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PedAM

Pediatric Disease Annotations & Medicines



   open-angle glaucoma
  

Disease ID 168
Disease open-angle glaucoma
Definition
Glaucoma in which the angle of the anterior chamber is open and the trabecular meshwork does not encroach on the base of the iris.
Synonym
angle glaucoma open
compensated glaucoma
compensated glaucomas
compensative glaucoma
compensative glaucomas
glaucoma pigmentary
glaucoma simple
glaucoma simplex
glaucoma, compensated
glaucoma, compensative
glaucoma, noncongestive
glaucoma, open angle
glaucoma, open-angle
glaucoma, open-angle [disease/finding]
glaucoma, pigmentary
glaucoma, simple
glaucomas, compensated
glaucomas, compensative
glaucomas, open angle
glaucomas, open-angle
glaucomas, pigmentary
glaucomas, simple
oag - open-angle glaucoma
open angle glaucoma
open angle glaucomas
open cleft glaucoma
open-angle glaucoma (disorder)
open-angle glaucoma nos
open-angle glaucoma nos (disorder)
open-angle glaucoma, nos
open-angle glaucoma, unspecified
open-angle glaucomas
pigment dispersion syndrome
pigmentary glaucoma
pigmentary glaucoma (disorder)
pigmentary glaucomas
pigmentary open-angle glaucoma
simple glaucoma
simple glaucomas
simplex glaucoma
simplex, glaucoma
simplices, glaucoma
unspecified open-angle glaucoma
unspecified open-angle glaucoma (disorder)
wide-angle glaucoma
wide-angle glaucoma nos
wide-angle glaucoma, nos
OMIM
DOID
UMLS
C0017612
MeSH
SNOMED-CT
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:47)
C0017601  |  glaucoma  |  12
C0028840  |  ocular hypertension  |  11
C0020538  |  hypertension  |  11
C0011847  |  diabetes  |  8
C0456909  |  blindness  |  8
C0036454  |  visual field defect  |  7
C0086543  |  cataract  |  6
C0036454  |  visual field defects  |  5
C0011849  |  diabetes mellitus  |  4
C0036454  |  visual field loss  |  3
C0027092  |  myopia  |  3
C0152136  |  normal tension glaucoma  |  3
C0314719  |  dry eye  |  2
C0497327  |  dementia  |  2
C0029132  |  optic neuropathy  |  2
C0027961  |  ota's nevus  |  1
C0917796  |  leber's hereditary optic neuropathy  |  1
C0029124  |  optic nerve atrophy  |  1
C0544008  |  corneal endothelial dystrophy  |  1
C0037315  |  sleep apnea  |  1
C0520679  |  obstructive sleep apnea  |  1
C0027961  |  nevus of ota  |  1
C0035305  |  retinal detachments  |  1
C0442874  |  neuropathy  |  1
C0456909  |  vision loss  |  1
C0520679  |  obstructive sleep apnoea  |  1
C0028754  |  obesity  |  1
C0013238  |  dry eye syndrome  |  1
C0037315  |  sleep apnoea syndrome  |  1
C0011603  |  dermatitis  |  1
C0520679  |  obstructive sleep apnoea syndrome  |  1
C0037315  |  sleep apnoea  |  1
C0011615  |  atopic dermatitis  |  1
C0020676  |  hypothyroidism  |  1
C0035455  |  rhinitis  |  1
C0011884  |  diabetic retinopathy  |  1
C0206368  |  exfoliation syndrome  |  1
C0022073  |  heterochromic cyclitis  |  1
C0020758  |  lamellar ichthyosis  |  1
C0035305  |  retinal detachment  |  1
C2607914  |  allergic rhinitis  |  1
C0206368  |  pseudoexfoliation syndrome  |  1
C0035309  |  retinopathy  |  1
C0032285  |  pneumoniae  |  1
C0029132  |  optic neuropathies  |  1
C0206368  |  exfoliation glaucoma  |  1
C0206368  |  pseudoexfoliation glaucoma  |  1
Curated Gene
Entrez_id | Symbol | Resource(Total Genes:6)
PTGS2  |  5743  |  CTD_human
TMCO1  |  54499  |  CTD_human
CDKN2B-AS1  |  100048912  |  CTD_human
CAV1  |  857  |  CTD_human
CAV2  |  858  |  CTD_human
GPDS1  |  7986  |  OMIM
Inferring Gene
Entrez_id | Symbol | Resource(Total Genes:48)
1636  |  ACE  |  infer
153  |  ADRB1  |  infer
154  |  ADRB2  |  infer
348  |  APOE  |  infer
358  |  AQP1  |  infer
857  |  CAV1  |  infer
858  |  CAV2  |  infer
1026  |  CDKN1A  |  infer
1030  |  CDKN2B  |  infer
1295  |  COL8A1  |  infer
1296  |  COL8A2  |  infer
1545  |  CYP1B1  |  infer
1592  |  CYP26A1  |  infer
2068  |  ERCC2  |  infer
2288  |  FKBP4  |  infer
2289  |  FKBP5  |  infer
2944  |  GSTM1  |  infer
2950  |  GSTP1  |  infer
2952  |  GSTT1  |  infer
3552  |  IL1A  |  infer
3553  |  IL1B  |  infer
4016  |  LOXL1  |  infer
55669  |  MFN1  |  infer
9927  |  MFN2  |  infer
4653  |  MYOC  |  infer
344148  |  NCKAP5  |  infer
2908  |  NR3C1  |  infer
4976  |  OPA1  |  infer
10133  |  OPTN  |  infer
55486  |  PARL  |  infer
84898  |  PLXDC2  |  infer
5962  |  RDX  |  infer
100270952  |  RPL21P27  |  infer
654371  |  RPS15AP4  |  infer
5054  |  SERPINE1  |  infer
57282  |  SLC4A10  |  infer
64089  |  SNX16  |  infer
6648  |  SOD2  |  infer
6678  |  SPARC  |  infer
7040  |  TGFB1  |  infer
7099  |  TLR4  |  infer
160335  |  TMTC2  |  infer
7124  |  TNF  |  infer
7132  |  TNFRSF1A  |  infer
7157  |  TP53  |  infer
134430  |  WDR36  |  infer
7515  |  XRCC1  |  infer
57829  |  ZP4  |  infer
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:410)
100048912  |  CDKN2B-AS1  |  DISEASES
9957  |  HS3ST1  |  DISEASES
4653  |  MYOC  |  DISEASES
4653  |  MYOC  |  DISEASES
1634  |  DCN  |  DISEASES
29850  |  TRPM5  |  DISEASES
51052  |  PRLH  |  DISEASES
55711  |  FAR2  |  DISEASES
368  |  ABCC6  |  DISEASES
7049  |  TGFBR3  |  DISEASES
1414  |  CRYBB1  |  DISEASES
1690  |  COCH  |  DISEASES
7076  |  TIMP1  |  DISEASES
4313  |  MMP2  |  DISEASES
51285  |  RASL12  |  DISEASES
6422  |  SFRP1  |  DISEASES
79735  |  TBC1D17  |  DISEASES
7040  |  TGFB1  |  DISEASES
5444  |  PON1  |  DISEASES
5445  |  PON2  |  DISEASES
858  |  CAV2  |  DISEASES
5118  |  PCOLCE  |  DISEASES
5054  |  SERPINE1  |  DISEASES
113263  |  GLCCI1  |  DISEASES
6347  |  CCL2  |  DISEASES
1277  |  COL1A1  |  DISEASES
8683  |  SRSF9  |  DISEASES
9896  |  FIG4  |  DISEASES
9450  |  LY86  |  DISEASES
4015  |  LOX  |  DISEASES
6678  |  SPARC  |  DISEASES
56920  |  SEMA3G  |  DISEASES
8440  |  NCK2  |  DISEASES
8317  |  CDC7  |  DISEASES
1509  |  CTSD  |  DISEASES
6185  |  RPN2  |  DISEASES
63923  |  TNN  |  DISEASES
2700  |  GJA3  |  DISEASES
6626  |  SNRPA  |  DISEASES
652  |  BMP4  |  DISEASES
23163  |  GGA3  |  DISEASES
23550  |  PSD4  |  DISEASES
6495  |  SIX1  |  DISEASES
3315  |  HSPB1  |  DISEASES
2952  |  GSTT1  |  DISEASES
23639  |  LRRC6  |  DISEASES
64428  |  NARFL  |  DISEASES
29775  |  CARD10  |  DISEASES
2006  |  ELN  |  DISEASES
348  |  APOE  |  DISEASES
10439  |  OLFM1  |  DISEASES
22856  |  CHSY1  |  DISEASES
6538  |  SLC6A11  |  DISEASES
9201  |  DCLK1  |  DISEASES
759  |  CA1  |  DISEASES
51124  |  IER3IP1  |  DISEASES
2947  |  GSTM3  |  DISEASES
2799  |  GNS  |  DISEASES
29109  |  FHOD1  |  DISEASES
3569  |  IL6  |  DISEASES
10010  |  TANK  |  DISEASES
10850  |  CCL27  |  DISEASES
7057  |  THBS1  |  DISEASES
1545  |  CYP1B1  |  DISEASES
1545  |  CYP1B1  |  DISEASES
1295  |  COL8A1  |  DISEASES
2581  |  GALC  |  DISEASES
4016  |  LOXL1  |  DISEASES
4016  |  LOXL1  |  DISEASES
4053  |  LTBP2  |  DISEASES
4092  |  SMAD7  |  DISEASES
6505  |  SLC1A1  |  DISEASES
4969  |  OGN  |  DISEASES
7077  |  TIMP2  |  DISEASES
25939  |  SAMHD1  |  DISEASES
7515  |  XRCC1  |  DISEASES
10133  |  OPTN  |  DISEASES
10133  |  OPTN  |  DISEASES
5588  |  PRKCQ  |  DISEASES
829  |  CAPZA1  |  DISEASES
7353  |  UFD1L  |  DISEASES
55686  |  MREG  |  DISEASES
3552  |  IL1A  |  DISEASES
3553  |  IL1B  |  DISEASES
51430  |  SUCO  |  DISEASES
55133  |  SRBD1  |  DISEASES
8673  |  VAMP8  |  DISEASES
55850  |  USE1  |  DISEASES
55669  |  MFN1  |  DISEASES
941  |  CD80  |  DISEASES
941  |  CD80  |  DISEASES
55325  |  UFSP2  |  DISEASES
11107  |  PRDM5  |  DISEASES
93145  |  OLFM2  |  DISEASES
11063  |  SOX30  |  DISEASES
1462  |  VCAN  |  DISEASES
6507  |  SLC1A3  |  DISEASES
5218  |  CDK14  |  DISEASES
1795  |  DOCK3  |  DISEASES
7078  |  TIMP3  |  DISEASES
4060  |  LUM  |  DISEASES
170691  |  ADAMTS17  |  DISEASES
7157  |  TP53  |  DISEASES
6647  |  SOD1  |  DISEASES
81794  |  ADAMTS10  |  DISEASES
29967  |  LRP12  |  DISEASES
1030  |  CDKN2B  |  DISEASES
9712  |  USP6NL  |  DISEASES
79175  |  ZNF343  |  DISEASES
932  |  MS4A3  |  DISEASES
2904  |  GRIN2B  |  DISEASES
1420  |  CRYGC  |  DISEASES
6695  |  SPOCK1  |  DISEASES
2697  |  GJA1  |  DISEASES
170692  |  ADAMTS18  |  DISEASES
25890  |  ABI3BP  |  DISEASES
760  |  CA2  |  DISEASES
57188  |  ADAMTSL3  |  DISEASES
6529  |  SLC6A1  |  DISEASES
7079  |  TIMP4  |  DISEASES
54953  |  C1orf27  |  DISEASES
4690  |  NCK1  |  DISEASES
9669  |  EIF5B  |  DISEASES
3837  |  KPNB1  |  DISEASES
10417  |  SPON2  |  DISEASES
1409  |  CRYAA  |  DISEASES
5822  |  PWP2  |  DISEASES
6271  |  S100A1  |  DISEASES
51475  |  CABP2  |  DISEASES
4041  |  LRP5  |  DISEASES
2487  |  FRZB  |  DISEASES
27306  |  HPGDS  |  DISEASES
26577  |  PCOLCE2  |  DISEASES
819  |  CAMLG  |  DISEASES
4846  |  NOS3  |  DISEASES
364  |  AQP7  |  DISEASES
26610  |  ELP4  |  DISEASES
4314  |  MMP3  |  DISEASES
26585  |  GREM1  |  DISEASES
4218  |  RAB8A  |  DISEASES
4597  |  MVD  |  DISEASES
558  |  AXL  |  DISEASES
4909  |  NTF4  |  DISEASES
9963  |  SLC23A1  |  DISEASES
8988  |  HSPB3  |  DISEASES
27085  |  MTBP  |  DISEASES
5729  |  PTGDR  |  DISEASES
23244  |  PDS5A  |  DISEASES
23244  |  PDS5A  |  DISEASES
5308  |  PITX2  |  DISEASES
5308  |  PITX2  |  DISEASES
171558  |  PTCRA  |  DISEASES
2783  |  GNB2  |  DISEASES
10791  |  VAMP5  |  DISEASES
649  |  BMP1  |  DISEASES
25998  |  IBTK  |  DISEASES
1296  |  COL8A2  |  DISEASES
10963  |  STIP1  |  DISEASES
378  |  ARF4  |  DISEASES
4968  |  OGG1  |  DISEASES
2720  |  GLB1  |  DISEASES
4493  |  MT1E  |  DISEASES
54205  |  CYCS  |  DISEASES
29984  |  RHOD  |  DISEASES
285590  |  SH3PXD2B  |  DISEASES
3265  |  HRAS  |  DISEASES
3265  |  HRAS  |  DISEASES
26502  |  NARF  |  DISEASES
25832  |  NBPF14  |  DISEASES
30008  |  EFEMP2  |  DISEASES
254263  |  CNIH2  |  DISEASES
358  |  AQP1  |  DISEASES
5870  |  RAB6A  |  DISEASES
2944  |  GSTM1  |  DISEASES
53832  |  IL20RA  |  DISEASES
1909  |  EDNRA  |  DISEASES
1191  |  CLU  |  DISEASES
23541  |  SEC14L2  |  DISEASES
138009  |  DCAF4L2  |  DISEASES
8904  |  CPNE1  |  DISEASES
27319  |  BHLHE22  |  DISEASES
80207  |  OPA3  |  DISEASES
10938  |  EHD1  |  DISEASES
8703  |  B4GALT3  |  DISEASES
8818  |  DPM2  |  DISEASES
160335  |  TMTC2  |  DISEASES
6330  |  SCN4B  |  DISEASES
64089  |  SNX16  |  DISEASES
4312  |  MMP1  |  DISEASES
10615  |  SPAG5  |  DISEASES
10954  |  PDIA5  |  DISEASES
55486  |  PARL  |  DISEASES
2200  |  FBN1  |  DISEASES
342898  |  SYCN  |  DISEASES
80821  |  DDHD1  |  DISEASES
633  |  BGN  |  DISEASES
284359  |  IZUMO1  |  DISEASES
11260  |  XPOT  |  DISEASES
53833  |  IL20RB  |  DISEASES
140460  |  ASB7  |  DISEASES
4990  |  SIX6  |  DISEASES
1946  |  EFNA5  |  DISEASES
286753  |  TUSC5  |  DISEASES
286753  |  TUSC5  |  DISEASES
115749  |  C12orf56  |  DISEASES
29110  |  TBK1  |  DISEASES
2192  |  FBLN1  |  DISEASES
6401  |  SELE  |  DISEASES
201475  |  RAB12  |  DISEASES
166752  |  FREM3  |  DISEASES
3916  |  LAMP1  |  DISEASES
5332  |  PLCB4  |  DISEASES
23180  |  RFTN1  |  DISEASES
283  |  ANG  |  DISEASES
150280  |  HORMAD2  |  DISEASES
8372  |  HYAL3  |  DISEASES
3824  |  KLRD1  |  DISEASES
64778  |  FNDC3B  |  DISEASES
473  |  RERE  |  DISEASES
2885  |  GRB2  |  DISEASES
857  |  CAV1  |  DISEASES
6540  |  SLC6A13  |  DISEASES
391  |  RHOG  |  DISEASES
7444  |  VRK2  |  DISEASES
60490  |  PPCDC  |  DISEASES
5170  |  PDPK1  |  DISEASES
9962  |  SLC23A2  |  DISEASES
100132406  |  NBPF10  |  DISEASES
6890  |  TAP1  |  DISEASES
64094  |  SMOC2  |  DISEASES
1413  |  CRYBA4  |  DISEASES
2331  |  FMOD  |  DISEASES
2202  |  EFEMP1  |  DISEASES
80781  |  COL18A1  |  DISEASES
4010  |  LMX1B  |  DISEASES
4010  |  LMX1B  |  DISEASES
144100  |  PLEKHA7  |  DISEASES
2073  |  ERCC5  |  DISEASES
9644  |  SH3PXD2A  |  DISEASES
5733  |  PTGER3  |  DISEASES
57194  |  ATP10A  |  DISEASES
50807  |  ASAP1  |  DISEASES
3698  |  ITIH2  |  DISEASES
5980  |  REV3L  |  DISEASES
799  |  CALCR  |  DISEASES
6539  |  SLC6A12  |  DISEASES
7037  |  TFRC  |  DISEASES
115294  |  PCMTD1  |  DISEASES
4519  |  MT-CYB  |  DISEASES
11214  |  AKAP13  |  DISEASES
9755  |  TBKBP1  |  DISEASES
9542  |  NRG2  |  DISEASES
4538  |  MT-ND4  |  DISEASES
4536  |  MT-ND2  |  DISEASES
56259  |  CTNNBL1  |  DISEASES
9578  |  CDC42BPB  |  DISEASES
4509  |  MT-ATP8  |  DISEASES
5693  |  PSMB5  |  DISEASES
9859  |  CEP170  |  DISEASES
57829  |  ZP4  |  DISEASES
8476  |  CDC42BPA  |  DISEASES
7042  |  TGFB2  |  DISEASES
3664  |  IRF6  |  DISEASES
6648  |  SOD2  |  DISEASES
26254  |  OPTC  |  DISEASES
481  |  ATP1B1  |  DISEASES
1805  |  DPT  |  DISEASES
1490  |  CTGF  |  DISEASES
1314  |  COPA  |  DISEASES
5824  |  PEX19  |  DISEASES
93183  |  PIGM  |  DISEASES
23493  |  HEY2  |  DISEASES
55974  |  SLC50A1  |  DISEASES
7170  |  TPM3  |  DISEASES
4881  |  NPR1  |  DISEASES
100288142  |  NBPF20  |  DISEASES
26227  |  PHGDH  |  DISEASES
4803  |  NGF  |  DISEASES
8266  |  UBL4A  |  DISEASES
8266  |  UBL4A  |  DISEASES
5309  |  PITX3  |  DISEASES
10451  |  VAV3  |  DISEASES
1301  |  COL11A1  |  DISEASES
118427  |  OLFM3  |  DISEASES
24  |  ABCA4  |  DISEASES
5737  |  PTGFR  |  DISEASES
5730  |  PTGDS  |  DISEASES
1289  |  COL5A1  |  DISEASES
7410  |  VAV2  |  DISEASES
186  |  AGTR2  |  DISEASES
7422  |  VEGFA  |  DISEASES
4318  |  MMP9  |  DISEASES
26508  |  HEYL  |  DISEASES
4520  |  MTF1  |  DISEASES
1025  |  CDK9  |  DISEASES
220202  |  ATOH7  |  DISEASES
26190  |  FBXW2  |  DISEASES
7099  |  TLR4  |  DISEASES
3710  |  ITPR3  |  DISEASES
5030  |  P2RY4  |  DISEASES
19  |  ABCA1  |  DISEASES
1889  |  ECE1  |  DISEASES
1306  |  COL15A1  |  DISEASES
63940  |  GPSM3  |  DISEASES
11240  |  PADI2  |  DISEASES
4237  |  MFAP2  |  DISEASES
10919  |  EHMT2  |  DISEASES
2159  |  F10  |  DISEASES
2155  |  F7  |  DISEASES
1282  |  COL4A1  |  DISEASES
7917  |  BAG6  |  DISEASES
9249  |  DHRS3  |  DISEASES
4878  |  NPPA  |  DISEASES
4524  |  MTHFR  |  DISEASES
11074  |  TRIM31  |  DISEASES
10218  |  ANGPTL7  |  DISEASES
7056  |  THBD  |  DISEASES
5457  |  POU4F1  |  DISEASES
84898  |  PLXDC2  |  DISEASES
6311  |  ATXN2  |  DISEASES
57449  |  PLEKHG5  |  DISEASES
10097  |  ACTR2  |  DISEASES
22903  |  BTBD3  |  DISEASES
5080  |  PAX6  |  DISEASES
5251  |  PHEX  |  DISEASES
5251  |  PHEX  |  DISEASES
1906  |  EDN1  |  DISEASES
3601  |  IL15RA  |  DISEASES
2762  |  GMDS  |  DISEASES
2296  |  FOXC1  |  DISEASES
2296  |  FOXC1  |  DISEASES
2971  |  GTF3A  |  DISEASES
10457  |  GPNMB  |  DISEASES
10457  |  GPNMB  |  DISEASES
60312  |  AFAP1  |  DISEASES
348801  |  LNP1  |  DISEASES
7306  |  TYRP1  |  DISEASES
7306  |  TYRP1  |  DISEASES
56953  |  NT5M  |  DISEASES
4017  |  LOXL2  |  DISEASES
53353  |  LRP1B  |  DISEASES
57634  |  EP400  |  DISEASES
1130  |  LYST  |  DISEASES
54828  |  BCAS3  |  DISEASES
163126  |  EID2  |  DISEASES
54499  |  TMCO1  |  DISEASES
136319  |  MTPN  |  DISEASES
10018  |  BCL2L11  |  DISEASES
6430  |  SRSF5  |  DISEASES
2875  |  GPT  |  DISEASES
655  |  BMP7  |  DISEASES
1781  |  DYNC1I2  |  DISEASES
7289  |  TULP3  |  DISEASES
23365  |  ARHGEF12  |  DISEASES
1415  |  CRYBB2  |  DISEASES
2950  |  GSTP1  |  DISEASES
54826  |  GIN1  |  DISEASES
10587  |  TXNRD2  |  DISEASES
2199  |  FBLN2  |  DISEASES
9718  |  ECE2  |  DISEASES
11078  |  TRIOBP  |  DISEASES
80204  |  FBXO11  |  DISEASES
9699  |  RIMS2  |  DISEASES
3778  |  KCNMA1  |  DISEASES
4052  |  LTBP1  |  DISEASES
729582  |  DIRC3  |  DISEASES
136371  |  ASB10  |  DISEASES
57282  |  SLC4A10  |  DISEASES
57448  |  BIRC6  |  DISEASES
130827  |  TMEM182  |  DISEASES
1029  |  CDKN2A  |  DISEASES
387836  |  CLEC2A  |  DISEASES
50863  |  NTM  |  DISEASES
960  |  CD44  |  DISEASES
7124  |  TNF  |  DISEASES
387  |  RHOA  |  DISEASES
83463  |  MXD3  |  DISEASES
84627  |  ZNF469  |  DISEASES
10908  |  PNPLA6  |  DISEASES
8522  |  GAS7  |  DISEASES
1154  |  CISH  |  DISEASES
627  |  BDNF  |  DISEASES
2801  |  GOLGA2  |  DISEASES
7045  |  TGFBI  |  DISEASES
85445  |  CNTNAP4  |  DISEASES
6256  |  RXRA  |  DISEASES
7881  |  KCNAB1  |  DISEASES
6171  |  RPL41  |  DISEASES
134430  |  WDR36  |  DISEASES
285605  |  DTWD2  |  DISEASES
149466  |  C1orf210  |  DISEASES
64641  |  EBF2  |  DISEASES
4147  |  MATN2  |  DISEASES
23741  |  EID1  |  DISEASES
7178  |  TPT1  |  DISEASES
60481  |  ELOVL5  |  DISEASES
4190  |  MDH1  |  DISEASES
100431172  |  KLRF2  |  DISEASES
83857  |  TMTC1  |  DISEASES
54749  |  EPDR1  |  DISEASES
3316  |  HSPB2  |  DISEASES
10896  |  OCLM  |  DISEASES
4782  |  NFIC  |  DISEASES
8153  |  RND2  |  DISEASES
7409  |  VAV1  |  DISEASES
100302740  |  FAS-AS1  |  DISEASES
352990  |  HCP5B  |  DISEASES
348120  |  LINC01193  |  DISEASES
4550  |  MT-RNR2  |  DISEASES
6053  |  RNR2  |  DISEASES
Locus(Waiting for update.)
Disease ID 168
Disease open-angle glaucoma
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:31)
HP:0000501  |  Glaucoma  |  12
HP:0000822  |  Hypertension  |  11
HP:0000618  |  Blindness  |  8
HP:0001123  |  Partial loss of field of vision  |  7
HP:0000518  |  Cataract  |  6
HP:0000819  |  Diabetes mellitus  |  4
HP:0012627  |  Pseudoexfoliation  |  4
HP:0000545  |  Near sightedness  |  3
HP:0011003  |  High myopia  |  3
HP:0002104  |  Absence of spontaneous respiration  |  2
HP:0010535  |  Sleep apnea  |  2
HP:0000726  |  Dementia  |  2
HP:0001138  |  Damaged optic nerve  |  2
HP:0007720  |  Flat cornea  |  1
HP:0000821  |  Underactive thyroid  |  1
HP:0012384  |  Nasal inflammation  |  1
HP:0000572  |  Visual loss  |  1
HP:0012416  |  Hypercarbia  |  1
HP:0001047  |  Atopic dermatitis  |  1
HP:0000575  |  Scotoma  |  1
HP:0000488  |  Noninflammatory retina disease  |  1
HP:0000505  |  Poor vision  |  1
HP:0002527  |  Falls  |  1
HP:0002870  |  Obstructive sleep apnea  |  1
HP:0009920  |  Congenital melanosis bulbi  |  1
HP:0003287  |  Abnormality of mitochondrial metabolism  |  1
HP:0000648  |  Optic-nerve degeneration  |  1
HP:0001513  |  Obesity  |  1
HP:0003764  |  Naevus  |  1
HP:0003193  |  Allergic rhinitis  |  1
HP:0000541  |  Detached retina  |  1
Disease ID 168
Disease open-angle glaucoma
Manually Symptom
UMLS  | Name(Total Manually Symptoms:13)
C0856169  |  endothelial dysfunction
C0730289  |  choroidal ischemia
C0595921  |  intraocular pressure
C0259749  |  autonomic neuropathy
C0235267  |  red eyes
C0206368  |  glaucoma capsulare
C0036454  |  visual field loss
C0036454  |  visual field defects
C0036454  |  visual field defect
C0036454  |  scotoma
C0034951  |  refractive errors
C0028840  |  ocular hypertension
C0019080  |  hemorrhage
Text Mined Symptom
UMLS | Name | Sentences' Count(Total Symptoms:6)
C0021888  |  intraocular pressure  |  47
C0028840  |  ocular hypertension  |  11
C0036454  |  visual field defect  |  5
C0036454  |  visual field loss  |  3
C0036454  |  visual field defects  |  2
C0036454  |  scotoma  |  1
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:14)
snpId pubmedId geneId geneSymbol diseaseId sourceId sentence score Year geneSymbol_dbSNP CHROMOSOME POS REF ALT
rs1063192224197381030CDKN2Bumls:C0017612GAD[A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma.]0.0029099162012CDKN2B;CDKN2B-AS1922003368GA
rs1063192228404861030CDKN2Bumls:C0017612BeFreeThe CDKN2B variant rs1063192 also was found to be associated more strongly with advanced OAG.0.0029099162012CDKN2B;CDKN2B-AS1922003368GA
rs112581941688518810133OPTNumls:C0017612BeFreeTo investigate the role of the common OPTN Met98Lys variant as a risk allele in open-angle glaucoma (OAG), autosomal dominant optic atrophy (ADOA) and Leber's hereditary optic neuropathy (LHON).0.0441601132006OPTN1013110400TA
rs162562211399741545CYP1B1umls:C0017612GAD[Although no major effect of common variation at the CYP1B1 locus on POAG was found, there could be an effect of SNPs tagged by rs162562 and represented on the AGCAGCC haplotype.]0.0417309492010CYP1B1;RMDN2238070372GT
rs17576208087304313MMP2umls:C0017612BeFreeFunctional gene polymorphisms of these MMPs such as MMP1 -1607 1G/2G (rs1799750), MMP2 -1306 C/T (rs243865), MMP2 -1575 G/A (rs243866), and MMP9 Q279R (rs17576) are thus plausible candidates as risk factors for open angle glaucomas.0.0005428842010MMP92046011586AG
rs1799750208087304313MMP2umls:C0017612BeFreeFunctional gene polymorphisms of these MMPs such as MMP1 -1607 1G/2G (rs1799750), MMP2 -1306 C/T (rs243865), MMP2 -1575 G/A (rs243866), and MMP9 Q279R (rs17576) are thus plausible candidates as risk factors for open angle glaucomas.0.0005428842010MMP1;WTAPP111102799765C-
rs243865208087304313MMP2umls:C0017612BeFreeFunctional gene polymorphisms of these MMPs such as MMP1 -1607 1G/2G (rs1799750), MMP2 -1306 C/T (rs243865), MMP2 -1575 G/A (rs243866), and MMP9 Q279R (rs17576) are thus plausible candidates as risk factors for open angle glaucomas.0.0005428842010MMP21655477894CT
rs243866208087304313MMP2umls:C0017612BeFreeFunctional gene polymorphisms of these MMPs such as MMP1 -1607 1G/2G (rs1799750), MMP2 -1306 C/T (rs243865), MMP2 -1575 G/A (rs243866), and MMP9 Q279R (rs17576) are thus plausible candidates as risk factors for open angle glaucomas.0.0005428842010MMP21655477625GA
rs3825942182549564016LOXL1umls:C0017612GAD[These results indicate that the G153D LOXL1 variant is significantly associated with an increased risk of pseudoexfoliation and pseudoexfoliation glaucoma in an ethnically diverse patient population from the Northeastern United States.]0.0350247282008LOXL1;LOXL1-AS11573927241GA
rs386545618253177174524MTHFRumls:C0017612BeFreeThe effect of MTHFR ala222val polymorphism on open-angle glaucoma: a meta-analysis.0.0258280422015NANANANANA
rs423660120835238858CAV2umls:C0017612GAD[Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma.]0.1223670322010NA7116522675GA
rs74315330187287514653MYOCumls:C0017612BeFreePro370Leu MYOC gene mutation in a large Chinese family with juvenile-onset open angle glaucoma: correlation between genotype and phenotype.0.1090093972008MYOC1171636331GA
rs74315336154520634653MYOCumls:C0017612BeFreeTo investigate mechanism(s) by which mutations in the olfactomedin domain of myocilin (MYOC), also known as the trabecular meshwork-induced glucocorticoid response (TIGR) gene, cause autosomal dominant open-angle glaucoma, the structure and properties of wild-type (WT) MYOC protein were examined, when expressed alone or simultaneously with the Q368X or K423E disease-associated polypeptides.0.1090093972004MYOC1171636173TC
rs758856722419738344148NCKAP5umls:C0017612GAD[A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma.]0.0023670322012NCKAP52133605461TC
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:384)
CHR POS SNPID REF ALT ORI_SNPID PMID P_VALUE P_VALUE_TEXT OR/BETA CI95_TEXT GWAS_INITIAL_SAMPLE_SIZE SUB_POPULATION SUPER_POPULATION GWAS_TRAIT HPO_ID HPO_TERM DO_ID DO_TERM MESH_ID MESH_TERM EFO_ID EFO_TERM DOLITE_TERM RISK_ALLELE PUBLICATION_TYPE AA GENE_SYMBOL TYPE REFGENE
165487083rs519282TGrs519282226059215.95E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTNA
171373738rs875727TCrs875727224197387.15E-19NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTPTGER3
1103379918rs3753841GArs3753841229228759.00E-10NA1.2NA984 Singaporean Chinese cases; 943 Singaporean Chinese controls; 297 Han Chinese cases; 1,044 Han Chinese controls; 573 South Asian ancestry cases; 3,065 Singaporean Malaysian controls; 2,538 Singaporean Indian controls; 2,018 Vietnamese ancestry controls.South Asian(573)Singaporean Malaysian(3065)Han Chinese(1341)Singaporean Indian(2538)Vietnamese(2018)Singaporean Chinese(1927)ALL(11462)ASN(8351)SAN(3111)ALL(11462)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190
1104852738rs10881542TCrs10881542229228752.00E-06NA1.18NA984 Singaporean Chinese cases; 943 Singaporean Chinese controls; 297 Han Chinese cases; 1,044 Han Chinese controls; 573 South Asian ancestry cases; 3,065 Singaporean Malaysian controls; 2,538 Singaporean Indian controls; 2,018 Vietnamese ancestry controls.South Asian(573)Singaporean Malaysian(3065)Han Chinese(1341)Singaporean Indian(2538)Vietnamese(2018)Singaporean Chinese(1927)ALL(11462)ASN(8351)SAN(3111)ALL(11462)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190
1106990083rs10881403TArs10881403226059214.24E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTNA
1107056847rs12045753GArs12045753226059211.62E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tANA
1107075244rs12025734GArs12025734226059216.17E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGNA
1107404931rs12024651GArs12024651226059216.36E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tANA
1179891565rs6689160AGrs6689160224280425.80E-08NANANA833 Japanese ancestry cases; 686 Japanese ancestry controlsJapanese(1519)ALL(1519)ASN(1519)ALL(1519)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNANAANA
1205122529rs12142514AGrs12142514226059212.68E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGDSTYK
1226826484rs10495246CArs10495246226059211.93E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCITPKB
1238096886rs547984ACrs547984196256186.00E-05Primary open-angle glaucomaNANA418 Japanese cases; 300 Japanese controlsJapanese(718)ALL(718)ASN(718)ALL(718)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTNA
1238097039rs540782CGrs540782196256186.00E-05Primary open-angle glaucomaNANA418 Japanese cases; 300 Japanese controlsJapanese(718)ALL(718)ASN(718)ALL(718)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
1238099090rs693421TGrs693421196256184.00E-05Primary open-angle glaucomaNANA418 Japanese cases; 300 Japanese controlsJapanese(718)ALL(718)ASN(718)ALL(718)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
1238104895rs2499601CTrs2499601196256189.00E-05Primary open-angle glaucomaNANA418 Japanese cases; 300 Japanese controlsJapanese(718)ALL(718)ASN(718)ALL(718)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tG,ANA
228358981rs2048047CTrs2048047226059212.96E-04NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tABRE
228497276rs6711937CTrs6711937226059216.78E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCBRE
228852926rs4530322AGrs4530322208352384.30E-06NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
240226489rs17024784TGrs17024784226059218.89E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTLOC100128590
245769170rs2082876CArs2082876226059214.28E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCSRBD1
2100864646rs12053126TArs12053126226059219.28E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTLOC150577
2100969067rs4850927AGrs4850927226059211.32E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tANA
2109498997rs765089TCrs765089208352386.40E-05NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
2109500929rs1478515CTrs1478515208352385.40E-05NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
2109501066rs1478516ACrs1478516208352385.30E-05NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
2109501066rs1478516ACrs1478516224197382.11E-04NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tANA
2134363032rs7588567TCrs7588567224197384.00E-07NA1.18[1.10-1.25] 1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomars7588567-GResearch Support, Non-U.S. Gov'tTNA
2197970654rs7559008CTrs7559008226059218.56E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCANKRD44
2205803372rs2194513AGrs2194513208352384.50E-05NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
2224696267rs7558186GTrs7558186224197386.50E-04NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGAP1S3
2230214932rs9288645TCrs9288645224197382.89E-04NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
31827768rs11128846CTrs11128846226059214.18E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
352295895rs7614727CTrs7614727226059212.08E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTWDR82
362477699rs9871763CArs9871763226059213.34E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tACADPS
362562709rs11130888CA,G,Trs11130888226059216.96E-07NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCCADPS
372217198rs9816781GArs9816781226059216.08E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGLOC201617
3148554759rs3772601TCrs3772601226059214.67E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tACPB1
423885568rs12500214GArs12500214226059213.00E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGPPARGC1A
423984463rs13119672TCrs13119672226059216.92E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
434424948rs10019658AGrs10019658226059218.59E-07NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tANA
437357559rs1002363AGrs1002363226059216.98E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tAKIAA1239
455490810rs17084534CTrs17084534226059211.04E-04NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
455494179rs17084542GArs17084542226059216.63E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGNA
459667025rs10517449TCrs10517449224197381.82E-04NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTNA
4129160316rs4975300TCrs4975300224197384.48E-04NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTNA
4146722324rs9998097CTrs9998097226059211.87E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCZNF827
4164466824rs13130399CTrs13130399226059214.26E-04NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCMARCH1
4164560851rs13123027CTrs13123027226059211.69E-04NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTMARCH1
4182470191rs11132079TCrs11132079224197388.81E-04NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTNA
55307913rs41524744TCrs41524744224280424.70E-08NANANA833 Japanese ancestry cases; 686 Japanese ancestry controlsJapanese(1519)ALL(1519)ASN(1519)ALL(1519)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNANATADAMTS16
555978051rs16886018CArs16886018226059217.12E-07NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tANA
558291208rs12657171CTrs12657171226059213.26E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCPDE4D
576726202rs2114950AGrs2114950229228753.38E-04NANANA984 Singaporean Chinese cases; 943 Singaporean Chinese controls; 297 Han Chinese cases; 1,044 Han Chinese controls; 573 South Asian ancestry cases; 3,065 Singaporean Malaysiansian controls; 2,538 Singaporean Indian controls; 2,018 Vietnamese ancestry controls.South Asian(573)Singaporean Malaysian(3065)Han Chinese(1341)Singaporean Indian(2538)Vietnamese(2018)Singaporean Chinese(1927)ALL(11462)ASN(8351)SAN(3111)ALL(11462)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190
582123527rs11952923CGrs11952923226059213.22E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
597315918rs1363886TCrs1363886208352382.10E-05NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
5103104452rs1820121TCrs1820121208352388.30E-06NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
5103129506rs1345621ACrs1345621208352384.40E-06NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
5117116443rs12110276AC,G,Trs12110276226059215.26E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
5144074365rs10058739GArs10058739226059212.06E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGNA
611276028rs11961171GArs11961171226059218.55E-13NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tANEDD9
611329423rs967473GArs967473226059211.67E-04NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNEDD9
611703500rs9366868GA,C,Trs9366868226059212.59E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGNA
614358016rs4715889ATrs4715889226059218.17E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tT,ANA
646457836rs4711853AGrs4711853208352381.90E-05NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
680109143rs11754426TCrs11754426226059219.29E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTNA
683590891rs13206195CTrs13206195226059219.60E-07NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tT,CNA
6120750709rs4946483TCrs4946483226059211.57E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
6131097518rs9375768TGrs9375768226059213.49E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTNA
6160113321rs2842960CTrs2842960226059216.42E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCSOD2
732461262rs7785999CArs7785999226059219.22E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
733604021rs1020516CTrs1020516226059218.07E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tABBS9
7116137892rs4730742TGrs4730742208352385.80E-05NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
7116148370rs1052990TGrs1052990208352381.10E-09NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
7116162729rs4236601GArs4236601208352382.00E-11NA1.27[1.18-1.36]1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomars4236601-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
7131380008rs4076505TCrs4076505226059213.65E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGNA
7138076980rs2047234CTrs2047234208352381.30E-05NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
7138677481rs7797152CTrs7797152226059212.23E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTNA
7158385584rs12532121GArs12532121226059211.55E-04NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGNA
81702911rs6558527TGrs6558527226059212.25E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGNA
84467788rs2617104GCrs2617104226059219.15E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCCSMD1
89556847rs7010270GArs7010270226059212.50E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tATNKS
816817433rs823600GTrs823600208352383.40E-05NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
817028091rs730243CArs730243226059215.56E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCZDHHC2
852716137rs6990379GArs6990379226059218.39E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGPXDNL
852887541rs1015213CTrs1015213229228753.00E-09NA1.5NA984 Singaporean Chinese cases; 943 Singaporean Chinese controls; 297 Han Chinese cases; 1,044 Han Chinese controls; 573 South Asian ancestry cases; 3,065 Singaporean Malaysian controls; 2,538 Singaporean Indian controls; 2,018 Vietnamese ancestry controls.South Asian(573)Singaporean Malaysian(3065)Han Chinese(1341)Singaporean Indian(2538)Vietnamese(2018)Singaporean Chinese(1927)ALL(11462)ASN(8351)SAN(3111)ALL(11462)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190
870237924rs6983293TCrs6983293224197383.66E-04NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTNA
870576130rs4738017GTrs4738017208352385.10E-05NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
8105956843rs1851292TCrs1851292225706176.92E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8105957432rs284487CTrs284487225706176.92E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8105957464rs284488AGrs284488225706176.92E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8105958020rs284489AGrs284489225706179.00E-10NPG1.61[1.39-1.89]3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8105958196rs284490ACrs284490225706176.92E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8105958633rs284491CTrs284491225706179.71E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8105959600rs284492CTrs284492225706171.42E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8105965578rs284495TCrs284495225706171.42E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8105965737rs284496ACrs284496225706171.67E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8105966757rs1521771ATrs1521771225706172.26E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8105966760rs1521772AGrs1521772225706171.42E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8105978990rs1521774GArs1521774225706171.19E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8105982203rs10106029AGrs10106029225706176.03E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
8136850054rs4385494TGrs4385494226059214.51E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTNA
98924197rs9299077CTrs9299077226059212.88E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tT,CPTPRD
920603364rs2775264CTrs2775264226059218.84E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGMLLT3
920666605rs17831954CTrs17831954226059219.99E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCKIAA1797
921812720rs10811624CTrs10811624226059215.08E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCMTAP
921974218rs3731239AGrs3731239224197382.44E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTCDKN2A
921997015rs61271866TArs61271866224197381.01E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTCDKN2B-AS1
921997872rs3218020GArs3218020225706173.06E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
921999328rs2811713GArs2811713224197389.27E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGCDKN2B-AS1
921999328rs2811713GArs2811713225706174.47E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
921999328rs572101477GTATGTGrs2811713224197389.27E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGCDKN2B-AS1
921999328rs572101477GTATGTGrs2811713225706174.47E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922003223rs3217992CTrs3217992225706171.48E-11NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922003223rs3217992CTrs3217992226059212.55E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGCDKN2B
922003367rs1063192GArs1063192224197385.00E-11NA1.33[1.22-1.43]1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomars1063192-TResearch Support, Non-U.S. Gov'tTCDKN2B
922003367rs1063192GArs1063192225706179.67E-15NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922009698rs2069418GCrs2069418224197381.96E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGCDKN2B-AS1
922009698rs2069418GCrs2069418225706171.31E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922010004rs2069416TA,Grs2069416225706175.78E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922011642rs573687GArs573687224197382.11E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCCDKN2B-AS1
922011642rs573687GArs573687225706175.64E-13NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922012051rs13298881TCrs13298881225706171.47E-05NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922012422rs545226GArs545226225706172.82E-07NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922013411rs10811640GTrs10811640225706171.43E-08NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922013805rs10757263CTrs10757263225706171.31E-08NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922014137rs10811641CGrs10811641225706177.35E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922015465rs1101330CArs1101330224197382.68E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGCDKN2B-AS1
922015997rs1101329CTrs1101329224197381.20E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGCDKN2B-AS1
922016510rs62556546CGrs62556546224197383.11E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCCDKN2B-AS1
922017101rs2106120GTrs2106120225706171.29E-08NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922017550rs2106119AGrs2106119225706171.26E-08NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922017836rs643319CArs643319224280421.50E-06NANANA833 Japanese ancestry cases; 686 Japanese ancestry controlsJapanese(1519)ALL(1519)ASN(1519)ALL(1519)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNANATCDKN2B-AS1
922017836rs643319CArs643319225706171.08E-08NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922018781rs7044859TArs7044859224280422.30E-06NANANA833 Japanese ancestry cases; 686 Japanese ancestry controlsJapanese(1519)ALL(1519)ASN(1519)ALL(1519)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNANATCDKN2B-AS1
922018781rs7044859TArs7044859225706172.67E-08NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922019129rs523096AGrs523096224197381.43E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTCDKN2B-AS1
922019129rs523096AGrs523096224280423.80E-09NANANA833 Japanese ancestry cases; 686 Japanese ancestry controlsJapanese(1519)ALL(1519)ASN(1519)ALL(1519)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNANATCDKN2B-AS1
922019129rs523096AGrs523096225706174.40E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922019673rs518394GCrs518394224197381.41E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCCDKN2B-AS1
922019673rs518394GCrs518394224280425.20E-09NANANA833 Japanese ancestry cases; 686 Japanese ancestry controlsJapanese(1519)ALL(1519)ASN(1519)ALL(1519)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNANACCDKN2B-AS1
922019673rs518394GCrs518394225706174.40E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922019732rs10757264AGrs10757264224280421.60E-06NANANA833 Japanese ancestry cases; 686 Japanese ancestry controlsJapanese(1519)ALL(1519)ASN(1519)ALL(1519)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNANAACDKN2B-AS1
922021172rs597816TCrs597816224197381.56E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tACDKN2B-AS1
922021172rs597816TCrs597816225706173.11E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922021615rs568447GArs568447225706171.38E-08NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922021737rs567453GCrs567453225706179.14E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922022376rs581876CTrs581876225706171.82E-11NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922023795rs10965212TArs10965212225706172.72E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922024023rs504318ATrs504318225706171.25E-08NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922024351rs496892CTrs496892225706171.25E-08NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922024966rs10811643AGrs10811643225706171.70E-08NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922025067rs10811644ATrs10811644225706171.70E-08NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922025240rs7035484CGrs7035484225706178.41E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922025493rs10738604GArs10738604225706176.64E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922026077rs615552TCrs615552224197381.91E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tACDKN2B-AS1
922026077rs615552TCrs615552225706174.85E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922026594rs613312GArs613312224197381.98E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCCDKN2B-AS1
922026594rs613312GArs613312225706171.38E-12NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922026639rs543830ATrs543830224197382.00E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTCDKN2B-AS1
922026639rs543830ATrs543830225706173.64E-12NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922026834rs1591136GCrs1591136225706172.72E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922027402rs599452GArs599452224197382.06E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCCDKN2B-AS1
922027402rs599452GArs599452225706173.25E-12NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922028406rs62560774CArs62560774224197382.20E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCCDKN2B-AS1
922028801rs7049105AGrs7049105224280421.80E-05NANANA833 Japanese ancestry cases; 686 Japanese ancestry controlsJapanese(1519)ALL(1519)ASN(1519)ALL(1519)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNANAACDKN2B-AS1
922028801rs7049105AGrs7049105225706177.38E-14NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922029080rs679038GArs679038224197382.23E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCCDKN2B-AS1
922029080rs679038GArs679038225706173.25E-12NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922029445rs10965215GArs10965215224280422.50E-06NANANA833 Japanese ancestry cases; 686 Japanese ancestry controlsJapanese(1519)ALL(1519)ASN(1519)ALL(1519)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNANAGCDKN2B-AS1
922029445rs10965215GArs10965215225706171.34E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922029547rs564398TCrs564398224197382.22E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tACDKN2B-AS1
922029547rs564398TCrs564398224280424.60E-09NANANA833 Japanese ancestry cases; 686 Japanese ancestry controlsJapanese(1519)ALL(1519)ASN(1519)ALL(1519)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNANAACDKN2B-AS1
922029547rs564398TCrs564398225706171.24E-12NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922030027rs4977753CTrs4977753225706171.16E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922031005rs7865618GArs7865618224197382.20E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tACDKN2B-AS1
922031005rs7865618GArs7865618224280429.00E-11NA1.78[1.50-2.12]833 Japanese ancestry cases; 686 Japanese ancestry controlsJapanese(1519)ALL(1519)ASN(1519)ALL(1519)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomars7865618-ANAACDKN2B-AS1
922031005rs7865618GArs7865618225706172.48E-13NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922032119rs10115049AGrs10115049225706172.30E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922032152rs634537TGrs634537224197382.18E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tACDKN2B-AS1
922032152rs634537TGrs634537225706171.24E-12NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922033366rs2157719CTrs2157719224197382.09E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGCDKN2B-AS1
922033366rs2157719CTrs2157719225706171.00E-12NPG1.72[1.49-2.00] 3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922033366rs2157719CTrs2157719225706172.00E-18NA1.45[1.33-1.59] 3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922034719rs2151280GArs2151280225706171.87E-13NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922036112rs1008878GTrs1008878224197382.04E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTCDKN2B-AS1
922036112rs1008878GTrs1008878225706171.44E-12NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922036367rs1556515CTrs1556515224197382.04E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tACDKN2B-AS1
922036367rs1556515CTrs1556515225706171.29E-12NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922040765rs1333037CTrs1333037224197381.96E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tACDKN2B-AS1
922040765rs1333037CTrs1333037225706171.29E-12NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922041443rs1360590TCrs1360590225706175.42E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922043612rs1412830CTrs1412830224197381.92E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGCDKN2B-AS1
922043612rs1412830CTrs1412830225706172.66E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922043819rs1333036TCrs1333036225706172.24E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922043926rs1412829AGrs1412829224197381.91E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTCDKN2B-AS1
922043926rs1412829AGrs1412829225706172.95E-15NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922045317rs1360589CTrs1360589224197381.90E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tACDKN2B-AS1
922045317rs1360589CTrs1360589225706171.14E-11NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922047945rs10120806TCrs10120806224197385.00E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCCDKN2B-AS1
922047945rs10120806TCrs10120806225706178.38E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922048391rs7027950CTrs7027950225706178.16E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922048414rs7028268GArs7028268225706171.25E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922048683rs7028570GArs7028570225706178.16E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922048859rs10757265TCrs10757265225706178.16E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922049130rs10738605CA,Grs10738605225706178.16E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922049555rs10757266CTrs10757266225706178.16E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922049656rs10811645GArs10811645224197385.02E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tACDKN2B-AS1
922049656rs10811645GArs10811645225706178.16E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922050613rs944799AGrs944799225706178.16E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922050898rs944800AGrs944800224197381.89E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGCDKN2B-AS1
922050898rs944800AGrs944800225706173.44E-11NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922051670rs944801GCrs944801224197381.73E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCCDKN2B-AS1
922051670rs944801GCrs944801225706171.27E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922052734rs6475604TCrs6475604224197381.88E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCCDKN2B-AS1
922052734rs6475604TCrs6475604225706171.45E-11NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922052810rs10757267GCrs10757267225706178.74E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922053687rs10965219AGrs10965219224280428.30E-07NANANA833 Japanese ancestry cases; 686 Japanese ancestry controlsJapanese(1519)ALL(1519)ASN(1519)ALL(1519)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNANAACDKN2B-AS1
922053687rs10965219AGrs10965219225706171.23E-08NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922053709rs7027048AGrs7027048225706171.30E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922054040rs7030641CTrs7030641224197381.88E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTCDKN2B-AS1
922054040rs7030641CTrs7030641225706175.09E-11NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922055048rs2383204AGrs2383204225706171.17E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922056213rs7039467AGrs7039467224197383.32E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tACDKN2B-AS1
922056295rs7853090TCrs7853090224197382.37E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCCDKN2B-AS1
922056359rs7866783AGrs7866783224197381.88E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGCDKN2B-AS1
922056359rs7866783AGrs7866783225706175.83E-11NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922056499rs10120688GArs10120688225706171.42E-13NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922059905rs10757268TCrs10757268224197382.44E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCCDKN2B-AS1
922060136rs2095144AGrs2095144224197382.45E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCCDKN2B-AS1
922060935rs2383205AGrs2383205224197382.45E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGCDKN2B-AS1
922060935rs2383205AGrs2383205225706177.52E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922061562rs2184061CArs2184061225706171.35E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922061614rs1537378AGrs1537378224197382.49E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCCDKN2B-AS1
922061614rs1537378AGrs1537378225706171.35E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922064391rs8181050GArs8181050224197382.51E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tACDKN2B-AS1
922064391rs8181050GArs8181050225706171.42E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922064465rs8181047AGrs8181047224197382.51E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGCDKN2B-AS1
922064465rs8181047AGrs8181047224280426.50E-09NANANA833 Japanese ancestry cases; 686 Japanese ancestry controlsJapanese(1519)ALL(1519)ASN(1519)ALL(1519)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNANAGCDKN2B-AS1
922064465rs8181047AGrs8181047225706179.16E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922065002rs10811647CGrs10811647225706176.07E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922065657rs1333039GCrs1333039224197381.44E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCCDKN2B-AS1
922065657rs1333039GCrs1333039225706171.35E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922066363rs4977755TArs4977755224197382.32E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTCDKN2B-AS1
922066363rs4977755TArs4977755225706174.19E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922067004rs10965223GArs10965223224197381.39E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tACDKN2B-AS1
922067276rs10965224TArs10965224224197381.40E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTCDKN2B-AS1
922067276rs10965224TArs10965224225706171.35E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922067542rs10811648CTrs10811648224197381.41E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCCDKN2B-AS1
922067542rs10811648CTrs10811648225706174.04E-11NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922067554rs10811649CTrs10811649224197381.82E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTCDKN2B-AS1
922067554rs10811649CTrs10811649225706172.68E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922067593rs10811650AGrs10811650225706176.07E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922067830rs10811651GArs10811651224197381.42E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tACDKN2B-AS1
922067830rs10811651GArs10811651225706171.32E-10NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922068652rs4977756GArs4977756224197381.44E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tACDKN2B-AS1
922068652rs4977756GArs4977756225706177.34E-16NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922072264rs10757269AGrs10757269225706171.80E-08NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922072301rs9632884GCrs9632884224280423.40E-04NANANA833 Japanese ancestry cases; 686 Japanese ancestry controlsJapanese(1519)ALL(1519)ASN(1519)ALL(1519)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNANACCDKN2B-AS1
922072301rs9632884GCrs9632884225706171.23E-08NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922072638rs9632885GArs9632885225706179.49E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922072719rs10757270AGrs10757270225706174.35E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922077085rs10811652ACrs10811652225706173.50E-08NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922077543rs1412832CTrs1412832225706172.36E-12NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922081397rs10116277GTrs10116277225706173.45E-11NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922083404rs1333040CTrs1333040225706174.88E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922088260rs10757272CTrs10757272224280429.20E-04NANANA833 Japanese ancestry cases; 686 Japanese ancestry controlsJapanese(1519)ALL(1519)ASN(1519)ALL(1519)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNANACCDKN2B-AS1
922098574rs4977574AGrs4977574224280423.50E-05NANANA833 Japanese ancestry cases; 686 Japanese ancestry controlsJapanese(1519)ALL(1519)ASN(1519)ALL(1519)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNANAACDKN2B-AS1
922098574rs4977574AGrs4977574225706174.33E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922098619rs2891168AGrs2891168224280424.80E-05NANANA833 Japanese ancestry cases; 686 Japanese ancestry controlsJapanese(1519)ALL(1519)ASN(1519)ALL(1519)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNANAACDKN2B-AS1
922103813rs1333042AGrs1333042224280424.40E-04NANANA833 Japanese ancestry cases; 686 Japanese ancestry controlsJapanese(1519)ALL(1519)ASN(1519)ALL(1519)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNANAACDKN2B-AS1
922115286rs944797TCrs944797225706175.94E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922115959rs2383207AGrs2383207225706171.20E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922116071rs1537375TCrs1537375225706175.75E-09NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
922125347rs1333048ACrs1333048224280421.40E-04NANANA833 Japanese ancestry cases; 686 Japanese ancestry controlsJapanese(1519)ALL(1519)ASN(1519)ALL(1519)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNANAANA
922125503rs1333049GCrs1333049224280428.30E-05NANANA833 Japanese ancestry cases; 686 Japanese ancestry controlsJapanese(1519)ALL(1519)ASN(1519)ALL(1519)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNANACNA
922985934rs12349792ATrs12349792224197384.46E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tANA
922987182rs1350996GArs1350996224197384.78E-04NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGNA
922990235rs17696405GArs17696405224197383.95E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGNA
935573942rs7389781TArs7389781226059215.23E-07NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tANA
976741416rs4237260GCrs4237260226059214.98E-07NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGNA
987597827rs9802671CArs9802671226059217.33E-04NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNTRK2
9107695848rs2472493GArs2472493208352386.70E-05NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
9112983819rs10816943AGrs10816943208352388.00E-05NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
1010144990rs10905663GTrs10905663226059216.41E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGNA
1010303947rs10795783ACrs10795783226059216.03E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tANA
1010874408rs4749995GArs4749995226059211.36E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tANA
1020638885rs7081455GTrs7081455196256181.00E-05Primary open-angle glaucomaNANA418 Japanese cases; 300 Japanese controlsJapanese(718)ALL(718)ASN(718)ALL(718)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTNA
1044671194rs11238892CTrs11238892226059212.48E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
1055000332rs17678511CTrs17678511226059211.42E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
1061336292rs11813512AGrs11813512224197382.96E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tANA
10110732731rs11596823AGrs11596823208352382.70E-05NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
10110739765rs10509885CTrs10509885208352382.70E-05NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
117652385rs4130354TArs4130354226059214.06E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tAPPFIBP2
1117008605rs11024102TCrs11024102229228755.00E-12NA1.22NA984 Singaporean Chinese cases; 943 Singaporean Chinese controls; 297 Han Chinese cases; 1,044 Han Chinese controls; 573 South Asian ancestry cases; 3,065 Singaporean Malaysian controls; 2,538 Singaporean Indian controls; 2,018 Vietnamese ancestry controls.South Asian(573)Singaporean Malaysian(3065)Han Chinese(1341)Singaporean Indian(2538)Vietnamese(2018)Singaporean Chinese(1927)ALL(11462)ASN(8351)SAN(3111)ALL(11462)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190
1117015557rs6486334TCrs6486334229228759.07E-08NANANA984 Singaporean Chinese cases; 943 Singaporean Chinese controls; 297 Han Chinese cases; 1,044 Han Chinese controls; 573 South Asian ancestry cases; 3,065 Singaporean Malaysiansian controls; 2,538 Singaporean Indian controls; 2,018 Vietnamese ancestry controls.South Asian(573)Singaporean Malaysian(3065)Han Chinese(1341)Singaporean Indian(2538)Vietnamese(2018)Singaporean Chinese(1927)ALL(11462)ASN(8351)SAN(3111)ALL(11462)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190
1120623042rs1443548TCrs1443548208352389.50E-06NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
1127804725rs11607128CArs11607128226059216.60E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
1127980881rs1949876TArs1949876226059214.62E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTNA
1195975925rs544656GTrs544656226059215.97E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTMAML2
11110696247rs5005886CArs5005886224197384.58E-04NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
11121092052rs745517CTrs745517224197385.37E-04NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTNA
11128156314rs12795702AGrs12795702224197382.56E-04NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tANA
1257321212rs7296999CTrs7296999226059211.63E-07NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCSDR9C7
1263673968rs1909327CTrs1909327208352387.40E-05NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
1266167085rs10878333AGrs10878333226059213.65E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGRPSAP52
1270440646rs1239904GTrs1239904224280423.00E-08NANANA833 Japanese ancestry cases; 686 Japanese ancestry controlsJapanese(1519)ALL(1519)ASN(1519)ALL(1519)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNANATNA
1271381548rs4492904CArs4492904226059211.83E-07NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
1283091836rs7961953GArs7961953196256187.00E-05Primary open-angle glaucomaNANA418 Japanese cases; 300 Japanese controlsJapanese(718)ALL(718)ASN(718)ALL(718)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGTMTC2
1293681302rs7486291TArs7486291208352382.50E-06NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
1396826213rs17675800CArs17675800226059218.36E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCHS6ST3
13101458632rs1041015AGrs1041015208352384.20E-05NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
1433658745rs912855CTrs912855208352384.20E-05NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
1433757906rs4982066AGrs4982066208352388.50E-05NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
1433829320rs2274511CTrs2274511208352386.70E-05NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
1457196255rs6573104ACrs6573104224197381.37E-04NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tANA
1460789176rs4901977CTrs4901977225706173.37E-08NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1460792103rs2350892AGrs2350892224197381.52E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGNA
1460794782rs1885095TCrs1885095224197382.82E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
1460796648rs2180833TCrs2180833224197381.37E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
1460798009rs6573307TGrs6573307224197386.49E-07NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGNA
1460806976rs6573308CTrs6573308224197381.15E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTNA
1460808002rs4436712GTrs4436712224197381.19E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTNA
1460847001rs1254276CTrs1254276224197382.25E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTNA
1460848224rs1313237ACrs1313237224197382.51E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
1460886150rs1272131TCrs1272131224197381.88E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
1460957279rs2093210CTrs2093210224197382.41E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
1460971137rs1018533TCrs1018533225706175.43E-08NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1460976537rs33912345CArs33912345224197382.74E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCSIX6
1460983087rs12436579CArs12436579225706171.42E-06NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1461000665rs7152532CTrs7152532225706172.62E-05NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1461003889rs4899012GCrs4899012224197383.04E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGNA
1461005625rs1010053AGrs1010053225706179.48E-08NANANA3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1461008596rs7159392TCrs7159392224197382.98E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTNA
1461013237rs2351174GTrs2351174224197383.43E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGNA
1461021891rs1955695AGrs1955695224197383.77E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tANA
1461025617rs4442732AGrs4442732224197383.79E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tANA
1461072875rs10483727TCrs10483727224197389.00E-08NA1.27[1.18-1.37] 1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomars10483727-TResearch Support, Non-U.S. Gov'tTNA
1461072875rs10483727TCrs10483727225706174.00E-11NA1.32[1.21-1.43]3,146 European ancestry cases; 3,487 European ancestry controlsEuropean(6633)ALL(6633)EUR(6633)ALL(6633)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomars10483727-AResearch Support, N.I.H., ExtramuralMeta-AnalysisResearch Support, Non-U.S. Gov't
1461091401rs34935520GArs34935520224197384.88E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGNA
1461095174rs35155027GCrs35155027224197384.97E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGNA
1461108825rs35320790CArs35320790224197386.59E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
1461124940rs10143202AGrs10143202226059212.15E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tANA
1461949051rs1886464GArs1886464224197381.08E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tAPRKCH
1461949933rs912619TCrs912619224197381.06E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTPRKCH
1461951101rs3783774CGrs3783774224197381.06E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGPRKCH
1461953406rs1957898TCrs1957898224197388.56E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTPRKCH
1461953839rs4902063CTrs4902063224197388.00E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCPRKCH
1461954272rs12886896CTrs12886896224197388.20E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCPRKCH
1461954594rs11622805GArs11622805224197387.40E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGPRKCH
1461954761rs35014123CArs35014123224197387.61E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCPRKCH
1461956958rs4902067CGrs4902067224197386.07E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCPRKCH
1461961410rs12897140GCrs12897140224197381.10E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGPRKCH
1461963561rs4902071CTrs4902071224197381.16E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTPRKCH
1461978571rs1088683CTrs1088683224197381.56E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tT,CPRKCH
1461984087rs1091680AGrs1091680224197381.94E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tAPRKCH
1461984684rs2252267AGrs2252267224197381.54E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTPRKCH
1461990633rs2253026GArs2253026224197388.74E-06NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCPRKCH
1461990861rs12883769CTrs12883769224197382.79E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTPRKCH
1461991812rs1088667CGrs1088667224197382.55E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGPRKCH
1461998747rs1091331CTrs1091331224197381.85E-05NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGPRKCH
1472735347rs9323567CTrs9323567226059214.17E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCRGS6
1474782515rs879823AGrs879823226059211.52E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTNA
1493685097rs17128941CTrs17128941226059215.52E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCUBR7
1571999067rs872476ATrs872476235368070.00013NANANA200 cases; 197 controlsNOPOP(397)ALL(397)NOPOP(397)ALL(397)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralTTHSD4
1574222202rs2165241TCrs2165241208352388.50E-08NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
1574225193rs8041685GArs8041685208352387.60E-06NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
1574235500rs2304719CTrs2304719208352384.00E-05NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
1579510909rs4779012CArs4779012208352388.00E-05NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
1594763672rs1378593TCrs1378593224197384.10E-04NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tANA
1599037854rs12595471CTrs12595471226059212.46E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCFAM169B
1618957762rs7205322GArs7205322208352382.00E-06NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
1683664226rs722939AGrs722939226059217.83E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTCDH13
1714420822rs2875006AGrs2875006208352384.50E-05NANANA1,263 Icelandic cases; 34,887 Icelandic controlsIcelandic(36150)ALL(36150)EUR(36150)ALL(36150)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.
1734163565rs4239252GArs4239252226059212.46E-05NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tATAF15
1742993855rs3760379AGrs3760379224197383.14E-04NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCGFAP
1825532723rs9963326AGrs9963326226059213.21E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tACDH2
1847134465rs11664741GTrs11664741226059212.13E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tTNA
2011242433rs4813974CTrs4813974224197381.41E-04NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
2044433017rs6514063CTrs6514063224197383.10E-04NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCDNTTIP1
2044506661rs17446462GArs17446462224197382.00E-04NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGZSWIM3
2045493264rs6066093TCrs6066093224197385.33E-04NANANA1,394 Japanese ancestry cases; 6,599 Japanese ancestry controlsJapanese(7993)ALL(7993)ASN(7993)ALL(7993)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tCNA
2144053466rs915848TCrs915848226059217.73E-04NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tNANA
2219558475rs5746779AGrs5746779226059215.88E-06NANANA387 European ancestry cases; 5,380 European ancestry controlsEuropean(5767)ALL(5767)EUR(5767)ALL(5767)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190glaucomaGlaucomaNAResearch Support, Non-U.S. Gov'tGNA
2219889825rs3788317GTrs3788317229228752.00E-07NA1.22NA984 Singaporean Chinese cases; 943 Singaporean Chinese controls; 297 Han Chinese cases; 1,044 Han Chinese controls; 573 South Asian ancestry cases; 3,065 Singaporean Malaysian controls; 2,538 Singaporean Indian controls; 2,018 Vietnamese ancestry controls.South Asian(573)Singaporean Malaysian(3065)Han Chinese(1341)Singaporean Indian(2538)Vietnamese(2018)Singaporean Chinese(1927)ALL(11462)ASN(8351)SAN(3111)ALL(11462)Glaucoma (primary open-angle)HPOID:0012108Primary open angle glaucomaDOID:1686glaucomaD005902Glaucoma, Open-AngleEFOID:0004190
Mapped by lexical matching(Total Items:0)
(Waiting for update.)
Mapped by homologous gene(Total Items:0)
(Waiting for update.)
Chemical(Total Drugs:6)
CUI ChemicalName ChemicalID CasRN DiseaseName DiseaseID DirectEvidence PubMedIDs
C0017612colchicineD00307864-86-8glaucoma, open-angleMESH:D005902therapeutic12446362
C0017612diclofenacD00400815307-86-5glaucoma, open-angleMESH:D005902therapeutic12446362
C0017612dipivefrinC01517352365-63-6glaucoma, open-angleMESH:D005902therapeutic6639507
C0017612mitomycinD0166851950/7/7glaucoma, open-angleMESH:D005902therapeutic7825687
C0017612pilocarpineD01086292-13-7glaucoma, open-angleMESH:D005902therapeutic18721251
C0017612timololD01399926839-75-8glaucoma, open-angleMESH:D005902therapeutic11116726
FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)
FDA labeling changes(Total Drugs:0)
(Waiting for update.)