PedAM

Pediatric Disease Annotations & Medicines


	obstructive hydrocephalus

Disease ID	1760
Disease	obstructive hydrocephalus
Definition	An abnormal accumulation of cerebrospinal fluid within the ventricles of the brain that occurs as a consequence of an obstruction at any location within the ventricular system that prevents cerebrospinal fluid flowing into the subarachnoid space.
Synonym	hydrocephalus, noncommunicating hydrocephalus, obstructive non-communicating hydrocephalus obstructiv hydrocephalus obstructive hydrocephalus (disorder)
DOID	DOID:14159
ICD10	ICD10CM:G91.1
UMLS	C0549423
SNOMED-CT	SNOMEDCT_US_2016_09_01:230746009
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:31) C0151740 \| increased intracranial pressure \| 5 C0151740 \| intracranial hypertension \| 4 C0025289 \| meningitis \| 3 C0020538 \| hypertension \| 2 C0025309 \| meningoencephalitis \| 1 C0152013 \| lung adenocarcinoma \| 1 C0010276 \| craniopharyngiomas \| 1 C0010276 \| craniopharyngioma \| 1 C0040558 \| toxoplasmosis \| 1 C0151740 \| elevated intracranial pressure \| 1 C0334583 \| pilocytic astrocytoma \| 1 C0879615 \| stromal tumor \| 1 C0041318 \| tuberculous meningitis \| 1 C0917996 \| cerebral aneurysm \| 1 C0078981 \| arachnoid cyst \| 1 C0001418 \| adenocarcinoma \| 1 C0032285 \| pneumoniae \| 1 C0040053 \| thrombosis \| 1 C0085273 \| parvovirus b19 infection \| 1 C0012569 \| diplopia \| 1 C0238198 \| gastrointestinal stromal tumor \| 1 C0037198 \| sinus thrombosis \| 1 C0026934 \| mycoplasma \| 1 C1332900 \| cerebellar hemangioblastoma \| 1 C0004114 \| astrocytoma \| 1 C0020255 \| hydrocephalus \| 1 C0085315 \| cns toxoplasmosis \| 1 C0032302 \| mycoplasma pneumonia \| 1 C0206660 \| germinoma \| 1 C0206734 \| hemangioblastoma \| 1 C0151740 \| raised intracranial pressure \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:81) 10301 \| DLEU1 \| DISEASES 2288 \| FKBP4 \| DISEASES 7249 \| TSC2 \| DISEASES 5327 \| PLAT \| DISEASES 2026 \| ENO2 \| DISEASES 4488 \| MSX2 \| DISEASES 10804 \| GJB6 \| DISEASES 2670 \| GFAP \| DISEASES 6538 \| SLC6A11 \| DISEASES 3021 \| H3F3B \| DISEASES 4440 \| MSI1 \| DISEASES 10241 \| CALCOCO2 \| DISEASES 23314 \| SATB2 \| DISEASES 4659 \| PPP1R12A \| DISEASES 4591 \| TRIM37 \| DISEASES 9368 \| SLC9A3R1 \| DISEASES 6855 \| SYP \| DISEASES 90 \| ACVR1 \| DISEASES 10000 \| AKT3 \| DISEASES 390 \| RND3 \| DISEASES 2121 \| EVC \| DISEASES 7157 \| TP53 \| DISEASES 285362 \| SUMF1 \| DISEASES 5921 \| RASA1 \| DISEASES 4715 \| NDUFB9 \| DISEASES 23657 \| SLC7A11 \| DISEASES 7082 \| TJP1 \| DISEASES 2895 \| GRID2 \| DISEASES 4838 \| NODAL \| DISEASES 7547 \| ZIC3 \| DISEASES 2177 \| FANCD2 \| DISEASES 2176 \| FANCC \| DISEASES 1278 \| COL1A2 \| DISEASES 5617 \| PRL \| DISEASES 5340 \| PLG \| DISEASES 358 \| AQP1 \| DISEASES 8557 \| TCAP \| DISEASES 2302 \| FOXJ1 \| DISEASES 1641 \| DCX \| DISEASES 5873 \| RAB27A \| DISEASES 6540 \| SLC6A13 \| DISEASES 113675 \| SDSL \| DISEASES 4771 \| NF2 \| DISEASES 4763 \| NF1 \| DISEASES 4478 \| MSN \| DISEASES 2475 \| MTOR \| DISEASES 3020 \| H3F3A \| DISEASES 3664 \| IRF6 \| DISEASES 8676 \| STX11 \| DISEASES 7062 \| TCHH \| DISEASES 4803 \| NGF \| DISEASES 51684 \| SUFU \| DISEASES 6005 \| RHAG \| DISEASES 5728 \| PTEN \| DISEASES 1025 \| CDK9 \| DISEASES 5081 \| PAX7 \| DISEASES 1325 \| CORT \| DISEASES 317762 \| CCDC85C \| DISEASES 427 \| ASAH1 \| DISEASES 26278 \| SACS \| DISEASES 4487 \| MSX1 \| DISEASES 361 \| AQP4 \| DISEASES 9901 \| SRGAP3 \| DISEASES 5077 \| PAX3 \| DISEASES 9244 \| CRLF1 \| DISEASES 5091 \| PC \| DISEASES 174 \| AFP \| DISEASES 3166 \| HMX1 \| DISEASES 501 \| ALDH7A1 \| DISEASES 9048 \| ARTN \| DISEASES 1875 \| E2F5 \| DISEASES 6559 \| SLC12A3 \| DISEASES 139728 \| PNCK \| DISEASES 284252 \| KCTD1 \| DISEASES 2668 \| GDNF \| DISEASES 2263 \| FGFR2 \| DISEASES 4140 \| MARK3 \| DISEASES 627 \| BDNF \| DISEASES 83695 \| RHNO1 \| DISEASES 6642 \| SNX1 \| DISEASES 102723508 \| KANTR \| DISEASES
Locus	(Waiting for update.)

Disease ID	1760
Disease	obstructive hydrocephalus
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:36) HP:0002516 \| Intracranial pressure elevation \| 9 HP:0002664 \| Neoplasia \| 6 HP:0002315 \| Headaches \| 4 HP:0001287 \| Meningitis \| 3 HP:0002410 \| Aqueductal stenosis \| 3 HP:0011695 \| Cerebellar hemorrhage \| 2 HP:0002119 \| Ventricular dilatation \| 2 HP:0000822 \| Hypertension \| 2 HP:0000969 \| Dropsy \| 2 HP:0012683 \| Pineal cyst \| 2 HP:0100702 \| Arachnoid cyst \| 1 HP:0000651 \| Diplopia \| 1 HP:0004936 \| Blood clot in vein \| 1 HP:0004490 \| Hyperostosis of calvarial bones \| 1 HP:0002615 \| Low blood pressure \| 1 HP:0030062 \| Craniopharyngioma \| 1 HP:0010797 \| Hemangioblastoma \| 1 HP:0005305 \| Cerebral vein thrombosis \| 1 HP:0001270 \| Motor retardation \| 1 HP:0006880 \| Hemangioblastoma, sporadic cerebellar \| 1 HP:0000238 \| Nonsyndromal hydrocephalus \| 1 HP:0002344 \| Progressive neurologic deterioration \| 1 HP:0009592 \| Astrocytoma \| 1 HP:0002018 \| Nausea \| 1 HP:0030078 \| Lung adenocarcinoma \| 1 HP:0001263 \| Developmental retardation \| 1 HP:0030746 \| Intraventricular hemorrhage \| 1 HP:0001289 \| Confusion \| 1 HP:0001298 \| Encephalopathy \| 1 HP:0030692 \| Brain tumor \| 1 HP:0100723 \| Gastrointestinal stroma tumor \| 1 HP:0012062 \| Bone cysts \| 1 HP:0012063 \| Aneurysmal bone cyst \| 1 HP:0002902 \| Hyponatremia \| 1 HP:0009733 \| Glioma \| 1 HP:0004944 \| Cerebral artery aneurysm \| 1

Disease ID	1760
Disease	obstructive hydrocephalus
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:3) C0151740 \| increased intracranial pressure \| 5 C0151740 \| intracranial hypertension \| 4 C0151740 \| raised intracranial pressure \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:0)
(Waiting for update.)

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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