All Snps(Total Genotypes:20) |
|---|
| snpId |
pubmedId |
geneId |
geneSymbol |
diseaseId |
sourceId |
sentence |
score |
Year |
geneSymbol_dbSNP |
CHROMOSOME |
POS |
REF |
ALT |
| rs10433310 | 22451332 | 3630 | INS | umls:C0520679 | BeFree | Childhood OSA is associated with higher plasma MIF, hsCRP, and fasting insulin levels that promote cardiometabolic risk, and the MIF gene SNP rs10433310 may account for some of the variance in such risk. | 0.000542884 | 2012 | MIF-AS1 | 22 | 23896636 | G | A |
| rs11126184 | 23155414 | 1902 | LPAR1 | umls:C0520679 | BeFree | Using a panel of 46,449 polymorphisms from roughly 2,100 candidate genes on a customized Illumina iSelect chip, we tested for association with the apnea hypopnea index (AHI) as well as moderate to severe OSA (AHI≥15) in 3,551 participants of the Cleveland Family Study and two cohorts participating in the Sleep Heart Health Study.Among 647 African-Americans, rs11126184 in the pleckstrin (PLEK) gene was associated with OSA while rs7030789 in the lysophosphatidic acid receptor 1 (LPAR1) gene was associated with AHI using a chip-wide significance threshold of p-value<2×10(-6). | 0.000271442 | 2012 | NA | 2 | 68425042 | C | A |
| rs11126184 | 23155414 | 5341 | PLEK | umls:C0520679 | BeFree | Using a panel of 46,449 polymorphisms from roughly 2,100 candidate genes on a customized Illumina iSelect chip, we tested for association with the apnea hypopnea index (AHI) as well as moderate to severe OSA (AHI≥15) in 3,551 participants of the Cleveland Family Study and two cohorts participating in the Sleep Heart Health Study.Among 647 African-Americans, rs11126184 in the pleckstrin (PLEK) gene was associated with OSA while rs7030789 in the lysophosphatidic acid receptor 1 (LPAR1) gene was associated with AHI using a chip-wide significance threshold of p-value<2×10(-6). | 0.000271442 | 2012 | NA | 2 | 68425042 | C | A |
| rs13170573 | 25474115 | 6444 | SGCD | umls:C0520679 | BeFree | The CC genotype of the delta-sarcoglycan gene polymorphism rs13170573 is associated with obstructive sleep apnea in the Chinese population. | 0.000271442 | 2014 | SGCD;LOC105377674 | 5 | 156327182 | C | G |
| rs1409986 | 23155414 | 5733 | PTGER3 | umls:C0520679 | BeFree | Among 2,904 individuals of European ancestry, rs1409986 in the prostaglandin E2 receptor (PTGER3) gene was significantly associated with OSA. | 0.000271442 | 2012 | PTGER3 | 1 | 70865815 | A | G |
| rs1800629 | 22043116 | 7124 | TNF | umls:C0520679 | BeFree | Only TNFA rs1800629 was significantly associated with OSA under an allele frequency model (3 studies, odds ratio [OR] = 1.82, 95% confidence interval [CI] 1.26-2.61). | 0.015449781 | 2011 | TNF | 6 | 31575254 | G | A |
| rs386602276 | 16258205 | 3358 | HTR2C | umls:C0520679 | BeFree | Genotypes and allele frequencies of 102T/C polymorphism of the HTR2A and 796G/C polymorphism of the HTR2C did not differ between controls and patients with OSA. | 0.005005506 | 2005 | NA | NA | NA | NA | NA |
| rs386602276 | 24065538 | 3356 | HTR2A | umls:C0520679 | BeFree | Association between the -1438G/A and T102C polymorphisms of 5-HT2A receptor gene and obstructive sleep apnea: a meta-analysis. | 0.007177041 | 2013 | NA | NA | NA | NA | NA |
| rs386602276 | 16258205 | 3356 | HTR2A | umls:C0520679 | BeFree | Genotypes and allele frequencies of 102T/C polymorphism of the HTR2A and 796G/C polymorphism of the HTR2C did not differ between controls and patients with OSA. | 0.007177041 | 2005 | NA | NA | NA | NA | NA |
| rs4673 | 21902598 | 1535 | CYBA | umls:C0520679 | BeFree | The frequencies of NADPH oxidase (NOX) polymorphisms in the p22phox subunit were similar between children with OSA and controls, except for rs6520785 and rs4673, the latter being significantly more frequent among the OSA children without deficits than with deficits (p<0.02). | 0.003181358 | 2012 | CYBA | 16 | 88646828 | A | G |
| rs4751440 | 20405330 | 594857 | NPS | umls:C0520679 | BeFree | We investigated the association of the non-synonymous polymorphism rs4751440 in the NPS precursor gene with OSAS and certain variables related to OSAS (daytime sleepiness, body mass index (BMI), insulin resistance, and blood pressure). | 0.000271442 | 2011 | NPS | 10 | 127552592 | G | A,C |
| rs5370 | 18580062 | 1906 | EDN1 | umls:C0520679 | BeFree | Endothelin-1 gene variant Lys198Asn and plasma endothelin level in obstructive sleep apnea. | 0.090639772 | 2009 | EDN1 | 6 | 12296022 | G | T |
| rs6313 | 16258205 | 3356 | HTR2A | umls:C0520679 | BeFree | Genotypes and allele frequencies of 102T/C polymorphism of the HTR2A and 796G/C polymorphism of the HTR2C did not differ between controls and patients with OSA. | 0.007177041 | 2005 | HTR2A | 13 | 46895805 | G | A |
| rs6313 | 24065538 | 3356 | HTR2A | umls:C0520679 | BeFree | Association between the -1438G/A and T102C polymorphisms of 5-HT2A receptor gene and obstructive sleep apnea: a meta-analysis. | 0.007177041 | 2013 | HTR2A | 13 | 46895805 | G | A |
| rs6313 | 16258205 | 3358 | HTR2C | umls:C0520679 | BeFree | Genotypes and allele frequencies of 102T/C polymorphism of the HTR2A and 796G/C polymorphism of the HTR2C did not differ between controls and patients with OSA. | 0.005005506 | 2005 | HTR2A | 13 | 46895805 | G | A |
| rs6520785 | 21902598 | 1535 | CYBA | umls:C0520679 | BeFree | The frequencies of NADPH oxidase (NOX) polymorphisms in the p22phox subunit were similar between children with OSA and controls, except for rs6520785 and rs4673, the latter being significantly more frequent among the OSA children without deficits than with deficits (p<0.02). | 0.003181358 | 2012 | CYBB | X | 37785172 | C | G |
| rs6888451 | 25660813 | 133522 | PPARGC1B | umls:C0520679 | BeFree | In peroxisome proliferator-activated receptor gamma, coactivator 1 beta (PPARGC1B), rs6888451 was associated with several markers of obstructive sleep apnea. | 0.000271442 | 2014 | PPARGC1B | 5 | 149744371 | C | G,T |
| rs7030789 | 23155414 | 5341 | PLEK | umls:C0520679 | BeFree | Using a panel of 46,449 polymorphisms from roughly 2,100 candidate genes on a customized Illumina iSelect chip, we tested for association with the apnea hypopnea index (AHI) as well as moderate to severe OSA (AHI≥15) in 3,551 participants of the Cleveland Family Study and two cohorts participating in the Sleep Heart Health Study.Among 647 African-Americans, rs11126184 in the pleckstrin (PLEK) gene was associated with OSA while rs7030789 in the lysophosphatidic acid receptor 1 (LPAR1) gene was associated with AHI using a chip-wide significance threshold of p-value<2×10(-6). | 0.000271442 | 2012 | LPAR1 | 9 | 110973232 | A | G |
| rs7030789 | 23155414 | 1902 | LPAR1 | umls:C0520679 | BeFree | Using a panel of 46,449 polymorphisms from roughly 2,100 candidate genes on a customized Illumina iSelect chip, we tested for association with the apnea hypopnea index (AHI) as well as moderate to severe OSA (AHI≥15) in 3,551 participants of the Cleveland Family Study and two cohorts participating in the Sleep Heart Health Study.Among 647 African-Americans, rs11126184 in the pleckstrin (PLEK) gene was associated with OSA while rs7030789 in the lysophosphatidic acid receptor 1 (LPAR1) gene was associated with AHI using a chip-wide significance threshold of p-value<2×10(-6). | 0.000271442 | 2012 | LPAR1 | 9 | 110973232 | A | G |
| rs9526240 | 20538960 | 3356 | HTR2A | umls:C0520679 | BeFree | In African Americans, rs9526240 within serotonin receptor 2a (HTR2A: odds ratio = 2.1; 95% confidence interval, 1.5-2.9; P = 0.00005233) was associated with OSA. | 0.007177041 | 2010 | HTR2A | 13 | 46857336 | G | A |
