PedAM
Pediatric Disease Annotations & Medicines
| paraneoplastic cerebellar degeneration | ||||
| Disease ID | 1377 |
|---|---|
| Disease | paraneoplastic cerebellar degeneration |
| Definition | Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS, PATHOLOGIC. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686) |
| Synonym | cerebellar ataxia due to neoplasia cerebellar degeneration paraneopl cerebellar degeneration, paraneoplastic cerebellar syndrome paraneopl cerebellar syndrome, paraneoplastic cerebellar syndromes, paraneoplastic degeneration, paraneoplastic cerebellar paraneopl cerebellar degeneration paraneopl cerebellar syndrome paraneoplastic cerebellar degeneration (disorder) paraneoplastic cerebellar degeneration [disease/finding] paraneoplastic cerebellar syndrome paraneoplastic cerebellar syndromes |
| UMLS | C0393534 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:31) C0001418 | adenocarcinoma | 3 C1140680 | ovarian cancer | 3 C1140680 | ovarian ca | 3 C0006142 | breast cancer | 2 C0024299 | lymphoma | 2 C0042075 | urological disorders | 1 C0005684 | bladder cancer | 1 C0007137 | squamous cell carcinoma | 1 C0206701 | serous carcinoma | 1 C0027765 | neurological disorders | 1 C0684249 | carcinoma of the lung | 1 C0024301 | follicular lymphoma | 1 C0242379 | lung cancer | 1 C0019829 | hodgkin lymphoma | 1 C0004134 | ataxia | 1 C0149925 | small cell lung cancer | 1 C0007112 | adenocarcinoma of the prostate | 1 C0007097 | epithelial carcinoma | 1 C0027765 | neurological disorder | 1 C0019829 | hodgkin's lymphoma | 1 C0677886 | carcinoma of the ovary | 1 C0005586 | bipolar disorder | 1 C0812413 | pleural malignant mesothelioma | 1 C0345967 | malignant mesothelioma | 1 C0206718 | ganglioneuroblastoma | 1 C0007129 | merkel cell carcinoma | 1 C1335177 | ovarian serous carcinoma | 1 C0334254 | lymphoepithelial carcinoma | 1 C0678222 | breast carcinoma | 1 C0149782 | squamous cell carcinoma of the lung | 1 C0600139 | carcinoma of the prostate | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | (Waiting for update.) |
| Locus | (Waiting for update.) |
| Disease ID | 1377 |
|---|---|
| Disease | paraneoplastic cerebellar degeneration |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:13) HP:0030731 | Carcinoma | 4 HP:0003002 | Breast carcinoma | 3 HP:0012189 | Hodgkin disease | 2 HP:0002665 | Lymphoma | 2 HP:0100013 | Tumours of the breast | 2 HP:0002860 | Squamous cell carcinoma | 1 HP:0009725 | Bladder neoplasm | 1 HP:0002960 | Autoimmune condition | 1 HP:0030357 | Small cell lung carcinoma | 1 HP:0001251 | Ataxia | 1 HP:0006747 | Ganglioneuroblastoma | 1 HP:0100001 | Malignant mesothelioma | 1 HP:0007302 | Bipolar disorder | 1 |
| Disease ID | 1377 |
|---|---|
| Disease | paraneoplastic cerebellar degeneration |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:2) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:1) |
Manually Genotype(Total Text Mining Genotypes:0) |
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All Snps(Total Genotypes:0) | |
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GWASdb Snp Trait(Total Genotypes:0) | |
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Mapped by lexical matching(Total Items:0) |
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Mapped by homologous gene(Total Items:0) |
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Chemical(Total Drugs:0) | |
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FDA approved drug and dosage information(Total Drugs:0) | |
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FDA labeling changes(Total Drugs:0) | |
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