PedAM

Pediatric Disease Annotations & Medicines


	neurotic disorder

Disease ID	1316
Disease	neurotic disorder
Definition	Disorders in which the symptoms are distressing to the individual and recognized by him or her as being unacceptable. Social relationships may be greatly affected but usually remain within acceptable limits. The disturbance is relatively enduring or recurrent without treatment.
Synonym	[x] neurosis nos [x]neurosis nos [x]neurotic disorder, unspecified [x]neurotic disorder, unspecified (disorder) disorder, neurotic disorders, neurotic neuroses neurosis neurosis (disorder) neurosis, nos neurotic dis neurotic disorder (disorder) neurotic disorder nos neurotic disorder nos (disorder) neurotic disorders neurotic disorders [disease/finding] nonpsychotic mental disorder nonpsychotic mental disorder, nos psychoneuroses psychoneurosis psychoneurosis nos
DOID	DOID:4964
UMLS	C0027932
MeSH	D009497
SNOMED-CT	SNOMEDCT_US_2016_09_01:111475002
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:5) C0851578 \| sleep disorders \| 1 C0013473 \| eating disorder \| 1 C0003873 \| rheumatoid arthritis \| 1 C0013473 \| eating disorders \| 1 C0036341 \| schizophrenia \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:6) 91947 \| ARRDC4 \| infer 10082 \| GPC6 \| infer 161357 \| MDGA2 \| infer 154215 \| NKAIN2 \| infer 30010 \| NXPH1 \| infer 5144 \| PDE4D \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:100) 608 \| TNFRSF17 \| DISEASES 4335 \| MNT \| DISEASES 27248 \| ERLEC1 \| DISEASES 10005 \| ACOT8 \| DISEASES 3191 \| HNRNPL \| DISEASES 4353 \| MPO \| DISEASES 9450 \| LY86 \| DISEASES 374291 \| NDUFS7 \| DISEASES 8600 \| TNFSF11 \| DISEASES 56269 \| IRGC \| DISEASES 7166 \| TPH1 \| DISEASES 3630 \| INS \| DISEASES 27429 \| HTRA2 \| DISEASES 3357 \| HTR2B \| DISEASES 3569 \| IL6 \| DISEASES 23495 \| TNFRSF13B \| DISEASES 2033 \| EP300 \| DISEASES 3553 \| IL1B \| DISEASES 7301 \| TYRO3 \| DISEASES 2743 \| GLRB \| DISEASES 5443 \| POMC \| DISEASES 55749 \| CCAR1 \| DISEASES 5286 \| PIK3C2A \| DISEASES 5226 \| PGD \| DISEASES 55840 \| EAF2 \| DISEASES 2559 \| GABRA6 \| DISEASES 3358 \| HTR2C \| DISEASES 23643 \| LY96 \| DISEASES 201163 \| FLCN \| DISEASES 245972 \| ATP6V0D2 \| DISEASES 6781 \| STC1 \| DISEASES 1476 \| CSTB \| DISEASES 160622 \| GRASP \| DISEASES 4041 \| LRP5 \| DISEASES 256471 \| MFSD8 \| DISEASES 23588 \| KLHDC2 \| DISEASES 10206 \| TRIM13 \| DISEASES 219793 \| TBATA \| DISEASES 6632 \| SNRPD1 \| DISEASES 1281 \| COL3A1 \| DISEASES 8557 \| TCAP \| DISEASES 64236 \| PDLIM2 \| DISEASES 2688 \| GH1 \| DISEASES 3350 \| HTR1A \| DISEASES 5551 \| PRF1 \| DISEASES 6863 \| TAC1 \| DISEASES 23212 \| RRS1 \| DISEASES 5034 \| P4HB \| DISEASES 8784 \| TNFRSF18 \| DISEASES 29110 \| TBK1 \| DISEASES 10732 \| TCFL5 \| DISEASES 1103 \| CHAT \| DISEASES 4842 \| NOS1 \| DISEASES 25818 \| KLK5 \| DISEASES 3363 \| HTR7 \| DISEASES 4128 \| MAOA \| DISEASES 80320 \| SP6 \| DISEASES 4929 \| NR4A2 \| DISEASES 2879 \| GPX4 \| DISEASES 137902 \| PXDNL \| DISEASES 23224 \| SYNE2 \| DISEASES 26136 \| TES \| DISEASES 165679 \| SPTSSB \| DISEASES 79947 \| DHDDS \| DISEASES 11169 \| WDHD1 \| DISEASES 4860 \| PNP \| DISEASES 56259 \| CTNNBL1 \| DISEASES 8564 \| KMO \| DISEASES 284486 \| THEM5 \| DISEASES 4803 \| NGF \| DISEASES 2316 \| FLNA \| DISEASES 5236 \| PGM1 \| DISEASES 27022 \| FOXD3 \| DISEASES 81030 \| ZBP1 \| DISEASES 26190 \| FBXW2 \| DISEASES 2048 \| EPHB2 \| DISEASES 10673 \| TNFSF13B \| DISEASES 114798 \| SLITRK1 \| DISEASES 116085 \| SLC22A12 \| DISEASES 3356 \| HTR2A \| DISEASES 2098 \| ESD \| DISEASES 2625 \| GATA3 \| DISEASES 3045 \| HBD \| DISEASES 4155 \| MBP \| DISEASES 55576 \| STAB2 \| DISEASES 643418 \| LIPN \| DISEASES 8995 \| TNFSF18 \| DISEASES 1363 \| CPE \| DISEASES 55636 \| CHD7 \| DISEASES 7124 \| TNF \| DISEASES 2741 \| GLRA1 \| DISEASES 3586 \| IL10 \| DISEASES 627 \| BDNF \| DISEASES 26298 \| EHF \| DISEASES 6999 \| TDO2 \| DISEASES 5125 \| PCSK5 \| DISEASES 8972 \| MGAM \| DISEASES 820 \| CAMP \| DISEASES 104355217 \| ERICD \| DISEASES 102723508 \| KANTR \| DISEASES
Locus	(Waiting for update.)

Disease ID	1316
Disease	neurotic disorder
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:2) HP:0100753 \| Schizophrenia \| 1 HP:0001370 \| Rheumatoid arthritis \| 1

Disease ID	1316
Disease	neurotic disorder
Manually Symptom	(Waiting for update.)
Text Mined Symptom	(Waiting for update.)

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:7)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs12883384	18762592	161357	MDGA2	umls:C0027932	GAD	[The small effect sizes may limit the prognostic, diagnostic, and therapeutic use of SNP markers such as those in MAMDC1. However, the present study demonstrates the potential of a GWAS to discover potentially important pathogenic pathways for which clinic]	0.002367032	2008	MDGA2	14	46934481	A	C
rs2349775	18762592	30010	NXPH1	umls:C0027932	GAD	[The small effect sizes may limit the prognostic, diagnostic, and therapeutic use of SNP markers such as those in MAMDC1. However, the present study demonstrates the potential of a GWAS to discover potentially important pathogenic pathways for which clinic]	0.002367032	2008	NXPH1	7	8678450	G	A
rs2705293	18762592	401478	FLJ45872	umls:C0027932	GAD	[The small effect sizes may limit the prognostic, diagnostic, and therapeutic use of SNP markers such as those in MAMDC1. However, the present study demonstrates the potential of a GWAS to discover potentially important pathogenic pathways for which clinic]	0.002367032	2008	FLJ45872	8	137906702	C	T
rs4965121	20634892	91947	ARRDC4	umls:C0027932	GAD	[A genome-wide association study of neuroticism in a population-based sample.]	0.002367032	2010	NA	15	97975562	C	G
rs702543	17667963	5144	PDE4D	umls:C0027932	GAD	[A whole genome association study of neuroticism using DNA pooling.]	0.002367032	2008	PDE4D	5	59546948	C	T
rs9491140	20634892	154215	NKAIN2	umls:C0027932	GAD	[A genome-wide association study of neuroticism in a population-based sample.]	0.002367032	2010	NKAIN2	6	124370091	C	T
rs9561329	20634892	10082	GPC6	umls:C0027932	GAD	[A genome-wide association study of neuroticism in a population-based sample.]	0.002367032	2010	GPC6	13	93358916	A	G

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:57)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
1	34895009	rs17385253	T	C	rs17385253	17667963	3.30E-05	NA	NA	NA	1,038 cases; 1,016 controls	NOPOP(2054)	ALL(2054)	NOPOP(2054)	ALL(2054)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
1	58556598	rs873989	T	C	rs873989	17667963	1.30E-04	NA	NA	NA	1,038 cases; 1,016 controls	NOPOP(2054)	ALL(2054)	NOPOP(2054)	ALL(2054)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
1	164970360	rs6702388	T	C	rs6702388	23229837	8.49E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
1	182984597	rs10797812	G	A	rs10797812	17667963	2.40E-04	NA	NA	NA	1,038 cases; 1,016 controls	NOPOP(2054)	ALL(2054)	NOPOP(2054)	ALL(2054)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
1	231314221	rs9431663	A	G	rs9431663	17667963	1.20E-04	NA	NA	NA	1,038 cases; 1,016 controls	NOPOP(2054)	ALL(2054)	NOPOP(2054)	ALL(2054)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
2	67279960	rs7594674	G	A	rs7594674	17667963	6.50E-04	NA	NA	NA	1,038 cases; 1,016 controls	NOPOP(2054)	ALL(2054)	NOPOP(2054)	ALL(2054)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
2	102029646	rs12620464	T	C	rs12620464	23229837	4.09E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
2	148279693	rs6757820	T	C	rs6757820	23229837	1.51E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
2	152691829	rs2344734	C	G	rs2344734	23229837	3.61E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
2	163137983	rs10930046	T	C	rs10930046	23229837	4.68E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
3	64108853	rs985280	C	G	rs985280	23229837	2.61E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
3	69521568	rs9834457	T	C	rs9834457	23229837	6.10E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
4	18966569	rs2123315	T	C	rs2123315	17667963	4.30E-04	NA	NA	NA	1,038 cases; 1,016 controls	NOPOP(2054)	ALL(2054)	NOPOP(2054)	ALL(2054)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
4	142095763	rs7666238	A	G	rs7666238	17667963	9.00E-04	NA	NA	NA	1,038 cases; 1,016 controls	NOPOP(2054)	ALL(2054)	NOPOP(2054)	ALL(2054)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
5	3213546	rs6894463	G	A	rs6894463	23229837	4.81E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
5	58842774	rs702543	C	T	rs702543	17667963	2.00E-06		1.27	[1.15-1.40]	1,038 cases; 1,016 controls	NOPOP(2054)	ALL(2054)	NOPOP(2054)	ALL(2054)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
5	58941676	rs298024	C	A	rs298024	23229837	8.02E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
6	7556544	rs12198780	C	G	rs12198780	23229837	6.53E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
6	96089153	rs4342432	G	A	rs4342432	23229837	2.96E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
6	96112861	rs4510687	T	C	rs4510687	23229837	2.49E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
6	124691237	rs9491140	C	T	rs9491140	20634892	3.00E-07	main effect	0.91	[0.56-1.26] unit decrease	2,235 Caucasians	Caucasian(2235)	ALL(2235)	EUR(2235)	ALL(2235)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
7	8718080	rs2349775	G	A	rs2349775	18762592	7.00E-06		NA	NA	1,227 individuals	NOPOP(1227)	ALL(1227)	NOPOP(1227)	ALL(1227)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
7	136956607	rs322239	C	A	rs322239	17667963	4.80E-06	NA	NA	NA	1,038 cases; 1,016 controls	NOPOP(2054)	ALL(2054)	NOPOP(2054)	ALL(2054)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
8	3177911	rs4875610	C	A	rs4875610	17667963	4.10E-04	NA	NA	NA	1,038 cases; 1,016 controls	NOPOP(2054)	ALL(2054)	NOPOP(2054)	ALL(2054)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
8	8576642	rs9329165	A	G	rs9329165	17667963	3.00E-05	NA	NA	NA	1,038 cases; 1,016 controls	NOPOP(2054)	ALL(2054)	NOPOP(2054)	ALL(2054)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
8	8577093	rs4841017	T	C	rs4841017	17667963	6.50E-06	NA	NA	NA	1,038 cases; 1,016 controls	NOPOP(2054)	ALL(2054)	NOPOP(2054)	ALL(2054)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
8	39584168	rs201997	C	G	rs201997	17667963	2.70E-04	NA	NA	NA	1,038 cases; 1,016 controls	NOPOP(2054)	ALL(2054)	NOPOP(2054)	ALL(2054)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
8	51522706	rs16915079	A	T	rs16915079	23229837	5.54E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
8	52693940	rs7818832	A	T	rs7818832	23229837	9.70E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
8	52792173	rs7013587	A	C	rs7013587	23229837	9.53E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
8	88379205	rs10504830	A	G	rs10504830	17667963	1.10E-04	NA	NA	NA	1,038 cases; 1,016 controls	NOPOP(2054)	ALL(2054)	NOPOP(2054)	ALL(2054)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
8	121855774	rs4871135	G	A	rs4871135	23229837	7.33E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
8	123663461	rs1608361	T	C	rs1608361	23229837	4.13E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
8	138918945	rs2705293	C	T	rs2705293	18762592	6.00E-06		NA	NA	1,227 individuals	NOPOP(1227)	ALL(1227)	NOPOP(1227)	ALL(1227)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
9	3206279	rs4740720	A	G	rs4740720	23229837	7.63E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
9	34868377	rs13290746	C	T	rs13290746	17667963	1.50E-04	NA	NA	NA	1,038 cases; 1,016 controls	NOPOP(2054)	ALL(2054)	NOPOP(2054)	ALL(2054)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
9	131984706	rs4836644	G	T	rs4836644	23229837	8.00E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
9	131984729	rs4837349	G	A,C	rs4837349	23229837	6.42E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
11	32208950	rs10835855	A	G	rs10835855	23229837	5.15E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
12	13937320	rs220549	T	C	rs220549	23229837	1.05E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
13	54066896	rs1927860	A	C	rs1927860	23229837	9.23E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
13	94011169	rs9561329	A	G	rs9561329	20634892	1.00E-07	age interaction	0.17	[0.11-0.23] unit decrease	2,235 Caucasians	Caucasian(2235)	ALL(2235)	EUR(2235)	ALL(2235)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
14	22158637	rs9323020	T	G	rs9323020	23229837	3.29E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
14	47403684	rs12883384	A	C	rs12883384	18762592	7.00E-07		NA	NA	1,227 individuals	NOPOP(1227)	ALL(1227)	NOPOP(1227)	ALL(1227)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
14	47862477	rs10483573	C	G	rs10483573	17667963	5.60E-05	NA	NA	NA	1,038 cases; 1,016 controls	NOPOP(2054)	ALL(2054)	NOPOP(2054)	ALL(2054)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
15	98518792	rs4965121	C	G	rs4965121	20634892	1.00E-06	main effect	0.84	[0.51-1.17] unit decrease	2,235 Caucasians	Caucasian(2235)	ALL(2235)	EUR(2235)	ALL(2235)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
16	26277419	rs9807002	T	C	rs9807002	23229837	3.05E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
17	9314141	rs8068962	T	C	rs8068962	23229837	3.32E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
17	35345145	rs17651665	G	A	rs17651665	23229837	8.43E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
17	35378121	rs2301685	G	A	rs2301685	23229837	4.94E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
17	48248906	rs1046329	C	G	rs1046329	23229837	1.37E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
18	41515845	rs8096705	T	C	rs8096705	23229837	9.30E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
18	53117304	rs1452788	A	G	rs1452788	17667963	9.30E-04	NA	NA	NA	1,038 cases; 1,016 controls	NOPOP(2054)	ALL(2054)	NOPOP(2054)	ALL(2054)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
18	53964140	rs9959800	T	A	rs9959800	17667963	1.70E-04	NA	NA	NA	1,038 cases; 1,016 controls	NOPOP(2054)	ALL(2054)	NOPOP(2054)	ALL(2054)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
19	2410484	rs4806846	G	A	rs4806846	23229837	8.00E-06	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
20	40436666	rs6065392	T	C	rs6065392	23229837	5.02E-05	NA	NA	NA	2,748 European ancestry cases	European(2748)	ALL(2748)	EUR(2748)	ALL(2748)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA
20	55029758	rs401897	T	C	rs401897	17667963	6.50E-04	NA	NA	NA	1,038 cases; 1,016 controls	NOPOP(2054)	ALL(2054)	NOPOP(2054)	ALL(2054)	Neuroticism	HPOID:0000563	HPOID:0000545	Keratoconus	Myopia	DOID:2030	DOID:3324	DOID:1307	anxiety disorder	mood disorder	dementia	D009497	Neurotic Disorders	NA

Mapped by lexical matching(Total Items:0)
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Mapped by homologous gene(Total Items:0)
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Chemical(Total Drugs:0)
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FDA approved drug and dosage information(Total Drugs:0)
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FDA labeling changes(Total Drugs:0)
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