PedAM

Pediatric Disease Annotations & Medicines


	myositis

Disease ID	177
Disease	myositis
Definition	Inflammation of a muscle or muscle tissue.
Synonym	inflamm muscle dis inflamm myopathy inflammation of the skeletal muscle inflammatory disorder of muscle inflammatory disorder of muscle (disorder) inflammatory muscle disease inflammatory muscle diseases inflammatory myopathies inflammatory myopathy inflammatory myopathy nos muscle dis inflamm muscle disease, inflammatory muscle diseases, inflammatory muscle inflammation myopathies, inflammatory myopathy inflamm myopathy, inflammatory myositides myositis (disorder) myositis [disease/finding] myositis nos myositis unspecified myositis unspecified (disorder) myositis, nos
OMIM	OMIM:160750
DOID	DOID:633
UMLS	C0027121
MeSH	D009220
SNOMED-CT	SNOMEDCT_US_2016_09_01:128496001;SNOMEDCT_US_2016_09_01:26889001
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:119) C0409974 \| lupus erythematosus \| 5 C0024115 \| lung disease \| 4 C0003864 \| arthritis \| 4 C0206062 \| interstitial lung disease \| 4 C0003873 \| rheumatoid arthritis \| 4 C0026850 \| muscular dystrophy \| 4 C0021400 \| influenza \| 4 C0029401 \| paget's disease \| 4 C0027121 \| inflammatory myopathy \| 3 C0024141 \| systemic lupus erythematosus \| 3 C0029089 \| ophthalmoplegia \| 3 C0009782 \| connective tissue disease \| 3 C0036421 \| systemic sclerosis \| 3 C0029463 \| osteosarcoma \| 2 C0029401 \| paget's disease of the bone \| 2 C0015645 \| fasciitis \| 2 C0015230 \| rash \| 2 C1527336 \| sjogren's syndrome \| 2 C0022660 \| acute renal failure \| 2 C0023418 \| leukemia \| 2 C0010346 \| crohn's disease \| 2 C0027059 \| myocarditis \| 2 C0032285 \| pneumonia \| 2 C0040896 \| trichinellosis \| 2 C0009319 \| colitis \| 2 C0011603 \| dermatitis \| 2 C0026848 \| myopathy \| 2 C0034735 \| raynaud's phenomenon \| 2 C0023473 \| chronic myeloid leukemia \| 1 C0270952 \| oculopharyngeal muscular dystrophy \| 1 C0032541 \| polyneuritis \| 1 C0042373 \| vascular disorders \| 1 C0023470 \| myeloid leukemia \| 1 C0029132 \| optic neuropathy \| 1 C0027868 \| neuromuscular disease \| 1 C0026846 \| muscle atrophy \| 1 C0085273 \| parvovirus b19 infection \| 1 C0024143 \| lupus nephritis \| 1 C0085273 \| erythema infectiosum \| 1 C0235974 \| pancreatic cancer \| 1 C0034735 \| raynaud phenomenon \| 1 C0398794 \| griscelli syndrome \| 1 C0036202 \| sarcoidosis \| 1 C0031046 \| pericarditis \| 1 C0007102 \| colon cancer \| 1 C0042164 \| intraocular inflammation \| 1 C0027697 \| nephritis \| 1 C1261473 \| sarcoma \| 1 C0043117 \| idiopathic thrombocytopenic purpura \| 1 C0206141 \| hypereosinophilic syndrome \| 1 C0035934 \| rubinstein-taybi syndrome \| 1 C0021845 \| bowel perforation \| 1 C0008728 \| churg-strauss syndrome \| 1 C0027121 \| muscle inflammation \| 1 C0022661 \| chronic renal failure \| 1 C1370740 \| adrenal carcinoma \| 1 C0206180 \| anaplastic large cell lymphoma \| 1 C0541912 \| duodenal ca \| 1 C0023492 \| t-cell leukemia \| 1 C0432528 \| proliferative fasciitis \| 1 C0032285 \| lung inflammation \| 1 C0009324 \| ulcerative colitis \| 1 C0027765 \| nervous system disease \| 1 C0242770 \| cryptogenic organizing pneumonia \| 1 C0042769 \| viral infections \| 1 C0023487 \| acute promyelocytic leukemia \| 1 C0236642 \| pick disease \| 1 C0007138 \| urothelial carcinoma \| 1 C0035078 \| renal failure \| 1 C0002395 \| alzheimer's disease \| 1 C0007682 \| central nervous system disease \| 1 C0005745 \| ptosis \| 1 C0007134 \| renal carcinoma \| 1 C0238190 \| inclusion body myositis \| 1 C0040188 \| tic disorders \| 1 C0020437 \| hypercalcemia \| 1 C1704275 \| pyomyositis \| 1 C0040034 \| thrombocytopenia \| 1 C0018378 \| guillain-barre syndrome \| 1 C0031069 \| familial mediterranean fever \| 1 C0011633 \| dermatomyositis \| 1 C0011644 \| scleroderma \| 1 C0028064 \| niemann-pick disease \| 1 C0004943 \| behcet's disease \| 1 C0019158 \| hepatitis \| 1 C0476089 \| endometrial ca \| 1 C0040100 \| thymoma \| 1 C0023895 \| liver disease \| 1 C0456909 \| vision loss \| 1 C0018801 \| cardiac failure \| 1 C0278846 \| invasive thymoma \| 1 C0023470 \| myelocytic leukemia \| 1 C0042373 \| vascular disorder \| 1 C0235618 \| proliferative glomerulonephritis \| 1 C0027947 \| neutropenia \| 1 C0021390 \| inflammatory bowel disease \| 1 C0018213 \| graves' disease \| 1 C0085655 \| polymyositis \| 1 C0017662 \| membranoproliferative glomerulonephritis \| 1 C0042870 \| vitamin d defic \| 1 C0042769 \| viral infection \| 1 C1258104 \| diffuse systemic sclerosis \| 1 C0017160 \| gastroenteritis \| 1 C0032285 \| pneumoniae \| 1 C0021053 \| immune disease \| 1 C0021831 \| bowel disease \| 1 C0042384 \| angiitis \| 1 C0007194 \| hypertrophic cardiomyopathy \| 1 C0036421 \| systemic scleroderma \| 1 C0206642 \| parosteal osteosarcoma \| 1 C0007570 \| celiac disease \| 1 C0024302 \| large cell lymphoma \| 1 C0476089 \| endometrial carcinoma \| 1 C0026272 \| mixed connective tissue disease \| 1 C0024198 \| lyme disease \| 1 C0023487 \| promyelocytic leukemia \| 1 C0019291 \| hiatus hernia \| 1 C0035412 \| rhabdomyosarcoma \| 1 C0009782 \| connective tissue diseases \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:6) IGKC \| 3514 \| CTD_human IL1RN \| 3557 \| CTD_human TARS \| 6897 \| CTD_human IGHG1 \| 3500 \| CTD_human GNE \| 10020 \| GHR IGHG2 \| 3501 \| CTD_human
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:6) 3117 \| HLA-DQA1 \| infer 3119 \| HLA-DQB1 \| infer 3123 \| HLA-DRB1 \| infer 2214 \| FCGR3A \| infer 3106 \| HLA-B \| infer 26191 \| PTPN22 \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:481) 100379571 \| BACE1-AS \| DISEASES 6362 \| CCL18 \| DISEASES 126393 \| HSPB6 \| DISEASES 6376 \| CX3CL1 \| DISEASES 11345 \| GABARAPL2 \| DISEASES 1634 \| DCN \| DISEASES 7132 \| TNFRSF1A \| DISEASES 10272 \| FSTL3 \| DISEASES 9741 \| LAPTM4A \| DISEASES 27248 \| ERLEC1 \| DISEASES 10777 \| ARPP21 \| DISEASES 11274 \| USP18 \| DISEASES 6948 \| TCN2 \| DISEASES 57026 \| PDXP \| DISEASES 84844 \| PHF5A \| DISEASES 3002 \| GZMB \| DISEASES 8106 \| PABPN1 \| DISEASES 6729 \| SRP54 \| DISEASES 5020 \| OXT \| DISEASES 10857 \| PGRMC1 \| DISEASES 6361 \| CCL17 \| DISEASES 4210 \| MEFV \| DISEASES 123263 \| MTFMT \| DISEASES 8797 \| TNFRSF10A \| DISEASES 3972 \| LHB \| DISEASES 1158 \| CKM \| DISEASES 56729 \| RETN \| DISEASES 2091 \| FBL \| DISEASES 333 \| APLP1 \| DISEASES 7040 \| TGFB1 \| DISEASES 973 \| CD79A \| DISEASES 1311 \| COMP \| DISEASES 6119 \| RPA3 \| DISEASES 146542 \| ZNF688 \| DISEASES 6348 \| CCL3 \| DISEASES 4353 \| MPO \| DISEASES 6347 \| CCL2 \| DISEASES 6357 \| CCL13 \| DISEASES 3381 \| IBSP \| DISEASES 3558 \| IL2 \| DISEASES 969 \| CD69 \| DISEASES 397 \| ARHGDIB \| DISEASES 3458 \| IFNG \| DISEASES 9450 \| LY86 \| DISEASES 10279 \| PRSS16 \| DISEASES 23517 \| SKIV2L2 \| DISEASES 23438 \| HARS2 \| DISEASES 3565 \| IL4 \| DISEASES 3567 \| IL5 \| DISEASES 5657 \| PRTN3 \| DISEASES 6301 \| SARS \| DISEASES 84618 \| NT5C1A \| DISEASES 6402 \| SELL \| DISEASES 9499 \| MYOT \| DISEASES 23435 \| TARDBP \| DISEASES 8161 \| COIL \| DISEASES 4656 \| MYOG \| DISEASES 4852 \| NPY \| DISEASES 64105 \| CENPK \| DISEASES 5184 \| PEPD \| DISEASES 6631 \| SNRPC \| DISEASES 57505 \| AARS2 \| DISEASES 4620 \| MYH2 \| DISEASES 718 \| C3 \| DISEASES 1236 \| CCR7 \| DISEASES 1446 \| CSN1S1 \| DISEASES 85359 \| DGCR6L \| DISEASES 4654 \| MYOD1 \| DISEASES 9098 \| USP6 \| DISEASES 968 \| CD68 \| DISEASES 6351 \| CCL4 \| DISEASES 3630 \| INS \| DISEASES 348 \| APOE \| DISEASES 10452 \| TOMM40 \| DISEASES 4298 \| MLLT1 \| DISEASES 7136 \| TNNI2 \| DISEASES 1160 \| CKMT2 \| DISEASES 2521 \| FUS \| DISEASES 6737 \| TRIM21 \| DISEASES 1401 \| CRP \| DISEASES 10752 \| CHL1 \| DISEASES 10468 \| FST \| DISEASES 4677 \| NARS \| DISEASES 3569 \| IL6 \| DISEASES 640 \| BLK \| DISEASES 3557 \| IL1RN \| DISEASES 55014 \| STX17 \| DISEASES 6366 \| CCL21 \| DISEASES 9177 \| HTR3B \| DISEASES 7057 \| THBS1 \| DISEASES 1559 \| CYP2C9 \| DISEASES 2660 \| MSTN \| DISEASES 6741 \| SSB \| DISEASES 9360 \| PPIG \| DISEASES 30061 \| SLC40A1 \| DISEASES 4069 \| LYZ \| DISEASES 7450 \| VWF \| DISEASES 5687 \| PSMA6 \| DISEASES 6532 \| SLC6A4 \| DISEASES 16 \| AARS \| DISEASES 9172 \| MYOM2 \| DISEASES 10049 \| DNAJB6 \| DISEASES 64377 \| CHST8 \| DISEASES 25939 \| SAMHD1 \| DISEASES 443 \| ASPA \| DISEASES 5024 \| P2RX3 \| DISEASES 3552 \| IL1A \| DISEASES 3553 \| IL1B \| DISEASES 735 \| C9 \| DISEASES 64135 \| IFIH1 \| DISEASES 9066 \| SYT7 \| DISEASES 943 \| TNFRSF8 \| DISEASES 80219 \| COQ10B \| DISEASES 941 \| CD80 \| DISEASES 6476 \| SI \| DISEASES 5709 \| PSMD3 \| DISEASES 54888 \| NSUN2 \| DISEASES 5443 \| POMC \| DISEASES 3383 \| ICAM1 \| DISEASES 6897 \| TARS \| DISEASES 27074 \| LAMP3 \| DISEASES 6595 \| SMARCA2 \| DISEASES 5286 \| PIK3C2A \| DISEASES 23710 \| GABARAPL1 \| DISEASES 80349 \| WDR61 \| DISEASES 146862 \| UNC45B \| DISEASES 7157 \| TP53 \| DISEASES 150094 \| SIK1 \| DISEASES 10055 \| SAE1 \| DISEASES 134864 \| TAAR1 \| DISEASES 1392 \| CRH \| DISEASES 3439 \| IFNA1 \| DISEASES 4851 \| NOTCH1 \| DISEASES 740 \| MRPL49 \| DISEASES 51348 \| KLRF1 \| DISEASES 3606 \| IL18 \| DISEASES 79731 \| NARS2 \| DISEASES 2241 \| FER \| DISEASES 291 \| SLC25A4 \| DISEASES 5741 \| PTH \| DISEASES 7345 \| UCHL1 \| DISEASES 83648 \| FAM167A \| DISEASES 351 \| APP \| DISEASES 129831 \| RBM45 \| DISEASES 10563 \| CXCL13 \| DISEASES 6750 \| SST \| DISEASES 123803 \| NTAN1 \| DISEASES 3156 \| HMGCR \| DISEASES 1636 \| ACE \| DISEASES 115650 \| TNFRSF13C \| DISEASES 10841 \| FTCD \| DISEASES 6294 \| SAFB \| DISEASES 643 \| CXCR5 \| DISEASES 1234 \| CCR5 \| DISEASES 6352 \| CCL5 \| DISEASES 7412 \| VCAM1 \| DISEASES 2215 \| FCGR3B \| DISEASES 3577 \| CXCR1 \| DISEASES 213 \| ALB \| DISEASES 57159 \| TRIM54 \| DISEASES 79443 \| FYCO1 \| DISEASES 3600 \| IL15 \| DISEASES 4724 \| NDUFS4 \| DISEASES 7098 \| TLR3 \| DISEASES 9311 \| ASIC3 \| DISEASES 4714 \| NDUFB8 \| DISEASES 1152 \| CKB \| DISEASES 79803 \| HPS6 \| DISEASES 4314 \| MMP3 \| DISEASES 1159 \| CKMT1B \| DISEASES 6632 \| SNRPD1 \| DISEASES 64127 \| NOD2 \| DISEASES 5617 \| PRL \| DISEASES 79058 \| ASPSCR1 \| DISEASES 6356 \| CCL11 \| DISEASES 56890 \| MDM1 \| DISEASES 7343 \| UBTF \| DISEASES 3479 \| IGF1 \| DISEASES 3308 \| HSPA4 \| DISEASES 140738 \| TMEM37 \| DISEASES 83987 \| CCDC8 \| DISEASES 55699 \| IARS2 \| DISEASES 6869 \| TACR1 \| DISEASES 1493 \| CTLA4 \| DISEASES 171558 \| PTCRA \| DISEASES 7314 \| UBB \| DISEASES 3596 \| IL13 \| DISEASES 3627 \| CXCL10 \| DISEASES 2548 \| GAA \| DISEASES 50515 \| CHST11 \| DISEASES 26287 \| ANKRD2 \| DISEASES 6504 \| SLAMF1 \| DISEASES 2353 \| FOS \| DISEASES 3669 \| ISG20 \| DISEASES 56246 \| MRAP \| DISEASES 64080 \| RBKS \| DISEASES 114990 \| VASN \| DISEASES 6373 \| CXCL11 \| DISEASES 27087 \| B3GAT1 \| DISEASES 6363 \| CCL19 \| DISEASES 947 \| CD34 \| DISEASES 116028 \| RMI2 \| DISEASES 924 \| CD7 \| DISEASES 1605 \| DAG1 \| DISEASES 3952 \| LEP \| DISEASES 5591 \| PRKDC \| DISEASES 2907 \| GRINA \| DISEASES 1831 \| TSC22D3 \| DISEASES 203859 \| ANO5 \| DISEASES 10859 \| LILRB1 \| DISEASES 1776 \| DNASE1L3 \| DISEASES 3350 \| HTR1A \| DISEASES 57381 \| RHOJ \| DISEASES 8607 \| RUVBL1 \| DISEASES 4684 \| NCAM1 \| DISEASES 23621 \| BACE1 \| DISEASES 8834 \| TMEM11 \| DISEASES 80381 \| CD276 \| DISEASES 6863 \| TAC1 \| DISEASES 10615 \| SPAG5 \| DISEASES 7706 \| TRIM25 \| DISEASES 30832 \| ZNF354C \| DISEASES 10250 \| SRRM1 \| DISEASES 79147 \| FKRP \| DISEASES 51330 \| TNFRSF12A \| DISEASES 4094 \| MAF \| DISEASES 117608 \| ZNF354B \| DISEASES 3563 \| IL3RA \| DISEASES 3739 \| KCNA4 \| DISEASES 221937 \| FOXK1 \| DISEASES 3665 \| IRF7 \| DISEASES 1915 \| EEF1A1 \| DISEASES 8214 \| DGCR6 \| DISEASES 6401 \| SELE \| DISEASES 796 \| CALCA \| DISEASES 942 \| CD86 \| DISEASES 79582 \| SPAG16 \| DISEASES 25825 \| BACE2 \| DISEASES 3320 \| HSP90AA1 \| DISEASES 5025 \| P2RX4 \| DISEASES 23336 \| SYNM \| DISEASES 6940 \| ZNF354A \| DISEASES 2036 \| EPB41L1 \| DISEASES 114548 \| NLRP3 \| DISEASES 2042 \| EPHA3 \| DISEASES 57142 \| RTN4 \| DISEASES 3363 \| HTR7 \| DISEASES 123283 \| TARSL2 \| DISEASES 23583 \| SMUG1 \| DISEASES 3117 \| HLA-DQA1 \| DISEASES 7060 \| THBS4 \| DISEASES 84545 \| MRPL43 \| DISEASES 3329 \| HSPD1 \| DISEASES 966 \| CD59 \| DISEASES 8805 \| TRIM24 \| DISEASES 4137 \| MAPT \| DISEASES 2963 \| GTF2F2 \| DISEASES 7137 \| TNNI3 \| DISEASES 6731 \| SRP72 \| DISEASES 51393 \| TRPV2 \| DISEASES 921 \| CD5 \| DISEASES 10277 \| UBE4B \| DISEASES 3146 \| HMGB1 \| DISEASES 9474 \| ATG5 \| DISEASES 4077 \| NBR1 \| DISEASES 7273 \| TTN \| DISEASES 3605 \| IL17A \| DISEASES 7332 \| UBE2L3 \| DISEASES 10617 \| STAMBP \| DISEASES 9045 \| RPL14 \| DISEASES 2624 \| GATA2 \| DISEASES 1861 \| TOR1A \| DISEASES 538 \| ATP7A \| DISEASES 2879 \| GPX4 \| DISEASES 9879 \| DDX46 \| DISEASES 3181 \| HNRNPA2B1 \| DISEASES 50618 \| ITSN2 \| DISEASES 4625 \| MYH7 \| DISEASES 3359 \| HTR3A \| DISEASES 355 \| FAS \| DISEASES 5265 \| SERPINA1 \| DISEASES 9260 \| PDLIM7 \| DISEASES 10438 \| C1D \| DISEASES 2961 \| GTF2E2 \| DISEASES 4624 \| MYH6 \| DISEASES 1108 \| CHD4 \| DISEASES 284119 \| PTRF \| DISEASES 60 \| ACTB \| DISEASES 6597 \| SMARCA4 \| DISEASES 51592 \| TRIM33 \| DISEASES 6775 \| STAT4 \| DISEASES 5699 \| PSMB10 \| DISEASES 7415 \| VCP \| DISEASES 9332 \| CD163 \| DISEASES 26191 \| PTPN22 \| DISEASES 4151 \| MB \| DISEASES 3123 \| HLA-DRB1 \| DISEASES 127343 \| DMBX1 \| DISEASES 6693 \| SPN \| DISEASES 170482 \| CLEC4C \| DISEASES 4311 \| MME \| DISEASES 1565 \| CYP2D6 \| DISEASES 54106 \| TLR9 \| DISEASES 26580 \| BSCL2 \| DISEASES 6533 \| SLC6A6 \| DISEASES 7169 \| TPM2 \| DISEASES 6772 \| STAT1 \| DISEASES 1312 \| COMT \| DISEASES 7150 \| TOP1 \| DISEASES 4283 \| CXCL9 \| DISEASES 1756 \| DMD \| DISEASES 8678 \| BECN1 \| DISEASES 7052 \| TGM2 \| DISEASES 22796 \| COG2 \| DISEASES 7139 \| TNNT2 \| DISEASES 5788 \| PTPRC \| DISEASES 6738 \| TROVE2 \| DISEASES 7402 \| UTRN \| DISEASES 2214 \| FCGR3A \| DISEASES 51744 \| CD244 \| DISEASES 2205 \| FCER1A \| DISEASES 911 \| CD1C \| DISEASES 632 \| BGLAP \| DISEASES 4582 \| MUC1 \| DISEASES 6280 \| S100A9 \| DISEASES 1520 \| CTSS \| DISEASES 80222 \| TARS2 \| DISEASES 5550 \| PREP \| DISEASES 5406 \| PNLIP \| DISEASES 914 \| CD2 \| DISEASES 1268 \| CNR1 \| DISEASES 4803 \| NGF \| DISEASES 2010 \| EMD \| DISEASES 284612 \| SYPL2 \| DISEASES 2332 \| FMR1 \| DISEASES 255631 \| COL24A1 \| DISEASES 959 \| CD40LG \| DISEASES 10555 \| AGPAT2 \| DISEASES 3434 \| IFIT1 \| DISEASES 3437 \| IFIT3 \| DISEASES 1757 \| SARDH \| DISEASES 6130 \| RPL7A \| DISEASES 7422 \| VEGFA \| DISEASES 958 \| CD40 \| DISEASES 6441 \| SFTPD \| DISEASES 10269 \| ZMPSTE24 \| DISEASES 10953 \| TOMM34 \| DISEASES 64102 \| TNMD \| DISEASES 23452 \| ANGPTL2 \| DISEASES 5928 \| RBBP4 \| DISEASES 2833 \| CXCR3 \| DISEASES 2934 \| GSN \| DISEASES 27293 \| SMPDL3B \| DISEASES 26190 \| FBXW2 \| DISEASES 7099 \| TLR4 \| DISEASES 24137 \| KIF4A \| DISEASES 3339 \| HSPG2 \| DISEASES 5535 \| PPP3R2 \| DISEASES 3108 \| HLA-DMA \| DISEASES 5698 \| PSMB9 \| DISEASES 5696 \| PSMB8 \| DISEASES 3118 \| HLA-DQA2 \| DISEASES 6048 \| RNF5 \| DISEASES 5081 \| PAX7 \| DISEASES 3304 \| HSPA1B \| DISEASES 10673 \| TNFSF13B \| DISEASES 50943 \| FOXP3 \| DISEASES 7133 \| TNFRSF1B \| DISEASES 1041 \| CDSN \| DISEASES 3105 \| HLA-A \| DISEASES 5394 \| EXOSC10 \| DISEASES 7056 \| THBD \| DISEASES 8718 \| TNFRSF25 \| DISEASES 57623 \| ZFAT \| DISEASES 152007 \| GLIPR2 \| DISEASES 441376 \| AARD \| DISEASES 51182 \| HSPA14 \| DISEASES 6354 \| CCL7 \| DISEASES 22929 \| SEPHS1 \| DISEASES 3356 \| HTR2A \| DISEASES 9636 \| ISG15 \| DISEASES 5621 \| PRNP \| DISEASES 5393 \| EXOSC9 \| DISEASES 1059 \| CENPB \| DISEASES 4712 \| NDUFB6 \| DISEASES 23586 \| DDX58 \| DISEASES 3559 \| IL2RA \| DISEASES 3456 \| IFNB1 \| DISEASES 140462 \| ASB9 \| DISEASES 51284 \| TLR7 \| DISEASES 11168 \| PSIP1 \| DISEASES 11172 \| INSL6 \| DISEASES 131405 \| TRIM71 \| DISEASES 339965 \| CCDC158 \| DISEASES 238 \| ALK \| DISEASES 8878 \| SQSTM1 \| DISEASES 7341 \| SUMO1 \| DISEASES 2591 \| GALNT3 \| DISEASES 12 \| SERPINA3 \| DISEASES 55601 \| DDX60 \| DISEASES 3885 \| KRT34 \| DISEASES 5627 \| PROS1 \| DISEASES 2962 \| GTF2F1 \| DISEASES 6355 \| CCL8 \| DISEASES 64400 \| AKTIP \| DISEASES 6696 \| SPP1 \| DISEASES 11273 \| ATXN2L \| DISEASES 79168 \| LILRA6 \| DISEASES 272 \| AMPD3 \| DISEASES 10020 \| GNE \| DISEASES 55234 \| SMU1 \| DISEASES 825 \| CAPN3 \| DISEASES 4703 \| NEB \| DISEASES 594857 \| NPS \| DISEASES 4599 \| MX1 \| DISEASES 3119 \| HLA-DQB1 \| DISEASES 7442 \| TRPV1 \| DISEASES 23515 \| MORC3 \| DISEASES 23308 \| ICOSLG \| DISEASES 79903 \| NAA60 \| DISEASES 6335 \| SCN9A \| DISEASES 81493 \| SYNC \| DISEASES 6295 \| SAG \| DISEASES 8291 \| DYSF \| DISEASES 9354 \| UBE4A \| DISEASES 50626 \| CYHR1 \| DISEASES 7311 \| UBA52 \| DISEASES 3120 \| HLA-DQB2 \| DISEASES 388552 \| BLOC1S3 \| DISEASES 4988 \| OPRM1 \| DISEASES 720 \| C4A \| DISEASES 7124 \| TNF \| DISEASES 3908 \| LAMA2 \| DISEASES 6635 \| SNRPE \| DISEASES 7072 \| TIA1 \| DISEASES 4615 \| MYD88 \| DISEASES 11155 \| LDB3 \| DISEASES 5334 \| PLCL1 \| DISEASES 388372 \| CCL4L1 \| DISEASES 5378 \| PMS1 \| DISEASES 548596 \| CKMT1A \| DISEASES 3115 \| HLA-DPB1 \| DISEASES 3920 \| LAMP2 \| DISEASES 63924 \| CIDEC \| DISEASES 834 \| CASP1 \| DISEASES 7555 \| CNBP \| DISEASES 3586 \| IL10 \| DISEASES 627 \| BDNF \| DISEASES 721 \| C4B \| DISEASES 389072 \| PLEKHM3 \| DISEASES 6168 \| RPL37A \| DISEASES 8801 \| SUCLG2 \| DISEASES 56244 \| BTNL2 \| DISEASES 30816 \| ERVW-1 \| DISEASES 51428 \| DDX41 \| DISEASES 3035 \| HARS \| DISEASES 114907 \| FBXO32 \| DISEASES 149466 \| C1orf210 \| DISEASES 270 \| AMPD1 \| DISEASES 3620 \| IDO1 \| DISEASES 23741 \| EID1 \| DISEASES 22827 \| PUF60 \| DISEASES 930 \| CD19 \| DISEASES 1232 \| CCR3 \| DISEASES 3684 \| ITGAM \| DISEASES 11331 \| PHB2 \| DISEASES 6999 \| TDO2 \| DISEASES 3227 \| HOXC11 \| DISEASES 8972 \| MGAM \| DISEASES 8742 \| TNFSF12 \| DISEASES 567 \| B2M \| DISEASES 820 \| CAMP \| DISEASES 8792 \| TNFRSF11A \| DISEASES 8677 \| STX10 \| DISEASES 54938 \| SARS2 \| DISEASES 6625 \| SNRNP70 \| DISEASES 102723508 \| KANTR \| DISEASES 79104 \| MEG8 \| DISEASES 4553 \| MT-TA \| DISEASES 6029 \| RN7SL1 \| DISEASES 619498 \| SNORD74 \| DISEASES
Locus	(Waiting for update.)

Disease ID	177
Disease	myositis
Integrated Phenotype	HPO \| Name(Total Integrated Phenotypes:2) HP:0003701 \| Proximal limb muscle weakness HP:0100614 \| Muscle inflammation
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:86) HP:0003201 \| Rhabdomyolysis \| 9 HP:0001324 \| Muscular weakness \| 6 HP:0006530 \| Interstitial lung disease \| 4 HP:0003560 \| Muscular dystrophy \| 4 HP:0012531 \| Pain \| 4 HP:0001370 \| Rheumatoid arthritis \| 4 HP:0001369 \| Arthritis \| 4 HP:0002725 \| Systemic lupus erythematosus \| 3 HP:0030880 \| Raynaud phenomenon \| 3 HP:0000602 \| Ophthalmoplegia \| 3 HP:0009071 \| Inflammatory myopathy \| 3 HP:0001945 \| Fever \| 3 HP:0003236 \| Elevated creatine kinase \| 2 HP:0001880 \| Eosinophilia \| 2 HP:0002015 \| Swallowing difficulty \| 2 HP:0030731 \| Carcinoma \| 2 HP:0012819 \| Myocarditis \| 2 HP:0002583 \| Colitis \| 2 HP:0007417 \| Discoid lupus erythematosus \| 2 HP:0001919 \| Acute renal failure \| 2 HP:0100280 \| Morbus Crohn \| 2 HP:0002090 \| Pneumonia \| 2 HP:0002669 \| Osteosarcoma \| 2 HP:0003198 \| Myopathic changes \| 2 HP:0000969 \| Dropsy \| 2 HP:0001909 \| Leukemia \| 2 HP:0100537 \| Inflammation of the fascia \| 2 HP:0100522 \| Thymoma \| 1 HP:0002960 \| Autoimmune condition \| 1 HP:0000544 \| CPEO \| 1 HP:0005584 \| Renal cell carcinoma \| 1 HP:0000083 \| Renal insufficiency \| 1 HP:0003003 \| Colon cancer \| 1 HP:0030664 \| Beevor's sign \| 1 HP:0001288 \| Gait disturbance \| 1 HP:0001701 \| Pericarditis \| 1 HP:0001635 \| Congestive heart failure \| 1 HP:0002894 \| Neoplasia of the pancreas \| 1 HP:0000211 \| Trismus \| 1 HP:0001824 \| Weight loss \| 1 HP:0045029 \| Eosinophilic fasciitis \| 1 HP:0000508 \| Drooping upper eyelid \| 1 HP:0003323 \| Muscle weakness, progressive \| 1 HP:0100242 \| Sarcoma \| 1 HP:0010783 \| Erythema \| 1 HP:0001639 \| Hypertrophic cardiomyopathy \| 1 HP:0100279 \| Ulcerative colitis \| 1 HP:0012115 \| Liver inflammation \| 1 HP:0003701 \| Proximal limb muscle weakness \| 1 HP:0003072 \| Hypercalcemia \| 1 HP:0012324 \| Myeloid leukemia \| 1 HP:0003689 \| Multiple mtDNA deletions \| 1 HP:0002633 \| Vasculitis \| 1 HP:0100324 \| Progressive systemic scleroderma \| 1 HP:0002036 \| Hiatus hernia \| 1 HP:0012378 \| Fatigue \| 1 HP:0000988 \| Exanthem \| 1 HP:0001907 \| Thromboembolic disease \| 1 HP:0001289 \| Confusion \| 1 HP:0000793 \| Membranoproliferative glomerulonephritis \| 1 HP:0100033 \| Tic disorder \| 1 HP:0003774 \| End-stage renal failure \| 1 HP:0005506 \| Chronic myeloid leukemia \| 1 HP:0002859 \| Rhabdomyosarcoma \| 1 HP:0004836 \| Acute promyelocytic leukemia \| 1 HP:0003326 \| Muscle pain \| 1 HP:0002608 \| Celiac disease \| 1 HP:0002527 \| Falls \| 1 HP:0011945 \| Cryptogenic organizing pneumonia \| 1 HP:0001298 \| Encephalopathy \| 1 HP:0000572 \| Visual loss \| 1 HP:0100614 \| Muscle inflammation \| 1 HP:0100533 \| Ocular inflammation \| 1 HP:0001349 \| Facial paresis, bilateral \| 1 HP:0007824 \| Total ophthalmoplegia \| 1 HP:0001371 \| Flexion contractures of joints \| 1 HP:0006744 \| Adrenal carcinoma \| 1 HP:0002273 \| Tetraparesis \| 1 HP:0002913 \| Myoglobinuria \| 1 HP:0000155 \| Oral ulcer \| 1 HP:0006466 \| Ankle contracture \| 1 HP:0001875 \| Neutropenia \| 1 HP:0000123 \| Nephritis \| 1 HP:0001873 \| Low platelet count \| 1 HP:0003202 \| Neurogenic muscle atrophy, especially in the lower limbs \| 1 HP:0012114 \| Endometrial carcinoma \| 1

Disease ID	177
Disease	myositis
Manually Symptom	UMLS \| Name(Total Manually Symptoms:20) C2707258 \| infections C2697391 \| rheumatoid arthritis C1962971 \| myocarditis C0748159 \| pulmonary involvement C0746787 \| neck cancer C0741885 \| occult malignancy C0410000 \| overlap syndrome C0206062 \| interstitial lung disease C0162323 \| polyarthritis C0152025 \| polyneuropathy C0085434 \| bacillary angiomatosis C0038013 \| ankylosing spondylitis C0035435 \| rheumatic diseases C0034372 \| quadriplegia C0027121 \| muscle inflammation C0026896 \| myasthenia gravis C0011849 \| diabetes mellitus C0011168 \| dysphagia C0009782 \| connective tissue disorder C0006663 \| calcinosis
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:7) C0410000 \| overlap syndrome \| 5 C0206062 \| interstitial lung disease \| 4 C0003873 \| rheumatoid arthritis \| 4 C0011168 \| dysphagia \| 2 C0027059 \| myocarditis \| 2 C0021311 \| infections \| 1 C0027121 \| muscle inflammation \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:17)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0027121	carbamazepine	D002220	298-46-4	myositis	MESH:D009220	marker/mechanism	8293614
C0027121	carbimazole	D002231	22232-54-8	myositis	MESH:D009220	marker/mechanism	1681385
C0027121	cisplatin	D002945	15663-27-1	myositis	MESH:D009220	marker/mechanism	10398795
C0027121	fluoxetine	D005473	54910-89-3	myositis	MESH:D009220	marker/mechanism	10868505
C0027121	griseofulvin	D006118	126-07-8	myositis	MESH:D009220	marker/mechanism	7572547
C0027121	hydroxyurea	D006918	127-07-1	myositis	MESH:D009220	marker/mechanism	12894095
C0027121	leuprolide	D016729	53714-56-0	myositis	MESH:D009220	marker/mechanism	1954704
C0027121	lidocaine	D008012	137-58-6	myositis	MESH:D009220	marker/mechanism	736396
C0027121	lovastatin	D008148	75330-75-5	myositis	MESH:D009220	marker/mechanism	16089017
C0027121	metformin	D008687	657-24-9	myositis	MESH:D009220	marker/mechanism	11062950
C0027121	phenytoin	D010672	57-41-0	myositis	MESH:D009220	marker/mechanism	1036571
C0027121	pravastatin	D017035	81093-37-0	myositis	MESH:D009220	marker/mechanism	12528328
C0027121	progesterone	D011374	57-83-0	myositis	MESH:D009220	marker/mechanism	3342908
C0027121	propylthiouracil	D011441	51-52-5	myositis	MESH:D009220	marker/mechanism	566489
C0027121	tacrolimus	D016559	109581-93-3	myositis	MESH:D009220	marker/mechanism	15110639
C0027121	tretinoin	D014212	302-79-4	myositis	MESH:D009220	marker/mechanism	10629576
C0027121	troglitazone	C057693	97322-87-7	myositis	MESH:D009220	marker/mechanism	11281188

FDA approved drug and dosage information(Total Drugs:1)
DiseaseID	Drug_name	active_ingredients	strength	Dosage Form/Route	Marketing Status	TE code	RLD	RS
MESH:D009220	mevacor	lovastatin	10MG Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons	TABLET;ORAL	Discontinued	None	Yes	No

FDA labeling changes(Total Drugs:1)
DiseaseID	Pediatric_Labeling_Date	Trade_Name	Generic_Name_or_Proper_Name	Indications Studied	Label Changes Summary	Product Labeling	BPCA(B)	PREA(P)	BPCA(B) and PREA(P)	Pediatric Rule (R)	Sponsor	Pediatric Exclusivity Granted Date	NNPS
MESH:D009220	02/14/2002	mevacor	lovastatin	Heterozygous Familial Hypercholesterolemia	New indication in adolescent boys and girls (at least one year post-menarche) 10-17 years of age	Labeling	B	-	-	-	Merck	07/17/2001	FALSE'

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