PedAM

Pediatric Disease Annotations & Medicines


	nephrosis

Disease ID	1264
Disease	nephrosis
Definition	Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA.
Synonym	#NAME? nephroses nephrosis [disease/finding] nephrosis nos nephrosis, nos
DOID	DOID:2527
UMLS	C0027720
MeSH	D009401
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:6) C0027697 \| nephritis \| 1 C0033687 \| proteinuria \| 1 C0017665 \| membranous nephropathy \| 1 C0041960 \| ureterocele \| 1 C0039128 \| syphilis \| 1 C0017658 \| glomerulonephritis \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:15) SOD1 \| 6647 \| CTD_human ICAM1 \| 3383 \| CTD_human F2 \| 2147 \| CTD_human EDN1 \| 1906 \| CTD_human AGT \| 183 \| CTD_human NPHS2 \| 7827 \| CTD_human DES \| 1674 \| CTD_human ALB \| 213 \| CTD_human VIM \| 7431 \| CTD_human ITGB2 \| 3689 \| CTD_human EDNRB \| 1910 \| CTD_human DDIT3 \| 1649 \| CTD_human NES \| 10763 \| CTD_human REN \| 5972 \| CTD_human HPSE \| 10855 \| CTD_human
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:2) 3565 \| IL4 \| infer 7827 \| NPHS2 \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:376) 3675 \| ITGA3 \| DISEASES 5536 \| PPP5C \| DISEASES 1015 \| CDH17 \| DISEASES 608 \| TNFRSF17 \| DISEASES 340533 \| KIAA2022 \| DISEASES 3566 \| IL4R \| DISEASES 53405 \| CLIC5 \| DISEASES 359 \| AQP2 \| DISEASES 1071 \| CETP \| DISEASES 3053 \| SERPIND1 \| DISEASES 4282 \| MIF \| DISEASES 57026 \| PDXP \| DISEASES 4627 \| MYH9 \| DISEASES 412 \| STS \| DISEASES 2158 \| F9 \| DISEASES 7076 \| TIMP1 \| DISEASES 4210 \| MEFV \| DISEASES 8797 \| TNFRSF10A \| DISEASES 2217 \| FCGRT \| DISEASES 7040 \| TGFB1 \| DISEASES 973 \| CD79A \| DISEASES 5444 \| PON1 \| DISEASES 5054 \| SERPINE1 \| DISEASES 113263 \| GLCCI1 \| DISEASES 4353 \| MPO \| DISEASES 6347 \| CCL2 \| DISEASES 7448 \| VTN \| DISEASES 173 \| AFM \| DISEASES 3558 \| IL2 \| DISEASES 345 \| APOC3 \| DISEASES 3458 \| IFNG \| DISEASES 57122 \| NUP107 \| DISEASES 2597 \| GAPDH \| DISEASES 55907 \| CMAS \| DISEASES 3565 \| IL4 \| DISEASES 2908 \| NR3C1 \| DISEASES 3273 \| HRG \| DISEASES 7035 \| TFPI \| DISEASES 338 \| APOB \| DISEASES 3485 \| IGFBP2 \| DISEASES 5657 \| PRTN3 \| DISEASES 335 \| APOA1 \| DISEASES 7276 \| TTR \| DISEASES 5311 \| PKD2 \| DISEASES 29094 \| LGALSL \| DISEASES 847 \| CAT \| DISEASES 718 \| C3 \| DISEASES 10047 \| CST8 \| DISEASES 5199 \| CFP \| DISEASES 391013 \| PLA2G2C \| DISEASES 3315 \| HSPB1 \| DISEASES 968 \| CD68 \| DISEASES 3630 \| INS \| DISEASES 80714 \| PBX4 \| DISEASES 5894 \| RAF1 \| DISEASES 348 \| APOE \| DISEASES 81 \| ACTN4 \| DISEASES 2056 \| EPO \| DISEASES 3911 \| LAMA5 \| DISEASES 10343 \| PKDREJ \| DISEASES 2161 \| F12 \| DISEASES 50617 \| ATP6V0A4 \| DISEASES 1401 \| CRP \| DISEASES 325 \| APCS \| DISEASES 6341 \| SCO1 \| DISEASES 4608 \| MYBPH \| DISEASES 123811 \| FOPNL \| DISEASES 271 \| AMPD2 \| DISEASES 81494 \| CFHR5 \| DISEASES 4677 \| NARS \| DISEASES 2799 \| GNS \| DISEASES 5279 \| PIGC \| DISEASES 3569 \| IL6 \| DISEASES 3557 \| IL1RN \| DISEASES 27179 \| IL36A \| DISEASES 27283 \| TINAG \| DISEASES 51196 \| PLCE1 \| DISEASES 9360 \| PPIG \| DISEASES 4069 \| LYZ \| DISEASES 29121 \| CLEC2D \| DISEASES 55746 \| NUP133 \| DISEASES 7450 \| VWF \| DISEASES 57534 \| MIB1 \| DISEASES 949 \| SCARB1 \| DISEASES 9172 \| MYOM2 \| DISEASES 4092 \| SMAD7 \| DISEASES 4087 \| SMAD2 \| DISEASES 56052 \| ALG1 \| DISEASES 57017 \| COQ9 \| DISEASES 25939 \| SAMHD1 \| DISEASES 23523 \| CABIN1 \| DISEASES 3553 \| IL1B \| DISEASES 6403 \| SELP \| DISEASES 4036 \| LRP2 \| DISEASES 3791 \| KDR \| DISEASES 3931 \| LCAT \| DISEASES 941 \| CD80 \| DISEASES 8916 \| HERC3 \| DISEASES 23530 \| NNT \| DISEASES 3818 \| KLKB1 \| DISEASES 5443 \| POMC \| DISEASES 3383 \| ICAM1 \| DISEASES 6550 \| SLC9A3 \| DISEASES 3827 \| KNG1 \| DISEASES 259 \| AMBP \| DISEASES 56302 \| TRPV5 \| DISEASES 6595 \| SMARCA2 \| DISEASES 3263 \| HPX \| DISEASES 8128 \| ST8SIA2 \| DISEASES 8826 \| IQGAP1 \| DISEASES 6687 \| SPG7 \| DISEASES 396 \| ARHGDIA \| DISEASES 5972 \| REN \| DISEASES 185 \| AGTR1 \| DISEASES 10699 \| CORIN \| DISEASES 10788 \| IQGAP2 \| DISEASES 3439 \| IFNA1 \| DISEASES 3934 \| LCN2 \| DISEASES 2206 \| MS4A2 \| DISEASES 3606 \| IL18 \| DISEASES 5800 \| PTPRO \| DISEASES 7082 \| TJP1 \| DISEASES 5741 \| PTH \| DISEASES 130271 \| PLEKHH2 \| DISEASES 22925 \| PLA2R1 \| DISEASES 55079 \| FEZF2 \| DISEASES 8526 \| DGKE \| DISEASES 23165 \| NUP205 \| DISEASES 2040 \| STOM \| DISEASES 3156 \| HMGCR \| DISEASES 4643 \| MYO1E \| DISEASES 4690 \| NCK1 \| DISEASES 1636 \| ACE \| DISEASES 56894 \| AGPAT3 \| DISEASES 3046 \| HBE1 \| DISEASES 6352 \| CCL5 \| DISEASES 58191 \| CXCL16 \| DISEASES 10630 \| PDPN \| DISEASES 2215 \| FCGR3B \| DISEASES 4880 \| NPPC \| DISEASES 213 \| ALB \| DISEASES 5473 \| PPBP \| DISEASES 5196 \| PF4 \| DISEASES 7098 \| TLR3 \| DISEASES 6862 \| T \| DISEASES 1345 \| COX6C \| DISEASES 55582 \| KIF27 \| DISEASES 11244 \| ZHX1 \| DISEASES 360 \| AQP3 \| DISEASES 5267 \| SERPINA4 \| DISEASES 3611 \| ILK \| DISEASES 7184 \| HSP90B1 \| DISEASES 6778 \| STAT6 \| DISEASES 90678 \| LRSAM1 \| DISEASES 51117 \| COQ4 \| DISEASES 51129 \| ANGPTL4 \| DISEASES 92483 \| LDHAL6B \| DISEASES 253959 \| RALGAPA1 \| DISEASES 3479 \| IGF1 \| DISEASES 255738 \| PCSK9 \| DISEASES 43 \| ACHE \| DISEASES 8988 \| HSPB3 \| DISEASES 1493 \| CTLA4 \| DISEASES 3596 \| IL13 \| DISEASES 4330 \| MN1 \| DISEASES 9655 \| SOCS5 \| DISEASES 7369 \| UMOD \| DISEASES 157570 \| ESCO2 \| DISEASES 9836 \| LCMT2 \| DISEASES 54205 \| CYCS \| DISEASES 2147 \| F2 \| DISEASES 5340 \| PLG \| DISEASES 23529 \| CLCF1 \| DISEASES 4023 \| LPL \| DISEASES 947 \| CD34 \| DISEASES 9688 \| NUP93 \| DISEASES 9024 \| BRSK2 \| DISEASES 27235 \| COQ2 \| DISEASES 4118 \| MAL \| DISEASES 836 \| CASP3 \| DISEASES 358 \| AQP1 \| DISEASES 5319 \| PLA2G1B \| DISEASES 1605 \| DAG1 \| DISEASES 404217 \| CTXN1 \| DISEASES 998 \| CDC42 \| DISEASES 22882 \| ZHX2 \| DISEASES 1191 \| CLU \| DISEASES 3936 \| LCP1 \| DISEASES 8542 \| APOL1 \| DISEASES 9377 \| COX5A \| DISEASES 5652 \| PRSS8 \| DISEASES 4018 \| LPA \| DISEASES 5345 \| SERPINF2 \| DISEASES 64089 \| SNX16 \| DISEASES 2 \| A2M \| DISEASES 9622 \| KLK4 \| DISEASES 6097 \| RORC \| DISEASES 4094 \| MAF \| DISEASES 6906 \| SERPINA7 \| DISEASES 2811 \| GP1BA \| DISEASES 7490 \| WT1 \| DISEASES 8214 \| DGCR6 \| DISEASES 1287 \| COL4A5 \| DISEASES 55328 \| RNLS \| DISEASES 51004 \| COQ6 \| DISEASES 342184 \| FMN1 \| DISEASES 2152 \| F3 \| DISEASES 23760 \| PITPNB \| DISEASES 3320 \| HSP90AA1 \| DISEASES 375318 \| AQP12A \| DISEASES 8710 \| SERPINB7 \| DISEASES 554 \| AVPR2 \| DISEASES 64412 \| GZF1 \| DISEASES 5269 \| SERPINB6 \| DISEASES 7430 \| EZR \| DISEASES 5329 \| PLAUR \| DISEASES 3117 \| HLA-DQA1 \| DISEASES 6609 \| SMPD1 \| DISEASES 7225 \| TRPC6 \| DISEASES 4306 \| NR3C2 \| DISEASES 6187 \| RPS2 \| DISEASES 1508 \| CTSB \| DISEASES 866 \| SERPINA6 \| DISEASES 5498 \| PPOX \| DISEASES 26762 \| HAVCR1 \| DISEASES 9863 \| MAGI2 \| DISEASES 2534 \| FYN \| DISEASES 2335 \| FN1 \| DISEASES 79661 \| NEIL1 \| DISEASES 954 \| ENTPD2 \| DISEASES 4010 \| LMX1B \| DISEASES 7328 \| UBE2H \| DISEASES 1785 \| DNM2 \| DISEASES 26503 \| SLC17A5 \| DISEASES 5265 \| SERPINA1 \| DISEASES 3240 \| HP \| DISEASES 6288 \| SAA1 \| DISEASES 92359 \| CRB3 \| DISEASES 50485 \| SMARCAL1 \| DISEASES 60 \| ACTB \| DISEASES 23556 \| PIGN \| DISEASES 5699 \| PSMB10 \| DISEASES 55243 \| KIRREL \| DISEASES 23607 \| CD2AP \| DISEASES 2013 \| EMP2 \| DISEASES 4151 \| MB \| DISEASES 84063 \| KIRREL2 \| DISEASES 4311 \| MME \| DISEASES 6238 \| RRBP1 \| DISEASES 6721 \| SREBF2 \| DISEASES 10724 \| MGEA5 \| DISEASES 23038 \| WDTC1 \| DISEASES 183 \| AGT \| DISEASES 22796 \| COG2 \| DISEASES 28514 \| DLL1 \| DISEASES 1378 \| CR1 \| DISEASES 5788 \| PTPRC \| DISEASES 3075 \| CFH \| DISEASES 9213 \| XPR1 \| DISEASES 7827 \| NPHS2 \| DISEASES 462 \| SERPINC1 \| DISEASES 6446 \| SGK1 \| DISEASES 2214 \| FCGR3A \| DISEASES 1490 \| CTGF \| DISEASES 336 \| APOA2 \| DISEASES 632 \| BGLAP \| DISEASES 284486 \| THEM5 \| DISEASES 4942 \| OAT \| DISEASES 57107 \| PDSS2 \| DISEASES 914 \| CD2 \| DISEASES 128344 \| PIFO \| DISEASES 3744 \| KCNA10 \| DISEASES 50814 \| NSDHL \| DISEASES 1369 \| CPN1 \| DISEASES 2334 \| AFF2 \| DISEASES 959 \| CD40LG \| DISEASES 27329 \| ANGPTL3 \| DISEASES 163782 \| KANK4 \| DISEASES 953 \| ENTPD1 \| DISEASES 7422 \| VEGFA \| DISEASES 2889 \| RAPGEF1 \| DISEASES 958 \| CD40 \| DISEASES 2981 \| GUCA2B \| DISEASES 8879 \| SGPL1 \| DISEASES 23051 \| ZHX3 \| DISEASES 286204 \| CRB2 \| DISEASES 4702 \| NDUFA8 \| DISEASES 2934 \| GSN \| DISEASES 27293 \| SMPDL3B \| DISEASES 7099 \| TLR4 \| DISEASES 1896 \| EDA \| DISEASES 3339 \| HSPG2 \| DISEASES 3118 \| HLA-DQA2 \| DISEASES 23352 \| UBR4 \| DISEASES 2155 \| F7 \| DISEASES 50943 \| FOXP3 \| DISEASES 23590 \| PDSS1 \| DISEASES 7133 \| TNFRSF1B \| DISEASES 4878 \| NPPA \| DISEASES 3105 \| HLA-A \| DISEASES 1471 \| CST3 \| DISEASES 2262 \| GPC5 \| DISEASES 7056 \| THBD \| DISEASES 8718 \| TNFRSF25 \| DISEASES 83715 \| ESPN \| DISEASES 8029 \| CUBN \| DISEASES 6520 \| SLC3A2 \| DISEASES 5420 \| PODXL \| DISEASES 4868 \| NPHS1 \| DISEASES 375790 \| AGRN \| DISEASES 1906 \| EDN1 \| DISEASES 79886 \| CAAP1 \| DISEASES 3440 \| IFNA2 \| DISEASES 3456 \| IFNB1 \| DISEASES 551 \| AVP \| DISEASES 150084 \| IGSF5 \| DISEASES 6557 \| SLC12A1 \| DISEASES 3486 \| IGFBP3 \| DISEASES 8908 \| GYG2 \| DISEASES 55858 \| TMEM165 \| DISEASES 23189 \| KANK1 \| DISEASES 402682 \| UFSP1 \| DISEASES 64423 \| INF2 \| DISEASES 11346 \| SYNPO \| DISEASES 3426 \| CFI \| DISEASES 5530 \| PPP3CA \| DISEASES 6696 \| SPP1 \| DISEASES 174 \| AFP \| DISEASES 1285 \| COL4A3 \| DISEASES 1286 \| COL4A4 \| DISEASES 30011 \| SH3KBP1 \| DISEASES 340990 \| OTOG \| DISEASES 11281 \| POU6F2 \| DISEASES 10525 \| HYOU1 \| DISEASES 5970 \| RELA \| DISEASES 7018 \| TF \| DISEASES 221935 \| SDK1 \| DISEASES 4648 \| MYO7B \| DISEASES 10213 \| PSMD14 \| DISEASES 154810 \| AMOTL1 \| DISEASES 84942 \| WDR73 \| DISEASES 11277 \| TREX1 \| DISEASES 23109 \| DDN \| DISEASES 6457 \| SH3GL3 \| DISEASES 197 \| AHSG \| DISEASES 5005 \| ORM2 \| DISEASES 25959 \| KANK2 \| DISEASES 5076 \| PAX2 \| DISEASES 960 \| CD44 \| DISEASES 7124 \| TNF \| DISEASES 3106 \| HLA-B \| DISEASES 387 \| RHOA \| DISEASES 6559 \| SLC12A3 \| DISEASES 2195 \| FAT1 \| DISEASES 221981 \| THSD7A \| DISEASES 9351 \| SLC9A3R2 \| DISEASES 8867 \| SYNJ1 \| DISEASES 389549 \| FEZF1 \| DISEASES 3586 \| IL10 \| DISEASES 55230 \| USP40 \| DISEASES 721 \| C4B \| DISEASES 629 \| CFB \| DISEASES 2638 \| GC \| DISEASES 51428 \| DDX41 \| DISEASES 373156 \| GSTK1 \| DISEASES 917 \| CD3G \| DISEASES 1207 \| CLNS1A \| DISEASES 84623 \| KIRREL3 \| DISEASES 4798 \| NFRKB \| DISEASES 930 \| CD19 \| DISEASES 80790 \| CMIP \| DISEASES 8972 \| MGAM \| DISEASES 4157 \| MC1R \| DISEASES 567 \| B2M \| DISEASES 6139 \| RPL17 \| DISEASES 344 \| APOC2 \| DISEASES
Locus	(Waiting for update.)

Disease ID	1264
Disease	nephrosis
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:8) HP:0001919 \| Acute renal failure \| 2 HP:0002119 \| Ventricular dilatation \| 1 HP:0000969 \| Dropsy \| 1 HP:0012578 \| Membranous glomerulonephritis \| 1 HP:0000093 \| Proteinuria \| 1 HP:0000123 \| Nephritis \| 1 HP:0000099 \| Glomerular nephritis \| 1 HP:0000070 \| Ureterocele \| 1

Disease ID	1264
Disease	nephrosis
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:1) C0033687 \| proteinuria \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:9)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0027720	acetohexamide	D000092	968-81-0	nephrosis	MESH:D009401	therapeutic	473209
C0027720	cyclophosphamide	D003520	50-18-0	nephrosis	MESH:D009401	therapeutic	4961747
C0027720	indomethacin	D007213	53-86-1	nephrosis	MESH:D009401	marker/mechanism	6618773
C0027720	oxytetracycline	D010118	79-57-2	nephrosis	MESH:D009401	marker/mechanism	8905581
C0027720	phenylephrine	D010656	59-42-7	nephrosis	MESH:D009401	marker/mechanism	10406839
C0027720	tacrolimus	D016559	109581-93-3	nephrosis	MESH:D009401	therapeutic	1375300
C0027720	tretinoin	D014212	302-79-4	nephrosis	MESH:D009401	marker/mechanism	12660332
C0027720	trimethadione	D014293	127-48-0	nephrosis	MESH:D009401	marker/mechanism	4961747
C0027720	vitamin a	D014801	11103-57-4	nephrosis	MESH:D009401	marker/mechanism	12660332

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

Web
Analytics