PedAM

Pediatric Disease Annotations & Medicines


	pemphigus

Disease ID	230
Disease	pemphigus
Definition	Group of chronic blistering diseases characterized histologically by ACANTHOLYSIS and blister formation within the EPIDERMIS.
Synonym	pemphigus (disorder) pemphigus [disease/finding] pemphigus nos pemphigus nos (disorder) pemphigus, nos
DOID	DOID:9182
UMLS	C0030807
MeSH	D010392
SNOMED-CT	SNOMEDCT_US_2016_09_01:65172003
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:75) C1261473 \| sarcoma \| 4 C0033860 \| psoriasis \| 4 C0024299 \| lymphoma \| 4 C0014868 \| esophagitis \| 4 C0036220 \| kaposi's sarcoma \| 3 C0029456 \| osteoporosis \| 3 C0021053 \| immune disease \| 3 C0040100 \| thymoma \| 3 C0023418 \| leukemia \| 2 C0019829 \| hodgkin lymphoma \| 2 C0003864 \| arthritis \| 2 C0030809 \| pemphigus vulgaris \| 2 C0079744 \| diffuse large b-cell lymphoma \| 2 C0019829 \| hodgkin's lymphoma \| 2 C0007137 \| squamous cell carcinoma \| 2 C0024301 \| follicular lymphoma \| 2 C0006271 \| bronchiolitis \| 2 C0024305 \| non-hodgkin's lymphoma \| 2 C0006272 \| bronchiolitis obliterans \| 2 C1260325 \| follicular dendritic cell sarcoma \| 2 C0040128 \| thyroid disease \| 2 C0037274 \| dermatosis \| 2 C0004623 \| bacterial infections \| 1 C0023434 \| chronic lymphocytic leukaemia \| 1 C0024314 \| lymphoproliferative disease \| 1 C0079731 \| b-cell lymphoma \| 1 C0019158 \| hepatitis \| 1 C0684249 \| lung carcinoma \| 1 C0085652 \| pyoderma gangrenosum \| 1 C0027873 \| neuromyelitis optica \| 1 C0023473 \| chronic myeloid leukemia \| 1 C0042721 \| viral hepatitis \| 1 C0040128 \| thyroid diseases \| 1 C0042164 \| uveitis \| 1 C0279626 \| esophageal squamous cell carcinoma \| 1 C0034212 \| pyoderma \| 1 C0019163 \| hepatitis b \| 1 C0600336 \| subcorneal pustular dermatosis \| 1 C0005586 \| bipolar disorder \| 1 C0238198 \| gastrointestinal stromal tumour \| 1 C0010414 \| cryptococcus neoformans \| 1 C0409974 \| lupus erythematosus \| 1 C0238198 \| gastrointestinal stromal tumor \| 1 C1527407 \| eosinophilic pneumonia \| 1 C0015230 \| cutaneous eruption \| 1 C0013295 \| duodenal ulcer \| 1 C0007112 \| adenocarcinoma of prostate \| 1 C0023434 \| chronic lymphocytic leukemia \| 1 C0039128 \| syphilis \| 1 C0004623 \| bacterial infection \| 1 C0042769 \| virus infection \| 1 C0017574 \| gingivitis \| 1 C0879615 \| stromal tumor \| 1 C0334254 \| lymphoepithelioma \| 1 C0032285 \| pneumonia \| 1 C0009171 \| cocaine abuse \| 1 C0019163 \| hepatitis b infection \| 1 C0024305 \| non-hodgkin lymphoma \| 1 C0035309 \| retinopathy \| 1 C0600139 \| carcinoma of prostate \| 1 C0023448 \| lymphocytic leukaemia \| 1 C0879615 \| stromal tumour \| 1 C0948265 \| metabolic syndrome \| 1 C0026764 \| multiple myeloma \| 1 C0003873 \| rheumatoid arthritis \| 1 C0019348 \| herpes simplex infection \| 1 C0334121 \| inflammatory myofibroblastic tumour \| 1 C0040137 \| thyroid nodule \| 1 C0009324 \| ulcerative colitis \| 1 C0023448 \| lymphocytic leukemia \| 1 C0019348 \| herpes simplex \| 1 C0037274 \| skin disease \| 1 C0001418 \| adenocarcinoma \| 1 C1136085 \| monoclonal gammopathy \| 1 C0023470 \| myeloid leukemia \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:2) C3 \| 718 \| CTD_human ATP2C1 \| 27032 \| GHR
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:27) 581 \| BAX \| infer 727 \| C5 \| infer 930 \| CD19 \| infer 940 \| CD28 \| infer 958 \| CD40 \| infer 959 \| CD40LG \| infer 942 \| CD86 \| infer 1493 \| CTLA4 \| infer 3105 \| HLA-A \| infer 3106 \| HLA-B \| infer 3107 \| HLA-C \| infer 3117 \| HLA-DQA1 \| infer 3119 \| HLA-DQB1 \| infer 3123 \| HLA-DRB1 \| infer 3586 \| IL10 \| infer 3552 \| IL1A \| infer 3553 \| IL1B \| infer 3557 \| IL1RN \| infer 3566 \| IL4R \| infer 3569 \| IL6 \| infer 4049 \| LTA \| infer 6891 \| TAP2 \| infer 7040 \| TGFB1 \| infer 7124 \| TNF \| infer 10673 \| TNFSF13B \| infer 7157 \| TP53 \| infer 7185 \| TRAF1 \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:127) 104940698 \| DALIR \| DISEASES 6362 \| CCL18 \| DISEASES 1015 \| CDH17 \| DISEASES 51052 \| PRLH \| DISEASES 3861 \| KRT14 \| DISEASES 7414 \| VCL \| DISEASES 6361 \| CCL17 \| DISEASES 5327 \| PLAT \| DISEASES 8797 \| TNFRSF10A \| DISEASES 2217 \| FCGRT \| DISEASES 973 \| CD79A \| DISEASES 4818 \| NKG7 \| DISEASES 3558 \| IL2 \| DISEASES 3458 \| IFNG \| DISEASES 3111 \| HLA-DOA \| DISEASES 1007 \| CDH9 \| DISEASES 3565 \| IL4 \| DISEASES 3567 \| IL5 \| DISEASES 3336 \| HSPE1 \| DISEASES 1843 \| DUSP1 \| DISEASES 667 \| DST \| DISEASES 81578 \| COL21A1 \| DISEASES 718 \| C3 \| DISEASES 6939 \| TCF15 \| DISEASES 1830 \| DSG3 \| DISEASES 1828 \| DSG1 \| DISEASES 1823 \| DSC1 \| DISEASES 3915 \| LAMC1 \| DISEASES 1144 \| CHRND \| DISEASES 3569 \| IL6 \| DISEASES 3557 \| IL1RN \| DISEASES 26525 \| IL36RN \| DISEASES 1829 \| DSG2 \| DISEASES 999 \| CDH1 \| DISEASES 9914 \| ATP2C2 \| DISEASES 57148 \| RALGAPB \| DISEASES 3552 \| IL1A \| DISEASES 55717 \| WDR11 \| DISEASES 28960 \| DCPS \| DISEASES 5317 \| PKP1 \| DISEASES 5443 \| POMC \| DISEASES 28990 \| ASTE1 \| DISEASES 122481 \| AK7 \| DISEASES 255626 \| HIST1H2BA \| DISEASES 1824 \| DSC2 \| DISEASES 1636 \| ACE \| DISEASES 1145 \| CHRNE \| DISEASES 27306 \| HPGDS \| DISEASES 55764 \| IFT122 \| DISEASES 27242 \| TNFRSF21 \| DISEASES 5055 \| SERPINB2 \| DISEASES 144568 \| A2ML1 \| DISEASES 3904 \| LAIR2 \| DISEASES 2125 \| EVPL \| DISEASES 6037 \| RNASE3 \| DISEASES 1493 \| CTLA4 \| DISEASES 81851 \| KRTAP1-1 \| DISEASES 80777 \| CYB5B \| DISEASES 5897 \| RAG2 \| DISEASES 5340 \| PLG \| DISEASES 836 \| CASP3 \| DISEASES 3728 \| JUP \| DISEASES 8832 \| CD84 \| DISEASES 55584 \| CHRNA9 \| DISEASES 120103 \| SLC36A4 \| DISEASES 29851 \| ICOS \| DISEASES 5339 \| PLEC \| DISEASES 491 \| ATP2B2 \| DISEASES 940 \| CD28 \| DISEASES 3812 \| KIR3DL2 \| DISEASES 10250 \| SRRM1 \| DISEASES 29110 \| TBK1 \| DISEASES 11187 \| PKP3 \| DISEASES 6401 \| SELE \| DISEASES 201475 \| RAB12 \| DISEASES 5329 \| PLAUR \| DISEASES 3117 \| HLA-DQA1 \| DISEASES 5493 \| PPL \| DISEASES 1308 \| COL17A1 \| DISEASES 344905 \| ATP13A5 \| DISEASES 921 \| CD5 \| DISEASES 79723 \| SUV39H2 \| DISEASES 100506658 \| OCLN \| DISEASES 10219 \| KLRG1 \| DISEASES 487 \| ATP2A1 \| DISEASES 6714 \| SRC \| DISEASES 728113 \| ANXA8L1 \| DISEASES 147409 \| DSG4 \| DISEASES 489 \| ATP2A3 \| DISEASES 3123 \| HLA-DRB1 \| DISEASES 3135 \| HLA-G \| DISEASES 1825 \| DSC3 \| DISEASES 1380 \| CR2 \| DISEASES 356 \| FASLG \| DISEASES 3713 \| IVL \| DISEASES 4942 \| OAT \| DISEASES 8416 \| ANXA9 \| DISEASES 959 \| CD40LG \| DISEASES 2219 \| FCN1 \| DISEASES 958 \| CD40 \| DISEASES 5328 \| PLAU \| DISEASES 2155 \| F7 \| DISEASES 10673 \| TNFSF13B \| DISEASES 50943 \| FOXP3 \| DISEASES 7133 \| TNFRSF1B \| DISEASES 3105 \| HLA-A \| DISEASES 8718 \| TNFRSF25 \| DISEASES 1832 \| DSP \| DISEASES 3903 \| LAIR1 \| DISEASES 27032 \| ATP2C1 \| DISEASES 3119 \| HLA-DQB1 \| DISEASES 3120 \| HLA-DQB2 \| DISEASES 4719 \| NDUFS1 \| DISEASES 64065 \| PERP \| DISEASES 374868 \| ATP9B \| DISEASES 960 \| CD44 \| DISEASES 7124 \| TNF \| DISEASES 387 \| RHOA \| DISEASES 3612 \| IMPA1 \| DISEASES 3586 \| IL10 \| DISEASES 54872 \| PIGG \| DISEASES 51428 \| DDX41 \| DISEASES 83481 \| EPPK1 \| DISEASES 930 \| CD19 \| DISEASES 488 \| ATP2A2 \| DISEASES 1006 \| CDH8 \| DISEASES 677833 \| SNORA54 \| DISEASES
Locus	(Waiting for update.)

Disease ID	230
Disease	pemphigus
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:51) HP:0100792 \| Acantholysis \| 10 HP:0008066 \| Skin bullae \| 6 HP:0002960 \| Autoimmune condition \| 6 HP:0030731 \| Carcinoma \| 4 HP:0100633 \| Inflammation of the esophagus \| 4 HP:0003765 \| Psoriasis \| 4 HP:0100242 \| Sarcoma \| 4 HP:0012189 \| Hodgkin disease \| 4 HP:0002665 \| Lymphoma \| 3 HP:0100726 \| Kaposi's sarcoma \| 3 HP:0100522 \| Thymoma \| 3 HP:0000939 \| Osteoporosis \| 3 HP:0011946 \| Constrictive bronchiolitis \| 2 HP:0000820 \| Thyroid abnormality \| 2 HP:0011950 \| Bronchiolitis \| 2 HP:0002860 \| Squamous cell carcinoma \| 2 HP:0002664 \| Neoplasia \| 2 HP:0001369 \| Arthritis \| 2 HP:0000230 \| Inflamed gums \| 1 HP:0100583 \| Corneal perforation \| 1 HP:0200041 \| Skin erosion \| 1 HP:0001945 \| Fever \| 1 HP:0200039 \| Pustules \| 1 HP:0100825 \| Inflammation of the lips \| 1 HP:0002239 \| Gastrointestinal hemorrhage \| 1 HP:0000999 \| Pyoderma \| 1 HP:0000554 \| Uveitis \| 1 HP:0012324 \| Myeloid leukemia \| 1 HP:0002090 \| Pneumonia \| 1 HP:0012531 \| Pain \| 1 HP:0001298 \| Encephalopathy \| 1 HP:0002955 \| Granulomatosis \| 1 HP:0200037 \| Skin vesicle \| 1 HP:0000488 \| Noninflammatory retina disease \| 1 HP:0010783 \| Erythema \| 1 HP:0006775 \| Multiple myeloma \| 1 HP:0002584 \| Intestinal hemorrhage \| 1 HP:0012539 \| Non-Hodgkin lymphoma \| 1 HP:0008069 \| Neoplasm of the skin \| 1 HP:0001909 \| Leukemia \| 1 HP:0100723 \| Gastrointestinal stroma tumor \| 1 HP:0100806 \| Sepsis \| 1 HP:0001370 \| Rheumatoid arthritis \| 1 HP:0012115 \| Liver inflammation \| 1 HP:0002588 \| Duodenal ulcer \| 1 HP:0001019 \| Exfoliative dermititis \| 1 HP:0005506 \| Chronic myeloid leukemia \| 1 HP:0030318 \| Commissural cheilitis \| 1 HP:0012191 \| B-cell lymphoma \| 1 HP:0006562 \| Viral hepatitis \| 1 HP:0007302 \| Bipolar disorder \| 1

Disease ID	230
Disease	pemphigus
Manually Symptom	UMLS \| Name(Total Manually Symptoms:15) C2364133 \| infection C1373218 \| immunosuppression C0849640 \| skin damage C0406653 \| eosinophilic spongiosis C0279705 \| epithelial thymoma C0038826 \| superinfection C0038362 \| stomatitis C0037284 \| skin lesions C0029166 \| oral manifestations C0026636 \| oral disease C0025517 \| metabolism disorders C0019360 \| herpes zoster infection C0019348 \| herpes simplex infections C0014038 \| encephalitis C0007861 \| cervicitis
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:3) C0406653 \| eosinophilic spongiosis \| 1 C0029166 \| oral manifestations \| 1 C0009450 \| infection \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:62)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
1	213811721	rs7529857	T	G	rs7529857	22437316	7.64E-04	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	T	NA
3	35475083	rs1378394	T	C	rs1378394	22437316	8.03E-04	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	G	NA
3	103811702	rs1345189	A	G	rs1345189	22437316	1.10E-04	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	A	NA
6	31052684	rs2535311	A	G	rs2535311	22437316	8.05E-04	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	T	NA
6	31084435	rs1062470	G	A	rs1062470	22437316	4.10E-04	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	C	CDSN
6	31091862	rs3094205	A	G	rs3094205	22437316	4.11E-04	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	T	PSORS1C1
6	31091862	rs560839399	A	G	rs3094205	22437316	4.11E-04	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	T	PSORS1C1
6	31092124	rs3778638	G	A	rs3778638	22437316	4.51E-04	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	G	PSORS1C1
6	31092124	rs527680481	G	A	rs3778638	22437316	4.51E-04	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	G	PSORS1C1
6	31438368	rs2244839	G	A	rs2244839	22437316	1.22E-07	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	NA	HCG26
6	31440082	rs1055569	C	T	rs1055569	22437316	5.28E-05	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	NA	NA
6	31440497	rs2516440	G	A	rs2516440	22437316	6.92E-05	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	NA	HCG26
6	31443323	rs12660382	C	T	rs12660382	22437316	5.60E-11	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	NA	NA
6	31445909	rs2395488	A	G	rs2395488	22437316	3.98E-12	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	NA	NA
6	31446466	rs2248372	G	A	rs2248372	22437316	1.90E-06	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	NA	NA
6	31448315	rs2516424	A	G	rs2516424	22437316	1.43E-12	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	NA	NA
6	31449778	rs2523647	A	G	rs2523647	22437316	8.98E-15	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	NA	NA
6	31476854	rs2844498	C	T	rs2844498	22437316	1.44E-05	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	G	MICB
6	31478986	rs2246618	C	T	rs2246618	22437316	4.58E-11	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	C	MICB
6	31726688	rs707939	C	A	rs707939	22437316	2.07E-05	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	G	MSH5
6	31777946	rs2075800	C	T	rs2075800	22437316	2.88E-05	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	G	HSPA1L
6	31838713	rs494620	G	A	rs494620	22437316	4.10E-04	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	G	SLC44A4
6	31843924	rs2736428	C	T	rs2736428	22437316	1.96E-04	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	G	SLC44A4
6	31946614	rs6941112	G	A	rs6941112	22437316	1.90E-07	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	G	STK19
6	32030284	rs2239689	G	A	rs2239689	22437316	1.44E-05	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	C	TNXB
6	32038700	rs2071295	C	T	rs2071295	22437316	1.03E-05	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	G	TNXB
6	32083175	rs8111	C	T	rs8111	22437316	1.44E-05	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	G	ATF6B
6	32179896	rs2071286	C	T	rs2071286	22437316	5.21E-08	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	G	NOTCH4
6	32190406	rs443198	A	G	rs443198	22437316	1.08E-08	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	T	NOTCH4
6	32190620	rs3134931	T	C	rs3134931	22437316	6.82E-05	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	A	NOTCH4
6	32191041	rs434841	G	A	rs434841	22437316	6.88E-05	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	A	NOTCH4
6	32195017	rs482759	A	G	rs482759	22437316	7.92E-10	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	T	NA
6	32218843	rs3115573	A	G	rs3115573	22437316	8.06E-06	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	T	NA
6	32220685	rs3130315	G	A	rs3130315	22437316	8.06E-06	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	G	NA
6	32346794	rs1980495	A	C	rs1980495	22437316	3.02E-09	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	G	NA
6	32348145	rs2395157	A	G	rs2395157	22437316	1.52E-08	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	A	NA
6	32354428	rs4424066	A	G	rs4424066	22437316	8.68E-06	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	G	NA
6	32361111	rs3817973	C	T	rs3817973	22437316	8.68E-06	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	A	HCG23
6	32363816	rs2076530	T	C	rs2076530	22437316	5.28E-05	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	G	BTNL2
6	32368087	rs3817963	T	C	rs3817963	22437316	1.91E-06	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	A	BTNL2
6	32373698	rs3806156	G	T	rs3806156	22437316	4.29E-06	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	G	BTNL2
6	32375973	rs3763309	C	A	rs3763309	22437316	1.03E-16	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	C	BTNL2
6	32384721	rs9268542	A	G	rs9268542	22437316	4.91E-09	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	A	NA
6	32387809	rs2395163	T	C	rs2395163	22437316	3.01E-14	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	T	NA
6	32570400	rs2516049	T	C	rs2516049	22437316	1.85E-07	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	A	LOC100507709
6	32577380	rs660895	A	G	rs660895	22437316	2.70E-19	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	A	NA
6	32654714	rs9275184	T	C	rs9275184	22437316	7.69E-21	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	T	NA
6	32655218	rs2856683	T	G	rs2856683	22437316	2.30E-06	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	A	NA
6	32663564	rs5000634	A	G	rs5000634	22437316	1.87E-06	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	T	NA
6	32665728	rs9275312	A	G	rs9275312	22437316	2.12E-19	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	A	NA
6	32669156	rs9275390	T	C	rs9275390	22437316	2.63E-08	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	C	NA
6	32669767	rs2647050	T	C	rs2647050	22437316	4.29E-06	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	T	NA
6	32670255	rs2856718	C	T	rs2856718	22437316	4.29E-06	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	G	NA
6	32680970	rs7745656	G	T	rs7745656	22437316	5.28E-05	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	G	NA
6	32681277	rs2858331	A	G	rs2858331	22437316	3.95E-10	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	T	NA
6	32682862	rs3892710	C	T	rs3892710	22437316	3.39E-09	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	T	NA
6	32685550	rs3916765	G	A	rs3916765	22437316	3.39E-17	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	G	NA
6	32797876	rs241436	A	G	rs241436	22437316	6.70E-04	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	C	TAP2
8	53137329	rs4074067	C	T	rs4074067	22437316	4.10E-04	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	T	ST18
8	53193238	rs4639533	C	T	rs4639533	22437316	2.21E-04	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	C,T	ST18
9	27894682	rs1316922	G	A	rs1316922	22437316	4.08E-04	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	C	NA
22	37347959	rs8137446	C	T	rs8137446	22437316	2.03E-04	NA	NA	NA	100 Jewish ancestry cases; 397 Jewish ancestry controls	Jewish(497)	ALL(497)	MEA(497)	ALL(497)	Pemphigus vulgaris	HPOID:0002960	Autoimmunity	DOID:9182	pemphigus	D010392	Pemphigus	NA	NA	Skin disease	NA	Research Support, Non-U.S. Gov't	C	NA

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:1)
HP ID	HP Name	MP ID	MP Name	Annotation
HP:0002383	Encephalitis	MP:0005332	abnormal amino acid level;HP:0010280	Stomatitis

Chemical(Total Drugs:2)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0030807	cyclophosphamide	D003520	50-18-0	pemphigus	MESH:D010392	therapeutic	16207182
C0030807	cyclosporine	D016572	59865-13-3	pemphigus	MESH:D010392	therapeutic	8176015

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)