PedAM

Pediatric Disease Annotations & Medicines


	otitis externa

Disease ID	1547
Disease	otitis externa
Definition	A disorder characterized by an infectious process involving the outer ear and ear canal. Contributory factors include excessive water exposure (swimmer's ear infection) and cuts in the ear canal. Symptoms include fullness, itching, swelling and marked discomfort in the ear and ear drainage.
Synonym	ear swimmer's ear swimmers ears swimmers external ear infection infec otitis externa nos infectious otitis externa infective oe infective otitis externa infective otitis externa (disorder) infective otitis externa [dup] (disorder) infective otitis externa nos infective otitis externa nos (disorder) infective otitis externa, nos infective otitis externa, unspecified outer ear infection swimmer ear swimmer's ear swimmers ear unspecified infective otitis externa unspecified infective otitis externa (disorder)
DOID	DOID:9463
UMLS	C0021355
MeSH	D010032
SNOMED-CT	SNOMEDCT_US_2016_09_01:86981007
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:20) C0029443 \| osteomyelitis \| 4 C0029882 \| otitis media \| 3 C0013595 \| eczema \| 2 C0271429 \| acute otitis media \| 2 C0004623 \| bacterial infection \| 2 C0011603 \| dermatitis \| 1 C0007642 \| cellulitis \| 1 C0042769 \| viral infection \| 1 C0026764 \| myeloma \| 1 C0007785 \| cerebral infarct \| 1 C0004623 \| bacterial infections \| 1 C0011615 \| atopic dermatitis \| 1 C0271454 \| chronic suppurative otitis media \| 1 C0003090 \| ankylosis \| 1 C0155540 \| discharging ear \| 1 C0007785 \| cerebral infarction \| 1 C0151311 \| cranial nerve palsy \| 1 C0026764 \| multiple myeloma \| 1 C0024904 \| mastoiditis \| 1 C0015464 \| facial nerve palsy \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:39) 2767 \| GNA11 \| DISEASES 3861 \| KRT14 \| DISEASES 123263 \| MTFMT \| DISEASES 1666 \| DECR1 \| DISEASES 2521 \| FUS \| DISEASES 1401 \| CRP \| DISEASES 23523 \| CABIN1 \| DISEASES 27143 \| PALD1 \| DISEASES 1991 \| ELANE \| DISEASES 8626 \| TP63 \| DISEASES 5423 \| POLB \| DISEASES 805 \| CALM2 \| DISEASES 90525 \| SHF \| DISEASES 808 \| CALM3 \| DISEASES 3856 \| KRT8 \| DISEASES 3868 \| KRT16 \| DISEASES 171558 \| PTCRA \| DISEASES 54498 \| SMOX \| DISEASES 695 \| BTK \| DISEASES 2147 \| F2 \| DISEASES 23212 \| RRS1 \| DISEASES 11247 \| NXPH4 \| DISEASES 9547 \| CXCL14 \| DISEASES 11315 \| PARK7 \| DISEASES 25870 \| SUMF2 \| DISEASES 124454 \| EARS2 \| DISEASES 875 \| CBS \| DISEASES 57591 \| MKL1 \| DISEASES 801 \| CALM1 \| DISEASES 56980 \| PRDM10 \| DISEASES 3880 \| KRT19 \| DISEASES 2058 \| EPRS \| DISEASES 2316 \| FLNA \| DISEASES 1676 \| DFFA \| DISEASES 4267 \| CD99 \| DISEASES 6490 \| PMEL \| DISEASES 81704 \| DOCK8 \| DISEASES 83695 \| RHNO1 \| DISEASES 6223 \| RPS19 \| DISEASES
Locus	(Waiting for update.)

Disease ID	1547
Disease	otitis externa
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:14) HP:0002754 \| Bone infection \| 4 HP:0000388 \| Otitis media \| 3 HP:0000964 \| Eczema \| 2 HP:0012531 \| Pain \| 2 HP:0000371 \| Acute middle ear infection \| 2 HP:0011986 \| Ectopic bone formation \| 1 HP:0006775 \| Multiple myeloma \| 1 HP:0010628 \| Facial palsy, unilateral or bilateral \| 1 HP:0001047 \| Atopic dermatitis \| 1 HP:0100658 \| Bacterial infection of skin \| 1 HP:0030766 \| Otalgia \| 1 HP:0002664 \| Neoplasia \| 1 HP:0006824 \| Cranial nerve palsy \| 1 HP:0030731 \| Carcinoma \| 1

Disease ID	1547
Disease	otitis externa
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:1) C0030193 \| pain \| 2

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:2)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0021355	carbenicillin	D002228	4697-36-3	otitis externa	MESH:D010032	therapeutic	6176609
C0021355	minoxidil	D008914	38304-91-5	otitis externa	MESH:D010032	marker/mechanism	3390339

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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