PedAM
Pediatric Disease Annotations & Medicines
| osteochondritis dissecans | ||||
| Disease ID | 1020 |
|---|---|
| Disease | osteochondritis dissecans |
| Integrated Phenotype | HPO | Name(Total Integrated Phenotypes:13) HP:0006376 | Limited elbow flexion HP:0002829 | Arthralgia HP:0001367 | Abnormal joint morphology HP:0009050 | Quadriceps muscle atrophy HP:0001386 | Joint swelling HP:0002815 | Abnormality of the knee HP:0003184 | Decreased hip abduction HP:0001376 | Limitation of joint mobility HP:0001377 | Limited elbow extension HP:0011843 | Abnormality of skeletal physiology HP:0001387 | Joint stiffness HP:0002992 | Abnormality of the tibia HP:0001288 | Gait disturbance |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:3) |
| Disease ID | 1020 |
|---|---|
| Disease | osteochondritis dissecans |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
All Snps(Total Genotypes:48) | |||||||||||||
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| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs1000592 | 23928294 | 200909 | HTR3D | umls:C0029421 | BeFree | The case-control analyses revealed a nominal significant association of the HTR3D variant rs1000592 (p.H52R) with OCD (p=0.029) which was also evident after combination of the case-control and the trio-results (p=0.024). | 0.000271442 | 2013 | NA | 2 | 118939624 | C | A |
| rs1000952 | 23928294 | 200909 | HTR3D | umls:C0029421 | BeFree | The case-control analyses revealed a nominal significant association of the HTR3D variant rs1000592 (p.H52R) with OCD (p=0.029) which was also evident after combination of the case-control and the trio-results (p=0.024). | 0.000271442 | 2013 | HTR3D | 3 | 184038034 | G | T,A |
| rs10070190 | 23337130 | 10215 | OLIG2 | umls:C0029421 | BeFree | Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD. | 0.000542884 | 2012 | NA | 5 | 26866262 | G | A |
| rs10070190 | 23337130 | 121278 | TPH2 | umls:C0029421 | BeFree | Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD. | 0.000814326 | 2012 | NA | 5 | 26866262 | G | A |
| rs10070190 | 23337130 | 1007 | CDH9 | umls:C0029421 | BeFree | Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD. | 0.000271442 | 2012 | NA | 5 | 26866262 | G | A |
| rs10070190 | 23337130 | 2892 | GRIA3 | umls:C0029421 | BeFree | Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD. | 0.000271442 | 2012 | NA | 5 | 26866262 | G | A |
| rs10491734 | 23411042 | 6505 | SLC1A1 | umls:C0029421 | BeFree | This case-control study enrolled 578 obsessive-compulsive disorder (OCD) patients and 649 controls and genotyped rs10491734, rs2228622, rs301430 and rs301443 to replicate association of the SLC1A1 gene with OCD in ethnic Han Chinese. | 0.005428837 | 2012 | NA | 9 | 4482706 | T | C |
| rs1074815 | 23337130 | 121278 | TPH2 | umls:C0029421 | BeFree | Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD. | 0.000814326 | 2012 | NA | NA | NA | NA | NA |
| rs1074815 | 23337130 | 2892 | GRIA3 | umls:C0029421 | BeFree | Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD. | 0.000271442 | 2012 | NA | NA | NA | NA | NA |
| rs1074815 | 23337130 | 1007 | CDH9 | umls:C0029421 | BeFree | Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD. | 0.000271442 | 2012 | NA | NA | NA | NA | NA |
| rs1074815 | 23337130 | 10215 | OLIG2 | umls:C0029421 | BeFree | Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD. | 0.000542884 | 2012 | NA | NA | NA | NA | NA |
| rs11783752 | 23337130 | 121278 | TPH2 | umls:C0029421 | BeFree | Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD. | 0.000814326 | 2012 | NA | 8 | 20192013 | G | A |
| rs11783752 | 23337130 | 10215 | OLIG2 | umls:C0029421 | BeFree | Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD. | 0.000542884 | 2012 | NA | 8 | 20192013 | G | A |
| rs11783752 | 23337130 | 2892 | GRIA3 | umls:C0029421 | BeFree | Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD. | 0.000271442 | 2012 | NA | 8 | 20192013 | G | A |
| rs11783752 | 23337130 | 1007 | CDH9 | umls:C0029421 | BeFree | Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD. | 0.000271442 | 2012 | NA | 8 | 20192013 | G | A |
| rs2228622 | 23411042 | 6505 | SLC1A1 | umls:C0029421 | BeFree | This case-control study enrolled 578 obsessive-compulsive disorder (OCD) patients and 649 controls and genotyped rs10491734, rs2228622, rs301430 and rs301443 to replicate association of the SLC1A1 gene with OCD in ethnic Han Chinese. | 0.005428837 | 2012 | SLC1A1 | 9 | 4564432 | G | A |
| rs25531 | 23630162 | 6532 | SLC6A4 | umls:C0029421 | BeFree | Likewise, the higher expressing LAC haplotype (5-HTTLPR/rs25531/rs25532) was more frequent in TD probands than in controls (P = 0.024; OR, 1.33) and also in the TD alone group versus the TD plus OCD group (P = 0.0013; OR, 2.14). | 0.007600372 | 2013 | SLC6A4;LOC105371720 | 17 | 30237328 | T | C |
| rs25531 | 23630162 | 3938 | LCT | umls:C0029421 | BeFree | Likewise, the higher expressing LAC haplotype (5-HTTLPR/rs25531/rs25532) was more frequent in TD probands than in controls (P = 0.024; OR, 1.33) and also in the TD alone group versus the TD plus OCD group (P = 0.0013; OR, 2.14). | 0.000271442 | 2013 | SLC6A4;LOC105371720 | 17 | 30237328 | T | C |
| rs25531 | 17375136 | 6532 | SLC6A4 | umls:C0029421 | BeFree | To explore the hypothesis that this variability might result from the effects of differing combinations of overlooked variants within SLC6A4 together with small OCD and control sample sizes, we studied three common functional polymorphisms (5-HTTLPR, STin2, and the newly discovered SNP, rs25531) in the largest sample size of OCD patients (N=347) and controls (N=749) ever investigated. | 0.007600372 | 2007 | SLC6A4;LOC105371720 | 17 | 30237328 | T | C |
| rs25532 | 18055562 | 6532 | SLC6A4 | umls:C0029421 | BeFree | Haplotype-based testing of rs25532 and all other known non-coding functional SLC6A4 variants revealed a highly significant omnibus association with OCD in a large case-control sample. | 0.007600372 | 2008 | SLC6A4;LOC105371720 | 17 | 30237152 | G | A |
| rs25532 | 23630162 | 3938 | LCT | umls:C0029421 | BeFree | Likewise, the higher expressing LAC haplotype (5-HTTLPR/rs25531/rs25532) was more frequent in TD probands than in controls (P = 0.024; OR, 1.33) and also in the TD alone group versus the TD plus OCD group (P = 0.0013; OR, 2.14). | 0.000271442 | 2013 | SLC6A4;LOC105371720 | 17 | 30237152 | G | A |
| rs25532 | 23630162 | 6532 | SLC6A4 | umls:C0029421 | BeFree | Likewise, the higher expressing LAC haplotype (5-HTTLPR/rs25531/rs25532) was more frequent in TD probands than in controls (P = 0.024; OR, 1.33) and also in the TD alone group versus the TD plus OCD group (P = 0.0013; OR, 2.14). | 0.007600372 | 2013 | SLC6A4;LOC105371720 | 17 | 30237152 | G | A |
| rs267606625 | NA | 176 | ACAN | umls:C0029421 | CLINVAR | NA | 0.12 | NA | ACAN | 15 | 88872941 | G | A |
| rs2834070 | 23337130 | 2892 | GRIA3 | umls:C0029421 | BeFree | Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD. | 0.000271442 | 2012 | LOC105372784 | 21 | 33015144 | G | T |
| rs2834070 | 23337130 | 121278 | TPH2 | umls:C0029421 | BeFree | Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD. | 0.000814326 | 2012 | LOC105372784 | 21 | 33015144 | G | T |
| rs2834070 | 23337130 | 10215 | OLIG2 | umls:C0029421 | BeFree | Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD. | 0.000542884 | 2012 | LOC105372784 | 21 | 33015144 | G | T |
| rs2834070 | 23337130 | 1007 | CDH9 | umls:C0029421 | BeFree | Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD. | 0.000271442 | 2012 | LOC105372784 | 21 | 33015144 | G | T |
| rs28521337 | 19370765 | 574436 | MIR485 | umls:C0029421 | BeFree | We have found the C allele of rs28521337, located in a functional target site for miR-485-3p in the truncated isoform of NTRK3, to be significantly associated with the hoarding phenotype of OCD. | 0.000271442 | 2009 | NTRK3 | 15 | 87978049 | C | G |
| rs28521337 | 19370765 | 4916 | NTRK3 | umls:C0029421 | BeFree | We have found the C allele of rs28521337, located in a functional target site for miR-485-3p in the truncated isoform of NTRK3, to be significantly associated with the hoarding phenotype of OCD. | 0.000542884 | 2009 | NTRK3 | 15 | 87978049 | C | G |
| rs2857766 | 20452030 | 4340 | MOG | umls:C0029421 | BeFree | Our study provides first evidence that the MOG G511C (Val142Leu) polymorphism might be associated with structural changes in the total white matter volumes of OCD patients, which might indicate an interaction between genetics and neuroimaging abnormalities in these patients. | 0.000542884 | 2010 | MOG | 6 | 29666226 | G | C |
| rs301430 | 23411042 | 6505 | SLC1A1 | umls:C0029421 | BeFree | This case-control study enrolled 578 obsessive-compulsive disorder (OCD) patients and 649 controls and genotyped rs10491734, rs2228622, rs301430 and rs301443 to replicate association of the SLC1A1 gene with OCD in ethnic Han Chinese. | 0.005428837 | 2012 | SLC1A1 | 9 | 4576680 | T | C |
| rs301443 | 23411042 | 6505 | SLC1A1 | umls:C0029421 | BeFree | This case-control study enrolled 578 obsessive-compulsive disorder (OCD) patients and 649 controls and genotyped rs10491734, rs2228622, rs301430 and rs301443 to replicate association of the SLC1A1 gene with OCD in ethnic Han Chinese. | 0.005428837 | 2012 | NA | 9 | 4594919 | C | G |
| rs301443 | 20410850 | 6505 | SLC1A1 | umls:C0029421 | BeFree | Interestingly, the strongest association in OCD has been found at rs301443 (P=0.000067) residing between SLC1A1 and JMJD2C at 9p24. | 0.005428837 | 2010 | NA | 9 | 4594919 | C | G |
| rs361525 | 22311210 | 7124 | TNF | umls:C0029421 | BeFree | We found that the A allele of the TNFA rs361525 polymorphism was significantly associated with OCD subjects, according to the allelic χ(2) association test (p=0.007). | 0.000542884 | 2012 | TNF | 6 | 31575324 | G | A |
| rs386602276 | 18191318 | 3356 | HTR2A | umls:C0029421 | BeFree | The purpose of this study is to investigate the association between four serotonergic polymorphisms (STin2 VNTR and 5-HTTLPR of the SLC6A4 gene, and A-1438G (rs6311) and T102C (rs6313) of the HTR2A gene) and OCD. | 0.002985861 | 2008 | NA | NA | NA | NA | NA |
| rs386602276 | 16910371 | 3356 | HTR2A | umls:C0029421 | BeFree | Both genotypic and allelic distributions of the 5-HT receptor 2A (5-HT2A) T102C variant were found to be significantly different between the TTM and control subjects (p=0.028 and p=0.024, respectively), and a trend towards significance was noted between the TTM and OCD subjects (p=0.084 and p=0.080 for genotype and allele analyses, respectively), with the T102T-genotype found to confer susceptibility to the development of TTM. | 0.002985861 | 2006 | NA | NA | NA | NA | NA |
| rs4680 | 16043283 | 1312 | COMT | umls:C0029421 | BeFree | These results do not support the hypothesis that the COMT Val158Met gene polymorphism is associated with liability to schizophrenia-OCD. | 0.005157396 | 2005 | COMT;MIR4761 | 22 | 19963748 | G | A |
| rs4680 | 19398820 | 1312 | COMT | umls:C0029421 | BeFree | The data here are consistent with previous work delineating the different symptom subtypes of OCD, also with previous work suggesting that the Met/Met (L/L) genotype of the COMT Val158Met polymorphism may be associated with anxiety symptoms, as well as with previous work suggesting that dopaminergic genes may be particularly important in early-onset OCD. | 0.005157396 | 2008 | COMT;MIR4761 | 22 | 19963748 | G | A |
| rs4680 | 16187774 | 1312 | COMT | umls:C0029421 | BeFree | In subjects of Afrikaner descent, the L/L genotype of the COMT Val158Met polymorphism was significantly more common in the OCD hoarding group, with a preponderance of low activity alleles, compared with nonhoarding patients and controls. | 0.005157396 | 2005 | COMT;MIR4761 | 22 | 19963748 | G | A |
| rs4825476 | 23337130 | 121278 | TPH2 | umls:C0029421 | BeFree | Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD. | 0.000814326 | 2012 | GRIA3 | X | 123307628 | G | A |
| rs4825476 | 23337130 | 10215 | OLIG2 | umls:C0029421 | BeFree | Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD. | 0.000542884 | 2012 | GRIA3 | X | 123307628 | G | A |
| rs4825476 | 23337130 | 1007 | CDH9 | umls:C0029421 | BeFree | Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD. | 0.000271442 | 2012 | GRIA3 | X | 123307628 | G | A |
| rs4825476 | 23337130 | 2892 | GRIA3 | umls:C0029421 | BeFree | Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD. | 0.000271442 | 2012 | GRIA3 | X | 123307628 | G | A |
| rs6311 | 18191318 | 3356 | HTR2A | umls:C0029421 | BeFree | The purpose of this study is to investigate the association between four serotonergic polymorphisms (STin2 VNTR and 5-HTTLPR of the SLC6A4 gene, and A-1438G (rs6311) and T102C (rs6313) of the HTR2A gene) and OCD. | 0.002985861 | 2008 | HTR2A | 13 | 46897343 | C | T |
| rs6311 | 17241828 | 3356 | HTR2A | umls:C0029421 | BeFree | Nominally significant association was found at the HTR2A rs6311 polymorphism in subjects with tic disorder and OCD (p = .05), replicating a previous finding in Tourette syndrome and OCD. | 0.002985861 | 2007 | HTR2A | 13 | 46897343 | C | T |
| rs6313 | 18191318 | 3356 | HTR2A | umls:C0029421 | BeFree | The purpose of this study is to investigate the association between four serotonergic polymorphisms (STin2 VNTR and 5-HTTLPR of the SLC6A4 gene, and A-1438G (rs6311) and T102C (rs6313) of the HTR2A gene) and OCD. | 0.002985861 | 2008 | HTR2A | 13 | 46895805 | G | A |
| rs6313 | 16910371 | 3356 | HTR2A | umls:C0029421 | BeFree | Both genotypic and allelic distributions of the 5-HT receptor 2A (5-HT2A) T102C variant were found to be significantly different between the TTM and control subjects (p=0.028 and p=0.024, respectively), and a trend towards significance was noted between the TTM and OCD subjects (p=0.084 and p=0.080 for genotype and allele analyses, respectively), with the T102T-genotype found to confer susceptibility to the development of TTM. | 0.002985861 | 2006 | HTR2A | 13 | 46895805 | G | A |
| rs6766410 | 23928294 | 170572 | HTR3C | umls:C0029421 | BeFree | In male subjects, the variant rs6766410 (p.N163K) located in the HTR3C was significantly associated with OCD (p=0.007). | 0.000271442 | 2013 | HTR3C | 3 | 184056974 | C | A |
GWASdb Annotation(Total Genotypes:0) | |
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GWASdb Snp Trait(Total Genotypes:0) | |
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Mapped by lexical matching(Total Items:0) |
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Mapped by homologous gene(Total Items:0) |
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Chemical(Total Drugs:0) | |
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FDA approved drug and dosage information(Total Drugs:0) | |
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FDA labeling changes(Total Drugs:0) | |
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