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Pediatric Disease Annotations & Medicines



   non-langerhans-cell histiocytosis
  

Disease ID 1896
Disease non-langerhans-cell histiocytosis
Definition
Group of disorders which feature accumulations of active HISTIOCYTES and LYMPHOCYTES, but where the histiocytes are not LANGERHANS CELLS. The group includes HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; SINUS HISTIOCYTOSIS; xanthogranuloma; reticulohistiocytoma; JUVENILE XANTHOGRANULOMA; xanthoma disseminatum; as well as the lipid storage diseases (SEA-BLUE HISTIOCYTE SYNDROME; and NIEMANN-PICK DISEASES).
Synonym
cell histiocytosis non langerhans
histiocytosis, non langerhans cell
histiocytosis, non-langerhans-cell
histiocytosis, non-langerhans-cell [disease/finding]
non-langerhans cell histiocytosis
Orphanet
DOID
UMLS
C0019624
MeSH
Curated Gene
Entrez_id | Symbol | Resource(Total Genes:4)
NPC2  |  10577  |  UniProtKB-KW;GHR
SMPD1  |  6609  |  UniProtKB-KW;GHR
NPC1  |  4864  |  UniProtKB-KW;GHR
BRAF  |  673  |  GHR
Inferring Gene(Waiting for update.)
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:139)
4074  |  M6PR  |  DISEASES
6362  |  CCL18  |  DISEASES
5009  |  OTC  |  DISEASES
4504  |  MT3  |  DISEASES
50487  |  PLA2G3  |  DISEASES
410  |  ARSA  |  DISEASES
5816  |  PVALB  |  DISEASES
54  |  ACP5  |  DISEASES
23659  |  PLA2G15  |  DISEASES
8767  |  RIPK2  |  DISEASES
4669  |  NAGLU  |  DISEASES
5564  |  PRKAB1  |  DISEASES
7942  |  TFEB  |  DISEASES
335  |  APOA1  |  DISEASES
9525  |  VPS4B  |  DISEASES
968  |  CD68  |  DISEASES
348  |  APOE  |  DISEASES
684  |  BST2  |  DISEASES
5565  |  PRKAB2  |  DISEASES
27183  |  VPS4A  |  DISEASES
23640  |  HSPBP1  |  DISEASES
5156  |  PDGFRA  |  DISEASES
90070  |  LACRT  |  DISEASES
6610  |  SMPD2  |  DISEASES
23205  |  ACSBG1  |  DISEASES
3557  |  IL1RN  |  DISEASES
4069  |  LYZ  |  DISEASES
6505  |  SLC1A1  |  DISEASES
8647  |  ABCB11  |  DISEASES
5007  |  OSBP  |  DISEASES
5290  |  PIK3CA  |  DISEASES
3931  |  LCAT  |  DISEASES
60482  |  SLC5A7  |  DISEASES
3383  |  ICAM1  |  DISEASES
950  |  SCARB2  |  DISEASES
411  |  ARSB  |  DISEASES
7879  |  RAB7A  |  DISEASES
29999  |  FSCN3  |  DISEASES
3073  |  HEXA  |  DISEASES
4864  |  NPC1  |  DISEASES
285362  |  SUMF1  |  DISEASES
91937  |  TIMD4  |  DISEASES
2893  |  GRIA4  |  DISEASES
23643  |  LY96  |  DISEASES
351  |  APP  |  DISEASES
5018  |  OXA1L  |  DISEASES
3156  |  HMGCR  |  DISEASES
673  |  BRAF  |  DISEASES
909  |  CD1A  |  DISEASES
29881  |  NPC1L1  |  DISEASES
3060  |  HCRT  |  DISEASES
134429  |  STARD4  |  DISEASES
84889  |  SLC7A3  |  DISEASES
2350  |  FOLR2  |  DISEASES
5267  |  SERPINA4  |  DISEASES
4665  |  NAB2  |  DISEASES
5604  |  MAP2K1  |  DISEASES
3308  |  HSPA4  |  DISEASES
2548  |  GAA  |  DISEASES
2720  |  GLB1  |  DISEASES
3265  |  HRAS  |  DISEASES
947  |  CD34  |  DISEASES
7368  |  UGT8  |  DISEASES
23166  |  STAB1  |  DISEASES
2629  |  GBA  |  DISEASES
4018  |  LPA  |  DISEASES
284359  |  IZUMO1  |  DISEASES
5271  |  SERPINB8  |  DISEASES
10227  |  MFSD10  |  DISEASES
256933  |  NPB  |  DISEASES
3916  |  LAMP1  |  DISEASES
3988  |  LIPA  |  DISEASES
3141  |  HLCS  |  DISEASES
23583  |  SMUG1  |  DISEASES
857  |  CAV1  |  DISEASES
6609  |  SMPD1  |  DISEASES
5781  |  PTPN11  |  DISEASES
2583  |  B4GALNT1  |  DISEASES
1508  |  CTSB  |  DISEASES
57515  |  SERINC1  |  DISEASES
9514  |  GAL3ST1  |  DISEASES
3638  |  INSIG1  |  DISEASES
26762  |  HAVCR1  |  DISEASES
347  |  APOD  |  DISEASES
5265  |  SERPINA1  |  DISEASES
6720  |  SREBF1  |  DISEASES
10507  |  SEMA4D  |  DISEASES
2760  |  GM2A  |  DISEASES
64919  |  BCL11B  |  DISEASES
257194  |  NEGR1  |  DISEASES
4763  |  NF1  |  DISEASES
404552  |  SCGB1D4  |  DISEASES
2526  |  FUT4  |  DISEASES
51454  |  GULP1  |  DISEASES
9332  |  CD163  |  DISEASES
5294  |  PIK3CG  |  DISEASES
6832  |  SUPV3L1  |  DISEASES
6721  |  SREBF2  |  DISEASES
1118  |  CHIT1  |  DISEASES
5788  |  PTPRC  |  DISEASES
5321  |  PLA2G4A  |  DISEASES
6646  |  SOAT1  |  DISEASES
910  |  CD1B  |  DISEASES
911  |  CD1C  |  DISEASES
10924  |  SMPDL3A  |  DISEASES
6280  |  S100A9  |  DISEASES
5710  |  PSMD4  |  DISEASES
1520  |  CTSS  |  DISEASES
4893  |  NRAS  |  DISEASES
5309  |  PITX3  |  DISEASES
89885  |  FATE1  |  DISEASES
5236  |  PGM1  |  DISEASES
27069  |  GHITM  |  DISEASES
5476  |  CTSA  |  DISEASES
7357  |  UGCG  |  DISEASES
367  |  AR  |  DISEASES
19  |  ABCA1  |  DISEASES
369  |  ARAF  |  DISEASES
2665  |  GDI2  |  DISEASES
427  |  ASAH1  |  DISEASES
6624  |  FSCN1  |  DISEASES
12  |  SERPINA3  |  DISEASES
1267  |  CNP  |  DISEASES
5660  |  PSAP  |  DISEASES
4668  |  NAGA  |  DISEASES
5609  |  MAP2K7  |  DISEASES
50489  |  CD207  |  DISEASES
9842  |  PLEKHM1  |  DISEASES
7124  |  TNF  |  DISEASES
5229  |  PGGT1B  |  DISEASES
1020  |  CDK5  |  DISEASES
9367  |  RAB9A  |  DISEASES
27  |  ABL2  |  DISEASES
84000  |  TMPRSS13  |  DISEASES
53373  |  TPCN1  |  DISEASES
10577  |  NPC2  |  DISEASES
2108  |  ETFA  |  DISEASES
348120  |  LINC01193  |  DISEASES
4555  |  MT-TD  |  DISEASES
Locus(Waiting for update.)
Disease ID 1896
Disease non-langerhans-cell histiocytosis
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype(Waiting for update.)
Disease ID 1896
Disease non-langerhans-cell histiocytosis
Manually Symptom(Waiting for update.)
Text Mined Symptom(Waiting for update.)
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:0)
(Waiting for update.)
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)
Mapped by lexical matching(Total Items:0)
(Waiting for update.)
Mapped by homologous gene(Total Items:0)
(Waiting for update.)
Chemical(Total Drugs:0)
(Waiting for update.)
FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)
FDA labeling changes(Total Drugs:0)
(Waiting for update.)