PedAM
Pediatric Disease Annotations & Medicines
| neurocysticercosis | ||||
| Disease ID | 1295 |
|---|---|
| Disease | neurocysticercosis |
| Definition | Infection of the brain, spinal cord, or perimeningeal structures with the larval forms of the genus TAENIA (primarily T. solium in humans). Lesions formed by the organism are referred to as cysticerci. The infection may be subacute or chronic, and the severity of symptoms depends on the severity of the host immune response and the location and number of lesions. SEIZURES represent the most common clinical manifestation although focal neurologic deficits may occur. (From Joynt, Clinical Neurology, 1998, Ch27, pp46-50) |
| Synonym | brain cysticercosis central nervous system cysticercosis cerebral cysticercosis cerebral cysticercosis (disorder) cns cysticercosis cysticercosis cns cysticercosis of central nervous system cysticercosis of central nervous system (disorder) cysticercosis, brain cysticercosis, central nervous system neurocysticercoses neurocysticercosis [disease/finding] |
| DOID | |
| ICD10 | |
| UMLS | C0338437 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:15) C0014544 | epilepsy | 13 C0014544 | epileptic seizures | 3 C0014544 | epileptic seizure | 3 C0020255 | hydrocephalus | 3 C0021053 | immune dysfunction | 2 C0151311 | cranial nerve palsy | 1 C0037280 | infestation | 1 C0030442 | bulbar palsy | 1 C1621958 | glioblastoma multiforme | 1 C0029124 | optic atrophy | 1 C0033790 | pseudobulbar palsy | 1 C0032000 | pituitary adenoma | 1 C0010678 | cysticercosis | 1 C0497327 | dementia | 1 C0017636 | glioblastoma | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | (Waiting for update.) |
| Locus | (Waiting for update.) |
| Disease ID | 1295 |
|---|---|
| Disease | neurocysticercosis |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:21) HP:0001250 | Seizures | 10 HP:0000238 | Nonsyndromal hydrocephalus | 3 HP:0009733 | Glioma | 2 HP:0002617 | Aneurysmal dilatation | 1 HP:0011856 | Pica | 1 HP:0000648 | Optic-nerve degeneration | 1 HP:0007024 | Pseudobulbar palsy | 1 HP:0030692 | Brain tumor | 1 HP:0012174 | Glioblastoma multiforme | 1 HP:0100843 | Glioblastoma | 1 HP:0002721 | Immunodeficiency | 1 HP:0001297 | Cerebral vascular events | 1 HP:0100248 | Hemiballismus | 1 HP:0001283 | Bulbar palsies | 1 HP:0006824 | Cranial nerve palsy | 1 HP:0002893 | Pituitary adenoma | 1 HP:0011450 | CNS infection | 1 HP:0000738 | Sensory hallucination | 1 HP:0000726 | Dementia | 1 HP:0002367 | Visual hallucinations | 1 HP:0002315 | Headaches | 1 |
| Disease ID | 1295 |
|---|---|
| Disease | neurocysticercosis |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:10) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
All Snps(Total Genotypes:1) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs5498 | 25128351 | 3383 | ICAM1 | umls:C0338437 | BeFree | Association of ICAM-1 K469E polymorphism with neurocysticercosis. | 0.000542884 | 2014 | ICAM1;ICAM4;LOC105372272 | 19 | 10285007 | A | G |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
|---|
| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
Chemical(Total Drugs:2) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0338437 | albendazole | D015766 | 54965-21-8 | neurocysticercosis | MESH:D020019 | marker/mechanism | 17304744 | ||
| C0338437 | albendazole | D015766 | 54965-21-8 | neurocysticercosis | MESH:D020019 | therapeutic | 11565520 | ||
FDA approved drug and dosage information(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
|---|---|
| (Waiting for update.) | |