PedAM

Pediatric Disease Annotations & Medicines


	myelitis

Disease ID	780
Disease	myelitis
Definition	Inflammation of the spinal cord. Relatively common etiologies include infections; AUTOIMMUNE DISEASES; SPINAL CORD; and ischemia (see also SPINAL CORD VASCULAR DISEASES). Clinical features generally include weakness, sensory loss, localized pain, incontinence, and other signs of autonomic dysfunction.
Synonym	inflamm spinal cord inflammation of spinal cord inflammation, spinal cord inflammations, spinal cord inflammatory myelopathies inflammatory myelopathy myelitides myelitis (disorder) myelitis [disease/finding] myelitis, nos myelopathies, inflammatory myelopathy inflamm myelopathy, inflammatory spinal cord inflamm spinal cord inflammation spinal cord inflammations
DOID	DOID:322
UMLS	C0026975
MeSH	D009187
SNOMED-CT	SNOMEDCT_US_2016_09_01:41370002
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:59) C0024141 \| systemic lupus erythematosus \| 5 C0004943 \| behcet's disease \| 4 C0025289 \| meningitis \| 4 C0027873 \| neuromyelitis optica \| 4 C0030486 \| paraplegia \| 4 C0409974 \| lupus erythematosus \| 3 C0019158 \| hepatitis \| 3 C0026769 \| multiple sclerosis \| 3 C0032285 \| pneumonia \| 2 C1527336 \| sjogren's syndrome \| 2 C0014059 \| acute disseminated encephalomyelitis \| 2 C0270629 \| epidural abscess \| 2 C0021400 \| influenza \| 2 C0085273 \| parvovirus b19 infection \| 2 C0029134 \| optic neuritis \| 2 C0027813 \| neuritis \| 2 C0021053 \| immune disease \| 2 C1527336 \| sjogren syndrome \| 2 C0037928 \| myelopathy \| 2 C0002895 \| sickle cell anemia \| 2 C0040558 \| toxoplasmosis \| 2 C0014038 \| encephalitis \| 2 C0019196 \| hepatitis c \| 2 C0019196 \| viral hepatitis c \| 1 C0042769 \| viral infection \| 1 C0021053 \| immune disorders \| 1 C0025309 \| meningoencephalitis \| 1 C0154652 \| eosinophilic meningitis \| 1 C0040553 \| toxocariasis \| 1 C0026848 \| myopathy \| 1 C0036420 \| localized scleroderma \| 1 C0009241 \| cognitive disorders \| 1 C0011615 \| atopic dermatitis \| 1 C0042170 \| harada disease \| 1 C0042721 \| viral hepatitis \| 1 C0011303 \| demyelinating disease \| 1 C0003872 \| psoriatic arthritis \| 1 C0494491 \| mononeuropathy \| 1 C0042769 \| virus infection \| 1 C0024530 \| malaria \| 1 C0005697 \| neurogenic bladder \| 1 C0024198 \| lyme disease \| 1 C0021053 \| immune disorder \| 1 C0025290 \| aseptic meningitis \| 1 C0034372 \| tetraplegia \| 1 C0015230 \| rash \| 1 C1145670 \| respiratory failure \| 1 C0024537 \| vivax malaria \| 1 C0009447 \| common variable immunodeficiency \| 1 C0042170 \| vogt-koyanagi-harada disease \| 1 C0206141 \| idiopathic hypereosinophilic syndrome \| 1 C0003708 \| arachnoiditis \| 1 C0085278 \| antiphospholipid antibody syndrome \| 1 C0235025 \| motor neuropathy \| 1 C0206141 \| hypereosinophilic syndrome \| 1 C0011303 \| demyelinating diseases \| 1 C0011603 \| dermatitis \| 1 C0080178 \| spina bifida \| 1 C0085278 \| antiphospholipid syndrome \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:91) 5010 \| CLDN11 \| DISEASES 350 \| APOH \| DISEASES 7087 \| ICAM5 \| DISEASES 2639 \| GCDH \| DISEASES 1440 \| CSF3 \| DISEASES 3458 \| IFNG \| DISEASES 2026 \| ENO2 \| DISEASES 6431 \| SRSF6 \| DISEASES 2670 \| GFAP \| DISEASES 6737 \| TRIM21 \| DISEASES 2694 \| GIF \| DISEASES 29969 \| MDFIC \| DISEASES 3569 \| IL6 \| DISEASES 25833 \| POU2F3 \| DISEASES 10049 \| DNAJB6 \| DISEASES 60482 \| SLC5A7 \| DISEASES 10190 \| TXNDC9 \| DISEASES 3578 \| IL9 \| DISEASES 472 \| ATM \| DISEASES 10205 \| MPZL2 \| DISEASES 2895 \| GRID2 \| DISEASES 5903 \| RANBP2 \| DISEASES 9510 \| ADAMTS1 \| DISEASES 10563 \| CXCL13 \| DISEASES 56896 \| DPYSL5 \| DISEASES 6285 \| S100B \| DISEASES 178 \| AGL \| DISEASES 213 \| ALB \| DISEASES 4486 \| MST1R \| DISEASES 9607 \| CARTPT \| DISEASES 23582 \| CCNDBP1 \| DISEASES 1495 \| CTNNA1 \| DISEASES 5002 \| SLC22A18 \| DISEASES 23209 \| MLC1 \| DISEASES 358 \| AQP1 \| DISEASES 1776 \| DNASE1L3 \| DISEASES 7173 \| TPO \| DISEASES 7433 \| VIPR1 \| DISEASES 6656 \| SOX1 \| DISEASES 54584 \| GNB1L \| DISEASES 90249 \| UNC5A \| DISEASES 27445 \| PCLO \| DISEASES 5133 \| PDCD1 \| DISEASES 30850 \| CDR2L \| DISEASES 123228 \| SENP8 \| DISEASES 3605 \| IL17A \| DISEASES 50488 \| MINK1 \| DISEASES 273 \| AMPH \| DISEASES 617 \| BCS1L \| DISEASES 23607 \| CD2AP \| DISEASES 3123 \| HLA-DRB1 \| DISEASES 26047 \| CNTNAP2 \| DISEASES 5996 \| RGS1 \| DISEASES 115352 \| FCRL3 \| DISEASES 50624 \| CUZD1 \| DISEASES 959 \| CD40LG \| DISEASES 10673 \| TNFSF13B \| DISEASES 199 \| AIF1 \| DISEASES 7133 \| TNFRSF1B \| DISEASES 1041 \| CDSN \| DISEASES 4340 \| MOG \| DISEASES 1471 \| CST3 \| DISEASES 2550 \| GABBR1 \| DISEASES 3456 \| IFNB1 \| DISEASES 2618 \| GART \| DISEASES 51378 \| ANGPT4 \| DISEASES 4155 \| MBP \| DISEASES 2235 \| FECH \| DISEASES 361 \| AQP4 \| DISEASES 55576 \| STAB2 \| DISEASES 340152 \| ZC3H12D \| DISEASES 11202 \| KLK8 \| DISEASES 9244 \| CRLF1 \| DISEASES 2591 \| GALNT3 \| DISEASES 1267 \| CNP \| DISEASES 8091 \| HMGA2 \| DISEASES 1630 \| DCC \| DISEASES 7124 \| TNF \| DISEASES 84148 \| KAT8 \| DISEASES 3115 \| HLA-DPB1 \| DISEASES 6229 \| RPS24 \| DISEASES 5542 \| PRB1 \| DISEASES 51428 \| DDX41 \| DISEASES 9140 \| ATG12 \| DISEASES 137994 \| LETM2 \| DISEASES 10687 \| PNMA2 \| DISEASES 84107 \| ZIC4 \| DISEASES 930 \| CD19 \| DISEASES 23186 \| RCOR1 \| DISEASES 246734 \| NPCDR1 \| DISEASES 102723508 \| KANTR \| DISEASES
Locus	(Waiting for update.)

Disease ID	780
Disease	myelitis
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:32) HP:0002725 \| Systemic lupus erythematosus \| 4 HP:0002960 \| Autoimmune condition \| 4 HP:0001287 \| Meningitis \| 4 HP:0010550 \| Paraplegia \| 4 HP:0012115 \| Liver inflammation \| 3 HP:0012531 \| Pain \| 3 HP:0003447 \| Axonal loss \| 2 HP:0003470 \| Inability to move \| 2 HP:0002090 \| Pneumonia \| 2 HP:0003613 \| Antiphospholipid antibodies \| 2 HP:0002196 \| Myelopathy \| 2 HP:0002383 \| Encephalitis \| 2 HP:0000016 \| Urinary retention \| 2 HP:0100561 \| Spinal cord lesion \| 2 HP:0100653 \| Optic neuritis \| 2 HP:0002878 \| Respiratory failure \| 1 HP:0002540 \| Inability to walk \| 1 HP:0006562 \| Viral hepatitis \| 1 HP:0100310 \| Extradural hematoma \| 1 HP:0000011 \| Neurogenic bladder \| 1 HP:0002385 \| Paraparesis \| 1 HP:0002445 \| Paralysis of all four limbs \| 1 HP:0002414 \| Spina bifida \| 1 HP:0001880 \| Eosinophilia \| 1 HP:0009831 \| Single damaged nerve \| 1 HP:0200026 \| Ocular pain \| 1 HP:0009733 \| Glioma \| 1 HP:0001047 \| Atopic dermatitis \| 1 HP:0001907 \| Thromboembolic disease \| 1 HP:0006532 \| Pneumonia, recurrent episodes \| 1 HP:0000969 \| Dropsy \| 1 HP:0003198 \| Myopathic changes \| 1

Disease ID	780
Disease	myelitis
Manually Symptom	UMLS \| Name(Total Manually Symptoms:5) C2127436 \| ascending paralysis C1000483 \| anemia C0031117 \| peripheral neuropathy C0014038 \| encephalitis C0007459 \| neurogenic bladder
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:2) C0014038 \| encephalitis \| 2 C0005697 \| neurogenic bladder \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:3)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0026975	ethambutol	D004977	74-55-5	myelitis	MESH:D009187	marker/mechanism	4473301
C0026975	fosinopril	D017328	98048-97-6	myelitis	MESH:D009187	marker/mechanism	18769283
C0026975	methotrexate	D008727	1959/5/2	myelitis	MESH:D009187	marker/mechanism	11019787

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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