PedAM

Pediatric Disease Annotations & Medicines


	pancreatic ductal carcinoma

Disease ID	1586
Disease	pancreatic ductal carcinoma
Definition	Carcinoma that arises from the PANCREATIC DUCTS. It accounts for the majority of cancers derived from the PANCREAS.
Synonym	carcinoma, ductal, pancreatic carcinoma, pancreas duct-cell carcinoma, pancreatic ductal carcinoma, pancreatic ductal [disease/finding] carcinomas, pancreas duct-cell carcinomas, pancreatic ductal duct cell carcinoma of the pancreas duct cell carcinoma, pancreas duct-cell carcinoma of the pancreas duct-cell carcinoma, pancreas duct-cell carcinomas, pancreas ductal carcinoma of the pancreas ductal carcinoma, pancreatic ductal carcinomas, pancreatic pancreas duct-cell carcinoma pancreas duct-cell carcinomas pancreatic duct cell carcinoma pancreatic ductal carcinomas
DOID	DOID:3587
UMLS	C0887833
MeSH	D021441
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:3) C0153676 \| pulmonary metastasis \| 1 C0494165 \| liver metastases \| 1 C0030305 \| pancreatitis \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:20) NOTCH3 \| 4854 \| CTD_human NOTCH1 \| 4851 \| CTD_human VEGFA \| 7422 \| CTD_human NDRG1 \| 10397 \| CTD_human NFE2L2 \| 4780 \| CTD_human CDKN2A \| 1029 \| CTD_human KRAS \| 3845 \| CTD_human HSPA1A \| 3303 \| CTD_human JAG1 \| 182 \| CTD_human HSPA1B \| 3304 \| CTD_human HEY1 \| 23462 \| CTD_human ARG2 \| 384 \| CTD_human AGTR1 \| 185 \| CTD_human DTX1 \| 1840 \| CTD_human HEY2 \| 23493 \| CTD_human NOTCH4 \| 4855 \| CTD_human JAG2 \| 3714 \| CTD_human MSLN \| 10232 \| CTD_human HES1 \| 3280 \| CTD_human DTX4 \| 23220 \| CTD_human
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:1) 3845 \| KRAS \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:98) 1087 \| CEACAM7 \| DISEASES 54474 \| KRT20 \| DISEASES 51208 \| CLDN18 \| DISEASES 1113 \| CHGA \| DISEASES 1048 \| CEACAM5 \| DISEASES 4055 \| LTBR \| DISEASES 2745 \| GLRX \| DISEASES 50674 \| NEUROG3 \| DISEASES 5266 \| PI3 \| DISEASES 1088 \| CEACAM8 \| DISEASES 5880 \| RAC2 \| DISEASES 8854 \| ALDH1A2 \| DISEASES 29775 \| CARD10 \| DISEASES 1890 \| TYMP \| DISEASES 81 \| ACTN4 \| DISEASES 144132 \| DNHD1 \| DISEASES 3845 \| KRAS \| DISEASES 27429 \| HTRA2 \| DISEASES 3417 \| IDH1 \| DISEASES 384 \| ARG2 \| DISEASES 4481 \| MSR1 \| DISEASES 1387 \| CREBBP \| DISEASES 10552 \| ARPC1A \| DISEASES 6774 \| STAT3 \| DISEASES 7157 \| TP53 \| DISEASES 8915 \| BCL10 \| DISEASES 55294 \| FBXW7 \| DISEASES 1562 \| CYP2C18 \| DISEASES 11197 \| WIF1 \| DISEASES 3099 \| HK2 \| DISEASES 84315 \| MON1A \| DISEASES 5267 \| SERPINA4 \| DISEASES 6240 \| RRM1 \| DISEASES 390061 \| OR51Q1 \| DISEASES 51029 \| DESI2 \| DISEASES 9079 \| LDB2 \| DISEASES 3872 \| KRT17 \| DISEASES 9134 \| CCNE2 \| DISEASES 3265 \| HRAS \| DISEASES 947 \| CD34 \| DISEASES 8793 \| TNFRSF10D \| DISEASES 56667 \| MUC13 \| DISEASES 3642 \| INSM1 \| DISEASES 9840 \| TESPA1 \| DISEASES 63967 \| CLSPN \| DISEASES 653499 \| LGALS7B \| DISEASES 84792 \| FAM220A \| DISEASES 5315 \| PKM \| DISEASES 8289 \| ARID1A \| DISEASES 3855 \| KRT7 \| DISEASES 942 \| CD86 \| DISEASES 9075 \| CLDN2 \| DISEASES 3091 \| HIF1A \| DISEASES 6799 \| SULT1A2 \| DISEASES 4602 \| MYB \| DISEASES 5764 \| PTN \| DISEASES 4089 \| SMAD4 \| DISEASES 1364 \| CLDN4 \| DISEASES 1869 \| E2F1 \| DISEASES 8650 \| NUMB \| DISEASES 5789 \| PTPRD \| DISEASES 23560 \| GTPBP4 \| DISEASES 7052 \| TGM2 \| DISEASES 2058 \| EPRS \| DISEASES 6648 \| SOD2 \| DISEASES 4194 \| MDM4 \| DISEASES 3068 \| HDGF \| DISEASES 4582 \| MUC1 \| DISEASES 448834 \| KPRP \| DISEASES 1791 \| DNTT \| DISEASES 2030 \| SLC29A1 \| DISEASES 7422 \| VEGFA \| DISEASES 4855 \| NOTCH4 \| DISEASES 4920 \| ROR2 \| DISEASES 50943 \| FOXP3 \| DISEASES 5935 \| RBM3 \| DISEASES 369 \| ARAF \| DISEASES 64344 \| HIF3A \| DISEASES 219 \| ALDH1B1 \| DISEASES 768 \| CA9 \| DISEASES 3963 \| LGALS7 \| DISEASES 2592 \| GALT \| DISEASES 375790 \| AGRN \| DISEASES 3704 \| ITPA \| DISEASES 1045 \| CDX2 \| DISEASES 10232 \| MSLN \| DISEASES 2054 \| STX2 \| DISEASES 10112 \| KIF20A \| DISEASES 8861 \| LDB1 \| DISEASES 1029 \| CDKN2A \| DISEASES 7701 \| ZNF142 \| DISEASES 4588 \| MUC6 \| DISEASES 196527 \| ANO6 \| DISEASES 4583 \| MUC2 \| DISEASES 4585 \| MUC4 \| DISEASES 4586 \| MUC5AC \| DISEASES 5297 \| PI4KA \| DISEASES 7409 \| VAV1 \| DISEASES
Locus	(Waiting for update.)

Disease ID	1586
Disease	pancreatic ductal carcinoma
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:3) HP:0030731 \| Carcinoma \| 1 HP:0002664 \| Neoplasia \| 1 HP:0001733 \| Pancreatic inflammation \| 1

Disease ID	1586
Disease	pancreatic ductal carcinoma
Manually Symptom	(Waiting for update.)
Text Mined Symptom	(Waiting for update.)

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:2)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0887833	cisplatin	D002945	15663-27-1	carcinoma, pancreatic ductal	MESH:D021441	therapeutic	21613822
C0887833	gemcitabine	C056507	103882-84-4	carcinoma, pancreatic ductal	MESH:D021441	therapeutic	21613822

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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