PedAM
Pediatric Disease Annotations & Medicines
| oppositional defiant disorder | ||||
| Disease ID | 1812 |
|---|---|
| Disease | oppositional defiant disorder |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:8) HP:0000752 | Hyperactive behavior | 2 HP:0000708 | Behavioral problems | 2 HP:0007018 | Attention deficits | 2 HP:0000718 | Aggressive behaviour | 2 HP:0001249 | Mental retardation | 2 HP:0000739 | Anxiety | 1 HP:0000716 | Depression | 1 HP:0100710 | Impulsivity | 1 |
| Disease ID | 1812 |
|---|---|
| Disease | oppositional defiant disorder |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:2) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs4680 | 22270685 | 1312 | COMT | umls:C0029121 | BeFree | COMT Val(158)Met polymorphism has been associated with both symptoms of attention-deficit/hyperactivity disorder (ADHD) and disruptive behavior disorders (DBD): that is, oppositional defiant disorder (ODD) and conduct disorder (CD) often comorbid with ADHD. | 0.002909916 | 2012 | COMT;MIR4761 | 22 | 19963748 | G | A |
| rs6195 | 23055001 | 2908 | NR3C1 | umls:C0029121 | BeFree | A specific haplotype (G:A:G:G; ER22/23EK- N363S- BclI- A3669G) of NR3C1 showed a significant association with behaviors related to ADHD (particularly thought and attention problems, aggressive behavior), comorbidity with oppositional defiant disorder, and executive function domains. | 0.000271442 | 2013 | NA | NA | NA | NA | NA |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
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| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
Chemical(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA approved drug and dosage information(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
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| (Waiting for update.) | |