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PedAM

Pediatric Disease Annotations & Medicines



   neurilemmoma
  

Disease ID 1067
Disease neurilemmoma
Definition
A neoplasm that arises from SCHWANN CELLS of the cranial, peripheral, and autonomic nerves. Clinically, these tumors may present as a cranial neuropathy, abdominal or soft tissue mass, intracranial lesion, or with spinal cord compression. Histologically, these tumors are encapsulated, highly vascular, and composed of a homogenous pattern of biphasic fusiform-shaped cells that may have a palisaded appearance. (From DeVita Jr et al., Cancer: Principles and Practice of Oncology, 5th ed, pp964-5)
Synonym
ancient schwannoma
benign neurilemmoma
benign schwannoma
neurilemmoma (disorder)
neurilemmoma [disease/finding]
neurilemmoma, nos
neurilemmomas
neurilemoma
neurilemoma (morphologic abnormality)
neurilemomas
neurinoma
neurinomas
neurolemmoma
psammomatous schwannoma
schwann cell tumor
schwann cell tumour
schwannoma
schwannoma (disorder)
schwannoma (who grade i)
schwannoma, benign
schwannoma, nos
schwannomas
Orphanet
DOID
UMLS
C0027809
MeSH
SNOMED-CT
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:1)
C0947622  |  cholecystolithiasis  |  1
Curated Gene
Entrez_id | Symbol | Resource(Total Genes:5)
NF1  |  4763  |  CTD_human
WT1  |  7490  |  CTD_human
SUZ12  |  23512  |  CTD_human
AXL  |  558  |  CTD_human
EED  |  8726  |  CTD_human
Inferring Gene(Waiting for update.)
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:210)
2288  |  FKBP4  |  DISEASES
6405  |  SEMA3F  |  DISEASES
6515  |  SLC2A3  |  DISEASES
4804  |  NGFR  |  DISEASES
359  |  AQP2  |  DISEASES
8216  |  LZTR1  |  DISEASES
1113  |  CHGA  |  DISEASES
7040  |  TGFB1  |  DISEASES
595  |  CCND1  |  DISEASES
5829  |  PXN  |  DISEASES
2735  |  GLI1  |  DISEASES
2026  |  ENO2  |  DISEASES
4172  |  MCM3  |  DISEASES
4759  |  NEU2  |  DISEASES
6549  |  SLC9A2  |  DISEASES
10342  |  TFG  |  DISEASES
56829  |  ZC3HAV1  |  DISEASES
1959  |  EGR2  |  DISEASES
79441  |  HAUS3  |  DISEASES
4246  |  SCGB2A1  |  DISEASES
652  |  BMP4  |  DISEASES
968  |  CD68  |  DISEASES
9113  |  LATS1  |  DISEASES
2670  |  GFAP  |  DISEASES
9695  |  EDEM1  |  DISEASES
10752  |  CHL1  |  DISEASES
2346  |  FOLH1  |  DISEASES
5156  |  PDGFRA  |  DISEASES
51050  |  PI15  |  DISEASES
59341  |  TRPV4  |  DISEASES
5159  |  PDGFRB  |  DISEASES
466  |  ATF1  |  DISEASES
6521  |  SLC4A1  |  DISEASES
6558  |  SLC12A2  |  DISEASES
6132  |  RPL8  |  DISEASES
9368  |  SLC9A3R1  |  DISEASES
9132  |  KCNQ4  |  DISEASES
5595  |  MAPK3  |  DISEASES
6598  |  SMARCB1  |  DISEASES
4438  |  MSH4  |  DISEASES
6855  |  SYP  |  DISEASES
7299  |  TYR  |  DISEASES
4811  |  NID1  |  DISEASES
2247  |  FGF2  |  DISEASES
3371  |  TNC  |  DISEASES
1950  |  EGF  |  DISEASES
64374  |  SIL1  |  DISEASES
51411  |  BIN2  |  DISEASES
6601  |  SMARCC2  |  DISEASES
2065  |  ERBB3  |  DISEASES
7157  |  TP53  |  DISEASES
2064  |  ERBB2  |  DISEASES
56006  |  SMG9  |  DISEASES
207  |  AKT1  |  DISEASES
963  |  CD53  |  DISEASES
83872  |  HMCN1  |  DISEASES
9869  |  SETDB1  |  DISEASES
1956  |  EGFR  |  DISEASES
23196  |  FAM120A  |  DISEASES
4851  |  NOTCH1  |  DISEASES
823  |  CAPN1  |  DISEASES
498  |  ATP5A1  |  DISEASES
7345  |  UCHL1  |  DISEASES
2776  |  GNAQ  |  DISEASES
3815  |  KIT  |  DISEASES
3837  |  KPNB1  |  DISEASES
5152  |  PDE9A  |  DISEASES
6285  |  S100B  |  DISEASES
6271  |  S100A1  |  DISEASES
3889  |  KRT83  |  DISEASES
10630  |  PDPN  |  DISEASES
4286  |  MITF  |  DISEASES
134147  |  CMBL  |  DISEASES
222962  |  SLC29A4  |  DISEASES
5346  |  PLIN1  |  DISEASES
4665  |  NAB2  |  DISEASES
146434  |  ZNF597  |  DISEASES
9101  |  USP8  |  DISEASES
2339  |  FNTA  |  DISEASES
23450  |  SF3B3  |  DISEASES
794  |  CALB2  |  DISEASES
27087  |  B3GAT1  |  DISEASES
2147  |  F2  |  DISEASES
5376  |  PMP22  |  DISEASES
5566  |  PRKACA  |  DISEASES
947  |  CD34  |  DISEASES
5151  |  PDE8A  |  DISEASES
55279  |  ZNF654  |  DISEASES
64236  |  PDLIM2  |  DISEASES
5062  |  PAK2  |  DISEASES
998  |  CDC42  |  DISEASES
23512  |  SUZ12  |  DISEASES
4684  |  NCAM1  |  DISEASES
83787  |  ARMC10  |  DISEASES
5315  |  PKM  |  DISEASES
363  |  AQP6  |  DISEASES
8289  |  ARID1A  |  DISEASES
149830  |  PRNT  |  DISEASES
3039  |  HBA1  |  DISEASES
6605  |  SMARCE1  |  DISEASES
5241  |  PGR  |  DISEASES
64764  |  CREB3L2  |  DISEASES
3855  |  KRT7  |  DISEASES
10215  |  OLIG2  |  DISEASES
63827  |  BCAN  |  DISEASES
7490  |  WT1  |  DISEASES
5271  |  SERPINB8  |  DISEASES
51004  |  COQ6  |  DISEASES
27445  |  PCLO  |  DISEASES
25788  |  RAD54B  |  DISEASES
57820  |  CCNB1IP1  |  DISEASES
554  |  AVPR2  |  DISEASES
23583  |  SMUG1  |  DISEASES
7430  |  EZR  |  DISEASES
3985  |  LIMK2  |  DISEASES
55274  |  PHF10  |  DISEASES
2066  |  ERBB4  |  DISEASES
10181  |  RBM5  |  DISEASES
92399  |  MRRF  |  DISEASES
20  |  ABCA2  |  DISEASES
57492  |  ARID1B  |  DISEASES
4771  |  NF2  |  DISEASES
2551  |  GABPA  |  DISEASES
8650  |  NUMB  |  DISEASES
55107  |  ANO1  |  DISEASES
4698  |  NDUFA5  |  DISEASES
9644  |  SH3PXD2A  |  DISEASES
3084  |  NRG1  |  DISEASES
1108  |  CHD4  |  DISEASES
4763  |  NF1  |  DISEASES
5573  |  PRKAR1A  |  DISEASES
23607  |  CD2AP  |  DISEASES
8936  |  WASF1  |  DISEASES
6832  |  SUPV3L1  |  DISEASES
4151  |  MB  |  DISEASES
2157  |  F8  |  DISEASES
4478  |  MSN  |  DISEASES
4311  |  MME  |  DISEASES
6663  |  SOX10  |  DISEASES
800  |  CALD1  |  DISEASES
9542  |  NRG2  |  DISEASES
1270  |  CNTF  |  DISEASES
284129  |  SLC26A11  |  DISEASES
5788  |  PTPRC  |  DISEASES
10763  |  NES  |  DISEASES
1944  |  EFNA3  |  DISEASES
4803  |  NGF  |  DISEASES
9446  |  GSTO1  |  DISEASES
51684  |  SUFU  |  DISEASES
51750  |  RTEL1  |  DISEASES
4923  |  NTSR1  |  DISEASES
5567  |  PRKACB  |  DISEASES
81030  |  ZBP1  |  DISEASES
1791  |  DNTT  |  DISEASES
4774  |  NFIA  |  DISEASES
29991  |  OBP2A  |  DISEASES
7422  |  VEGFA  |  DISEASES
9783  |  RIMS3  |  DISEASES
5453  |  POU3F1  |  DISEASES
139596  |  UPRT  |  DISEASES
7321  |  UBE2D1  |  DISEASES
400746  |  NCMAP  |  DISEASES
5081  |  PAX7  |  DISEASES
727837  |  SSX2B  |  DISEASES
114769  |  CARD16  |  DISEASES
8874  |  ARHGEF7  |  DISEASES
7088  |  TLE1  |  DISEASES
5935  |  RBM3  |  DISEASES
7161  |  TP73  |  DISEASES
1832  |  DSP  |  DISEASES
116840  |  CNTROB  |  DISEASES
10087  |  COL4A3BP  |  DISEASES
8623  |  ASMTL  |  DISEASES
2315  |  MLANA  |  DISEASES
192668  |  CYS1  |  DISEASES
10188  |  TNK2  |  DISEASES
116448  |  OLIG1  |  DISEASES
4155  |  MBP  |  DISEASES
388698  |  FLG2  |  DISEASES
9244  |  CRLF1  |  DISEASES
196410  |  METTL7B  |  DISEASES
6164  |  RPL34  |  DISEASES
65010  |  SLC26A6  |  DISEASES
144195  |  SLC2A14  |  DISEASES
29998  |  GLTSCR1  |  DISEASES
4338  |  MOCS2  |  DISEASES
4784  |  NFIX  |  DISEASES
5609  |  MAP2K7  |  DISEASES
1415  |  CRYBB2  |  DISEASES
4626  |  MYH8  |  DISEASES
4776  |  NFATC4  |  DISEASES
146713  |  RBFOX3  |  DISEASES
1029  |  CDKN2A  |  DISEASES
960  |  CD44  |  DISEASES
3908  |  LAMA2  |  DISEASES
2668  |  GDNF  |  DISEASES
3850  |  KRT3  |  DISEASES
6513  |  SLC2A1  |  DISEASES
4193  |  MDM2  |  DISEASES
51555  |  PEX5L  |  DISEASES
5164  |  PDK2  |  DISEASES
11275  |  KLHL2  |  DISEASES
83697  |  SLC4A9  |  DISEASES
7033  |  TFF3  |  DISEASES
100423062  |  IGLL5  |  DISEASES
996  |  CDC27  |  DISEASES
6207  |  RPS13  |  DISEASES
4782  |  NFIC  |  DISEASES
102723508  |  KANTR  |  DISEASES
79104  |  MEG8  |  DISEASES
Locus(Waiting for update.)
Disease ID 1067
Disease neurilemmoma
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:1)
HP:0002664  |  Neoplasia  |  1
Disease ID 1067
Disease neurilemmoma
Manually Symptom(Waiting for update.)
Text Mined Symptom(Waiting for update.)
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:1)
snpId pubmedId geneId geneSymbol diseaseId sourceId sentence score Year geneSymbol_dbSNP CHROMOSOME POS REF ALT
rs121913530231901543845KRASumls:C0027809BeFreeA KRAS G12S mutation was also evident in one sporadic schwannoma.0.0002714422013KRAS1225245351CT,G,A
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)
Mapped by lexical matching(Total Items:0)
(Waiting for update.)
Mapped by homologous gene(Total Items:0)
(Waiting for update.)
Chemical(Total Drugs:2)
CUI ChemicalName ChemicalID CasRN DiseaseName DiseaseID DirectEvidence PubMedIDs
C0027809carmustineD002330154-93-8neurilemmomaMESH:D009442therapeutic175631
C0027809ifosfamideD0070693778-73-2neurilemmomaMESH:D009442therapeutic2567921
FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)
FDA labeling changes(Total Drugs:0)
(Waiting for update.)