PedAM

Pediatric Disease Annotations & Medicines


	panic disorder

Disease ID	383
Disease	panic disorder
Definition	A type of anxiety disorder characterized by unexpected panic attacks that last minutes or, rarely, hours. Panic attacks begin with intense apprehension, fear or terror and, often, a feeling of impending doom. Symptoms experienced during a panic attack include dyspnea or sensations of being smothered; dizziness, loss of balance or faintness; choking sensations; palpitations or accelerated heart rate; shakiness; sweating; nausea or other form of abdominal distress; depersonalization or derealization; paresthesias; hot flashes or chills; chest discomfort or pain; fear of dying and fear of not being in control of oneself or going crazy. Agoraphobia may also develop. Similar to other anxiety disorders, it may be inherited as an autosomal dominant trait.
Synonym	#NAME? [x]panic disorder [episodic paroxysmal anxiety] [x]panic disorder [episodic paroxysmal anxiety] (disorder) [x]panic disorder [episodic paroxysmal anxiety] (finding) disorder, panic disorders, panic episodic paroxysmal anxiety disorder panic anxiety syndrome panic dis panic disorder (disorder) panic disorder (finding) panic disorder [disease/finding] panic disorders
OMIM	OMIM:167870
DOID	DOID:594
UMLS	C0030319
MeSH	D016584
SNOMED-CT	SNOMEDCT_US_2016_09_01:371631005
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:42) C0001818 \| agoraphobia \| 168 C0003467 \| anxiety \| 23 C0041696 \| major depressive disorder \| 15 C0011570 \| depression \| 9 C0003469 \| anxiety disorder \| 9 C0031572 \| social phobia \| 8 C0002020 \| alexithymia \| 5 C0041696 \| major depression \| 4 C0270549 \| generalized anxiety disorder \| 4 C0005586 \| bipolar disorder \| 4 C0003469 \| anxiety disorders \| 4 C0036341 \| schizophrenia \| 3 C0014544 \| epilepsy \| 3 C0149931 \| migraine \| 3 C0024115 \| pulmonary disease \| 3 C0024117 \| chronic obstructive pulmonary disease \| 3 C0600260 \| obstructive pulmonary disease \| 3 C0236801 \| specific phobia \| 2 C0013415 \| dysthymia \| 2 C0020550 \| hyperthyroidism \| 2 C0006012 \| borderline personality disorder \| 2 C0004096 \| asthma \| 2 C0031212 \| personality disorders \| 2 C0010068 \| coronary artery disease \| 2 C0024117 \| chronic obstructive pulmonary disease (copd) \| 2 C0598608 \| hyperhomocysteinemia \| 1 C0020538 \| hypertension \| 1 C0037315 \| sleep apnea syndrome \| 1 C0017178 \| gastrointestinal disorders \| 1 C0003125 \| anorexia nervosa \| 1 C0683416 \| depersonalization disorder \| 1 C0020604 \| hypochondria \| 1 C0038436 \| post-traumatic stress disorder \| 1 C0520679 \| obstructive sleep apnea syndrome \| 1 C0033975 \| psychotic disorder \| 1 C0037315 \| sleep apnea \| 1 C0018801 \| heart failure \| 1 C0028768 \| obsessive-compulsive disorder \| 1 C0012746 \| dissociative disorder \| 1 C0017178 \| gastrointestinal disorder \| 1 C0027051 \| heart attack \| 1 C0520679 \| obstructive sleep apnea \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:9) INS \| 3630 \| CTD_human ADORA2A \| 135 \| CTD_human COMT \| 1312 \| CTD_human PKP1 \| 5317 \| GWASCAT CCKBR \| 887 \| CTD_human CALCOCO1 \| 57658 \| GWASCAT ADRA2A \| 150 \| CTD_human ANO2 \| 57101 \| GWASCAT SDK2 \| 54549 \| GWASCAT
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:58) 134 \| ADORA1 \| infer 135 \| ADORA2A \| infer 57101 \| ANO2 \| infer 551 \| AVP \| infer 552 \| AVPR1A \| infer 553 \| AVPR1B \| infer 627 \| BDNF \| infer 57658 \| CALCOCO1 \| infer 885 \| CCK \| infer 886 \| CCKAR \| infer 887 \| CCKBR \| infer 1137 \| CHRNA4 \| infer 1191 \| CLU \| infer 1312 \| COMT \| infer 1390 \| CREM \| infer 1392 \| CRH \| infer 1394 \| CRHR1 \| infer 1395 \| CRHR2 \| infer 343727 \| CYCSP42 \| infer 1812 \| DRD1 \| infer 345757 \| FAM174A \| infer 2560 \| GABRB1 \| infer 51083 \| GAL \| infer 2739 \| GLO1 \| infer 2917 \| GRM7 \| infer 2922 \| GRP \| infer 2925 \| GRPR \| infer 2989 \| GULOP \| infer 3350 \| HTR1A \| infer 3351 \| HTR1B \| infer 3356 \| HTR2A \| infer 3358 \| HTR2C \| infer 389434 \| IYD \| infer 3738 \| KCNA3 \| infer 3939 \| LDHA \| infer 3945 \| LDHB \| infer 4128 \| MAOA \| infer 4916 \| NTRK3 \| infer 5241 \| PGR \| infer 5317 \| PKP1 \| infer 57480 \| PLEKHG1 \| infer 5901 \| RAN \| infer 5997 \| RGS2 \| infer 6000 \| RGS7 \| infer 100270753 \| RPL21P112 \| infer 729646 \| RPL31P4 \| infer 100131905 \| RPS27P21 \| infer 388556 \| RPS9P4 \| infer 54549 \| SDK2 \| infer 6530 \| SLC6A2 \| infer 6532 \| SLC6A4 \| infer 54498 \| SMOX \| infer 6869 \| TACR1 \| infer 27242 \| TNFRSF21 \| infer 7166 \| TPH1 \| infer 121278 \| TPH2 \| infer 706 \| TSPO \| infer 29761 \| USP25 \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:197) 2554 \| GABRA1 \| DISEASES 51052 \| PRLH \| DISEASES 1815 \| DRD4 \| DISEASES 4710 \| NDUFB4 \| DISEASES 26575 \| RGS17 \| DISEASES 328 \| APEX1 \| DISEASES 6530 \| SLC6A2 \| DISEASES 6618 \| SNAPC2 \| DISEASES 40 \| ASIC2 \| DISEASES 1075 \| CTSC \| DISEASES 41 \| ASIC1 \| DISEASES 55907 \| CMAS \| DISEASES 5754 \| PTK7 \| DISEASES 9450 \| LY86 \| DISEASES 2908 \| NR3C1 \| DISEASES 5997 \| RGS2 \| DISEASES 2691 \| GHRH \| DISEASES 27230 \| SERP1 \| DISEASES 140735 \| DYNLL2 \| DISEASES 4852 \| NPY \| DISEASES 23780 \| APOL2 \| DISEASES 7166 \| TPH1 \| DISEASES 51540 \| SCLY \| DISEASES 7024 \| TFCP2 \| DISEASES 80896 \| NPL \| DISEASES 3357 \| HTR2B \| DISEASES 2572 \| GAD2 \| DISEASES 5004 \| ORM1 \| DISEASES 6519 \| SLC3A1 \| DISEASES 9360 \| PPIG \| DISEASES 6532 \| SLC6A4 \| DISEASES 4969 \| OGN \| DISEASES 2901 \| GRIK5 \| DISEASES 57084 \| SLC17A6 \| DISEASES 2033 \| EP300 \| DISEASES 5317 \| PKP1 \| DISEASES 54431 \| DNAJC10 \| DISEASES 8452 \| CUL3 \| DISEASES 2743 \| GLRB \| DISEASES 5443 \| POMC \| DISEASES 11343 \| MGLL \| DISEASES 64083 \| GOLPH3 \| DISEASES 4883 \| NPR3 \| DISEASES 1390 \| CREM \| DISEASES 7375 \| USP4 \| DISEASES 4986 \| OPRK1 \| DISEASES 51083 \| GAL \| DISEASES 55749 \| CCAR1 \| DISEASES 8477 \| GPR65 \| DISEASES 5409 \| PNMT \| DISEASES 6531 \| SLC6A3 \| DISEASES 90226 \| UCN2 \| DISEASES 6715 \| SRD5A1 \| DISEASES 2559 \| GABRA6 \| DISEASES 3358 \| HTR2C \| DISEASES 1392 \| CRH \| DISEASES 4915 \| NTRK2 \| DISEASES 2823 \| GPM6A \| DISEASES 51594 \| NBAS \| DISEASES 55079 \| FEZF2 \| DISEASES 9320 \| TRIP12 \| DISEASES 26060 \| APPL1 \| DISEASES 1636 \| ACE \| DISEASES 89858 \| SIGLEC12 \| DISEASES 3060 \| HCRT \| DISEASES 2560 \| GABRB1 \| DISEASES 886 \| CCKAR \| DISEASES 7349 \| UCN \| DISEASES 51151 \| SLC45A2 \| DISEASES 115825 \| WDFY2 \| DISEASES 552 \| AVPR1A \| DISEASES 2562 \| GABRB3 \| DISEASES 6632 \| SNRPD1 \| DISEASES 54442 \| KCTD5 \| DISEASES 4054 \| LTBP3 \| DISEASES 5368 \| PNOC \| DISEASES 5617 \| PRL \| DISEASES 116844 \| LRG1 \| DISEASES 51181 \| DCXR \| DISEASES 6869 \| TACR1 \| DISEASES 3094 \| HINT1 \| DISEASES 2525 \| FUT3 \| DISEASES 2915 \| GRM5 \| DISEASES 2353 \| FOS \| DISEASES 80131 \| LRRC8E \| DISEASES 285335 \| SLC9C1 \| DISEASES 1501 \| CTNND2 \| DISEASES 348980 \| HCN1 \| DISEASES 624 \| BDKRB2 \| DISEASES 56945 \| MRPS22 \| DISEASES 1375 \| CPT1B \| DISEASES 10713 \| USP39 \| DISEASES 54862 \| CC2D1A \| DISEASES 3352 \| HTR1D \| DISEASES 57101 \| ANO2 \| DISEASES 3350 \| HTR1A \| DISEASES 124842 \| TMEM132E \| DISEASES 6863 \| TAC1 \| DISEASES 5032 \| P2RY11 \| DISEASES 80758 \| PRR7 \| DISEASES 1812 \| DRD1 \| DISEASES 706 \| TSPO \| DISEASES 121278 \| TPH2 \| DISEASES 277 \| AMY1B \| DISEASES 5142 \| PDE4B \| DISEASES 80258 \| EFHC2 \| DISEASES 51738 \| GHRL \| DISEASES 887 \| CCKBR \| DISEASES 2558 \| GABRA5 \| DISEASES 885 \| CCK \| DISEASES 135 \| ADORA2A \| DISEASES 160851 \| DGKH \| DISEASES 57142 \| RTN4 \| DISEASES 1576 \| CYP3A4 \| DISEASES 3363 \| HTR7 \| DISEASES 9402 \| GRAP2 \| DISEASES 4889 \| NPY5R \| DISEASES 349565 \| NMNAT3 \| DISEASES 4128 \| MAOA \| DISEASES 347468 \| OR13H1 \| DISEASES 1395 \| CRHR2 \| DISEASES 4882 \| NPR2 \| DISEASES 1544 \| CYP1A2 \| DISEASES 6633 \| SNRPD2 \| DISEASES 2918 \| GRM8 \| DISEASES 80833 \| APOL3 \| DISEASES 6050 \| RNH1 \| DISEASES 3359 \| HTR3A \| DISEASES 2917 \| GRM7 \| DISEASES 2571 \| GAD1 \| DISEASES 57480 \| PLEKHG1 \| DISEASES 79694 \| MANEA \| DISEASES 8936 \| WASF1 \| DISEASES 387129 \| NPSR1 \| DISEASES 1002 \| CDH4 \| DISEASES 1565 \| CYP2D6 \| DISEASES 4916 \| NTRK3 \| DISEASES 56477 \| CCL28 \| DISEASES 1312 \| COMT \| DISEASES 4860 \| PNP \| DISEASES 4886 \| NPY1R \| DISEASES 1813 \| DRD2 \| DISEASES 6000 \| RGS7 \| DISEASES 9641 \| IKBKE \| DISEASES 553 \| AVPR1B \| DISEASES 1118 \| CHIT1 \| DISEASES 2494 \| NR5A2 \| DISEASES 10090 \| UST \| DISEASES 26227 \| PHGDH \| DISEASES 3351 \| HTR1B \| DISEASES 278 \| AMY1C \| DISEASES 276 \| AMY1A \| DISEASES 3062 \| HCRTR2 \| DISEASES 81030 \| ZBP1 \| DISEASES 1557 \| CYP2C19 \| DISEASES 11128 \| POLR3A \| DISEASES 3061 \| HCRTR1 \| DISEASES 8518 \| IKBKAP \| DISEASES 267012 \| DAOA \| DISEASES 54518 \| APBB1IP \| DISEASES 4878 \| NPPA \| DISEASES 388585 \| HES5 \| DISEASES 79823 \| CAMKMT \| DISEASES 3356 \| HTR2A \| DISEASES 2098 \| ESD \| DISEASES 2625 \| GATA3 \| DISEASES 2925 \| GRPR \| DISEASES 8544 \| PIR \| DISEASES 10522 \| DEAF1 \| DISEASES 1814 \| DRD3 \| DISEASES 54549 \| SDK2 \| DISEASES 26022 \| TMEM98 \| DISEASES 5660 \| PSAP \| DISEASES 2912 \| GRM2 \| DISEASES 594857 \| NPS \| DISEASES 10345 \| TRDN \| DISEASES 1394 \| CRHR1 \| DISEASES 2897 \| GRIK1 \| DISEASES 10747 \| MASP2 \| DISEASES 8505 \| PARG \| DISEASES 348180 \| CTU2 \| DISEASES 23210 \| JMJD6 \| DISEASES 10163 \| WASF2 \| DISEASES 4908 \| NTF3 \| DISEASES 121256 \| TMEM132D \| DISEASES 34 \| ACADM \| DISEASES 3925 \| STMN1 \| DISEASES 389549 \| FEZF1 \| DISEASES 627 \| BDNF \| DISEASES 4045 \| LSAMP \| DISEASES 388015 \| RTL1 \| DISEASES 1622 \| DBI \| DISEASES 57658 \| CALCOCO1 \| DISEASES 91056 \| AP5B1 \| DISEASES 102723508 \| KANTR \| DISEASES 191585 \| PLAC4 \| DISEASES 6023 \| RMRP \| DISEASES
Locus	(Waiting for update.)

Disease ID	383
Disease	panic disorder
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:35) HP:0000756 \| Fear of open spaces \| 168 HP:0000739 \| Anxiety \| 23 HP:0000716 \| Depression \| 9 HP:0002883 \| Rapid breathing \| 5 HP:0007302 \| Bipolar disorder \| 4 HP:0100753 \| Schizophrenia \| 3 HP:0002076 \| Migraine headaches \| 3 HP:0100710 \| Impulsivity \| 3 HP:0012075 \| Personality disorder \| 3 HP:0006510 \| Chronic obstructive pulmonary disease \| 3 HP:0000836 \| Overactive thyroid \| 2 HP:0002099 \| Asthma \| 2 HP:0100749 \| Thoracic pain \| 2 HP:0002315 \| Headaches \| 2 HP:0001677 \| Coronary artery disease \| 2 HP:0012076 \| Borderline personality disorder \| 2 HP:0001297 \| Cerebral vascular events \| 1 HP:0012649 \| Increased inflammatory response \| 1 HP:0002870 \| Obstructive sleep apnea \| 1 HP:0001635 \| Congestive heart failure \| 1 HP:0001962 \| Palpitations \| 1 HP:0002104 \| Absence of spontaneous respiration \| 1 HP:0005537 \| Small platelet size \| 1 HP:0000822 \| Hypertension \| 1 HP:0000708 \| Behavioral problems \| 1 HP:0010535 \| Sleep apnea \| 1 HP:0001658 \| Myocardial infarction \| 1 HP:0000718 \| Aggressive behaviour \| 1 HP:0001250 \| Seizures \| 1 HP:0002039 \| Anorexia \| 1 HP:0002353 \| Abnormal EEG \| 1 HP:0000722 \| Obsessive compulsive disorder \| 1 HP:0100033 \| Tic disorder \| 1 HP:0011877 \| Increased mean platelet volume \| 1 HP:0002271 \| Autonomic dysregulation \| 1

Disease ID	383
Disease	panic disorder
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:14) C0001818 \| agoraphobia \| 168 C0003467 \| anxiety \| 23 C0011570 \| depression \| 9 C0031572 \| social phobia \| 8 C0002020 \| alexithymia \| 5 C0003469 \| anxiety disorders \| 4 C0041696 \| major depression \| 4 C0031212 \| personality disorders \| 2 C0008031 \| chest pain \| 2 C0020550 \| hyperthyroidism \| 2 C0231303 \| distress \| 1 C0012833 \| dizziness \| 1 C0037090 \| respiratory symptoms \| 1 C0559031 \| functional gastrointestinal disorders \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:59)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs12061304	19165232	3738	KCNA3	umls:C0030319	GAD	[Genome-wide association study of panic disorder in the Japanese population.]	0.002367032	2009	NA	1	110695063	A	G
rs12579350	19165232	57101	ANO2	umls:C0030319	GAD	[As a result, seven SNPs were significantly associated with PD, which were located in or adjacent to genes including PKP1, PLEKHG1, TMEM16B, CALCOCO1, SDK2 and CLU (or APO-J).]	0.122638474	2009	ANO2	12	5687935	G	A
rs12579350	19165232	57101	ANO2	umls:C0030319	GWASCAT	As a result, seven SNPs were significantly associated with PD, which were located in or adjacent to genes including PKP1, PLEKHG1, TMEM16B, CALCOCO1, SDK2 and CLU (or APO-J).	0.122638474	2009	ANO2	12	5687935	G	A
rs1386494	18832011	3356	HTR2A	umls:C0030319	BeFree	Nine gene-candidates, including 5-HTTLPR, MAO-A VNTR, TPH2 rs1386494, 5-HTR1A -1019C-G, 5-HTR2A 102T-C, CCKR1 246G-A, CCKR2 -215C-A, DRD1 -94G-A and COMT Val158Met, were selected for genotyping based on previous positive findings from genetic association studies in PD.	0.019726837	2008	TPH2	12	71958763	T	C
rs1386494	18832011	1312	COMT	umls:C0030319	BeFree	Nine gene-candidates, including 5-HTTLPR, MAO-A VNTR, TPH2 rs1386494, 5-HTR1A -1019C-G, 5-HTR2A 102T-C, CCKR1 246G-A, CCKR2 -215C-A, DRD1 -94G-A and COMT Val158Met, were selected for genotyping based on previous positive findings from genetic association studies in PD.	0.162449467	2008	TPH2	12	71958763	T	C
rs16989303	19165232	54498	SMOX	umls:C0030319	GAD	[Genome-wide association study of panic disorder in the Japanese population.]	0.002367032	2009	NA	20	4188432	G	A
rs17466684	19165232	1191	CLU	umls:C0030319	GAD	[As a result, seven SNPs were significantly associated with PD, which were located in or adjacent to genes including PKP1, PLEKHG1, TMEM16B, CALCOCO1, SDK2 and CLU (or APO-J).]	0.002367032	2009	LOC105379341	8	27595330	G	A
rs1800855	20023595	886	CCKAR	umls:C0030319	BeFree	None of the other variations found were associated with PD, but a 2-marker haplotype (rs1800855/rs1800857) in the CCKAR gene protected women against PD (P=0.004).	0.013006804	2010	CCKAR	4	26489495	A	T
rs1800857	20023595	886	CCKAR	umls:C0030319	BeFree	None of the other variations found were associated with PD, but a 2-marker haplotype (rs1800855/rs1800857) in the CCKAR gene protected women against PD (P=0.004).	0.013006804	2010	CCKAR	4	26489489	A	G
rs2103868	19165232	27242	TNFRSF21	umls:C0030319	GAD	[Genome-wide association study of panic disorder in the Japanese population.]	0.002367032	2009	TNFRSF21	6	47262879	A	G
rs2823455	19165232	29761	USP25	umls:C0030319	GAD	[Genome-wide association study of panic disorder in the Japanese population.]	0.002367032	2009	NA	21	15696847	C	T
rs324420	23556448	2166	FAAH	umls:C0030319	BeFree	This study investigated the association of the Pro129Thr polymorphism of the FAAH gene with methamphetamine dependence, methamphetamine-induced psychosis, manic episodes and panic disorder in a Malaysian population.	0.000271442	2013	FAAH	1	46405089	C	A
rs324981	23680103	594857	NPS	umls:C0030319	BeFree	A coding variation (Asn107Ile) of the NPS receptor gene (NPSR1) was associated with panic disorder and schizophrenia.	0.002171535	2014	NPSR1;NPSR1-AS1	7	34778501	A	T
rs324981	24331455	594857	NPS	umls:C0030319	BeFree	Neuropeptide S is involved in anxiety and arousal modulation, and the functional polymorphism Asn107Ile (rs324981, A > T) of the neuropeptide S receptor gene (NPSR1) is associated with panic disorder and anxiety/fear-related traits.	0.002171535	2015	NPSR1;NPSR1-AS1	7	34778501	A	T
rs324981	24331455	387129	NPSR1	umls:C0030319	BeFree	Neuropeptide S is involved in anxiety and arousal modulation, and the functional polymorphism Asn107Ile (rs324981, A > T) of the neuropeptide S receptor gene (NPSR1) is associated with panic disorder and anxiety/fear-related traits.	0.001900093	2015	NPSR1;NPSR1-AS1	7	34778501	A	T
rs324981	23680103	387129	NPSR1	umls:C0030319	BeFree	A coding variation (Asn107Ile) of the NPS receptor gene (NPSR1) was associated with panic disorder and schizophrenia.	0.001900093	2014	NPSR1;NPSR1-AS1	7	34778501	A	T
rs324981	21525857	387129	NPSR1	umls:C0030319	BeFree	Recently, a functional polymorphism in the NPSR gene (rs324981 A/T) has been associated with panic disorder and anxiety sensitivity.	0.001900093	2011	NPSR1;NPSR1-AS1	7	34778501	A	T
rs3749380	19165232	2917	GRM7	umls:C0030319	GAD	[Genome-wide association study of panic disorder in the Japanese population.]	0.002367032	2009	GRM7	3	6861610	C	T
rs3816995	19165232	54549	SDK2	umls:C0030319	GWASCAT	As a result, seven SNPs were significantly associated with PD, which were located in or adjacent to genes including PKP1, PLEKHG1, TMEM16B, CALCOCO1, SDK2 and CLU (or APO-J).	0.122367032	2009	SDK2	17	73339121	G	A
rs3816995	19165232	54549	SDK2	umls:C0030319	GAD	[As a result, seven SNPs were significantly associated with PD, which were located in or adjacent to genes including PKP1, PLEKHG1, TMEM16B, CALCOCO1, SDK2 and CLU (or APO-J).]	0.122367032	2009	SDK2	17	73339121	G	A
rs386572987	16352396	2739	GLO1	umls:C0030319	BeFree	Association analysis of the functional Ala111Glu polymorphism of the glyoxalase I gene in panic disorder.	0.005362824	2006	NA	NA	NA	NA	NA
rs386602118	15118353	627	BDNF	umls:C0030319	BeFree	Association study of a brain-derived neurotrophic factor (Val66Met) genetic polymorphism and panic disorder.	0.001900093	2004	NA	NA	NA	NA	NA
rs386602276	15182959	3356	HTR2A	umls:C0030319	BeFree	No significant transmission disequilibrium was observed between the alleles of the T102C 5-HT2A receptor gene polymorphism and panic disorder, nor was a significant excess of either allele found in the case control analysis.	0.019726837	2004	NA	NA	NA	NA	NA
rs386602276	11444684	3356	HTR2A	umls:C0030319	BeFree	The authors tested for association of the 5-HT2A receptor polymorphism (T102C) and the intron 7 tryptophan hydroxylase (TPH) polymorphism (A218C) among 176 alcohol dependent patients, 35 patients with panic disorder, 50 patients with generalized anxiety disorder, 55 patients with narcolepsy and 87 healthy controls.	0.019726837	2001	NA	NA	NA	NA	NA
rs386602276	18436425	3356	HTR2A	umls:C0030319	BeFree	This result suggests that 5HTR2A 1438A/G and 102T/C polymorphic regions can be associated with the phenotype or the pathogenesis of panic disorder.	0.019726837	2008	NA	NA	NA	NA	NA
rs4570625	23552096	121278	TPH2	umls:C0030319	BeFree	In this study involving 64 individuals, we examined the associations between prefrontal cortical GABA concentration and 12 single nucleotide polymorphisms (SNPs) spanning the TPH2 gene, including rs4570625 (-703 G/T SNP), a potentially functional TPH2 polymorphism that has been associated with decreased TPH2 mRNA expression and panic disorder.	0.013549688	2014	TPH2	12	71938143	G	T
rs4680	20048750	1312	COMT	umls:C0030319	BeFree	Only Val158Met polymorphism of the catechol-O-methyltransferase gene has been implicated in susceptibility to PD by several studies in independent samples and confirmed in a recent meta-analysis.	0.162449467	2010	COMT;MIR4761	22	19963748	G	A
rs4680	24852514	1312	COMT	umls:C0030319	BeFree	Gender-specific association between the COMT Val158Met polymorphism and openness to experience in panic disorder patients.	0.162449467	2014	COMT;MIR4761	22	19963748	G	A
rs4680	18832011	3356	HTR2A	umls:C0030319	BeFree	Nine gene-candidates, including 5-HTTLPR, MAO-A VNTR, TPH2 rs1386494, 5-HTR1A -1019C-G, 5-HTR2A 102T-C, CCKR1 246G-A, CCKR2 -215C-A, DRD1 -94G-A and COMT Val158Met, were selected for genotyping based on previous positive findings from genetic association studies in PD.	0.019726837	2008	COMT;MIR4761	22	19963748	G	A
rs4680	18832011	1312	COMT	umls:C0030319	BeFree	Nine gene-candidates, including 5-HTTLPR, MAO-A VNTR, TPH2 rs1386494, 5-HTR1A -1019C-G, 5-HTR2A 102T-C, CCKR1 246G-A, CCKR2 -215C-A, DRD1 -94G-A and COMT Val158Met, were selected for genotyping based on previous positive findings from genetic association studies in PD.	0.162449467	2008	COMT;MIR4761	22	19963748	G	A
rs4680	23141115	1312	COMT	umls:C0030319	BeFree	The effects of the catechol-O-methyltransferase val158met polymorphism on white matter connectivity in patients with panic disorder.	0.162449467	2012	COMT;MIR4761	22	19963748	G	A
rs4680	19900710	1312	COMT	umls:C0030319	BeFree	Sympathetic nervous function and the effect of the catechol-O-methyltransferase Val(158)Met polymorphism in patients with panic disorder.	0.162449467	2010	COMT;MIR4761	22	19963748	G	A
rs4680	19429001	1312	COMT	umls:C0030319	BeFree	Asymmetry of prefrontal cortex activities and catechol-O-methyltransferase Val158Met genotype in patients with panic disorder during a verbal fluency task: near-infrared spectroscopy study.	0.162449467	2009	COMT;MIR4761	22	19963748	G	A
rs4680	20457471	1312	COMT	umls:C0030319	BeFree	Association between the catechol-O-methyltransferase Val158Met polymorphism and panic disorder: a replication.	0.162449467	2009	COMT;MIR4761	22	19963748	G	A
rs4680	17357147	1312	COMT	umls:C0030319	BeFree	Meta-analysis of COMT val158met in panic disorder: ethnic heterogeneity and gender specificity.	0.162449467	2007	COMT;MIR4761	22	19963748	G	A
rs4680	18440204	1312	COMT	umls:C0030319	BeFree	Influence of the catechol-O-methyltransferase val158met genotype on amygdala and prefrontal cortex emotional processing in panic disorder.	0.162449467	2008	COMT;MIR4761	22	19963748	G	A
rs4702982	19165232	345757	FAM174A	umls:C0030319	GAD	[Genome-wide association study of panic disorder in the Japanese population.]	0.002367032	2009	NA	5	100655944	C	T
rs4746	16352396	2739	GLO1	umls:C0030319	BeFree	Association analysis of the functional Ala111Glu polymorphism of the glyoxalase I gene in panic disorder.	0.005362824	2006	GLO1	6	38682852	T	G
rs5751876	20334879	135	ADORA2A	umls:C0030319	BeFree	A variant within the corresponding ADORA2A gene (rs5751876) increased the risk for panic disorder (PD), for elevated anxiety during challenge tests in healthy probands and for anxiety-related arousal in blood-injury phobia.	0.134178448	2010	ADORA2A;ADORA2A-AS1;SPECC1L-ADORA2A	22	24441333	T	C
rs5751876	22940476	135	ADORA2A	umls:C0030319	BeFree	The complex pathogenesis of anxiety and panic disorder in particular has been suggested to be influenced by genetic factors such as the adenosine A2A receptor gene (ADORA2A) 1976T>C polymorphism (rs5751876) as well as neuropsychological factors such as early information processing deficits.	0.134178448	2013	ADORA2A;ADORA2A-AS1;SPECC1L-ADORA2A	22	24441333	T	C
rs6295	21688171	6532	SLC6A4	umls:C0030319	BeFree	The present study revealed that plasma concentration of PAX, 5-HTTLPR genotype, -1019C/G 5-HT(1A) genotype, PAS score at baseline, and adverse effects may influence the therapeutic response to PAX in patients with PD.	0.045211374	2011	HTR1A	5	63962738	C	G
rs6295	16316476	3350	HTR1A	umls:C0030319	BeFree	Association of the functional -1019C/G 5-HT1A polymorphism with prefrontal cortex and amygdala activation measured with 3 T fMRI in panic disorder.	0.100541163	2006	HTR1A	5	63962738	C	G
rs6295	21688171	3350	HTR1A	umls:C0030319	BeFree	The present study revealed that plasma concentration of PAX, 5-HTTLPR genotype, -1019C/G 5-HT(1A) genotype, PAS score at baseline, and adverse effects may influence the therapeutic response to PAX in patients with PD.	0.100541163	2011	HTR1A	5	63962738	C	G
rs6296	15670397	3351	HTR1B	umls:C0030319	BeFree	In the present case-control study we investigated possible associations between PD phenotype and five candidate polymorphisms including 5-HT transporter (5-HTTLPR and VNTR), monoamine oxidase A (MAOA promoter region), tryptophan hydroxylase 1 (TPH1 218A/C) and 5-HT1B receptor (5-HT1BR 861G/C) genes.	0.002638474	2005	HTR1B;LOC105377864	6	77462543	C	G
rs6296	15670397	6532	SLC6A4	umls:C0030319	BeFree	In the present case-control study we investigated possible associations between PD phenotype and five candidate polymorphisms including 5-HT transporter (5-HTTLPR and VNTR), monoamine oxidase A (MAOA promoter region), tryptophan hydroxylase 1 (TPH1 218A/C) and 5-HT1B receptor (5-HT1BR 861G/C) genes.	0.045211374	2005	HTR1B;LOC105377864	6	77462543	C	G
rs6313	18436425	3356	HTR2A	umls:C0030319	BeFree	This result suggests that 5HTR2A 1438A/G and 102T/C polymorphic regions can be associated with the phenotype or the pathogenesis of panic disorder.	0.019726837	2008	HTR2A	13	46895805	G	A
rs6313	15182959	3356	HTR2A	umls:C0030319	BeFree	No significant transmission disequilibrium was observed between the alleles of the T102C 5-HT2A receptor gene polymorphism and panic disorder, nor was a significant excess of either allele found in the case control analysis.	0.019726837	2004	HTR2A	13	46895805	G	A
rs6313	11444684	3356	HTR2A	umls:C0030319	BeFree	The authors tested for association of the 5-HT2A receptor polymorphism (T102C) and the intron 7 tryptophan hydroxylase (TPH) polymorphism (A218C) among 176 alcohol dependent patients, 35 patients with panic disorder, 50 patients with generalized anxiety disorder, 55 patients with narcolepsy and 87 healthy controls.	0.019726837	2001	HTR2A	13	46895805	G	A
rs7299940	19165232	5901	RAN	umls:C0030319	GAD	[Genome-wide association study of panic disorder in the Japanese population.]	0.002367032	2009	NA	12	130906209	C	G
rs75634836	18832011	3356	HTR2A	umls:C0030319	BeFree	Nine gene-candidates, including 5-HTTLPR, MAO-A VNTR, TPH2 rs1386494, 5-HTR1A -1019C-G, 5-HTR2A 102T-C, CCKR1 246G-A, CCKR2 -215C-A, DRD1 -94G-A and COMT Val158Met, were selected for genotyping based on previous positive findings from genetic association studies in PD.	0.019726837	2008	HTR2A	13	46835532	C	A,T
rs75634836	18832011	1312	COMT	umls:C0030319	BeFree	Nine gene-candidates, including 5-HTTLPR, MAO-A VNTR, TPH2 rs1386494, 5-HTR1A -1019C-G, 5-HTR2A 102T-C, CCKR1 246G-A, CCKR2 -215C-A, DRD1 -94G-A and COMT Val158Met, were selected for genotyping based on previous positive findings from genetic association studies in PD.	0.162449467	2008	HTR2A	13	46835532	C	A,T
rs860554	19165232	5317	PKP1	umls:C0030319	GWASCAT	As a result, seven SNPs were significantly associated with PD, which were located in or adjacent to genes including PKP1, PLEKHG1, TMEM16B, CALCOCO1, SDK2 and CLU (or APO-J).	0.122367032	2009	PKP1	1	201293304	C	T,G
rs860554	19165232	5317	PKP1	umls:C0030319	GAD	[As a result, seven SNPs were significantly associated with PD, which were located in or adjacent to genes including PKP1, PLEKHG1, TMEM16B, CALCOCO1, SDK2 and CLU (or APO-J).]	0.122367032	2009	PKP1	1	201293304	C	T,G
rs9302001	19165232	101927284	LOC101927284	umls:C0030319	GWASCAT	Genome-wide association study of panic disorder in the Japanese population.	0.12	2009	LOC101927284	13	94811138	C	T
rs9372078	19165232	57480	PLEKHG1	umls:C0030319	GAD	[As a result, seven SNPs were significantly associated with PD, which were located in or adjacent to genes including PKP1, PLEKHG1, TMEM16B, CALCOCO1, SDK2 and CLU (or APO-J).]	0.002367032	2009	NA	6	150592825	T	A
rs9372078	19165232	389434	IYD	umls:C0030319	GAD	[Genome-wide association study of panic disorder in the Japanese population.]	0.002367032	2009	NA	6	150592825	T	A
rs941184	19165232	57658	CALCOCO1	umls:C0030319	GAD	[As a result, seven SNPs were significantly associated with PD, which were located in or adjacent to genes including PKP1, PLEKHG1, TMEM16B, CALCOCO1, SDK2 and CLU (or APO-J).]	0.122367032	2009	CALCOCO1	12	53720374	C	T
rs941184	19165232	57658	CALCOCO1	umls:C0030319	GWASCAT	As a result, seven SNPs were significantly associated with PD, which were located in or adjacent to genes including PKP1, PLEKHG1, TMEM16B, CALCOCO1, SDK2 and CLU (or APO-J).	0.122367032	2009	CALCOCO1	12	53720374	C	T
rs945032	19086053	624	BDKRB2	umls:C0030319	BeFree	Remarkably, a functional SNP, rs945032, located in the promoter region of the bradykinin receptor B2 gene (BDKRB2) was associated to three disorders (panic disorder, substance abuse, and bipolar disorder), and two additional BDKRB2 SNPs to obsessive-compulsive disorder and major depression, providing evidence for common variants of susceptibility to several related psychiatric disorders.	0.000271442	2009	BDKRB2	14	96204324	T	C

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:392)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
1	3002072	rs2981884	A	G	rs2981884	19165232	9.40E-06	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	PRDM16
1	6033973	rs4908458	C	T	rs4908458	23149450	0.000085	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
1	9005320	rs1409147	A	G	rs1409147	23149450	0.0000063	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
1	23504795	rs2806561	A	G	rs2806561	19165232	6.89E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	NA
1	38630862	rs6693777	A	G	rs6693777	19165232	3.72E-06	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	A,G	NA
1	42623672	rs11210604	T	G	rs11210604	19165232	3.01E-07	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	NA
1	50808295	rs6657279	A	G	rs6657279	19165232	5.90E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	NA
1	111237685	rs12061304	A	G	rs12061304	19165232	1.00E-06	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	NA
1	111237685	rs12061304	A	G	rs12061304	23149450	0.0000613	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
1	111240982	rs11102149	G	C	rs11102149	19165232	3.14E-06	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	NA
1	111240982	rs11102149	G	C	rs11102149	23149450	0.0000615	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
1	150463772	rs7542068	C	G	rs7542068	19165232	9.14E-06	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	TARS2
1	157767362	rs12132140	C	T	rs12132140	19165232	4.32E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	FCRL1
1	165651502	rs1913844	G	C	rs1913844	23149450	0.0000699	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
1	167059336	rs2281964	C	T	rs2281964	23149450	0.00000639	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
1	172973645	rs2092357	G	A	rs2092357	19165232	9.45E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	NA
1	193584062	rs6668266	T	C	rs6668266	23149450	0.0000306	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
1	201262432	rs860554	C	T	rs860554	19165232	5.00E-08	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	PKP1
1	224777150	rs16849891	A	G	rs16849891	19165232	1.09E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	A	NA
1	237215263	rs4659488	T	C	rs4659488	23149450	0.0000478	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
1	237216056	rs1124814	A	G	rs1124814	23149450	0.0000436	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
1	248349215	rs4615870	C	T	rs4615870	19165232	4.29E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	NA
2	36098961	rs1401775	T	C	rs1401775	19165232	8.83E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	NA
2	36620953	rs12466450	C	T	rs12466450	20368705	1.00E-04	Panic disorder	NA	NA	216 European ancestry cases; 222 European ancestry controls	European(438)	ALL(438)	EUR(438)	ALL(438)	Anxiety spectrum disorders	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	NA	NA	NA	NA	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	CRIM1
2	37527164	rs6754376	A	G	rs6754376	19165232	6.91E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	PRKD3
2	49790063	rs1995172	C	T	rs1995172	23149450	0.0000195	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
2	52599360	rs17788159	T	C	rs17788159	23149450	0.0000604	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
2	53954681	rs6705712	C	G	rs6705712	23149450	0.0000569	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
2	53958136	rs10188142	C	T	rs10188142	23149450	0.0000554	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
2	53965389	rs3821081	G	A	rs3821081	23149450	0.0000803	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
2	53972693	rs3770393	G	A	rs3770393	23149450	0.0000749	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
2	53974223	rs12613353	T	G	rs12613353	23149450	0.0000898	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
2	54018924	rs2542588	C	T	rs2542588	23149450	0.0000434	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
2	54056188	rs805438	T	A	rs805438	23149450	0.0000341	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
2	54056270	rs2080721	C	G	rs2080721	23149450	0.0000484	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
2	54056574	rs805439	C	T	rs805439	23149450	0.0000215	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
2	54058082	rs12617599	G	C,T	rs12617599	23149450	0.0000737	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
2	59694749	rs13018470	C	T	rs13018470	23149450	0.0000683	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
2	76408283	rs13417780	G	A	rs13417780	19165232	1.26E-06	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	A	NA
2	80182604	rs6745989	G	A	rs6745989	19165232	5.41E-06	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	A	CTNNA2
2	107210805	rs13017273	A	G	rs13017273	23149450	0.0000872	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
2	107241221	rs17033012	A	G	rs17033012	23149450	0.000045	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
2	107258436	rs17033088	T	G	rs17033088	23149450	0.0000814	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
2	119814011	rs17011073	A	G	rs17011073	19165232	6.27E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	A	NA
2	127457760	rs7597899	T	C	rs7597899	19165232	9.64E-06	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	NA
2	127659981	rs6733840	T	C	rs6733840	19165232	6.02E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	NA
2	130547748	rs3990701	A	G	rs3990701	19165232	3.55E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	NA
2	141041323	rs11883474	T	G	rs11883474	19165232	1.95E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	LRP1B
2	148683919	rs12620026	A	T	rs12620026	19165232	4.63E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	ACVR2A
2	174850890	rs16862246	G	A	rs16862246	23149450	0.0000685	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
2	209643445	rs11896599	T	A	rs11896599	19165232	3.70E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	NA
2	219823497	rs359983	G	A	rs359983	23149450	0.0000423	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
2	219840891	rs359965	G	A	rs359965	23149450	0.0000494	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
2	232091948	rs6437008	C	G	rs6437008	23149450	0.000096	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
2	234953978	rs7593927	T	G	rs7593927	23149450	0.0000917	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
3	2169803	rs4129976	T	C	rs4129976	23149450	0.00000712	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
3	2194392	rs2729017	C	A,T	rs2729017	23149450	0.0000343	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
3	3000908	rs751056	A	G	rs751056	19165232	9.92E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	CNTN4
3	3000908	rs751056	A	G	rs751056	23149450	0.0000527	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
3	6903297	rs3749380	C	T	rs3749380	19165232	2.00E-06	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	GRM7
3	45145019	rs4579052	G	T	rs4579052	23149450	0.0000557	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
3	60585756	rs7617530	G	A	rs7617530	20368705	1.00E-05	Panic disorder	NA	NA	216 European ancestry cases; 222 European ancestry controls	European(438)	ALL(438)	EUR(438)	ALL(438)	Anxiety spectrum disorders	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	NA	NA	NA	NA	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	FHIT
3	100914154	rs2317582	G	C	rs2317582	23149450	0.0000128	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
3	126227185	rs16837531	G	A	rs16837531	23149450	0.0000302	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
3	134476223	rs1877962	A	C	rs1877962	19165232	3.20E-06	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	A	NA
3	149279595	rs16861999	T	G	rs16861999	19165232	5.46E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	WWTR1
3	153788222	rs938989	A	G	rs938989	19165232	4.42E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	ARHGEF26-AS1
3	159056759	rs9290036	C	T	rs9290036	23149450	0.0000216	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
3	159074327	rs9823822	G	A	rs9823822	23149450	0.0000239	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
3	160223032	rs721022	C	T	rs721022	20368705	1.00E-05	Panic disorder	NA	NA	216 European ancestry cases; 222 European ancestry controls	European(438)	ALL(438)	EUR(438)	ALL(438)	Anxiety spectrum disorders	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	NA	NA	NA	NA	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	KPNA4
3	160685788	rs2121721	T	C	rs2121721	23149450	0.0000905	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
3	182243381	rs12486463	T	A	rs12486463	23149450	0.0000218	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
3	182245072	rs1457567	G	A	rs1457567	23149450	0.0000141	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
3	182252137	rs7613189	G	A	rs7613189	23149450	0.0000107	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
3	182252604	rs7615678	G	T	rs7615678	23149450	0.00001	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
3	182255337	rs7622673	G	A	rs7622673	23149450	0.0000174	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
3	184363909	rs4635684	T	C	rs4635684	23149450	0.0000155	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
3	184366735	rs10937184	C	T	rs10937184	23149450	0.0000173	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
3	184380746	rs9855937	T	A	rs9855937	23149450	0.0000283	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
3	184384129	rs4234607	C	G	rs4234607	23149450	0.0000592	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
3	188566306	rs9861473	A	G	rs9861473	23149450	0.0000588	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
3	193697644	rs2367937	G	A	rs2367937	23149450	0.0000297	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
4	23884711	rs3796407	G	A	rs3796407	21871609	4.20E-04	Anxiety-spectrum phenotypes (anxiety disorders, neuroticism, and major depression)	NA	NA	1227 European ancestry individuals	European(1227)	ALL(1227)	EUR(1227)	ALL(1227)	Anxiety spectrum disorders	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	NA	NA	NA	NA	Panic disorder	NA	Twin Study	Research Support, N.I.H., Extramural	Meta-Analysis
4	31142938	rs16884410	C	T	rs16884410	23149450	0.0000407	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
4	31148287	rs11567	C	T	rs11567	23149450	0.00004	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
4	31154607	rs10517224	T	C	rs10517224	23149450	0.0000433	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
4	31156148	rs10517221	T	C	rs10517221	23149450	0.0000447	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
4	31158565	rs1353854	T	A,C,G	rs1353854	23149450	0.0000485	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
4	31158655	rs16884487	G	A,C	rs16884487	23149450	0.0000275	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
4	38797876	rs4624663	T	C	rs4624663	19165232	5.87E-06	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	A	TLR1
4	84539360	rs781430	G	A	rs781430	19165232	4.24E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	NA
4	84902522	rs3913795	C	T	rs3913795	23149450	0.0000678	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
4	102136173	rs3804375	G	A	rs3804375	19165232	3.97E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	PPP3CA
4	107455176	rs17357756	A	C	rs17357756	19165232	2.08E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	A	NA
4	120587896	rs17051362	T	G	rs17051362	19165232	7.14E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	NA
4	163211495	rs4691041	G	A	rs4691041	19165232	7.16E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G,A	NA
4	169972311	rs10009678	T	C	rs10009678	23149450	0.0000309	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
4	182614559	rs2309573	T	G	rs2309573	23149450	0.0000308	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
4	186913109	rs830838	C	T	rs830838	23149450	0.0000326	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
5	5788380	rs3891830	G	A	rs3891830	23149450	0.0000542	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
5	21232485	rs2172239	G	C	rs2172239	19165232	2.79E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	NA
5	29226086	rs7726399	C	A	rs7726399	23149450	0.0000248	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
5	31872998	rs6882892	T	G	rs6882892	23149450	0.0000945	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
5	40522212	rs10941516	A	G	rs10941516	23149450	0.0000611	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
5	40531620	rs2202528	G	C	rs2202528	23149450	0.0000392	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
5	67221332	rs4976138	C	G	rs4976138	19165232	3.27E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	NA
5	70974576	rs281128	G	A,C,T	rs281128	23149450	0.0000623	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
5	80535750	rs16876403	C	T	rs16876403	23149450	0.0000743	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
5	80538143	rs2277037	G	A	rs2277037	23149450	0.0000997	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
5	80612629	rs12514420	T	C	rs12514420	23149450	0.0000242	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
5	80616472	rs6868743	G	T	rs6868743	23149450	0.000051	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
5	80619534	rs4502795	T	A	rs4502795	23149450	0.0000604	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
5	98428184	rs7716372	A	G	rs7716372	19165232	7.65E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	A	NA
5	99991648	rs4702982	C	T	rs4702982	19165232	6.00E-06	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	NA
5	109044067	rs6877440	T	C	rs6877440	19165232	6.27E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	MAN2A1
5	112965145	rs6889348	A	G	rs6889348	19165232	7.27E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	A	NA
5	135327555	rs13356494	C	G	rs13356494	19165232	4.05E-07	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	NA
5	150828004	rs729057	T	G	rs729057	23149450	0.000046	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
5	167831555	rs11134510	C	T	rs11134510	23149450	0.0000202	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
5	167831633	rs4976549	G	T	rs4976549	23149450	0.0000196	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
5	177380624	rs11741476	T	G	rs11741476	19165232	1.52E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	NA	NA
5	178425192	rs1969025	G	A	rs1969025	23149450	0.0000201	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
6	2954557	rs2295767	C	T	rs2295767	19165232	6.58E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	SERPINB6
6	5883721	rs17141353	A	G	rs17141353	23149450	0.0000549	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
6	10369675	rs10484886	C	T	rs10484886	23149450	0.0000998	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
6	13529708	rs2560770	A	G	rs2560770	19165232	6.54E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T,C	NA
6	46541261	rs699945	G	T	rs699945	19165232	2.36E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	CYP39A1
6	47230615	rs2103868	A	G	rs2103868	19165232	5.00E-06	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	TNFRSF21
6	71878869	rs1418688	A	G	rs1418688	19165232	9.33E-08	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	NA
6	75129384	rs1853182	T	A	rs1853182	19165232	9.76E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	A	NA
6	99549296	rs17059155	G	T	rs17059155	23149450	0.0000155	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
6	105745188	rs1190053	G	A	rs1190053	19165232	8.48E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	PREP
6	110897030	rs4512259	T	C	rs4512259	23149450	0.0000684	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
6	110902843	rs9374185	T	C	rs9374185	23149450	0.0000317	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
6	110932032	rs1543991	T	C	rs1543991	23149450	0.0000486	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
6	110946811	rs9386927	A	G	rs9386927	23149450	0.0000655	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
6	110981076	rs1949817	T	A	rs1949817	23149450	0.0000732	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
6	111064499	rs4383853	C	T	rs4383853	23149450	0.0000256	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
6	111106135	rs802660	C	T	rs802660	23149450	0.0000381	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
6	111106687	rs802661	G	T	rs802661	23149450	0.0000279	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
6	111171882	rs802669	G	A	rs802669	23149450	0.0000122	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
6	150913961	rs9372078	T	A	rs9372078	19165232	5.00E-07	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	A	NA
6	154262894	rs1885629	T	C	rs1885629	23149450	0.0000421	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
6	154262938	rs1885628	G	A	rs1885628	23149450	0.0000434	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
6	154266022	rs17084721	A	G	rs17084721	23149450	0.0000392	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
6	154266598	rs9397672	C	A	rs9397672	23149450	0.0000363	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
6	154266709	rs9397673	A	G	rs9397673	23149450	0.0000339	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
6	154267000	rs9397674	C	T	rs9397674	23149450	0.0000323	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
6	154267147	rs2169411	A	G	rs2169411	23149450	0.0000319	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
6	154268544	rs1033816	C	T	rs1033816	23149450	0.0000352	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
6	154269510	rs7758009	T	C	rs7758009	23149450	0.0000364	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
6	154275074	rs9384167	C	T	rs9384167	23149450	0.000036	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
6	154278384	rs12174208	G	T	rs12174208	23149450	0.0000347	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
6	154281391	rs9384168	C	A	rs9384168	23149450	0.0000338	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
6	154288583	rs11966947	G	A	rs11966947	23149450	0.0000216	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
6	154295073	rs7760028	A	G	rs7760028	23149450	0.000028	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
7	21195371	rs12700260	C	T	rs12700260	23149450	0.000091	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
7	39117624	rs11769233	T	A	rs11769233	23149450	0.0000503	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
7	78446898	rs1209400	T	C	rs1209400	23149450	0.0000727	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
7	78455169	rs489403	A	G	rs489403	23149450	0.0000801	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
7	78456148	rs519514	C	T	rs519514	23149450	0.0000817	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
7	78456168	rs508733	G	A	rs508733	23149450	0.0000118	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
7	110432527	rs12537293	G	A	rs12537293	19165232	8.58E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	IMMP2L
7	113008273	rs17498088	G	A	rs17498088	23149450	0.0000597	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
7	132441715	rs10215173	G	A	rs10215173	19165232	2.52E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	A	NA
7	143203582	rs2966701	A	G	rs2966701	23149450	0.0000864	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
7	156915086	rs6459728	G	A	rs6459728	19165232	2.43E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	NA
8	6483482	rs2912057	C	T	rs2912057	23149450	0.0000112	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
8	6488505	rs2911968	T	C	rs2911968	23149450	0.00000505	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
8	6488921	rs3020265	G	A	rs3020265	23149450	0.00000936	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
8	6490665	rs2912065	T	G	rs2912065	23149450	0.0000408	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
8	9103134	rs17149618	A	G	rs17149618	23149450	0.0000203	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
8	14364923	rs10216809	C	T	rs10216809	19165232	1.20E-08	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T,C	SGCZ
8	18013316	rs2078711	C	T	rs2078711	19165232	4.43E-06	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	NA
8	25002551	rs6557819	T	C	rs6557819	19165232	8.02E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	NA
8	27452847	rs17466684	G	A	rs17466684	19165232	7.00E-07	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	NA
8	57347126	rs2196586	T	C	rs2196586	23149450	0.00000792	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
8	57355545	rs6474063	C	T	rs6474063	23149450	0.0000569	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
8	57390386	rs2016795	A	G	rs2016795	19165232	7.82E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	NA
8	57393286	rs2118261	G	A	rs2118261	19165232	3.95E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	NA
8	57393286	rs2118261	G	A	rs2118261	23149450	0.0000758	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
8	57418332	rs2055984	T	C	rs2055984	23149450	0.000047	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
8	82033527	rs10504731	T	C	rs10504731	19165232	1.51E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	NA
8	126795581	rs6470380	A	G	rs6470380	23149450	0.0000414	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
8	142583871	rs607831	C	T	rs607831	23149450	0.0000226	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
9	663644	rs2361107	C	G	rs2361107	23149450	0.0000842	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
9	1325139	rs7875774	T	G	rs7875774	19165232	7.63E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	NA
9	2160378	rs7032394	A	G	rs7032394	19165232	7.42E-06	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	A	SMARCA2
9	7162852	rs16925503	A	T	rs16925503	23149450	0.00000848	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
9	12182545	rs17260539	G	A	rs17260539	19165232	2.47E-07	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	NA
9	72362158	rs10511969	C	T	rs10511969	23149450	0.00000769	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
9	81930694	rs10867359	T	C	rs10867359	19165232	5.32E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	NA
9	121916856	rs230117	G	A	rs230117	19165232	6.84E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	NA
9	135398088	rs944805	C	T	rs944805	23149450	0.00000578	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
10	3550613	rs12264969	T	C	rs12264969	19165232	2.57E-06	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	NA
10	6731456	rs10508311	C	G	rs10508311	23149450	0.0000215	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
10	6738313	rs12573122	A	G	rs12573122	23149450	0.0000593	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
10	8691594	rs827411	C	A	rs827411	23149450	0.0000235	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
10	8700934	rs827392	A	G	rs827392	23149450	0.0000102	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
10	8708668	rs2483924	A	C	rs2483924	23149450	0.0000479	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
10	8711723	rs4749806	C	T	rs4749806	23149450	0.0000204	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
10	13762786	rs10796116	A	G	rs10796116	23149450	0.0000999	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
10	19596431	rs11009391	C	G	rs11009391	23149450	0.0000314	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
10	24967092	rs7070456	C	T	rs7070456	19165232	8.15E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	ARHGAP21
10	80080664	rs16935812	C	T	rs16935812	23149450	0.0000418	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
10	80080866	rs7920472	C	T	rs7920472	23149450	0.000037	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
10	99596664	rs4300338	G	C	rs4300338	19165232	9.15E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	LOC100505561
10	113241074	rs4917611	C	T	rs4917611	23149450	0.0000223	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
11	15521553	rs6486251	T	G	rs6486251	23149450	0.0000844	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
11	29197113	rs1463706	C	G	rs1463706	23149450	0.000041	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
11	29198384	rs2452144	G	A	rs2452144	23149450	0.00000458	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
11	45200619	rs16938184	G	C	rs16938184	19165232	3.03E-07	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	PRDM11
11	60534901	rs4939450	G	C	rs4939450	23149450	0.0000458	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
11	98599094	rs12577421	C	G	rs12577421	23149450	0.0000699	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
11	100498729	rs10894993	T	G	rs10894993	19165232	5.64E-07	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	NA
11	116168614	rs12420498	T	A	rs12420498	19165232	5.20E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	A	NA
11	117959372	rs2276435	G	A	rs2276435	23149450	0.0000974	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
12	5797101	rs12579350	G	A	rs12579350	19165232	4.00E-09	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	ANO2
12	17881386	rs7973547	C	A	rs7973547	23149450	0.0000711	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
12	41723120	rs11180828	A	G	rs11180828	19165232	7.88E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	PDZRN4
12	41723120	rs11180828	A	G	rs11180828	23149450	0.0000442	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
12	43160825	rs2731006	C	T	rs2731006	19165232	4.00E-06	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	NA
12	43181274	rs2731000	C	T	rs2731000	19165232	4.81E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	NA
12	43206476	rs12227600	C	T	rs12227600	19165232	2.63E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	NA
12	45357804	rs10880717	T	C	rs10880717	23149450	0.0000181	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
12	54114158	rs941184	C	T	rs941184	19165232	3.00E-07	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	CALCOCO1
12	58872899	rs10783899	T	C	rs10783899	23149450	0.0000982	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
12	58874881	rs11172630	C	T	rs11172630	23149450	0.0000751	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
12	58876062	rs6581196	A	C	rs6581196	23149450	0.0000888	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
12	60608389	rs7301616	C	T	rs7301616	19165232	9.21E-07	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	NA
12	70681604	rs12230432	T	C	rs12230432	23149450	0.0000322	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
12	106053310	rs4145262	C	A	rs4145262	23149450	0.000000324	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
12	114743644	rs2114326	C	A	rs2114326	23149450	0.0000497	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
12	126107480	rs11610341	C	T	rs11610341	19165232	1.84E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	TMEM132B
12	126381317	rs7980248	T	C	rs7980248	23149450	0.0000147	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
12	126406271	rs11058396	T	A	rs11058396	23149450	0.0000196	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
12	126415017	rs225518	G	A	rs225518	23149450	0.0000689	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
12	129786584	rs900256	C	T	rs900256	20368705	1.40E-06	Anxiety severity scores	NA	NA	216 European ancestry cases; 222 European ancestry controls	European(438)	ALL(438)	EUR(438)	ALL(438)	Anxiety spectrum disorders	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	NA	NA	NA	NA	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	TMEM132D
12	129786584	rs900256	C	T	rs900256	20368705	3.00E-04	Severity of anxiety symptoms (Panic disorder)	NA	NA	216 European ancestry cases; 222 European ancestry controls	European(438)	ALL(438)	EUR(438)	ALL(438)	Anxiety spectrum disorders	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	NA	NA	NA	NA	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	TMEM132D
12	129791496	rs879560	C	T	rs879560	20368705	5.00E-07	Anxiety severity scores	NA	NA	216 European ancestry cases; 222 European ancestry controls	European(438)	ALL(438)	EUR(438)	ALL(438)	Anxiety spectrum disorders	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	NA	NA	NA	NA	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	TMEM132D
12	129791496	rs879560	C	T	rs879560	20368705	6.00E-04	Severity of anxiety symptoms (Panic disorder)	NA	NA	216 European ancestry cases; 222 European ancestry controls	European(438)	ALL(438)	EUR(438)	ALL(438)	Anxiety spectrum disorders	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	NA	NA	NA	NA	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	TMEM132D
12	129812096	rs10847832	A	G	rs10847832	20368705	7.00E-04	Severity of anxiety symptoms (Panic disorder)	NA	NA	216 European ancestry cases; 222 European ancestry controls	European(438)	ALL(438)	EUR(438)	ALL(438)	Anxiety spectrum disorders	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	NA	NA	NA	NA	Panic disorder	NA	Research Support, Non-U.S. Gov't	A	TMEM132D
12	129955359	rs7309727	T	C	rs7309727	20368705	4.87E-08	Panic disorder	NA	NA	216 European ancestry cases; 222 European ancestry controls	European(438)	ALL(438)	EUR(438)	ALL(438)	Anxiety spectrum disorders	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	NA	NA	NA	NA	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	TMEM132D
12	129960197	rs11060369	A	C	rs11060369	20368705	7.63E-06	Panic disorder	NA	NA	216 European ancestry cases; 222 European ancestry controls	European(438)	ALL(438)	EUR(438)	ALL(438)	Anxiety spectrum disorders	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	NA	NA	NA	NA	Panic disorder	NA	Research Support, Non-U.S. Gov't	A	TMEM132D
12	131332099	rs10773829	G	A	rs10773829	19165232	4.41E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	A,G	NA
12	131390754	rs7299940	C	G	rs7299940	19165232	7.00E-06	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	NA
13	24296345	rs9507148	G	T	rs9507148	23149450	0.000088	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
13	24296862	rs7324557	A	G	rs7324557	23149450	0.0000355	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
13	60131564	rs1711792	G	C	rs1711792	23149450	0.000023	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
13	60140976	rs9563740	A	G	rs9563740	23149450	0.0000222	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
13	60141047	rs831207	C	T	rs831207	23149450	0.0000749	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
13	60153623	rs862728	G	C	rs862728	23149450	0.000023	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
13	60154144	rs831215	G	T	rs831215	23149450	0.0000229	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
13	60154768	rs573497	C	T	rs573497	23149450	0.0000229	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
13	60154787	rs670137	T	A	rs670137	23149450	0.0000226	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
13	60154822	rs574291	C	A	rs574291	23149450	0.0000226	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
13	60154897	rs669712	C	T	rs669712	23149450	0.0000226	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
13	60155039	rs669188	T	C	rs669188	23149450	0.0000226	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
13	60155344	rs489624	A	G	rs489624	23149450	0.0000225	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
13	60155445	rs667039	T	C	rs667039	23149450	0.0000224	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
13	60155513	rs491388	T	C	rs491388	23149450	0.0000223	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
13	60155600	rs666550	C	T	rs666550	23149450	0.0000222	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
13	60156070	rs654178	A	G	rs654178	23149450	0.0000222	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
13	60156754	rs640694	G	A	rs640694	23149450	0.0000221	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
13	60157175	rs527287	A	C	rs527287	23149450	0.000022	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
13	60157275	rs549227	C	A	rs549227	23149450	0.000022	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
13	60157813	rs1615781	T	C	rs1615781	23149450	0.0000219	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
13	60158264	rs579303	T	C	rs579303	23149450	0.0000217	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
13	60158729	rs473386	A	T	rs473386	23149450	0.0000216	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
13	60158815	rs473611	T	C	rs473611	23149450	0.0000216	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T,C
13	60158863	rs610696	A	T	rs610696	23149450	0.0000216	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
13	60158910	rs610640	G	T	rs610640	23149450	0.0000216	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
13	60159514	rs501448	C	T	rs501448	23149450	0.0000216	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
13	60159536	rs502140	G	T	rs502140	23149450	0.0000215	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
13	60159568	rs502229	A	C	rs502229	23149450	0.0000215	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
13	60159625	rs607560	T	C	rs607560	23149450	0.0000214	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
13	60159634	rs607546	A	G	rs607546	23149450	0.0000223	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
13	60159914	rs505095	T	C	rs505095	23149450	0.0000224	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
13	60160065	rs506806	G	A	rs506806	23149450	0.0000224	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
13	60160505	rs4609710	T	C	rs4609710	23149450	0.0000225	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
13	60160545	rs4482172	A	C	rs4482172	23149450	0.0000225	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
13	60160738	rs592255	G	A	rs592255	23149450	0.0000226	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
13	60161189	rs670922	A	G	rs670922	23149450	0.0000225	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
13	60161305	rs559909	C	T	rs559909	23149450	0.0000227	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
13	60161554	rs562553	T	G	rs562553	23149450	0.0000227	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
13	60161927	rs565500	T	C	rs565500	23149450	0.0000227	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
13	60162048	rs1463449	A	G	rs1463449	23149450	0.0000226	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
13	60162503	rs936336	G	A	rs936336	23149450	0.0000227	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
13	60162598	rs936334	C	G	rs936334	23149450	0.0000221	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
13	60163668	rs571049	T	C	rs571049	23149450	0.0000408	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
13	60164223	rs486428	C	T	rs486428	23149450	0.0000219	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
13	60166033	rs545142	A	T	rs545142	23149450	0.0000152	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
13	60174337	rs677168	A	C	rs677168	23149450	0.0000222	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
13	60174482	rs676655	G	A	rs676655	23149450	0.0000223	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
13	60174814	rs496560	T	C	rs496560	23149450	0.0000227	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
13	60178077	rs4884343	A	G	rs4884343	23149450	0.0000228	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
13	60178824	rs492632	G	C	rs492632	23149450	0.0000233	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
13	95463392	rs9302001	C	T	rs9302001	19165232	3.00E-07	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	NA
13	95463392	rs9302001	C	T	rs9302001	23149450	0.000000226	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
13	105913681	rs9582972	C	T	rs9582972	19165232	1.14E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	NA
14	21820454	rs10872898	G	C	rs10872898	19165232	6.08E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	SUPT16H
14	22420837	rs2031069	C	T	rs2031069	23149450	0.0000274	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
14	22421388	rs2331471	G	A	rs2331471	23149450	0.0000439	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
14	22422976	rs12586624	C	T	rs12586624	23149450	0.000056	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
14	22427935	rs1040296	A	T	rs1040296	23149450	0.0000324	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
14	22428443	rs2331473	T	A	rs2331473	23149450	0.0000351	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
14	22428984	rs1040297	G	T	rs1040297	23149450	0.0000358	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
14	22429647	rs4982533	T	C	rs4982533	23149450	0.0000362	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
14	22430340	rs11157339	G	A	rs11157339	23149450	0.0000404	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
14	22433466	rs12589803	G	A	rs12589803	23149450	0.0000433	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
14	22434606	rs10872970	C	T	rs10872970	23149450	0.0000469	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
14	22445355	rs12587312	A	G	rs12587312	23149450	0.000048	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
14	23371611	rs17124097	T	C	rs17124097	19165232	3.17E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	RBM23
14	40223352	rs8020871	C	T	rs8020871	23149450	0.0000368	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
14	43433918	rs17113722	T	C	rs17113722	23149450	0.0000166	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
14	51865340	rs10498424	T	A	rs10498424	23149450	0.0000235	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
14	51865340	rs530874840	TAAG	T	rs10498424	23149450	0.0000235	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
14	56006169	rs8011732	A	G	rs8011732	23149450	0.0000235	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
14	56015498	rs4901589	G	A,C	rs4901589	23149450	0.0000113	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
14	56023822	rs942317	A	C	rs942317	23149450	0.0000576	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
14	56136562	rs3783654	C	A	rs3783654	23149450	0.0000487	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
14	56142480	rs3736877	A	G	rs3736877	23149450	0.0000488	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
14	56150151	rs1953356	A	G	rs1953356	23149450	0.000086	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
14	59334128	rs4901869	A	G	rs4901869	19165232	6.00E-06	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	A	NA
14	68257005	rs7143559	T	G	rs7143559	19165232	7.46E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	ZFYVE26
14	81789479	rs8013992	A	G	rs8013992	19165232	1.45E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	STON2
14	96589360	rs11160311	T	C	rs11160311	23149450	0.0000178	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
14	96597957	rs4905446	A	C	rs4905446	23149450	0.0000696	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
14	96635447	rs10144552	G	A	rs10144552	23149450	0.00000102	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
14	103717242	rs11160738	T	C	rs11160738	23149450	0.0000475	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
15	34221265	rs485191	C	T	rs485191	23149450	0.0000356	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
15	40655845	rs1898883	C	G	rs1898883	23149450	0.0000411	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
15	40658970	rs1992272	T	C	rs1992272	23149450	0.000024	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
15	45856592	rs755165	T	C	rs755165	19165232	3.00E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	NA
15	87168732	rs16977877	G	A	rs16977877	23149450	0.0000185	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
15	87169271	rs8040090	G	A	rs8040090	23149450	0.0000185	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
15	99053813	rs7170126	C	T	rs7170126	23149450	0.0000574	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
15	99572216	rs925234	C	T	rs925234	23149450	0.0000553	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
15	99573395	rs2663101	T	G	rs2663101	23149450	0.0000485	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
16	25121277	rs11642659	T	C	rs11642659	19165232	1.18E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	NA
16	64014002	rs879153	A	C	rs879153	19165232	2.71E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	A	NA
17	31989230	rs280039	C	T	rs280039	23149450	0.0000397	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
17	35057303	rs8079759	A	C	rs8079759	19165232	7.47E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	A	NA
17	48877899	rs16949303	G	A,C	rs16949303	19165232	2.64E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	NA
17	54612445	rs10515131	T	C	rs10515131	19165232	6.85E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	NA
17	57775463	rs16943799	T	C	rs16943799	19165232	9.85E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	PTRH2
17	65022159	rs2159211	T	C	rs2159211	23149450	0.0000479	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
17	68833326	rs9895016	C	T	rs9895016	23149450	0.0000491	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
17	68840462	rs2190551	A	T	rs2190551	23149450	0.0000306	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
17	68845035	rs978708	C	A	rs978708	23149450	0.0000494	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
17	68954153	rs12952980	G	A	rs12952980	19165232	1.70E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	NA
17	71335260	rs3816995	G	A	rs3816995	19165232	2.00E-07	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	SDK2
17	71335260	rs3816995	G	A	rs3816995	23149450	0.0000443	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
17	78779981	rs4969277	C	T	rs4969277	23149450	0.0000159	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
18	293519	rs8083730	G	A	rs8083730	23149450	0.0000566	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A,G
18	8922950	rs9952946	G	C	rs9952946	23149450	0.000011	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
18	27911115	rs4499314	C	T	rs4499314	19165232	8.11E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	NA
18	32373736	rs1383290	A	C	rs1383290	19165232	6.17E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	DTNA
18	45620052	rs12604363	C	A	rs12604363	23149450	0.0000848	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
18	73838971	rs10514202	C	T	rs10514202	23149450	0.0000536	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
18	73842356	rs12962858	C	T	rs12962858	23149450	0.0000652	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C,T
18	73850392	rs11660890	T	C	rs11660890	19165232	6.04E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	LOC339298
19	22814076	rs16999519	C	T	rs16999519	23149450	0.0000863	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
19	22909658	rs16999009	G	A	rs16999009	23149450	0.0000388	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
19	34010189	rs10415555	A	G	rs10415555	19165232	1.85E-07	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	A	PEPD
19	45699289	rs3848527	C	G	rs3848527	23149450	0.0000462	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
19	50223266	rs3810265	G	A	rs3810265	19165232	4.00E-06	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	NA
19	51166691	rs8101383	C	G	rs8101383	23149450	0.0000223	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
20	4169079	rs16989303	G	A	rs16989303	19165232	6.00E-06	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	NA
20	4716479	rs6037941	A	G	rs6037941	23149450	0.0000643	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
20	4749032	rs12480756	C	T	rs12480756	23149450	0.00000227	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
20	4749289	rs2422958	C	A	rs2422958	23149450	0.0000643	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
20	4757364	rs12625405	T	C	rs12625405	23149450	0.0000152	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
20	10637057	rs10485741	T	C	rs10485741	19165232	9.38E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	JAG1
20	10637057	rs34271232	T	TG	rs10485741	19165232	9.38E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	JAG1
20	32889704	rs819147	C	T	rs819147	23149450	0.00000422	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
20	42533424	rs4812755	T	A	rs4812755	19165232	7.80E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	T	NA
21	16993068	rs16987706	G	T	rs16987706	19165232	7.44E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	NA
21	17069166	rs2823455	C	T	rs2823455	19165232	9.00E-06	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	NA
21	21892531	rs7279330	A	G	rs7279330	19165232	3.35E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	A	NA
21	22931980	rs12482461	G	A	rs12482461	23149450	0.0000401	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
21	25148252	rs2040256	A	G	rs2040256	23149450	0.0000677	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
22	36533785	rs132617	C	T	rs132617	19165232	7.16E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	C	NA
22	36533785	rs132617	C	T	rs132617	23149450	0.0000575	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	C
X	4815806	rs17314064	T	G	rs17314064	23149450	0.0000536	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
X	8599803	rs16985077	G	C	rs16985077	19165232	4.17E-05	NA	NA	NA	200 Japanese ancestry cases; 200 Japanese ancestry controls	Japanese(400)	ALL(400)	ASN(400)	ALL(400)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Research Support, Non-U.S. Gov't	G	KAL1
X	14347127	rs756909	A	T	rs756909	23149450	0.0000516	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
X	97107750	rs318156	A	T	rs318156	23149450	0.0000164	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	T
X	100342265	rs2014595	G	A	rs2014595	23149450	0.00000595	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
X	127452799	rs240199	G	T	rs240199	23149450	0.000033	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A
X	127940011	rs762874	A	C	rs762874	23149450	0.0000477	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	G
X	127941251	rs916208	C	T	rs916208	23149450	0.0000464	NA	NA	NA	718 Japanese ancestry cases; 1,717 Japanese ancestry controls	Japanese(2435)	ALL(2435)	ASN(2435)	ALL(2435)	Panic disorder	HPOID:0100851	Abnormal emotion/affect behavior	DOID:594	panic disorder	D016584	Panic Disorder	EFOID:0004262	panic disorder	Panic disorder	NA	Meta-Analysis	Research Support, Non-U.S. Gov't	A

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:37)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0030319	adinazolam	C039668	37115-32-5	panic disorder	MESH:D016584	therapeutic	2651489
C0030319	alprazolam	D000525	28981-97-7	panic disorder	MESH:D016584	marker/mechanism	11841142
C0030319	alprazolam	D000525	28981-97-7	panic disorder	MESH:D016584	therapeutic	11207340
C0030319	amitriptyline	D000639	50-48-6	panic disorder	MESH:D016584	marker/mechanism	7446764
C0030319	aripiprazole	D000068180	-	panic disorder	MESH:D016584	marker/mechanism	18794657
C0030319	caffeine	D002110	1958/8/2	panic disorder	MESH:D016584	marker/mechanism	17407170
C0030319	cimetidine	D002927	51481-61-9	panic disorder	MESH:D016584	marker/mechanism	509014
C0030319	citalopram	D015283	59729-33-8	panic disorder	MESH:D016584	marker/mechanism	12356120
C0030319	citalopram	D015283	59729-33-8	panic disorder	MESH:D016584	therapeutic	15812270
C0030319	clozapine	D003024	5786-21-0	panic disorder	MESH:D016584	marker/mechanism	11097983
C0030319	clozapine	D003024	5786-21-0	panic disorder	MESH:D016584	therapeutic	11230003
C0030319	doxapram	D004315	309-29-5	panic disorder	MESH:D016584	marker/mechanism	15741000
C0030319	fenfluramine	D005277	458-24-2	panic disorder	MESH:D016584	marker/mechanism	9361714
C0030319	fluoxetine	D005473	54910-89-3	panic disorder	MESH:D016584	marker/mechanism	2521065
C0030319	fluoxetine	D005473	54910-89-3	panic disorder	MESH:D016584	therapeutic	2107764
C0030319	fluvoxamine	D016666	54739-18-3	panic disorder	MESH:D016584	therapeutic	8256637
C0030319	imipramine	D007099	50-49-7	panic disorder	MESH:D016584	therapeutic	2107764
C0030319	lorazepam	D008140	846-49-1	panic disorder	MESH:D016584	therapeutic	2187213
C0030319	mefloquine	D015767	53230-10-7	panic disorder	MESH:D016584	marker/mechanism	1807186
C0030319	methadone	D008691	76-99-3	panic disorder	MESH:D016584	marker/mechanism	1314016
C0030319	nicotine	D009538	-	panic disorder	MESH:D016584	marker/mechanism	3777262
C0030319	levonorgestrel	D016912	797-63-7	panic disorder	MESH:D016584	marker/mechanism	7989280
C0030319	nortriptyline	D009661	72-69-5	panic disorder	MESH:D016584	therapeutic	14642980
C0030319	olanzapine	C076029	132539-06-1	panic disorder	MESH:D016584	therapeutic	15470803
C0030319	peginterferon alfa-2a	C100416	-	panic disorder	MESH:D016584	marker/mechanism	17845538
C0030319	peginterferon alfa-2b	C417083	-	panic disorder	MESH:D016584	marker/mechanism	17845538
C0030319	pentagastrin	D010418	5534-95-2	panic disorder	MESH:D016584	marker/mechanism	11578682
C0030319	phentermine	D010645	122-09-8	panic disorder	MESH:D016584	marker/mechanism	9829290
C0030319	progesterone	D011374	57-83-0	panic disorder	MESH:D016584	marker/mechanism	15996752
C0030319	propranolol	D011433	525-66-6	panic disorder	MESH:D016584	marker/mechanism	3379142
C0030319	propranolol	D011433	525-66-6	panic disorder	MESH:D016584	therapeutic	6871816
C0030319	reserpine	D012110	50-55-5	panic disorder	MESH:D016584	marker/mechanism	8784656
C0030319	ribavirin	D012254	36791-04-5	panic disorder	MESH:D016584	marker/mechanism	17845538
C0030319	sulpiride	D013469	15676-16-1	panic disorder	MESH:D016584	therapeutic	1315108
C0030319	tetrabenazine	D013747	58-46-8	panic disorder	MESH:D016584	marker/mechanism	12355681
C0030319	topiramate	C052342	97240-79-4	panic disorder	MESH:D016584	marker/mechanism	16566634
C0030319	valproic acid	D014635	99-66-1	panic disorder	MESH:D016584	therapeutic	1821239

FDA approved drug and dosage information(Total Drugs:30)
DiseaseID	Drug_name	active_ingredients	strength	Dosage Form/Route	Marketing Status	TE code	RLD	RS
MESH:D016584	abilify	aripiprazole	10MG	TABLET;ORAL	Prescription	AB	Yes	Yes
MESH:D016584	abilify	aripiprazole	1MG/ML Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons	SOLUTION;ORAL	Discontinued	None	Yes	No
MESH:D016584	abilify	aripiprazole	10MG Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons	TABLET, ORALLY DISINTEGRATING;ORAL	Discontinued	None	No	No
MESH:D016584	abilify	aripiprazole	9.75MG/1.3ML (7.5MG/ML)	INJECTABLE;INTRAMUSCULAR	Discontinued	None	No	No
MESH:D016584	abilify	aripiprazole	10MG	TABLET;ORAL	Prescription	AB	Yes	Yes
MESH:D016584	abilify	aripiprazole	1MG/ML Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons	SOLUTION;ORAL	Discontinued	None	Yes	No
MESH:D016584	abilify	aripiprazole	10MG Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons	TABLET, ORALLY DISINTEGRATING;ORAL	Discontinued	None	No	No
MESH:D016584	abilify	aripiprazole	9.75MG/1.3ML (7.5MG/ML)	INJECTABLE;INTRAMUSCULAR	Discontinued	None	No	No
MESH:D016584	abilify	aripiprazole	10MG	TABLET;ORAL	Prescription	AB	Yes	Yes
MESH:D016584	abilify	aripiprazole	1MG/ML Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons	SOLUTION;ORAL	Discontinued	None	Yes	No
MESH:D016584	abilify	aripiprazole	10MG Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons	TABLET, ORALLY DISINTEGRATING;ORAL	Discontinued	None	No	No
MESH:D016584	abilify	aripiprazole	9.75MG/1.3ML (7.5MG/ML)	INJECTABLE;INTRAMUSCULAR	Discontinued	None	No	No
MESH:D016584	abilify	aripiprazole	10MG	TABLET;ORAL	Prescription	AB	Yes	Yes
MESH:D016584	abilify	aripiprazole	1MG/ML Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons	SOLUTION;ORAL	Discontinued	None	Yes	No
MESH:D016584	abilify	aripiprazole	10MG Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons	TABLET, ORALLY DISINTEGRATING;ORAL	Discontinued	None	No	No
MESH:D016584	abilify	aripiprazole	9.75MG/1.3ML (7.5MG/ML)	INJECTABLE;INTRAMUSCULAR	Discontinued	None	No	No
MESH:D016584	zyprexa	olanzapine	2.5MG	TABLET;ORAL	Prescription	AB	Yes	No
MESH:D016584	zyprexa	olanzapine	10MG/VIAL	INJECTABLE;INTRAMUSCULAR	Prescription	AP	Yes	Yes
MESH:D016584	zyprexa	olanzapine	2.5MG	TABLET;ORAL	Prescription	AB	Yes	No
MESH:D016584	zyprexa	olanzapine	10MG/VIAL	INJECTABLE;INTRAMUSCULAR	Prescription	AP	Yes	Yes
MESH:D016584	mirena	levonorgestrel	52MG	INTRAUTERINE DEVICE;INTRAUTERINE	Prescription	None	Yes	Yes
MESH:D016584	levonorgestrel	levonorgestrel	75MG/IMPLANT	IMPLANT;IMPLANTATION	Discontinued	None	No	No
MESH:D016584	topamax	topiramate	100MG	TABLET;ORAL	Prescription	AB	Yes	Yes
MESH:D016584	topamax	topiramate	15MG	CAPSULE;ORAL	Prescription	AB	Yes	No
MESH:D016584	topamax	topiramate	100MG	TABLET;ORAL	Prescription	AB	Yes	Yes
MESH:D016584	topamax	topiramate	15MG	CAPSULE;ORAL	Prescription	AB	Yes	No
MESH:D016584	topamax	topiramate	100MG	TABLET;ORAL	Prescription	AB	Yes	Yes
MESH:D016584	topamax	topiramate	15MG	CAPSULE;ORAL	Prescription	AB	Yes	No
MESH:D016584	topamax	topiramate	100MG	TABLET;ORAL	Prescription	AB	Yes	Yes
MESH:D016584	topamax	topiramate	15MG	CAPSULE;ORAL	Prescription	AB	Yes	No

FDA labeling changes(Total Drugs:30)
DiseaseID	Pediatric_Labeling_Date	Trade_Name	Generic_Name_or_Proper_Name	Indications Studied	Label Changes Summary	Product Labeling	BPCA(B)	PREA(P)	BPCA(B) and PREA(P)	Pediatric Rule (R)	Sponsor	Pediatric Exclusivity Granted Date	NNPS
MESH:D016584	10/29/2007	abilify	aripiprazole	Schizophrenia	Extended schizophrenia indication from adults to adolescents 1317 years Safety and effectiveness in pediatric patients with bipolar mania or agitation associated with schizophrenia or bipolar mania have not been established Efficacy for the maintenance treatment of schizophrenia in the pediatric population has not been evaluated In 6-week placebo controlled efficacy trial in patients 13 17 years with Schizophrenia 30 mg/day was not shown to be more efficacious than 10 mg/day Common adverse events observed were extrapyramidal disorder, somnolence, and tremor; these 3 AEs appear to have a possible dose response relationship Information on dose, AEs, clinical studies	Labeling	B	-	-	-	Otsuka	11/14/2007	FALSE'
MESH:D016584	10/29/2007	abilify	aripiprazole	Schizophrenia	Extended schizophrenia indication from adults to adolescents 1317 years Safety and effectiveness in pediatric patients with bipolar mania or agitation associated with schizophrenia or bipolar mania have not been established Efficacy for the maintenance treatment of schizophrenia in the pediatric population has not been evaluated In 6-week placebo controlled efficacy trial in patients 13 17 years with Schizophrenia 30 mg/day was not shown to be more efficacious than 10 mg/day Common adverse events observed were extrapyramidal disorder, somnolence, and tremor; these 3 AEs appear to have a possible dose response relationship Information on dose, AEs, clinical studies	Labeling	B	-	-	-	Otsuka	11/14/2007	FALSE'
MESH:D016584	10/29/2007	abilify	aripiprazole	Schizophrenia	Extended schizophrenia indication from adults to adolescents 1317 years Safety and effectiveness in pediatric patients with bipolar mania or agitation associated with schizophrenia or bipolar mania have not been established Efficacy for the maintenance treatment of schizophrenia in the pediatric population has not been evaluated In 6-week placebo controlled efficacy trial in patients 13 17 years with Schizophrenia 30 mg/day was not shown to be more efficacious than 10 mg/day Common adverse events observed were extrapyramidal disorder, somnolence, and tremor; these 3 AEs appear to have a possible dose response relationship Information on dose, AEs, clinical studies	Labeling	B	-	-	-	Otsuka	11/14/2007	FALSE'
MESH:D016584	10/29/2007	abilify	aripiprazole	Schizophrenia	Extended schizophrenia indication from adults to adolescents 1317 years Safety and effectiveness in pediatric patients with bipolar mania or agitation associated with schizophrenia or bipolar mania have not been established Efficacy for the maintenance treatment of schizophrenia in the pediatric population has not been evaluated In 6-week placebo controlled efficacy trial in patients 13 17 years with Schizophrenia 30 mg/day was not shown to be more efficacious than 10 mg/day Common adverse events observed were extrapyramidal disorder, somnolence, and tremor; these 3 AEs appear to have a possible dose response relationship Information on dose, AEs, clinical studies	Labeling	B	-	-	-	Otsuka	11/14/2007	FALSE'
MESH:D016584	02/27/2008	abilify	aripiprazole	Bipolar I Disorder	Extended treatment of acute Bipolar Disorder indication from adults to pediatrics 1017 years The efficacy for the maintenance treatment of Bipolar Disorder in the pediatric population has not been evaluated The recommended target dose in Bipolar Disorder is 10 mg/day. In the study of pediatric patients 10 17 years with Bipolar Mania, 4 common adverse reactions had a possible dose response relationship at 4 weeks; extrapyramidal disorder, somnolence, akathisia and salivary hypersecretion Information on dose, AEs, clinical studies	Labeling	-	-	B, P	-	Otsuka	11/14/2007	FALSE'
MESH:D016584	02/27/2008	abilify	aripiprazole	Bipolar I Disorder	Extended treatment of acute Bipolar Disorder indication from adults to pediatrics 1017 years The efficacy for the maintenance treatment of Bipolar Disorder in the pediatric population has not been evaluated The recommended target dose in Bipolar Disorder is 10 mg/day. In the study of pediatric patients 10 17 years with Bipolar Mania, 4 common adverse reactions had a possible dose response relationship at 4 weeks; extrapyramidal disorder, somnolence, akathisia and salivary hypersecretion Information on dose, AEs, clinical studies	Labeling	-	-	B, P	-	Otsuka	11/14/2007	FALSE'
MESH:D016584	02/27/2008	abilify	aripiprazole	Bipolar I Disorder	Extended treatment of acute Bipolar Disorder indication from adults to pediatrics 1017 years The efficacy for the maintenance treatment of Bipolar Disorder in the pediatric population has not been evaluated The recommended target dose in Bipolar Disorder is 10 mg/day. In the study of pediatric patients 10 17 years with Bipolar Mania, 4 common adverse reactions had a possible dose response relationship at 4 weeks; extrapyramidal disorder, somnolence, akathisia and salivary hypersecretion Information on dose, AEs, clinical studies	Labeling	-	-	B, P	-	Otsuka	11/14/2007	FALSE'
MESH:D016584	02/27/2008	abilify	aripiprazole	Bipolar I Disorder	Extended treatment of acute Bipolar Disorder indication from adults to pediatrics 1017 years The efficacy for the maintenance treatment of Bipolar Disorder in the pediatric population has not been evaluated The recommended target dose in Bipolar Disorder is 10 mg/day. In the study of pediatric patients 10 17 years with Bipolar Mania, 4 common adverse reactions had a possible dose response relationship at 4 weeks; extrapyramidal disorder, somnolence, akathisia and salivary hypersecretion Information on dose, AEs, clinical studies	Labeling	-	-	B, P	-	Otsuka	11/14/2007	FALSE'
MESH:D016584	11/19/2009	abilify	aripiprazole	Irritability associated with autistic disorder	Safety and effectiveness in pediatric patients demonstrating irritability associated with autistic disorder were established in two placebo-controlled clinical trials in pediatric patients 6 - 17 years of age Most common adverse reactions observed in pediatric clinical trials in patients with autistic disorder included sedation, fatigue, vomiting, somnolence, tremor, pyrexia, drooling, decreased appetite, salivary hypersecretion, extrapyramidal disorder, and lethargy. Fatigue was a possible dose-response adverse reaction. Information on dosing, adverse reactions, and clinical studies	Labeling	-	P	-	-	Otsuka	-	FALSE'
MESH:D016584	11/19/2009	abilify	aripiprazole	Irritability associated with autistic disorder	Safety and effectiveness in pediatric patients demonstrating irritability associated with autistic disorder were established in two placebo-controlled clinical trials in pediatric patients 6 - 17 years of age Most common adverse reactions observed in pediatric clinical trials in patients with autistic disorder included sedation, fatigue, vomiting, somnolence, tremor, pyrexia, drooling, decreased appetite, salivary hypersecretion, extrapyramidal disorder, and lethargy. Fatigue was a possible dose-response adverse reaction. Information on dosing, adverse reactions, and clinical studies	Labeling	-	P	-	-	Otsuka	-	FALSE'
MESH:D016584	11/19/2009	abilify	aripiprazole	Irritability associated with autistic disorder	Safety and effectiveness in pediatric patients demonstrating irritability associated with autistic disorder were established in two placebo-controlled clinical trials in pediatric patients 6 - 17 years of age Most common adverse reactions observed in pediatric clinical trials in patients with autistic disorder included sedation, fatigue, vomiting, somnolence, tremor, pyrexia, drooling, decreased appetite, salivary hypersecretion, extrapyramidal disorder, and lethargy. Fatigue was a possible dose-response adverse reaction. Information on dosing, adverse reactions, and clinical studies	Labeling	-	P	-	-	Otsuka	-	FALSE'
MESH:D016584	11/19/2009	abilify	aripiprazole	Irritability associated with autistic disorder	Safety and effectiveness in pediatric patients demonstrating irritability associated with autistic disorder were established in two placebo-controlled clinical trials in pediatric patients 6 - 17 years of age Most common adverse reactions observed in pediatric clinical trials in patients with autistic disorder included sedation, fatigue, vomiting, somnolence, tremor, pyrexia, drooling, decreased appetite, salivary hypersecretion, extrapyramidal disorder, and lethargy. Fatigue was a possible dose-response adverse reaction. Information on dosing, adverse reactions, and clinical studies	Labeling	-	P	-	-	Otsuka	-	FALSE'
MESH:D016584	9/6/2014	abilify	aripiprazole	Maintenance treatment of irritability associated with autistic disorder	Efficacy for the maintenance treatment of irritability associated with autistic disorder was not established in a 12 week clinical trial in 85 pediatric patients 6-17 years Information on clinical trialPostmarketing study	Labeling	-	P	-	-	Otsuka	-	FALSE'
MESH:D016584	9/6/2014	abilify	aripiprazole	Maintenance treatment of irritability associated with autistic disorder	Efficacy for the maintenance treatment of irritability associated with autistic disorder was not established in a 12 week clinical trial in 85 pediatric patients 6-17 years Information on clinical trialPostmarketing study	Labeling	-	P	-	-	Otsuka	-	FALSE'
MESH:D016584	9/6/2014	abilify	aripiprazole	Maintenance treatment of irritability associated with autistic disorder	Efficacy for the maintenance treatment of irritability associated with autistic disorder was not established in a 12 week clinical trial in 85 pediatric patients 6-17 years Information on clinical trialPostmarketing study	Labeling	-	P	-	-	Otsuka	-	FALSE'
MESH:D016584	9/6/2014	abilify	aripiprazole	Maintenance treatment of irritability associated with autistic disorder	Efficacy for the maintenance treatment of irritability associated with autistic disorder was not established in a 12 week clinical trial in 85 pediatric patients 6-17 years Information on clinical trialPostmarketing study	Labeling	-	P	-	-	Otsuka	-	FALSE'
MESH:D016584	08/14/2008	zyprexa	olanzapine	schizophrenia; bipolar disorder	Safety and effectiveness have not been established for patients less than 18 years of age In an analysis of placebo-controlled olanzapine monotherapy studies of adolescent patients, including those with schizophrenia or bipolar disorder, olanzapine was associated with: oHyperglycemia - a statistically significantly greater mean change in fasting glucose levels compared to placebo oHyperlipidemia statistically significant increases compared to placebo in fasting triglycerides, fasting total cholesterol and fasting LDL cholesterol oWeight gain olanzapine treated patients gained an average of 4.6 kg, compared to an average of 0.3 kg in placebo-treated patients with a median exposure of 3 weeks; Average weight gain during long-term therapy was 7.4 kg	-	B	-	-	-	Lilly	10/1/2007	FALSE'
MESH:D016584	08/14/2008	zyprexa	olanzapine	schizophrenia; bipolar disorder	Safety and effectiveness have not been established for patients less than 18 years of age In an analysis of placebo-controlled olanzapine monotherapy studies of adolescent patients, including those with schizophrenia or bipolar disorder, olanzapine was associated with: oHyperglycemia - a statistically significantly greater mean change in fasting glucose levels compared to placebo oHyperlipidemia statistically significant increases compared to placebo in fasting triglycerides, fasting total cholesterol and fasting LDL cholesterol oWeight gain olanzapine treated patients gained an average of 4.6 kg, compared to an average of 0.3 kg in placebo-treated patients with a median exposure of 3 weeks; Average weight gain during long-term therapy was 7.4 kg	-	B	-	-	-	Lilly	10/1/2007	FALSE'
MESH:D016584	4/12/2009	zyprexa	olanzapine	Treatment of manic or mixed episodes of bipolar I disorder and schizophrenia in adolescents ages 13-17	Extended schizophrenia and manic or mixed episodes of bipolar I disorder indications from adults to adolescents 1317 years of age Safety and effectiveness in children < 13 years of age have not been established Recommended starting dose for adolescents is lower than that for adults Compared to patients from adult clinical trials, adolescents were likely to gain more weight, experience increased sedation, and have greater increases in total cholesterol, triglycerides, LDL cholesterol, prolactin and hepatic transaminase levels Information on dosing, adverse reactions, pharmacokinetics, clinical studies	Labeling	B	-	-	-	Lilly	10/1/2007	TRUE'
MESH:D016584	4/12/2009	zyprexa	olanzapine	Treatment of manic or mixed episodes of bipolar I disorder and schizophrenia in adolescents ages 13-17	Extended schizophrenia and manic or mixed episodes of bipolar I disorder indications from adults to adolescents 1317 years of age Safety and effectiveness in children < 13 years of age have not been established Recommended starting dose for adolescents is lower than that for adults Compared to patients from adult clinical trials, adolescents were likely to gain more weight, experience increased sedation, and have greater increases in total cholesterol, triglycerides, LDL cholesterol, prolactin and hepatic transaminase levels Information on dosing, adverse reactions, pharmacokinetics, clinical studies	Labeling	B	-	-	-	Lilly	10/1/2007	TRUE'
MESH:D016584	1/10/2009	mirena	levonorgestrel-releasing intrauterine system	Treatment of heavy menstrual bleeding for women using intrauterine contraception	New indication for the treatment of heavy menstrual bleeding for women who choose to use intrauterine contraception Use before menarche is not indicated	Labeling	-	P	-	-	Berlex	-	TRUE'
MESH:D016584	10/7/2009	plan b one step	levonorgestrel	Emergency contraception - OTC in women 17 years and older; RX for women younger than age 17 years	New single dose 1.5 mg tablet New dosage regimen	Labeling	-	P	-	-	Duramed	-	FALSE'
MESH:D016584	12/22/2009	topamax	topiramate	Migraine Prophylaxis	Safety and effectiveness for migraine prevention in pediatric patients have not been established Dose-related increased shift in serum creatinine in adolescent patients occurred in a clinical study Information added to Warnings and Precautions and Pediatric Use	Labeling	-	P	-	-	Ortho-McNeil-Janssen	-	FALSE'
MESH:D016584	12/22/2009	topamax	topiramate	Migraine Prophylaxis	Safety and effectiveness for migraine prevention in pediatric patients have not been established Dose-related increased shift in serum creatinine in adolescent patients occurred in a clinical study Information added to Warnings and Precautions and Pediatric Use	Labeling	-	P	-	-	Ortho-McNeil-Janssen	-	FALSE'
MESH:D016584	12/22/2009	topamax	topiramate	Adjunctive Treatment for Partial Onset Epilepsy in Infants and Toddlers 1 to 24 months	Effectiveness was not demonstrated as adjunctive therapy in a randomized, double-blind trial in infants/toddlers 1 to 24 months of age with refractory partial onset seizures Trials in infants/toddlers 1 to 24 months suggested some adverse reactions/toxicities not previously observed in older pediatric patients and adults; i.e, growth/length retardation, certain clinical laboratory abnormalities, and other adverse reactions/toxicities that occurred with a greater frequency and/or greater severity than had been recognized previously from studies in older pediatric patients or adults for various indications. Information added to Warnings and Precautions and Pediatric Use	Labeling	B	-	-	-	Ortho-McNeil-Janssen	07/24/2008	FALSE'
MESH:D016584	12/22/2009	topamax	topiramate	Adjunctive Treatment for Partial Onset Epilepsy in Infants and Toddlers 1 to 24 months	Effectiveness was not demonstrated as adjunctive therapy in a randomized, double-blind trial in infants/toddlers 1 to 24 months of age with refractory partial onset seizures Trials in infants/toddlers 1 to 24 months suggested some adverse reactions/toxicities not previously observed in older pediatric patients and adults; i.e, growth/length retardation, certain clinical laboratory abnormalities, and other adverse reactions/toxicities that occurred with a greater frequency and/or greater severity than had been recognized previously from studies in older pediatric patients or adults for various indications. Information added to Warnings and Precautions and Pediatric Use	Labeling	B	-	-	-	Ortho-McNeil-Janssen	07/24/2008	FALSE'
MESH:D016584	07/15/2011	topamax	topiramate	Monotherapy for partial onset or primary generalized tonic-clonic seizures	Expanded age range down to 2 years; previously approved for monotherapy for partial onset or primary generalized tonic-clonic seizures in patients10 years and older Information on weight based dosing in 2 to < 10 yearsPostmarketing study	Labeling	-	P	-	-	Janssen	-	FALSE'
MESH:D016584	07/15/2011	topamax	topiramate	Monotherapy for partial onset or primary generalized tonic-clonic seizures	Expanded age range down to 2 years; previously approved for monotherapy for partial onset or primary generalized tonic-clonic seizures in patients10 years and older Information on weight based dosing in 2 to < 10 yearsPostmarketing study	Labeling	-	P	-	-	Janssen	-	FALSE'
MESH:D016584	03/28/2014	topamax	topiramate	Prophylaxis of migraine headache	Approved for use in pediatric patients 12 years and older Safety and effectiveness in pediatric patients less than12 years have not been established for the prophylaxis treatment of migraine headache In the adolescent migraine trials (12 to 17 years), the most commonly observed adverse reactions were: paresthesia, upper respiratory tract infection, anorexia, and abdominal pain The most common cognitive adverse reaction in pooled double-blind studies in adolescent patients 12 to 17 years was difficulty with concentration/attention Markedly abnormally low serum bicarbonate values indicative of metabolic acidosis were reported in topiramate-treated adolescent migraine patients In topiramate-treated patients 12 to 17 years compared to placebo-treated patients, abnormally increased results were more frequent for creatinine, BUN, uric acid, chloride, ammonia, total protein, and platelets. Abnormally decreased results were observed with topiramate vs placebo treatment for phosphorus and bicarbonate Notable changes (increases and decreases) from baseline in systolic blood pressure, diastolic blood pressure, and pulse were observed more commonly in adolescents treated with topiramate compared to adolescents treated with placebo Information on dosing, adverse reactions, laboratory abnormalities, and clinical trials Postmarketing study	Labeling	-	P	-	-	Janssen	-	FALSE'
MESH:D016584	03/28/2014	topamax	topiramate	Prophylaxis of migraine headache	Approved for use in pediatric patients 12 years and older Safety and effectiveness in pediatric patients less than12 years have not been established for the prophylaxis treatment of migraine headache In the adolescent migraine trials (12 to 17 years), the most commonly observed adverse reactions were: paresthesia, upper respiratory tract infection, anorexia, and abdominal pain The most common cognitive adverse reaction in pooled double-blind studies in adolescent patients 12 to 17 years was difficulty with concentration/attention Markedly abnormally low serum bicarbonate values indicative of metabolic acidosis were reported in topiramate-treated adolescent migraine patients In topiramate-treated patients 12 to 17 years compared to placebo-treated patients, abnormally increased results were more frequent for creatinine, BUN, uric acid, chloride, ammonia, total protein, and platelets. Abnormally decreased results were observed with topiramate vs placebo treatment for phosphorus and bicarbonate Notable changes (increases and decreases) from baseline in systolic blood pressure, diastolic blood pressure, and pulse were observed more commonly in adolescents treated with topiramate compared to adolescents treated with placebo Information on dosing, adverse reactions, laboratory abnormalities, and clinical trials Postmarketing study	Labeling	-	P	-	-	Janssen	-	FALSE'