PedAM

Pediatric Disease Annotations & Medicines


	myasthenia gravis

Disease ID	9
Disease	myasthenia gravis
Definition	A disorder of neuromuscular transmission characterized by weakness of cranial and skeletal muscles. Autoantibodies directed against acetylcholine receptors damage the motor endplate portion of the NEUROMUSCULAR JUNCTION, impairing the transmission of impulses to skeletal muscles. Clinical manifestations may include diplopia, ptosis, and weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles. THYMOMA is commonly associated with this condition. (Adams et al., Principles of Neurology, 6th ed, p1459)
Synonym	erb-goldflam disease mg - myasthenia gravis myasthenia gravis (disorder) myasthenia gravis (mg) myasthenia gravis [disease/finding] myasthenia gravis disorder myasthenia gravis nos myasthenia gravis nos (disorder) myasthenia gravis, nos
Orphanet	ORPHANET:589
OMIM	OMIM:254200
DOID	DOID:437
UMLS	C0026896
MeSH	D009157
SNOMED-CT	SNOMEDCT_US_2016_09_01:91637004
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:115) C0040100 \| thymoma \| 55 C0040100 \| thymomas \| 7 C0409974 \| lupus erythematosus \| 6 C0278846 \| invasive thymoma \| 5 C0027059 \| myocarditis \| 5 C0242379 \| lung cancer \| 4 C0024141 \| systemic lupus erythematosus \| 4 C0030567 \| parkinson's disease \| 4 C1145670 \| respiratory failure \| 4 C0027873 \| neuromyelitis optica \| 3 C0014038 \| encephalitis \| 3 C0040128 \| thyroid disease \| 3 C0278848 \| recurrent thymoma \| 3 C1261473 \| sarcoma \| 3 C0040558 \| toxoplasmosis \| 2 C0023418 \| leukemia \| 2 C0012569 \| diplopia \| 2 C0019158 \| hepatitis \| 2 C0205969 \| malignant thymoma \| 2 C0037315 \| sleep-disordered breathing \| 2 C0035258 \| restless legs \| 2 C0020550 \| hyperthyroidism \| 2 C0005745 \| ptosis \| 2 C0021053 \| immune disorder \| 2 C0085655 \| polymyositis \| 2 C0035258 \| restless legs syndrome \| 2 C0002726 \| amyloidosis \| 2 C0241910 \| autoimmune hepatitis \| 1 C0042075 \| urological diseases \| 1 C1266091 \| spindle cell thymoma \| 1 C0007115 \| thyroid ca \| 1 C0029925 \| ovarian carcinoma \| 1 C0041296 \| tuberculosis \| 1 C0027765 \| neurological disease \| 1 C0024291 \| hemophagocytic lymphohistiocytosis \| 1 C0033975 \| psychosis \| 1 C0023473 \| chronic myeloid leukemia \| 1 C0085293 \| hepatitis e \| 1 C0002736 \| amyotrophic lateral sclerosis \| 1 C0566602 \| primary sclerosing cholangitis \| 1 C0242287 \| isaac's syndrome \| 1 C0520679 \| obstructive sleep apnea \| 1 C0751552 \| thymic cancer \| 1 C0206682 \| follicular thyroid carcinoma \| 1 C0684249 \| lung carcinoma \| 1 C0011633 \| dermatomyositis \| 1 C0018799 \| heart diseases \| 1 C0027868 \| neuromuscular disease \| 1 C0018021 \| goiter \| 1 C0851578 \| sleep disorders \| 1 C0023646 \| lichen planus \| 1 C0742472 \| cns lymphoma \| 1 C0598894 \| monocytic leukemia \| 1 C0002871 \| anaemia \| 1 C0085278 \| antiphospholipid syndrome \| 1 C0018916 \| hemangioma \| 1 C0029456 \| osteoporosis \| 1 C1140680 \| ovarian ca \| 1 C0007134 \| renal cell carcinoma \| 1 C0018920 \| cavernous hemangioma \| 1 C0684249 \| carcinoma of the lung \| 1 C0025164 \| megaesophagus \| 1 C0154143 \| toxic multinodular goiter \| 1 C0008313 \| sclerosing cholangitis \| 1 C0011847 \| diabetes \| 1 C0004623 \| bacterial disease \| 1 C0042164 \| uveitis \| 1 C0042165 \| anterior uveitis \| 1 C0003467 \| anxiety \| 1 C0037052 \| sick sinus syndrome \| 1 C0040128 \| thyroid disorders \| 1 C0042870 \| vitamin d deficiency \| 1 C0029089 \| ophthalmoplegia \| 1 C0035412 \| rhabdomyosarcoma \| 1 C0021053 \| immune disorders \| 1 C0004096 \| asthma \| 1 C0393819 \| chronic inflammatory demyelinating polyneuropathy \| 1 C0035258 \| restless legs syndrome (rls) \| 1 C0042870 \| vitamin d defic \| 1 C0019069 \| hemophilia \| 1 C0021053 \| immune disease \| 1 C0036341 \| schizophrenia \| 1 C0011849 \| diabetes mellitus \| 1 C0036220 \| kaposi sarcoma \| 1 C0032914 \| preeclampsia \| 1 C0008312 \| biliary cirrhosis \| 1 C0549473 \| thyroid carcinoma \| 1 C0036202 \| sarcoidosis \| 1 C0003873 \| rheumatoid arthritis \| 1 C0085436 \| cryptococcal meningitis \| 1 C0008311 \| cholangitis \| 1 C0030442 \| bulbar palsy \| 1 C0878544 \| cardiomyopathy \| 1 C0011603 \| dermatitis \| 1 C0008728 \| churg-strauss syndrome \| 1 C0042900 \| vitiligo \| 1 C0022972 \| lambert-eaton myasthenic syndrome \| 1 C0025289 \| meningitis \| 1 C0024530 \| malaria \| 1 C0018799 \| heart disease \| 1 C0205969 \| thymic carcinoma \| 1 C0022972 \| myasthenic syndrome \| 1 C0042109 \| urticaria \| 1 C0033860 \| psoriasis \| 1 C0152013 \| adenocarcinoma of the lung \| 1 C0005747 \| blepharospasm \| 1 C0029134 \| optic neuritis \| 1 C0152134 \| internuclear ophthalmoplegia \| 1 C0037315 \| sleep apnea \| 1 C0008312 \| primary biliary cirrhosis \| 1 C0001403 \| addison's disease \| 1 C0026848 \| muscle disease \| 1 C0018024 \| retrosternal goiter \| 1 C0027813 \| neuritis \| 1 C0023470 \| myeloid leukemia \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:9) POMC \| 5443 \| CTD_human FAS \| 355 \| CTD_human HLA-DPB1 \| 3115 \| CTD_human MUSK \| 4593 \| CTD_human HLA-B \| 3106 \| CTD_human TNIP1 \| 10318 \| GWASCAT TNFRSF11A \| 8792 \| GWASCAT PTPN22 \| 26191 \| GWASCAT CFB \| 629 \| CTD_human
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:31) 5243 \| ABCB1 \| infer 1636 \| ACE \| infer 348 \| APOE \| infer 729230 \| CCR2 \| infer 1234 \| CCR5 \| infer 1144 \| CHRND \| infer 1145 \| CHRNE \| infer 4261 \| CIITA \| infer 1493 \| CTLA4 \| infer 1565 \| CYP2D6 \| infer 2212 \| FCGR2A \| infer 2214 \| FCGR3A \| infer 2215 \| FCGR3B \| infer 3105 \| HLA-A \| infer 3106 \| HLA-B \| infer 3107 \| HLA-C \| infer 3117 \| HLA-DQA1 \| infer 3119 \| HLA-DQB1 \| infer 3122 \| HLA-DRA \| infer 3123 \| HLA-DRB1 \| infer 3458 \| IFNG \| infer 3586 \| IL10 \| infer 3592 \| IL12A \| infer 3593 \| IL12B \| infer 3552 \| IL1A \| infer 3560 \| IL2RB \| infer 3956 \| LGALS1 \| infer 4049 \| LTA \| infer 2908 \| NR3C1 \| infer 26191 \| PTPN22 \| infer 7124 \| TNF \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:245) 920 \| CD4 \| DISEASES 608 \| TNFRSF17 \| DISEASES 79931 \| TNIP3 \| DISEASES 23152 \| CIC \| DISEASES 23645 \| PPP1R15A \| DISEASES 10423 \| CDIPT \| DISEASES 7038 \| TG \| DISEASES 8797 \| TNFRSF10A \| DISEASES 5971 \| RELB \| DISEASES 973 \| CD79A \| DISEASES 5949 \| RBP3 \| DISEASES 3558 \| IL2 \| DISEASES 969 \| CD69 \| DISEASES 4618 \| MYF6 \| DISEASES 3458 \| IFNG \| DISEASES 3820 \| KLRB1 \| DISEASES 10279 \| PRSS16 \| DISEASES 3565 \| IL4 \| DISEASES 604 \| BCL6 \| DISEASES 22924 \| MAPRE3 \| DISEASES 7128 \| TNFAIP3 \| DISEASES 2703 \| GJA8 \| DISEASES 2700 \| GJA3 \| DISEASES 4656 \| MYOG \| DISEASES 1271 \| CNTFR \| DISEASES 11017 \| SNRNP27 \| DISEASES 51081 \| MRPS7 \| DISEASES 718 \| C3 \| DISEASES 11034 \| DSTN \| DISEASES 1236 \| CCR7 \| DISEASES 4974 \| OMG \| DISEASES 4654 \| MYOD1 \| DISEASES 8735 \| MYH13 \| DISEASES 7837 \| PXDN \| DISEASES 9253 \| NUMBL \| DISEASES 9590 \| AKAP12 \| DISEASES 182 \| JAG1 \| DISEASES 56923 \| NMUR2 \| DISEASES 6341 \| SCO1 \| DISEASES 4064 \| CD180 \| DISEASES 271 \| AMPD2 \| DISEASES 1828 \| DSG1 \| DISEASES 1144 \| CHRND \| DISEASES 3569 \| IL6 \| DISEASES 4836 \| NMT1 \| DISEASES 3442 \| IFNA5 \| DISEASES 6366 \| CCL21 \| DISEASES 6741 \| SSB \| DISEASES 1134 \| CHRNA1 \| DISEASES 6857 \| SYT1 \| DISEASES 55068 \| ENOX1 \| DISEASES 5264 \| PHYH \| DISEASES 3553 \| IL1B \| DISEASES 55717 \| WDR11 \| DISEASES 3574 \| IL7 \| DISEASES 26511 \| CHIC2 \| DISEASES 941 \| CD80 \| DISEASES 590 \| BCHE \| DISEASES 8506 \| CNTNAP1 \| DISEASES 5443 \| POMC \| DISEASES 3383 \| ICAM1 \| DISEASES 80321 \| CEP70 \| DISEASES 29999 \| FSCN3 \| DISEASES 5286 \| PIK3C2A \| DISEASES 10180 \| RBM6 \| DISEASES 939 \| CD27 \| DISEASES 7112 \| TMPO \| DISEASES 8826 \| IQGAP1 \| DISEASES 3687 \| ITGAX \| DISEASES 1039 \| CDR2 \| DISEASES 8795 \| TNFRSF10B \| DISEASES 340419 \| RSPO2 \| DISEASES 3439 \| IFNA1 \| DISEASES 740 \| MRPL49 \| DISEASES 3606 \| IL18 \| DISEASES 7292 \| TNFSF4 \| DISEASES 2895 \| GRID2 \| DISEASES 925 \| CD8A \| DISEASES 5506 \| PPP1R3A \| DISEASES 761 \| CA3 \| DISEASES 10563 \| CXCL13 \| DISEASES 56896 \| DPYSL5 \| DISEASES 56683 \| C21orf59 \| DISEASES 115650 \| TNFRSF13C \| DISEASES 326 \| AIRE \| DISEASES 643 \| CXCR5 \| DISEASES 1145 \| CHRNE \| DISEASES 2215 \| FCGR3B \| DISEASES 2560 \| GABRB1 \| DISEASES 213 \| ALB \| DISEASES 51151 \| SLC45A2 \| DISEASES 7098 \| TLR3 \| DISEASES 27242 \| TNFRSF21 \| DISEASES 1437 \| CSF2 \| DISEASES 7253 \| TSHR \| DISEASES 5913 \| RAPSN \| DISEASES 6786 \| STIM1 \| DISEASES 43 \| ACHE \| DISEASES 1493 \| CTLA4 \| DISEASES 1140 \| CHRNB1 \| DISEASES 154 \| ADRB2 \| DISEASES 3575 \| IL7R \| DISEASES 23261 \| CAMTA1 \| DISEASES 27087 \| B3GAT1 \| DISEASES 27289 \| RND1 \| DISEASES 25992 \| SNED1 \| DISEASES 5222 \| PGA5 \| DISEASES 4179 \| CD46 \| DISEASES 9495 \| AKAP5 \| DISEASES 4261 \| CIITA \| DISEASES 1604 \| CD55 \| DISEASES 10318 \| TNIP1 \| DISEASES 4684 \| NCAM1 \| DISEASES 80381 \| CD276 \| DISEASES 643834 \| PGA3 \| DISEASES 940 \| CD28 \| DISEASES 8784 \| TNFRSF18 \| DISEASES 3739 \| KCNA4 \| DISEASES 6900 \| CNTN2 \| DISEASES 942 \| CD86 \| DISEASES 90249 \| UNC5A \| DISEASES 5133 \| PDCD1 \| DISEASES 135 \| ADORA2A \| DISEASES 4221 \| MEN1 \| DISEASES 10011 \| SRA1 \| DISEASES 8165 \| AKAP1 \| DISEASES 50615 \| IL21R \| DISEASES 3117 \| HLA-DQA1 \| DISEASES 3329 \| HSPD1 \| DISEASES 966 \| CD59 \| DISEASES 859 \| CAV3 \| DISEASES 921 \| CD5 \| DISEASES 7273 \| TTN \| DISEASES 3605 \| IL17A \| DISEASES 285489 \| DOK7 \| DISEASES 84940 \| CORO6 \| DISEASES 1861 \| TOR1A \| DISEASES 1798 \| DPAGT1 \| DISEASES 51322 \| WAC \| DISEASES 2213 \| FCGR2B \| DISEASES 6261 \| RYR1 \| DISEASES 26191 \| PTPN22 \| DISEASES 4151 \| MB \| DISEASES 10092 \| ARPC5 \| DISEASES 3123 \| HLA-DRB1 \| DISEASES 7037 \| TFRC \| DISEASES 170482 \| CLEC4C \| DISEASES 2107 \| ETF1 \| DISEASES 23085 \| ERC1 \| DISEASES 676 \| BRDT \| DISEASES 26047 \| CNTNAP2 \| DISEASES 9542 \| NRG2 \| DISEASES 1756 \| DMD \| DISEASES 2987 \| GUK1 \| DISEASES 1378 \| CR1 \| DISEASES 1380 \| CR2 \| DISEASES 6993 \| DYNLT1 \| DISEASES 5788 \| PTPRC \| DISEASES 7402 \| UTRN \| DISEASES 356 \| FASLG \| DISEASES 2214 \| FCGR3A \| DISEASES 912 \| CD1D \| DISEASES 4580 \| MTX1 \| DISEASES 7062 \| TCHH \| DISEASES 4942 \| OAT \| DISEASES 79626 \| TNFAIP8L2 \| DISEASES 8349 \| HIST2H2BE \| DISEASES 914 \| CD2 \| DISEASES 965 \| CD58 \| DISEASES 1137 \| CHRNA4 \| DISEASES 959 \| CD40LG \| DISEASES 1791 \| DNTT \| DISEASES 774 \| CACNA1B \| DISEASES 9211 \| LGI1 \| DISEASES 958 \| CD40 \| DISEASES 2833 \| CXCR3 \| DISEASES 7099 \| TLR4 \| DISEASES 1043 \| CD52 \| DISEASES 4593 \| MUSK \| DISEASES 3339 \| HSPG2 \| DISEASES 3118 \| HLA-DQA2 \| DISEASES 3376 \| IARS \| DISEASES 10673 \| TNFSF13B \| DISEASES 50943 \| FOXP3 \| DISEASES 7133 \| TNFRSF1B \| DISEASES 2017 \| CTTN \| DISEASES 3105 \| HLA-A \| DISEASES 4340 \| MOG \| DISEASES 8718 \| TNFRSF25 \| DISEASES 6520 \| SLC3A2 \| DISEASES 643847 \| PGA4 \| DISEASES 4038 \| LRP4 \| DISEASES 7293 \| TNFRSF4 \| DISEASES 375790 \| AGRN \| DISEASES 146 \| ADRA1D \| DISEASES 7222 \| TRPC3 \| DISEASES 3456 \| IFNB1 \| DISEASES 6606 \| SMN1 \| DISEASES 6607 \| SMN2 \| DISEASES 51378 \| ANGPT4 \| DISEASES 4155 \| MBP \| DISEASES 361 \| AQP4 \| DISEASES 8292 \| COLQ \| DISEASES 1146 \| CHRNG \| DISEASES 4099 \| MAG \| DISEASES 51347 \| TAOK3 \| DISEASES 64400 \| AKTIP \| DISEASES 145957 \| NRG4 \| DISEASES 174 \| AFP \| DISEASES 56666 \| PANX2 \| DISEASES 54704 \| PDP1 \| DISEASES 346562 \| GNAT3 \| DISEASES 3119 \| HLA-DQB1 \| DISEASES 54890 \| ALKBH5 \| DISEASES 7441 \| VPREB1 \| DISEASES 55777 \| MBD5 \| DISEASES 3267 \| AGFG1 \| DISEASES 65986 \| ZBTB10 \| DISEASES 10321 \| CRISP3 \| DISEASES 3120 \| HLA-DQB2 \| DISEASES 3718 \| JAK3 \| DISEASES 81542 \| TMX1 \| DISEASES 6329 \| SCN4A \| DISEASES 720 \| C4A \| DISEASES 7124 \| TNF \| DISEASES 3106 \| HLA-B \| DISEASES 5817 \| PVR \| DISEASES 4049 \| LTA \| DISEASES 84148 \| KAT8 \| DISEASES 3115 \| HLA-DPB1 \| DISEASES 3612 \| IMPA1 \| DISEASES 3586 \| IL10 \| DISEASES 54475 \| NLE1 \| DISEASES 5682 \| PSMA1 \| DISEASES 721 \| C4B \| DISEASES 27333 \| GOLIM4 \| DISEASES 57541 \| ZNF398 \| DISEASES 25816 \| TNFAIP8 \| DISEASES 51428 \| DDX41 \| DISEASES 270 \| AMPD1 \| DISEASES 930 \| CD19 \| DISEASES 820 \| CAMP \| DISEASES 100302692 \| FTX \| DISEASES 10255 \| HCG9 \| DISEASES 102723508 \| KANTR \| DISEASES
Locus	(Waiting for update.)

Disease ID	9
Disease	myasthenia gravis
Integrated Phenotype	HPO \| Name(Total Integrated Phenotypes:28) HP:0000872 \| Hashimoto thyroiditis HP:0001324 \| Muscle weakness HP:0002015 \| Dysphagia HP:0001283 \| Bulbar palsy HP:0030210 \| Muscle specific kinase antibody positivity HP:0001878 \| Hemolytic anemia HP:0012410 \| Pure red cell aplasia HP:0100614 \| Myositis HP:0001250 \| Seizures HP:0000508 \| Ptosis HP:0000365 \| Hearing impairment HP:0001260 \| Dysarthria HP:0002094 \| Dyspnea HP:0000836 \| Hyperthyroidism HP:0000709 \| Psychosis HP:0001063 \| Acrocyanosis HP:0010780 \| Hyperacusis HP:0000651 \| Diplopia HP:0000597 \| Ophthalmoparesis HP:0030006 \| Single fiber EMG abnormality HP:0008207 \| Primary adrenal insufficiency HP:0012115 \| Hepatitis HP:0003076 \| Glycosuria HP:0002725 \| Systemic lupus erythematosus HP:0001370 \| Rheumatoid arthritis HP:0030208 \| Acetylcholine receptor antibody positivity HP:0000777 \| Abnormality of the thymus HP:0003401 \| Paresthesia
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:83) HP:0100522 \| Thymoma \| 54 HP:0030210 \| Anti-MUSK antibodies \| 7 HP:0012378 \| Fatigue \| 6 HP:0002960 \| Autoimmune condition \| 5 HP:0012819 \| Myocarditis \| 5 HP:0002878 \| Respiratory failure \| 4 HP:0002725 \| Systemic lupus erythematosus \| 4 HP:0000508 \| Drooping upper eyelid \| 4 HP:0100242 \| Sarcoma \| 3 HP:0000820 \| Thyroid abnormality \| 3 HP:0002383 \| Encephalitis \| 3 HP:0012531 \| Pain \| 2 HP:0012452 \| Restless legs \| 2 HP:0030731 \| Carcinoma \| 2 HP:0011034 \| Amyloid disease \| 2 HP:0001283 \| Bulbar palsies \| 2 HP:0012115 \| Liver inflammation \| 2 HP:0000651 \| Diplopia \| 2 HP:0001324 \| Muscular weakness \| 2 HP:0002015 \| Swallowing difficulty \| 2 HP:0001909 \| Leukemia \| 2 HP:0000836 \| Overactive thyroid \| 2 HP:0005584 \| Renal cell carcinoma \| 1 HP:0000544 \| CPEO \| 1 HP:0001048 \| Cavernous angioma \| 1 HP:0001260 \| Dysarthric speech \| 1 HP:0011704 \| Sick sinus syndrome \| 1 HP:0003765 \| Psoriasis \| 1 HP:0001300 \| Parkinsonism \| 1 HP:0030773 \| Internuclear ophthalmoplegia \| 1 HP:0000853 \| Goitre \| 1 HP:0007417 \| Discoid lupus erythematosus \| 1 HP:0001607 \| Subglottic stenosis \| 1 HP:0000939 \| Osteoporosis \| 1 HP:0000554 \| Uveitis \| 1 HP:0000819 \| Diabetes mellitus \| 1 HP:0001696 \| Situs inversus totalis \| 1 HP:0100512 \| Vitamin D deficiency \| 1 HP:0000709 \| Psychosis \| 1 HP:0001045 \| Blotchy loss of skin color \| 1 HP:0008207 \| Addison's disease \| 1 HP:0000739 \| Anxiety \| 1 HP:0001025 \| Hives \| 1 HP:0010516 \| Enlarged thymus \| 1 HP:0030151 \| Cholangitis \| 1 HP:0010535 \| Sleep apnea \| 1 HP:0001287 \| Meningitis \| 1 HP:0000708 \| Behavioral problems \| 1 HP:0100785 \| Insomnia \| 1 HP:0100602 \| Pre-eclampsia \| 1 HP:0002870 \| Obstructive sleep apnea \| 1 HP:0001903 \| Anemia \| 1 HP:0001488 \| Bilateral ptosis \| 1 HP:0200119 \| Acute liver inflammation \| 1 HP:0002827 \| Hip dislocation \| 1 HP:0000597 \| Ophthalmoparesis \| 1 HP:0001638 \| Cardiomyopathy \| 1 HP:0006731 \| Follicular thyroid carcinoma \| 1 HP:0012325 \| Chronic myelomonocytic leukemia \| 1 HP:0100753 \| Schizophrenia \| 1 HP:0001028 \| Strawberry mark \| 1 HP:0030069 \| Primary central nervous system lymphoma \| 1 HP:0012122 \| Anterior uveitis \| 1 HP:0002613 \| Biliary cirrhosis \| 1 HP:0100543 \| Cognitive deficits \| 1 HP:0100595 \| Camptocormia \| 1 HP:0000602 \| Ophthalmoplegia \| 1 HP:0030049 \| Brain abscess \| 1 HP:0011069 \| Extra teeth \| 1 HP:0002315 \| Headaches \| 1 HP:0002099 \| Asthma \| 1 HP:0002104 \| Absence of spontaneous respiration \| 1 HP:0005506 \| Chronic myeloid leukemia \| 1 HP:0002380 \| Muscle twitch \| 1 HP:0002720 \| Decreased immunoglobulin A \| 1 HP:0003324 \| Muscle weakness, diffuse \| 1 HP:0002890 \| Thyroid carcinoma \| 1 HP:0100653 \| Optic neuritis \| 1 HP:0007354 \| Amyotrophic lateral sclerosis \| 1 HP:0000643 \| Spontaneous closure of eyelid \| 1 HP:0012324 \| Myeloid leukemia \| 1 HP:0002859 \| Rhabdomyosarcoma \| 1 HP:0000738 \| Sensory hallucination \| 1

Disease ID	9
Disease	myasthenia gravis
Manually Symptom	UMLS \| Name(Total Manually Symptoms:171) C2712340 \| dyspnoea C2700565 \| pancreatic cancer C2697391 \| rheumatoid arthritis C2697310 \| sarcoidosis C2598155 \| pain C2364133 \| infection C2364118 \| weakness C2364114 \| tremor C2364051 \| fatigue C2237120 \| near vision C1963211 \| pericarditis C1963179 \| nausea C1963064 \| anxiety C1963059 \| adrenal insufficiency C1962971 \| myocarditis C1848814 \| thymic neoplasia C1707516 \| corneal sensitivity C1660219 \| analgesia C1521999 \| acute myocardial infarction C1521736 \| parkinson's disease C1420725 \| thymoma C1417325 \| multiple sclerosis C1406941 \| thymitis C1373218 \| immunosuppression C1336744 \| thymolipoma C1336082 \| squamous cell carcinoma of the thymus C1335363 \| parotid gland mucoepidermoid carcinoma C1322286 \| thymic carcinoma C1321756 \| achalasia C1278533 \| disorder of neuromuscular transmission C1266101 \| thymic epithelial tumor C1266091 \| medullary thymoma C1262091 \| lymphocytic infiltration C1261473 \| sarcoma C1145670 \| respiratory failure C1142517 \| lupus anticoagulant C1136085 \| monoclonal gammapathy C1000483 \| anemia C0920350 \| autoimmune thyroiditis C0878544 \| myocardial disorder C0877781 \| unilateral headache C0751576 \| vocal cord paresis C0746869 \| neuromuscular weakness C0700502 \| primary hypothyroidism C0700323 \| neuromuscular blockade C0700323 \| neuromuscular block C0700323 \| muscle relaxation C0699893 \| carcinoma of the skin C0392674 \| exhaustion C0349644 \| testicular lymphoma C0349453 \| thyroid mass C0346935 \| conjunctival kaposi's sarcoma C0341265 \| jejunal diverticulosis C0333997 \| lymphoid hyperplasia C0278848 \| recurrent thymoma C0278846 \| invasive thymoma C0271446 \| nonsuppurative otitis media C0264492 \| chronic respiratory failure C0264490 \| acute respiratory failure C0263449 \| perioral dermatitis C0242647 \| mucosa-associated lymphoid tissue lymphoma C0242584 \| autoimmune thrombocytopenia C0242287 \| isaacs' syndrome C0241910 \| autoimmune hepatitis C0241700 \| voice fatigue C0240318 \| mediastinal mass C0239182 \| watery diarrhea C0235031 \| neurological symptoms C0234665 \| lid retraction C0234665 \| eyelid retraction C0234132 \| pyramidal signs C0231230 \| fatigability C0206061 \| interstitial pneumonitis C0205969 \| thymic carcinomas C0205969 \| malignant thymoma C0178468 \| autoimmune thyroid disease C0162670 \| mitochondrial myopathy C0162538 \| selective iga deficiency C0155338 \| total ophthalmoplegia C0154199 \| thymus disorders C0152134 \| internuclear ophthalmoplegia C0152116 \| spasmodic torticollis C0086367 \| resistant ovary syndrome C0086132 \| symptoms of depression C0085786 \| fibrosing alveolitis C0085655 \| polymyositis C0085278 \| antiphospholipid syndrome C0085215 \| premature ovarian failure C0042928 \| vocal cord paralysis C0042900 \| vitiligo C0042769 \| virus infection C0042454 \| velopharyngeal incompetence C0040156 \| thyrotoxicosis C0040147 \| thyroiditis C0040128 \| thyroid disorders C0040116 \| thymus tumors C0040116 \| thymus tumor C0040116 \| thymus neoplasms C0040116 \| thymic tumors C0040116 \| thymic tumor C0040100 \| thymomas C0039070 \| syncope C0038454 \| strokes C0038454 \| cerebral infarction C0037315 \| sleep apnea syndrome C0037315 \| sleep apnea C0035435 \| rheumatic diseases C0035229 \| respiratory insufficiency C0034902 \| pure red cell aplasia C0034155 \| thrombotic thrombocytopenic purpura C0034069 \| pulmonary fibrosis C0033377 \| ptosis C0032000 \| pituitary adenoma C0031511 \| phaeochromocytoma C0030920 \| peptic ulcer C0030552 \| muscle pareses C0030472 \| paraneoplastic syndrome C0029166 \| oral manifestations C0028866 \| 3rd nerve palsy C0027873 \| neuromyelitis optica C0027830 \| neurofibromas C0027726 \| nephrotic syndrome C0027121 \| myositis C0027121 \| inflammatory myopathy C0026976 \| transverse myelitis C0026846 \| muscular atrophy C0026846 \| muscle atrophy C0025164 \| megaoesophagus C0024141 \| systemic lupus erythematosus C0023524 \| progressive multifocal leukoencephalopathy C0023473 \| chronic myeloid leukemia C0023434 \| chronic lymphatic leukaemia C0023066 \| laryngeal stridor C0022876 \| premature labor C0021933 \| intussusception C0020550 \| hyperthyroidism C0020541 \| portal hypertension C0019080 \| hemorrhage C0018799 \| heart disease C0018552 \| hamartoma C0018213 \| graves' disease C0018024 \| retrosternal goiter C0017661 \| iga nephropathy C0017658 \| glomerulonephritis C0017531 \| castleman's disease C0015310 \| exotropia C0014038 \| encephalitis C0013592 \| ectropion C0011860 \| diabetes C0011849 \| diabetes mellitus C0011608 \| dermatitis herpetiformis C0011303 \| demyelinating disease C0011302 \| cns demyelinating disease C0011168 \| dysphagia C0009766 \| allergic conjunctivitis C0008728 \| churg-strauss syndrome C0006105 \| brain abscess C0005747 \| blepharospasm C0004364 \| autoimmune disorders C0004364 \| autoimmune diseases C0004364 \| autoimmune disease C0004245 \| atrioventricular conduction block C0004096 \| asthma C0003864 \| arthritis C0003469 \| anxiety disorders C0002991 \| dermatofibromas C0002880 \| autoimmune hemolytic anemia C0002171 \| alopecia areata C0001418 \| adenocarcinoma C0001403 \| addison's disease C0001396 \| stokes-adams attacks
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:50) C0040100 \| thymoma \| 54 C0004093 \| weakness \| 10 C0015672 \| fatigue \| 6 C0027059 \| myocarditis \| 5 C0017531 \| castleman's disease \| 5 C0278846 \| invasive thymoma \| 5 C0040100 \| thymomas \| 4 C1145670 \| respiratory failure \| 4 C0024141 \| systemic lupus erythematosus \| 4 C0234119 \| neuromuscular blockade \| 4 C0030567 \| parkinson's disease \| 4 C0027873 \| neuromyelitis optica \| 3 C0014038 \| encephalitis \| 3 C1261473 \| sarcoma \| 3 C0009450 \| infection \| 3 C0240318 \| mediastinal mass \| 2 C0021079 \| immunosuppression \| 2 C0005745 \| ptosis \| 2 C0030193 \| pain \| 2 C0278848 \| recurrent thymoma \| 2 C1848814 \| thymic neoplasia \| 2 C0085655 \| polymyositis \| 2 C0011168 \| dysphagia \| 2 C0234119 \| neuromuscular block \| 2 C0020550 \| hyperthyroidism \| 2 C0178468 \| autoimmune thyroid disease \| 2 C0205969 \| malignant thymoma \| 2 C0008728 \| churg-strauss syndrome \| 1 C0085278 \| antiphospholipid syndrome \| 1 C0152134 \| internuclear ophthalmoplegia \| 1 C0037315 \| sleep apnea \| 1 C0205969 \| thymic carcinoma \| 1 C0005747 \| blepharospasm \| 1 C0001403 \| addison's disease \| 1 C0004364 \| autoimmune disorders \| 1 C0042900 \| vitiligo \| 1 C0003467 \| anxiety \| 1 C0018024 \| retrosternal goiter \| 1 C0231230 \| fatigability \| 1 C0040128 \| thyroid disorders \| 1 C0235031 \| neurological symptoms \| 1 C0011847 \| diabetes \| 1 C0333997 \| lymphoid hyperplasia \| 1 C0006105 \| brain abscess \| 1 C0023473 \| chronic myeloid leukemia \| 1 C0018799 \| heart disease \| 1 C0004096 \| asthma \| 1 C0004364 \| autoimmune diseases \| 1 C0011849 \| diabetes mellitus \| 1 C0241910 \| autoimmune hepatitis \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:9)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs2476601	25119822	27335	EIF3K	umls:C0026896	BeFree	DNA samples from 416 patients with clinically diagnosed generalized MG (231 with Abs to acetylcholine receptor, AChR-MG), 53 with Abs to muscle-specific kinase (MuSK-MG), 55 patients with no detectable Abs (SN-MG), 77 patients with thymoma (TAMG) and 293 healthy controls (HC) were genotyped for the SNP (PTPN22 R620W, C1858T, rs2476601).	0.004614512	2014	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2476601	19406179	26191	PTPN22	umls:C0026896	BeFree	The autoimmunity-related polymorphism PTPN22 1858C/T is associated with anti-titin antibody-positive myasthenia gravis.	0.129815515	2009	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2476601	18533277	26191	PTPN22	umls:C0026896	BeFree	PTPN22 R620W promotes production of anti-AChR autoantibodies and IL-2 in myasthenia gravis.	0.129815515	2008	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2476601	23055271	26191	PTPN22	umls:C0026896	GWASCAT	Risk for myasthenia gravis maps to a (151) Pro→Ala change in TNIP1 and to human leukocyte antigen-B*08.	0.129815515	2012	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2476601	19406179	7273	TTN	umls:C0026896	BeFree	The autoimmunity-related polymorphism PTPN22 1858C/T is associated with anti-titin antibody-positive myasthenia gravis.	0.003257302	2009	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2476601	18533277	3558	IL2	umls:C0026896	BeFree	PTPN22 R620W promotes production of anti-AChR autoantibodies and IL-2 in myasthenia gravis.	0.000814326	2008	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2476601	25119822	26191	PTPN22	umls:C0026896	BeFree	The association of PTPN22 R620W polymorphism is stronger with late-onset AChR-myasthenia gravis in Turkey.	0.129815515	2014	PTPN22;AP4B1-AS1	1	113834946	A	G
rs4263037	25643325	8792	TNFRSF11A	umls:C0026896	GWASCAT	A genome-wide association study of myasthenia gravis.	0.12	2015	TNFRSF11A	18	62349000	G	A
rs4958881	23055271	10318	TNIP1	umls:C0026896	GWASCAT	Risk for myasthenia gravis maps to a (151) Pro→Ala change in TNIP1 and to human leukocyte antigen-B*08.	0.120542884	2012	TNIP1	5	151070675	T	C

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:255)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
1	5548512	rs9786944	G	A	rs9786944	23055271	4.20E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
1	6572175	rs3935435	G	A	rs3935435	23055271	1.10E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
1	32336098	rs671101	A	G	rs671101	23055271	1.70E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
1	53114736	rs706497	T	C	rs706497	23055271	4.70E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
1	62342230	rs6685516	T	C	rs6685516	23055271	4.80E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
1	64534922	rs1260773	G	A	rs1260773	23055271	2.00E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
1	111262340	rs4839556	G	A	rs4839556	23055271	3.60E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
1	111322419	rs1999511	C	A	rs1999511	23055271	6.60E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
1	114233871	rs4839335	G	A	rs4839335	23055271	3.20E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
1	114253639	rs1230647	C	T	rs1230647	23055271	3.80E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
1	114330202	rs2797409	T	C	rs2797409	23055271	2.60E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
1	114377568	rs2476601	A	G	rs2476601	23055271	8.00E-10	NA	1.71	[1.44-2.02]	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	rs2476601-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G,C
1	114393748	rs1217407	A	G	rs1217407	23055271	2.40E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
1	114420462	rs7529353	G	A	rs7529353	23055271	4.80E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
1	115677183	rs2078371	T	C	rs2078371	23055271	1.80E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
1	163313880	rs17362993	G	A	rs17362993	23055271	1.70E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
1	173353881	rs1557121	T	C	rs1557121	23055271	7.70E-06	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
1	225902582	rs12044217	C	T	rs12044217	23055271	4.00E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
1	228903818	rs728370	C	T	rs728370	23055271	2.60E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
1	228916634	rs241324	A	G	rs241324	23055271	2.80E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
1	232505285	rs644690	T	C	rs644690	23055271	4.40E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
2	24739410	rs1545255	A	G	rs1545255	23055271	3.70E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
2	43999182	rs725238	C	T	rs725238	23055271	3.70E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
2	43999734	rs3762571	T	G	rs3762571	23055271	3.30E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
2	44974370	rs12473962	C	A	rs12473962	23055271	3.50E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
2	58999505	rs10204566	G	A	rs10204566	23055271	1.00E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
2	59036916	rs6719884	A	C	rs6719884	23055271	3.00E-06	NA	1.35	[1.19-1.53]	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	rs6850606-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
2	62551472	rs10865331	A	G	rs10865331	23055271	4.50E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
2	73407076	rs2043092	C	T	rs2043092	23055271	1.30E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
2	107784393	rs1029864	T	C	rs1029864	23055271	1.20E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
2	107790491	rs2079917	C	T	rs2079917	23055271	3.60E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
2	130603995	rs7421552	A	G	rs7421552	23055271	2.40E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
2	173841435	rs1026290	G	A	rs1026290	23055271	4.60E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
2	191973563	rs6752770	A	G	rs6752770	23055271	4.20E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
2	198950240	rs1064213	G	A	rs1064213	23055271	1.60E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	14886796	rs1389300	A	G	rs1389300	23055271	4.90E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	24686548	rs9843745	G	A,T	rs9843745	23055271	1.90E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	24691022	rs7610415	C	T	rs7610415	23055271	4.60E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	24705221	rs9812637	G	A	rs9812637	23055271	1.90E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	24718439	rs6550889	G	T	rs6550889	23055271	2.50E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	117640199	rs6805565	C	A	rs6805565	23055271	1.40E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
3	122942782	rs12487554	G	A	rs12487554	23055271	8.50E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	123019763	rs3934729	T	C	rs3934729	23055271	2.80E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	124382676	rs231601	A	G	rs231601	23055271	9.60E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
3	135310068	rs6808137	G	A	rs6808137	23055271	1.50E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
3	156102890	rs940050	T	C	rs940050	23055271	4.30E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	166749739	rs10460872	T	C	rs10460872	23055271	2.30E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
3	170659019	rs10936665	T	G	rs10936665	23055271	1.10E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
4	11352031	rs917684	A	G	rs917684	23055271	2.80E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
4	42838348	rs1562840	T	C	rs1562840	23055271	3.80E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
4	42864696	rs6850606	G	A	rs6850606	23055271	3.10E-06	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
4	42865108	rs10012449	C	A	rs10012449	23055271	5.70E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
4	69646009	rs11726899	T	C	rs11726899	23055271	6.40E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
4	71007047	rs2272040	A	G	rs2272040	23055271	2.90E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
4	101210715	rs4235450	C	T	rs4235450	23055271	4.30E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
4	107828001	rs427983	T	C	rs427983	23055271	3.30E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
4	183751029	rs4862110	T	C	rs4862110	23055271	1.70E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	23493956	rs10075972	C	T	rs10075972	23055271	3.80E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	37849688	rs1862573	G	A	rs1862573	23055271	1.10E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	51737413	rs1113266	T	C	rs1113266	23055271	4.80E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
5	52642056	rs37787	A	G	rs37787	23055271	4.80E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	55424472	rs318791	A	G	rs318791	23055271	4.50E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	58337481	rs1353747	T	G	rs1353747	23055271	4.50E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
5	118064125	rs7727675	G	A	rs7727675	23055271	8.60E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
5	122354892	rs982926	G	A	rs982926	23055271	3.20E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
5	131526190	rs156031	A	G	rs156031	23055271	1.90E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
5	133422816	rs244689	A	G	rs244689	23055271	6.90E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	133446575	rs756699	C	T	rs756699	23055271	2.40E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
5	133845112	rs6877546	T	C	rs6877546	23055271	4.20E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
5	133847179	rs1860059	C	T	rs1860059	23055271	1.40E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	150425467	rs2233299	G	A	rs2233299	23055271	2.10E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	150438988	rs1422673	C	T	rs1422673	23055271	6.20E-09	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
5	150440097	rs2233287	G	A	rs2233287	23055271	4.60E-09	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	150450236	rs4958881	T	C	rs4958881	23055271	3.00E-10	NA	1.73	[1.46-2.06]	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	rs4958881-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	150451650	rs3792785	T	C	rs3792785	23055271	3.60E-08	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
5	150455732	rs3792783	A	G	rs3792783	23055271	1.70E-08	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	150462638	rs13168551	T	C	rs13168551	23055271	6.00E-06	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	159879978	rs2431697	T	C	rs2431697	23055271	1.40E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	168391557	rs1432910	T	C	rs1432910	23055271	3.00E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
6	15523101	rs1047631	T	C	rs1047631	23055271	2.50E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
6	15658212	rs1474605	T	C	rs1474605	23055271	5.40E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
6	29537224	rs1235162	A	G	rs1235162	23055271	1.80E-49	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
6	29899677	rs2524005	G	A	rs2524005	23055271	3.50E-51	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	29945949	rs3132685	G	A,C,T	rs3132685	23055271	1.00E-54	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	30032522	rs8321	A	C	rs8321	23055271	6.50E-57	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
6	30038647	rs9261290	T	C	rs9261290	23055271	2.60E-58	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
6	30078275	rs2523989	C	T	rs2523989	23055271	1.10E-57	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
6	30079993	rs2523987	A	C	rs2523987	23055271	8.70E-61	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
6	30080274	rs2517598	G	A	rs2517598	23055271	1.40E-55	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
6	30279130	rs3130380	G	A	rs3130380	23055271	1.80E-62	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
6	30327839	rs3130350	G	T	rs3130350	23055271	3.40E-63	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
6	30333505	rs3094054	G	T	rs3094054	23055271	1.90E-61	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	30544401	rs3132610	A	G	rs3132610	23055271	2.80E-63	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
6	30782002	rs886424	C	T	rs886424	23055271	4.10E-69	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
6	30824532	rs2844659	C	T	rs2844659	23055271	1.30E-68	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
6	30829522	rs2844657	A	G	rs2844657	23055271	3.00E-69	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
6	30893941	rs4678	G	A	rs4678	23055271	4.60E-68	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	30920124	rs3132580	G	A	rs3132580	23055271	1.90E-70	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	30933794	rs3095089	G	T	rs3095089	23055271	1.80E-79	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	30957618	rs886403	T	C	rs886403	23055271	4.60E-60	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
6	30972865	rs1634718	A	G	rs1634718	23055271	8.20E-61	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
6	31058340	rs3130544	C	A	rs3130544	23055271	2.00E-90	NA	5.64	[4.77-6.67]	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	rs3130544-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	31081205	rs2233956	T	C	rs2233956	23055271	6.10E-68	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
6	31101674	rs3130564	C	T	rs3130564	23055271	1.60E-56	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	31129310	rs7750641	C	T	rs7750641	23055271	1.20E-92	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	31140047	rs1265159	G	A	rs1265159	23055271	1.40E-57	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	31145920	rs887464	C	T	rs887464	23055271	2.50E-52	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
6	31199208	rs3130473	C	T	rs3130473	23055271	1.50E-55	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	NA
6	31355318	rs2596560	T	C	rs2596560	23055271	3.10E-58	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
6	31448976	rs3099844	C	A	rs3099844	23055271	4.70E-85	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	NA
6	31472720	rs2855812	G	T	rs2855812	23055271	4.20E-52	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	NA
6	31481105	rs2516400	G	A	rs2516400	23055271	8.40E-53	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	31568469	rs2857595	G	A	rs2857595	23055271	1.00E-60	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	31601843	rs3115663	T	C	rs3115663	23055271	2.40E-67	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
6	31603770	rs11229	A	G	rs11229	23055271	3.80E-67	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
6	31632134	rs3130618	C	A	rs3130618	23055271	2.00E-67	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	31721033	rs3131379	G	A	rs3131379	23055271	9.70E-84	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	31870326	rs558702	G	A	rs558702	23055271	5.20E-82	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	31918860	rs1270942	A	G	rs1270942	23055271	1.20E-79	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
6	31940897	rs389884	A	G	rs389884	23055271	1.80E-79	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
6	32161430	rs204990	C	A	rs204990	23055271	7.00E-49	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
6	32172993	rs3131296	C	T	rs3131296	23055271	7.10E-61	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
6	32261252	rs7775397	T	G	rs7775397	23055271	2.60E-75	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
6	32336766	rs3129939	A	G	rs3129939	23055271	1.10E-49	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
6	32363215	rs1980493	T	C	rs1980493	23055271	5.90E-70	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
6	32380208	rs3129963	A	G	rs3129963	23055271	2.50E-64	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
6	32392877	rs3135353	C	T	rs3135353	23055271	1.80E-72	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
6	32414273	rs3129890	T	C	rs3129890	23055271	3.40E-51	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	NA
6	32605884	rs2187668	C	T	rs2187668	23055271	1.30E-67	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
6	32666526	rs1794282	C	T	rs1794282	23055271	1.40E-73	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
6	32755290	rs7762279	T	C	rs7762279	23055271	1.60E-58	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
7	50320726	rs1026421	T	C	rs1026421	23055271	4.40E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
7	115327840	rs10267413	T	C	rs10267413	23055271	4.40E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
7	115362547	rs6466555	A	G	rs6466555	23055271	4.20E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
7	115374142	rs10245192	A	G	rs10245192	23055271	4.50E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
7	115375732	rs6946417	T	C	rs6946417	23055271	4.40E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
7	127912566	rs4731437	T	C	rs4731437	23055271	1.00E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
7	127915376	rs1466146	G	A	rs1466146	23055271	2.10E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
7	127916208	rs6979784	G	A	rs6979784	23055271	2.10E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
7	128568960	rs729302	A	C	rs729302	23055271	2.30E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
7	128573967	rs4728142	G	A	rs4728142	23055271	3.60E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G,A
7	128594183	rs10488631	T	C	rs10488631	23055271	4.00E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
7	138638846	rs661079	G	A	rs661079	23055271	4.00E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
7	150525879	rs4725367	T	C	rs4725367	23055271	6.50E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
7	150539151	rs6956432	A	G	rs6956432	23055271	2.00E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
7	156708467	rs2969123	T	C	rs2969123	23055271	4.90E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
7	156722842	rs7791257	C	T	rs7791257	23055271	2.70E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
8	14307817	rs11989070	T	G	rs11989070	23055271	3.10E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
8	39862881	rs10109853	C	T	rs10109853	23055271	3.60E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
8	39867827	rs10958579	G	A	rs10958579	23055271	4.70E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
8	41591274	rs17661532	G	A	rs17661532	23055271	2.00E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
8	58265798	rs12679553	T	C	rs12679553	23055271	1.20E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
8	59900712	rs7813241	T	C	rs7813241	23055271	3.90E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
8	63898146	rs4737623	A	G	rs4737623	23055271	1.80E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
8	63906828	rs1031553	G	A	rs1031553	23055271	2.20E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
8	104290148	rs6990501	A	G	rs6990501	23055271	1.90E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
8	125688407	rs3915792	A	G	rs3915792	23055271	1.80E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
8	140010100	rs951920	G	A	rs951920	23055271	1.10E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
9	11117514	rs2382267	C	T	rs2382267	23055271	3.90E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
9	12947238	rs10756426	T	A,C	rs10756426	23055271	3.00E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
9	80257000	rs10869950	C	T	rs10869950	23055271	3.80E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
9	87744810	rs1078815	G	A	rs1078815	23055271	4.60E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
9	87761907	rs10868257	C	T	rs10868257	23055271	3.80E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
9	87778956	rs620420	C	T	rs620420	23055271	3.40E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
9	89372790	rs2274561	A	G	rs2274561	23055271	2.20E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
9	111545688	rs4978738	G	A	rs4978738	23055271	4.80E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
9	131772389	rs3750340	T	G	rs3750340	23055271	3.20E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
10	64487073	rs224149	T	C	rs224149	23055271	2.70E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
10	64516306	rs10761660	T	C	rs10761660	23055271	2.90E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
10	68824793	rs10509279	C	T	rs10509279	23055271	4.70E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
10	101291593	rs11190140	T	C	rs11190140	23055271	4.40E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
10	118238417	rs10787677	C	A	rs10787677	23055271	3.70E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
10	118278528	rs10787704	G	A	rs10787704	23055271	3.30E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
11	99101320	rs7947162	A	G	rs7947162	23055271	3.50E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
11	128266238	rs7939722	A	C	rs7939722	23055271	4.70E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
11	128269844	rs7934171	C	A	rs7934171	23055271	2.00E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
11	129267481	rs752450	G	A	rs752450	23055271	2.70E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
12	3439051	rs1860394	C	A	rs1860394	23055271	4.40E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
12	3451273	rs10848856	A	G	rs10848856	23055271	2.70E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
12	5555120	rs10849271	G	A	rs10849271	23055271	8.90E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
12	40732394	rs1427271	T	C	rs1427271	23055271	1.10E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
12	95289731	rs1434239	T	C	rs1434239	23055271	4.30E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
12	95296558	rs6538566	A	C	rs6538566	23055271	1.20E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
12	109091089	rs10746129	T	C	rs10746129	23055271	1.60E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
12	114802361	rs1946295	A	G	rs1946295	23055271	4.40E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
12	116188095	rs780876	T	C	rs780876	23055271	2.00E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
13	91085354	rs9515742	G	A	rs9515742	23055271	1.90E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
14	34022139	rs2210054	G	A	rs2210054	23055271	3.70E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
14	44039374	rs7146515	G	A	rs7146515	23055271	2.90E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
14	44179054	rs2038532	C	T	rs2038532	23055271	1.00E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C,T
14	44193257	rs9323081	G	A	rs9323081	23055271	1.30E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
14	44207575	rs17309078	G	A	rs17309078	23055271	2.80E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
14	98788406	rs7148865	G	T	rs7148865	23055271	1.40E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
14	98815286	rs7152787	T	C	rs7152787	23055271	4.80E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
14	103234562	rs8008676	C	T	rs8008676	23055271	4.10E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
14	103304425	rs7143963	C	T	rs7143963	23055271	1.70E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
14	103342049	rs1131877	T	C	rs1131877	23055271	2.10E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
14	103362017	rs4906269	A	C	rs4906269	23055271	2.20E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
14	103377321	rs10133111	G	A	rs10133111	23055271	1.70E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
15	31463378	rs7169523	G	A	rs7169523	23055271	2.00E-06	NA	1.4	[1.22-1.60]	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	rs7169523-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
15	32274157	rs11636101	C	A	rs11636101	23055271	3.00E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
15	32296373	rs2063722	C	A	rs2063722	23055271	1.20E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
15	34901430	rs16954263	G	A	rs16954263	23055271	3.50E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
15	40700022	rs10518693	C	T	rs10518693	23055271	1.90E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
15	40717302	rs2034650	G	A	rs2034650	23055271	3.20E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
15	60791954	rs2290430	A	C	rs2290430	23055271	4.30E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
15	61289944	rs10519096	G	A	rs10519096	23055271	9.20E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
15	61290188	rs10519097	C	T	rs10519097	23055271	4.70E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
15	66513813	rs4776292	T	C	rs4776292	23055271	1.30E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
15	75289722	rs3812945	T	C	rs3812945	23055271	4.60E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
15	75382542	rs12148488	G	T	rs12148488	23055271	3.80E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G,T
15	77314974	rs4420499	G	T	rs4420499	23055271	3.60E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
16	15168760	rs4985147	T	C	rs4985147	23055271	2.40E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
16	70818759	rs2271047	A	G	rs2271047	23055271	4.80E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
16	70818759	rs34544582	A	AG	rs2271047	23055271	4.80E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
16	85620902	rs6540278	C	T	rs6540278	23055271	2.90E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
16	86666303	rs9925302	C	T	rs9925302	23055271	3.60E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
17	37814080	rs1877031	G	A	rs1877031	23055271	3.00E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
17	37817482	rs2271308	T	C	rs2271308	23055271	2.90E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
17	37821435	rs113612868	G	GT	rs931992	23055271	4.90E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
17	37821435	rs931992	G	T	rs931992	23055271	4.90E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
17	37922259	rs907092	G	A	rs907092	23055271	4.40E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
17	37976469	rs9303277	C	T	rs9303277	23055271	1.50E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
17	38028634	rs11557467	G	T	rs11557467	23055271	6.00E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
17	38051348	rs8067378	A	G	rs8067378	23055271	2.70E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
17	38066240	rs2290400	T	C	rs2290400	23055271	3.80E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
17	38069949	rs7216389	C	T	rs7216389	23055271	1.20E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
17	70902716	rs7502006	C	T	rs7502006	23055271	4.50E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
17	70915599	rs6501581	G	A	rs6501581	23055271	3.10E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
18	43660400	rs3745004	C	A	rs3745004	23055271	7.20E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
18	49291961	rs323092	A	G	rs323092	23055271	3.50E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
18	67535184	rs1790588	T	C	rs1790588	23055271	4.90E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
18	74936640	rs9956473	T	C	rs9956473	23055271	2.10E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
18	75118412	rs12456229	C	A	rs12456229	23055271	5.50E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
18	75127574	rs6565965	T	C	rs6565965	23055271	1.20E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
18	77266154	rs8099113	G	A	rs8099113	23055271	4.20E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
19	10616303	rs11668429	T	G	rs11668429	23055271	4.00E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
19	23073205	rs8111895	G	A	rs8111895	23055271	2.10E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
19	56970750	rs4801321	A	G	rs4801321	23055271	1.40E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
19	56981382	rs3760848	T	C	rs3760848	23055271	4.30E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
19	57145434	rs1548866	C	T	rs1548866	23055271	4.80E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
20	4092860	rs4813669	A	G	rs4813669	23055271	1.10E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
20	4764682	rs2422979	T	C	rs2422979	23055271	1.60E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
20	17591579	rs11698138	A	G	rs11698138	23055271	1.60E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
20	38661339	rs6028806	C	T	rs6028806	23055271	4.50E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
20	47727341	rs6066968	A	G	rs6066968	23055271	3.50E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
22	27730109	rs572159	A	G	rs572159	23055271	9.10E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
22	34759241	rs470049	G	A	rs470049	23055271	4.80E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
X	40792395	rs5963897	C	T	rs5963897	23055271	4.40E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
X	68844248	rs5936708	A	G	rs5936708	23055271	3.10E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
X	68856453	rs1327347	A	G	rs1327347	23055271	3.60E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
X	100163068	rs5921691	C	A	rs5921691	23055271	1.10E-05	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
X	100188535	rs1204413	T	C	rs1204413	23055271	2.30E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
X	140376888	rs845188	T	C	rs845188	23055271	1.40E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
X	149676274	rs497220	A	G	rs497220	23055271	1.90E-04	NA	NA	NA	400 European ancestry cases; 5,505 European ancestry controls	European(5905)	ALL(5905)	EUR(5905)	ALL(5905)	Myasthenia gravis	HPOID:0001290	Generalized hypotonia	DOID:437	myasthenia gravis	NA	NA	EFOID:0000540	immune system disease	Myasthenia Gravis	NA	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C

Mapped by lexical matching(Total Items:1)
HP ID	HP Name	MP ID	MP Name	Annotation
HP:0001890	Autoimmune hemolytic anemia	MP:0001577	anemia;HP:0002893	Pituitary adenoma

Mapped by homologous gene(Total Items:1)
HP ID	HP Name	MP ID	MP Name	Annotation
HP:0001890	Autoimmune hemolytic anemia	MP:0002420	abnormal adaptive immunity;HP:0000100	Nephrotic syndrome

Chemical(Total Drugs:18)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0026896	atropine	D001285	51-55-8	myasthenia gravis	MESH:D009157	therapeutic	4739612
C0026896	azithromycin	D017963	83905-01-5	myasthenia gravis	MESH:D009157	marker/mechanism	19587486
C0026896	busulfan	D002066	55-98-1	myasthenia gravis	MESH:D009157	marker/mechanism	119414
C0026896	chloroquine	D002738	1954/5/7	myasthenia gravis	MESH:D009157	marker/mechanism	10612109
C0026896	cyclosporine	D016572	59865-13-3	myasthenia gravis	MESH:D009157	therapeutic	17199845
C0026896	erythromycin	D004917	114-07-8	myasthenia gravis	MESH:D009157	marker/mechanism	8701248
C0026896	hydroxocobalamin	D006879	13422-51-0	myasthenia gravis	MESH:D009157	therapeutic	17098697
C0026896	levonorgestrel	D016912	797-63-7	myasthenia gravis	MESH:D009157	marker/mechanism	7491061
C0026896	ofloxacin	D015242	82419-36-1	myasthenia gravis	MESH:D009157	marker/mechanism	16858118
C0026896	peginterferon alfa-2b	C417083	-	myasthenia gravis	MESH:D009157	marker/mechanism	17934275
C0026896	phenytoin	D010672	57-41-0	myasthenia gravis	MESH:D009157	marker/mechanism	9046861
C0026896	pravastatin	D017035	81093-37-0	myasthenia gravis	MESH:D009157	marker/mechanism	16609346
C0026896	ribavirin	D012254	36791-04-5	myasthenia gravis	MESH:D009157	marker/mechanism	19581773
C0026896	ribavirin	D012254	36791-04-5	myasthenia gravis	MESH:D009157	therapeutic	17934275
C0026896	ritonavir	D019438	-	myasthenia gravis	MESH:D009157	marker/mechanism	9572258
C0026896	tacrolimus	D016559	109581-93-3	myasthenia gravis	MESH:D009157	therapeutic	15883336
C0026896	trihexyphenidyl	D014282	144-11-6	myasthenia gravis	MESH:D009157	marker/mechanism	3033545
C0026896	trimethadione	D014293	127-48-0	myasthenia gravis	MESH:D009157	marker/mechanism	4987393

FDA approved drug and dosage information(Total Drugs:7)
DiseaseID	Drug_name	active_ingredients	strength	Dosage Form/Route	Marketing Status	TE code	RLD	RS
MESH:D009157	busulfex	busulfan	6MG/ML	INJECTABLE;INJECTION	Prescription	AP	Yes	Yes
MESH:D009157	norvir	ritonavir	80MG/ML	SOLUTION;ORAL	Prescription	None	Yes	Yes
MESH:D009157	norvir	ritonavir	100MG	CAPSULE;ORAL	Discontinued	None	No	No
MESH:D009157	norvir	ritonavir	100MG	CAPSULE;ORAL	Prescription	None	Yes	Yes
MESH:D009157	norvir	ritonavir	100MG	TABLET;ORAL	Prescription	AB	Yes	Yes
MESH:D009157	mirena	levonorgestrel	52MG	INTRAUTERINE DEVICE;INTRAUTERINE	Prescription	None	Yes	Yes
MESH:D009157	levonorgestrel	levonorgestrel	75MG/IMPLANT	IMPLANT;IMPLANTATION	Discontinued	None	No	No

FDA labeling changes(Total Drugs:7)
DiseaseID	Pediatric_Labeling_Date	Trade_Name	Generic_Name_or_Proper_Name	Indications Studied	Label Changes Summary	Product Labeling	BPCA(B)	PREA(P)	BPCA(B) and PREA(P)	Pediatric Rule (R)	Sponsor	Pediatric Exclusivity Granted Date	NNPS
MESH:D009157	01/13/2003	busulfex	busulfan	Part of a conditioning regimen administered prior to hematopoietic progenitor cell transplantation for a variety of malignant hematologic or non-malignant diseases	The population pharmacokinetic estimates of busulfan for clearance and volume of distribution were determined in an open-label, uncontrolled PK study in 24 pediatric patients 5 months to 16 years who received busulfan as part of a conditioning regimen administered prior to hematopoietic progenitor cell transplantation for a variety of malignant hematologic or non-malignant diseases Suggested dosing regimen	Labeling	B	-	-	-	Orphan Medical	12/3/2002	FALSE'
MESH:D009157	6/10/2005	norvir	ritonavir	Treatment of HIV-infection in combination with other antiretroviral agents	Extended age range from 2 years down to 1 month AE profile in the pediatric population was similar to that for adults Information on dose and PK parameters	Labeling	B	-	-	-	Abbott	06/14/2005	FALSE'
MESH:D009157	6/10/2005	norvir	ritonavir	Treatment of HIV-infection in combination with other antiretroviral agents	Extended age range from 2 years down to 1 month AE profile in the pediatric population was similar to that for adults Information on dose and PK parameters	Labeling	B	-	-	-	Abbott	06/14/2005	FALSE'
MESH:D009157	6/10/2005	norvir	ritonavir	Treatment of HIV-infection in combination with other antiretroviral agents	Extended age range from 2 years down to 1 month AE profile in the pediatric population was similar to that for adults Information on dose and PK parameters	Labeling	B	-	-	-	Abbott	06/14/2005	FALSE'
MESH:D009157	6/10/2005	norvir	ritonavir	Treatment of HIV-infection in combination with other antiretroviral agents	Extended age range from 2 years down to 1 month AE profile in the pediatric population was similar to that for adults Information on dose and PK parameters	Labeling	B	-	-	-	Abbott	06/14/2005	FALSE'
MESH:D009157	1/10/2009	mirena	levonorgestrel-releasing intrauterine system	Treatment of heavy menstrual bleeding for women using intrauterine contraception	New indication for the treatment of heavy menstrual bleeding for women who choose to use intrauterine contraception Use before menarche is not indicated	Labeling	-	P	-	-	Berlex	-	TRUE'
MESH:D009157	10/7/2009	plan b one step	levonorgestrel	Emergency contraception - OTC in women 17 years and older; RX for women younger than age 17 years	New single dose 1.5 mg tablet New dosage regimen	Labeling	-	P	-	-	Duramed	-	FALSE'