64127 \| NOD2 \| infer 5295 \| PIK3R1 \| infer 5327 \| PLAT \| infer 5730 \| PTGDS \| infer 5743 \| PTGS2 \| infer 6279 \| S100A8 \| infer 5265 \| SERPINA1 \| infer 5054 \| SERPINE1 \| infer 6441 \| SFTPD \| infer 6696 \| SPP1 \| infer 7040 \| TGFB1 \| infer 7077 \| TIMP2 \| infer 7097 \| TLR2 \| infer 7099 \| TLR4 \| infer 54106 \| TLR9 \| infer 7124 \| TNF \| infer 8792 \| TNFRSF11A \| infer 4982 \| TNFRSF11B \| infer 7133 \| TNFRSF1B \| infer 8600 \| TNFSF11 \| infer 7421 \| VDR \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:468) 100048912 \| CDKN2B-AS1 \| DISEASES 920 \| CD4 \| DISEASES 1634 \| DCN \| DISEASES 9341 \| VAMP3 \| DISEASES 7984 \| ARHGEF5 \| DISEASES 83992 \| CTTNBP2 \| DISEASES 7132 \| TNFRSF1A \| DISEASES 3566 \| IL4R \| DISEASES 30009 \| TBX21 \| DISEASES 10777 \| ARPP21 \| DISEASES 2191 \| FAP \| DISEASES 22798 \| LAMB4 \| DISEASES 350 \| APOH \| DISEASES 23411 \| SIRT1 \| DISEASES 266 \| AMELY \| DISEASES 4616 \| GADD45B \| DISEASES 5008 \| OSM \| DISEASES 5594 \| MAPK1 \| DISEASES 3162 \| HMOX1 \| DISEASES 158 \| ADSL \| DISEASES 6767 \| ST13 \| DISEASES 1511 \| CTSG \| DISEASES 4792 \| NFKBIA \| DISEASES 113278 \| SLC52A3 \| DISEASES 55612 \| FERMT1 \| DISEASES 3929 \| LBP \| DISEASES 1472 \| CST4 \| DISEASES 51311 \| TLR8 \| DISEASES 7076 \| TIMP1 \| DISEASES 54 \| ACP5 \| DISEASES 4313 \| MMP2 \| DISEASES 56942 \| CMC2 \| DISEASES 10423 \| CDIPT \| DISEASES 5327 \| PLAT \| DISEASES 8797 \| TNFRSF10A \| DISEASES 56729 \| RETN \| DISEASES 2091 \| FBL \| DISEASES 7040 \| TGFB1 \| DISEASES 973 \| CD79A \| DISEASES 5444 \| PON1 \| DISEASES 3082 \| HGF \| DISEASES 10135 \| NAMPT \| DISEASES 1749 \| DLX5 \| DISEASES 10392 \| NOD1 \| DISEASES 5054 \| SERPINE1 \| DISEASES 5919 \| RARRES2 \| DISEASES 6348 \| CCL3 \| DISEASES 4353 \| MPO \| DISEASES 1440 \| CSF3 \| DISEASES 6347 \| CCL2 \| DISEASES 6357 \| CCL13 \| DISEASES 3381 \| IBSP \| DISEASES 3558 \| IL2 \| DISEASES 1075 \| CTSC \| DISEASES 5829 \| PXN \| DISEASES 51561 \| IL23A \| DISEASES 3458 \| IFNG \| DISEASES 1432 \| MAPK14 \| DISEASES 7265 \| TTC1 \| DISEASES 3565 \| IL4 \| DISEASES 3567 \| IL5 \| DISEASES 4057 \| LTF \| DISEASES 3273 \| HRG \| DISEASES 3554 \| IL1R1 \| DISEASES 566 \| AZU1 \| DISEASES 5657 \| PRTN3 \| DISEASES 6402 \| SELL \| DISEASES 1509 \| CTSD \| DISEASES 4317 \| MMP8 \| DISEASES 8600 \| TNFSF11 \| DISEASES 847 \| CAT \| DISEASES 54210 \| TREM1 \| DISEASES 718 \| C3 \| DISEASES 2658 \| GDF2 \| DISEASES 968 \| CD68 \| DISEASES 6351 \| CCL4 \| DISEASES 3630 \| INS \| DISEASES 348 \| APOE \| DISEASES 140683 \| BPIFA2 \| DISEASES 2161 \| F12 \| DISEASES 6382 \| SDC1 \| DISEASES 23135 \| KDM6B \| DISEASES 1401 \| CRP \| DISEASES 759 \| CA1 \| DISEASES 4064 \| CD180 \| DISEASES 1828 \| DSG1 \| DISEASES 80326 \| WNT10A \| DISEASES 9392 \| TGFBRAP1 \| DISEASES 3569 \| IL6 \| DISEASES 3557 \| IL1RN \| DISEASES 27177 \| IL36B \| DISEASES 170680 \| PSORS1C2 \| DISEASES 7097 \| TLR2 \| DISEASES 4316 \| MMP7 \| DISEASES 4322 \| MMP13 \| DISEASES 3706 \| ITPKA \| DISEASES 29081 \| METTL5 \| DISEASES 11213 \| IRAK3 \| DISEASES 4069 \| LYZ \| DISEASES 3839 \| KPNA3 \| DISEASES 8120 \| AP3B2 \| DISEASES 10728 \| PTGES3 \| DISEASES 4025 \| LPO \| DISEASES 7077 \| TIMP2 \| DISEASES 10325 \| RRAGB \| DISEASES 25939 \| SAMHD1 \| DISEASES 5595 \| MAPK3 \| DISEASES 10096 \| ACTR3 \| DISEASES 3552 \| IL1A \| DISEASES 3553 \| IL1B \| DISEASES 9424 \| KCNK6 \| DISEASES 3933 \| LCN1 \| DISEASES 1991 \| ELANE \| DISEASES 6403 \| SELP \| DISEASES 10382 \| TUBB4A \| DISEASES 79594 \| MUL1 \| DISEASES 941 \| CD80 \| DISEASES 59067 \| IL21 \| DISEASES 2247 \| FGF2 \| DISEASES 3589 \| IL11 \| DISEASES 7474 \| WNT5A \| DISEASES 6774 \| STAT3 \| DISEASES 3383 \| ICAM1 \| DISEASES 80321 \| CEP70 \| DISEASES 3827 \| KNG1 \| DISEASES 1950 \| EGF \| DISEASES 27074 \| LAMP3 \| DISEASES 6595 \| SMARCA2 \| DISEASES 55749 \| CCAR1 \| DISEASES 7078 \| TIMP3 \| DISEASES 2252 \| FGF7 \| DISEASES 3067 \| HDC \| DISEASES 597 \| BCL2A1 \| DISEASES 3687 \| ITGAX \| DISEASES 3394 \| IRF8 \| DISEASES 6687 \| SPG7 \| DISEASES 79755 \| ZNF750 \| DISEASES 207 \| AKT1 \| DISEASES 8547 \| FCN3 \| DISEASES 2212 \| FCGR2A \| DISEASES 1513 \| CTSK \| DISEASES 4794 \| NFKBIE \| DISEASES 908 \| CCT6A \| DISEASES 3934 \| LCN2 \| DISEASES 4851 \| NOTCH1 \| DISEASES 133 \| ADM \| DISEASES 7762 \| ZNF215 \| DISEASES 22917 \| ZP1 \| DISEASES 90952 \| ESAM \| DISEASES 128506 \| OCSTAMP \| DISEASES 3606 \| IL18 \| DISEASES 166785 \| MMAA \| DISEASES 5741 \| PTH \| DISEASES 925 \| CD8A \| DISEASES 23643 \| LY96 \| DISEASES 760 \| CA2 \| DISEASES 761 \| CA3 \| DISEASES 245972 \| ATP6V0D2 \| DISEASES 123720 \| WHAMM \| DISEASES 10694 \| CCT8 \| DISEASES 163786 \| SASS6 \| DISEASES 7079 \| TIMP4 \| DISEASES 146433 \| IL34 \| DISEASES 729230 \| CCR2 \| DISEASES 1234 \| CCR5 \| DISEASES 5731 \| PTGER1 \| DISEASES 6352 \| CCL5 \| DISEASES 6368 \| CCL23 \| DISEASES 58191 \| CXCL16 \| DISEASES 81570 \| CLPB \| DISEASES 7412 \| VCAM1 \| DISEASES 2215 \| FCGR3B \| DISEASES 3577 \| CXCR1 \| DISEASES 213 \| ALB \| DISEASES 2921 \| CXCL3 \| DISEASES 6374 \| CXCL5 \| DISEASES 1230 \| CCR1 \| DISEASES 22824 \| HSPA4L \| DISEASES 308 \| ANXA5 \| DISEASES 10085 \| EDIL3 \| DISEASES 2150 \| F2RL1 \| DISEASES 1437 \| CSF2 \| DISEASES 4982 \| TNFRSF11B \| DISEASES 1672 \| DEFB1 \| DISEASES 81501 \| DCSTAMP \| DISEASES 63876 \| PKNOX2 \| DISEASES 79841 \| AGBL2 \| DISEASES 64112 \| MOAP1 \| DISEASES 5055 \| SERPINB2 \| DISEASES 4314 \| MMP3 \| DISEASES 64127 \| NOD2 \| DISEASES 56547 \| MMP26 \| DISEASES 762 \| CA4 \| DISEASES 342574 \| KRT27 \| DISEASES 50964 \| SOST \| DISEASES 23087 \| TRIM35 \| DISEASES 6356 \| CCL11 \| DISEASES 10879 \| SMR3B \| DISEASES 2357 \| FPR1 \| DISEASES 2990 \| GUSB \| DISEASES 121340 \| SP7 \| DISEASES 5734 \| PTGER4 \| DISEASES 3689 \| ITGB2 \| DISEASES 3688 \| ITGB1 \| DISEASES 1673 \| DEFB4A \| DISEASES 126295 \| ZNF57 \| DISEASES 51237 \| MZB1 \| DISEASES 1493 \| CTLA4 \| DISEASES 23246 \| BOP1 \| DISEASES 3596 \| IL13 \| DISEASES 150468 \| CKAP2L \| DISEASES 3627 \| CXCL10 \| DISEASES 2353 \| FOS \| DISEASES 23261 \| CAMTA1 \| DISEASES 1470 \| CST2 \| DISEASES 4323 \| MMP14 \| DISEASES 24146 \| CLDN15 \| DISEASES 5340 \| PLG \| DISEASES 5222 \| PGA5 \| DISEASES 763 \| CA5A \| DISEASES 3849 \| KRT2 \| DISEASES 836 \| CASP3 \| DISEASES 7368 \| UGT8 \| DISEASES 1240 \| CMKLR1 \| DISEASES 3952 \| LEP \| DISEASES 258 \| AMBN \| DISEASES 713 \| C1QB \| DISEASES 767 \| CA8 \| DISEASES 931 \| MS4A1 \| DISEASES 1191 \| CLU \| DISEASES 30835 \| CD209 \| DISEASES 3936 \| LCP1 \| DISEASES 260436 \| FDCSP \| DISEASES 6936 \| GCFC2 \| DISEASES 3579 \| CXCR2 \| DISEASES 9370 \| ADIPOQ \| DISEASES 140596 \| DEFB104A \| DISEASES 23765 \| IL17RA \| DISEASES 414325 \| DEFB103A \| DISEASES 6863 \| TAC1 \| DISEASES 5345 \| SERPINF2 \| DISEASES 503618 \| DEFB104B \| DISEASES 3039 \| HBA1 \| DISEASES 4312 \| MMP1 \| DISEASES 4289 \| MKLN1 \| DISEASES 7706 \| TRIM25 \| DISEASES 2 \| A2M \| DISEASES 55894 \| DEFB103B \| DISEASES 404203 \| SPINK6 \| DISEASES 2200 \| FBN1 \| DISEASES 9622 \| KLK4 \| DISEASES 4843 \| NOS2 \| DISEASES 55258 \| THNSL2 \| DISEASES 1435 \| CSF1 \| DISEASES 4772 \| NFATC1 \| DISEASES 64806 \| IL25 \| DISEASES 9241 \| NOG \| DISEASES 1668 \| DEFA3 \| DISEASES 8905 \| AP1S2 \| DISEASES 10456 \| HAX1 \| DISEASES 50616 \| IL22 \| DISEASES 5121 \| PCP4 \| DISEASES 8651 \| SOCS1 \| DISEASES 286753 \| TUSC5 \| DISEASES 9021 \| SOCS3 \| DISEASES 6401 \| SELE \| DISEASES 942 \| CD86 \| DISEASES 5104 \| SERPINA5 \| DISEASES 79581 \| SLC52A2 \| DISEASES 682 \| BSG \| DISEASES 3840 \| KPNA4 \| DISEASES 353345 \| GPR141 \| DISEASES 8856 \| NR1I2 \| DISEASES 145447 \| ABHD12B \| DISEASES 114548 \| NLRP3 \| DISEASES 112744 \| IL17F \| DISEASES 64386 \| MMP25 \| DISEASES 7189 \| TRAF6 \| DISEASES 3572 \| IL6ST \| DISEASES 66005 \| CHID1 \| DISEASES 857 \| CAV1 \| DISEASES 6002 \| RGS12 \| DISEASES 3329 \| HSPD1 \| DISEASES 7100 \| TLR5 \| DISEASES 2358 \| FPR2 \| DISEASES 55552 \| ZNF823 \| DISEASES 401138 \| AMTN \| DISEASES 2804 \| GOLGB1 \| DISEASES 81545 \| FBXO38 \| DISEASES 1508 \| CTSB \| DISEASES 6590 \| SLPI \| DISEASES 145264 \| SERPINA12 \| DISEASES 9536 \| PTGES \| DISEASES 921 \| CD5 \| DISEASES 3146 \| HMGB1 \| DISEASES 3716 \| JAK1 \| DISEASES 389400 \| GFRAL \| DISEASES 3836 \| KPNA1 \| DISEASES 3605 \| IL17A \| DISEASES 1499 \| CTNNB1 \| DISEASES 5606 \| MAP2K3 \| DISEASES 89790 \| SIGLEC10 \| DISEASES 80142 \| PTGES2 \| DISEASES 766 \| CA7 \| DISEASES 2879 \| GPX4 \| DISEASES 5154 \| PDGFA \| DISEASES 728 \| C5AR1 \| DISEASES 57596 \| BEGAIN \| DISEASES 100506658 \| OCLN \| DISEASES 2204 \| FCAR \| DISEASES 5265 \| SERPINA1 \| DISEASES 6840 \| SVIL \| DISEASES 3240 \| HP \| DISEASES 7068 \| THRB \| DISEASES 344752 \| AADACL2 \| DISEASES 5733 \| PTGER3 \| DISEASES 2224 \| FDPS \| DISEASES 3683 \| ITGAL \| DISEASES 60 \| ACTB \| DISEASES 6597 \| SMARCA4 \| DISEASES 54879 \| ST7L \| DISEASES 2213 \| FCGR2B \| DISEASES 6364 \| CCL20 \| DISEASES 799 \| CALCR \| DISEASES 126014 \| OSCAR \| DISEASES 3123 \| HLA-DRB1 \| DISEASES 5599 \| MAPK8 \| DISEASES 1803 \| DPP4 \| DISEASES 54106 \| TLR9 \| DISEASES 10319 \| LAMC3 \| DISEASES 6772 \| STAT1 \| DISEASES 133308 \| SLC9B2 \| DISEASES 7096 \| TLR1 \| DISEASES 54737 \| MPHOSPH8 \| DISEASES 3775 \| KCNK1 \| DISEASES 2058 \| EPRS \| DISEASES 1378 \| CR1 \| DISEASES 9641 \| IKBKE \| DISEASES 10090 \| UST \| DISEASES 5743 \| PTGS2 \| DISEASES 3459 \| IFNGR1 \| DISEASES 26002 \| MOXD1 \| DISEASES 2214 \| FCGR3A \| DISEASES 9447 \| AIM2 \| DISEASES 632 \| BGLAP \| DISEASES 3570 \| IL6R \| DISEASES 6280 \| S100A9 \| DISEASES 1520 \| CTSS \| DISEASES 639 \| PRDM1 \| DISEASES 914 \| CD2 \| DISEASES 90025 \| UBE3D \| DISEASES 3654 \| IRAK1 \| DISEASES 1137 \| CHRNA4 \| DISEASES 2258 \| FGF13 \| DISEASES 959 \| CD40LG \| DISEASES 1791 \| DNTT \| DISEASES 3725 \| JUN \| DISEASES 860 \| RUNX2 \| DISEASES 29952 \| DPP7 \| DISEASES 360203 \| GLT6D1 \| DISEASES 7422 \| VEGFA \| DISEASES 958 \| CD40 \| DISEASES 4318 \| MMP9 \| DISEASES 5328 \| PLAU \| DISEASES 6406 \| SEMG1 \| DISEASES 57158 \| JPH2 \| DISEASES 29889 \| GNL2 \| DISEASES 139322 \| APOOL \| DISEASES 2022 \| ENG \| DISEASES 553115 \| PEF1 \| DISEASES 4153 \| MBL2 \| DISEASES 22943 \| DKK1 \| DISEASES 7099 \| TLR4 \| DISEASES 6676 \| SPAG4 \| DISEASES 164091 \| PAQR7 \| DISEASES 119180 \| LYZL2 \| DISEASES 23569 \| PADI4 \| DISEASES 11240 \| PADI2 \| DISEASES 4758 \| NEU1 \| DISEASES 10673 \| TNFSF13B \| DISEASES 4795 \| NFKBIL1 \| DISEASES 50943 \| FOXP3 \| DISEASES 9375 \| TM9SF2 \| DISEASES 3105 \| HLA-A \| DISEASES 1471 \| CST3 \| DISEASES 386653 \| IL31 \| DISEASES 765 \| CA6 \| DISEASES 285641 \| SLC36A3 \| DISEASES 6354 \| CCL7 \| DISEASES 650 \| BMP2 \| DISEASES 9308 \| CD83 \| DISEASES 2625 \| GATA3 \| DISEASES 1906 \| EDN1 \| DISEASES 10631 \| POSTN \| DISEASES 10670 \| RRAGA \| DISEASES 51284 \| TLR7 \| DISEASES 265 \| AMELX \| DISEASES 90865 \| IL33 \| DISEASES 29126 \| CD274 \| DISEASES 51199 \| NIN \| DISEASES 80333 \| KCNIP4 \| DISEASES 752014 \| CEMP1 \| DISEASES 1667 \| DEFA1 \| DISEASES 728358 \| DEFA1B \| DISEASES 440163 \| RNASE13 \| DISEASES 56953 \| NT5M \| DISEASES 284266 \| SIGLEC15 \| DISEASES 6370 \| CCL25 \| DISEASES 2113 \| ETS1 \| DISEASES 2591 \| GALNT3 \| DISEASES 6696 \| SPP1 \| DISEASES 2919 \| CXCL1 \| DISEASES 6387 \| CXCL12 \| DISEASES 528 \| ATP6V1C1 \| DISEASES 655 \| BMP7 \| DISEASES 10117 \| ENAM \| DISEASES 114884 \| OSBPL10 \| DISEASES 84807 \| NFKBID \| DISEASES 594857 \| NPS \| DISEASES 729857 \| RGPD2 \| DISEASES 54826 \| GIN1 \| DISEASES 150365 \| MEI1 \| DISEASES 7018 \| TF \| DISEASES 554226 \| ANKRD30BL \| DISEASES 7852 \| CXCR4 \| DISEASES 57703 \| CWC22 \| DISEASES 50626 \| CYHR1 \| DISEASES 10941 \| UGT2A1 \| DISEASES 23210 \| JMJD6 \| DISEASES 10725 \| NFAT5 \| DISEASES 960 \| CD44 \| DISEASES 7124 \| TNF \| DISEASES 3491 \| CYR61 \| DISEASES 4615 \| MYD88 \| DISEASES 4049 \| LTA \| DISEASES 388372 \| CCL4L1 \| DISEASES 2821 \| GPI \| DISEASES 9498 \| SLC4A8 \| DISEASES 55655 \| NLRP2 \| DISEASES 834 \| CASP1 \| DISEASES 448835 \| LCE6A \| DISEASES 3586 \| IL10 \| DISEASES 5478 \| PPIA \| DISEASES 127933 \| UHMK1 \| DISEASES 6949 \| TCOF1 \| DISEASES 2638 \| GC \| DISEASES 100289462 \| DEFB4B \| DISEASES 9140 \| ATG12 \| DISEASES 727897 \| MUC5B \| DISEASES 930 \| CD19 \| DISEASES 9414 \| TJP2 \| DISEASES 1232 \| CCR3 \| DISEASES 3684 \| ITGAM \| DISEASES 7421 \| VDR \| DISEASES 8972 \| MGAM \| DISEASES 8778 \| SIGLEC5 \| DISEASES 728276 \| CLEC19A \| DISEASES 820 \| CAMP \| DISEASES 1506 \| CTRL \| DISEASES 8792 \| TNFRSF11A \| DISEASES 54757 \| FAM20A \| DISEASES 246734 \| NPCDR1 \| DISEASES 6689 \| SPIB \| DISEASES 11012 \| KLK11 \| DISEASES 100302740 \| FAS-AS1 \| DISEASES 3262 \| HPVC1 \| DISEASES 79104 \| MEG8 \| DISEASES 100873918 \| MME-AS1 \| DISEASES
Locus	(Waiting for update.)

Disease ID	231
Disease	periodontitis
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:85) HP:0000819 \| Diabetes mellitus \| 36 HP:0000230 \| Inflamed gums \| 17 HP:0000212 \| Gingival overgrowth \| 14 HP:0001370 \| Rheumatoid arthritis \| 13 HP:0001513 \| Obesity \| 13 HP:0001369 \| Arthritis \| 11 HP:0012622 \| Chronic kidney disease \| 11 HP:0006480 \| Premature loss of teeth \| 7 HP:0000169 \| Gingival fibrous nodules \| 5 HP:0000855 \| Insulin resistance \| 5 HP:0002621 \| Atherosclerosis \| 5 HP:0001903 \| Anemia \| 5 HP:0001677 \| Coronary artery disease \| 5 HP:0000822 \| Hypertension \| 5 HP:0012531 \| Pain \| 4 HP:0003765 \| Psoriasis \| 4 HP:0007556 \| Plantar hyperkeratoses \| 4 HP:0010885 \| Aseptic necrosis \| 4 HP:0002664 \| Neoplasia \| 4 HP:0001622 \| Premature delivery \| 4 HP:0001297 \| Cerebral vascular events \| 3 HP:0000962 \| Hyperkeratosis \| 3 HP:0000972 \| Thick palms and soles \| 3 HP:0000739 \| Anxiety \| 3 HP:0003074 \| High blood glucose \| 2 HP:0000939 \| Osteoporosis \| 2 HP:0100033 \| Tic disorder \| 2 HP:0001658 \| Myocardial infarction \| 2 HP:0000700 \| Periapical radiolucency \| 2 HP:0003077 \| Hyperlipidemia \| 2 HP:0004942 \| Aortic aneurysm \| 2 HP:0030816 \| Gum recession \| 2 HP:0100601 \| Eclampsia \| 2 HP:0001518 \| Small for gestational age \| 2 HP:0100602 \| Pre-eclampsia \| 2 HP:0009800 \| gestational diabetes \| 2 HP:0000670 \| Dental caries \| 2 HP:0006510 \| Chronic obstructive pulmonary disease \| 2 HP:0012592 \| Albuminuria \| 2 HP:0010296 \| Ankyloglossia \| 1 HP:0000703 \| Dentinogenesis imperfecta \| 1 HP:0011069 \| Extra teeth \| 1 HP:0003124 \| Elevated serum cholesterol \| 1 HP:0100512 \| Vitamin D deficiency \| 1 HP:0011088 \| Dens invaginatus \| 1 HP:0005549 \| Low blood neutrophil level since birth \| 1 HP:0006349 \| Agenesis of permanent dentition \| 1 HP:0001875 \| Neutropenia \| 1 HP:0001548 \| Overgrowth \| 1 HP:0030731 \| Carcinoma \| 1 HP:0003073 \| Hypoalbuminaemia \| 1 HP:0030756 \| Erythrodontia \| 1 HP:0003207 \| Arterial calcification \| 1 HP:0005263 \| Gastritis \| 1 HP:0003287 \| Abnormality of mitochondrial metabolism \| 1 HP:0000716 \| Depression \| 1 HP:0004943 \| Accelerated atherosclerosis \| 1 HP:0003159 \| Hyperoxaluria \| 1 HP:0100543 \| Cognitive deficits \| 1 HP:0002020 \| Heartburn \| 1 HP:0000752 \| Hyperactive behavior \| 1 HP:0004395 \| Malnutrition \| 1 HP:0000674 \| Anodontia \| 1 HP:0000705 \| Amelogenesis imperfecta \| 1 HP:0010535 \| Sleep apnea \| 1 HP:0011034 \| Amyloid disease \| 1 HP:0002633 \| Vasculitis \| 1 HP:0004929 \| Coronary artherosclerosis \| 1 HP:0012743 \| Central obesity \| 1 HP:0001394 \| Hepatic cirrhosis \| 1 HP:0002860 \| Squamous cell carcinoma \| 1 HP:0001891 \| Iron-deficiency anemia \| 1 HP:0100523 \| Hepatic abscess \| 1 HP:0002725 \| Systemic lupus erythematosus \| 1 HP:0000225 \| Gingival hemorrhage \| 1 HP:0040165 \| Periostitis \| 1 HP:0002894 \| Neoplasia of the pancreas \| 1 HP:0002637 \| Brain ischemia \| 1 HP:0005978 \| Noninsulin dependent diabetes mellitus \| 1 HP:0006689 \| Bacterial endocarditis \| 1 HP:0100280 \| Morbus Crohn \| 1 HP:0002960 \| Autoimmune condition \| 1 HP:0012649 \| Increased inflammatory response \| 1 HP:0100584 \| Endocarditis \| 1 HP:0003401 \| Paresthesia \| 1

Disease ID	231
Disease	periodontitis
Manually Symptom	UMLS \| Name(Total Manually Symptoms:38) C2707258 \| infections C2598155 \| pain C2364133 \| infection C1555754 \| cardiovascular disease C1531605 \| aspergillus endophthalmitis C1510420 \| cavities C0948075 \| anal infection C0728936 \| circulatory disorders C0442886 \| secondary infection C0399452 \| supragingival plaque C0399451 \| subgingival plaque C0376480 \| gingival overgrowth C0376480 \| gingival enlargement C0242339 \| dyslipidemia C0238790 \| bone destruction C0162644 \| root caries C0151436 \| leukocytoclastic vasculitis C0080233 \| tooth loss C0042769 \| viral infections C0038454 \| stroke C0034065 \| pulmonary embolism C0031306 \| phagocytic dysfunction C0031085 \| periodontal abscesses C0030809 \| pemphigus vulgaris C0029443 \| osteomyelitis C0025517 \| metabolic disorders C0021053 \| immune system disorders C0020473 \| hyperlipidemia C0017574 \| gingivitis C0017566 \| gingival hyperplasia C0011860 \| diabetes C0011389 \| dental plaque C0011330 \| dental calculus C0004610 \| bacteremias C0004610 \| bacteraemia C0004153 \| atherosclerosis C0002382 \| periodontal bone loss C0002382 \| alveolar bone loss
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:22) C0011847 \| diabetes \| 80 C0080233 \| tooth loss \| 27 C0007222 \| cardiovascular disease \| 21 C0399451 \| subgingival plaque \| 18 C0002382 \| alveolar bone loss \| 16 C0009450 \| infection \| 16 C0017574 \| gingivitis \| 13 C0376480 \| gingival enlargement \| 10 C0021311 \| infections \| 6 C0242339 \| dyslipidemia \| 5 C0004153 \| atherosclerosis \| 5 C0238790 \| bone destruction \| 4 C0030193 \| pain \| 4 C0038454 \| stroke \| 3 C0011389 \| dental plaque \| 2 C0002382 \| periodontal bone loss \| 2 C0017566 \| gingival hyperplasia \| 2 C0376480 \| gingival overgrowth \| 2 C0020473 \| hyperlipidemia \| 2 C0030809 \| pemphigus vulgaris \| 1 C0025517 \| metabolic disorders \| 1 C0948075 \| anal infection \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:27)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs10484879	23323524	3605	IL17A	umls:C0031099	BeFree	The CC genotype of IL17 polymorphism (rs10484879) may contribute to the pathogenesis of peri-implantitis and periodontitis.	0.00953026	2013	IL17A	6	52187159	G	T
rs11536889	22661708	7099	TLR4	umls:C0031099	BeFree	We have previously shown that a single nucleotide polymorphism rs11536889 in the 3'-untranslated region (UTR) of TLR4 was associated with periodontitis.	0.03073774	2012	TLR4	9	117715853	G	C
rs1537415	19897590	360203	GLT6D1	umls:C0031099	GAD	[A genome-wide association study identifies GLT6D1 as a susceptibility locus for periodontitis.]	0.122909916	2010	GLT6D1	9	135637876	G	C
rs1537415	19897590	360203	GLT6D1	umls:C0031099	GWASCAT	A genome-wide association study identifies GLT6D1 as a susceptibility locus for periodontitis.	0.122909916	2010	GLT6D1	9	135637876	G	C
rs16944	20399512	3553	IL1B	umls:C0031099	GAD	[Dominance of environmental factors over genetic ones and insufficient sample size might explain the fragility of this studys results. Nevertheless, the association between NTM lymphadenitis and 3953CT, a polymorphism previously linked to periodontitis, su]	0.177925095	2010	IL1B	2	112837290	A	G
rs17879146	24024966	332	BIRC5	umls:C0031099	GWASCAT	Genome-wide association study of chronic periodontitis in a general German population.	0.12	2013	BIRC5	17	78223864	T	G
rs1800629	21846573	7124	TNF	umls:C0031099	BeFree	We found a strong association only between TNF rs1800629 and diffused forms of periodontitis.	0.047306964	2011	TNF	6	31575254	G	A
rs1800896	12631183	3586	IL10	umls:C0031099	GAD	[ It is suggested that the -1087 IL10 polymorphism in Caucasian subjects of a north European origin is associated with severe chronic periodontitis.]	0.11010898	2003	IL10	1	206773552	T	C
rs1800896	20399512	3586	IL10	umls:C0031099	GAD	[Dominance of environmental factors over genetic ones and insufficient sample size might explain the fragility of this studys results. Nevertheless, the association between NTM lymphadenitis and 3953CT, a polymorphism previously linked to periodontitis, su]	0.11010898	2010	IL10	1	206773552	T	C
rs1801274	23649770	1191	CLU	umls:C0031099	BeFree	Associations between FCGR2A rs1801274, FCGR3A rs396991, FCGR3B NA1/NA2 polymorphisms and periodontitis: a meta-analysis.	0.000542884	2013	FCGR2A	1	161509955	A	G
rs2234663	22370044	3557	IL1RN	umls:C0031099	BeFree	Interleukin-1 receptor antagonist polymorphism (rs2234663) and periodontitis susceptibility: a meta-analysis.	0.022660497	2012	NA	NA	NA	NA	NA
rs2392510	25672891	56479	KCNQ5	umls:C0031099	BeFree	Although single-nucleotide polymorphisms that surpassed a stringent genome-wide significance threshold (P < 5 × 10(-8)) were not identified, we found 2 suggestive loci for periodontitis: KCNQ5 on chromosome 6q13 (rs9446777, P = 4.83 × 10(-6), odds ratio = 0.82) and GPR141-NME8 at chromosome 7p14.1 (rs2392510, P = 4.17 × 10(-6), odds ratio = 0.87).	0.000271442	2015	GPR141	7	37706967	C	T
rs30461	25255471	282618	IFNL1	umls:C0031099	BeFree	Increased quantity of IL-29 in GCF and plasma of subjects with periodontitis suggests a role in pathogenesis of periodontitis and the SNP (rs30461) is not related to susceptibility to periodontitis in this population of Indian individuals.	0.000271442	2014	IFNL1	19	39298475	A	G
rs396991	23649770	1191	CLU	umls:C0031099	BeFree	Associations between FCGR2A rs1801274, FCGR3A rs396991, FCGR3B NA1/NA2 polymorphisms and periodontitis: a meta-analysis.	0.000542884	2013	FCGR3A	1	161544752	A	G,C
rs4986790	15875057	7097	TLR2	umls:C0031099	BeFree	We screened 197 individuals suffering from generalized periodontitis for the presence of Asp299Gly and Thr399Ile of TLR-4 as well as Arg753Gln of TLR-2 in comparison to matched controls.	0.017359805	2005	TLR4	9	117713024	A	G
rs4986790	15875057	7099	TLR4	umls:C0031099	BeFree	We screened 197 individuals suffering from generalized periodontitis for the presence of Asp299Gly and Thr399Ile of TLR-4 as well as Arg753Gln of TLR-2 in comparison to matched controls.	0.03073774	2005	TLR4	9	117713024	A	G
rs4986790	18618036	7099	TLR4	umls:C0031099	BeFree	The prevalence of TLR2 Arp677Trp polymorphism seemed to be rather high, while that of TLR4 Asp299Gly and Thr399Ile polymorphisms seemed to be rather low in the Chinese population, which did not permit any conclusion regarding its effects on periodontitis.	0.03073774	2008	TLR4	9	117713024	A	G
rs4986790	17309585	7099	TLR4	umls:C0031099	BeFree	No differences were found in the prevalence of the TLR4 Asp299Gly genotype in men with CP (18.9%) compared with an age-matched control group with no evidence of periodontitis (17%).	0.03073774	2007	TLR4	9	117713024	A	G
rs4986790	18618036	7097	TLR2	umls:C0031099	BeFree	The prevalence of TLR2 Arp677Trp polymorphism seemed to be rather high, while that of TLR4 Asp299Gly and Thr399Ile polymorphisms seemed to be rather low in the Chinese population, which did not permit any conclusion regarding its effects on periodontitis.	0.017359805	2008	TLR4	9	117713024	A	G
rs4986791	15875057	7097	TLR2	umls:C0031099	BeFree	We screened 197 individuals suffering from generalized periodontitis for the presence of Asp299Gly and Thr399Ile of TLR-4 as well as Arg753Gln of TLR-2 in comparison to matched controls.	0.017359805	2005	TLR4	9	117713324	C	T
rs4986791	18618036	7099	TLR4	umls:C0031099	BeFree	The prevalence of TLR2 Arp677Trp polymorphism seemed to be rather high, while that of TLR4 Asp299Gly and Thr399Ile polymorphisms seemed to be rather low in the Chinese population, which did not permit any conclusion regarding its effects on periodontitis.	0.03073774	2008	TLR4	9	117713324	C	T
rs4986791	15875057	7099	TLR4	umls:C0031099	BeFree	We screened 197 individuals suffering from generalized periodontitis for the presence of Asp299Gly and Thr399Ile of TLR-4 as well as Arg753Gln of TLR-2 in comparison to matched controls.	0.03073774	2005	TLR4	9	117713324	C	T
rs4986791	18618036	7097	TLR2	umls:C0031099	BeFree	The prevalence of TLR2 Arp677Trp polymorphism seemed to be rather high, while that of TLR4 Asp299Gly and Thr399Ile polymorphisms seemed to be rather low in the Chinese population, which did not permit any conclusion regarding its effects on periodontitis.	0.017359805	2008	TLR4	9	117713324	C	T
rs5743708	15875057	7099	TLR4	umls:C0031099	BeFree	We screened 197 individuals suffering from generalized periodontitis for the presence of Asp299Gly and Thr399Ile of TLR-4 as well as Arg753Gln of TLR-2 in comparison to matched controls.	0.03073774	2005	TLR2	4	153705165	G	A
rs5743708	15875057	7097	TLR2	umls:C0031099	BeFree	We screened 197 individuals suffering from generalized periodontitis for the presence of Asp299Gly and Thr399Ile of TLR-4 as well as Arg753Gln of TLR-2 in comparison to matched controls.	0.017359805	2005	TLR2	4	153705165	G	A
rs77490164	24024966	154215	NKAIN2	umls:C0031099	GWASCAT	Genome-wide association study of chronic periodontitis in a general German population.	0.12	2013	NKAIN2	6	124238586	C	T
rs9446777	25672891	56479	KCNQ5	umls:C0031099	BeFree	Although single-nucleotide polymorphisms that surpassed a stringent genome-wide significance threshold (P < 5 × 10(-8)) were not identified, we found 2 suggestive loci for periodontitis: KCNQ5 on chromosome 6q13 (rs9446777, P = 4.83 × 10(-6), odds ratio = 0.82) and GPR141-NME8 at chromosome 7p14.1 (rs2392510, P = 4.17 × 10(-6), odds ratio = 0.87).	0.000271442	2015	KCNQ5	6	72871328	A	G

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:282)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
1	7521585	rs1616122	C	T	rs1616122	22699663	5.00E-06	Orange	1.85	[1.41-2.42]	1,020 European ancestry individuals	European(1020)	ALL(1020)	EUR(1020)	ALL(1020)	Periodontal microbiota	HPOID:0000168	Abnormality of the gingiva	DOID:824	periodontitis	D055113	Chronic Periodontitis	NA	NA	Periodontitis	rs1616122-T	Research Support, N.I.H., Extramural	G	CAMTA1
1	60615397	rs618570	G	C	rs618570	24024966	4.98E-06	Age 20-60 years	1.77	[1.39-2.27]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs618570-C	NA	C	NA
1	60615839	rs620794	G	C	rs620794	24024966	4.99E-06	Age 20-60 years	1.77	[1.39-2.27]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs620794-C	NA	C	NA
1	60631000	rs922356	G	A	rs922356	24024966	4.68E-06	Age 20-60 years	1.79	[1.39-2.27]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	G	NA
1	60634158	rs17120284	G	T	rs17120284	24024966	4.54E-06	Age 20-60 years	1.79	[1.39-2.27]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	G	NA
1	60639683	rs12072323	G	T	rs12072323	24024966	4.65E-06	Age 20-60 years	1.79	[1.39-2.27]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	G	NA
1	60661493	rs7534167	G	T	rs7534167	24024966	4.35E-06	Age 20-60 years	1.79	[1.39-2.27]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	G	NA
1	60667936	rs7530841	A	C	rs7530841	24024966	4.35E-06	Age 20-60 years	1.78	[1.39-2.27]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs7530841-A	NA	A	NA
1	60669529	rs1381890	T	C	rs1381890	24024966	4.55E-06	Age 20-60 years	1.78	[1.39-2.27]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs1381890-T	NA	T	NA
1	60671732	rs17120349	G	T	rs17120349	24024966	3.83E-06	Age 20-60 years	1.79	[1.39-2.27]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	G	NA
1	60681873	rs12081932	C	T	rs12081932	24024966	4.32E-06	Age 20-60 years	1.79	[1.39-2.27]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	C	NA
1	60691150	rs11207580	G	T	rs11207580	24024966	4.31E-06	Age 20-60 years	1.79	[1.39-2.27]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	G	NA
1	60691588	rs17120400	G	A	rs17120400	24024966	4.00E-06	Age 20-60 years	1.69	[1.35-2.13]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	A	NA
1	88625636	rs12032672	A	C	rs12032672	22699663	1.00E-06	Red	1.99	[1.50-2.62]	1,020 European ancestry individuals	European(1020)	ALL(1020)	EUR(1020)	ALL(1020)	Periodontal microbiota	HPOID:0000168	Abnormality of the gingiva	DOID:824	periodontitis	D055113	Chronic Periodontitis	NA	NA	Periodontitis	rs12032672-C	Research Support, N.I.H., Extramural	A	NA
1	115196166	rs10858049	A	G	rs10858049	25008200	9.54E-05	NA	NA	NA	63 European ancestry cases; 543 European ancestry controls; up to 32 African American cases; up to 158 African American controls; up to 4 cases; up to 66 controls	NOPOP(70)	African American(190)	European(606)	ALL(866)	NOPOP(70)	AFR(190)	EUR(606)	ALL(866)	Periodontitis (Chronic)	NA	NA	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis
1	204101681	rs1917540	C	T	rs1917540	24024966	6.45E-06	Age 20-60 years	1.35	[1.18-1.52]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	C	ETNK2
1	204103618	rs2293335	G	A	rs2293335	24024966	5.00E-06	Age 20-60 years	1.35	[1.19-1.54]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	G	ETNK2
1	204109473	rs11240680	G	A	rs11240680	24024966	7.94E-06	Age 20-60 years	1.35	[1.19-1.54]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	G	ETNK2
1	233719984	rs11800854	G	A	rs11800854	22699663	3.00E-07	Red	12.3	[3.70-41.30]	1,020 European ancestry individuals	European(1020)	ALL(1020)	EUR(1020)	ALL(1020)	Periodontal microbiota	HPOID:0000168	Abnormality of the gingiva	DOID:824	periodontitis	D055113	Chronic Periodontitis	NA	NA	Periodontitis	rs11800854-G	Research Support, N.I.H., Extramural	G	NA
1	233719984	rs11800854	G	A	rs11800854	22699663	4.00E-06	A. actino	8.12	[2.73-24.11]	1,020 European ancestry individuals	European(1020)	ALL(1020)	EUR(1020)	ALL(1020)	Periodontal microbiota	HPOID:0000168	Abnormality of the gingiva	DOID:824	periodontitis	D055113	Chronic Periodontitis	NA	NA	Periodontitis	rs11800854-G	Research Support, N.I.H., Extramural	G	NA
1	236912057	rs12048046	T	C	rs12048046	24024966	3.00E-06	Age 20-81 years	1.52	[1.28-1.81]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs12048046-T	NA	T	ACTN2
1	236912597	rs2297955	A	G	rs2297955	24024966	3.42E-06	Age 20-81 years	1.52	[1.27-1.81]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs2297955-A	NA	T	ACTN2
2	26782621	rs1011108	C	T	rs1011108	22699663	2.00E-06	P. gingi	1.79	[1.40-2.27]	1,020 European ancestry individuals	European(1020)	ALL(1020)	EUR(1020)	ALL(1020)	Periodontal microbiota	HPOID:0000168	Abnormality of the gingiva	DOID:824	periodontitis	D055113	Chronic Periodontitis	NA	NA	Periodontitis	rs1011108-T	Research Support, N.I.H., Extramural	C	OTOF
2	27859317	rs111571364	G	T	rs111571364	24024966	8.00E-06	Age 20-60 years	3.46	[2.01-5.97]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs111571364-T	NA	G	GPN1
2	67282576	rs11676618	G	T	rs11676618	24024966	8.41E-06	Age 20-81 years	1.3	[1.16-1.46]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs11676618-T	NA	T	NA
2	67290263	rs2861317	G	A	rs2861317	24024966	7.63E-06	Age 20-81 years	1.32	[1.17-1.49]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs2861317-A	NA	A	NA
2	67297409	rs1833219	A	C	rs1833219	24024966	8.00E-06	Age 20-81 years	1.32	[1.16-1.49]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	A	NA
2	130023641	rs11681435	G	T	rs11681435	24024966	9.41E-06	Age 20-81 years	1.28	[1.15-1.43]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	G	NA
2	130034326	rs7567687	C	T	rs7567687	24024966	8.00E-06	Age 20-60 years	1.32	[1.18-1.49]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	C	NA
2	130034326	rs7567687	C	T	rs7567687	24024966	8.00E-07	Age 20-81 years	1.32	[1.18-1.47]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	C	NA
2	141226309	rs72899866	T	A	rs72899866	24024966	5.00E-06	Age 20-60 years	1.39	[1.21-1.60]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs72899866-A	NA	T	LRP1B
2	166144414	rs16850317	T	G	rs16850317	24024966	5.00E-06	Age 20-60 years	0.35	[0.20-0.50] unit decrease	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs16850317-T	NA	T	SCN2A
2	176717741	rs9287989	T	C	rs9287989	22699663	4.00E-06	A. actino	1.8	[1.39-2.33]	1,020 European ancestry individuals	European(1020)	ALL(1020)	EUR(1020)	ALL(1020)	Periodontal microbiota	HPOID:0000168	Abnormality of the gingiva	DOID:824	periodontitis	D055113	Chronic Periodontitis	NA	NA	Periodontitis	rs9287989-C	Research Support, N.I.H., Extramural	C	NA
3	4223616	rs2587949	C	G	rs2587949	24024966	8.00E-06	Age 20-81 years	0.14	[0.081-0.206] unit increase	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs2587949-G	NA	G	NA
3	12923197	rs2569991	C	A	rs2569991	24024966	1.00E-06	Age 20-81 years	0.2	[0.12-0.28] unit increase	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs2569991-C	NA	A	NA
3	12954868	rs2600322	A	G	rs2600322	24024966	8.22E-06	Age 20-81 years	0.2	[0.11-0.28] unit decrease	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs2600322-G	NA	C	IQSEC1
3	12963216	rs2600221	C	T	rs2600221	24024966	8.77E-06	Age 20-81 years	0.2	[0.11-0.28] unit decrease	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs2600221-T	NA	A	IQSEC1
3	12963445	rs2252275	T	A	rs2252275	24024966	8.54E-06	Age 20-81 years	0.2	[0.11-0.28] unit increase	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs2252275-T	NA	A	IQSEC1
3	22473729	rs17011371	A	G	rs17011371	24024966	6.00E-06	Age 20-81 years	2.09	[1.52-2.88]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs17011371-A	NA	A	NA
3	31975321	rs11713199	C	G	rs11713199	24347629	6.90E-06	(PD2)	1.87	NA	93 European ancestry cases; 83 European ancestry individuals; 497 European ancestry controls	European(673)	ALL(673)	EUR(673)	ALL(673)	Periodontal disease-related phenotypes	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	Research Support, N.I.H., Extramural	C	OSBPL10
3	31981227	rs12630254	T	C	rs12630254	24347629	6.70E-06	(PD2)	1.9	NA	93 European ancestry cases; 83 European ancestry individuals; 497 European ancestry controls	European(673)	ALL(673)	EUR(673)	ALL(673)	Periodontal disease-related phenotypes	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	Research Support, N.I.H., Extramural	T	OSBPL10
3	31981767	rs12630931	T	C	rs12630931	24347629	6.00E-06	(PD2)	1.89	NA	93 European ancestry cases; 83 European ancestry individuals; 497 European ancestry controls	European(673)	ALL(673)	EUR(673)	ALL(673)	Periodontal disease-related phenotypes	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	Research Support, N.I.H., Extramural	T	OSBPL10
3	34260092	rs145744974	A	G	rs145744974	24024966	4.00E-06	Age 20-60 years	0.29	[0.17-0.42] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs145744974-A	NA	A	NA
3	42799858	rs339678	T	A	rs339678	24024966	8.59E-06	Age 20-81 years	0.4	[0.23-0.58] unit increase	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs339678-T	NA	T	CCDC13
3	42808071	rs339665	C	T	rs339665	24024966	6.00E-06	Age 20-81 years	0.41	[0.23-0.58] unit decrease	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs339665-T	NA	A	CCDC13
3	55563344	rs1875110	T	C	rs1875110	24024966	4.00E-06	Age 20-60 years	0.13	[0.074-0.183] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs1875110-T	NA	T	ERC2
3	76722454	rs197097	G	A	rs197097	24024966	2.66E-06	Age 20-60 years	1.35	[1.19-1.53]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs197097-A	NA	C	ROBO2
3	76722766	rs264537	C	G	rs264537	24024966	3.00E-06	Age 20-60 years	1.35	[1.19-1.54]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs264537-C	NA	G	ROBO2
3	88977897	rs12497795	C	T	rs12497795	24024966	2.00E-06	Age 20-81 years	0.08	[0.046-0.110] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs12497795-T	NA	C	NA
3	122356451	rs78411303	G	A	rs78411303	24024966	3.00E-06	Age 20-60 years	1.96	[1.47-2.56]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	G	NA
3	122366381	rs80157733	C	G	rs80157733	24024966	6.35E-06	Age 20-60 years	1.92	[1.45-2.55]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs80157733-C	NA	C	NA
3	158509830	rs7615751	A	C	rs7615751	24024966	1.94E-06	Age 20-60 years	1.33	[1.18-1.50]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs7615751-A	NA	C	NA
3	158512381	rs9822005	G	A	rs9822005	24024966	2.17E-06	Age 20-60 years	1.33	[1.18-1.49]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	A	NA
3	158512381	rs9822005	G	A	rs9822005	24024966	3.65E-06	Age 20-60 years	1.32	[1.18-1.49]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	A	NA
3	158514360	rs6802315	T	A	rs6802315	24024966	3.00E-07	Age 20-60 years	1.37	[1.20-1.54]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	A	NA
3	173180633	rs11709498	A	C	rs11709498	24024966	6.00E-06	Age 20-81 years	0.15	[0.089-0.221] unit decrease	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs11709498-C	NA	A	NLGN1
4	13242797	rs733048	G	A	rs733048	24347629	1.00E-06	(PD1)	2.4	NA	93 European ancestry cases; 83 European ancestry individuals; 497 European ancestry controls	European(673)	ALL(673)	EUR(673)	ALL(673)	Periodontal disease-related phenotypes	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	Research Support, N.I.H., Extramural	G	NA
4	13242797	rs733048	G	A	rs733048	24347629	4.00E-06	(PD2)	1.95	NA	93 European ancestry cases; 83 European ancestry individuals; 497 European ancestry controls	European(673)	ALL(673)	EUR(673)	ALL(673)	Periodontal disease-related phenotypes	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	Research Support, N.I.H., Extramural	G	NA
4	26795603	rs4572866	T	C	rs4572866	25008200	5.80E-05	NA	NA	NA	63 European ancestry cases; 543 European ancestry controls; up to 32 African American cases; up to 158 African American controls; up to 4 cases; up to 66 controls	NOPOP(70)	African American(190)	European(606)	ALL(866)	NOPOP(70)	AFR(190)	EUR(606)	ALL(866)	Periodontitis (Chronic)	NA	NA	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis
4	37938518	rs10010758	T	C	rs10010758	22699663	4.00E-06	Red	1.91	[1.45-2.51]	1,020 European ancestry individuals	European(1020)	ALL(1020)	EUR(1020)	ALL(1020)	Periodontal microbiota	HPOID:0000168	Abnormality of the gingiva	DOID:824	periodontitis	D055113	Chronic Periodontitis	NA	NA	Periodontitis	rs10010758-C	Research Support, N.I.H., Extramural	T	TBC1D1
4	162246075	rs2218426	A	G	rs2218426	24024966	9.82E-06	Age 20-60 years	0.2	[0.11-0.29] unit increase	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs2218426-G	NA	A	NA
4	162246176	rs17335892	C	T	rs17335892	24024966	9.82E-06	Age 20-60 years	0.2	[0.11-0.29] unit increase	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs17335892-T	NA	C	NA
4	190538063	rs13145041	A	C,G	rs13145041	24024966	7.00E-07	Age 20-60 years	1.65	[1.35-2.00]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs13145041-A	NA	A,C	NA
4	190538063	rs34600205	A	AG	rs13145041	24024966	7.00E-07	Age 20-60 years	1.65	[1.35-2.00]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs13145041-A	NA	A,C	NA
4	190551954	rs11724073	C	T	rs11724073	24024966	6.27E-06	Age 20-60 years	1.37	[1.19-1.56]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	C	NA
4	190562142	rs9990436	A	C	rs9990436	24024966	7.64E-06	Age 20-60 years	1.36	[1.19-1.56]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs9990436-A	NA	A,C	NA
5	98575406	rs6863194	C	G	rs6863194	24024966	9.88E-06	Age 20-81 years	0.05	[0.03-0.08] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs6863194-C	NA	G	NA
5	98593453	rs1500251	G	A	rs1500251	24024966	9.00E-06	Age 20-81 years	0.05	[0.031-0.078] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs1500251-A	NA	A	NA
5	110498972	rs17132862	G	A	rs17132862	24024966	1.82E-06	Age 20-60 years	2.19	[1.59-3.02]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs17132862-A	NA	G	NA
5	110502429	rs17132883	C	T	rs17132883	24024966	2.00E-06	Age 20-60 years	2.19	[1.59-3.01]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs17132883-T	NA	C	NA
5	110521329	rs10056568	T	G	rs10056568	24024966	1.04E-06	Age 20-60 years	2.17	[1.59-2.94]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	T	NA
5	110522803	rs17132909	G	A	rs17132909	24024966	1.21E-06	Age 20-60 years	2.18	[1.59-2.98]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs17132909-A	NA	G	NA
5	110533593	rs10071052	T	A	rs10071052	24024966	8.60E-07	Age 20-60 years	2.2	NA	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs10071052-A	NA	T	NA
5	110533968	rs11953602	G	C	rs11953602	24024966	8.60E-07	Age 20-60 years	2.2	NA	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs11953602-C	NA	C	NA
5	110535029	rs10055755	G	A	rs10055755	24024966	8.60E-07	Age 20-60 years	2.2	NA	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs10055755-A	NA	G	NA
5	110536663	rs13360546	A	G	rs13360546	24024966	8.68E-07	Age 20-60 years	2.17	[1.61-3.03]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	A	NA
5	110536795	rs13358530	T	C	rs13358530	24024966	8.69E-07	Age 20-60 years	2.17	[1.61-3.03]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	T	NA
5	110537597	rs9326830	G	C	rs9326830	24024966	8.58E-07	Age 20-60 years	2.2	[1.61-3.01]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs9326830-C	NA	G	NA
5	110539349	rs1370966	G	A	rs1370966	24024966	8.56E-07	Age 20-60 years	2.21	[1.61-3.02]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs1370966-A	NA	A,G	NA
5	110539392	rs1370967	G	A	rs1370967	24024966	8.00E-07	Age 20-60 years	2.21	[1.61-3.02]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs1370967-A	NA	G	NA
5	110540436	rs763439	C	T	rs763439	24024966	9.29E-07	Age 20-60 years	2.19	NA	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs763439-T	NA	C	NA
5	110540525	rs763440	C	T	rs763440	24024966	8.62E-07	Age 20-60 years	2.21	[1.61-3.02]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs763440-T	NA	C	NA
5	110547418	rs957924	G	A	rs957924	24024966	7.87E-07	Age 20-60 years	2.22	[1.62-3.04]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs957924-A	NA	C	NA
5	116513164	rs7706447	A	C	rs7706447	24024966	7.13E-06	Age 20-81 years	0.3	[0.17-0.42] unit increase	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs7706447-C	NA	A	NA
5	116513605	rs12153048	C	G	rs12153048	24024966	2.00E-06	Age 20-81 years	0.34	[0.20-0.48] unit increase	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs12153048-G	NA	C	NA
5	116513605	rs12153048	C	G	rs12153048	24024966	6.00E-06	Age 20-60 years	0.35	[0.20-0.49] unit increase	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs12153048-G	NA	C	NA
5	147805120	rs10043775	T	C	rs10043775	22699663	2.00E-06	Red	2.06	[1.51-2.83]	1,020 European ancestry individuals	European(1020)	ALL(1020)	EUR(1020)	ALL(1020)	Periodontal microbiota	HPOID:0000168	Abnormality of the gingiva	DOID:824	periodontitis	D055113	Chronic Periodontitis	NA	NA	Periodontitis	rs10043775-T	Research Support, N.I.H., Extramural	C	FBXO38
5	151566652	rs211496	C	T	rs211496	24024966	5.56E-06	Age 20-81 years	1.3	[1.16-1.45]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	A	NA
5	151568099	rs294958	A	G	rs294958	24024966	5.00E-06	Age 20-81 years	1.29	[1.16-1.44]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs294958-A	NA	C	NA
5	151569417	rs294945	C	A	rs294945	24024966	6.42E-06	Age 20-81 years	1.28	[1.15-1.43]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	A	NA
5	151572805	rs2434975	T	C	rs2434975	24024966	5.35E-06	Age 20-81 years	1.29	[1.16-1.44]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs2434975-T	NA	C	NA
5	151575731	rs1156008	T	C	rs1156008	24024966	9.19E-06	Age 20-81 years	1.28	[1.15-1.43]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs1156008-T	NA	C	NA
5	151576313	rs167169	T	C	rs167169	24024966	5.36E-06	Age 20-81 years	1.29	[1.16-1.44]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs167169-T	NA	G	NA
5	151579579	rs2434976	G	A	rs2434976	24024966	6.02E-06	Age 20-81 years	1.28	[1.15-1.43]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	A	NA
5	151580934	rs169819	A	T	rs169819	24024966	6.11E-06	Age 20-81 years	1.29	[1.15-1.44]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs169819-A	NA	T	NA
5	167643545	rs6885116	A	G	rs6885116	22699663	1.00E-06	A. actino	2.57	[1.76-3.74]	1,020 European ancestry individuals	European(1020)	ALL(1020)	EUR(1020)	ALL(1020)	Periodontal microbiota	HPOID:0000168	Abnormality of the gingiva	DOID:824	periodontitis	D055113	Chronic Periodontitis	NA	NA	Periodontitis	rs6885116-G	Research Support, N.I.H., Extramural	G	ODZ2
5	172292306	rs6890783	G	A	rs6890783	24024966	5.00E-06	Age 20-60 years	6.45	[2.89-14.38]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs6890783-A	NA	G	ERGIC1
6	21503218	rs6456431	A	G	rs6456431	24024966	9.95E-06	Age 20-81 years	0.15	[0.08-0.22] unit decrease	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs6456431-G	NA	G	NA
6	24062788	rs146696563	T	C	rs146696563	24024966	4.00E-06	Age 20-60 years	0.24	[0.14-0.34] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs146696563-T	NA	T	NA
6	32972404	rs3128935	T	C	rs3128935	24024966	9.00E-06	Age 20-60 years	2.28	[1.59-3.28]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs3128935-T	NA	T	HLA-DOA
6	41379315	rs7762544	G	A	rs7762544	23459936	8.00E-08	Moderate CPd	1.4	[1.24-1.59]	4,504 European ancestry individuals	European(4504)	ALL(4504)	EUR(4504)	ALL(4504)	Periodontitis	HPOID:0000704	Periodontitis	DOID:824	periodontitis	D010518	Periodontitis	EFOID:0000649	periodontitis	Periodontitis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
6	45696788	rs1932040	A	G	rs1932040	22699663	1.00E-06	Orange	2.47	[1.67-3.65]	1,020 European ancestry individuals	European(1020)	ALL(1020)	EUR(1020)	ALL(1020)	Periodontal microbiota	HPOID:0000168	Abnormality of the gingiva	DOID:824	periodontitis	D055113	Chronic Periodontitis	NA	NA	Periodontitis	rs1932040-G	Research Support, N.I.H., Extramural	T	NA
6	99555756	rs6905786	A	G	rs6905786	25008200	1.41E-05	NA	NA	NA	63 European ancestry cases; 543 European ancestry controls; up to 32 African American cases; up to 158 African American controls; up to 4 cases; up to 66 controls	NOPOP(70)	African American(190)	European(606)	ALL(866)	NOPOP(70)	AFR(190)	EUR(606)	ALL(866)	Periodontitis (Chronic)	NA	NA	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis
6	106831666	rs7740539	T	C	rs7740539	25008200	1.39E-05	NA	NA	NA	63 European ancestry cases; 543 European ancestry controls; up to 32 African American cases; up to 158 African American controls; up to 4 cases; up to 66 controls	NOPOP(70)	African American(190)	European(606)	ALL(866)	NOPOP(70)	AFR(190)	EUR(606)	ALL(866)	Periodontitis (Chronic)	NA	NA	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis
6	124405155	rs13204086	C	T	rs13204086	24024966	2.00E-06	Age 20-81 years	0.16	[0.095-0.228] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs13204086-T	NA	C	NKAIN2
6	124437412	rs13220639	C	T	rs13220639	24024966	1.32E-06	Age 20-60 years	0.15	[0.09-0.21] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs13220639-T	NA	C	NKAIN2
6	124439410	rs35900954	G	A	rs35900954	24024966	1.09E-06	Age 20-60 years	0.15	[0.09-0.21] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs35900954-A	NA	G	NKAIN2
6	124559732	rs77490164	C	T	rs77490164	24024966	8.00E-07	Age 20-60 years	0.13	[0.077-0.179] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs77490164-T	NA	C	NKAIN2
6	129872966	rs10457525	G	T	rs10457525	24347629	3.50E-06	(PD1)	2.33	NA	93 European ancestry cases; 83 European ancestry individuals; 497 European ancestry controls	European(673)	ALL(673)	EUR(673)	ALL(673)	Periodontal disease-related phenotypes	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	Research Support, N.I.H., Extramural	T	NA
6	129874355	rs7749983	T	A	rs7749983	24347629	2.00E-06	(PD1)	2.39	NA	93 European ancestry cases; 83 European ancestry individuals; 497 European ancestry controls	European(673)	ALL(673)	EUR(673)	ALL(673)	Periodontal disease-related phenotypes	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	Research Support, N.I.H., Extramural	T	NA
6	129896501	rs10457526	G	T	rs10457526	24347629	6.00E-06	(PD1)	2.26	NA	93 European ancestry cases; 83 European ancestry individuals; 497 European ancestry controls	European(673)	ALL(673)	EUR(673)	ALL(673)	Periodontal disease-related phenotypes	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	Research Support, N.I.H., Extramural	G	NA
6	151645078	rs2297778	A	G	rs2297778	24347629	9.70E-06	(PD2)	2.32	NA	93 European ancestry cases; 83 European ancestry individuals; 497 European ancestry controls	European(673)	ALL(673)	EUR(673)	ALL(673)	Periodontal disease-related phenotypes	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	Research Support, N.I.H., Extramural	T	AKAP12
6	160459191	rs78797168	A	G	rs78797168	24024966	2.00E-06	Age 20-60 years	1.75	[1.39-2.22]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs78797168-A	NA	A	IGF2R
7	8957041	rs10266202	C	T	rs10266202	25008200	3.89E-05	NA	NA	NA	63 European ancestry cases; 543 European ancestry controls; up to 32 African American cases; up to 158 African American controls; up to 4 cases; up to 66 controls	NOPOP(70)	African American(190)	European(606)	ALL(866)	NOPOP(70)	AFR(190)	EUR(606)	ALL(866)	Periodontitis (Chronic)	NA	NA	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis
7	22994186	rs73082373	T	G	rs73082373	24024966	6.00E-06	Age 20-60 years	0.13	[0.071-0.181] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs73082373-T	NA	T	FAM126A
7	24378040	rs2521634	G	A	rs2521634	23459936	4.00E-07	Severe CPd	1.49	[1.28-1.73]	4,504 European ancestry individuals	European(4504)	ALL(4504)	EUR(4504)	ALL(4504)	Periodontitis	HPOID:0000704	Periodontitis	DOID:824	periodontitis	D010518	Periodontitis	EFOID:0000649	periodontitis	Periodontitis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
7	135501469	rs13237474	C	T	rs13237474	24024966	2.00E-07	Age 20-60 years	3.05	[2.00-4.65]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs13237474-T	NA	T	NA
8	3076959	rs28455997	T	C	rs28455997	24024966	3.00E-06	Age 20-60 years	1.48	[1.26-1.75]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs28455997-T	NA	T	CSMD1
8	3081727	rs55737375	C	T	rs55737375	24024966	6.98E-06	Age 20-60 years	1.43	[1.22-1.69]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	C	CSMD1
8	3082687	rs10091165	C	A	rs10091165	24024966	8.24E-06	Age 20-60 years	1.43	[1.22-1.69]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	C	CSMD1
8	3088763	rs1540507	C	T	rs1540507	24024966	9.00E-06	Age 20-81 years	1.47	[1.23-1.75]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	T	CSMD1
8	3088862	rs1540508	C	G	rs1540508	24024966	9.34E-06	Age 20-81 years	1.47	[1.24-1.74]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs1540508-C	NA	G	CSMD1
8	3088938	rs1540509	C	G	rs1540509	24024966	9.37E-06	Age 20-81 years	1.47	[1.24-1.74]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs1540509-C	NA	C	CSMD1
8	6821617	rs2738058	T	C	rs2738058	24024966	6.00E-06	Age 20-81 years	1.29	[1.16-1.45]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs2738058-T	NA	G	NA
8	6821617	rs2738058	T	C	rs2738058	24024966	7.00E-06	Age 20-60 years	1.33	[1.18-1.51]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs2738058-T	NA	G	NA
8	11480457	rs2243407	T	C	rs2243407	24024966	6.00E-06	Age 20-60 years	1.33	[1.18-1.52]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	T	NA
8	11480457	rs2243407	T	C	rs2243407	24024966	9.00E-06	Age 20-81 years	1.3	[1.16-1.47]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	T	NA
8	63598350	rs16929397	G	T	rs16929397	24024966	9.65E-06	Age 20-60 years	1.56	[1.28-1.90]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs16929397-T	NA	G	NKAIN3
8	63617113	rs931131	A	G	rs931131	24024966	7.50E-06	Age 20-60 years	1.56	[1.28-1.90]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs931131-A	NA	G	NKAIN3
8	63621550	rs2882925	T	G	rs2882925	24024966	7.46E-06	Age 20-60 years	1.56	[1.28-1.90]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs2882925-T	NA	T	NKAIN3
8	63621569	rs2882926	A	T	rs2882926	24024966	7.00E-06	Age 20-60 years	1.56	[1.28-1.90]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs2882926-A	NA	A	NKAIN3
8	63625756	rs7008492	G	C	rs7008492	24024966	7.48E-06	Age 20-60 years	1.56	[1.28-1.89]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	C	NKAIN3
8	63630969	rs4737611	C	T	rs4737611	24024966	7.53E-06	Age 20-60 years	1.56	[1.28-1.89]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	T	NKAIN3
8	63649211	rs1600537	A	C	rs1600537	24024966	9.57E-06	Age 20-60 years	1.55	[1.28-1.89]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs1600537-A	NA	C	NKAIN3
8	63650049	rs6996317	T	A	rs6996317	24024966	9.78E-06	Age 20-60 years	1.56	[1.28-1.89]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	A	NKAIN3
8	63695919	rs12708012	T	C	rs12708012	24024966	9.99E-06	Age 20-60 years	1.56	[1.28-1.90]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs12708012-T	NA	C	NKAIN3
8	105700583	rs4734805	T	C	rs4734805	24024966	6.19E-06	Age 20-60 years	0.21	[0.12-0.3] unit increase	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs4734805-T	NA	T	NA
8	105700680	rs4734806	A	G	rs4734806	24024966	6.00E-06	Age 20-60 years	0.21	[0.12-0.30] unit decrease	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs4734806-G	NA	A	NA
8	105713240	rs36072167	T	C	rs36072167	24024966	9.85E-06	Age 20-60 years	0.2	[0.11-0.29] unit decrease	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs36072167-C	NA	T	NA
8	110020230	rs4735081	T	C	rs4735081	25008200	1.80E-05	NA	NA	NA	63 European ancestry cases; 543 European ancestry controls; up to 32 African American cases; up to 158 African American controls; up to 4 cases; up to 66 controls	NOPOP(70)	African American(190)	European(606)	ALL(866)	NOPOP(70)	AFR(190)	EUR(606)	ALL(866)	Periodontitis (Chronic)	NA	NA	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis
8	115121027	rs9942773	A	C	rs9942773	22699663	2.00E-06	Orange	2.07	[1.51-2.82]	1,020 European ancestry individuals	European(1020)	ALL(1020)	EUR(1020)	ALL(1020)	Periodontal microbiota	HPOID:0000168	Abnormality of the gingiva	DOID:824	periodontitis	D055113	Chronic Periodontitis	NA	NA	Periodontitis	rs9942773-A	Research Support, N.I.H., Extramural	C	NA
8	122207956	rs11401596	A	AT	rs11401596	24024966	7.00E-06	Age 20-60 years	1.3	[1.16-1.45]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	A	NA
8	122207956	rs397711003	A	AT	rs11401596	24024966	7.00E-06	Age 20-60 years	1.3	[1.16-1.45]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	A	NA
8	122207956	rs397830377	A	AT	rs11401596	24024966	7.00E-06	Age 20-60 years	1.3	[1.16-1.45]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	A	NA
8	122208658	rs2386229	G	A	rs2386229	24024966	3.80E-06	Age 20-60 years	1.32	[1.18-1.47]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	C	NA
8	122209249	rs13271594	A	G	rs13271594	24024966	4.54E-06	Age 20-60 years	1.31	[1.17-1.47]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs13271594-A	NA	A	NA
8	122209249	rs13271594	A	G	rs13271594	24024966	8.28E-06	Age 20-60 years	1.3	[1.16-1.46]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs13271594-A	NA	A	NA
8	122210890	rs7819988	T	C	rs7819988	24024966	3.00E-06	Age 20-60 years	1.32	[1.17-1.48]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs7819988-T	NA	T	NA
8	122212386	rs7815968	C	G	rs7815968	24024966	8.45E-06	Age 20-60 years	1.3	[1.16-1.46]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs7815968-C	NA	C	NA
8	122212869	rs527469349	TA	T	rs7838368	24024966	3.25E-06	Age 20-60 years	1.32	[1.18-1.47]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	T	NA
8	122212869	rs7838368	T	A	rs7838368	24024966	3.25E-06	Age 20-60 years	1.32	[1.18-1.47]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	T	NA
8	122215915	rs7818568	T	G	rs7818568	24024966	8.71E-06	Age 20-60 years	1.3	[1.16-1.45]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs7818568-T	NA	G	NA
8	122696143	rs7816221	G	A	rs7816221	24347629	9.20E-06	(PD1)	2.12	NA	93 European ancestry cases; 83 European ancestry individuals; 497 European ancestry controls	European(673)	ALL(673)	EUR(673)	ALL(673)	Periodontal disease-related phenotypes	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	Research Support, N.I.H., Extramural	A	NA
8	122697132	rs3870371	C	A	rs3870371	24347629	6.00E-06	(PD1)	2.15	NA	93 European ancestry cases; 83 European ancestry individuals; 497 European ancestry controls	European(673)	ALL(673)	EUR(673)	ALL(673)	Periodontal disease-related phenotypes	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	Research Support, N.I.H., Extramural	A	NA
8	122700197	rs200345796	AT	A	rs920455	24347629	9.20E-06	(PD1)	2.11	NA	93 European ancestry cases; 83 European ancestry individuals; 497 European ancestry controls	European(673)	ALL(673)	EUR(673)	ALL(673)	Periodontal disease-related phenotypes	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	Research Support, N.I.H., Extramural	G	NA
8	122700197	rs920455	A	G	rs920455	24347629	9.20E-06	(PD1)	2.11	NA	93 European ancestry cases; 83 European ancestry individuals; 497 European ancestry controls	European(673)	ALL(673)	EUR(673)	ALL(673)	Periodontal disease-related phenotypes	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	Research Support, N.I.H., Extramural	G	NA
8	139301378	rs10875423	T	A	rs10875423	24024966	9.00E-06	Age 20-81 years	1.43	[1.22-1.67]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	T	FAM135B
8	142653435	rs6578205	A	T	rs6578205	24024966	9.59E-06	Age 20-60 years	3.51	[2.01-6.12]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs6578205-A	NA	T	NA
9	969688	rs10977870	G	C	rs10977870	24024966	9.66E-06	Age 20-60 years	0.18	[0.1-0.26] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs10977870-C	NA	G	NA
9	6486308	rs16924631	G	C	rs16924631	22699663	3.00E-06	Red	2.29	[1.61-3.24]	1,020 European ancestry individuals	European(1020)	ALL(1020)	EUR(1020)	ALL(1020)	Periodontal microbiota	HPOID:0000168	Abnormality of the gingiva	DOID:824	periodontitis	D055113	Chronic Periodontitis	NA	NA	Periodontitis	rs16924631-C	Research Support, N.I.H., Extramural	G	UHRF2
9	12914396	rs1953021	G	T	rs1953021	24024966	1.00E-06	Age 20-81 years	1.35	[1.20-1.53]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs1953021-T	NA	T	NA
9	107677289	rs4149263	A	G	rs4149263	24024966	7.00E-06	Age 20-81 years	0.06	[0.032-0.080] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs4149263-A	NA	T	ABCA1
9	124565820	rs10760187	T	C	rs10760187	22699663	5.00E-07	P. gingi	2.07	[1.55-2.76]	1,020 European ancestry individuals	European(1020)	ALL(1020)	EUR(1020)	ALL(1020)	Periodontal microbiota	HPOID:0000168	Abnormality of the gingiva	DOID:824	periodontitis	D055113	Chronic Periodontitis	NA	NA	Periodontitis	rs10760187-C	Research Support, N.I.H., Extramural	C	NA
9	134791779	rs6597536	C	T	rs6597536	25008200	3.62E-05	NA	NA	NA	63 European ancestry cases; 543 European ancestry controls; up to 32 African American cases; up to 158 African American controls; up to 4 cases; up to 66 controls	NOPOP(70)	African American(190)	European(606)	ALL(866)	NOPOP(70)	AFR(190)	EUR(606)	ALL(866)	Periodontitis (Chronic)	NA	NA	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis
9	138529722	rs1537415	G	C	rs1537415	19897590	6.00E-09	NA	1.59	[1.36-1.86]	283 German cases; 972 German controls	German(1255)	ALL(1255)	EUR(1255)	ALL(1255)	Periodontitis	HPOID:0000704	Periodontitis	DOID:824	periodontitis	D010518	Periodontitis	EFOID:0000649	periodontitis	Periodontitis	rs1537415-G	Research Support, Non-U.S. Gov't	G	GLT6D1
10	15600671	rs28643277	C	A	rs28643277	24024966	9.00E-06	Age 20-60 years	1.32	[1.17-1.50]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs28643277-A	NA	A	ITGA8
10	36885921	rs1360573	A	G	rs1360573	22699663	2.00E-06	P. gingi	2.75	[1.78-4.26]	1,020 European ancestry individuals	European(1020)	ALL(1020)	EUR(1020)	ALL(1020)	Periodontal microbiota	HPOID:0000168	Abnormality of the gingiva	DOID:824	periodontitis	D055113	Chronic Periodontitis	NA	NA	Periodontitis	rs1360573-A	Research Support, N.I.H., Extramural	A	NA
10	54125312	rs146295628	G	T	rs146295628	24024966	9.40E-06	Age 20-60 years	0.1	[0.06-0.15] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs146295628-T	NA	G	NA
10	54130753	rs112125027	A	G	rs112125027	24024966	5.00E-06	Age 20-60 years	0.1	[0.060-0.149] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs112125027-A	NA	A	NA
10	54133021	rs138374901	G	T	rs138374901	24024966	4.75E-06	Age 20-60 years	0.1	[0.06-0.15] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs138374901-T	NA	G	NA
10	87634924	rs1970525	C	G	rs1970525	22699663	4.00E-06	A. actino	2.89	[1.85-4.52]	1,020 European ancestry individuals	European(1020)	ALL(1020)	EUR(1020)	ALL(1020)	Periodontal microbiota	HPOID:0000168	Abnormality of the gingiva	DOID:824	periodontitis	D055113	Chronic Periodontitis	NA	NA	Periodontitis	rs1970525-G	Research Support, N.I.H., Extramural	G	GRID1
10	89752211	rs149784093	C	T	rs149784093	24024966	3.00E-06	Age 20-60 years	0.22	[0.13-0.32] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs149784093-T	NA	C	NA
10	112452132	rs1954179	A	G	rs1954179	25008200	7.42E-05	NA	NA	NA	63 European ancestry cases; 543 European ancestry controls; up to 32 African American cases; up to 158 African American controls; up to 4 cases; up to 66 controls	NOPOP(70)	African American(190)	European(606)	ALL(866)	NOPOP(70)	AFR(190)	EUR(606)	ALL(866)	Periodontitis (Chronic)	NA	NA	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis
10	124887125	rs61862032	T	C	rs61862032	24024966	9.00E-06	Age 20-60 years	0.2	[0.11-0.28] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs61862032-T	NA	T	NA
10	134295815	rs73389468	C	T	rs73389468	24024966	9.00E-06	Age 20-60 years	2.78	[1.75-4.35]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	C	NA
11	6750057	rs12799172	C	T	rs12799172	24347629	5.00E-06	(PD1)	2.12	NA	93 European ancestry cases; 83 European ancestry individuals; 497 European ancestry controls	European(673)	ALL(673)	EUR(673)	ALL(673)	Periodontal disease-related phenotypes	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	Research Support, N.I.H., Extramural	C	NA
11	30489027	rs1026477	G	A	rs1026477	25008200	5.48E-05	NA	NA	NA	63 European ancestry cases; 543 European ancestry controls; up to 32 African American cases; up to 158 African American controls; up to 4 cases; up to 66 controls	NOPOP(70)	African American(190)	European(606)	ALL(866)	NOPOP(70)	AFR(190)	EUR(606)	ALL(866)	Periodontitis (Chronic)	NA	NA	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis
11	84247123	rs10501568	A	G	rs10501568	25008200	3.00E-06	NA	NA	NA	63 European ancestry cases; 543 European ancestry controls; up to 32 African American cases; up to 158 African American controls; up to 4 cases; up to 66 controls	NOPOP(70)	African American(190)	European(606)	ALL(866)	NOPOP(70)	AFR(190)	EUR(606)	ALL(866)	Periodontitis (Chronic)	NA	NA	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis
11	130529219	rs12792526	A	G	rs12792526	24024966	3.00E-06	Age 20-81 years	0.2	[0.12-0.29] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs12792526-A	NA	A	NA
11	130529219	rs12792526	A	G	rs12792526	24024966	4.00E-06	Age 20-60 years	0.22	[0.13-0.31] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs12792526-A	NA	A	NA
12	11558877	rs71455379	C	G	rs71455379	24024966	9.00E-06	Age 20-60 years	1.89	[1.43-2.50]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	NA	NA
12	60037770	rs982322	T	G	rs982322	25008200	3.99E-05	NA	NA	NA	63 European ancestry cases; 543 European ancestry controls; up to 32 African American cases; up to 158 African American controls; up to 4 cases; up to 66 controls	NOPOP(70)	African American(190)	European(606)	ALL(866)	NOPOP(70)	AFR(190)	EUR(606)	ALL(866)	Periodontitis (Chronic)	NA	NA	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis
12	92987208	rs11829373	G	C	rs11829373	24024966	7.00E-06	Age 20-60 years	0.08	[0.045-0.115] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs11829373-C	NA	G	NA
13	104721789	rs1913208	T	G	rs1913208	25008200	6.46E-05	NA	NA	NA	63 European ancestry cases; 543 European ancestry controls; up to 32 African American cases; up to 158 African American controls; up to 4 cases; up to 66 controls	NOPOP(70)	African American(190)	European(606)	ALL(866)	NOPOP(70)	AFR(190)	EUR(606)	ALL(866)	Periodontitis (Chronic)	NA	NA	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis
13	106067920	rs17655948	T	A	rs17655948	24024966	7.00E-06	Age 20-60 years	0.16	[0.093-0.234] unit increase	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs17655948-T	NA	T	NA
14	38046611	rs59290731	C	A	rs59290731	24024966	7.33E-06	Age 20-60 years	2.7	[1.75-4.17]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	C	NA
14	38062732	rs72674251	T	C	rs72674251	24024966	8.23E-06	Age 20-60 years	2.68	[1.74-4.13]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs72674251-T	NA	T	FOXA1
14	38065020	rs76470659	G	A	rs76470659	24024966	7.81E-06	Age 20-60 years	2.7	[1.75-4.17]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	G	NA
14	38066548	rs2181180	C	T	rs2181180	24024966	7.53E-06	Age 20-60 years	2.7	[1.75-4.17]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	C	NA
14	38066575	rs12587630	A	G	rs12587630	24024966	7.00E-06	Age 20-60 years	2.69	[1.75-4.15]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs12587630-A	NA	A	NA
14	38067315	rs34249416	T	A	rs34249416	24024966	7.47E-06	Age 20-60 years	2.7	[1.75-4.17]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	T	NA
14	50856641	rs3783412	A	G	rs3783412	24347629	8.00E-06	(PD2)	1.85	NA	93 European ancestry cases; 83 European ancestry individuals; 497 European ancestry controls	European(673)	ALL(673)	EUR(673)	ALL(673)	Periodontal disease-related phenotypes	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	Research Support, N.I.H., Extramural	T	CDKL1
14	69360631	rs12050161	T	C	rs12050161	24024966	4.00E-06	Age 20-60 years	0.07	[0.040-0.100] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs12050161-T	NA	T	ACTN1
14	75814028	rs11621969	T	C	rs11621969	22699663	9.00E-07	A. actino	2.46	[1.68-3.62]	1,020 European ancestry individuals	European(1020)	ALL(1020)	EUR(1020)	ALL(1020)	Periodontal microbiota	HPOID:0000168	Abnormality of the gingiva	DOID:824	periodontitis	D055113	Chronic Periodontitis	NA	NA	Periodontitis	rs11621969-T	Research Support, N.I.H., Extramural	T	NA
14	82299173	rs12589327	A	T	rs12589327	24347629	7.00E-06	(PD2)	2.13	NA	93 European ancestry cases; 83 European ancestry individuals; 497 European ancestry controls	European(673)	ALL(673)	EUR(673)	ALL(673)	Periodontal disease-related phenotypes	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	Research Support, N.I.H., Extramural	T	NA
15	24924663	rs12902137	T	C	rs12902137	24024966	6.00E-06	Age 20-60 years	0.18	[0.10-0.26] unit decrease	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs12902137-T	NA	C	C15orf2
15	24999291	rs11858016	G	A	rs11858016	24024966	7.67E-06	Age 20-81 years	0.19	[0.11-0.28] unit increase	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs11858016-G	NA	NA	NA
15	25022988	rs8030136	C	T	rs8030136	24024966	6.00E-06	Age 20-81 years	0.19	[0.11-0.28] unit decrease	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs8030136-T	NA	C	NA
15	33597076	rs2676071	C	T	rs2676071	24024966	7.00E-06	Age 20-81 years	0.04	[0.025-0.064] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs2676071-T	NA	T	NA
15	71574799	rs9806183	G	A,C	rs9806183	24024966	2.00E-06	Age 20-60 years	1.37	[1.20-1.57]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs9806183-C	NA	G	THSD4
15	71574799	rs9806183	G	A,C	rs9806183	24024966	8.25E-06	Age 20-81 years	1.3	[1.16-1.47]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs9806183-C	NA	G	THSD4
15	71576304	rs1442781	C	G	rs1442781	24024966	5.86E-06	Age 20-60 years	1.37	[1.19-1.59]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	G	THSD4
15	71576755	rs1442779	A	G	rs1442779	24024966	3.27E-06	Age 20-60 years	1.39	[1.20-1.61]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	C	THSD4
15	71576755	rs1442779	A	G	rs1442779	24024966	7.00E-06	Age 20-60 years	0.05	[0.031-0.078] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs1442779-A	NA	C	THSD4
15	71576755	rs1442779	A	G	rs1442779	24024966	7.00E-06	Age 20-81 years	1.33	[1.18-1.52]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	C	THSD4
15	71577615	rs12913078	G	A	rs12913078	24024966	4.89E-06	Age 20-60 years	1.39	[1.20-1.59]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs12913078-A	NA	A	THSD4
15	71583413	rs2063826	T	C	rs2063826	24024966	5.70E-06	Age 20-60 years	1.36	[1.19-1.55]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs2063826-T	NA	T	THSD4
15	80192975	rs36035742	C	T	rs36035742	24024966	4.00E-06	Age 20-60 years	0.12	[0.072-0.176] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs36035742-T	NA	C	ST20
15	80219593	rs75598935	G	A	rs75598935	24024966	6.00E-06	Age 20-60 years	0.17	[0.098-0.246] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs75598935-A	NA	C	NA
15	85187245	rs34069323	T	C	rs34069323	24024966	2.00E-06	Age 20-60 years	6.25	[2.94-14.29]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	T	WDR73
15	93713666	rs6497031	G	A	rs6497031	24024966	5.00E-06	Age 20-60 years	1.84	[1.41-2.39]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs6497031-A	NA	A	NA
16	7139173	rs11866781	T	C	rs11866781	24024966	5.00E-06	Age 20-81 years	1.3	[1.16-1.45]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	T	RBFOX1
16	73423202	rs1477403	G	A	rs1477403	25008200	6.18E-05	NA	NA	NA	63 European ancestry cases; 543 European ancestry controls; up to 32 African American cases; up to 158 African American controls; up to 4 cases; up to 66 controls	NOPOP(70)	African American(190)	European(606)	ALL(866)	NOPOP(70)	AFR(190)	EUR(606)	ALL(866)	Periodontitis (Chronic)	NA	NA	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis
16	83783828	rs149740259	G	A	rs149740259	24024966	9.00E-06	Age 20-60 years	0.24	[0.14-0.35] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs149740259-A	NA	G	CDH13
17	62600935	rs111854052	A	T	rs111854052	24024966	9.00E-06	Age 20-60 years	0.32	[0.18-0.47] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs111854052-A	NA	A	SMURF2
17	66364804	rs1558878	T	C	rs1558878	25008200	8.53E-05	NA	NA	NA	63 European ancestry cases; 543 European ancestry controls; up to 32 African American cases; up to 158 African American controls; up to 4 cases; up to 66 controls	NOPOP(70)	African American(190)	European(606)	ALL(866)	NOPOP(70)	AFR(190)	EUR(606)	ALL(866)	Periodontitis (Chronic)	NA	NA	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis
17	68108417	rs12936361	T	C	rs12936361	24024966	5.00E-06	Age 20-60 years	0.23	[0.13-0.33] unit increase	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs12936361-T	NA	T	KCNJ16
17	76219945	rs17879146	T	G	rs17879146	24024966	1.00E-06	Age 20-60 years	0.25	[0.15-0.36] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs17879146-T	NA	T	BIRC5
17	76870581	rs2009196	C	G	rs2009196	24024966	2.00E-06	Age 20-81 years	1.41	[1.22-1.62]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs2009196-C	NA	G	TIMP2
17	77766621	rs8066940	G	A	rs8066940	25008200	2.79E-05	NA	NA	NA	63 European ancestry cases; 543 European ancestry controls; up to 32 African American cases; up to 158 African American controls; up to 4 cases; up to 66 controls	NOPOP(70)	African American(190)	European(606)	ALL(866)	NOPOP(70)	AFR(190)	EUR(606)	ALL(866)	Periodontitis (Chronic)	NA	NA	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis
18	100134	rs74778902	C	T	rs74778902	24024966	7.24E-06	Age 20-60 years	0.2	[0.11-0.29] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs74778902-T	NA	NA	NA
18	120296	rs57440971	C	T	rs57440971	24024966	4.00E-06	Age 20-60 years	0.14	[0.082-0.201] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs57440971-T	NA	NA	ROCK1P1
18	3415763	rs11081045	T	G	rs11081045	24024966	5.21E-06	Age 20-60 years	0.17	[0.1-0.24] unit decrease	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs11081045-T	NA	T	TGIF1
18	3415831	rs12457997	C	T	rs12457997	24024966	5.00E-06	Age 20-60 years	0.17	[0.096-0.237] unit increase	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs12457997-T	NA	C	TGIF1
18	23405188	rs9966832	A	G	rs9966832	24024966	5.00E-06	Age 20-81 years	0.15	[0.086-0.215] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs9966832-A	NA	A	NA
18	23764235	rs11877878	A	G	rs11877878	24024966	5.00E-06	Age 20-81 years	0.09	[0.052-0.129] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs11877878-A	NA	G	PSMA8
18	23764235	rs11877878	A	G	rs11877878	24024966	6.24E-06	Age 20-60 years	0.1	[0.06-0.14] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs11877878-A	NA	G	PSMA8
18	23764235	rs11877878	A	G	rs11877878	24024966	9.44E-06	Age 20-60 years	0.09	[0.05-0.14] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs11877878-A	NA	G	PSMA8
18	23766056	rs11873475	A	C	rs11873475	24024966	7.67E-06	Age 20-60 years	0.1	[0.05-0.14] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs11873475-A	NA	C,A	PSMA8
18	23767448	rs28688822	A	G	rs28688822	24024966	6.95E-06	Age 20-60 years	0.1	[0.06-0.14] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs28688822-A	NA	A	PSMA8
18	23767545	rs59077772	T	A	rs59077772	24024966	6.96E-06	Age 20-60 years	0.1	[0.06-0.14] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs59077772-A	NA	T	PSMA8
18	23768769	rs2121561	A	G	rs2121561	24024966	6.33E-06	Age 20-60 years	0.1	[0.06-0.14] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs2121561-A	NA	G	PSMA8
18	23776274	rs4800725	T	A	rs4800725	24024966	5.59E-06	Age 20-60 years	0.1	[0.06-0.14] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs4800725-A	NA	T	NA
18	23777560	rs9956182	G	A	rs9956182	24024966	7.32E-06	Age 20-60 years	0.1	[0.06-0.15] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs9956182-A	NA	A	NA
18	23778553	rs13381091	A	G	rs13381091	24024966	5.35E-06	Age 20-60 years	0.1	[0.06-0.14] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs13381091-A	NA	A	NA
18	23778571	rs13381092	A	T	rs13381092	24024966	5.35E-06	Age 20-60 years	0.1	[0.06-0.14] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs13381092-A	NA	A	NA
18	23778939	rs8091826	G	A	rs8091826	24024966	5.33E-06	Age 20-60 years	0.1	[0.06-0.14] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs8091826-A	NA	G	NA
18	23781301	rs59129887	G	A	rs59129887	24024966	5.23E-06	Age 20-60 years	0.1	[0.06-0.14] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs59129887-A	NA	G	NA
18	23782140	rs4800728	G	A	rs4800728	24024966	5.32E-06	Age 20-60 years	0.1	[0.06-0.15] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs4800728-A	NA	G	NA
18	23785648	rs8097810	A	G	rs8097810	24024966	4.00E-06	Age 20-60 years	0.11	[0.060-0.150] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs8097810-A	NA	A	NA
18	23785648	rs8097810	A	G	rs8097810	24024966	6.47E-06	Age 20-81 years	0.09	[0.05-0.14] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs8097810-A	NA	A	NA
18	25786880	rs11659841	C	T	rs11659841	24347629	9.00E-06	(PD1)	2.48	NA	93 European ancestry cases; 83 European ancestry individuals; 497 European ancestry controls	European(673)	ALL(673)	EUR(673)	ALL(673)	Periodontal disease-related phenotypes	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	Research Support, N.I.H., Extramural	T	NA
18	34252749	rs8094794	C	T	rs8094794	24347629	6.00E-06	(PD1)	2.17	NA	93 European ancestry cases; 83 European ancestry individuals; 497 European ancestry controls	European(673)	ALL(673)	EUR(673)	ALL(673)	Periodontal disease-related phenotypes	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	Research Support, N.I.H., Extramural	C	FHOD3
18	39940966	rs346452	G	A	rs346452	24024966	2.00E-06	Age 20-81 years	1.32	[1.18-1.47]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	A	LOC284260
18	39942308	rs346449	C	T	rs346449	24024966	6.22E-06	Age 20-81 years	1.3	[1.16-1.45]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	A	LOC284260
18	39943164	rs346445	G	A	rs346445	24024966	3.84E-06	Age 20-81 years	1.32	[1.16-1.47]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	T	LOC284260
18	40023306	rs346221	G	A	rs346221	24024966	4.00E-06	Age 20-81 years	1.31	[1.17-1.47]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs346221-A	NA	C,T	LOC284260
18	40037779	rs346195	G	A	rs346195	24024966	6.34E-06	Age 20-81 years	1.3	[1.16-1.46]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs346195-A	NA	C	LOC284260
18	40052746	rs346230	C	T	rs346230	24024966	9.23E-06	Age 20-81 years	1.3	[1.16-1.45]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs346230-T	NA	C	LOC284260
18	51473853	rs17533756	C	T	rs17533756	24024966	7.01E-06	Age 20-60 years	0.09	[0.05-0.13] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs17533756-T	NA	C	NA
18	51490042	rs7236513	G	T	rs7236513	24024966	6.09E-06	Age 20-60 years	0.09	[0.05-0.13] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs7236513-T	NA	G	NA
18	51510571	rs67283606	T	C	rs67283606	24024966	8.70E-06	Age 20-60 years	0.09	[0.05-0.13] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs67283606-T	NA	T	NA
18	51517355	rs4129335	G	C	rs4129335	24024966	7.37E-06	Age 20-60 years	0.09	[0.05-0.13] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs4129335-C	NA	C	NA
18	51519051	rs67463530	G	C	rs67463530	24024966	7.71E-06	Age 20-60 years	0.09	[0.05-0.13] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs67463530-C	NA	G	NA
18	51526568	rs1995138	G	A	rs1995138	24024966	4.00E-06	Age 20-60 years	0.1	[0.055-0.136] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs1995138-A	NA	G	NA
18	51532725	rs1826972	T	C	rs1826972	24024966	6.76E-06	Age 20-60 years	0.09	[0.05-0.13] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs1826972-T	NA	T	NA
19	5022604	rs263063	T	C	rs263063	24024966	6.00E-06	Age 20-81 years	1.63	[1.32-2.01]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs263063-T	NA	C	KDM4B
19	5080647	rs11673509	C	T	rs11673509	24024966	6.00E-06	Age 20-60 years	1.66	[1.34-2.07]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs11673509-T	NA	C	KDM4B
19	6887736	rs3826782	G	A	rs3826782	23459936	8.00E-07	Moderate CPd	2.01	[1.52-2.65]	4,504 European ancestry individuals	European(4504)	ALL(4504)	EUR(4504)	ALL(4504)	Periodontitis	HPOID:0000704	Periodontitis	DOID:824	periodontitis	D010518	Periodontitis	EFOID:0000649	periodontitis	Periodontitis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
19	18487667	rs78015699	C	T	rs78015699	24024966	7.00E-06	Age 20-60 years	0.22	[0.12-0.31] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs78015699-T	NA	C	NA
19	47796800	rs7254232	A	G	rs7254232	25008200	3.00E-06	NA	NA	NA	63 European ancestry cases; 543 European ancestry controls; up to 32 African American cases; up to 158 African American controls; up to 4 cases; up to 66 controls	NOPOP(70)	African American(190)	European(606)	ALL(866)	NOPOP(70)	AFR(190)	EUR(606)	ALL(866)	Periodontitis (Chronic)	NA	NA	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis
19	56091332	rs149546760	G	C	rs149546760	24024966	5.00E-06	Age 20-60 years	0.34	[0.19-0.48] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs149546760-C	NA	G	ZNF579
19	56111075	rs140900046	G	A	rs140900046	24024966	4.00E-06	Age 20-60 years	0.34	[0.20-0.49] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs140900046-A	NA	G	NA
20	36977636	rs11536940	G	A	rs11536940	24024966	2.00E-06	Age 20-60 years	0.38	[0.23-0.54] unit increase	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs11536940-A	NA	G	LBP
20	40840779	rs7345986	A	G	rs7345986	24024966	9.00E-06	Age 20-60 years	0.06	[0.036-0.092] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs7345986-A	NA	G	PTPRT
21	15821478	rs34893275	T	TC,TTC	rs34893275	24024966	9.65E-06	Age 20-60 years	1.47	[1.25-1.75]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	NA	NA
21	31240416	rs2268215	A	C	rs2268215	24024966	8.88E-06	Age 20-60 years	0.24	[0.13-0.34] unit increase	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs2268215-C	NA	A	GRIK1
21	31244478	rs457352	C	T	rs457352	24024966	7.00E-06	Age 20-60 years	0.24	[0.14-0.34] unit increase	up to 2,501 European ancestry individuals	European(2501)	ALL(2501)	EUR(2501)	ALL(2501)	Periodontitis (DPAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs457352-T	NA	C	GRIK1
21	32055022	rs2048126	A	G	rs2048126	25008200	8.43E-05	NA	NA	NA	63 European ancestry cases; 543 European ancestry controls; up to 32 African American cases; up to 158 African American controls; up to 4 cases; up to 66 controls	NOPOP(70)	African American(190)	European(606)	ALL(866)	NOPOP(70)	AFR(190)	EUR(606)	ALL(866)	Periodontitis (Chronic)	NA	NA	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis
21	32075211	rs9305434	C	T	rs9305434	25008200	7.91E-05	NA	NA	NA	63 European ancestry cases; 543 European ancestry controls; up to 32 African American cases; up to 158 African American controls; up to 4 cases; up to 66 controls	NOPOP(70)	African American(190)	European(606)	ALL(866)	NOPOP(70)	AFR(190)	EUR(606)	ALL(866)	Periodontitis (Chronic)	NA	NA	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis
21	32086323	rs2833017	G	T	rs2833017	25008200	5.20E-05	NA	NA	NA	63 European ancestry cases; 543 European ancestry controls; up to 32 African American cases; up to 158 African American controls; up to 4 cases; up to 66 controls	NOPOP(70)	African American(190)	European(606)	ALL(866)	NOPOP(70)	AFR(190)	EUR(606)	ALL(866)	Periodontitis (Chronic)	NA	NA	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis
21	40283733	rs9979250	C	T	rs9979250	24024966	4.00E-07	Age 20-60 years	0.15	[0.092-0.208] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs9979250-T	NA	C	FLJ45139
21	42774541	rs466092	A	G	rs466092	25008200	1.28E-05	NA	NA	NA	63 European ancestry cases; 543 European ancestry controls; up to 32 African American cases; up to 158 African American controls; up to 4 cases; up to 66 controls	NOPOP(70)	African American(190)	European(606)	ALL(866)	NOPOP(70)	AFR(190)	EUR(606)	ALL(866)	Periodontitis (Chronic)	NA	NA	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis
22	22506569	rs11089937	A	C	rs11089937	24024966	8.00E-06	Age 20-60 years	1.33	[1.17-1.51]	up to 2,969 European ancestry individuals	European(2969)	ALL(2969)	EUR(2969)	ALL(2969)	Periodontitis (PAL4Q3)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs11089937-A	NA	A	NA
22	22552114	rs9623054	C	T	rs9623054	24024966	9.97E-06	Age 20-60 years	1.31	[1.16-1.47]	up to 3,915 European ancestry individuals	European(3915)	ALL(3915)	EUR(3915)	ALL(3915)	Periodontitis (CDC/AAP)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs9623054-T	NA	C	NA
X	33811841	rs113065570	C	T	rs113065570	24024966	8.00E-06	Age 20-60 years	0.05	[0.026-0.067] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs113065570-T	NA	C	NA
X	62625199	rs10127000	G	T	rs10127000	24024966	6.00E-06	Age 20-60 years	0.1	[0.057-0.144] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs10127000-T	NA	G	NA
X	67915900	rs5980668	G	A	rs5980668	24024966	9.63E-06	Age 20-60 years	0.14	[0.08-0.21] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs5980668-A	NA	A	STARD8
X	129104734	rs2361405	A	G	rs2361405	24024966	5.00E-06	Age 20-60 years	0.07	[0.038-0.097] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs2361405-A	NA	G	NA
X	129105155	rs138595762	C	CGT,CTG	rs138595762	24024966	4.61E-06	Age 20-60 years	0.07	[0.04-0.1] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	NA	NA
X	129105155	rs58776649	C	CTG	rs138595762	24024966	4.61E-06	Age 20-60 years	0.07	[0.04-0.1] unit decrease	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	NA	NA	NA	NA
X	132024504	rs7892161	C	T	rs7892161	24024966	9.00E-06	Age 20-60 years	0.04	[0.023-0.060] unit increase	up to 4,032 European ancestry individuals	European(4032)	ALL(4032)	EUR(4032)	ALL(4032)	Periodontitis (Mean PAL)	HPOID:0000704	Periodontitis	DOID:824	periodontitis	NA	NA	NA	NA	Periodontitis	rs7892161-T	NA	T	HS6ST2

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:3)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0031099	doxycycline	D004318	564-25-0	periodontitis	MESH:D010518	therapeutic	11089368
C0031099	indomethacin	D007213	53-86-1	periodontitis	MESH:D010518	therapeutic	17225004
C0031099	rosiglitazone	C089730	-	periodontitis	MESH:D010518	therapeutic	19508902

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)