PedAM

Pediatric Disease Annotations & Medicines


	multiple sclerosis

Disease ID	280
Disease	multiple sclerosis
Definition	An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
Synonym	disseminated sclerosis ds - disseminated sclerosis generalised multiple sclerosis generalized multiple sclerosis generalized multiple sclerosis (disorder) insular sclerosis ms (multiple sclerosis) ms - multiple sclerosis ms multiple sclerosis multiple sclerosis (disorder) multiple sclerosis (ms) multiple sclerosis - ms multiple sclerosis [disease/finding] multiple sclerosis ms multiple sclerosis nos multiple sclerosis nos (disorder) multiple sclerosis, nos multiples sclerosis sclerosis multiple sclerosis, disseminated sclerosis, insular sclerosis, multiple
OMIM	OMIM:126200
DOID	DOID:2377
ICD10	ICD10CM:G35
UMLS	C0026769
MeSH	D009103
SNOMED-CT	SNOMEDCT_US_2016_09_01:192928003;SNOMEDCT_US_2016_09_01:24700007
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:227) C0014070 \| encephalomyelitis \| 56 C0011570 \| depression \| 55 C0029134 \| optic neuritis \| 39 C0027813 \| neuritis \| 36 C0042485 \| venous insufficiency \| 32 C0023524 \| progressive multifocal leukoencephalopathy \| 22 C0270612 \| leukoencephalopathy \| 20 C0679466 \| cognitive deficits \| 16 C0040997 \| trigeminal neuralgia \| 14 C0851578 \| sleep disorders \| 14 C0033953 \| sexual dysfunction \| 12 C0042164 \| uveitis \| 12 C0003467 \| anxiety \| 12 C0014038 \| encephalitis \| 8 C0028738 \| nystagmus \| 8 C0021053 \| immune disease \| 7 C0019158 \| hepatitis \| 7 C0042166 \| intermediate uveitis \| 6 C0497327 \| dementia \| 6 C0037315 \| sleep apnea \| 6 C0037317 \| sleep disturbance \| 5 C0027873 \| neuromyelitis optica \| 5 C0149931 \| migraine \| 5 C0027765 \| neurological disease \| 5 C0035258 \| restless legs syndrome \| 5 C0005697 \| neurogenic bladder \| 5 C0014544 \| epilepsy \| 5 C0042384 \| vasculitis \| 4 C0011303 \| demyelinating disease \| 4 C0041696 \| major depression \| 4 C0003864 \| arthritis \| 4 C0520679 \| obstructive sleep apnea \| 4 C0033860 \| psoriasis \| 4 C0037317 \| sleep disturbances \| 4 C0242350 \| erectile dysfunction \| 3 C0002871 \| anemia \| 3 C0026975 \| myelitis \| 3 C0029089 \| ophthalmoplegia \| 3 C0004134 \| ataxia \| 3 C0029456 \| osteoporosis \| 3 C0042075 \| urological diseases \| 3 C0241910 \| autoimmune hepatitis \| 3 C0008049 \| varicella \| 3 C0027765 \| neurological disorders \| 3 C0027765 \| neurological disorder \| 3 C0033975 \| psychosis \| 3 C0030805 \| bullous pemphigoid \| 3 C0042075 \| urological disorders \| 3 C0019360 \| zoster \| 3 C0009241 \| cognitive disorders \| 3 C0042373 \| vascular disease \| 3 C0005586 \| bipolar disorder \| 2 C0035258 \| restless legs \| 2 C0014544 \| epileptic seizures \| 2 C0442874 \| neuropathy \| 2 C0021400 \| influenza \| 2 C0003469 \| anxiety disorders \| 2 C0152177 \| trigeminal neuropathy \| 2 C0017601 \| glaucoma \| 2 C0042769 \| virus infection \| 2 C0025309 \| meningoencephalitis \| 2 C0033953 \| sexual disorders \| 2 C0751967 \| relapsing-remitting multiple sclerosis \| 2 C0003469 \| anxiety disorder \| 2 C1527336 \| sjogren's syndrome \| 2 C0079731 \| b-cell lymphoma \| 2 C0024299 \| lymphoma \| 2 C0030805 \| pemphigoid \| 2 C0035078 \| renal failure \| 2 C0007570 \| celiac disease \| 2 C0027051 \| myocardial infarction \| 2 C0271051 \| macular oedema \| 2 C0011303 \| demyelinating disorders \| 2 C0006111 \| brain disease \| 2 C0042373 \| vascular diseases \| 2 C0003635 \| apraxia \| 2 C0028754 \| obesity \| 2 C0035435 \| rheumatic diseases \| 2 C0004096 \| asthma \| 2 C0014544 \| epileptic seizure \| 2 C0007760 \| cerebellar dysfunction \| 2 C0007222 \| cardiovascular diseases \| 2 C0028768 \| obsessive-compulsive disorder \| 2 C0027051 \| myocardial infarct \| 2 C0035435 \| rheumatic disease \| 2 C0007222 \| cardiovascular disease \| 2 C0032708 \| porphyria \| 2 C0019196 \| hepatitis c \| 1 C0034063 \| pulmonary edema \| 1 C0039494 \| temporomandibular disorders \| 1 C0018378 \| guillain-barre syndrome \| 1 C0030486 \| paraplegia \| 1 C0021359 \| infertility \| 1 C0238432 \| spinal cord ependymoma \| 1 C0023895 \| hepatopathy \| 1 C0021053 \| immune disorder \| 1 C0747256 \| parasitic infection \| 1 C0040128 \| thyroid disease \| 1 C0023487 \| promyelocytic leukemia \| 1 C0036337 \| schizoaffective disorder \| 1 C0743039 \| progressive dementia \| 1 C0023646 \| lichen ruber planus \| 1 C0035920 \| rubella \| 1 C0007789 \| cerebral palsy \| 1 C0037274 \| skin disorder \| 1 C0037928 \| myelopathy \| 1 C1261473 \| sarcoma \| 1 C0878544 \| cardiomyopathy \| 1 C0023524 \| progressive multifocal leucoencephalopathy \| 1 C0026846 \| muscular atrophy \| 1 C0035258 \| restless legs syndrome (rls) \| 1 C0547030 \| visual disturbance \| 1 C0003873 \| rheumatoid arthritis \| 1 C0021831 \| bowel disease \| 1 C0014130 \| endocrine disease \| 1 C0040053 \| thrombosis \| 1 C0008148 \| chlamydia \| 1 C0018784 \| sensorineural hearing loss \| 1 C0004712 \| balo's concentric sclerosis \| 1 C0004943 \| behcet's disease \| 1 C0038013 \| ankylosing spondylitis \| 1 C0014175 \| endometriosis \| 1 C0018213 \| graves' disease \| 1 C0029132 \| optic neuropathy \| 1 C0162565 \| acute porphyria \| 1 C0009326 \| collagen disease \| 1 C0042870 \| vitamin d defic \| 1 C0024312 \| lymphopenia \| 1 C0010346 \| crohn disease \| 1 C0017665 \| membranous glomerulopathy \| 1 C0948265 \| metabolic syndrome \| 1 C0162566 \| porphyria cutanea tarda \| 1 C0036341 \| schizophrenia \| 1 C0013421 \| dystonia \| 1 C0024141 \| systemic lupus erythematosus \| 1 C0036202 \| sarcoidosis \| 1 C0021053 \| immune disorders \| 1 C0006142 \| breast cancer \| 1 C0152134 \| internuclear ophthalmoplegia \| 1 C0162674 \| progressive external ophthalmoplegia \| 1 C0024530 \| malaria \| 1 C0018801 \| cardiac failure \| 1 C0032285 \| pneumoniae \| 1 C0009326 \| collagen diseases \| 1 C0021053 \| immunological diseases \| 1 C0001824 \| agranulocytosis \| 1 C0085278 \| antiphospholipid syndrome \| 1 C0017921 \| pompe disease \| 1 C0023487 \| acute promyelocytic leukemia \| 1 C0042847 \| vitamin b12 defic \| 1 C0270853 \| juvenile myoclonic epilepsy \| 1 C0022073 \| iridocyclitis \| 1 C0030567 \| parkinson's disease \| 1 C0039494 \| temporomandibular joint disorder \| 1 C0004153 \| atherosclerosis \| 1 C0154731 \| glossopharyngeal neuralgia \| 1 C0023890 \| cirrhosis \| 1 C0037315 \| sleep-disordered breathing \| 1 C0079840 \| milk allergy \| 1 C0010414 \| cryptococcosis \| 1 C0159069 \| impaired glucose tolerance \| 1 C0024198 \| lyme disease \| 1 C0042847 \| vitamin b12 deficiency \| 1 C0014059 \| acute disseminated encephalomyelitis \| 1 C0751878 \| cns vasculitis \| 1 C0030524 \| paratuberculosis \| 1 C0282193 \| iron overload \| 1 C0041318 \| tuberculous meningitis \| 1 C0037274 \| skin disorders \| 1 C0028754 \| adiposity \| 1 C0034372 \| tetraplegia \| 1 C0018378 \| guillain barre syndrome \| 1 C0038012 \| spondylitis \| 1 C0026636 \| oral disease \| 1 C0009324 \| ulcerative colitis \| 1 C0021053 \| immunological disease \| 1 C0026850 \| muscular dystrophy \| 1 C0034063 \| pulmonary oedema \| 1 C0002766 \| analgesia \| 1 C1389280 \| basal ganglia calcification \| 1 C0023470 \| myelocytic leukemia \| 1 C0020676 \| hypothyroidism \| 1 C0004936 \| mental disorders \| 1 C0036220 \| kaposi sarcoma \| 1 C0017636 \| glioblastoma \| 1 C0008312 \| biliary cirrhosis \| 1 C0014038 \| brain inflammation \| 1 C0409974 \| lupus erythematosus \| 1 C0039494 \| temporomandibular disorder \| 1 C0034150 \| purpura \| 1 C0038220 \| status epilepticus \| 1 C0027726 \| nephrotic syndrome \| 1 C0030593 \| pars planitis \| 1 C0751651 \| mitochondrial disorder \| 1 C0013473 \| eating disorder \| 1 C0025289 \| meningitis \| 1 C0020179 \| huntington's disease \| 1 C0086543 \| cataract \| 1 C0014130 \| endocrine diseases \| 1 C0026946 \| fungal infection \| 1 C0035309 \| retinopathy \| 1 C0042870 \| vitamin d deficiency \| 1 C0002874 \| aplastic anemia \| 1 C1333387 \| endocrine syndrome \| 1 C0178238 \| intestinal infection \| 1 C0024440 \| cystoid macular oedema \| 1 C0042769 \| viral infections \| 1 C0008312 \| primary biliary cirrhosis \| 1 C2004461 \| bowel dysfunction \| 1 C0011303 \| demyelinating diseases \| 1 C0242379 \| lung cancer \| 1 C0037928 \| spinal cord disease \| 1 C0043117 \| immune thrombocytopenic purpura \| 1 C0751878 \| central nervous system vasculitis \| 1 C0178238 \| intestinal infections \| 1 C0019569 \| hirschsprung's disease \| 1 C0162809 \| kallmann syndrome \| 1 C1527336 \| sjogren syndrome \| 1 C0042769 \| viral infection \| 1 C0004659 \| bacteriuria \| 1 C0751651 \| mitochondrial disorders \| 1 C0041696 \| major depressive disorder \| 1 C0520680 \| central sleep apnea \| 1 C0023418 \| leukemia \| 1 C0003872 \| psoriatic arthritis \| 1 C0175702 \| williams-beuren syndrome \| 1 C0085582 \| retrobulbar neuritis \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:98) HLA-DRB1 \| 3123 \| CTD_human;GHR CLEC16A \| 23274 \| CTD_human;GWASCAT ICAM1 \| 3383 \| CTD_human CNR1 \| 1268 \| CTD_human POMC \| 5443 \| CTD_human BACH2 \| 60468 \| GWASCAT STAT3 \| 6774 \| GWASCAT CD40 \| 958 \| CTD_human SUMF1 \| 285362 \| GWASCAT APOE \| 348 \| CTD_human VCAM1 \| 7412 \| CTD_human KIF1B \| 23095 \| CTD_human;GWASCAT C1orf106 \| 55765 \| GWASCAT C6orf10 \| 10665 \| GWASCAT TNFAIP3 \| 7128 \| CTD_human CBLB \| 868 \| CTD_human;GWASCAT STAT4 \| 6775 \| CTD_human IL1B \| 3553 \| CTD_human PTPRC \| 5788 \| CTD_human HLA-DPB1 \| 3115 \| CTD_human MGAT5 \| 4249 \| GWASCAT BTNL2 \| 56244 \| GWASCAT CD58 \| 965 \| CTD_human;GWASCAT CYP27B1 \| 1594 \| GWASCAT;GHR TYK2 \| 7297 \| CTD_human BCHE \| 590 \| CTD_human TNFRSF1A \| 7132 \| CTD_human;GWASCAT;GHR MPHOSPH9 \| 10198 \| GWASCAT ODF3B \| 440836 \| GWASCAT PRKRA \| 8575 \| GWASCAT HLA-DQB1 \| 3119 \| CTD_human SELE \| 6401 \| CTD_human KCNJ10 \| 3766 \| CTD_human CLSTN2 \| 64084 \| GWASCAT IL2RA \| 3559 \| CTD_human;GWASCAT;GHR HACE1 \| 57531 \| GWASCAT METTL1 \| 4234 \| GWASCAT SP140 \| 11262 \| GWASCAT CLECL1 \| 160365 \| GWASCAT BATF \| 10538 \| GWASCAT SLC11A1 \| 6556 \| CTD_human MERTK \| 10461 \| GWASCAT CD86 \| 942 \| GWASCAT MAPK1 \| 5594 \| GWASCAT TAGAP \| 117289 \| GWASCAT GPC5 \| 2262 \| GWASCAT ARHGEF10 \| 9639 \| GWASCAT RPS6KB1 \| 6198 \| GWASCAT ZFP36L1 \| 677 \| GWASCAT TNFSF14 \| 8740 \| CTD_human;GWASCAT PDCD1 \| 5133 \| CTD_human PVR \| 5817 \| GWASCAT ZBTB46 \| 140685 \| GWASCAT IRF8 \| 3394 \| CTD_human MIR548AC \| 100616384 \| GWASCAT IFNB1 \| 3456 \| CTD_human IL7R \| 3575 \| CTD_human;GWASCAT;GHR ZMIZ1 \| 57178 \| GWASCAT HLA-DRA \| 3122 \| CTD_human;GWASCAT MCAM \| 4162 \| CTD_human DKKL1 \| 27120 \| GWASCAT P2RX7 \| 5027 \| CTD_human MYNN \| 55892 \| GWASCAT CIITA \| 4261 \| CTD_human DLEU1 \| 10301 \| GWASCAT CYP24A1 \| 1591 \| GWASCAT RNASEL \| 6041 \| GWASCAT IL7 \| 3574 \| CTD_human MANBA \| 4126 \| GWASCAT RGS14 \| 10636 \| GWASCAT IL12A \| 3592 \| CTD_human AGAP2 \| 116986 \| GWASCAT CD6 \| 923 \| CTD_human;GWASCAT MLANA \| 2315 \| GWASCAT MPV17L2 \| 84769 \| GWASCAT VAV2 \| 7410 \| GWASCAT AHI1 \| 54806 \| GWASCAT SPEF2 \| 79925 \| GWASCAT RAD21L1 \| 642636 \| GWASCAT EPS15L1 \| 58513 \| GWASCAT ZNF433 \| 163059 \| GWASCAT CXCR5 \| 643 \| GWASCAT TIMMDC1 \| 51300 \| GWASCAT SLC30A7 \| 148867 \| GWASCAT HLA-F-AS1 \| 285830 \| GWASCAT ZNF767P \| 79970 \| GWASCAT SLC15A2 \| 6565 \| GWASCAT MS \| 4397 \| CTD_human C1orf204 \| 284677 \| GWASCAT MALT1 \| 10892 \| GWASCAT CLDN11 \| 5010 \| CTD_human NCOA5 \| 57727 \| GWASCAT EVI5 \| 7813 \| GWASCAT SYK \| 6850 \| GWASCAT CD24 \| 100133941 \| CTD_human HLA-DRB6 \| 3128 \| GWASCAT HLA-F \| 3134 \| GWASCAT SAE1 \| 10055 \| GWASCAT
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:578) 2 \| A2M \| infer 1636 \| ACE \| infer 132612 \| ADAD1 \| infer 140766 \| ADAMTS14 \| infer 116 \| ADCYAP1 \| infer 154 \| ADRB2 \| infer 54806 \| AHI1 \| infer 199 \| AIF1 \| infer 10000 \| AKT3 \| infer 238 \| ALK \| infer 57679 \| ALS2 \| infer 328 \| APEX1 \| infer 27301 \| APEX2 \| infer 335 \| APOA1 \| infer 341 \| APOC1 \| infer 344 \| APOC2 \| infer 348 \| APOE \| infer 50807 \| ASAP1 \| infer 6311 \| ATXN2 \| infer 60468 \| BACH2 \| infer 10538 \| BATF \| infer 581 \| BAX \| infer 8915 \| BCL10 \| infer 596 \| BCL2 \| infer 598 \| BCL2L1 \| infer 627 \| BDNF \| infer 636 \| BICD1 \| infer 672 \| BRCA1 \| infer 675 \| BRCA2 \| infer 26580 \| BSCL2 \| infer 56244 \| BTNL2 \| infer 56913 \| C1GALT1 \| infer 717 \| C2 \| infer 729 \| C6 \| infer 10665 \| C6orf10 \| infer 730 \| C7 \| infer 27092 \| CACNG4 \| infer 843 \| CASP10 \| infer 835 \| CASP2 \| infer 836 \| CASP3 \| infer 838 \| CASP5 \| infer 840 \| CASP7 \| infer 841 \| CASP8 \| infer 842 \| CASP9 \| infer 868 \| CBLB \| infer 6346 \| CCL1 \| infer 6356 \| CCL11 \| infer 6357 \| CCL13 \| infer 6361 \| CCL17 \| infer 6347 \| CCL2 \| infer 6367 \| CCL22 \| infer 6348 \| CCL3 \| infer 6352 \| CCL5 \| infer 6354 \| CCL7 \| infer 6355 \| CCL8 \| infer 902 \| CCNH \| infer 1230 \| CCR1 \| infer 729230 \| CCR2 \| infer 1234 \| CCR5 \| infer 929 \| CD14 \| infer 909 \| CD1A \| infer 913 \| CD1E \| infer 10666 \| CD226 \| infer 100133941 \| CD24 \| infer 29126 \| CD274 \| infer 940 \| CD28 \| infer 920 \| CD4 \| infer 958 \| CD40 \| infer 965 \| CD58 \| infer 923 \| CD6 \| infer 941 \| CD80 \| infer 9308 \| CD83 \| infer 942 \| CD86 \| infer 1022 \| CDK7 \| infer 1041 \| CDSN \| infer 9859 \| CEP170 \| infer 629 \| CFB \| infer 8837 \| CFLAR \| infer 1122 \| CHML \| infer 1129 \| CHRM2 \| infer 1131 \| CHRM3 \| infer 4261 \| CIITA \| infer 23274 \| CLEC16A \| infer 160365 \| CLECL1 \| infer 1268 \| CNR1 \| infer 1270 \| CNTF \| infer 1312 \| COMT \| infer 27151 \| CPAMD8 \| infer 1410 \| CRYAB \| infer 64478 \| CSMD1 \| infer 1493 \| CTLA4 \| infer 29119 \| CTNNA3 \| infer 1520 \| CTSS \| infer 404093 \| CUEDC1 \| infer 3627 \| CXCL10 \| infer 6387 \| CXCL12 \| infer 7852 \| CXCR4 \| infer 643 \| CXCR5 \| infer 360170 \| CYCSP14 \| infer 1591 \| CYP24A1 \| infer 1594 \| CYP27B1 \| infer 1565 \| CYP2D6 \| infer 120227 \| CYP2R1 \| infer 1601 \| DAB2 \| infer 1621 \| DBH \| infer 1628 \| DBP \| infer 54798 \| DCHS2 \| infer 64421 \| DCLRE1C \| infer 1639 \| DCTN1 \| infer 1643 \| DDB2 \| infer 23586 \| DDX58 \| infer 729816 \| DHFRP2 \| infer 8449 \| DHX16 \| infer 27120 \| DKKL1 \| infer 1814 \| DRD3 \| infer 401124 \| DTHD1 \| infer 1843 \| DUSP1 \| infer 9718 \| ECE2 \| infer 10919 \| EHMT2 \| infer 8893 \| EIF2B5 \| infer 84337 \| ELOF1 \| infer 146956 \| EME1 \| infer 2019 \| EN1 \| infer 8320 \| EOMES \| infer 58513 \| EPS15L1 \| infer 2065 \| ERBB3 \| infer 2067 \| ERCC1 \| infer 2068 \| ERCC2 \| infer 2071 \| ERCC3 \| infer 2072 \| ERCC4 \| infer 2073 \| ERCC5 \| infer 2074 \| ERCC6 \| infer 1161 \| ERCC8 \| infer 2099 \| ESR1 \| infer 7813 \| EVI5 \| infer 9156 \| EXO1 \| infer 388650 \| FAM69A \| infer 355 \| FAS \| infer 356 \| FASLG \| infer 2212 \| FCGR2A \| infer 2214 \| FCGR3A \| infer 2215 \| FCGR3B \| infer 115352 \| FCRL3 \| infer 2237 \| FEN1 \| infer 2246 \| FGF1 \| infer 2271 \| FH \| infer 10211 \| FLOT1 \| infer 56776 \| FMN2 \| infer 2309 \| FOXO3 \| infer 2524 \| FUT2 \| infer 2550 \| GABBR1 \| infer 2556 \| GABRA3 \| infer 2633 \| GBP1 \| infer 2638 \| GC \| infer 25801 \| GCA \| infer 2672 \| GFI1 \| infer 2696 \| GIPR \| infer 2739 \| GLO1 \| infer 2784 \| GNB3 \| infer 2262 \| GPC5 \| infer 10082 \| GPC6 \| infer 8477 \| GPR65 \| infer 64388 \| GREM2 \| infer 2944 \| GSTM1 \| infer 2952 \| GSTT1 \| infer 2965 \| GTF2H1 \| infer 2968 \| GTF2H4 \| infer 404672 \| GTF2H5 \| infer 9563 \| H6PD \| infer 23498 \| HAAO \| infer 26762 \| HAVCR1 \| infer 10767 \| HBS1L \| infer 414777 \| HCG18 \| infer 352961 \| HCG26 \| infer 253018 \| HCG27 \| infer 54435 \| HCG4 \| infer 353005 \| HCG4P8 \| infer 10255 \| HCG9 \| infer 9931 \| HELZ \| infer 3077 \| HFE \| infer 3087 \| HHEX \| infer 3105 \| HLA-A \| infer 3106 \| HLA-B \| infer 3107 \| HLA-C \| infer 3108 \| HLA-DMA \| infer 3109 \| HLA-DMB \| infer 3115 \| HLA-DPB1 \| infer 3117 \| HLA-DQA1 \| infer 3118 \| HLA-DQA2 \| infer 3119 \| HLA-DQB1 \| infer 3120 \| HLA-DQB2 \| infer 3122 \| HLA-DRA \| infer 3123 \| HLA-DRB1 \| infer 3127 \| HLA-DRB5 \| infer 3132 \| HLA-DRB9 \| infer 3134 \| HLA-F \| infer 3135 \| HLA-G \| infer 3137 \| HLA-J \| infer 267015 \| HLA-S \| infer 3176 \| HNMT \| infer 100131609 \| HNRNPA1P2 \| infer 9956 \| HS3ST2 \| infer 3303 \| HSPA1A \| infer 3304 \| HSPA1B \| infer 3305 \| HSPA1L \| infer 3315 \| HSPB1 \| infer 3316 \| HSPB2 \| infer 3329 \| HSPD1 \| infer 3383 \| ICAM1 \| infer 29851 \| ICOS \| infer 3620 \| IDO1 \| infer 8870 \| IER3 \| infer 64135 \| IFIH1 \| infer 3451 \| IFNA17 \| infer 3454 \| IFNAR1 \| infer 3455 \| IFNAR2 \| infer 3456 \| IFNB1 \| infer 3458 \| IFNG \| infer 3459 \| IFNGR1 \| infer 3460 \| IFNGR2 \| infer 3482 \| IGF2R \| infer 28400 \| IGHV4-28 \| infer 3586 \| IL10 \| infer 3590 \| IL11RA \| infer 3592 \| IL12A \| infer 3593 \| IL12B \| infer 3595 \| IL12RB2 \| infer 3596 \| IL13 \| infer 3605 \| IL17A \| infer 8809 \| IL18R1 \| infer 3552 \| IL1A \| infer 3553 \| IL1B \| infer 3554 \| IL1R1 \| infer 3557 \| IL1RN \| infer 3558 \| IL2 \| infer 53832 \| IL20RA \| infer 59067 \| IL21 \| infer 50615 \| IL21R \| infer 149233 \| IL23R \| infer 55801 \| IL26 \| infer 3559 \| IL2RA \| infer 3560 \| IL2RB \| infer 3562 \| IL3 \| infer 3565 \| IL4 \| infer 3566 \| IL4R \| infer 3567 \| IL5 \| infer 3568 \| IL5RA \| infer 3569 \| IL6 \| infer 3574 \| IL7 \| infer 3575 \| IL7R \| infer 3578 \| IL9 \| infer 286676 \| ILDR1 \| infer 51141 \| INSIG2 \| infer 3659 \| IRF1 \| infer 3662 \| IRF4 \| infer 3663 \| IRF5 \| infer 3394 \| IRF8 \| infer 10379 \| IRF9 \| infer 3676 \| ITGA4 \| infer 182 \| JAG1 \| infer 3716 \| JAK1 \| infer 3717 \| JAK2 \| infer 23189 \| KANK1 \| infer 90134 \| KCNH7 \| infer 30820 \| KCNIP1 \| infer 23095 \| KIF1B \| infer 23046 \| KIF21B \| infer 3798 \| KIF5A \| infer 3802 \| KIR2DL1 \| infer 3803 \| KIR2DL2 \| infer 3804 \| KIR2DL3 \| infer 3805 \| KIR2DL4 \| infer 57292 \| KIR2DL5A \| infer 554300 \| KIR2DP1 \| infer 3806 \| KIR2DS1 \| infer 100132285 \| KIR2DS2 \| infer 3808 \| KIR2DS3 \| infer 3809 \| KIR2DS4 \| infer 3810 \| KIR2DS5 \| infer 3811 \| KIR3DL1 \| infer 3812 \| KIR3DL2 \| infer 115653 \| KIR3DL3 \| infer 3813 \| KIR3DS1 \| infer 3820 \| KLRB1 \| infer 8564 \| KMO \| infer 3837 \| KPNB1 \| infer 3897 \| L1CAM \| infer 3902 \| LAG3 \| infer 389170 \| LEKR1 \| infer 3952 \| LEP \| infer 3976 \| LIF \| infer 3980 \| LIG3 \| infer 3981 \| LIG4 \| infer 11026 \| LILRA3 \| infer 9516 \| LITAF \| infer 4001 \| LMNB1 \| infer 4035 \| LRP1 \| infer 4049 \| LTA \| infer 4099 \| MAG \| infer 10892 \| MALT1 \| infer 4126 \| MANBA \| infer 5594 \| MAPK1 \| infer 8930 \| MBD4 \| infer 4155 \| MBP \| infer 4157 \| MC1R \| infer 401250 \| MCCD1 \| infer 4210 \| MEFV \| infer 10461 \| MERTK \| infer 4233 \| MET \| infer 4234 \| METTL1 \| infer 4249 \| MGAT5 \| infer 100507436 \| MICA \| infer 4277 \| MICB \| infer 4279 \| MICD \| infer 4282 \| MIF \| infer 2315 \| MLANA \| infer 4312 \| MMP1 \| infer 4321 \| MMP12 \| infer 4313 \| MMP2 \| infer 4314 \| MMP3 \| infer 4316 \| MMP7 \| infer 4318 \| MMP9 \| infer 64210 \| MMS19 \| infer 4331 \| MNAT1 \| infer 4340 \| MOG \| infer 4350 \| MPG \| infer 10198 \| MPHOSPH9 \| infer 4353 \| MPO \| infer 84769 \| MPV17L2 \| infer 359758 \| MRPS17P5 \| infer 4508 \| MT-ATP6 \| infer 4509 \| MT-ATP8 \| infer 4513 \| MT-CO2 \| infer 140909 \| MTCO2P1 \| infer 4524 \| MTHFR \| infer 4535 \| MT-ND1 \| infer 4552 \| MTRR \| infer 4566 \| MT-TK \| infer 80198 \| MUS81 \| infer 4595 \| MUTYH \| infer 4599 \| MX1 \| infer 4601 \| MXI1 \| infer 55892 \| MYNN \| infer 4650 \| MYO9B \| infer 4683 \| NBN \| infer 344148 \| NCKAP5 \| infer 80762 \| NDFIP1 \| infer 4720 \| NDUFS2 \| infer 4744 \| NEFH \| infer 79661 \| NEIL1 \| infer 252969 \| NEIL2 \| infer 4795 \| NFKBIL1 \| infer 64332 \| NFKBIZ \| infer 4803 \| NGF \| infer 4804 \| NGFR \| infer 79840 \| NHEJ1 \| infer 123606 \| NIPA1 \| infer 204801 \| NLRP11 \| infer 64127 \| NOD2 \| infer 4842 \| NOS1 \| infer 4846 \| NOS3 \| infer 4854 \| NOTCH3 \| infer 4855 \| NOTCH4 \| infer 2908 \| NR3C1 \| infer 4913 \| NTHL1 \| infer 80224 \| NUBPL \| infer 4938 \| OAS1 \| infer 440836 \| ODF3B \| infer 4968 \| OGG1 \| infer 167826 \| OLIG3 \| infer 23596 \| OPN3 \| infer 81797 \| OR12D3 \| infer 26716 \| OR2H1 \| infer 7932 \| OR2H2 \| infer 26578 \| OSTF1 \| infer 23569 \| PADI4 \| infer 5048 \| PAFAH1B1 \| infer 142 \| PARP1 \| infer 10038 \| PARP2 \| infer 5111 \| PCNA \| infer 5125 \| PCSK5 \| infer 5133 \| PDCD1 \| infer 5142 \| PDE4B \| infer 29951 \| PDZRN4 \| infer 5175 \| PECAM1 \| infer 9749 \| PHACTR2 \| infer 8554 \| PIAS1 \| infer 5328 \| PLAU \| infer 5335 \| PLCG1 \| infer 200150 \| PLD5 \| infer 5341 \| PLEK \| infer 5354 \| PLP1 \| infer 5366 \| PMAIP1 \| infer 5376 \| PMP22 \| infer 11284 \| PNKP \| infer 5409 \| PNMT \| infer 87178 \| PNPT1 \| infer 5423 \| POLB \| infer 5424 \| POLD1 \| infer 5426 \| POLE \| infer 5428 \| POLG \| infer 5444 \| PON1 \| infer 64208 \| POPDC3 \| infer 5450 \| POU2AF1 \| infer 5460 \| POU5F1 \| infer 5465 \| PPARA \| infer 5468 \| PPARG \| infer 100131033 \| PPIGP1 \| infer 6992 \| PPP1R11 \| infer 5551 \| PRF1 \| infer 5578 \| PRKCA \| infer 5591 \| PRKDC \| infer 8575 \| PRKRA \| infer 5619 \| PRM1 \| infer 5621 \| PRNP \| infer 5696 \| PSMB8 \| infer 5698 \| PSMB9 \| infer 5708 \| PSMD2 \| infer 170679 \| PSORS1C1 \| infer 100130889 \| PSORS1C3 \| infer 5724 \| PTAFR \| infer 5734 \| PTGER4 \| infer 5743 \| PTGS2 \| infer 5747 \| PTK2 \| infer 26191 \| PTPN22 \| infer 5786 \| PTPRA \| infer 5788 \| PTPRC \| infer 5817 \| PVR \| infer 5820 \| PVT1 \| infer 642636 \| RAD21L1 \| infer 5886 \| RAD23A \| infer 5887 \| RAD23B \| infer 5888 \| RAD51 \| infer 5889 \| RAD51C \| infer 5893 \| RAD52 \| infer 25788 \| RAD54B \| infer 8438 \| RAD54L \| infer 221002 \| RASGEF1A \| infer 157506 \| RDH10 \| infer 5649 \| RELN \| infer 5981 \| RFC1 \| infer 5982 \| RFC2 \| infer 5984 \| RFC4 \| infer 5985 \| RFC5 \| infer 56963 \| RGMA \| infer 5996 \| RGS1 \| infer 10636 \| RGS14 \| infer 5997 \| RGS2 \| infer 6000 \| RGS7 \| infer 80352 \| RNF39 \| infer 6117 \| RPA1 \| infer 6118 \| RPA2 \| infer 6119 \| RPA3 \| infer 128500 \| RPL13P2 \| infer 100128347 \| RPL15P15 \| infer 391719 \| RPL19P8 \| infer 319145 \| RPL21P8 \| infer 6148 \| RPL23AP1 \| infer 100270977 \| RPL30P3 \| infer 6125 \| RPL5 \| infer 100271091 \| RPS23P3 \| infer 100270859 \| RPS2P19 \| infer 342808 \| RPS2P6 \| infer 6198 \| RPS6KB1 \| infer 100270870 \| RPS7P7 \| infer 6262 \| RYR2 \| infer 10055 \| SAE1 \| infer 10806 \| SDCCAG8 \| infer 6401 \| SELE \| infer 6402 \| SELL \| infer 6403 \| SELP \| infer 6404 \| SELPLG \| infer 5054 \| SERPINE1 \| infer 143686 \| SESN3 \| infer 23064 \| SETX \| infer 10019 \| SH2B3 \| infer 9047 \| SH2D2A \| infer 6456 \| SH3GL2 \| infer 6556 \| SLC11A1 \| infer 6565 \| SLC15A2 \| infer 9481 \| SLC25A27 \| infer 55186 \| SLC25A36 \| infer 148867 \| SLC30A7 \| infer 80736 \| SLC44A4 \| infer 23583 \| SMUG1 \| infer 6647 \| SOD1 \| infer 30812 \| SOX8 \| infer 11262 \| SP140 \| infer 8404 \| SPARCL1 \| infer 6683 \| SPAST \| infer 79925 \| SPEF2 \| infer 23111 \| SPG20 \| infer 6687 \| SPG7 \| infer 6696 \| SPP1 \| infer 145165 \| ST13P4 \| infer 6489 \| ST8SIA1 \| infer 6772 \| STAT1 \| infer 6774 \| STAT3 \| infer 27067 \| STAU2 \| infer 3925 \| STMN1 \| infer 285362 \| SUMF1 \| infer 6840 \| SVIL \| infer 6850 \| SYK \| infer 8224 \| SYN3 \| infer 6863 \| TAC1 \| infer 6866 \| TAC3 \| infer 255061 \| TAC4 \| infer 117289 \| TAGAP \| infer 6890 \| TAP1 \| infer 6891 \| TAP2 \| infer 55357 \| TBC1D2 \| infer 6941 \| TCF19 \| infer 6932 \| TCF7 \| infer 6996 \| TDG \| infer 7040 \| TGFB1 \| infer 7054 \| TH \| infer 7096 \| TLR1 \| infer 81793 \| TLR10 \| infer 7097 \| TLR2 \| infer 7098 \| TLR3 \| infer 7099 \| TLR4 \| infer 7100 \| TLR5 \| infer 10333 \| TLR6 \| infer 51284 \| TLR7 \| infer 51311 \| TLR8 \| infer 54106 \| TLR9 \| infer 65084 \| TMEM135 \| infer 55254 \| TMEM39A \| infer 7124 \| TNF \| infer 7128 \| TNFAIP3 \| infer 7132 \| TNFRSF1A \| infer 7133 \| TNFRSF1B \| infer 8743 \| TNFSF10 \| infer 8740 \| TNFSF14 \| infer 7148 \| TNXB \| infer 7157 \| TP53 \| infer 10107 \| TRIM10 \| infer 89870 \| TRIM15 \| infer 23321 \| TRIM2 \| infer 7726 \| TRIM26 \| infer 135644 \| TRIM40 \| infer 287015 \| TRIM42 \| infer 8989 \| TRPA1 \| infer 203068 \| TUBB \| infer 7297 \| TYK2 \| infer 7299 \| TYR \| infer 10537 \| UBD \| infer 7351 \| UCP2 \| infer 54573 \| UGT1A12P \| infer 9217 \| VAPB \| infer 7410 \| VAV2 \| infer 7412 \| VCAM1 \| infer 7416 \| VDAC1 \| infer 7421 \| VDR \| infer 7422 \| VEGFA \| infer 7432 \| VIP \| infer 387122 \| WASF5P \| infer 128025 \| WDR64 \| infer 23335 \| WDR7 \| infer 7486 \| WRN \| infer 56949 \| XAB2 \| infer 7507 \| XPA \| infer 7508 \| XPC \| infer 7515 \| XRCC1 \| infer 7516 \| XRCC2 \| infer 7517 \| XRCC3 \| infer 7518 \| XRCC4 \| infer 7520 \| XRCC5 \| infer 2547 \| XRCC6 \| infer 7532 \| YWHAG \| infer 221527 \| ZBTB12 \| infer 140685 \| ZBTB46 \| infer 677 \| ZFP36L1 \| infer 7545 \| ZIC1 \| infer 57178 \| ZMIZ1 \| infer 163059 \| ZNF433 \| infer 7596 \| ZNF45 \| infer 57829 \| ZP4 \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:1000) 618 \| BCYRN1 \| DISEASES 10301 \| DLEU1 \| DISEASES 6376 \| CX3CL1 \| DISEASES 4706 \| NDUFAB1 \| DISEASES 8993 \| PGLYRP1 \| DISEASES 972 \| CD74 \| DISEASES 65078 \| RTN4R \| DISEASES 5010 \| CLDN11 \| DISEASES 933 \| CD22 \| DISEASES 3385 \| ICAM3 \| DISEASES 7132 \| TNFRSF1A \| DISEASES 3566 \| IL4R \| DISEASES 9817 \| KEAP1 \| DISEASES 4804 \| NGFR \| DISEASES 30009 \| TBX21 \| DISEASES 54700 \| RRN3 \| DISEASES 3902 \| LAG3 \| DISEASES 350 \| APOH \| DISEASES 2099 \| ESR1 \| DISEASES 51310 \| SLC22A17 \| DISEASES 23411 \| SIRT1 \| DISEASES 4616 \| GADD45B \| DISEASES 8174 \| MADCAM1 \| DISEASES 4282 \| MIF \| DISEASES 5008 \| OSM \| DISEASES 11274 \| USP18 \| DISEASES 5594 \| MAPK1 \| DISEASES 57026 \| PDXP \| DISEASES 3162 \| HMOX1 \| DISEASES 3560 \| IL2RB \| DISEASES 1511 \| CTSG \| DISEASES 3002 \| GZMB \| DISEASES 623 \| BDKRB1 \| DISEASES 4792 \| NFKBIA \| DISEASES 1591 \| CYP24A1 \| DISEASES 10857 \| PGRMC1 \| DISEASES 7076 \| TIMP1 \| DISEASES 4313 \| MMP2 \| DISEASES 6367 \| CCL22 \| DISEASES 1723 \| DHODH \| DISEASES 6361 \| CCL17 \| DISEASES 4324 \| MMP15 \| DISEASES 4210 \| MEFV \| DISEASES 3163 \| HMOX2 \| DISEASES 30844 \| EHD4 \| DISEASES 8767 \| RIPK2 \| DISEASES 10404 \| CPQ \| DISEASES 1666 \| DECR1 \| DISEASES 5327 \| PLAT \| DISEASES 2765 \| GML \| DISEASES 2936 \| GSR \| DISEASES 8797 \| TNFRSF10A \| DISEASES 4741 \| NEFM \| DISEASES 4051 \| CYP4F3 \| DISEASES 3191 \| HNRNPL \| DISEASES 3743 \| KCNA7 \| DISEASES 57030 \| SLC17A7 \| DISEASES 7040 \| TGFB1 \| DISEASES 973 \| CD79A \| DISEASES 5444 \| PON1 \| DISEASES 10392 \| NOD1 \| DISEASES 5054 \| SERPINE1 \| DISEASES 727 \| C5 \| DISEASES 7431 \| VIM \| DISEASES 6348 \| CCL3 \| DISEASES 4353 \| MPO \| DISEASES 1440 \| CSF3 \| DISEASES 23729 \| SHPK \| DISEASES 8402 \| SLC25A11 \| DISEASES 40 \| ASIC2 \| DISEASES 6347 \| CCL2 \| DISEASES 6346 \| CCL1 \| DISEASES 6357 \| CCL13 \| DISEASES 29098 \| RANGRF \| DISEASES 952 \| CD38 \| DISEASES 4790 \| NFKB1 \| DISEASES 3558 \| IL2 \| DISEASES 51166 \| AADAT \| DISEASES 1410 \| CRYAB \| DISEASES 3312 \| HSPA8 \| DISEASES 24145 \| PANX1 \| DISEASES 3587 \| IL10RA \| DISEASES 9733 \| SART3 \| DISEASES 969 \| CD69 \| DISEASES 6404 \| SELPLG \| DISEASES 41 \| ASIC1 \| DISEASES 51561 \| IL23A \| DISEASES 1594 \| CYP27B1 \| DISEASES 4055 \| LTBR \| DISEASES 55801 \| IL26 \| DISEASES 3458 \| IFNG \| DISEASES 2597 \| GAPDH \| DISEASES 2026 \| ENO2 \| DISEASES 339 \| APOBEC1 \| DISEASES 3820 \| KLRB1 \| DISEASES 1432 \| MAPK14 \| DISEASES 10279 \| PRSS16 \| DISEASES 1839 \| HBEGF \| DISEASES 3565 \| IL4 \| DISEASES 3567 \| IL5 \| DISEASES 2908 \| NR3C1 \| DISEASES 4820 \| NKTR \| DISEASES 26528 \| DAZAP1 \| DISEASES 6556 \| SLC11A1 \| DISEASES 3336 \| HSPE1 \| DISEASES 3554 \| IL1R1 \| DISEASES 6509 \| SLC1A4 \| DISEASES 6402 \| SELL \| DISEASES 1509 \| CTSD \| DISEASES 4317 \| MMP8 \| DISEASES 335 \| APOA1 \| DISEASES 7276 \| TTR \| DISEASES 7128 \| TNFAIP3 \| DISEASES 7043 \| TGFB3 \| DISEASES 23433 \| RHOQ \| DISEASES 4360 \| MRC1 \| DISEASES 23435 \| TARDBP \| DISEASES 10804 \| GJB6 \| DISEASES 8743 \| TNFSF10 \| DISEASES 4852 \| NPY \| DISEASES 1271 \| CNTFR \| DISEASES 1959 \| EGR2 \| DISEASES 84329 \| HVCN1 \| DISEASES 4035 \| LRP1 \| DISEASES 2166 \| FAAH \| DISEASES 6626 \| SNRPA \| DISEASES 696 \| BTN1A1 \| DISEASES 6631 \| SNRPC \| DISEASES 583 \| BBS2 \| DISEASES 56848 \| SPHK2 \| DISEASES 3659 \| IRF1 \| DISEASES 8744 \| TNFSF9 \| DISEASES 970 \| CD70 \| DISEASES 718 \| C3 \| DISEASES 8698 \| S1PR4 \| DISEASES 10893 \| MMP24 \| DISEASES 1236 \| CCR7 \| DISEASES 5199 \| CFP \| DISEASES 4974 \| OMG \| DISEASES 821 \| CANX \| DISEASES 84769 \| MPV17L2 \| DISEASES 391013 \| PLA2G2C \| DISEASES 3315 \| HSPB1 \| DISEASES 27128 \| CYTH4 \| DISEASES 3976 \| LIF \| DISEASES 968 \| CD68 \| DISEASES 6351 \| CCL4 \| DISEASES 3630 \| INS \| DISEASES 11026 \| LILRA3 \| DISEASES 4277 \| MICB \| DISEASES 348 \| APOE \| DISEASES 1463 \| NCAN \| DISEASES 2056 \| EPO \| DISEASES 54795 \| TRPM4 \| DISEASES 2670 \| GFAP \| DISEASES 6627 \| SNRPA1 \| DISEASES 3958 \| LGALS3 \| DISEASES 6382 \| SDC1 \| DISEASES 182 \| JAG1 \| DISEASES 1401 \| CRP \| DISEASES 1116 \| CHI3L1 \| DISEASES 10752 \| CHL1 \| DISEASES 9398 \| CD101 \| DISEASES 5156 \| PDGFRA \| DISEASES 301 \| ANXA1 \| DISEASES 8638 \| OASL \| DISEASES 60468 \| BACH2 \| DISEASES 4907 \| NT5E \| DISEASES 1329 \| COX5B \| DISEASES 55501 \| CHST12 \| DISEASES 3569 \| IL6 \| DISEASES 6426 \| SRSF1 \| DISEASES 3557 \| IL1RN \| DISEASES 2572 \| GAD2 \| DISEASES 27348 \| TOR1B \| DISEASES 5168 \| ENPP2 \| DISEASES 6366 \| CCL21 \| DISEASES 10850 \| CCL27 \| DISEASES 971 \| CD72 \| DISEASES 8737 \| RIPK1 \| DISEASES 3134 \| HLA-F \| DISEASES 7097 \| TLR2 \| DISEASES 91351 \| DDX60L \| DISEASES 4316 \| MMP7 \| DISEASES 64066 \| MMP27 \| DISEASES 2581 \| GALC \| DISEASES 4001 \| LMNB1 \| DISEASES 6095 \| RORA \| DISEASES 23495 \| TNFRSF13B \| DISEASES 8669 \| EIF3J \| DISEASES 8482 \| SEMA7A \| DISEASES 54947 \| LPCAT2 \| DISEASES 8731 \| RNMT \| DISEASES 7728 \| ZNF175 \| DISEASES 7305 \| TYROBP \| DISEASES 5465 \| PPARA \| DISEASES 7077 \| TIMP2 \| DISEASES 25939 \| SAMHD1 \| DISEASES 3783 \| KCNN4 \| DISEASES 5595 \| MAPK3 \| DISEASES 6855 \| SYP \| DISEASES 2033 \| EP300 \| DISEASES 3552 \| IL1A \| DISEASES 3553 \| IL1B \| DISEASES 9466 \| IL27RA \| DISEASES 55723 \| ASF1B \| DISEASES 4854 \| NOTCH3 \| DISEASES 3977 \| LIFR \| DISEASES 64135 \| IFIH1 \| DISEASES 6403 \| SELP \| DISEASES 7301 \| TYRO3 \| DISEASES 51101 \| ZC2HC1A \| DISEASES 3574 \| IL7 \| DISEASES 23095 \| KIF1B \| DISEASES 9262 \| STK17B \| DISEASES 4162 \| MCAM \| DISEASES 10382 \| TUBB4A \| DISEASES 868 \| CBLB \| DISEASES 1615 \| DARS \| DISEASES 4811 \| NID1 \| DISEASES 941 \| CD80 \| DISEASES 2892 \| GRIA3 \| DISEASES 1421 \| CRYGD \| DISEASES 2247 \| FGF2 \| DISEASES 3004 \| GZMM \| DISEASES 3589 \| IL11 \| DISEASES 8506 \| CNTNAP1 \| DISEASES 6774 \| STAT3 \| DISEASES 5443 \| POMC \| DISEASES 7297 \| TYK2 \| DISEASES 3383 \| ICAM1 \| DISEASES 7535 \| ZAP70 \| DISEASES 11343 \| MGLL \| DISEASES 1462 \| VCAN \| DISEASES 6507 \| SLC1A3 \| DISEASES 1950 \| EGF \| DISEASES 51247 \| PAIP2 \| DISEASES 64374 \| SIL1 \| DISEASES 10371 \| SEMA3A \| DISEASES 8829 \| NRP1 \| DISEASES 1390 \| CREM \| DISEASES 55749 \| CCAR1 \| DISEASES 10180 \| RBM6 \| DISEASES 939 \| CD27 \| DISEASES 5371 \| PML \| DISEASES 3687 \| ITGAX \| DISEASES 1039 \| CDR2 \| DISEASES 3394 \| IRF8 \| DISEASES 6687 \| SPG7 \| DISEASES 10140 \| TOB1 \| DISEASES 7157 \| TP53 \| DISEASES 7596 \| ZNF45 \| DISEASES 3454 \| IFNAR1 \| DISEASES 207 \| AKT1 \| DISEASES 11006 \| LILRB4 \| DISEASES 5141 \| PDE4A \| DISEASES 2854 \| GPR32 \| DISEASES 8547 \| FCN3 \| DISEASES 2212 \| FCGR2A \| DISEASES 10262 \| SF3B4 \| DISEASES 130589 \| GALM \| DISEASES 805 \| CALM2 \| DISEASES 2840 \| GPR17 \| DISEASES 25953 \| PNKD \| DISEASES 8893 \| EIF2B5 \| DISEASES 3578 \| IL9 \| DISEASES 134864 \| TAAR1 \| DISEASES 4841 \| NONO \| DISEASES 8795 \| TNFRSF10B \| DISEASES 1392 \| CRH \| DISEASES 3439 \| IFNA1 \| DISEASES 4915 \| NTRK2 \| DISEASES 4851 \| NOTCH1 \| DISEASES 196743 \| PAOX \| DISEASES 6506 \| SLC1A2 \| DISEASES 90952 \| ESAM \| DISEASES 10666 \| CD226 \| DISEASES 3606 \| IL18 \| DISEASES 23457 \| ABCB9 \| DISEASES 8853 \| ASAP2 \| DISEASES 7082 \| TJP1 \| DISEASES 4249 \| MGAT5 \| DISEASES 2895 \| GRID2 \| DISEASES 5741 \| PTH \| DISEASES 8404 \| SPARCL1 \| DISEASES 2893 \| GRIA4 \| DISEASES 2697 \| GJA1 \| DISEASES 29974 \| A1CF \| DISEASES 2911 \| GRM1 \| DISEASES 6328 \| SCN3A \| DISEASES 6326 \| SCN2A \| DISEASES 925 \| CD8A \| DISEASES 23643 \| LY96 \| DISEASES 351 \| APP \| DISEASES 760 \| CA2 \| DISEASES 83752 \| LONP2 \| DISEASES 1436 \| CSF1R \| DISEASES 10538 \| BATF \| DISEASES 10563 \| CXCL13 \| DISEASES 6750 \| SST \| DISEASES 5468 \| PPARG \| DISEASES 3156 \| HMGCR \| DISEASES 653361 \| NCF1 \| DISEASES 50848 \| F11R \| DISEASES 3460 \| IFNGR2 \| DISEASES 11054 \| OGFR \| DISEASES 11189 \| CELF3 \| DISEASES 1636 \| ACE \| DISEASES 115650 \| TNFRSF13C \| DISEASES 808 \| CALM3 \| DISEASES 6285 \| S100B \| DISEASES 2220 \| FCN2 \| DISEASES 9437 \| NCR1 \| DISEASES 643 \| CXCR5 \| DISEASES 729230 \| CCR2 \| DISEASES 1234 \| CCR5 \| DISEASES 5439 \| POLR2J \| DISEASES 2905 \| GRIN2C \| DISEASES 6352 \| CCL5 \| DISEASES 6777 \| STAT5B \| DISEASES 3060 \| HCRT \| DISEASES 125950 \| RAVER1 \| DISEASES 58191 \| CXCL16 \| DISEASES 10482 \| NXF1 \| DISEASES 178 \| AGL \| DISEASES 7412 \| VCAM1 \| DISEASES 2215 \| FCGR3B \| DISEASES 5966 \| REL \| DISEASES 27306 \| HPGDS \| DISEASES 10461 \| MERTK \| DISEASES 3577 \| CXCR1 \| DISEASES 8320 \| EOMES \| DISEASES 5274 \| SERPINI1 \| DISEASES 213 \| ALB \| DISEASES 57406 \| ABHD6 \| DISEASES 132014 \| IL17RE \| DISEASES 84818 \| IL17RC \| DISEASES 6853 \| SYN1 \| DISEASES 6374 \| CXCL5 \| DISEASES 7123 \| CLEC3B \| DISEASES 1230 \| CCR1 \| DISEASES 5648 \| MASP1 \| DISEASES 8927 \| BSN \| DISEASES 308 \| ANXA5 \| DISEASES 132612 \| ADAD1 \| DISEASES 3600 \| IL15 \| DISEASES 51752 \| ERAP1 \| DISEASES 7098 \| TLR3 \| DISEASES 27242 \| TNFRSF21 \| DISEASES 3562 \| IL3 \| DISEASES 1437 \| CSF2 \| DISEASES 116379 \| IL22RA2 \| DISEASES 6469 \| SHH \| DISEASES 122769 \| LRR1 \| DISEASES 3429 \| IFI27 \| DISEASES 219793 \| TBATA \| DISEASES 5896 \| RAG1 \| DISEASES 4314 \| MMP3 \| DISEASES 290 \| ANPEP \| DISEASES 11318 \| GPR182 \| DISEASES 6778 \| STAT6 \| DISEASES 25895 \| METTL21B \| DISEASES 23582 \| CCNDBP1 \| DISEASES 254240 \| BPIFC \| DISEASES 64127 \| NOD2 \| DISEASES 6240 \| RRM1 \| DISEASES 558 \| AXL \| DISEASES 4909 \| NTF4 \| DISEASES 4054 \| LTBP3 \| DISEASES 27249 \| MMADHC \| DISEASES 5724 \| PTAFR \| DISEASES 719 \| C3AR1 \| DISEASES 5617 \| PRL \| DISEASES 51305 \| KCNK9 \| DISEASES 79058 \| ASPSCR1 \| DISEASES 6356 \| CCL11 \| DISEASES 51082 \| POLR1D \| DISEASES 598 \| BCL2L1 \| DISEASES 3479 \| IGF1 \| DISEASES 10605 \| PAIP1 \| DISEASES 10296 \| MAEA \| DISEASES 5734 \| PTGER4 \| DISEASES 3603 \| IL16 \| DISEASES 3308 \| HSPA4 \| DISEASES 3688 \| ITGB1 \| DISEASES 8988 \| HSPB3 \| DISEASES 6249 \| CLIP1 \| DISEASES 1493 \| CTLA4 \| DISEASES 7857 \| SCG2 \| DISEASES 10663 \| CXCR6 \| DISEASES 136647 \| MPLKIP \| DISEASES 3596 \| IL13 \| DISEASES 5354 \| PLP1 \| DISEASES 1901 \| S1PR1 \| DISEASES 7275 \| TUB \| DISEASES 3627 \| CXCL10 \| DISEASES 214 \| ALCAM \| DISEASES 3575 \| IL7R \| DISEASES 6504 \| SLAMF1 \| DISEASES 2353 \| FOS \| DISEASES 3777 \| KCNK3 \| DISEASES 9331 \| B4GALT6 \| DISEASES 253782 \| CERS6 \| DISEASES 56246 \| MRAP \| DISEASES 6373 \| CXCL11 \| DISEASES 54205 \| CYCS \| DISEASES 11338 \| U2AF2 \| DISEASES 27087 \| B3GAT1 \| DISEASES 2752 \| GLUL \| DISEASES 4323 \| MMP14 \| DISEASES 6363 \| CCL19 \| DISEASES 79608 \| RIC3 \| DISEASES 5340 \| PLG \| DISEASES 5653 \| KLK6 \| DISEASES 1808 \| DPYSL2 \| DISEASES 6868 \| ADAM17 \| DISEASES 947 \| CD34 \| DISEASES 3661 \| IRF3 \| DISEASES 6670 \| SP3 \| DISEASES 83759 \| RBM4B \| DISEASES 9420 \| CYP7B1 \| DISEASES 4118 \| MAL \| DISEASES 836 \| CASP3 \| DISEASES 131450 \| CD200R1 \| DISEASES 358 \| AQP1 \| DISEASES 1240 \| CMKLR1 \| DISEASES 10432 \| RBM14 \| DISEASES 4744 \| NEFH \| DISEASES 84868 \| HAVCR2 \| DISEASES 7351 \| UCP2 \| DISEASES 442578 \| STAG3L3 \| DISEASES 22843 \| PPM1E \| DISEASES 8837 \| CFLAR \| DISEASES 8557 \| TCAP \| DISEASES 3952 \| LEP \| DISEASES 26986 \| PABPC1 \| DISEASES 3184 \| HNRNPD \| DISEASES 4327 \| MMP19 \| DISEASES 8877 \| SPHK1 \| DISEASES 4179 \| CD46 \| DISEASES 10102 \| TSFM \| DISEASES 57101 \| ANO2 \| DISEASES 4234 \| METTL1 \| DISEASES 998 \| CDC42 \| DISEASES 3737 \| KCNA2 \| DISEASES 1831 \| TSC22D3 \| DISEASES 1191 \| CLU \| DISEASES 30835 \| CD209 \| DISEASES 23075 \| SWAP70 \| DISEASES 6773 \| STAT2 \| DISEASES 10859 \| LILRB1 \| DISEASES 4261 \| CIITA \| DISEASES 1604 \| CD55 \| DISEASES 8560 \| DEGS1 \| DISEASES 57381 \| RHOJ \| DISEASES 5551 \| PRF1 \| DISEASES 4684 \| NCAM1 \| DISEASES 7173 \| TPO \| DISEASES 10992 \| SF3B2 \| DISEASES 3579 \| CXCR2 \| DISEASES 1728 \| NQO1 \| DISEASES 80381 \| CD276 \| DISEASES 285195 \| SLC9A9 \| DISEASES 6683 \| SPAST \| DISEASES 23765 \| IL17RA \| DISEASES 6863 \| TAC1 \| DISEASES 6888 \| TALDO1 \| DISEASES 149233 \| IL23R \| DISEASES 162282 \| ANKFN1 \| DISEASES 3039 \| HBA1 \| DISEASES 246330 \| PELI3 \| DISEASES 4312 \| MMP1 \| DISEASES 5932 \| RBBP8 \| DISEASES 923 \| CD6 \| DISEASES 491 \| ATP2B2 \| DISEASES 84260 \| TCHP \| DISEASES 5241 \| PGR \| DISEASES 1272 \| CNTN1 \| DISEASES 3326 \| HSP90AB1 \| DISEASES 55254 \| TMEM39A \| DISEASES 9622 \| KLK4 \| DISEASES 89849 \| ATG16L2 \| DISEASES 55191 \| NADSYN1 \| DISEASES 1237 \| CCR8 \| DISEASES 51330 \| TNFRSF12A \| DISEASES 6097 \| RORC \| DISEASES 4094 \| MAF \| DISEASES 146722 \| CD300LF \| DISEASES 4843 \| NOS2 \| DISEASES 4661 \| MYT1 \| DISEASES 1435 \| CSF1 \| DISEASES 3563 \| IL3RA \| DISEASES 8784 \| TNFRSF18 \| DISEASES 53637 \| S1PR5 \| DISEASES 23046 \| KIF21B \| DISEASES 3739 \| KCNA4 \| DISEASES 706 \| TSPO \| DISEASES 83733 \| SLC25A18 \| DISEASES 50616 \| IL22 \| DISEASES 3665 \| IRF7 \| DISEASES 8651 \| SOCS1 \| DISEASES 8224 \| SYN3 \| DISEASES 842 \| CASP9 \| DISEASES 9021 \| SOCS3 \| DISEASES 28955 \| DEXI \| DISEASES 6900 \| CNTN2 \| DISEASES 10215 \| OLIG2 \| DISEASES 63827 \| BCAN \| DISEASES 90134 \| KCNH7 \| DISEASES 6401 \| SELE \| DISEASES 2621 \| GAS6 \| DISEASES 942 \| CD86 \| DISEASES 79582 \| SPAG16 \| DISEASES 124976 \| SPNS2 \| DISEASES 3916 \| LAMP1 \| DISEASES 4600 \| MX2 \| DISEASES 682 \| BSG \| DISEASES 151888 \| BTLA \| DISEASES 57178 \| ZMIZ1 \| DISEASES 140890 \| SREK1 \| DISEASES 120227 \| CYP2R1 \| DISEASES 5133 \| PDCD1 \| DISEASES 3320 \| HSP90AA1 \| DISEASES 349667 \| RTN4RL2 \| DISEASES 135 \| ADORA2A \| DISEASES 3802 \| KIR2DL1 \| DISEASES 3988 \| LIPA \| DISEASES 114548 \| NLRP3 \| DISEASES 112744 \| IL17F \| DISEASES 1641 \| DCX \| DISEASES 64386 \| MMP25 \| DISEASES 3932 \| LCK \| DISEASES 57142 \| RTN4 \| DISEASES 50615 \| IL21R \| DISEASES 554 \| AVPR2 \| DISEASES 3824 \| KLRD1 \| DISEASES 3185 \| HNRNPF \| DISEASES 23583 \| SMUG1 \| DISEASES 3572 \| IL6ST \| DISEASES 51634 \| RBMX2 \| DISEASES 857 \| CAV1 \| DISEASES 5329 \| PLAUR \| DISEASES 29894 \| CPSF1 \| DISEASES 3117 \| HLA-DQA1 \| DISEASES 8835 \| SOCS2 \| DISEASES 163059 \| ZNF433 \| DISEASES 3329 \| HSPD1 \| DISEASES 222236 \| NAPEPLD \| DISEASES 10249 \| GLYAT \| DISEASES 966 \| CD59 \| DISEASES 6932 \| TCF7 \| DISEASES 4137 \| MAPT \| DISEASES 6614 \| SIGLEC1 \| DISEASES 6776 \| STAT5A \| DISEASES 29087 \| THYN1 \| DISEASES 128853 \| DUSP15 \| DISEASES 3178 \| HNRNPA1 \| DISEASES 1508 \| CTSB \| DISEASES 342897 \| NCCRP1 \| DISEASES 259197 \| NCR3 \| DISEASES 4939 \| OAS2 \| DISEASES 79722 \| ANKRD55 \| DISEASES 2537 \| IFI6 \| DISEASES 921 \| CD5 \| DISEASES 3716 \| JAK1 \| DISEASES 8741 \| TNFSF13 \| DISEASES 2100 \| ESR2 \| DISEASES 1003 \| CDH5 \| DISEASES 3605 \| IL17A \| DISEASES 1499 \| CTNNB1 \| DISEASES 4929 \| NR4A2 \| DISEASES 23114 \| NFASC \| DISEASES 347 \| APOD \| DISEASES 1861 \| TOR1A \| DISEASES 1811 \| SLC26A3 \| DISEASES 6334 \| SCN8A \| DISEASES 2534 \| FYN \| DISEASES 3181 \| HNRNPA2B1 \| DISEASES 65251 \| ZNF649 \| DISEASES 8654 \| PDE5A \| DISEASES 64218 \| SEMA4A \| DISEASES 728 \| C5AR1 \| DISEASES 100506658 \| OCLN \| DISEASES 84894 \| LINGO1 \| DISEASES 1785 \| DNM2 \| DISEASES 160364 \| CLEC12A \| DISEASES 355 \| FAS \| DISEASES 3240 \| HP \| DISEASES 140885 \| SIRPA \| DISEASES 23154 \| NCDN \| DISEASES 3476 \| IGBP1 \| DISEASES 10507 \| SEMA4D \| DISEASES 1822 \| ATN1 \| DISEASES 3187 \| HNRNPH1 \| DISEASES 3683 \| ITGAL \| DISEASES 3084 \| NRG1 \| DISEASES 8794 \| TNFRSF10C \| DISEASES 246778 \| IL27 \| DISEASES 5725 \| PTBP1 \| DISEASES 801 \| CALM1 \| DISEASES 1996 \| ELAVL4 \| DISEASES 3663 \| IRF5 \| DISEASES 60 \| ACTB \| DISEASES 148867 \| SLC30A7 \| DISEASES 337 \| APOA4 \| DISEASES 340784 \| HMX3 \| DISEASES 2764 \| GMFB \| DISEASES 1903 \| S1PR3 \| DISEASES 6714 \| SRC \| DISEASES 1524 \| CX3CR1 \| DISEASES 6775 \| STAT4 \| DISEASES 841 \| CASP8 \| DISEASES 2213 \| FCGR2B \| DISEASES 112476 \| PRRT2 \| DISEASES 6364 \| CCL20 \| DISEASES 3821 \| KLRC1 \| DISEASES 9332 \| CD163 \| DISEASES 5294 \| PIK3CG \| DISEASES 5602 \| MAPK10 \| DISEASES 1995 \| ELAVL3 \| DISEASES 23607 \| CD2AP \| DISEASES 753 \| LDLRAD4 \| DISEASES 8645 \| KCNK5 \| DISEASES 26191 \| PTPN22 \| DISEASES 4641 \| MYO1C \| DISEASES 4192 \| MDK \| DISEASES 6427 \| SRSF2 \| DISEASES 51150 \| SDF4 \| DISEASES 3123 \| HLA-DRB1 \| DISEASES 79947 \| DHDDS \| DISEASES 7037 \| TFRC \| DISEASES 3135 \| HLA-G \| DISEASES 5599 \| MAPK8 \| DISEASES 170482 \| CLEC4C \| DISEASES 4133 \| MAP2 \| DISEASES 1803 \| DPP4 \| DISEASES 6241 \| RRM2 \| DISEASES 11076 \| TPPP \| DISEASES 1565 \| CYP2D6 \| DISEASES 54106 \| TLR9 \| DISEASES 6663 \| SOX10 \| DISEASES 58484 \| NLRC4 \| DISEASES 6772 \| STAT1 \| DISEASES 26047 \| CNTNAP2 \| DISEASES 2705 \| GJB1 \| DISEASES 4283 \| CXCL9 \| DISEASES 7096 \| TLR1 \| DISEASES 4538 \| MT-ND4 \| DISEASES 4536 \| MT-ND2 \| DISEASES 55157 \| DARS2 \| DISEASES 2913 \| GRM3 \| DISEASES 23038 \| WDTC1 \| DISEASES 7052 \| TGM2 \| DISEASES 961 \| CD47 \| DISEASES 1270 \| CNTF \| DISEASES 29948 \| OSGIN1 \| DISEASES 163882 \| CNST \| DISEASES 23596 \| OPN3 \| DISEASES 4548 \| MTR \| DISEASES 5867 \| RAB4A \| DISEASES 57165 \| GJC2 \| DISEASES 142 \| PARP1 \| DISEASES 2058 \| EPRS \| DISEASES 7042 \| TGFB2 \| DISEASES 3664 \| IRF6 \| DISEASES 1378 \| CR1 \| DISEASES 117289 \| TAGAP \| DISEASES 1118 \| CHIT1 \| DISEASES 7432 \| VIP \| DISEASES 9283 \| GPR37L1 \| DISEASES 5788 \| PTPRC \| DISEASES 5996 \| RGS1 \| DISEASES 5321 \| PLA2G4A \| DISEASES 5743 \| PTGS2 \| DISEASES 6004 \| RGS16 \| DISEASES 356 \| FASLG \| DISEASES 3459 \| IFNGR1 \| DISEASES 6375 \| XCL1 \| DISEASES 127943 \| FCRLB \| DISEASES 2214 \| FCGR3A \| DISEASES 383 \| ARG1 \| DISEASES 3766 \| KCNJ10 \| DISEASES 9447 \| AIM2 \| DISEASES 913 \| CD1E \| DISEASES 911 \| CD1C \| DISEASES 912 \| CD1D \| DISEASES 115352 \| FCRL3 \| DISEASES 10763 \| NES \| DISEASES 2173 \| FABP7 \| DISEASES 3570 \| IL6R \| DISEASES 6280 \| S100A9 \| DISEASES 4942 \| OAT \| DISEASES 262 \| AMD1 \| DISEASES 1520 \| CTSS \| DISEASES 7073 \| TIAL1 \| DISEASES 6001 \| RGS10 \| DISEASES 8349 \| HIST2H2BE \| DISEASES 2209 \| FCGR1A \| DISEASES 914 \| CD2 \| DISEASES 965 \| CD58 \| DISEASES 1268 \| CNR1 \| DISEASES 4803 \| NGF \| DISEASES 8266 \| UBL4A \| DISEASES 9446 \| GSTO1 \| DISEASES 1117 \| CHI3L2 \| DISEASES 3738 \| KCNA3 \| DISEASES 64783 \| RBM15 \| DISEASES 388650 \| FAM69A \| DISEASES 6125 \| RPL5 \| DISEASES 7813 \| EVI5 \| DISEASES 1369 \| CPN1 \| DISEASES 2633 \| GBP1 \| DISEASES 2959 \| GTF2B \| DISEASES 1038 \| CDR1 \| DISEASES 2258 \| FGF13 \| DISEASES 959 \| CD40LG \| DISEASES 10964 \| IFI44L \| DISEASES 5223 \| PGAM1 \| DISEASES 55225 \| RAVER2 \| DISEASES 93377 \| OPALIN \| DISEASES 953 \| ENTPD1 \| DISEASES 3725 \| JUN \| DISEASES 9481 \| SLC25A27 \| DISEASES 774 \| CACNA1B \| DISEASES 5730 \| PTGDS \| DISEASES 138307 \| LCN8 \| DISEASES 3434 \| IFIT1 \| DISEASES 2219 \| FCN1 \| DISEASES 3433 \| IFIT2 \| DISEASES 9023 \| CH25H \| DISEASES 7422 \| VEGFA \| DISEASES 958 \| CD40 \| DISEASES 4318 \| MMP9 \| DISEASES 6709 \| SPTAN1 \| DISEASES 3188 \| HNRNPH2 \| DISEASES 100 \| ADA \| DISEASES 4725 \| NDUFS5 \| DISEASES 27286 \| SRPX2 \| DISEASES 9436 \| NCR2 \| DISEASES 54209 \| TREM2 \| DISEASES 8879 \| SGPL1 \| DISEASES 1979 \| EIF4EBP2 \| DISEASES 1025 \| CDK9 \| DISEASES 2833 \| CXCR3 \| DISEASES 2170 \| FABP3 \| DISEASES 6429 \| SRSF4 \| DISEASES 2934 \| GSN \| DISEASES 4153 \| MBL2 \| DISEASES 7099 \| TLR4 \| DISEASES 2827 \| GPR3 \| DISEASES 2914 \| GRM4 \| DISEASES 1043 \| CD52 \| DISEASES 240 \| ALOX5 \| DISEASES 1269 \| CNR2 \| DISEASES 1896 \| EDA \| DISEASES 10236 \| HNRNPR \| DISEASES 8518 \| IKBKAP \| DISEASES 55335 \| NIPSNAP3B \| DISEASES 3108 \| HLA-DMA \| DISEASES 5698 \| PSMB9 \| DISEASES 3118 \| HLA-DQA2 \| DISEASES 3127 \| HLA-DRB5 \| DISEASES 7046 \| TGFBR1 \| DISEASES 4855 \| NOTCH4 \| DISEASES 55357 \| TBC1D2 \| DISEASES 5320 \| PLA2G2A \| DISEASES 4814 \| NINJ1 \| DISEASES 23569 \| PADI4 \| DISEASES 51702 \| PADI3 \| DISEASES 29943 \| PADI1 \| DISEASES 11240 \| PADI2 \| DISEASES 3303 \| HSPA1A \| DISEASES 3305 \| HSPA1L \| DISEASES 6850 \| SYK \| DISEASES 23013 \| SPEN \| DISEASES 3055 \| HCK \| DISEASES 10673 \| TNFSF13B \| DISEASES 199 \| AIF1 \| DISEASES 4795 \| NFKBIL1 \| DISEASES 50943 \| FOXP3 \| DISEASES 100507436 \| MICA \| DISEASES 3107 \| HLA-C \| DISEASES 7133 \| TNFRSF1B \| DISEASES 1041 \| CDSN \| DISEASES 1880 \| GPR183 \| DISEASES 4524 \| MTHFR \| DISEASES 3133 \| HLA-E \| DISEASES 11074 \| TRIM31 \| DISEASES 3105 \| HLA-A \| DISEASES 4340 \| MOG \| DISEASES 1471 \| CST3 \| DISEASES 6723 \| SRM \| DISEASES 1325 \| CORT \| DISEASES 2262 \| GPC5 \| DISEASES 4821 \| NKX2-2 \| DISEASES 5457 \| POU4F1 \| DISEASES 3274 \| HRH2 \| DISEASES 7536 \| SF1 \| DISEASES 3604 \| TNFRSF9 \| DISEASES 1804 \| DPP6 \| DISEASES 8718 \| TNFRSF25 \| DISEASES 57623 \| ZFAT \| DISEASES 6873 \| TAF2 \| DISEASES 79258 \| MMEL1 \| DISEASES 388585 \| HES5 \| DISEASES 6354 \| CCL7 \| DISEASES 8559 \| PRPF18 \| DISEASES 1536 \| CYBB \| DISEASES 1114 \| CHGB \| DISEASES 9308 \| CD83 \| DISEASES 7293 \| TNFRSF4 \| DISEASES 2625 \| GATA3 \| DISEASES 5251 \| PHEX \| DISEASES 1906 \| EDN1 \| DISEASES 9636 \| ISG15 \| DISEASES 23586 \| DDX58 \| DISEASES 3559 \| IL2RA \| DISEASES 10346 \| TRIM22 \| DISEASES 85363 \| TRIM5 \| DISEASES 9365 \| KL \| DISEASES 1993 \| ELAVL2 \| DISEASES 3440 \| IFNA2 \| DISEASES 3449 \| IFNA16 \| DISEASES 3448 \| IFNA14 \| DISEASES 3456 \| IFNB1 \| DISEASES 7114 \| TMSB4X \| DISEASES 51284 \| TLR7 \| DISEASES 3662 \| IRF4 \| DISEASES 55858 \| TMEM165 \| DISEASES 90865 \| IL33 \| DISEASES 29126 \| CD274 \| DISEASES 3717 \| JAK2 \| DISEASES 9751 \| SNPH \| DISEASES 55321 \| TMEM74B \| DISEASES 3822 \| KLRC2 \| DISEASES 91543 \| RSAD2 \| DISEASES 55504 \| TNFRSF19 \| DISEASES 116448 \| OLIG1 \| DISEASES 3736 \| KCNA1 \| DISEASES 4155 \| MBP \| DISEASES 361 \| AQP4 \| DISEASES 4336 \| MOBP \| DISEASES 130074 \| FAM168B \| DISEASES 338442 \| HCAR2 \| DISEASES 3811 \| KIR3DL1 \| DISEASES 10288 \| LILRB2 \| DISEASES 11100 \| HNRNPUL1 \| DISEASES 4099 \| MAG \| DISEASES 9047 \| SH2D2A \| DISEASES 9244 \| CRLF1 \| DISEASES 338773 \| TMEM119 \| DISEASES 5450 \| POU2AF1 \| DISEASES 5803 \| PTPRZ1 \| DISEASES 2596 \| GAP43 \| DISEASES 1267 \| CNP \| DISEASES 5091 \| PC \| DISEASES 26130 \| GAPVD1 \| DISEASES 5627 \| PROS1 \| DISEASES 9560 \| CCL4L2 \| DISEASES 6355 \| CCL8 \| DISEASES 6696 \| SPP1 \| DISEASES 1365 \| CLDN3 \| DISEASES 3122 \| HLA-DRA \| DISEASES 3965 \| LGALS9 \| DISEASES 2919 \| CXCL1 \| DISEASES 6387 \| CXCL12 \| DISEASES 27327 \| TNRC6A \| DISEASES 831 \| CAST \| DISEASES 6489 \| ST8SIA1 \| DISEASES 3676 \| ITGA4 \| DISEASES 4780 \| NFE2L2 \| DISEASES 80380 \| PDCD1LG2 \| DISEASES 594857 \| NPS \| DISEASES 51020 \| HDDC2 \| DISEASES 4599 \| MX1 \| DISEASES 3119 \| HLA-DQB1 \| DISEASES 56948 \| SDR39U1 \| DISEASES 7442 \| TRPV1 \| DISEASES 440836 \| ODF3B \| DISEASES 3803 \| KIR2DL2 \| DISEASES 10747 \| MASP2 \| DISEASES 29951 \| PDZRN4 \| DISEASES 23308 \| ICOSLG \| DISEASES 7122 \| CLDN5 \| DISEASES 7514 \| XPO1 \| DISEASES 51571 \| FAM49B \| DISEASES 10437 \| IFI30 \| DISEASES 1994 \| ELAVL1 \| DISEASES 5150 \| PDE7A \| DISEASES 6611 \| SMS \| DISEASES 7018 \| TF \| DISEASES 10636 \| RGS14 \| DISEASES 642636 \| RAD21L1 \| DISEASES 6295 \| SAG \| DISEASES 29072 \| SETD2 \| DISEASES 7852 \| CXCR4 \| DISEASES 23274 \| CLEC16A \| DISEASES 501 \| ALDH7A1 \| DISEASES 3267 \| AGFG1 \| DISEASES 1385 \| CREB1 \| DISEASES 10062 \| NR1H3 \| DISEASES 4938 \| OAS1 \| DISEASES 3384 \| ICAM2 \| DISEASES 10659 \| CELF2 \| DISEASES 3120 \| HLA-DQB2 \| DISEASES 10478 \| SLC25A17 \| DISEASES 5777 \| PTPN6 \| DISEASES 2086 \| ERV3-1 \| DISEASES 389362 \| PSMG4 \| DISEASES 10553 \| HTATIP2 \| DISEASES 146713 \| RBFOX3 \| DISEASES 8399 \| PLA2G10 \| DISEASES 197 \| AHSG \| DISEASES 720 \| C4A \| DISEASES 90874 \| ZNF697 \| DISEASES 2898 \| GRIK2 \| DISEASES 4908 \| NTF3 \| DISEASES 960 \| CD44 \| DISEASES 7124 \| TNF \| DISEASES 3109 \| HLA-DMB \| DISEASES 3106 \| HLA-B \| DISEASES 387 \| RHOA \| DISEASES 7072 \| TIA1 \| DISEASES 4615 \| MYD88 \| DISEASES 3594 \| IL12RB1 \| DISEASES 4049 \| LTA \| DISEASES 388372 \| CCL4L1 \| DISEASES 139728 \| PNCK \| DISEASES 3115 \| HLA-DPB1 \| DISEASES 390748 \| PABPN1L \| DISEASES 5578 \| PRKCA \| DISEASES 3798 \| KIF5A \| DISEASES 2668 \| GDNF \| DISEASES 1154 \| CISH \| DISEASES 408 \| ARRB1 \| DISEASES 834 \| CASP1 \| DISEASES 4050 \| LTB \| DISEASES 4140 \| MARK3 \| DISEASES 116 \| ADCYAP1 \| DISEASES 3451 \| IFNA17 \| DISEASES 3586 \| IL10 \| DISEASES 58155 \| PTBP2 \| DISEASES 627 \| BDNF \| DISEASES 133396 \| IL31RA \| DISEASES 1967 \| EIF2B1 \| DISEASES 9749 \| PHACTR2 \| DISEASES 29803 \| REPIN1 \| DISEASES 57620 \| STIM2 \| DISEASES 338376 \| IFNE \| DISEASES 80007 \| C10orf88 \| DISEASES 26137 \| ZBTB20 \| DISEASES 30816 \| ERVW-1 \| DISEASES 4345 \| CD200 \| DISEASES 8530 \| CST7 \| DISEASES 5542 \| PRB1 \| DISEASES 6949 \| TCOF1 \| DISEASES 2638 \| GC \| DISEASES 51428 \| DDX41 \| DISEASES 11275 \| KLHL2 \| DISEASES 5238 \| PGM3 \| DISEASES 2920 \| CXCL2 \| DISEASES 345611 \| IRGM \| DISEASES 51312 \| SLC25A37 \| DISEASES 440695 \| ETV3L \| DISEASES 3620 \| IDO1 \| DISEASES 4914 \| NTRK1 \| DISEASES 84000 \| TMPRSS13 \| DISEASES 84364 \| ARFGAP2 \| DISEASES 10658 \| CELF1 \| DISEASES 930 \| CD19 \| DISEASES 1232 \| CCR3 \| DISEASES 3684 \| ITGAM \| DISEASES 5027 \| P2RX7 \| DISEASES 146227 \| BEAN1 \| DISEASES 4850 \| CNOT4 \| DISEASES 10198 \| MPHOSPH9 \| DISEASES 115704 \| EVI5L \| DISEASES 11153 \| FICD \| DISEASES 7421 \| VDR \| DISEASES 8972 \| MGAM \| DISEASES 8742 \| TNFSF12 \| DISEASES 4157 \| MC1R \| DISEASES 56963 \| RGMA \| DISEASES 567 \| B2M \| DISEASES 101 \| ADAM8 \| DISEASES 3316 \| HSPB2 \| DISEASES 22861 \| NLRP1 \| DISEASES 4782 \| NFIC \| DISEASES 9294 \| S1PR2 \| DISEASES 4701 \| NDUFA7 \| DISEASES 6689 \| SPIB \| DISEASES 7409 \| VAV1 \| DISEASES 54435 \| HCG4 \| DISEASES 102723508 \| KANTR \| DISEASES 100885779 \| LINC-ROR \| DISEASES 348120 \| LINC01193 \| DISEASES 677777 \| SCARNA12 \| DISEASES 677765 \| SCARNA18 \| DISEASES 116937 \| SNORD83A \| DISEASES 692225 \| SNORD94 \| DISEASES
Locus	(Waiting for update.)

Disease ID	280
Disease	multiple sclerosis
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:204) HP:0012378 \| Fatigue \| 130 HP:0100543 \| Cognitive deficits \| 80 HP:0001257 \| Spasticity \| 61 HP:0000716 \| Depression \| 55 HP:0012531 \| Pain \| 40 HP:0100653 \| Optic neuritis \| 39 HP:0005293 \| Venous insufficiency \| 32 HP:0002180 \| Neurodegeneration \| 25 HP:0002527 \| Falls \| 25 HP:0011096 \| Demyelination \| 21 HP:0002352 \| Leukoencephalopathy \| 20 HP:0002960 \| Autoimmune condition \| 18 HP:0100661 \| Trigeminal neuralgia \| 14 HP:0000554 \| Uveitis \| 12 HP:0000739 \| Anxiety \| 12 HP:0012444 \| Brain wasting \| 11 HP:0001337 \| Tremor \| 10 HP:0002354 \| Memory loss \| 10 HP:0002459 \| Dysautonomia \| 10 HP:0002383 \| Encephalitis \| 9 HP:0012043 \| Pendular nystagmus \| 9 HP:0002015 \| Swallowing difficulty \| 8 HP:0000639 \| Nystagmus \| 8 HP:0002315 \| Headaches \| 7 HP:0012115 \| Liver inflammation \| 7 HP:0012124 \| Intermediate uveitis \| 6 HP:0001288 \| Gait disturbance \| 6 HP:0002120 \| Cerebral cortical atrophy \| 6 HP:0000726 \| Dementia \| 6 HP:0040078 \| Axonal degeneration \| 6 HP:0010535 \| Sleep apnea \| 6 HP:0002104 \| Absence of spontaneous respiration \| 6 HP:0002076 \| Migraine headaches \| 5 HP:0100561 \| Spinal cord lesion \| 5 HP:0002360 \| Sleep disturbance \| 5 HP:0100022 \| Movement disorder \| 5 HP:0000708 \| Behavioral problems \| 5 HP:0012532 \| Chronic pain \| 4 HP:0002633 \| Vasculitis \| 4 HP:0003765 \| Psoriasis \| 4 HP:0001297 \| Cerebral vascular events \| 4 HP:0000011 \| Neurogenic bladder \| 4 HP:0001369 \| Arthritis \| 4 HP:0002870 \| Obstructive sleep apnea \| 4 HP:0001250 \| Seizures \| 4 HP:0001903 \| Anemia \| 3 HP:0001268 \| Mental deterioration \| 3 HP:0000709 \| Psychosis \| 3 HP:0001300 \| Parkinsonism \| 3 HP:0000602 \| Ophthalmoplegia \| 3 HP:0004349 \| Reduced bone mineral density \| 3 HP:0012486 \| Inflammation of spinal cord \| 3 HP:0000939 \| Osteoporosis \| 3 HP:0000505 \| Poor vision \| 3 HP:0003447 \| Axonal loss \| 3 HP:0000802 \| Erectile dysfunction \| 3 HP:0002664 \| Neoplasia \| 3 HP:0001251 \| Ataxia \| 3 HP:0012393 \| Allergy \| 3 HP:0000969 \| Dropsy \| 3 HP:0003470 \| Inability to move \| 2 HP:0003613 \| Antiphospholipid antibodies \| 2 HP:0012191 \| B-cell lymphoma \| 2 HP:0007371 \| Atrophy/Degeneration of the corpus callosum \| 2 HP:0000010 \| Frequent urinary tract infections \| 2 HP:0002059 \| Degeneration of cerebrum \| 2 HP:0030217 \| Limb apraxia \| 2 HP:0012452 \| Restless legs \| 2 HP:0000083 \| Renal insufficiency \| 2 HP:0000501 \| Glaucoma \| 2 HP:0001260 \| Dysarthric speech \| 2 HP:0000365 \| Hearing impairment \| 2 HP:0007302 \| Bipolar disorder \| 2 HP:0000722 \| Obsessive compulsive disorder \| 2 HP:0001658 \| Myocardial infarction \| 2 HP:0200136 \| Oral-pharyngeal dysphagia \| 2 HP:0002186 \| Apraxia \| 2 HP:0000496 \| Ocular movement abnormalities \| 2 HP:0002099 \| Asthma \| 2 HP:0002665 \| Lymphoma \| 2 HP:0009027 \| Foot drop \| 2 HP:0002608 \| Celiac disease \| 2 HP:0100598 \| Pulmonary oedema \| 2 HP:0003202 \| Neurogenic muscle atrophy, especially in the lower limbs \| 2 HP:0001649 \| Tachycardia \| 2 HP:0000572 \| Visual loss \| 2 HP:0001513 \| Obesity \| 2 HP:0000020 \| Bladder incontinence \| 2 HP:0002529 \| Neuronal loss in central nervous system \| 2 HP:0002411 \| Myokymia \| 2 HP:0200123 \| Chronic liver inflammation \| 1 HP:0002445 \| Paralysis of all four limbs \| 1 HP:0001635 \| Congestive heart failure \| 1 HP:0001291 \| Cranial nerve disease \| 1 HP:0002955 \| Granulomatosis \| 1 HP:0001094 \| Iridocyclitis \| 1 HP:0000979 \| Purpura \| 1 HP:0030665 \| Holmes' tremor \| 1 HP:0012432 \| Chronic fatigue \| 1 HP:0003560 \| Muscular dystrophy \| 1 HP:0100753 \| Schizophrenia \| 1 HP:0000407 \| sensorineural hearing loss \| 1 HP:0011856 \| Pica \| 1 HP:0011986 \| Ectopic bone formation \| 1 HP:0000017 \| Nocturia \| 1 HP:0030127 \| Endometriosis \| 1 HP:0002487 \| Muscle spasms \| 1 HP:0004757 \| Paroxysmal atrial fibrillation \| 1 HP:0003419 \| Low back pain \| 1 HP:0003472 \| Hypocalcemic tetany \| 1 HP:0002171 \| Cerebral gliosis \| 1 HP:0002135 \| Basal ganglia calcification \| 1 HP:0001370 \| Rheumatoid arthritis \| 1 HP:0100242 \| Sarcoma \| 1 HP:0012302 \| Herpes simplex encephalitis \| 1 HP:0012508 \| Metamorphopsia \| 1 HP:0002346 \| Head tremor \| 1 HP:0002061 \| Lower limb spasticity \| 1 HP:0030773 \| Internuclear ophthalmoplegia \| 1 HP:0001945 \| Fever \| 1 HP:0000622 \| Blurred vision \| 1 HP:0012735 \| Coughing \| 1 HP:0002196 \| Myelopathy \| 1 HP:0010885 \| Aseptic necrosis \| 1 HP:0002607 \| Anal incontinence \| 1 HP:0000317 \| Involuntary facial contraction \| 1 HP:0000590 \| Progressive external ophthalmoplegia \| 1 HP:0012234 \| Agranulocytosis \| 1 HP:0001909 \| Leukemia \| 1 HP:0100512 \| Vitamin D deficiency \| 1 HP:0003418 \| Back pain \| 1 HP:0012173 \| Postural tachycardia \| 1 HP:0000518 \| Cataract \| 1 HP:0100843 \| Glioblastoma \| 1 HP:0030014 \| Female sexual dysfunction \| 1 HP:0000789 \| Infertility \| 1 HP:0005110 \| Atrial fibrillation \| 1 HP:0100033 \| Tic disorder \| 1 HP:0002500 \| Leukoaraiosis \| 1 HP:0010783 \| Erythema \| 1 HP:0000741 \| Apathy \| 1 HP:0001915 \| Aplastic anemia \| 1 HP:0030692 \| Brain tumor \| 1 HP:0002133 \| Status epilepticus \| 1 HP:0040182 \| Inappropriate sinus tachycardia \| 1 HP:0002958 \| Immune dysregulation \| 1 HP:0100785 \| Insomnia \| 1 HP:0004836 \| Acute promyelocytic leukemia \| 1 HP:0012151 \| Hemothorax \| 1 HP:0000725 \| Psychotic episodes \| 1 HP:0000833 \| Glucose intolerance \| 1 HP:0004936 \| Blood clot in vein \| 1 HP:0000016 \| Urinary retention \| 1 HP:0001332 \| Dystonia \| 1 HP:0012461 \| Bacteria in urine \| 1 HP:0000544 \| CPEO \| 1 HP:0003002 \| Breast carcinoma \| 1 HP:0000820 \| Thyroid abnormality \| 1 HP:0000100 \| Nephrosis \| 1 HP:0001317 \| Abnormality of the cerebellum \| 1 HP:0000821 \| Underactive thyroid \| 1 HP:0012721 \| Venous malformations \| 1 HP:0030329 \| Retinal thinning \| 1 HP:0002385 \| Paraparesis \| 1 HP:0100279 \| Ulcerative colitis \| 1 HP:0100327 \| Cow milk allergy \| 1 HP:0005202 \| Helicobacter pylori infection \| 1 HP:0002725 \| Systemic lupus erythematosus \| 1 HP:0000855 \| Insulin resistance \| 1 HP:0002621 \| Atherosclerosis \| 1 HP:0002268 \| Paroxysmal dystonia \| 1 HP:0011703 \| Sinus tach \| 1 HP:0010550 \| Paraplegia \| 1 HP:0002153 \| Elevated serum potassium levels \| 1 HP:0001258 \| Spastic paraplegia, lower limb \| 1 HP:0002271 \| Autonomic dysregulation \| 1 HP:0000718 \| Aggressive behaviour \| 1 HP:0001298 \| Encephalopathy \| 1 HP:0001907 \| Thromboembolic disease \| 1 HP:0010527 \| Somatosensory agnosia \| 1 HP:0100654 \| Retrobulbar optic neuritis \| 1 HP:0001138 \| Damaged optic nerve \| 1 HP:0001888 \| Lymphocytopenia \| 1 HP:0100021 \| Cerebral palsy \| 1 HP:0000488 \| Noninflammatory retina disease \| 1 HP:0001289 \| Confusion \| 1 HP:0010302 \| Tumor of the spinal cord \| 1 HP:0100502 \| Vitamin B12 deficiency \| 1 HP:0001324 \| Muscular weakness \| 1 HP:0004326 \| Cachexia \| 1 HP:0001276 \| Hypertonia \| 1 HP:0001394 \| Hepatic cirrhosis \| 1 HP:0002613 \| Biliary cirrhosis \| 1 HP:0002721 \| Immunodeficiency \| 1 HP:0001281 \| Tetany \| 1 HP:0001645 \| Sudden cardiac death \| 1 HP:0007185 \| Loss of consciousness \| 1 HP:0010992 \| Stress urinary incontinence \| 1 HP:0001050 \| Plethora \| 1 HP:0010536 \| Central sleep apnoea \| 1 HP:0011505 \| Cystoid macular edema \| 1 HP:0001880 \| Eosinophilia \| 1 HP:0001287 \| Meningitis \| 1 HP:0002313 \| Spastic paraparesis \| 1

Disease ID	280
Disease	multiple sclerosis
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:161) C0015672 \| fatigue \| 130 C0026838 \| spasticity \| 60 C0011570 \| depression \| 55 C0030193 \| pain \| 40 C0029134 \| optic neuritis \| 37 C0027813 \| neuritis \| 36 C0042485 \| venous insufficiency \| 32 C0023524 \| progressive multifocal leukoencephalopathy \| 21 C0679466 \| cognitive deficits \| 16 C0423716 \| neuropathic pain \| 14 C0040997 \| trigeminal neuralgia \| 14 C0009450 \| infection \| 13 C0033953 \| sexual dysfunction \| 12 C0003467 \| anxiety \| 12 C0042164 \| uveitis \| 12 C0040822 \| tremor \| 10 C0235946 \| brain atrophy \| 10 C0271388 \| pendular nystagmus \| 9 C0086132 \| depressive symptoms \| 9 C0851578 \| sleep disorders \| 8 C0028738 \| nystagmus \| 8 C0011168 \| dysphagia \| 8 C0021311 \| infections \| 8 C0221505 \| brain lesions \| 7 C0042166 \| intermediate uveitis \| 6 C0018681 \| headache \| 6 C0497327 \| dementia \| 6 C0574785 \| lower urinary tract symptoms \| 6 C0235946 \| cortical atrophy \| 6 C0851578 \| sleep disorder \| 6 C1839611 \| n syndrome \| 6 C0014544 \| epilepsy \| 5 C0848771 \| neurological disability \| 5 C1282963 \| acquired pendular nystagmus \| 5 C0004364 \| autoimmune disease \| 5 C0422833 \| ent symptoms \| 5 C0021167 \| incontinence \| 5 C0035258 \| restless legs syndrome \| 5 C0149931 \| migraine \| 5 C0041696 \| major depression \| 4 C0878773 \| overactive bladder \| 4 C0005697 \| neurogenic bladder \| 4 C0042384 \| vasculitis \| 4 C0036572 \| seizures \| 4 C0741548 \| bladder symptoms \| 4 C0426359 \| urinary symptoms \| 4 C0150055 \| chronic pain \| 4 C0037763 \| spasms \| 3 C0009241 \| cognitive disorders \| 3 C0030805 \| bullous pemphigoid \| 3 C0233401 \| psychiatric symptoms \| 3 C0037317 \| sleep disturbances \| 3 C0234376 \| cerebellar tremor \| 3 C0231303 \| distress \| 3 C0029456 \| osteoporosis \| 3 C0242422 \| parkinsonism \| 3 C0242350 \| erectile dysfunction \| 3 C0033975 \| psychosis \| 3 C0004134 \| ataxia \| 3 C0026650 \| movement disorders \| 3 C0241910 \| autoimmune hepatitis \| 3 C0031129 \| periphlebitis \| 2 C0442874 \| neuropathy \| 2 C0042029 \| urinary tract infection \| 2 C0006111 \| brain disease \| 2 C0871381 \| social cognition \| 2 C0234243 \| central pain \| 2 C0004364 \| autoimmune diseases \| 2 C0684219 \| myokymia \| 2 C0422943 \| visual symptoms \| 2 C0877040 \| fear of falling \| 2 C0576702 \| lhermitte's sign \| 2 C0267071 \| oropharyngeal dysphagia \| 2 C0027051 \| myocardial infarct \| 2 C0007760 \| cerebellar dysfunction \| 2 C0011053 \| deafness \| 2 C0014544 \| epileptic seizures \| 2 C0003469 \| anxiety disorders \| 2 C0042024 \| urinary incontinence \| 2 C0042769 \| virus infection \| 2 C0028768 \| obsessive-compulsive disorder \| 2 C0221163 \| motor disorders \| 2 C0235169 \| excitability \| 2 C0024299 \| lymphoma \| 2 C0037317 \| sleep disturbance \| 2 C0235946 \| cerebral atrophy \| 2 C0426980 \| motor symptoms \| 2 C0796095 \| c syndrome \| 2 C0008312 \| primary biliary cirrhosis \| 1 C0018801 \| cardiac failure \| 1 C0017636 \| glioblastoma \| 1 C0009324 \| ulcerative colitis \| 1 C0848782 \| urological impairment \| 1 C2315430 \| orthostatic tremor \| 1 C0042847 \| vitamin b12 deficiency \| 1 C0037771 \| spastic paraparesis \| 1 C0748903 \| spinal cord involvement \| 1 C0023487 \| acute promyelocytic leukemia \| 1 C1112443 \| male sexual dysfunction \| 1 C0270871 \| facial myokymia \| 1 C1610071 \| uhthoff's phenomenon \| 1 C0175696 \| g syndrome \| 1 C0017638 \| gliomas \| 1 C0277787 \| stigma \| 1 C0035309 \| retinopathy \| 1 C0575090 \| balance disorders \| 1 C0042769 \| viral infections \| 1 C0037274 \| skin disorders \| 1 C0013421 \| dystonia \| 1 C0015732 \| fecal incontinence \| 1 C0234131 \| motor dysfunction \| 1 C0004936 \| mental disorders \| 1 C0085632 \| apathy \| 1 C0037763 \| muscle spasms \| 1 C0149678 \| epstein-barr virus infection \| 1 C0004659 \| bacteriuria \| 1 C0029132 \| optic neuropathy \| 1 C1299624 \| postural orthostatic tachycardia syndrome \| 1 C0152134 \| internuclear ophthalmoplegia \| 1 C0034150 \| purpura \| 1 C1863307 \| f syndrome \| 1 C0018681 \| headaches \| 1 C1695782 \| cerebral hypoperfusion \| 1 C0086132 \| symptoms of depression \| 1 C0030593 \| pars planitis \| 1 C0037763 \| spasm \| 1 C0021079 \| immunosuppression \| 1 C0011206 \| delirium \| 1 C2004461 \| bowel dysfunction \| 1 C0039494 \| temporomandibular disorders \| 1 C0338474 \| central nervous system demyelination \| 1 C0038220 \| status epilepticus \| 1 C0032285 \| pneumoniae \| 1 C0392171 \| flu-like symptoms \| 1 C0004093 \| weakness \| 1 C1384666 \| hearing loss \| 1 C0013363 \| dysautonomia \| 1 C0393588 \| paroxysmal dystonia \| 1 C0014038 \| brain inflammation \| 1 C0040128 \| thyroid disease \| 1 C0030486 \| paraplegia \| 1 C0011303 \| demyelinating diseases \| 1 C0085582 \| retrobulbar neuritis \| 1 C0028734 \| nocturia \| 1 C0150041 \| hopelessness \| 1 C0155550 \| neural hearing loss \| 1 C0278134 \| sensory loss \| 1 C0026838 \| muscle spasticity \| 1 C0026846 \| muscular atrophy \| 1 C0861152 \| bilateral optic neuritis \| 1 C0037772 \| spastic paraplegia \| 1 C0009951 \| convulsions \| 1 C0024312 \| lymphopenia \| 1 C0178468 \| autoimmune thyroid disease \| 1 C0040822 \| tremors \| 1 C0027726 \| nephrotic syndrome \| 1 C0015967 \| fever \| 1 C0037930 \| spinal cord tumor \| 1 C0235031 \| neurological symptoms \| 1 C0002766 \| analgesia \| 1 C0037928 \| myelopathy \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:510)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs10045431	22194214	3593	IL12B	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.010282454	2012	NA	5	159387525	A	C
rs10045431	22194214	5797	PTPRM	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	NA	5	159387525	A	C
rs10045431	22194214	326625	MMAB	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.001085767	2012	NA	5	159387525	A	C
rs10045431	22194214	162282	ANKFN1	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	NA	5	159387525	A	C
rs10045431	22194214	56144	PCDHA4	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	NA	5	159387525	A	C
rs10045431	22194214	5586	PKN2	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	NA	5	159387525	A	C
rs10201872	21833088	11262	SP140	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122367032	2011	SP140	2	230242009	C	T
rs10201872	21833088	11262	SP140	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122367032	2011	SP140	2	230242009	C	T
rs10243024	19010793	4233	MET	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	MET	7	116706549	G	A
rs10259085	19010793	56913	C1GALT1	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	C1GALT1	7	7228800	C	T
rs10283372	19010793	27067	STAU2	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	STAU2;STAU2-AS1	8	73423256	T	C
rs10283372	19010793	157506	RDH10	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	STAU2;STAU2-AS1	8	73423256	T	C
rs10411936	22190364	58513	EPS15L1	umls:C0026769	GWASCAT	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	0.122367032	2011	EPS15L1	19	16437564	A	G
rs10411936	22190364	58513	EPS15L1	umls:C0026769	GAD	[We have performed a meta-analysis of GWAS in MS that more than doubles the size of previous gene discovery efforts and highlights 3 novel MS susceptibility loci. These and additional loci with suggestive evidence of association are excellent candidates fo]	0.122367032	2011	EPS15L1	19	16437564	A	G
rs10466829	21833088	160365	CLECL1	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122367032	2011	CLECL1	12	9723495	G	A
rs10466829	21833088	160365	CLECL1	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122367032	2011	CLECL1	12	9723495	G	A
rs104895080	20876156	7132	TNFRSF1A	umls:C0026769	BeFree	Concurrent TNFRSF1A R92Q and pyrin E230K mutations in a child with multiple sclerosis.	0.258816704	2010	MEFV	16	3254380	C	T,G
rs104895080	20876156	4210	MEFV	umls:C0026769	BeFree	Concurrent TNFRSF1A R92Q and pyrin E230K mutations in a child with multiple sclerosis.	0.006362715	2010	MEFV	16	3254380	C	T,G
rs10492972	21680216	23095	KIF1B	umls:C0026769	BeFree	Polymorphic locus rs10492972 of the KIF1B gene association with multiple sclerosis in Russia: case control study.	0.243452799	2011	KIF1B	1	10293054	T	C
rs10492972	18997785	23095	KIF1B	umls:C0026769	GAD	[Genetic variation in the KIF1B locus influences susceptibility to multiple sclerosis.]	0.243452799	2008	KIF1B	1	10293054	T	C
rs10492972	21594895	23095	KIF1B	umls:C0026769	BeFree	When is the absence of evidence, evidence of absence? Use of equivalence-based analyses in genetic epidemiology and a conclusion for the KIF1B rs10492972*C allelic association in multiple sclerosis.	0.243452799	2011	KIF1B	1	10293054	T	C
rs10492972	18997785	23095	KIF1B	umls:C0026769	GWASCAT	Genetic variation in the KIF1B locus influences susceptibility to multiple sclerosis.	0.243452799	2008	KIF1B	1	10293054	T	C
rs1049353	22194214	326625	MMAB	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.001085767	2012	CNR1	6	88143916	C	T
rs1049353	22194214	162282	ANKFN1	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	CNR1	6	88143916	C	T
rs1049353	22194214	5586	PKN2	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	CNR1	6	88143916	C	T
rs1049353	22194214	5797	PTPRM	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	CNR1	6	88143916	C	T
rs1049353	22194214	3593	IL12B	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.010282454	2012	CNR1	6	88143916	C	T
rs1049353	22194214	56144	PCDHA4	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	CNR1	6	88143916	C	T
rs1062158	21833088	80762	NDFIP1	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.002367032	2011	NDFIP1	5	142143435	C	T
rs1077667	21833088	8740	TNFSF14	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.242638474	2011	TNFSF14	19	6668961	C	T
rs1077667	21833088	8740	TNFSF14	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.242638474	2011	TNFSF14	19	6668961	C	T
rs10866713	22190364	3593	IL12B	umls:C0026769	GAD	[We have performed a meta-analysis of GWAS in MS that more than doubles the size of previous gene discovery efforts and highlights 3 novel MS susceptibility loci. These and additional loci with suggestive evidence of association are excellent candidates fo]	0.010282454	2011	NA	5	159491886	G	A
rs10876994	25542806	1591	CYP24A1	umls:C0026769	BeFree	Recently, variants of vitamin D metabolizing genes, including rs12368653, rs10876994, rs118204009 and rs703842 in CYP27B1, and rs2248359 in CYP24A1 have been identified to be associated with the pathogenicity of MS in Caucasian populations.	0.125276948	2014	NA	12	57670954	A	C
rs10936599	21833088	55892	MYNN	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122367032	2011	MYNN	3	169774313	C	T
rs10936599	21833088	55892	MYNN	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122367032	2011	MYNN	3	169774313	C	T
rs10984447	17660530	1620	BRINP1	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.007101096	2007	BRINP1	9	119222275	A	G
rs1109670	19010793	8853	ASAP2	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	LOC102723909;LOC105373414;LOC105373416	2	9109909	C	A
rs11129295	21833088	8320	EOMES	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.005005506	2011	NA	3	27747289	C	T
rs11154801	21833088	54806	AHI1	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122367032	2011	AHI1	6	135418217	C	A
rs11154801	21833088	54806	AHI1	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122367032	2011	AHI1	6	135418217	C	A
rs1132200	22194214	162282	ANKFN1	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	TMEM39A	3	119431989	C	T
rs1132200	22194214	5586	PKN2	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	TMEM39A	3	119431989	C	T
rs1132200	22194214	5797	PTPRM	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	TMEM39A	3	119431989	C	T
rs1132200	22194214	56144	PCDHA4	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	TMEM39A	3	119431989	C	T
rs1132200	22194214	326625	MMAB	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.001085767	2012	TMEM39A	3	119431989	C	T
rs1132200	22194214	3593	IL12B	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.010282454	2012	TMEM39A	3	119431989	C	T
rs1138272	25231845	2950	GSTP1	umls:C0026769	BeFree	The results present the first evidence on significantly higher frequency of GSTP1 C341T polymorphism (C-T transition) in healthy subjects compared to MS patients, suggesting it may act as a moderating factor in developing MS clinical phenotype.	0.000542884	2015	GSTP1	11	67586108	C	T
rs113994049	17439913	8893	EIF2B5	umls:C0026769	BeFree	A patient with trauma-associated onset, and clinical features compatible with multiple sclerosis (MS), was homozygous for G338A mutation of eukaryotic translation initiation factor (eIF2B5).	0.002909916	2007	EIF2B5	3	184137637	G	A
rs11581062	21833088	148867	SLC30A7	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122367032	2011	SLC30A7	1	100941963	A	G
rs11581062	21833088	148867	SLC30A7	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122367032	2011	SLC30A7	1	100941963	A	G
rs11594656	19265545	3559	IL2RA	umls:C0026769	BeFree	Using a cohort of over 700 AAV patients, two SLE case-control studies and an SLE trio collection (totalling over 1000 SLE patients), and a TaqMan genotyping approach, we tested 3 SNPs in the IL2RA locus, rs11594656, rs2104286 & rs41295061, each with a prior association with autoimmune disease; rs11594656 and rs41295061 with type 1 diabetes (T1D) and rs2104286 with multiple sclerosis (MS) and T1D.	0.303190008	2009	NA	10	6080046	T	A
rs11665646	19010793	5366	PMAIP1	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	NA	18	59925107	C	T
rs11666377	19010793	27151	CPAMD8	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002638474	2009	CPAMD8	19	17007623	C	T
rs11810217	21833088	7813	EVI5	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.1401079	2011	EVI5	1	92682820	C	T
rs118204009	25542806	1591	CYP24A1	umls:C0026769	BeFree	Recently, variants of vitamin D metabolizing genes, including rs12368653, rs10876994, rs118204009 and rs703842 in CYP27B1, and rs2248359 in CYP24A1 have been identified to be associated with the pathogenicity of MS in Caucasian populations.	0.125276948	2014	CYP27B1	12	57764147	C	T
rs11865121	19525953	23274	CLEC16A	umls:C0026769	GWASCAT	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	0.282115893	2009	CLEC16A	16	11072831	C	A
rs11957313	19010793	30820	KCNIP1	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	KCNIP1	5	170523390	G	A
rs11962089	21654844	64208	POPDC3	umls:C0026769	GAD	[the genetic architecture of disease severity is likely polygenic and comprised of modest effects, similar to what has been described for MS susceptibility, to date.]	0.002367032	2011	POPDC3;BVES-AS1	6	105164345	A	G
rs12025416	21244703	84852	ATP1A1-AS1	umls:C0026769	GAD	[The results are consistent with the polygenic model of inheritance. The cumulative genetic risk established using currently available genome-wide association data provides important insights into disease heterogeneity and completeness of current knowledge]	0.002367032	2011	LOC105378922;LOC105378923	1	116495665	T	C
rs12047808	19010793	126859	AXDND1	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	AXDND1	1	179500179	A	G
rs12048904	21833088	7412	VCAM1	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.125005506	2011	NA	1	100865980	T	C
rs12115114	22194214	162282	ANKFN1	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	NA	8	63477322	A	G
rs12115114	22194214	3593	IL12B	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.010282454	2012	NA	8	63477322	A	G
rs12115114	22194214	5586	PKN2	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	NA	8	63477322	A	G
rs12115114	22194214	56144	PCDHA4	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	NA	8	63477322	A	G
rs12115114	22194214	5797	PTPRM	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	NA	8	63477322	A	G
rs12115114	22194214	326625	MMAB	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.001085767	2012	NA	8	63477322	A	G
rs12212193	21833088	60468	BACH2	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122638474	2011	BACH2	6	90287050	A	G
rs12212193	21833088	60468	BACH2	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122638474	2011	BACH2	6	90287050	A	G
rs12368653	21833088	116986	AGAP2	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.12	2011	AGAP2	12	57739473	G	A
rs12368653	25542806	1591	CYP24A1	umls:C0026769	BeFree	Recently, variants of vitamin D metabolizing genes, including rs12368653, rs10876994, rs118204009 and rs703842 in CYP27B1, and rs2248359 in CYP24A1 have been identified to be associated with the pathogenicity of MS in Caucasian populations.	0.125276948	2014	AGAP2	12	57739473	G	A
rs12466022	21833088	23498	HAAO	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.004734064	2011	LOC100506047;LOC105374570	2	43131922	C	A,T
rs1250540	19525953	57178	ZMIZ1	umls:C0026769	GAD	[Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.]	0.127101096	2009	ZMIZ1	10	79276250	A	G
rs1250542	22190364	57178	ZMIZ1	umls:C0026769	GAD	[We have performed a meta-analysis of GWAS in MS that more than doubles the size of previous gene discovery efforts and highlights 3 novel MS susceptibility loci. These and additional loci with suggestive evidence of association are excellent candidates fo]	0.127101096	2011	ZMIZ1	10	79274913	G	A
rs1250542	22190364	57178	ZMIZ1	umls:C0026769	GWASCAT	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	0.127101096	2011	ZMIZ1	10	79274913	G	A
rs1250550	21833088	57178	ZMIZ1	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.127101096	2011	ZMIZ1	10	79300560	C	A
rs12638253	19010793	389170	LEKR1	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	LEKR1	3	156908302	C	T
rs12644284	21654844	23321	TRIM2	umls:C0026769	GAD	[the genetic architecture of disease severity is likely polygenic and comprised of modest effects, similar to what has been described for MS susceptibility, to date.]	0.002367032	2011	TRIM2;LOC105377496	4	153232848	A	G
rs12649437	19010793	54798	DCHS2	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	DCHS2	4	154466019	A	G
rs12708716	18987646	10666	CD226	umls:C0026769	BeFree	Two of these seven SNPs showed evidence of association with multiple sclerosis; that is rs12708716 from the CLEC16A gene (P=1.6 x 10(-16)) and rs763361 from the CD226 gene (P=5.4 x 10(-8)).	0.018826635	2009	CLEC16A	16	11086016	A	G
rs12708716	18987646	23274	CLEC16A	umls:C0026769	BeFree	Two of these seven SNPs showed evidence of association with multiple sclerosis; that is rs12708716 from the CLEC16A gene (P=1.6 x 10(-16)) and rs763361 from the CD226 gene (P=5.4 x 10(-8)).	0.282115893	2009	CLEC16A	16	11086016	A	G
rs12722489	22190364	3559	IL2RA	umls:C0026769	GAD	[We have performed a meta-analysis of GWAS in MS that more than doubles the size of previous gene discovery efforts and highlights 3 novel MS susceptibility loci. These and additional loci with suggestive evidence of association are excellent candidates fo]	0.303190008	2011	IL2RA	10	6060049	C	T
rs12722489	22190364	3559	IL2RA	umls:C0026769	GWASCAT	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	0.303190008	2011	IL2RA	10	6060049	C	T
rs12722489	17660530	3559	IL2RA	umls:C0026769	GWASCAT	Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.	0.303190008	2007	IL2RA	10	6060049	C	T
rs12722489	21239413	3559	IL2RA	umls:C0026769	BeFree	Genome-wide association studies have identified an association between two intronic single nucleotide polymorphisms (SNPs), rs12722489 and rs2104286, in the interleukin-2 receptor alpha-chain gene (IL2RA) and susceptibility to multiple sclerosis (MS).	0.303190008	2011	IL2RA	10	6060049	C	T
rs13102150	25129256	8821	INPP4B	umls:C0026769	BeFree	An association of an INPP4B polymorphism (rs13102150) with MS was observed in German and Spanish MS cohorts (3676 controls and 911 cases) (P = 8.8 × 10(-3)).	0.000542884	2014	INPP4B	4	142548980	C	A
rs13117816	20802204	401124	DTHD1	umls:C0026769	GAD	[from these analyses indicated that variance in the activity of neurochemical pathways implicated in neurodegeneration is explained, at least in part, by the inheritance of common genetic polymorphisms.]	0.002367032	2010	NA	4	37062709	G	T
rs13277113	21765104	10666	CD226	umls:C0026769	BeFree	We replicated the genetic association with rs13277113 (p = 0.0009, OR 1.46) and rs2736340 (p = 0.0001, OR 1.63) from C8orf13-BLK (8p23.1, associated with RA and systemic lupus erythematosus), and rs763361 (p = 0.03) from CD226 (18q22.3, associated with multiple sclerosis and type 1 diabetes) in the Colombian population.	0.018826635	2011	NA	8	11491677	G	A
rs13277113	21765104	640	BLK	umls:C0026769	BeFree	We replicated the genetic association with rs13277113 (p = 0.0009, OR 1.46) and rs2736340 (p = 0.0001, OR 1.63) from C8orf13-BLK (8p23.1, associated with RA and systemic lupus erythematosus), and rs763361 (p = 0.03) from CD226 (18q22.3, associated with multiple sclerosis and type 1 diabetes) in the Colombian population.	0.000271442	2011	NA	8	11491677	G	A
rs13277113	21765104	83648	FAM167A	umls:C0026769	BeFree	We replicated the genetic association with rs13277113 (p = 0.0009, OR 1.46) and rs2736340 (p = 0.0001, OR 1.63) from C8orf13-BLK (8p23.1, associated with RA and systemic lupus erythematosus), and rs763361 (p = 0.03) from CD226 (18q22.3, associated with multiple sclerosis and type 1 diabetes) in the Colombian population.	0.000271442	2011	NA	8	11491677	G	A
rs13279485	23412934	100131395	LOC100131395	umls:C0026769	GWASCAT	A genome-wide association study of brain lesion distribution in multiple sclerosis.	0.12	2013	ARHGEF10;LOC100131395	8	1935186	T	C
rs13279485	23412934	9639	ARHGEF10	umls:C0026769	GWASCAT	A genome-wide association study of brain lesion distribution in multiple sclerosis.	0.12	2013	ARHGEF10;LOC100131395	8	1935186	T	C
rs1335532	21833088	965	CD58	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.272942951	2011	CD58	1	116558335	A	G
rs1335532	19525955	965	CD58	umls:C0026769	GWASCAT	We also replicated several known MS associations (HLA-DR15, P = 7.0 x 10(-184); CD58, P = 9.6 x 10(-8); EVI5-RPL5, P = 2.5 x 10(-6); IL2RA, P = 7.4 x 10(-6); CLEC16A, P = 1.1 x 10(-4); IL7R, P = 1.3 x 10(-3); TYK2, P = 3.5 x 10(-3)) and observed a statistical interaction between SNPs in EVI5-RPL5 and HLA-DR15 (P = 0.001).	0.272942951	2009	CD58	1	116558335	A	G
rs1386330	19010793	65084	TMEM135	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	NA	11	88086259	T	C
rs140522	21833088	440836	ODF3B	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122367032	2011	ODF3B	22	50532837	T	C
rs140522	21833088	440836	ODF3B	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122367032	2011	ODF3B	22	50532837	T	C
rs1437898	19010793	344148	NCKAP5	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	NCKAP5	2	132989057	A	C
rs1458175	19010793	29951	PDZRN4	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	PDZRN4	12	41572059	A	C
rs151719	17660530	3109	HLA-DMB	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.005005506	2007	HLA-DMB;LOC105379644	6	32936123	C	T
rs1517440	22194214	3593	IL12B	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.010282454	2012	LOC105373895	2	220589153	T	C
rs1517440	22194214	162282	ANKFN1	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	LOC105373895	2	220589153	T	C
rs1517440	22194214	326625	MMAB	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.001085767	2012	LOC105373895	2	220589153	T	C
rs1517440	22194214	5586	PKN2	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	LOC105373895	2	220589153	T	C
rs1517440	22194214	56144	PCDHA4	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	LOC105373895	2	220589153	T	C
rs1517440	22194214	5797	PTPRM	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	LOC105373895	2	220589153	T	C
rs1529316	19010793	64478	CSMD1	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	CSMD1	8	3970616	C	T
rs1557351	19010793	23335	WDR7	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	NA	18	57085083	T	C
rs16914086	19010793	55357	TBC1D2	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	TBC1D2	9	98226195	G	A
rs16944	21621860	3557	IL1RN	umls:C0026769	BeFree	Single nucleotide polymorphisms in human pro- and anti-inflammatory genes, including IL1RN VNTR (rs315952), IL1A 4845G>T (rs17561), L1B-511C>T (rs16944), IL6-174G>C (rs1800795), IL10-1082 A>G (rs 1800896) and TNFα-308G>A (rs1800629) and their impact on multiple sclerosis risk and disease progression in a Polish population were investigated.	0.026470615	2011	IL1B	2	112837290	A	G
rs16944	21621860	3552	IL1A	umls:C0026769	BeFree	Single nucleotide polymorphisms in human pro- and anti-inflammatory genes, including IL1RN VNTR (rs315952), IL1A 4845G>T (rs17561), L1B-511C>T (rs16944), IL6-174G>C (rs1800795), IL10-1082 A>G (rs 1800896) and TNFα-308G>A (rs1800629) and their impact on multiple sclerosis risk and disease progression in a Polish population were investigated.	0.012996872	2011	IL1B	2	112837290	A	G
rs17000900	17126411	3456	IFNB1	umls:C0026769	BeFree	The objective of this study was to evaluate the associations between two MXA promoter region single nucleotide polymorphisms (rs2071430 and rs17000900) and the gene expression responses, clinical and MRI phenotypes in IFN-beta treated MS patients.	0.164711964	2007	MX1	21	41426103	C	A
rs17066096	21833088	53832	IL20RA	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.002367032	2011	NA	6	137131771	A	G
rs170934	22190364	8320	EOMES	umls:C0026769	GAD	[We have performed a meta-analysis of GWAS in MS that more than doubles the size of previous gene discovery efforts and highlights 3 novel MS susceptibility loci. These and additional loci with suggestive evidence of association are excellent candidates fo]	0.005005506	2011	NA	3	28037594	C	T
rs17149161	21654844	7532	YWHAG	umls:C0026769	GAD	[the genetic architecture of disease severity is likely polygenic and comprised of modest effects, similar to what has been described for MS susceptibility, to date.]	0.002367032	2011	YWHAG	7	76348912	C	A
rs17157903	19010793	5649	RELN	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	RELN	7	103987589	C	T
rs17174870	21833088	10461	MERTK	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122909916	2011	MERTK	2	111907624	C	T
rs17174870	21833088	10461	MERTK	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122909916	2011	MERTK	2	111907624	C	T
rs1738074	22190364	117289	TAGAP	umls:C0026769	GWASCAT	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	0.124734064	2011	TAGAP;LOC105378082	6	159044945	T	C
rs1738074	21833088	117289	TAGAP	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.124734064	2011	TAGAP;LOC105378082	6	159044945	T	C
rs1738074	21833088	117289	TAGAP	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.124734064	2011	TAGAP;LOC105378082	6	159044945	T	C
rs1738074	22190364	117289	TAGAP	umls:C0026769	GAD	[We have performed a meta-analysis of GWAS in MS that more than doubles the size of previous gene discovery efforts and highlights 3 novel MS susceptibility loci. These and additional loci with suggestive evidence of association are excellent candidates fo]	0.124734064	2011	TAGAP;LOC105378082	6	159044945	T	C
rs17411949	23472185	64084	CLSTN2	umls:C0026769	GWASCAT	Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles.	0.12	2013	CLSTN2	3	140380851	C	T
rs17445836	19525953	3394	IRF8	umls:C0026769	GAD	[Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.]	0.133463811	2009	NA	16	85984057	G	A
rs1755289	19010793	6456	SH3GL2	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	ADAMTSL1	9	17938353	T	C,G
rs17561	21621860	3552	IL1A	umls:C0026769	BeFree	Single nucleotide polymorphisms in human pro- and anti-inflammatory genes, including IL1RN VNTR (rs315952), IL1A 4845G>T (rs17561), L1B-511C>T (rs16944), IL6-174G>C (rs1800795), IL10-1082 A>G (rs 1800896) and TNFα-308G>A (rs1800629) and their impact on multiple sclerosis risk and disease progression in a Polish population were investigated.	0.012996872	2011	IL1A	2	112779646	C	A
rs17561	21621860	3557	IL1RN	umls:C0026769	BeFree	Single nucleotide polymorphisms in human pro- and anti-inflammatory genes, including IL1RN VNTR (rs315952), IL1A 4845G>T (rs17561), L1B-511C>T (rs16944), IL6-174G>C (rs1800795), IL10-1082 A>G (rs 1800896) and TNFα-308G>A (rs1800629) and their impact on multiple sclerosis risk and disease progression in a Polish population were investigated.	0.026470615	2011	IL1A	2	112779646	C	A
rs17758761	22194214	5586	PKN2	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	ANKFN1	17	55977164	A	C
rs17758761	22194214	56144	PCDHA4	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	ANKFN1	17	55977164	A	C
rs17758761	22194214	3593	IL12B	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.010282454	2012	ANKFN1	17	55977164	A	C
rs17758761	22194214	5797	PTPRM	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	ANKFN1	17	55977164	A	C
rs17758761	22194214	326625	MMAB	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.001085767	2012	ANKFN1	17	55977164	A	C
rs17758761	22194214	162282	ANKFN1	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	ANKFN1	17	55977164	A	C
rs17824933	19525953	923	CD6	umls:C0026769	GWASCAT	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	0.252106602	2009	CD6	11	60993140	C	A,G
rs17824933	21849685	923	CD6	umls:C0026769	BeFree	Our recent meta-analysis of genome-wide association studies of multiple sclerosis (MS) identified a new susceptibility locus tagged by a single nucleotide polymorphism, rs17824933 (p = 3.8 × 10(-9)), that is found in a block of linkage disequilibrium containing the CD6 gene.	0.252106602	2011	CD6	11	60993140	C	A,G
rs17824933	19525953	923	CD6	umls:C0026769	GAD	[Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.]	0.252106602	2009	CD6	11	60993140	C	A,G
rs1790100	19525953	10198	MPHOSPH9	umls:C0026769	GWASCAT	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	0.129468128	2009	MPHOSPH9	12	123172178	G	T
rs1790100	19525953	10198	MPHOSPH9	umls:C0026769	GAD	[Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.]	0.129468128	2009	MPHOSPH9	12	123172178	G	T
rs1799864	20637631	6347	CCL2	umls:C0026769	BeFree	Lack of association between monocyte protein-1 (MCP-1) -2518 A>G chemoattractant and C-C chemokine receptor 2 (CCR2) Val64Ile polymorphisms and multiple sclerosis in a Tunisian population.	0.013625632	2010	CCR2	3	46357717	G	A
rs1799864	25604634	729230	CCR2	umls:C0026769	BeFree	The +190 G/A (rs1799864) polymorphism in the C-C chemokine receptor 2 (CCR2) gene is associated with susceptibility to multiple sclerosis in HLA-DRB1*15:01-negative individuals.	0.001357209	2015	CCR2	3	46357717	G	A
rs1799864	20637631	729230	CCR2	umls:C0026769	BeFree	Lack of association between monocyte protein-1 (MCP-1) -2518 A>G chemoattractant and C-C chemokine receptor 2 (CCR2) Val64Ile polymorphisms and multiple sclerosis in a Tunisian population.	0.001357209	2010	CCR2	3	46357717	G	A
rs1799864	25604634	3123	HLA-DRB1	umls:C0026769	BeFree	The +190 G/A (rs1799864) polymorphism in the C-C chemokine receptor 2 (CCR2) gene is associated with susceptibility to multiple sclerosis in HLA-DRB1*15:01-negative individuals.	0.296822005	2015	CCR2	3	46357717	G	A
rs1800206	18977277	5465	PPARA	umls:C0026769	BeFree	We investigated the association of two common single nucleotide polymorphisms in the PPARA (Leu162Val) and the PPARG (Pro12Ala) genes in 116 patients with clinically definite multiple sclerosis (MS) and 211 age-matched healthy controls.	0.002909916	2009	PPARA	22	46218377	C	G
rs1800562	15014978	3077	HFE	umls:C0026769	BeFree	Extended haplotype analysis in the HLA complex reveals an increased frequency of the HFE-C282Y mutation in individuals with multiple sclerosis.	0.008544182	2004	HFE	6	26092913	G	A
rs1800629	21621860	3552	IL1A	umls:C0026769	BeFree	Single nucleotide polymorphisms in human pro- and anti-inflammatory genes, including IL1RN VNTR (rs315952), IL1A 4845G>T (rs17561), L1B-511C>T (rs16944), IL6-174G>C (rs1800795), IL10-1082 A>G (rs 1800896) and TNFα-308G>A (rs1800629) and their impact on multiple sclerosis risk and disease progression in a Polish population were investigated.	0.012996872	2011	TNF	6	31575254	G	A
rs1800629	21621860	3557	IL1RN	umls:C0026769	BeFree	Single nucleotide polymorphisms in human pro- and anti-inflammatory genes, including IL1RN VNTR (rs315952), IL1A 4845G>T (rs17561), L1B-511C>T (rs16944), IL6-174G>C (rs1800795), IL10-1082 A>G (rs 1800896) and TNFα-308G>A (rs1800629) and their impact on multiple sclerosis risk and disease progression in a Polish population were investigated.	0.026470615	2011	TNF	6	31575254	G	A
rs1800693	23624563	7124	TNF	umls:C0026769	BeFree	To investigate the roles of 2 polymorphisms of the tumor necrosis factor (TNF) receptor superfamily member 1A (TNFRSF1A) gene, rs1800693 (a common variant) and rs4149584 (a coding polymorphism that results in an amino acid substitution-R92Q), as genetic modifiers of multiple sclerosis (MS), and to evaluate their potential functional implications in the disease.	0.085226457	2013	TNFRSF1A	12	6330843	T	C
rs1800693	23624563	7132	TNFRSF1A	umls:C0026769	BeFree	TNFRSF1A polymorphisms rs1800693 and rs4149584 in patients with multiple sclerosis.	0.258816704	2013	TNFRSF1A	12	6330843	T	C
rs1800693	21833088	7132	TNFRSF1A	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.258816704	2011	TNFRSF1A	12	6330843	T	C
rs1800693	19525953	7132	TNFRSF1A	umls:C0026769	GAD	[Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.]	0.258816704	2009	TNFRSF1A	12	6330843	T	C
rs1800693	24790215	7132	TNFRSF1A	umls:C0026769	BeFree	The TNF-α inverse association with relapse was only present among persons carrying the wild-type of the functional SNP rs1800693 in TNFRSF1A that has been previously associated with MS risk.	0.258816704	2015	TNFRSF1A	12	6330843	T	C
rs1800693	19525953	7132	TNFRSF1A	umls:C0026769	GWASCAT	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	0.258816704	2009	TNFRSF1A	12	6330843	T	C
rs1800795	21621860	3557	IL1RN	umls:C0026769	BeFree	Single nucleotide polymorphisms in human pro- and anti-inflammatory genes, including IL1RN VNTR (rs315952), IL1A 4845G>T (rs17561), L1B-511C>T (rs16944), IL6-174G>C (rs1800795), IL10-1082 A>G (rs 1800896) and TNFα-308G>A (rs1800629) and their impact on multiple sclerosis risk and disease progression in a Polish population were investigated.	0.026470615	2011	IL6;LOC541472	7	22727026	C	G
rs1800795	21621860	3552	IL1A	umls:C0026769	BeFree	Single nucleotide polymorphisms in human pro- and anti-inflammatory genes, including IL1RN VNTR (rs315952), IL1A 4845G>T (rs17561), L1B-511C>T (rs16944), IL6-174G>C (rs1800795), IL10-1082 A>G (rs 1800896) and TNFα-308G>A (rs1800629) and their impact on multiple sclerosis risk and disease progression in a Polish population were investigated.	0.012996872	2011	IL6;LOC541472	7	22727026	C	G
rs1801131	19854238	4524	MTHFR	umls:C0026769	BeFree	The variant methylenetetrahydrofolate reductase c.1298A>C (p.E429A) is associated with multiple sclerosis in a German case-control study.	0.010825337	2010	MTHFR	1	11794419	T	G
rs1801157	19927352	6387	CXCL12	umls:C0026769	GAD	[CXCL12 rs1801157 polymorphism in patients with breast cancer, Hodgkin's lymphoma, and non-Hodgkin's lymphoma.]	0.012735362	2009	CXCL12	10	44372809	C	T
rs1801282	18977277	5468	PPARG	umls:C0026769	BeFree	Association of the PPARgamma gene polymorphism Pro12Ala with delayed onset of multiple sclerosis.	0.003452799	2009	PPARG	3	12351626	C	G
rs1801282	18977277	5465	PPARA	umls:C0026769	BeFree	We investigated the association of two common single nucleotide polymorphisms in the PPARA (Leu162Val) and the PPARG (Pro12Ala) genes in 116 patients with clinically definite multiple sclerosis (MS) and 211 age-matched healthy controls.	0.002909916	2009	PPARG	3	12351626	C	G
rs180515	21833088	6198	RPS6KB1	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122638474	2011	RPS6KB1	17	59946914	A	G
rs180515	23739915	643	CXCR5	umls:C0026769	BeFree	We tested five single nucleotide polymorphisms rs228614 (MANBA), rs630923 (CXCR5), rs2744148 (SOX8), rs180515 (RPS6KB1), and rs6062314 (ZBTB46) for association with multiple sclerosis risk in a total of 8499 cases with multiple sclerosis, 8765 unrelated control subjects and 958 trios of European descent.	0.122909916	2013	RPS6KB1	17	59946914	A	G
rs180515	21833088	6198	RPS6KB1	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122638474	2011	RPS6KB1	17	59946914	A	G
rs1805192	18977277	5465	PPARA	umls:C0026769	BeFree	We investigated the association of two common single nucleotide polymorphisms in the PPARA (Leu162Val) and the PPARG (Pro12Ala) genes in 116 patients with clinically definite multiple sclerosis (MS) and 211 age-matched healthy controls.	0.002909916	2009	PPARG	3	12379739	C	G
rs1805192	18977277	5468	PPARG	umls:C0026769	BeFree	Association of the PPARgamma gene polymorphism Pro12Ala with delayed onset of multiple sclerosis.	0.003452799	2009	PPARG	3	12379739	C	G
rs182455	19012073	3925	STMN1	umls:C0026769	GAD	[Analysis of the stathmin rs182455 single nucleotide promoter polymorphism in patients with multiple sclerosis.]	0.005362824	2008	STMN1;LOC105376885	1	25908492	A	G
rs182455	19012073	3925	STMN1	umls:C0026769	BeFree	Analysis of the stathmin rs182455 single nucleotide promoter polymorphism in patients with multiple sclerosis.	0.005362824	2008	STMN1;LOC105376885	1	25908492	A	G
rs1841770	19010793	7545	ZIC1	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	NA	3	148038899	G	T
rs1927457	19010793	6840	SVIL	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	SVIL	10	29719734	T	C
rs199476059	25992516	129831	RBM45	umls:C0026769	BeFree	The objective of this study was to investigate the association between the HLA alleles at the DQA1, DQB1 and DRB1 loci, the CIITA genetic polymorphisms -168A/G and +1614G/C, and susceptibility to multiple sclerosis (MS) in a sample from Rio de Janeiro State, Brazil.	0.016286512	2014	CIITA;LOC105371080	16	10877163	G	A
rs2039485	19010793	80224	NUBPL	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	NA	14	31884044	T	C
rs2049306	19010793	64478	CSMD1	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	CSMD1	8	3974558	T	G
rs2069762	19523143	3558	IL2	umls:C0026769	BeFree	We undertook this study to investigate the potential role of polymorphisms rs3136534, rs6822844 and rs2069762 (-330 T/G IL2) in multiple sclerosis (MS) (805 patients of Spanish Caucasian origin and 952 health controls).	0.029542352	2009	IL2	4	122456825	A	C
rs2069763	18650128	3558	IL2	umls:C0026769	BeFree	An IL-2 genetic G/T polymorphism (rs2069763) has been linked with multiple sclerosis and rheumatoid arthritis.	0.029542352	2008	IL2	4	122456327	C	A
rs2071430	17126411	3456	IFNB1	umls:C0026769	BeFree	The objective of this study was to evaluate the associations between two MXA promoter region single nucleotide polymorphisms (rs2071430 and rs17000900) and the gene expression responses, clinical and MRI phenotypes in IFN-beta treated MS patients.	0.164711964	2007	MX1	21	41426138	G	T
rs2072633	17660530	7936	NELFE	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002367032	2007	CFB;NELFE	6	31951801	A	G
rs2072633	17660530	629	CFB	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.004734064	2007	CFB;NELFE	6	31951801	A	G
rs2073723	17660530	6941	TCF19	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002367032	2007	TCF19	6	31162301	T	C
rs2076530	17660530	56244	BTNL2	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.13246392	2007	BTNL2;LOC101929163	6	32396039	T	C
rs2076533	17660530	56244	BTNL2	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.13246392	2007	BTNL2;LOC101929163	6	32395750	C	T
rs2104286	19265545	3559	IL2RA	umls:C0026769	BeFree	Using a cohort of over 700 AAV patients, two SLE case-control studies and an SLE trio collection (totalling over 1000 SLE patients), and a TaqMan genotyping approach, we tested 3 SNPs in the IL2RA locus, rs11594656, rs2104286 & rs41295061, each with a prior association with autoimmune disease; rs11594656 and rs41295061 with type 1 diabetes (T1D) and rs2104286 with multiple sclerosis (MS) and T1D.	0.303190008	2009	IL2RA	10	6057082	T	C
rs2104286	19525953	3559	IL2RA	umls:C0026769	GWASCAT	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	0.303190008	2009	IL2RA	10	6057082	T	C
rs2104286	21911588	3559	IL2RA	umls:C0026769	BeFree	IL2RA gene polymorphism rs2104286 A>G seen in multiple sclerosis is associated with intermediate uveitis: possible parallel pathways?	0.303190008	2011	IL2RA	10	6057082	T	C
rs2104286	21239413	3559	IL2RA	umls:C0026769	BeFree	Genome-wide association studies have identified an association between two intronic single nucleotide polymorphisms (SNPs), rs12722489 and rs2104286, in the interleukin-2 receptor alpha-chain gene (IL2RA) and susceptibility to multiple sclerosis (MS).	0.303190008	2011	IL2RA	10	6057082	T	C
rs2116078	19010793	8989	TRPA1	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	NA	8	72451754	T	G
rs2119704	21833088	101928791	LOC101928791	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.12	2011	LOC101928791	14	88021345	C	A
rs2119704	21833088	8477	GPR65	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.002367032	2011	LOC101928791	14	88021345	C	A
rs2150702	22190364	2315	MLANA	umls:C0026769	GAD	[We have performed a meta-analysis of GWAS in MS that more than doubles the size of previous gene discovery efforts and highlights 3 novel MS susceptibility loci. These and additional loci with suggestive evidence of association are excellent candidates fo]	0.122367032	2011	MLANA;KIAA2026	9	5893861	G	T,A
rs2150702	22190364	2315	MLANA	umls:C0026769	GWASCAT	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	0.122367032	2011	MLANA;KIAA2026	9	5893861	G	T,A
rs2228570	22805623	7421	VDR	umls:C0026769	BeFree	The aim of this study is to measure plasma levels of OPG and RANKL as well as to analyze VDR FokI polymorphism (rs2228570) in MS patients and healthy individuals to detect any potential correlation.	0.029923414	2012	VDR	12	47879112	A	T,G,C
rs2248359	21833088	1591	CYP24A1	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.125276948	2011	CYP24A1	20	54174979	C	T
rs2248359	25542806	1591	CYP24A1	umls:C0026769	BeFree	Recently, variants of vitamin D metabolizing genes, including rs12368653, rs10876994, rs118204009 and rs703842 in CYP27B1, and rs2248359 in CYP24A1 have been identified to be associated with the pathogenicity of MS in Caucasian populations.	0.125276948	2014	CYP24A1	20	54174979	C	T
rs2248359	21833088	1591	CYP24A1	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.125276948	2011	CYP24A1	20	54174979	C	T
rs2277680	24854635	58191	CXCL16	umls:C0026769	BeFree	The gender-specific association of CXCL16 A181V gene polymorphism with susceptibility to multiple sclerosis, and its effects on PBMC mRNA and plasma soluble CXCL16 levels: preliminary findings.	0.000542884	2014	CXCL16	17	4735268	G	A
rs2283792	21833088	5594	MAPK1	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.123452799	2011	MAPK1	22	21776836	T	G
rs2283792	21833088	5594	MAPK1	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.123452799	2011	MAPK1	22	21776836	T	G
rs228614	21833088	4126	MANBA	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122367032	2011	MANBA	4	102657480	G	A
rs228614	23739915	643	CXCR5	umls:C0026769	BeFree	We tested five single nucleotide polymorphisms rs228614 (MANBA), rs630923 (CXCR5), rs2744148 (SOX8), rs180515 (RPS6KB1), and rs6062314 (ZBTB46) for association with multiple sclerosis risk in a total of 8499 cases with multiple sclerosis, 8765 unrelated control subjects and 958 trios of European descent.	0.122909916	2013	MANBA	4	102657480	G	A
rs228614	21833088	4126	MANBA	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122367032	2011	MANBA	4	102657480	G	A
rs2293152	22190364	6774	STAT3	umls:C0026769	GWASCAT	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	0.127915422	2011	STAT3	17	42329511	G	T,C,A
rs2293152	22190364	6774	STAT3	umls:C0026769	GAD	[We have performed a meta-analysis of GWAS in MS that more than doubles the size of previous gene discovery efforts and highlights 3 novel MS susceptibility loci. These and additional loci with suggestive evidence of association are excellent candidates fo]	0.127915422	2011	STAT3	17	42329511	G	T,C,A
rs2293370	21833088	51300	TIMMDC1	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.12	2011	TIMMDC1	3	119501087	G	A
rs2300603	21833088	10538	BATF	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122367032	2011	BATF	14	75539214	T	C
rs2300603	21833088	10538	BATF	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122367032	2011	BATF	14	75539214	T	C
rs2300747	22190364	100616384	MIR548AC	umls:C0026769	GWASCAT	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	0.120271442	2011	CD58;MIR548AC	1	116561593	A	G
rs2300747	22190364	965	CD58	umls:C0026769	GAD	[We have performed a meta-analysis of GWAS in MS that more than doubles the size of previous gene discovery efforts and highlights 3 novel MS susceptibility loci. These and additional loci with suggestive evidence of association are excellent candidates fo]	0.272942951	2011	CD58;MIR548AC	1	116561593	A	G
rs2300747	19525953	100616384	MIR548AC	umls:C0026769	GWASCAT	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	0.120271442	2009	CD58;MIR548AC	1	116561593	A	G
rs2300747	22190364	965	CD58	umls:C0026769	GWASCAT	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	0.272942951	2011	CD58;MIR548AC	1	116561593	A	G
rs2300747	19525953	965	CD58	umls:C0026769	GWASCAT	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	0.272942951	2009	CD58;MIR548AC	1	116561593	A	G
rs2303759	21833088	27120	DKKL1	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122367032	2011	DKKL1	19	49365794	T	G
rs2303759	21833088	27120	DKKL1	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122367032	2011	DKKL1	19	49365794	T	G
rs2304256	19966805	7297	TYK2	umls:C0026769	BeFree	The highest association was at marker rs2304256 (odds ratio (OR) = 0.86; 95%CI = 0.82-0.90) in the TYK2 gene, which has previously been associated with systemic lupus erythematosus and multiple sclerosis.	0.133192369	2010	TYK2	19	10364976	C	A
rs233100	21833088	8915	BCL10	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.002638474	2011	NA	1	85306326	G	A
rs241427	17660530	6891	TAP2	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.008458305	2007	TAP2	6	32836637	A	G
rs2425752	21833088	57727	NCOA5	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.12	2011	NCOA5	20	46073481	T	C
rs2476601	16391555	26191	PTPN22	umls:C0026769	GAD	[Evaluating the role of the 620W allele of protein tyrosine phosphatase PTPN22 in Crohn's disease and multiple sclerosis.]	0.005819831	2006	PTPN22;AP4B1-AS1	1	113834946	A	G
rs2503875	20598377	221002	RASGEF1A	umls:C0026769	GAD	[Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis.]	0.002367032	2010	LOC105378271	10	43318601	G	A
rs2523393	19525953	285830	HLA-F-AS1	umls:C0026769	GWASCAT	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	0.12	2009	HLA-F;HLA-F-AS1	6	29737882	A	G
rs2523393	19525953	3134	HLA-F	umls:C0026769	GWASCAT	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	0.124734064	2009	HLA-F;HLA-F-AS1	6	29737882	A	G
rs2546890	22190364	285626	LOC285626	umls:C0026769	GWASCAT	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	0.12	2011	LOC285626	5	159332892	A	G
rs2546890	22190364	3593	IL12B	umls:C0026769	GAD	[We have performed a meta-analysis of GWAS in MS that more than doubles the size of previous gene discovery efforts and highlights 3 novel MS susceptibility loci. These and additional loci with suggestive evidence of association are excellent candidates fo]	0.010282454	2011	LOC285626	5	159332892	A	G
rs2546890	21833088	285626	LOC285626	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.12	2011	LOC285626	5	159332892	A	G
rs2546890	21833088	3593	IL12B	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.010282454	2011	LOC285626	5	159332892	A	G
rs261902	19010793	636	BICD1	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	BICD1	12	32323793	A	G
rs261949	19010793	414777	HCG18	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	HCG18;HCG17	6	30302303	G	A
rs2681424	22190364	286676	ILDR1	umls:C0026769	GAD	[We have performed a meta-analysis of GWAS in MS that more than doubles the size of previous gene discovery efforts and highlights 3 novel MS susceptibility loci. These and additional loci with suggestive evidence of association are excellent candidates fo]	0.002367032	2011	ILDR1	3	122050675	T	C
rs2736177	17660530	199	AIF1	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002367032	2007	NA	6	31618317	C	T
rs2736340	21765104	83648	FAM167A	umls:C0026769	BeFree	We replicated the genetic association with rs13277113 (p = 0.0009, OR 1.46) and rs2736340 (p = 0.0001, OR 1.63) from C8orf13-BLK (8p23.1, associated with RA and systemic lupus erythematosus), and rs763361 (p = 0.03) from CD226 (18q22.3, associated with multiple sclerosis and type 1 diabetes) in the Colombian population.	0.000271442	2011	NA	8	11486464	C	T
rs2736340	21765104	10666	CD226	umls:C0026769	BeFree	We replicated the genetic association with rs13277113 (p = 0.0009, OR 1.46) and rs2736340 (p = 0.0001, OR 1.63) from C8orf13-BLK (8p23.1, associated with RA and systemic lupus erythematosus), and rs763361 (p = 0.03) from CD226 (18q22.3, associated with multiple sclerosis and type 1 diabetes) in the Colombian population.	0.018826635	2011	NA	8	11486464	C	T
rs2736340	21765104	640	BLK	umls:C0026769	BeFree	We replicated the genetic association with rs13277113 (p = 0.0009, OR 1.46) and rs2736340 (p = 0.0001, OR 1.63) from C8orf13-BLK (8p23.1, associated with RA and systemic lupus erythematosus), and rs763361 (p = 0.03) from CD226 (18q22.3, associated with multiple sclerosis and type 1 diabetes) in the Colombian population.	0.000271442	2011	NA	8	11486464	C	T
rs2736428	19010793	80736	SLC44A4	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.004734064	2009	SLC44A4	6	31876147	C	T
rs2744148	23739915	643	CXCR5	umls:C0026769	BeFree	We tested five single nucleotide polymorphisms rs228614 (MANBA), rs630923 (CXCR5), rs2744148 (SOX8), rs180515 (RPS6KB1), and rs6062314 (ZBTB46) for association with multiple sclerosis risk in a total of 8499 cases with multiple sclerosis, 8765 unrelated control subjects and 958 trios of European descent.	0.122909916	2013	NA	16	1023552	A	G
rs2744148	21833088	30812	SOX8	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.002638474	2011	NA	16	1023552	A	G
rs28359178	19387457	7351	UCP2	umls:C0026769	BeFree	We reported earlier that two mitochondrial gene polymorphisms, UCP2 -866 G/A (rs659366) and mtDNA nt13708 G/A (rs28359178), are associated with multiple sclerosis (MS).	0.013635564	2009	ND5	MT	13708	G	A
rs2842483	19010793	26578	OSTF1	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	PCSK5	9	76291234	A	G
rs2842483	19010793	5125	PCSK5	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	PCSK5	9	76291234	A	G
rs2844779	19010793	7726	TRIM26	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.004734064	2009	HCG17	6	30237630	G	T
rs2844780	19010793	7726	TRIM26	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.004734064	2009	HCG17	6	30236749	G	T
rs2844786	19010793	89870	TRIM15	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.004734064	2009	NA	6	30176643	C	A
rs2894249	17660530	10665	C6orf10	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.127101096	2007	C6orf10;LOC101929163	6	32358058	C	T
rs2903692	19337309	23274	CLEC16A	umls:C0026769	BeFree	Independent genome-wide association studies highlighted the function of CLEC16A/KIAA0350 polymorphisms modifying the risk to either multiple sclerosis (rs6498169) or type 1 diabetes (rs2903692).	0.282115893	2009	CLEC16A	16	11144926	G	A
rs2905747	17660530	352961	HCG26	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002367032	2007	LOC102725068	6	31483699	A	G
rs290986	21833088	6850	SYK	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122367032	2011	SYK	9	90801254	A	G
rs290986	21833088	6850	SYK	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122367032	2011	SYK	9	90801254	A	G
rs299175	19010793	204801	NLRP11	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	NLRP11	19	55802162	G	A
rs305217	22194214	326625	MMAB	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.001085767	2012	PKN2	1	88754789	G	A
rs305217	22194214	5797	PTPRM	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	PKN2	1	88754789	G	A
rs305217	22194214	3593	IL12B	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.010282454	2012	PKN2	1	88754789	G	A
rs305217	22194214	5586	PKN2	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	PKN2	1	88754789	G	A
rs305217	22194214	56144	PCDHA4	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	PKN2	1	88754789	G	A
rs305217	22194214	162282	ANKFN1	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	PKN2	1	88754789	G	A
rs307896	21833088	10055	SAE1	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122367032	2011	SAE1	19	47158236	G	A
rs307896	21833088	10055	SAE1	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122367032	2011	SAE1	19	47158236	G	A
rs3087456	16426246	4261	CIITA	umls:C0026769	BeFree	We analysed whether the single nucleotide polymorphism (SNP) rs3087456 in the promoter of the MHC class II transactivator (MHC2TA) gene is associated with manifestation of rheumatoid arthritis, multiple sclerosis, narcolepsy and Wegener granulomatosis.	0.135635346	2006	CIITA;LOC105371080	16	10877045	G	A
rs3094127	19010793	10211	FLOT1	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	FLOT1	6	30729670	A	G
rs3095238	17660530	100130889	PSORS1C3	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002367032	2007	NA	6	31193433	T	G
rs3115537	17660530	7919	DDX39B	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002367032	2007	DDX39B;MCCD1;ATP6V1G2-DDX39B	6	31530058	G	C
rs3115537	17660530	401250	MCCD1	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002367032	2007	DDX39B;MCCD1;ATP6V1G2-DDX39B	6	31530058	G	C
rs3115576	17660530	4855	NOTCH4	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002909916	2007	NA	6	32249073	T	A
rs3118470	21833088	3559	IL2RA	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.303190008	2011	IL2RA	10	6059750	T	A,C
rs3129871	23472185	3122	HLA-DRA	umls:C0026769	GWASCAT	Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles.	0.2601079	2013	HLA-DRA	6	32438565	A	C
rs3129889	22190364	3122	HLA-DRA	umls:C0026769	GAD	[We have performed a meta-analysis of GWAS in MS that more than doubles the size of previous gene discovery efforts and highlights 3 novel MS susceptibility loci. These and additional loci with suggestive evidence of association are excellent candidates fo]	0.2601079	2011	NA	6	32445768	G	A
rs3129900	17660530	10665	C6orf10	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.127101096	2007	C6orf10;LOC101929163	6	32338202	G	T
rs3129932	17660530	10665	C6orf10	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.127101096	2007	C6orf10;LOC101929163	6	32368350	G	C
rs3129934	22457343	10665	C6orf10	umls:C0026769	GWASCAT	A genome-wide association study in progressive multiple sclerosis.	0.127101096	2012	C6orf10;LOC101929163	6	32368410	T	C
rs3129934	17660530	10665	C6orf10	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.127101096	2007	C6orf10;LOC101929163	6	32368410	T	C
rs3129934	18941528	10665	C6orf10	umls:C0026769	GAD	[Identification of a novel risk locus for multiple sclerosis at 13q31.3 by a pooled genome-wide scan of 500,000 single nucleotide polymorphisms.]	0.127101096	2008	C6orf10;LOC101929163	6	32368410	T	C
rs3129934	18941528	10665	C6orf10	umls:C0026769	GWASCAT	Identification of a novel risk locus for multiple sclerosis at 13q31.3 by a pooled genome-wide scan of 500,000 single nucleotide polymorphisms.	0.127101096	2008	C6orf10;LOC101929163	6	32368410	T	C
rs3129934	22457343	10665	C6orf10	umls:C0026769	GAD	[We have confirmed the established association with the HLA region and, despite the low statistical power of the study, we found suggestive evidence for association with a novel locus on chromosome 7, with a putative regulatory role.]	0.127101096	2012	C6orf10;LOC101929163	6	32368410	T	C
rs3130000	17660530	8449	DHX16	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002367032	2007	DHX16	6	30660305	A	G
rs3130311	17660530	4855	NOTCH4	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002909916	2007	NA	6	32249590	A	G
rs3130501	17660530	5460	POU5F1	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002367032	2007	POU5F1	6	31168676	A	G
rs3130532	17660530	253018	HCG27	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002367032	2007	NA	6	31240676	A	G
rs3130558	17660530	170679	PSORS1C1	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002367032	2007	PSORS1C1	6	31129406	C	G
rs3130952	17660530	253018	HCG27	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002367032	2007	NA	6	31210138	G	A
rs3130981	17660530	170679	PSORS1C1	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002367032	2007	CDSN;PSORS1C1	6	31116036	T	C
rs3130981	17660530	1041	CDSN	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002638474	2007	CDSN;PSORS1C1	6	31116036	T	C
rs3131009	17660530	170679	PSORS1C1	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002367032	2007	PSORS1C1	6	31131055	G	A
rs3131294	17660530	4855	NOTCH4	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002909916	2007	NOTCH4	6	32212369	A	G
rs3132524	17660530	5460	POU5F1	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002367032	2007	POU5F1	6	31168937	T	C
rs3134926	17660530	4855	NOTCH4	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002909916	2007	NA	6	32232370	C	G
rs3135338	20159113	56244	BTNL2	umls:C0026769	GAD	[Genome-wide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 gene.]	0.13246392	2010	NA	6	32433440	C	T
rs3135377	17660530	56244	BTNL2	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.13246392	2007	NA	6	32417622	A	G
rs3135388	17660530	3122	HLA-DRA	umls:C0026769	GAD	[Of these SNPs, two within the interleukin-2 receptor alpha gene (IL2RA) were strongly associated with multiple sclerosis (P=2.96x10(-8)), as were a nonsynonymous SNP in the interleukin-7 receptor alpha gene (IL7RA) (P=2.94x10(-7)) and multiple SNPs in the HLA-DRA locus (P=8.94x10(-81)).]	0.2601079	2007	HLA-DRA	6	32445274	A	G
rs3135388	19433080	3123	HLA-DRB1	umls:C0026769	BeFree	The tag SNP for HLA-DRB1*1501, rs3135388, is significantly associated with multiple sclerosis susceptibility: cost-effective high-throughput detection by real-time PCR.	0.296822005	2009	HLA-DRA	6	32445274	A	G
rs3135388	24733291	3127	HLA-DRB5	umls:C0026769	BeFree	We demonstrate the methods by replicating a PheWAS on rs3135388 (near HLA-DRB, associated with multiple sclerosis) and performing a novel PheWAS using an individual's maximum white blood cell count (WBC) as a continuous measure.	0.023169705	2015	HLA-DRA	6	32445274	A	G
rs3135388	19525953	3122	HLA-DRA	umls:C0026769	GAD	[Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.]	0.2601079	2009	HLA-DRA	6	32445274	A	G
rs3135388	17660530	3122	HLA-DRA	umls:C0026769	GWASCAT	Of these SNPs, two within the interleukin-2 receptor alpha gene (IL2RA) were strongly associated with multiple sclerosis (P=2.96x10(-8)), as were a nonsynonymous SNP in the interleukin-7 receptor alpha gene (IL7RA) (P=2.94x10(-7)) and multiple SNPs in the HLA-DRA locus (P=8.94x10(-81)).	0.2601079	2007	HLA-DRA	6	32445274	A	G
rs3135388	23186557	3123	HLA-DRB1	umls:C0026769	BeFree	Association of HLA-DRB1*1501 tagging rs3135388 gene polymorphism with multiple sclerosis.	0.296822005	2013	HLA-DRA	6	32445274	A	G
rs3135388	19525953	3122	HLA-DRA	umls:C0026769	GWASCAT	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	0.2601079	2009	HLA-DRA	6	32445274	A	G
rs3135388	25958306	3123	HLA-DRB1	umls:C0026769	BeFree	The same study cohorts were also genotyped for the rs3135388 polymorphism tagging the HLA-DRB1*15:01 allele, which is a known genetic factor associated with susceptibility to develop MS in many populations.	0.296822005	2016	HLA-DRA	6	32445274	A	G
rs3136534	19523143	3558	IL2	umls:C0026769	BeFree	We undertook this study to investigate the potential role of polymorphisms rs3136534, rs6822844 and rs2069762 (-330 T/G IL2) in multiple sclerosis (MS) (805 patients of Spanish Caucasian origin and 952 health controls).	0.029542352	2009	NA	4	122448621	T	G
rs315952	21621860	3552	IL1A	umls:C0026769	BeFree	Single nucleotide polymorphisms in human pro- and anti-inflammatory genes, including IL1RN VNTR (rs315952), IL1A 4845G>T (rs17561), L1B-511C>T (rs16944), IL6-174G>C (rs1800795), IL10-1082 A>G (rs 1800896) and TNFα-308G>A (rs1800629) and their impact on multiple sclerosis risk and disease progression in a Polish population were investigated.	0.012996872	2011	IL1RN	2	113132727	T	A,C
rs315952	21621860	3557	IL1RN	umls:C0026769	BeFree	Single nucleotide polymorphisms in human pro- and anti-inflammatory genes, including IL1RN VNTR (rs315952), IL1A 4845G>T (rs17561), L1B-511C>T (rs16944), IL6-174G>C (rs1800795), IL10-1082 A>G (rs 1800896) and TNFα-308G>A (rs1800629) and their impact on multiple sclerosis risk and disease progression in a Polish population were investigated.	0.026470615	2011	IL1RN	2	113132727	T	A,C
rs354033	21833088	79970	ZNF767P	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122367032	2011	ZNF767P	7	149592373	G	A
rs354033	21833088	79970	ZNF767P	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122367032	2011	ZNF767P	7	149592373	G	A
rs35667974	20116863	64135	IFIH1	umls:C0026769	BeFree	No evidence of association of the rare nsSNP rs35667974 in IFIH1 with multiple sclerosis.	0.010639772	2010	IFIH1	2	162268127	T	C
rs371856018	16844954	4359	MPZ	umls:C0026769	BeFree	Myelin protein zero mutation His39Pro: hereditary motor and sensory neuropathy with variable onset, hearing loss, restless legs and multiple sclerosis.	0.002995792	2006	MPZ	1	161307376	T	C,G
rs3732378	22261545	1524	CX3CR1	umls:C0026769	BeFree	The association of V249I and T280M fractalkine receptor haplotypes with disease course of multiple sclerosis.	0.003538676	2012	CX3CR1	3	39265671	G	A
rs3732379	22261545	1524	CX3CR1	umls:C0026769	BeFree	The association of V249I and T280M fractalkine receptor haplotypes with disease course of multiple sclerosis.	0.003538676	2012	CX3CR1	3	39265765	C	T
rs3743930	22337722	4210	MEFV	umls:C0026769	BeFree	Familial Mediterranean fever-associated mutation pyrin E148Q as a potential risk factor for multiple sclerosis.	0.006362715	2012	MEFV	16	3254626	C	G
rs3745672	20598377	163059	ZNF433	umls:C0026769	GWASCAT	Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis.	0.122638474	2010	ZNF433;LOC101928464	19	12035555	T	C
rs3745672	20598377	163059	ZNF433	umls:C0026769	GAD	[Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis.]	0.122638474	2010	ZNF433;LOC101928464	19	12035555	T	C
rs3745672	20598377	101928464	LOC101928464	umls:C0026769	GWASCAT	Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis.	0.12	2010	ZNF433;LOC101928464	19	12035555	T	C
rs3780792	20598377	7410	VAV2	umls:C0026769	GWASCAT	Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis.	0.122638474	2010	VAV2	9	133970221	A	G
rs3806156	17660530	56244	BTNL2	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.13246392	2007	BTNL2;LOC101929163	6	32405921	G	T
rs3807031	19010793	6992	PPP1R11	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	PPP1R11	6	30066107	C	A
rs3817963	23472185	56244	BTNL2	umls:C0026769	GWASCAT	Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles.	0.13246392	2013	BTNL2;LOC101929163	6	32400310	T	C
rs3823355	19010793	10255	HCG9	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.004734064	2009	HCG9	6	29974306	C	A,T
rs3823375	19010793	10255	HCG9	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.004734064	2009	HCG9	6	29976381	T	C
rs3828840	23472185	3128	HLA-DRB6	umls:C0026769	GWASCAT	Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles.	0.12	2013	HLA-DRB4;HLA-DRB6	6	32553130	T	C
rs386572987	17463067	5444	PON1	umls:C0026769	BeFree	Glyoxalase I A111E, paraoxonase 1 Q192R and L55M polymorphisms: susceptibility factors of multiple sclerosis?	0.008815624	2007	NA	NA	NA	NA	NA
rs386572987	17463067	2739	GLO1	umls:C0026769	BeFree	Glyoxalase I A111E, paraoxonase 1 Q192R and L55M polymorphisms: susceptibility factors of multiple sclerosis?	0.005362824	2007	NA	NA	NA	NA	NA
rs386602118	17656372	627	BDNF	umls:C0026769	BeFree	Preservation of gray matter volume in multiple sclerosis patients with the Met allele of the rs6265 (Val66Met) SNP of brain-derived neurotrophic factor.	0.01953134	2007	NA	NA	NA	NA	NA
rs386602118	23593393	627	BDNF	umls:C0026769	BeFree	Functional magnetic resonance imaging was used to assess how the Brain Derived Neurotrophic Factor Val(66)Met polymorphism modulated brain regional activity and functional connectivity in 26 cognitively unimpaired Multiple Sclerosis patients and 25 age- and education-matched healthy controls while performing an episodic memory task that included encoding and retrieving visual scenes.	0.01953134	2013	NA	NA	NA	NA	NA
rs386602118	16356643	627	BDNF	umls:C0026769	BeFree	No association of the Val66Met polymorphism of brain-derived neurotrophic factor (BDNF) to multiple sclerosis.	0.01953134	2006	NA	NA	NA	NA	NA
rs386602118	20953813	627	BDNF	umls:C0026769	BeFree	To investigate in multiple sclerosis (MS) patients, the relationship between the Val66Met polymorphism of BDNF and clinical markers of disease activity and MRI markers of focal and diffuse brain pathologies.	0.01953134	2011	NA	NA	NA	NA	NA
rs397020	19010793	55321	TMEM74B	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	RAD21L1	20	1225242	T	C
rs397020	19010793	642636	RAD21L1	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.122367032	2009	RAD21L1	20	1225242	T	C
rs397020	19010793	642636	RAD21L1	umls:C0026769	GWASCAT	Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.	0.122367032	2009	RAD21L1	20	1225242	T	C
rs397507444	23523621	4524	MTHFR	umls:C0026769	BeFree	Association of methylenetetrahydrofolate reductase A1298C polymorphism but not of C677T with multiple sclerosis in Tunisian patients.	0.010825337	2013	MTHFR	1	11794407	T	G
rs4075958	21833088	10636	RGS14	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122367032	2011	RGS14	5	177357511	G	A
rs4075958	21833088	10636	RGS14	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122367032	2011	RGS14	5	177357511	G	A
rs41295061	19265545	3559	IL2RA	umls:C0026769	BeFree	Using a cohort of over 700 AAV patients, two SLE case-control studies and an SLE trio collection (totalling over 1000 SLE patients), and a TaqMan genotyping approach, we tested 3 SNPs in the IL2RA locus, rs11594656, rs2104286 & rs41295061, each with a prior association with autoimmune disease; rs11594656 and rs41295061 with type 1 diabetes (T1D) and rs2104286 with multiple sclerosis (MS) and T1D.	0.303190008	2009	NA	10	6072697	C	A
rs4149584	23624563	7132	TNFRSF1A	umls:C0026769	BeFree	TNFRSF1A polymorphisms rs1800693 and rs4149584 in patients with multiple sclerosis.	0.258816704	2013	TNFRSF1A	12	6333477	C	T,G
rs4149584	19525953	7132	TNFRSF1A	umls:C0026769	GAD	[Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.]	0.258816704	2009	TNFRSF1A	12	6333477	C	T,G
rs4149584	23624563	7124	TNF	umls:C0026769	BeFree	To investigate the roles of 2 polymorphisms of the tumor necrosis factor (TNF) receptor superfamily member 1A (TNFRSF1A) gene, rs1800693 (a common variant) and rs4149584 (a coding polymorphism that results in an amino acid substitution-R92Q), as genetic modifiers of multiple sclerosis (MS), and to evaluate their potential functional implications in the disease.	0.085226457	2013	TNFRSF1A	12	6333477	C	T,G
rs4285028	21833088	6565	SLC15A2	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122367032	2011	SLC15A2	3	121941817	A	C
rs4285028	21833088	6565	SLC15A2	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122367032	2011	SLC15A2	3	121941817	A	C
rs4308217	21833088	942	CD86	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.125005506	2011	CD86	3	122074340	C	A,T
rs4409785	21833088	143686	SESN3	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.002367032	2011	NA	11	95578258	T	C
rs4680	24290452	1312	COMT	umls:C0026769	BeFree	Catechol-O-methyltransferase Val158Met polymorphism (rs4680) is associated with pain in multiple sclerosis.	0.002909916	2013	COMT;MIR4761	22	19963748	G	A
rs4680534	19525953	3592	IL12A	umls:C0026769	GAD	[Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.]	0.132649486	2009	IL12A-AS1	3	159981157	T	C
rs4711211	19010793	7726	TRIM26	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.004734064	2009	TRIM26	6	30195032	A	G
rs4746	17463067	5444	PON1	umls:C0026769	BeFree	Glyoxalase I A111E, paraoxonase 1 Q192R and L55M polymorphisms: susceptibility factors of multiple sclerosis?	0.008815624	2007	GLO1	6	38682852	T	G
rs4746	17463067	2739	GLO1	umls:C0026769	BeFree	Glyoxalase I A111E, paraoxonase 1 Q192R and L55M polymorphisms: susceptibility factors of multiple sclerosis?	0.005362824	2007	GLO1	6	38682852	T	G
rs4763655	21610746	3820	KLRB1	umls:C0026769	BeFree	Alterations in KLRB1 gene expression and a Scandinavian multiple sclerosis association study of the KLRB1 SNP rs4763655.	0.005276948	2011	KLRB1	12	9602982	G	A
rs4774	19659749	4261	CIITA	umls:C0026769	BeFree	The objectives of this study were: (i) to reappraise the association that was found in the previous study; (ii) to evaluate if MS patients with minor allele C and HHV-6A active infection had different clinical behavior; and (iii) to analyze the possible association of MHC2TA rs4774C with Epstein-Barr virus (EBV).	0.135635346	2010	CIITA	16	10906991	G	C
rs4774	25992516	3123	HLA-DRB1	umls:C0026769	BeFree	The CIITA genetic polymorphism rs4774C in combination with the HLA-DRB115:01 allele as a putative susceptibility factor to multiple sclerosis in Brazilian females.	0.296822005	2014	CIITA	16	10906991	G	C
rs4774	19659749	4261	CIITA	umls:C0026769	GAD	[MHC2TA rs4774C and HHV-6A active replication in multiple sclerosis patients.]	0.135635346	2010	CIITA	16	10906991	G	C
rs4774	25992516	4261	CIITA	umls:C0026769	BeFree	The CIITA genetic polymorphism rs4774C in combination with the HLA-DRB115:01 allele as a putative susceptibility factor to multiple sclerosis in Brazilian females.	0.135635346	2014	CIITA	16	10906991	G	C
rs4798571	22194214	326625	MMAB	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.001085767	2012	PTPRM	18	7584296	G	A
rs4798571	22194214	162282	ANKFN1	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	PTPRM	18	7584296	G	A
rs4798571	22194214	5797	PTPRM	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	PTPRM	18	7584296	G	A
rs4798571	22194214	56144	PCDHA4	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	PTPRM	18	7584296	G	A
rs4798571	22194214	3593	IL12B	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.010282454	2012	PTPRM	18	7584296	G	A
rs4798571	22194214	5586	PKN2	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	PTPRM	18	7584296	G	A
rs486416	17660530	10919	EHMT2	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002367032	2007	EHMT2	6	31888293	G	A
rs4902647	21833088	677	ZFP36L1	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122367032	2011	ZFP36L1	14	68787474	C	T
rs4902647	21833088	677	ZFP36L1	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122367032	2011	ZFP36L1	14	68787474	C	T
rs4953911	20117844	4249	MGAT5	umls:C0026769	GWASCAT	MGAT5 alters the severity of multiple sclerosis.	0.12554839	2010	MGAT5	2	134311223	T	A
rs4959093	17660530	10665	C6orf10	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.127101096	2007	C6orf10;LOC101929163	6	32345320	T	C
rs4961252	21502966	5747	PTK2	umls:C0026769	GAD	[Single-nucleotide polymorphisms in HLA- and non-HLA genes associated with the development of antibodies to interferon-I2 therapy in multiple sclerosis patients.]	0.002367032	2012	NA	8	141094845	A	G
rs4986790	15932772	7099	TLR4	umls:C0026769	BeFree	Impact of the Asp299Gly polymorphism in the toll-like receptor 4 (tlr-4) gene on disease course of multiple sclerosis.	0.011539974	2005	TLR4	9	117713024	A	G
rs533259	23412934	6041	RNASEL	umls:C0026769	GWASCAT	A genome-wide association study of brain lesion distribution in multiple sclerosis.	0.12	2013	RNASEL	1	182579884	A	G
rs539703	17660530	10665	C6orf10	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.127101096	2007	C6orf10;LOC101929163	6	32320685	A	C
rs544358	17660530	10665	C6orf10	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.127101096	2007	C6orf10;LOC101929163	6	32305381	G	C
rs5498	12590979	3383	ICAM1	umls:C0026769	BeFree	Intercellular adhesion molecule-1 K469E polymorphism: study of association with multiple sclerosis.	0.13507865	2003	ICAM1;ICAM4;LOC105372272	19	10285007	A	G
rs574710	17660530	10665	C6orf10	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.127101096	2007	C6orf10;LOC101929163	6	32320413	T	C
rs6062314	21833088	140685	ZBTB46	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122638474	2011	ZBTB46	20	63778360	C	T
rs6062314	23739915	643	CXCR5	umls:C0026769	BeFree	We tested five single nucleotide polymorphisms rs228614 (MANBA), rs630923 (CXCR5), rs2744148 (SOX8), rs180515 (RPS6KB1), and rs6062314 (ZBTB46) for association with multiple sclerosis risk in a total of 8499 cases with multiple sclerosis, 8765 unrelated control subjects and 958 trios of European descent.	0.122909916	2013	ZBTB46	20	63778360	C	T
rs6062314	21833088	140685	ZBTB46	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122638474	2011	ZBTB46	20	63778360	C	T
rs6074022	19525955	958	CD40	umls:C0026769	GAD	[Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.]	0.131911105	2009	NA	20	46111557	C	T
rs6265	17656372	627	BDNF	umls:C0026769	GAD	[Preservation of gray matter volume in multiple sclerosis patients with the Met allele of the rs6265 (Val66Met) SNP of brain-derived neurotrophic factor.]	0.01953134	2007	BDNF;BDNF-AS	11	27658369	C	T
rs6265	17656372	627	BDNF	umls:C0026769	BeFree	Preservation of gray matter volume in multiple sclerosis patients with the Met allele of the rs6265 (Val66Met) SNP of brain-derived neurotrophic factor.	0.01953134	2007	BDNF;BDNF-AS	11	27658369	C	T
rs630923	21833088	643	CXCR5	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122909916	2011	CXCR5	11	118883644	C	A
rs630923	21833088	643	CXCR5	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122909916	2011	CXCR5	11	118883644	C	A
rs630923	23739915	643	CXCR5	umls:C0026769	BeFree	We tested five single nucleotide polymorphisms rs228614 (MANBA), rs630923 (CXCR5), rs2744148 (SOX8), rs180515 (RPS6KB1), and rs6062314 (ZBTB46) for association with multiple sclerosis risk in a total of 8499 cases with multiple sclerosis, 8765 unrelated control subjects and 958 trios of European descent.	0.122909916	2013	CXCR5	11	118883644	C	A
rs644045	17660530	221527	ZBTB12	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002367032	2007	C2	6	31916180	A	G
rs644045	17660530	717	C2	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002367032	2007	C2	6	31916180	A	G
rs6498169	19337309	23274	CLEC16A	umls:C0026769	BeFree	Independent genome-wide association studies highlighted the function of CLEC16A/KIAA0350 polymorphisms modifying the risk to either multiple sclerosis (rs6498169) or type 1 diabetes (rs2903692).	0.282115893	2009	CLEC16A	16	11155472	G	A
rs6498169	17660530	23274	CLEC16A	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.282115893	2007	CLEC16A	16	11155472	G	A
rs651477	19010793	2019	EN1	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	NA	2	118638115	T	C
rs651477	19010793	51141	INSIG2	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	NA	2	118638115	T	C
rs659366	19387457	7351	UCP2	umls:C0026769	BeFree	We reported earlier that two mitochondrial gene polymorphisms, UCP2 -866 G/A (rs659366) and mtDNA nt13708 G/A (rs28359178), are associated with multiple sclerosis (MS).	0.013635564	2009	UCP2	11	73983709	C	T
rs6604026	19525955	7813	EVI5	umls:C0026769	GAD	[Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.]	0.1401079	2009	RPL5;FAM69A	1	92838046	T	C
rs6604026	19525955	6125	RPL5	umls:C0026769	GAD	[Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.]	0.017383549	2009	RPL5;FAM69A	1	92838046	T	C
rs6604026	17660530	6125	RPL5	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.017383549	2007	RPL5;FAM69A	1	92838046	T	C
rs662	21545792	5444	PON1	umls:C0026769	BeFree	Lack of association between paraoxonase 1 Q192R polymorphism and multiple sclerosis in relapse phase: A case-control study.	0.008815624	2011	PON1	7	95308134	T	C
rs662	17463067	5444	PON1	umls:C0026769	BeFree	Glyoxalase I A111E, paraoxonase 1 Q192R and L55M polymorphisms: susceptibility factors of multiple sclerosis?	0.008815624	2007	PON1	7	95308134	T	C
rs662	19826962	57008	RLFP1	umls:C0026769	BeFree	To investigate the possible association between the PON1 genotype and allelic variants of the polymorphisms L55M and Q192R and the risk for multiple sclerosis in the Spanish Caucasian population; we studied the frequency of the PON1 genotypes and allelic variants in 228 patients with multiple sclerosis and 220 healthy controls using a PCR-RLFP method.	0.000271442	2010	PON1	7	95308134	T	C
rs662	17463067	2739	GLO1	umls:C0026769	BeFree	Glyoxalase I A111E, paraoxonase 1 Q192R and L55M polymorphisms: susceptibility factors of multiple sclerosis?	0.005362824	2007	PON1	7	95308134	T	C
rs6659742	23472185	284677	C1orf204	umls:C0026769	GWASCAT	Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles.	0.12	2013	C1orf204	1	159848723	C	T
rs669607	21833088	8320	EOMES	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.005005506	2011	NA	3	28029953	A	C
rs6718520	22190364	23498	HAAO	umls:C0026769	GAD	[We have performed a meta-analysis of GWAS in MS that more than doubles the size of previous gene discovery efforts and highlights 3 novel MS susceptibility loci. These and additional loci with suggestive evidence of association are excellent candidates fo]	0.004734064	2011	LOC100506047	2	43098432	A	G
rs6718520	22190364	100506047	LOC100506047	umls:C0026769	GWASCAT	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	0.12	2011	LOC100506047	2	43098432	A	G
rs6822844	19523143	3558	IL2	umls:C0026769	BeFree	We undertook this study to investigate the potential role of polymorphisms rs3136534, rs6822844 and rs2069762 (-330 T/G IL2) in multiple sclerosis (MS) (805 patients of Spanish Caucasian origin and 952 health controls).	0.029542352	2009	NA	4	122588266	G	T
rs6887695	22194214	3593	IL12B	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.010282454	2012	NA	5	159395637	G	C
rs6887695	22194214	162282	ANKFN1	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	NA	5	159395637	G	C
rs6887695	22194214	56144	PCDHA4	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	NA	5	159395637	G	C
rs6887695	22194214	326625	MMAB	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.001085767	2012	NA	5	159395637	G	C
rs6887695	22194214	5797	PTPRM	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	NA	5	159395637	G	C
rs6887695	22194214	5586	PKN2	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	NA	5	159395637	G	C
rs6896969	19525953	1601	DAB2	umls:C0026769	GAD	[Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.]	0.002367032	2009	NA	5	40424324	A	C
rs6896969	19525953	5734	PTGER4	umls:C0026769	GAD	[Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.]	0.004734064	2009	NA	5	40424324	A	C
rs6897932	24242875	3574	IL7	umls:C0026769	BeFree	Former studies demonstrated the single nucleotide polymorphism (SNP) rs6897932 C/T in the IL-7 receptor (IL-7R) gene was associated with susceptibility to autoimmune diseases, including multiple sclerosis and type I diabetes.	0.128262808	2014	IL7R	5	35874473	C	T
rs6897932	21161391	3575	IL7R	umls:C0026769	BeFree	Association between the IL7R T244I polymorphism and multiple sclerosis: a meta-analysis.	0.307724693	2011	IL7R	5	35874473	C	T
rs6897932	25421942	3575	IL7R	umls:C0026769	BeFree	The T-allele in the single nucleotide polymorphism rs6897932 in the gene encoding the IL-7 receptor α (IL7RA) is associated with reduced risk of autoimmune diseases including multiple sclerosis and also affects the course of HIV infection.	0.307724693	2014	IL7R	5	35874473	C	T
rs6897932	20194581	3575	IL7R	umls:C0026769	GAD	[Interleukin 7 receptor alpha polymorphism rs6897932 and susceptibility to multiple sclerosis in the Western Balkans.]	0.307724693	2010	IL7R	5	35874473	C	T
rs6897932	18721276	3575	IL7R	umls:C0026769	BeFree	The T244I variant of the interleukin-7 receptor-alpha gene and multiple sclerosis.	0.307724693	2008	IL7R	5	35874473	C	T
rs6897932	21833088	3575	IL7R	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.307724693	2011	IL7R	5	35874473	C	T
rs6897932	19744146	3575	IL7R	umls:C0026769	BeFree	The C allele of a single nucleotide polymorphism (SNP), rs6897932, located in the interleukin-7 receptor alpha chain (IL7RA) was recently found to be associated with multiple sclerosis and Type I diabetes.	0.307724693	2009	IL7R	5	35874473	C	T
rs6897932	17660530	3575	IL7R	umls:C0026769	GWASCAT	Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.	0.307724693	2007	IL7R	5	35874473	C	T
rs6897932	25421942	3574	IL7	umls:C0026769	BeFree	The T-allele in the single nucleotide polymorphism rs6897932 in the gene encoding the IL-7 receptor α (IL7RA) is associated with reduced risk of autoimmune diseases including multiple sclerosis and also affects the course of HIV infection.	0.128262808	2014	IL7R	5	35874473	C	T
rs6897932	20194581	3575	IL7R	umls:C0026769	BeFree	Interleukin 7 receptor alpha polymorphism rs6897932 and susceptibility to multiple sclerosis in the Western Balkans.	0.307724693	2010	IL7R	5	35874473	C	T
rs6904029	19010793	10255	HCG9	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.004734064	2009	HCG9	6	29975290	G	A
rs6911628	19010793	8870	IER3	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	HCG20	6	30772069	C	T
rs6917747	19010793	3482	IGF2R	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	IGF2R	6	159981673	G	A
rs6936204	17660530	4855	NOTCH4	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002909916	2007	NA	6	32249315	T	C
rs6941421	19010793	9308	CD83	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	NA	6	15088920	T	C
rs6971	25833352	706	TSPO	umls:C0026769	BeFree	Four clinically and radiologically stable relapsing-remitting MS subjects (age 41 ± 7 years, two men/two women) and four HCs (age 42 ± 8 years, 2 two men/two women), matched for translocator protein genotype [two high- and two medium-affinity binders according to DNA polymorphism (rs6971) in each group], were studied for TRV.	0.000542884	2015	TSPO	22	43162920	A	G
rs6984045	19525955	50807	ASAP1	umls:C0026769	GAD	[Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.]	0.002367032	2009	ASAP1	8	130080167	T	C
rs703842	19525955	4234	METTL1	umls:C0026769	GAD	[Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.]	0.122638474	2009	CYP27B1;METTL1	12	57768956	A	G
rs703842	19525955	1594	CYP27B1	umls:C0026769	GWASCAT	Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.	0.132258492	2009	CYP27B1;METTL1	12	57768956	A	G
rs703842	25542806	1591	CYP24A1	umls:C0026769	BeFree	Recently, variants of vitamin D metabolizing genes, including rs12368653, rs10876994, rs118204009 and rs703842 in CYP27B1, and rs2248359 in CYP24A1 have been identified to be associated with the pathogenicity of MS in Caucasian populations.	0.125276948	2014	CYP27B1;METTL1	12	57768956	A	G
rs703842	19525955	4234	METTL1	umls:C0026769	GWASCAT	Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.	0.122638474	2009	CYP27B1;METTL1	12	57768956	A	G
rs703842	19525955	1594	CYP27B1	umls:C0026769	GAD	[Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.]	0.132258492	2009	CYP27B1;METTL1	12	57768956	A	G
rs716595	19010793	4601	MXI1	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	MXI1	10	110246728	G	A
rs7191700	22190364	5619	PRM1	umls:C0026769	GAD	[We have performed a meta-analysis of GWAS in MS that more than doubles the size of previous gene discovery efforts and highlights 3 novel MS susceptibility loci. These and additional loci with suggestive evidence of association are excellent candidates fo]	0.002367032	2011	LOC105371082	16	11312946	C	T
rs7191888	19010793	283902	HCCAT5	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	NA	16	73547159	A	G
rs7194	17660530	3122	HLA-DRA	umls:C0026769	GAD	[Of these SNPs, two within the interleukin-2 receptor alpha gene (IL2RA) were strongly associated with multiple sclerosis (P=2.96x10(-8)), as were a nonsynonymous SNP in the interleukin-7 receptor alpha gene (IL7RA) (P=2.94x10(-7)) and multiple SNPs in the HLA-DRA locus (P=8.94x10(-81)).]	0.2601079	2007	HLA-DRA	6	32444703	G	A
rs7200786	21833088	23274	CLEC16A	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.282115893	2011	CLEC16A	16	11083944	A	G
rs7238078	21833088	10892	MALT1	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122367032	2011	MALT1;LOC105372146	18	58716960	T	G
rs7238078	21833088	10892	MALT1	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122367032	2011	MALT1;LOC105372146	18	58716960	T	G
rs7253363	19010793	84337	ELOF1	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	NA	19	11571680	T	G
rs7255066	21833088	5817	PVR	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122367032	2011	PVR	19	44642803	T	C
rs7255066	21833088	5817	PVR	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122367032	2011	PVR	19	44642803	T	C
rs731236	19758194	7421	VDR	umls:C0026769	BeFree	An association of two single-nucleotide polymorphisms (SNPs) of the vitamin D receptor (VDR) gene, Apal (rs7975232) and Taql (rs731236), with multiple sclerosis (MS) has been reported in a Caucasian population.	0.029923414	2009	VDR;LOC105369749	12	47844974	A	G
rs731236	21664963	4155	MBP	umls:C0026769	BeFree	Analyses performed on HLA-DRB1*15-positive MS patients and HC alone confirmed the protective role of rs731236 TT VDR genotype (p(y)=0.004; OR: 0.53; 95% CI: 0.33-0.83); notably, FACS, PCR, and confocal microscopy analyses showed that rs731236 TT genotype is associated with an augmented VDR expression in MBP-stimulated PBMC from patients.	0.061859917	2011	VDR;LOC105369749	12	47844974	A	G
rs733724	23412934	57531	HACE1	umls:C0026769	GWASCAT	A genome-wide association study of brain lesion distribution in multiple sclerosis.	0.12	2013	HACE1	6	104775989	G	A
rs7382297	17660530	3107	HLA-C	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.024841964	2007	NA	6	31279290	T	G
rs744166	20159113	6774	STAT3	umls:C0026769	GAD	[Genome-wide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 gene.]	0.127915422	2010	STAT3	17	42362183	A	G
rs744166	20159113	6774	STAT3	umls:C0026769	GWASCAT	Genome-wide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 gene.	0.127915422	2010	STAT3	17	42362183	A	G
rs7522462	21833088	55765	C1orf106	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.12	2011	C1orf106	1	200912467	G	A
rs7538427	22194214	326625	MMAB	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.001085767	2012	GTF2B	1	88873739	C	T
rs7538427	22194214	162282	ANKFN1	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	GTF2B	1	88873739	C	T
rs7538427	22194214	3593	IL12B	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.010282454	2012	GTF2B	1	88873739	C	T
rs7538427	22194214	5797	PTPRM	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	GTF2B	1	88873739	C	T
rs7538427	22194214	56144	PCDHA4	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	GTF2B	1	88873739	C	T
rs7538427	22194214	5586	PKN2	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	GTF2B	1	88873739	C	T
rs756699	21833088	7416	VDAC1	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.002367032	2011	NA	5	134110884	C	T
rs757259	19010793	135644	TRIM40	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.004734064	2009	TRIM40	6	30147765	G	A
rs757262	19010793	135644	TRIM40	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.004734064	2009	TRIM40	6	30147178	C	T
rs758944	21654844	3315	HSPB1	umls:C0026769	GAD	[the genetic architecture of disease severity is likely polygenic and comprised of modest effects, similar to what has been described for MS susceptibility, to date.]	0.002367032	2011	NA	7	76323980	C	A
rs7592330	22190364	5341	PLEK	umls:C0026769	GAD	[We have performed a meta-analysis of GWAS in MS that more than doubles the size of previous gene discovery efforts and highlights 3 novel MS susceptibility loci. These and additional loci with suggestive evidence of association are excellent candidates fo]	0.004734064	2011	NA	2	68419651	G	A
rs7595037	21833088	5341	PLEK	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.004734064	2011	NA	2	68419963	C	T
rs763361	21765104	640	BLK	umls:C0026769	BeFree	We replicated the genetic association with rs13277113 (p = 0.0009, OR 1.46) and rs2736340 (p = 0.0001, OR 1.63) from C8orf13-BLK (8p23.1, associated with RA and systemic lupus erythematosus), and rs763361 (p = 0.03) from CD226 (18q22.3, associated with multiple sclerosis and type 1 diabetes) in the Colombian population.	0.000271442	2011	CD226	18	69864406	T	A,C
rs763361	21765104	10666	CD226	umls:C0026769	BeFree	We replicated the genetic association with rs13277113 (p = 0.0009, OR 1.46) and rs2736340 (p = 0.0001, OR 1.63) from C8orf13-BLK (8p23.1, associated with RA and systemic lupus erythematosus), and rs763361 (p = 0.03) from CD226 (18q22.3, associated with multiple sclerosis and type 1 diabetes) in the Colombian population.	0.018826635	2011	CD226	18	69864406	T	A,C
rs763361	23073294	10666	CD226	umls:C0026769	BeFree	Recently, there has been increasing evidence shown that a non-synonymous exchange (Gly307Ser/rs763361) of the CD226 gene on chromosome 18q22 is linked to several autoimmune diseases (ADs) including type 1 diabetes (T1D), celiac disease (CED), rheumatoid arthritis (RA), multiple sclerosis (MS), Grave's disease, Wegener's granulomatosis (WG), psoriasis, and primary sicca syndrome (pSS).	0.018826635	2013	CD226	18	69864406	T	A,C
rs763361	18987646	23274	CLEC16A	umls:C0026769	BeFree	Two of these seven SNPs showed evidence of association with multiple sclerosis; that is rs12708716 from the CLEC16A gene (P=1.6 x 10(-16)) and rs763361 from the CD226 gene (P=5.4 x 10(-8)).	0.282115893	2009	CD226	18	69864406	T	A,C
rs763361	22728856	10666	CD226	umls:C0026769	BeFree	There has been more evidence that a non-synonymous exchange (rs763361/Gly307Ser) in the gene for CD226 is linked to several autoimmune diseases including multiple sclerosis (MS).	0.018826635	2012	CD226	18	69864406	T	A,C
rs763361	19536154	10666	CD226	umls:C0026769	BeFree	Novel association of the CD226 (DNAM-1) Gly307Ser polymorphism in Wegener's granulomatosis and confirmation for multiple sclerosis in German patients.	0.018826635	2009	CD226	18	69864406	T	A,C
rs763361	21765104	83648	FAM167A	umls:C0026769	BeFree	We replicated the genetic association with rs13277113 (p = 0.0009, OR 1.46) and rs2736340 (p = 0.0001, OR 1.63) from C8orf13-BLK (8p23.1, associated with RA and systemic lupus erythematosus), and rs763361 (p = 0.03) from CD226 (18q22.3, associated with multiple sclerosis and type 1 diabetes) in the Colombian population.	0.000271442	2011	CD226	18	69864406	T	A,C
rs763361	18987646	10666	CD226	umls:C0026769	BeFree	Two of these seven SNPs showed evidence of association with multiple sclerosis; that is rs12708716 from the CLEC16A gene (P=1.6 x 10(-16)) and rs763361 from the CD226 gene (P=5.4 x 10(-8)).	0.018826635	2009	CD226	18	69864406	T	A,C
rs771767	21833088	64332	NFKBIZ	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.002367032	2011	NA	3	102029794	A	G
rs7756262	17660530	56244	BTNL2	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.13246392	2007	NA	6	32430898	T	A
rs7779014	21654844	7532	YWHAG	umls:C0026769	GAD	[the genetic architecture of disease severity is likely polygenic and comprised of modest effects, similar to what has been described for MS susceptibility, to date.]	0.002367032	2011	YWHAG	7	76346269	C	T
rs7789940	21654844	3315	HSPB1	umls:C0026769	GAD	[the genetic architecture of disease severity is likely polygenic and comprised of modest effects, similar to what has been described for MS susceptibility, to date.]	0.002367032	2011	NA	7	76321913	A	G
rs7923837	21833088	3087	HHEX	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.002367032	2011	NA	10	92722160	G	A
rs7924357	23412934	100128088	LOC100128088	umls:C0026769	GWASCAT	A genome-wide association study of brain lesion distribution in multiple sclerosis.	0.12	2013	NA	11	102757321	G	A
rs794185	20802204	285362	SUMF1	umls:C0026769	GAD	[from these analyses indicated that variance in the activity of neurochemical pathways implicated in neurodegeneration is explained, at least in part, by the inheritance of common genetic polymorphisms.]	0.122367032	2010	SUMF1	3	4395674	T	C
rs794185	20802204	285362	SUMF1	umls:C0026769	GWASCAT	Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis.	0.122367032	2010	SUMF1	3	4395674	T	C
rs7975232	19758194	7421	VDR	umls:C0026769	BeFree	An association of two single-nucleotide polymorphisms (SNPs) of the vitamin D receptor (VDR) gene, Apal (rs7975232) and Taql (rs731236), with multiple sclerosis (MS) has been reported in a Caucasian population.	0.029923414	2009	VDR;LOC105369749	12	47845054	C	A
rs806321	21833088	10301	DLEU1	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.12	2011	DLEU1	13	50267187	C	T
rs806321	21833088	145165	ST13P4	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.004734064	2011	DLEU1	13	50267187	C	T
rs8074980	20802204	404093	CUEDC1	umls:C0026769	GAD	[from these analyses indicated that variance in the activity of neurochemical pathways implicated in neurodegeneration is explained, at least in part, by the inheritance of common genetic polymorphisms.]	0.002367032	2010	CUEDC1	17	57933599	G	A
rs854560	17463067	2739	GLO1	umls:C0026769	BeFree	Glyoxalase I A111E, paraoxonase 1 Q192R and L55M polymorphisms: susceptibility factors of multiple sclerosis?	0.005362824	2007	PON1	7	95316772	A	C,G,N,T
rs854560	19826962	57008	RLFP1	umls:C0026769	BeFree	To investigate the possible association between the PON1 genotype and allelic variants of the polymorphisms L55M and Q192R and the risk for multiple sclerosis in the Spanish Caucasian population; we studied the frequency of the PON1 genotypes and allelic variants in 228 patients with multiple sclerosis and 220 healthy controls using a PCR-RLFP method.	0.000271442	2010	PON1	7	95316772	A	C,G,N,T
rs854560	17463067	5444	PON1	umls:C0026769	BeFree	Glyoxalase I A111E, paraoxonase 1 Q192R and L55M polymorphisms: susceptibility factors of multiple sclerosis?	0.008815624	2007	PON1	7	95316772	A	C,G,N,T
rs8734	25830931	100133941	CD24	umls:C0026769	BeFree	Association between the CD24 Ala57Val polymorphism and risk for multiple sclerosis and systemic lupus erythematosus: a meta-analysis.	0.130530151	2015	NA	NA	NA	NA	NA
rs874628	21833088	84769	MPV17L2	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.122367032	2011	MPV17L2	19	18193890	A	T,G
rs874628	21833088	84769	MPV17L2	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.122367032	2011	MPV17L2	19	18193890	A	T,G
rs882300	19525953	7852	CXCR4	umls:C0026769	GAD	[Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.]	0.005276948	2009	NA	2	136218685	T	C
rs908821	19010793	287015	TRIM42	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	NA	3	140821876	A	G
rs908821	19010793	55186	SLC25A36	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	NA	3	140821876	A	G
rs910049	17660530	10665	C6orf10	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.127101096	2007	C6orf10;LOC101929163	6	32347950	T	C
rs916570	19010793	80352	RNF39	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.004734064	2009	NA	6	30098254	A	G
rs9261535	19010793	10107	TRIM10	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	TRIM10	6	30159546	G	A
rs9263804	17660530	5460	POU5F1	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002367032	2007	POU5F1	6	31167929	C	T
rs926591	17660530	10665	C6orf10	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.127101096	2007	C6orf10;LOC101929163	6	32337913	C	A
rs9267971	17660530	4855	NOTCH4	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.002909916	2007	NA	6	32249408	T	C
rs9268402	17660530	10665	C6orf10	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.127101096	2007	C6orf10;LOC101929163	6	32373576	G	A
rs9268403	17660530	10665	C6orf10	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.127101096	2007	C6orf10;LOC101929163	6	32373696	T	C
rs9268557	17660530	56244	BTNL2	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.13246392	2007	NA	6	32421528	T	C
rs9268560	17660530	56244	BTNL2	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.13246392	2007	NA	6	32421735	C	G
rs9268645	17660530	3122	HLA-DRA	umls:C0026769	GAD	[Of these SNPs, two within the interleukin-2 receptor alpha gene (IL2RA) were strongly associated with multiple sclerosis (P=2.96x10(-8)), as were a nonsynonymous SNP in the interleukin-7 receptor alpha gene (IL7RA) (P=2.94x10(-7)) and multiple SNPs in the HLA-DRA locus (P=8.94x10(-81)).]	0.2601079	2007	HLA-DRA	6	32440750	C	G
rs9282641	21833088	942	CD86	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.125005506	2011	CD86	3	122077921	G	A
rs9282641	21833088	942	CD86	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.125005506	2011	CD86	3	122077921	G	A
rs9283487	23472185	101927027	LOC101927027	umls:C0026769	GWASCAT	Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles.	0.12	2013	PRKRA;LOC101927027	2	178431544	T	C
rs9283487	23472185	8575	PRKRA	umls:C0026769	GWASCAT	Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles.	0.122367032	2013	PRKRA;LOC101927027	2	178431544	T	C
rs929156	19010793	89870	TRIM15	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.004734064	2009	TRIM15	6	30171922	G	A
rs931555	21244703	79925	SPEF2	umls:C0026769	GWASCAT	Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data.	0.122367032	2011	SPEF2	5	35803475	C	T,A
rs931555	21244703	79925	SPEF2	umls:C0026769	GAD	[The results are consistent with the polygenic model of inheritance. The cumulative genetic risk established using currently available genome-wide association data provides important insights into disease heterogeneity and completeness of current knowledge]	0.122367032	2011	SPEF2	5	35803475	C	T,A
rs9320598	23785401	101927314	LOC101927314	umls:C0026769	GWASCAT	Association of genetic markers with CSF oligoclonal bands in multiple sclerosis patients.	0.12	2013	LOC101927314	6	97571204	A	G
rs9321490	21833088	10767	HBS1L	umls:C0026769	GAD	[Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.]	0.002367032	2011	NA	6	135173737	T	C
rs9368716	17660530	10665	C6orf10	umls:C0026769	GAD	[Alleles of IL2RA and IL7RA and those in the HLA locus are identified as heritable risk factors for multiple sclerosis.]	0.127101096	2007	C6orf10;LOC101929163	6	32338313	G	A
rs9480865	19010793	2309	FOXO3	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.002367032	2009	FOXO3	6	108595370	T	C
rs9523762	19010793	2262	GPC5	umls:C0026769	GAD	[Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.]	0.132735362	2009	GPC5;LOC105370315	13	92679633	G	A
rs9523762	19010793	2262	GPC5	umls:C0026769	GWASCAT	Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.	0.132735362	2009	GPC5;LOC105370315	13	92679633	G	A
rs9596270	22190364	145165	ST13P4	umls:C0026769	GAD	[We have performed a meta-analysis of GWAS in MS that more than doubles the size of previous gene discovery efforts and highlights 3 novel MS susceptibility loci. These and additional loci with suggestive evidence of association are excellent candidates fo]	0.004734064	2011	DLEU1	13	50268304	T	C
rs9596270	22190364	10301	DLEU1	umls:C0026769	GWASCAT	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	0.12	2011	DLEU1	13	50268304	T	C
rs9657904	20453840	868	CBLB	umls:C0026769	GWASCAT	Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis.	0.247915422	2010	CBLB	3	105867870	T	C
rs9657904	22194214	5797	PTPRM	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	CBLB	3	105867870	T	C
rs9657904	20453840	868	CBLB	umls:C0026769	GAD	[Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis.]	0.247915422	2010	CBLB	3	105867870	T	C
rs9657904	22194214	3593	IL12B	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.010282454	2012	CBLB	3	105867870	T	C
rs9657904	22194214	326625	MMAB	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.001085767	2012	CBLB	3	105867870	T	C
rs9657904	22194214	56144	PCDHA4	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	CBLB	3	105867870	T	C
rs9657904	22194214	5586	PKN2	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	CBLB	3	105867870	T	C
rs9657904	22194214	162282	ANKFN1	umls:C0026769	BeFree	Replication extended to the following polymorphisms: PKN2 (rs305217), GTF2B (rs7538427), EPHA4 (rs1517440), YTHDF3 (rs12115114), ANKFN1 (rs17758761) and PTPRM (rs4798571), which did not reach the threshold of significance in a follow-up of the first genome-wide association study (GWAS) conducted in multiple sclerosis; TMEM39A (rs1132200), which appeared as a newly identified susceptibility gene in the same study; a gene previously reaching GWAS significance in Italy, CBLB (rs9657904); IL12B (rs6887695, rs10045431), a susceptibility gene shared by diverse autoimmune diseases and, finally, another gene showing inconclusive association with multiple sclerosis, CNR1 (rs1049353).	0.000271442	2012	CBLB	3	105867870	T	C
rs9828519	25914168	4397	MS	umls:C0026769	BeFree	This study identifies and validates the role of rs9828519, an intronic variant in SLC9A9, in IFNβ-treated subjects, demonstrating a successful pharmacogenetic screen in MS. Functional characterization suggests that SLC9A9, an Na(+) -H(+) exchanger found in endosomes, appears to influence the differentiation of T cells to a proinflammatory fate and may have a broader role in MS disease activity, outside of IFNβ treatment.	0.128957582	2015	SLC9A9	3	143707136	G	A
rs9891119	21833088	6774	STAT3	umls:C0026769	GWASCAT	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	0.127915422	2011	STAT3	17	42355962	A	C
rs9939609	24532085	79068	FTO	umls:C0026769	BeFree	The fat mass and obesity-associated FTO rs9939609 polymorphism is associated with elevated homocysteine levels in patients with multiple sclerosis screened for vascular risk factors.	0.000271442	2014	FTO	16	53786615	T	A

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:1267)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
1	2526746	rs3748816	A	G	rs3748816	21833088	1.60E-12	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	2526746	rs3748816	A	G	rs3748816	22190364	3.28E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	2709164	rs4648356	C	A	rs4648356	21833088	1.00E-14	NA	1.14	[1.12-1.16]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	10353112	rs10492972	T	C	rs10492972	18997785	3.00E-10	NA	1.34	[1.23-1.48]	45 cases; 195 controls	NOPOP(240)	ALL(240)	NOPOP(240)	ALL(240)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	20227723	rs4654925	G	C,T	rs4654925	22190364	9.00E-22	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	25303576	rs10903122	A	G	rs10903122	22190364	1.73E-10	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	26899125	rs282177	C	T	rs282177	17660530	6.39E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	33350183	rs11811702	G	A	rs11811702	19525953	5.82E-06	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	40301897	rs230275	G	C	rs230275	18195134	1.00E-04	Response to interferon beta therapy in multiple sclerosis (responders vs nonresponders)	NA	NA	206 Southern European multiple sclerosis cases	Southern European(206)	ALL(206)	EUR(206)	ALL(206)	Response to interferon beta in multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	40955156	rs10789144	A	T	rs10789144	17660530	6.64E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	46223086	rs11211176	G	A	rs11211176	17660530	6.48E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	52417538	rs2809944	T	C	rs2809944	20598377	6.91E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	56102010	rs17418151	C	G	rs17418151	17660530	6.84E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	67694202	rs2201841	A	G	rs2201841	22190364	1.30E-13	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	67702526	rs11465804	T	G	rs11465804	22190364	6.66E-63	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	71366238	rs1327464	G	A	rs1327464	18195134	1.00E-04	Response to interferon beta therapy in multiple sclerosis (responders vs nonresponders)	NA	NA	206 Southern European multiple sclerosis cases	Southern European(206)	ALL(206)	EUR(206)	ALL(206)	Response to interferon beta in multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	77072458	rs2647389	T	C	rs2647389	17660530	3.60E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	77749363	rs7517698	G	A,C	rs7517698	17660530	5.75E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	85772009	rs233100	G	A	rs233100	21833088	1.00E-06	NA	1.08	[1.07-1.10]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	92224347	rs11165441	G	A	rs11165441	19525953	3.01E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	92947138	rs11164607	A	C	rs11164607	17660530	7.72E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	92975493	rs4970700	A	G	rs4970700	17660530	2.31E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93037112	rs12743520	C	A	rs12743520	17660530	4.78E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93073228	rs11808092	C	A	rs11808092	19525955	1.50E-05	NA	NA	NA	1,618 European ancestry cases; 3,413 European ancestry controls	European(5031)	ALL(5031)	EUR(5031)	ALL(5031)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93090476	rs1415296	G	C	rs1415296	17660530	7.17E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93121107	rs10735781	G	C	rs10735781	17660530	1.68E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93121107	rs10735781	G	C	rs10735781	19525953	7.55E-06	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93121107	rs10735781	G	C	rs10735781	21833088	4.50E-09	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93127927	rs11800848	A	C	rs11800848	17660530	2.88E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93148377	rs11810217	C	T	rs11810217	21833088	6.00E-15	NA	1.15	[1.13-1.16]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93148377	rs11810217	C	T	rs11810217	24234648	3.20E-04	NA	1.14	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93155347	rs4847267	C	T	rs4847267	17660530	3.61E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93160002	rs34202284	G	A	rs34202284	17660530	4.49E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93176878	rs6680578	T	A	rs6680578	17660530	2.08E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93261373	rs11164814	A	G	rs11164814	19525953	1.99E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93303603	rs6604026	T	C	rs6604026	17660530	8.00E-06	NA	1.15	[1.08-1.22]	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93303603	rs6604026	T	C	rs6604026	19525955	3.00E-06	NA	1.17	NA	1,618 European ancestry cases; 3,413 European ancestry controls	European(5031)	ALL(5031)	EUR(5031)	ALL(5031)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93320869	rs7514280	C	T	rs7514280	17660530	7.08E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93323971	rs10874746	T	C	rs10874746	17660530	1.09E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93334138	rs2811600	C	T	rs2811600	17660530	1.71E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93346928	rs35183060	A	T	rs35183060	17660530	4.91E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93349046	rs7536563	A	G	rs7536563	17660530	2.27E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93368309	rs2255723	G	T	rs2255723	17660530	1.11E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93379093	rs11164835	G	A	rs11164835	17660530	5.36E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93385136	rs9651257	T	C	rs9651257	17660530	3.40E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93395378	rs11164838	C	T	rs11164838	17660530	6.01E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93401837	rs12745968	A	G	rs12745968	17660530	8.01E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93402551	rs17380908	C	T	rs17380908	17660530	5.74E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93445497	rs521428	G	A	rs521428	17660530	2.12E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93468062	rs532834	A	T	rs532834	17660530	1.82E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	93474165	rs496465	A	G	rs496465	17660530	9.75E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	101331536	rs12048904	T	C	rs12048904	21833088	4.00E-08	Conditioned on rs11581062	1.09	[1.08-1.11]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	101407519	rs11581062	A	G	rs11581062	21833088	3.00E-10	NA	1.12	[1.10-1.13]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	104446782	rs1182580	C	T	rs1182580	19525953	2.37E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	104452958	rs41419745	T	A	rs41419745	17660530	4.41E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	104476678	rs11185337	C	A	rs11185337	17660530	3.49E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	104986052	rs11184173	C	T	rs11184173	20802204	2.99E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
1	110864149	rs4838992	A	G	rs4838992	17660530	6.17E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	114303808	rs6679677	C	A	rs6679677	22190364	8.00E-24	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	114377568	rs2476601	A	G	rs2476601	22190364	3.40E-12	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	117038287	rs12025416	T	C	rs12025416	19525953	1.16E-09	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	117038287	rs12025416	T	C	rs12025416	21244703	1.00E-07	NA	1.45	[1.25-1.69]	2,124 cases; 6,720 controls	NOPOP(8844)	ALL(8844)	NOPOP(8844)	ALL(8844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	117087779	rs12044852	C	A	rs12044852	17660530	1.90E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	117100957	rs1335532	A	G	rs1335532	19525955	1.00E-07	NA	1.28	NA	1,618 European ancestry cases; 3,413 European ancestry controls	European(5031)	ALL(5031)	EUR(5031)	ALL(5031)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	117100957	rs1335532	A	G	rs1335532	21833088	3.00E-16	NA	1.22	[1.19-1.24]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	117100957	rs1335532	A	G	rs1335532	22190364	1.51E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	117100957	rs1335532	A	G	rs1335532	24234648	1.20E-08	NA	1.35	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	117104215	rs2300747	A	G	rs2300747	19525953	3.00E-10	NA	1.3	[1.14-1.47]	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	117104215	rs2300747	A	G	rs2300747	21833088	4.40E-10	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	117104215	rs2300747	A	G	rs2300747	22190364	6.00E-09	NA	1.37	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	117263138	rs11586238	C	G	rs11586238	22190364	1.00E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	152550018	rs4085613	T	G	rs4085613	22190364	7.00E-30	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	157669278	rs3761959	C	T	rs3761959	21833088	3.00E-06	NA	1.08	[1.06-1.09]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	159818513	rs6659742	C	T	rs6659742	23472185	7.00E-07	OCB negative vs. controls	1.99	[1.52-2.61]	1,367 European ancestry OCB positive cases; 161 European ancestry OCB negative cases; 428 European ancestry controls	European(1956)	ALL(1956)	EUR(1956)	ALL(1956)	Multiple sclerosis (OCB status)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
1	160852046	rs2274910	T	C	rs2274910	22190364	1.46E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	161472158	rs10800309	A	G	rs10800309	22190364	2.80E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	164447212	rs1538370	A	G	rs1538370	19010793	2.69E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
1	172346548	rs1011731	G	A	rs1011731	17660530	9.58E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	172862234	rs9286879	A	G	rs9286879	22190364	1.53E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	173191475	rs2205960	G	T	rs2205960	22190364	6.30E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	173284199	rs4916321	G	T	rs4916321	23412934	7.00E-06	Cluxel size	NA	NA	284 European ancestry individuals	European(284)	ALL(284)	EUR(284)	ALL(284)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	179469314	rs12047808	A	G	rs12047808	19010793	6.00E-06	NA	NA	NA	978 European ancestry cases; 883 European ancestry controls	European(1861)	ALL(1861)	EUR(1861)	ALL(1861)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
1	179525311	rs745317	C	T	rs745317	19010793	2.88E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
1	182549019	rs533259	A	G	rs533259	23412934	6.00E-09	Cluxel size	NA	NA	284 European ancestry individuals	European(284)	ALL(284)	EUR(284)	ALL(284)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	190813289	rs10494649	T	C	rs10494649	18195134	2.00E-04	Response to interferon beta therapy in multiple sclerosis (responders vs nonresponders)	NA	NA	206 Southern European multiple sclerosis cases	Southern European(206)	ALL(206)	EUR(206)	ALL(206)	Response to interferon beta in multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	192492895	rs10754012	A	G	rs10754012	17660530	1.96E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	192530548	rs2760524	A	G	rs2760524	17660530	5.17E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	192530548	rs2760524	A	G	rs2760524	19525953	9.77E-06	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	192530548	rs2760524	A	G	rs2760524	21833088	1.60E-06	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	192536813	rs2816316	C	A	rs2816316	22190364	2.20E-17	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	192541021	rs1323292	G	A	rs1323292	21833088	2.00E-08	NA	1.12	[1.10-1.14]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	192541472	rs1359062	C	G	rs1359062	17660530	5.88E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	200881595	rs7522462	G	A	rs7522462	21833088	2.00E-09	NA	1.11	[1.10-1.13]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	200881595	rs7522462	G	A	rs7522462	24234648	8.30E-04	NA	1.13	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	200892137	rs296547	T	C	rs296547	22190364	4.11E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	200935866	rs11584383	T	C	rs11584383	22190364	1.43E-11	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	200984480	rs12122721	G	A	rs12122721	21833088	1.00E-06	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	206939904	rs3024505	G	A	rs3024505	22190364	4.00E-08	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	208278877	rs12083980	C	T	rs12083980	19010793	8.71E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
1	208279228	rs11118986	G	A	rs11118986	19010793	5.89E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
1	208662959	rs841503	C	A	rs841503	17660530	2.50E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	208897416	rs1166879	C	T	rs1166879	19010793	5.01E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
1	210354442	rs12567108	G	A	rs12567108	20802204	2.26E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
1	222763661	rs2936040	T	A	rs2936040	17660530	1.45E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
1	230436520	rs1386584	A	G	rs1386584	20802204	2.48E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
1	233624614	rs4233060	G	A	rs4233060	19010793	2.57E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
1	240639611	rs9729366	A	G	rs9729366	20802204	2.62E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
2	4974780	rs12464103	G	A	rs12464103	19010793	2.63E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
2	8053597	rs4669226	A	G	rs4669226	23412934	5.00E-06	Cluxel size	NA	NA	284 European ancestry individuals	European(284)	ALL(284)	EUR(284)	ALL(284)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	9250038	rs1109670	C	A	rs1109670	19010793	9.00E-06	NA	1.38	NA	978 European ancestry cases; 883 European ancestry controls	European(1861)	ALL(1861)	EUR(1861)	ALL(1861)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	12676426	rs13013085	G	A	rs13013085	17660530	3.75E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	16243192	rs4668486	A	C	rs4668486	19525953	4.33E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	23506782	rs1438131	G	A	rs1438131	17660530	8.06E-10	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	28320033	rs7572644	T	C	rs7572644	17660530	5.10E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	28380295	rs4666040	A	G	rs4666040	17660530	8.34E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	29251134	rs17007460	C	T	rs17007460	20802204	4.99E-06	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
2	29876343	rs7577363	G	A	rs7577363	17660530	7.37E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	38021498	rs867574	T	C	rs867574	20598377	4.42E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	38820522	rs6544170	T	C	rs6544170	20598377	7.16E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	43325570	rs6718520	A	G	rs6718520	22190364	3.00E-08	NA	1.17	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	43325570	rs6718520	A	G	rs6718520	24234648	1.20E-05	NA	1.16	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	43359061	rs12466022	C	A	rs12466022	21833088	6.00E-10	NA	1.11	[1.10-1.13]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	43359061	rs12466022	C	A	rs12466022	24234648	4.20E-05	NA	1.16	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	51059836	rs17569702	T	C	rs17569702	20802204	3.15E-06	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
2	51095053	rs1558799	G	A	rs1558799	20802204	2.65E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
2	53931190	rs7583622	G	A	rs7583622	17660530	5.26E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	54053872	rs698853	A	G	rs698853	17660530	7.11E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	54305030	rs41385746	T	C	rs41385746	17660530	6.33E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	54308826	rs34498089	A	G	rs34498089	17660530	3.13E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	54333729	rs17039547	A	C	rs17039547	17660530	4.57E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	60131157	rs1019614	A	G	rs1019614	19010793	2.57E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
2	60159532	rs7576017	A	G	rs7576017	19010793	3.98E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
2	60159756	rs12468914	T	C	rs12468914	19010793	8.13E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
2	60202239	rs4672335	G	A	rs4672335	19010793	1.78E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
2	60235568	rs11896330	G	A	rs11896330	19010793	7.59E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
2	60241822	rs4672341	C	A	rs4672341	19010793	3.98E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
2	61164331	rs13017599	G	A	rs13017599	22190364	2.00E-12	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	61186829	rs13003464	A	G	rs13003464	22190364	3.71E-13	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	65595586	rs934734	G	A	rs934734	22190364	5.30E-10	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	66504005	rs11689807	A	G	rs11689807	19010793	3.31E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
2	68598955	rs17035378	T	C	rs17035378	22190364	7.79E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	68646783	rs7592330	G	A	rs7592330	22190364	2.00E-07	NA	1.15	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	68647095	rs7595037	C	T	rs7595037	21833088	5.00E-11	NA	1.11	[1.10-1.12]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	68647095	rs7595037	C	T	rs7595037	24234648	1.60E-05	NA	1.15	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	70151471	rs10205487	A	G	rs10205487	17660530	5.02E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	71830689	rs1529409	T	C	rs1529409	17660530	1.40E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	75720372	rs11126472	C	T	rs11126472	20802204	2.34E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
2	80192435	rs2861913	A	G	rs2861913	17660530	1.12E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	100806940	rs11676922	T	A	rs11676922	22190364	1.00E-14	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	103070568	rs917997	T	C	rs917997	22190364	1.11E-15	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	112665201	rs17174870	C	T	rs17174870	21833088	1.00E-08	NA	1.11	[1.09-1.13]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	112665201	rs17174870	C	T	rs17174870	24234648	1.20E-04	NA	1.15	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	119395691	rs651477	T	C	rs651477	19010793	7.00E-06	NA	1.38	NA	978 European ancestry cases; 883 European ancestry controls	European(1861)	ALL(1861)	EUR(1861)	ALL(1861)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	129489556	rs6744496	G	A	rs6744496	17660530	1.37E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	133746630	rs1437898	A	C	rs1437898	19010793	8.00E-06	NA	NA	NA	978 European ancestry cases; 883 European ancestry controls	European(1861)	ALL(1861)	EUR(1861)	ALL(1861)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
2	134230217	rs1821625	G	T	rs1821625	23412934	7.00E-06	Cluxel size	NA	NA	284 European ancestry individuals	European(284)	ALL(284)	EUR(284)	ALL(284)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	135068794	rs4953911	T	A	rs4953911	20117844	2.00E-07	Multiple sclerosis (severity)	NA	NA	1040 cases	NOPOP(1040)	ALL(1040)	NOPOP(1040)	ALL(1040)	Multiple sclerosis (severity)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
2	136976255	rs882300	T	C	rs882300	19525953	1.00E-07	NA	1.19	[1.09-1.30]	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	151291604	rs2334310	A	C	rs2334310	19010793	5.37E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
2	163124051	rs1990760	C	T	rs1990760	22190364	2.00E-11	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	168840454	rs9287889	C	T	rs9287889	18195134	9.00E-04	Response to interferon beta therapy in multiple sclerosis (responders vs nonresponders)	NA	NA	206 Southern European multiple sclerosis cases	Southern European(206)	ALL(206)	EUR(206)	ALL(206)	Response to interferon beta in multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	179296271	rs9283487	T	C	rs9283487	23472185	3.00E-07	OCB positive vs. controls	1.61	[1.33-1.92]	1,367 European ancestry OCB positive cases; 161 European ancestry OCB negative cases; 428 European ancestry controls	European(1956)	ALL(1956)	EUR(1956)	ALL(1956)	Multiple sclerosis (OCB status)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
2	181042370	rs7597201	T	G	rs7597201	23785401	4.31E-04	NA	1.75	NA	49 European ancestry OCB negative cases; 513 European ancestry OCB positive cases	European(562)	ALL(562)	EUR(562)	ALL(562)	Multiple sclerosis (OCB status)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
2	181996045	rs13010713	A	G	rs13010713	22190364	4.74E-11	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	183760854	rs7606391	A	C	rs7606391	19010793	8.13E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
2	187225386	rs10497669	G	A	rs10497669	19010793	7.59E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
2	187489647	rs12620429	C	A	rs12620429	19010793	9.55E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
2	191964633	rs7574865	T	G	rs7574865	22190364	1.40E-41	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	200751582	rs281783	G	A	rs281783	21833088	1.80E-04	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	204455370	rs10191601	C	T	rs10191601	19525953	1.02E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	204610396	rs1980422	C	T	rs1980422	22190364	1.80E-08	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	204738919	rs3087243	G	A	rs3087243	22190364	8.00E-11	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	204802578	rs4675374	T	C	rs4675374	22190364	5.79E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	205578015	rs41482445	C	T	rs41482445	17660530	2.19E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	205627933	rs17113	C	G	rs17113	17660530	1.56E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	209135339	rs6746926	G	A	rs6746926	19010793	4.57E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
2	209204714	rs2289171	G	A	rs2289171	19010793	1.17E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
2	209235373	rs4673402	G	A	rs4673402	19010793	6.92E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
2	209239742	rs4675764	G	A	rs4675764	19010793	3.98E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
2	209412884	rs10932263	G	A	rs10932263	19010793	1.86E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
2	212697542	rs16846917	G	T	rs16846917	20802204	1.54E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
2	212715410	rs1159709	T	C	rs1159709	20802204	1.17E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
2	220848941	rs7608541	G	A	rs7608541	19010793	3.89E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
2	231106724	rs10201872	C	T	rs10201872	21833088	2.00E-10	NA	1.14	[1.12-1.16]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	231106724	rs10201872	C	T	rs10201872	24234648	5.60E-04	NA	1.15	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	234180410	rs3828309	A	G	rs3828309	22190364	2.36E-32	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
2	234504098	rs1597944	C	T	rs1597944	19010793	4.00E-06	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
2	234504098	rs1597944	C	T	rs2602397	19010793	4.00E-06	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Normalized brain volume	HPOID:0002011	Abnormality of the central nervous system	DOID:2377	multiple sclerosis	D009103	Multiple Sclerosis	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
3	1257668	rs7644569	C	T	rs7644569	19010793	6.03E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
3	1655984	rs417975	T	C	rs417975	20802204	2.09E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
3	4437358	rs794185	T	C	rs794185	20802204	6.00E-07	NA	NA	NA	382 cases	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
3	7539974	rs3804945	A	G	rs3804945	17660530	1.93E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	14496162	rs11128699	G	A	rs11128699	19010793	4.47E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
3	16970938	rs9821630	A	G	rs9821630	21833088	4.00E-06	NA	1.08	[1.07-1.10]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	27788780	rs11129295	C	T	rs11129295	21833088	1.00E-09	Conditioned on rs669607	1.11	[1.09-1.12]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	28071444	rs669607	A	C	rs669607	21833088	2.00E-15	NA	1.13	[1.12-1.15]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	28071444	rs669607	A	C	rs669607	24234648	2.50E-05	NA	1.15	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	28079085	rs170934	C	T	rs170934	22190364	2.00E-08	NA	1.17	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	33015469	rs13314993	G	T	rs13314993	22190364	3.27E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	37224099	rs1053006	G	A	rs1053006	20802204	3.06E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
3	46235201	rs13098911	C	T	rs13098911	22190364	3.26E-17	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	49721532	rs3197999	G	A	rs3197999	22190364	1.15E-12	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	50609624	rs2232248	T	A,C,G	rs2232248	20802204	2.04E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
3	56914065	rs1500710	C	A	rs1500710	21833088	5.20E-05	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	58370177	rs6445975	G	T	rs6445975	22190364	7.10E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	58556841	rs13315591	T	C	rs13315591	22190364	4.60E-08	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	58614420	rs753821	G	A	rs753821	17660530	7.35E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	60171660	rs9876685	T	C	rs9876685	23785401	6.29E-05	NA	3.13	NA	49 European ancestry OCB negative cases; 513 European ancestry OCB positive cases	European(562)	ALL(562)	EUR(562)	ALL(562)	Multiple sclerosis (OCB status)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
3	61021239	rs2365045	G	A	rs2365045	17660530	8.21E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	68458440	rs4855469	C	T	rs4855469	18195134	3.00E-04	Response to interferon beta therapy in multiple sclerosis (responders vs nonresponders)	NA	NA	206 Southern European multiple sclerosis cases	Southern European(206)	ALL(206)	EUR(206)	ALL(206)	Response to interferon beta in multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	76775169	rs267122	T	A	rs267122	17660530	8.52E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	76775597	rs267120	G	T	rs267120	17660530	6.10E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	85989000	rs9861174	G	T	rs9861174	19010793	8.51E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
3	86065598	rs9829960	A	G	rs9829960	19010793	4.37E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
3	97355029	rs10222570	C	T	rs10222570	23785401	3.01E-04	NA	1.61	NA	49 European ancestry OCB negative cases; 513 European ancestry OCB positive cases	European(562)	ALL(562)	EUR(562)	ALL(562)	Multiple sclerosis (OCB status)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
3	97388193	rs1658146	G	A	rs1658146	19010793	6.31E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
3	97411617	rs301923	A	G	rs301923	19010793	7.41E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
3	101748638	rs771767	A	G	rs771767	21833088	9.00E-09	NA	1.1	[1.09-1.12]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	105558837	rs2028597	G	A	rs2028597	21833088	7.20E-04	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	105586714	rs9657904	T	C	rs9657904	20453840	2.00E-10	NA	1.4	[1.27-1.57]	882 Sardinian cases; 872 Sardinian controls	Sardinian(1754)	ALL(1754)	EUR(1754)	ALL(1754)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	105912130	rs12487066	T	C	rs12487066	17660530	4.09E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	105912175	rs12487092	T	G	rs12487092	17660530	4.35E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	105913278	rs12695132	G	C,T	rs12695132	17660530	4.78E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	107722134	rs6798831	T	C	rs6798831	21833088	2.40E-06	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	109034120	rs11712428	G	T	rs11712428	19010793	2.00E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
3	114821299	rs2177041	A	C	rs2177041	20802204	4.58E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
3	119118796	rs11712165	T	G	rs11712165	22190364	8.03E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	119150836	rs1132200	C	T	rs1132200	21833088	7.00E-07	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	119219934	rs2293370	G	A	rs2293370	21833088	3.00E-09	NA	1.13	[1.11-1.15]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	121660664	rs4285028	A	C	rs4285028	21833088	2.00E-08	Conditioned on rs9282641	1.1	[1.09-1.12]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	121769522	rs2681424	T	C	rs2681424	22190364	2.00E-07	NA	1.16	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	121793187	rs4308217	C	A,T	rs4308217	21833088	6.00E-08	(Conditioned on rs4285028, rs9282641)	1.1	[1.08-1.11]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	121796768	rs9282641	G	A	rs9282641	21833088	1.00E-11	NA	1.21	[1.18-1.24]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	131433077	rs995540	C	T	rs995540	17660530	4.64E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	132401600	rs6794496	C	T	rs6794496	19010793	1.58E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
3	140099693	rs17411949	C	T	rs17411949	23472185	8.00E-07	NA	1.85	[1.45-2.37]	1,367 European ancestry OCB positive cases; 161 European ancestry OCB negative cases; 428 European ancestry controls	European(1956)	ALL(1956)	EUR(1956)	ALL(1956)	Multiple sclerosis (OCB status)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
3	140540718	rs908821	A	G	rs908821	19010793	3.00E-06	NA	1.37	NA	978 European ancestry cases; 883 European ancestry controls	European(1861)	ALL(1861)	EUR(1861)	ALL(1861)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	147756686	rs1841770	G	T	rs1841770	19010793	8.00E-06	NA	1.34	NA	978 European ancestry cases; 883 European ancestry controls	European(1861)	ALL(1861)	EUR(1861)	ALL(1861)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	154183562	rs1356122	G	C	rs1356122	17660530	5.39E-16	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	156626091	rs12638253	C	T	rs12638253	19010793	2.00E-06	NA	NA	NA	794 European ancestry cases; 883 European ancestry controls	European(1677)	ALL(1677)	EUR(1677)	ALL(1677)	Multiple sclerosis (severity)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
3	159665050	rs17810546	A	G	rs17810546	22190364	3.98E-28	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	159698945	rs4680534	T	C	rs4680534	19525953	6.00E-06	NA	1.12	[1.02-1.22]	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	159698945	rs4680534	T	C	rs4680534	21833088	3.60E-05	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	159698945	rs4680534	T	C	rs4680534	22190364	3.28E-05	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	159709651	rs2243123	T	C	rs2243123	21833088	7.00E-06	NA	1.08	[1.06-1.10]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	161949284	rs1488583	G	A	rs1488583	20802204	1.32E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
3	163223847	rs1599271	T	G	rs1599271	20802204	2.14E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
3	169283495	rs3863105	T	C	rs3863105	19010793	9.55E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
3	169492101	rs10936599	C	T	rs10936599	21833088	7.00E-07	NA	1.1	[1.08-1.11]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	186191696	rs7610178	C	T	rs7610178	19010793	8.91E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
3	186293588	rs2280391	A	G	rs2280391	17660530	8.33E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	186298381	rs9840074	G	A	rs9840074	17660530	2.07E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	188112554	rs1464510	C	A,G,T	rs1464510	22190364	2.98E-40	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	188491558	rs6808275	A	G	rs6808275	20598377	2.94E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	188495948	rs1546736	G	A	rs1546736	20598377	6.11E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
3	191239571	rs10937486	T	G	rs10937486	21833088	5.90E-06	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	4654357	rs2063413	T	C	rs2063413	20802204	2.64E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
4	10142366	rs10028937	A	G	rs10028937	17660530	5.40E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	19110954	rs9684799	C	T	rs9684799	17660530	5.40E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	20440476	rs6849536	T	C	rs6849536	19010793	2.63E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
4	26085511	rs10517086	G	A	rs10517086	22190364	4.60E-10	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	26108197	rs874040	G	C	rs874040	22190364	1.00E-16	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	30646834	rs6448715	G	C	rs6448715	17660530	5.61E-08	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	30834962	rs1447372	T	C	rs1447372	17660530	1.05E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	37064331	rs13117816	G	T	rs13117816	20802204	7.00E-06	NA	NA	NA	382 cases	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
4	41234424	rs11722918	C	T	rs11722918	19010793	4.90E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
4	57172335	rs11736632	G	A	rs11736632	19525953	4.59E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	63255019	rs778959	C	A	rs778959	19010793	7.94E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
4	68064440	rs10518025	T	C	rs10518025	19010793	4.00E-06	NA	NA	NA	794 European ancestry cases; 883 European ancestry controls	European(1677)	ALL(1677)	EUR(1677)	ALL(1677)	Multiple sclerosis (severity)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
4	85249487	rs1390088	C	A	rs1390088	17660530	4.34E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	85273102	rs2868879	C	G	rs2868879	17660530	2.10E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	102081357	rs1880943	C	T	rs1880943	17660530	6.50E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	102082033	rs2695217	A	G	rs2695217	17660530	8.28E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	102751076	rs10516487	G	A	rs10516487	22190364	3.70E-10	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	103578637	rs228614	G	A	rs228614	21833088	1.00E-07	NA	1.09	[1.07-1.10]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	109953214	rs794143	A	G	rs794143	18195134	2.00E-04	Response to interferon beta therapy in multiple sclerosis (responders vs nonresponders)	NA	NA	206 Southern European multiple sclerosis cases	Southern European(206)	ALL(206)	EUR(206)	ALL(206)	Response to interferon beta in multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	123019620	rs10015924	T	C	rs10015924	17660530	2.31E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	123115502	rs13151961	A	G	rs13151961	22190364	2.18E-27	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	123329362	rs17388568	G	A	rs17388568	22190364	1.87E-08	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	123509421	rs6822844	G	T	rs6822844	22190364	1.64E-10	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	131790501	rs1478091	C	T	rs1478091	19010793	2.00E-06	NA	NA	NA	794 European ancestry cases; 883 European ancestry controls	European(1677)	ALL(1677)	EUR(1677)	ALL(1677)	Multiple sclerosis (severity)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
4	140882750	rs769673	G	A	rs769673	20598377	2.14E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	154154000	rs12644284	A	G	rs12644284	21654844	4.00E-06	Extreme	2.04	NA	1,470 European ancestry cases	European(1470)	ALL(1470)	EUR(1470)	ALL(1470)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	166362750	rs1898593	G	T	rs1898593	19010793	3.89E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
4	166830364	rs12513380	G	A	rs12513380	23412934	5.00E-06	Cluxel size	NA	NA	284 European ancestry individuals	European(284)	ALL(284)	EUR(284)	ALL(284)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	174802918	rs4600896	A	G	rs4600896	17660530	1.28E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	179380467	rs1903524	A	G	rs1903524	19010793	4.47E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
4	180667647	rs17090640	G	A	rs17090640	23412934	3.00E-06	Cluxel size	NA	NA	284 European ancestry individuals	European(284)	ALL(284)	EUR(284)	ALL(284)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	182399695	rs7672826	G	A	rs7672826	19010793	8.00E-06	NA	1.37	NA	978 European ancestry cases; 883 European ancestry controls	European(1861)	ALL(1861)	EUR(1861)	ALL(1861)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	183132303	rs1031313	C	T	rs1031313	19010793	9.77E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
4	186571441	rs6821894	C	T	rs6821894	21833088	9.20E-05	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
4	189144306	rs11734807	C	G	rs11734807	17660530	1.04E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	583442	rs4957048	G	A	rs4957048	22190364	1.20E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	5222336	rs4702248	A	G	rs4702248	19010793	2.00E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
5	5223923	rs4702249	T	C	rs4702249	19010793	1.82E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
5	8889910	rs2962694	T	A	rs2962694	17660530	1.46E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	8908533	rs2963341	G	C	rs2963341	17660530	4.84E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	8960917	rs13359910	C	T	rs13359910	17660530	2.41E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	8961561	rs9313264	C	T	rs9313264	17660530	1.19E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	8977866	rs6555588	A	G	rs6555588	17660530	1.01E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	10998665	rs706306	T	C	rs706306	17660530	3.23E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	31992572	rs6861526	T	C	rs6861526	17660530	1.51E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	35803577	rs931555	C	T	rs931555	19525953	1.87E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	35803577	rs931555	C	T	rs931555	21244703	4.00E-07	NA	1.25	[1.15-1.36]	2,124 cases; 6,720 controls	NOPOP(8844)	ALL(8844)	NOPOP(8844)	ALL(8844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	35874575	rs6897932	C	T	rs6897932	17660530	3.00E-07		1.18	[1.11-1.26]	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	35874575	rs6897932	C	T	rs6897932	19525953	2.00E-06	NA	1.12	[1.02-1.23]	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	35874575	rs6897932	C	T	rs6897932	21833088	2.00E-08	NA	1.11	[1.09-1.13]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	35874575	rs6897932	C	T	rs6897932	22190364	7.70E-04	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	37986493	rs1304732	C	T	rs1304732	19010793	9.77E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
5	38743568	rs4869598	C	T	rs4869598	19010793	8.91E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
5	39441157	rs10512706	T	A	rs10512706	18195134	1.00E-04	Response to interferon beta therapy in multiple sclerosis (responders vs nonresponders)	NA	NA	206 Southern European multiple sclerosis cases	Southern European(206)	ALL(206)	EUR(206)	ALL(206)	Response to interferon beta in multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	39960584	rs10473156	C	A	rs10473156	20802204	1.89E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
5	39990417	rs9292757	G	A	rs9292757	20802204	1.28E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
5	40211802	rs350058	G	A	rs350058	21833088	1.00E-04	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	40392728	rs4613763	T	C	rs4613763	21833088	3.00E-16	NA	1.2	[1.18-1.22]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	40392728	rs4613763	T	C	rs4613763	22190364	6.82E-27	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	40392728	rs4613763	T	C	rs4613763	24234648	1.40E-04	NA	1.19	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	40424426	rs6896969	A	C	rs6896969	19525953	2.00E-07	NA	1.1	[1.01-1.20]	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	40424426	rs6896969	A	C	rs6896969	21833088	7.50E-10	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	40437948	rs9292777	C	T	rs9292777	22570697	1.00E-09	NA	1.19	[1.12-1.25]	2,127 European ancestry cases; 4,558 European ancestry controls	European(6685)	ALL(6685)	EUR(6685)	ALL(6685)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	41802771	rs12186512	A	G	rs12186512	19010793	5.37E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
5	55438580	rs6859219	C	A	rs6859219	22190364	9.60E-12	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	55857675	rs4301182	A	C	rs4301182	17660530	1.19E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	82985739	rs4466137	T	G	rs4466137	18195134	2.00E-04	Response to interferon beta therapy in multiple sclerosis (responders vs nonresponders)	NA	NA	206 Southern European multiple sclerosis cases	Southern European(206)	ALL(206)	EUR(206)	ALL(206)	Response to interferon beta in multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	91942698	rs7709237	A	G	rs7709237	17660530	3.17E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	95198252	rs154447	G	A	rs154447	17660530	9.21E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	100132577	rs32477	C	G	rs32477	17660530	1.79E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	102596720	rs26232	C	T	rs26232	22190364	4.10E-08	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	104028909	rs576547	G	A	rs576547	19010793	9.77E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
5	106861975	rs395561	A	C	rs395561	17660530	1.69E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	118731067	rs1105769	A	C	rs1105769	17660530	1.20E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	118731247	rs1105770	T	G	rs1105770	17660530	7.24E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	131770805	rs2188962	C	T	rs2188962	22190364	2.32E-18	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	131995964	rs20541	A	G	rs20541	22190364	5.00E-15	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	133446575	rs756699	C	T	rs756699	21833088	6.00E-07	NA	1.12	[1.10-1.14]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	136846053	rs4246794	C	T	rs4246794	17660530	5.06E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	140955777	rs2302103	C	T	rs2302103	21833088	5.40E-04	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	141523000	rs1062158	C	T	rs1062158	21833088	2.00E-06	NA	1.08	[1.07-1.10]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	150258867	rs11747270	A	G	rs11747270	22190364	3.40E-16	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	150431030	rs888989	C	T	rs888989	20598377	2.74E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	150457485	rs7708392	G	C	rs7708392	22190364	3.80E-13	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	150478318	rs17728338	G	A	rs17728338	22190364	1.00E-20	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	155471714	rs6556352	C	T	rs6556352	19010793	5.01E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
5	155500992	rs4704970	G	A	rs4704970	19010793	7.00E-06	NA	NA	NA	978 European ancestry cases; 883 European ancestry controls	European(1861)	ALL(1861)	EUR(1861)	ALL(1861)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
5	155746538	rs6875001	A	G	rs6875001	19010793	6.76E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
5	158717789	rs2082412	G	A	rs2082412	22190364	2.00E-28	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	158759900	rs2546890	A	G	rs2546890	21833088	1.00E-11	NA	1.11	[1.10-1.13]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	158759900	rs2546890	A	G	rs2546890	22190364	8.00E-08	NA	1.16	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	158759900	rs2546890	A	G	rs2546890	24234648	3.80E-06	NA	1.16	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	158814533	rs10045431	A	C	rs10045431	22190364	3.86E-13	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	158822645	rs6887695	G	C	rs6887695	22190364	4.08E-10	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	158918894	rs10866713	G	A	rs10866713	22190364	7.00E-07	NA	1.17	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	159879978	rs2431697	T	C	rs2431697	22190364	1.00E-10	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	164989544	rs1421784	T	C	rs1421784	18195134	2.00E-04	Response to interferon beta therapy in multiple sclerosis (responders vs nonresponders)	NA	NA	206 Southern European multiple sclerosis cases	Southern European(206)	ALL(206)	EUR(206)	ALL(206)	Response to interferon beta in multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	169270812	rs168678	A	G	rs168678	19010793	9.12E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
5	169950394	rs11957313	G	A	rs11957313	19010793	9.00E-06	NA	NA	NA	753 European ancestry cases; 883 European ancestry controls	European(1636)	ALL(1636)	EUR(1636)	ALL(1636)	Normalized brain volume	HPOID:0002011	Abnormality of the central nervous system	DOID:2377	multiple sclerosis	D009103	Multiple Sclerosis	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
5	176726002	rs4976682	T	C	rs4976682	19525953	2.56E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	176740244	rs11949767	A	G	rs11949767	17660530	5.29E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	176740996	rs6885410	C	A	rs6885410	17660530	5.27E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
5	176784512	rs4075958	G	A	rs4075958	21833088	5.00E-07	NA	1.09	[1.08-1.11]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	2680805	rs6939996	G	A	rs6939996	19010793	3.47E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
6	7118990	rs11755724	A	G	rs11755724	21833088	3.00E-06	NA	1.08	[1.06-1.09]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	15089151	rs6941421	T	C	rs6941421	19010793	6.00E-06	NA	NA	NA	794 European ancestry cases; 883 European ancestry controls	European(1677)	ALL(1677)	EUR(1677)	ALL(1677)	Multiple sclerosis (severity)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
6	20728731	rs6908425	T	C	rs6908425	22190364	8.96E-10	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	25413922	rs1543603	A	G	rs1543603	20802204	1.60E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
6	25422353	rs11968423	C	T	rs11968423	17660530	4.05E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29631744	rs3130252	C	T	rs3130252	17660530	3.46E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29675676	rs1610585	C	G	rs1610585	17660530	8.10E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29678520	rs1610593	A	C,G,T	rs1610593	17660530	8.54E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29692305	rs1632953	A	G	rs1632953	17660530	6.74E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29694427	rs1059174	C	T	rs1059174	17660530	7.46E-08	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29696209	rs1736921	G	A	rs1736921	17660530	1.12E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29698031	rs2735057	G	C	rs2735057	17660530	2.46E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29704083	rs1736916	C	T	rs1736916	17660530	1.05E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29704400	rs1736913	T	C	rs1736913	17660530	4.63E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29705659	rs2523393	A	G	rs2523393	19525953	1.00E-17	NA	1.28	[1.18-1.39]	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29708222	rs1610603	T	C	rs1610603	17660530	2.54E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29724147	rs1633070	T	C	rs1633070	17660530	1.11E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29724201	rs1633069	C	G	rs1633069	17660530	8.70E-08	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29725321	rs1737076	A	G	rs1737076	17660530	2.52E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29729286	rs1610630	C	T	rs1610630	17660530	1.96E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29730923	rs1737068	C	A	rs1737068	17660530	7.46E-08	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29732969	rs1737060	G	C	rs1737060	17660530	8.31E-08	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29733742	rs1737055	A	G	rs1737055	17660530	4.27E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29777911	rs1632971	T	C	rs1632971	17660530	9.76E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29835834	rs3094159	G	A	rs3094159	17660530	2.38E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29836239	rs3094157	C	G	rs3094157	17660530	2.19E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29836577	rs3132718	T	C	rs3132718	17660530	1.65E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29841021	rs3132712	A	G	rs3132712	17660530	1.52E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29915751	rs2735096	G	A	rs2735096	17660530	9.33E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29916505	rs417162	C	T	rs417162	17660530	3.37E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29917146	rs1655904	T	C	rs1655904	17660530	7.76E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29918436	rs2508037	T	C	rs2508037	17660530	8.60E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	29920332	rs9260489	T	G	rs9260489	22190364	1.00E-11	NA	1.21	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	30077229	rs2523990	A	G	rs2523990	17660530	1.31E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	30122575	rs2517646	C	T	rs2517646	17660530	1.23E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	30178287	rs3132671	C	T	rs3132671	17660530	5.21E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	30190640	rs3130391	C	T	rs3130391	17660530	5.45E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	30193513	rs3132666	A	G	rs3132666	17660530	5.75E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	30199512	rs1013518	G	A	rs1013518	17660530	2.49E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	30204526	rs2844780	G	T	rs2844780	17660530	1.86E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	30332146	rs3094055	C	G	rs3094055	17660530	4.93E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	30430520	rs2516675	T	C	rs2516675	17660530	9.85E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	30628082	rs3130000	A	G	rs3130000	17660530	2.38E-09	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	30772378	rs3094123	A	G	rs3094123	17660530	8.07E-10	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	30803254	rs3130649	A	T	rs3130649	17660530	3.92E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	30817866	rs3095350	A	G	rs3095350	17660530	3.97E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	30822413	rs3095345	C	T	rs3095345	17660530	6.37E-10	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	30914751	rs2517451	C	T	rs2517451	20598377	1.85E-06	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	30940387	rs2530710	T	C	rs2530710	17660530	3.01E-11	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	30940569	rs2530709	G	C	rs2530709	17660530	7.87E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	30950050	rs2844678	G	A	rs2844678	17660530	4.39E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	30955681	rs1634731	G	A	rs1634731	20598377	6.05E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	30991559	rs6903912	G	A	rs6903912	20598377	3.73E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31005726	rs2844670	G	A	rs2844670	20598377	1.61E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31013541	rs2517538	C	G	rs2517538	17660530	1.80E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31021017	rs4713429	C	G	rs4713429	17660530	6.71E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31021161	rs9262615	C	G	rs9262615	17660530	2.83E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31025479	rs9262635	A	G	rs9262635	17660530	7.97E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31025848	rs9262636	A	G	rs9262636	17660530	9.11E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31042608	rs2523881	T	G	rs2523881	17660530	9.87E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31042769	rs2523880	C	G	rs2523880	17660530	9.08E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31071547	rs9263597	A	G	rs9263597	17660530	2.52E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31080432	rs2233969	A	G	rs2233969	17660530	2.71E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31080471	rs1265052	T	C	rs1265052	17660530	2.22E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31080828	rs2233967	C	G	rs2233967	17660530	1.73E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31081838	rs3130975	C	T	rs3130975	17660530	1.79E-08	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31083813	rs3130981	T	C	rs3130981	17660530	5.07E-11	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31087133	rs3095324	C	T	rs3095324	17660530	2.36E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31087133	rs386579334	C	T	rs3095324	17660530	2.36E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31089631	rs111199278	C	T	rs3095314	17660530	5.15E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31089631	rs3095314	C	T	rs3095314	17660530	5.15E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31097183	rs3130558	C	G	rs3130558	17660530	7.43E-11	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31098832	rs3131009	G	A	rs3131009	17660530	1.26E-10	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31098832	rs528878831	G	A	rs3131009	17660530	1.26E-10	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31101674	rs3130564	C	T	rs3130564	17660530	2.09E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31105633	rs2074478	C	T	rs2074478	20598377	3.39E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31105891	rs2233952	A	G	rs2233952	20598377	3.07E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31113214	rs1265074	C	A	rs1265074	17660530	2.14E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31130078	rs2073723	T	C	rs2073723	17660530	2.69E-10	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31132085	rs3130933	T	C	rs3130933	20598377	3.21E-07	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31133509	rs2106074	G	A	rs2106074	17660530	1.33E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31135706	rs9263804	C	T	rs9263804	17660530	7.48E-11	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31136453	rs3130501	A	G	rs3130501	17660530	2.13E-10	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31136714	rs3132524	T	C	rs3132524	17660530	9.05E-11	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31161210	rs3095238	T	G	rs3095238	17660530	1.14E-18	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31165566	rs3094609	T	C	rs3094609	20598377	1.64E-07	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31176602	rs4516988	A	G	rs4516988	17660530	7.37E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31177915	rs3130952	G	A	rs3130952	17660530	1.19E-18	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31179033	rs9295965	T	C	rs9295965	17660530	1.58E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31206616	rs3130531	A	G	rs3130531	17660530	7.53E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31208340	rs3095250	C	T	rs3095250	17660530	6.83E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31208340	rs3095250	C	T	rs3095250	20598377	3.57E-06	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31208453	rs3130532	A	G	rs3130532	17660530	2.82E-18	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31209045	rs3130534	G	A	rs3130534	17660530	1.20E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31209510	rs3130712	C	T	rs3130712	20598377	6.18E-06	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31232111	rs3130542	A	G	rs3130542	20598377	2.33E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31243170	rs3132486	G	A	rs3132486	17660530	2.92E-09	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31245736	rs6906846	A	G	rs6906846	17660530	1.15E-09	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31247067	rs7382297	T	G	rs7382297	17660530	9.76E-19	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31247067	rs7382297	T	G	rs7382297	20598377	4.68E-08	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31266117	rs2524095	A	C	rs2524095	17660530	1.32E-09	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31266522	rs2524089	G	T	rs2524089	17660530	5.95E-10	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31272261	rs6457374	C	T	rs6457374	20598377	2.77E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31274245	rs6931332	A	G	rs6931332	20598377	1.21E-06	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31320810	rs2596503	A	G	rs2596503	20598377	9.78E-06	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31336250	rs2523535	A	G	rs2523535	17660530	5.24E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31336349	rs2523534	A	G	rs2523534	17660530	1.17E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31339086	rs41519045	G	A	rs2596437	17660530	1.19E-18	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31340433	rs2844558	C	T	rs2844558	17660530	1.27E-09	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31343604	rs5025315	A	G	rs5025315	17660530	4.59E-08	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31343862	rs5022119	T	A	rs5022119	17660530	1.67E-08	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31344273	rs2523638	T	C	rs2523638	17660530	4.63E-09	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31344294	rs3997982	T	A	rs3997982	17660530	4.88E-19	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31348022	rs2596571	G	C	rs2596571	17660530	1.57E-17	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31351035	rs2523485	T	C	rs2523485	17660530	5.80E-18	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31351242	rs3016013	G	A	rs3016013	17660530	2.74E-12	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31351442	rs3099848	A	T	rs3099848	17660530	1.45E-13	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31359648	rs2395485	T	C	rs2395485	17660530	5.45E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31360095	rs2596517	G	A	rs2596517	17660530	7.32E-18	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31412961	rs2596464	T	C	rs2596464	17660530	1.79E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31418700	rs2516460	T	G	rs2516460	17660530	4.61E-11	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31420500	rs3131622	T	G	rs3131622	17660530	7.73E-10	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31425499	rs3131621	A	G	rs3131621	17660530	3.12E-09	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31436581	rs2844507	T	C	rs2844507	17660530	1.59E-09	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31439063	rs2844505	C	T	rs2844505	20598377	2.40E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31446546	rs2248373	T	C	rs2248373	17660530	1.28E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31449022	rs2523650	T	C	rs2523650	17660530	1.34E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31449081	rs2904776	G	C	rs2904776	17660530	6.52E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31451476	rs2905747	A	G	rs2905747	17660530	7.07E-17	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31455834	rs9267247	A	C	rs9267247	17660530	1.92E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31484683	rs3131631	G	C	rs3131631	17660530	2.11E-18	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31488145	rs3130637	A	G	rs3130637	20598377	4.98E-06	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31490725	rs3093993	C	A	rs3093993	20598377	4.98E-06	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31491000	rs3095227	A	G	rs3095227	20598377	5.94E-06	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31494738	rs2734573	C	A	rs2734573	17660530	8.38E-11	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31496925	rs3093983	G	A	rs3093983	20598377	1.33E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31497835	rs3115537	G	C	rs3115537	17660530	1.74E-18	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31498497	rs3093978	C	A	rs3093978	20598377	9.28E-06	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31506744	rs2516393	A	C	rs2516393	20598377	1.14E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31586094	rs2736177	C	T	rs2736177	17660530	3.15E-23	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31590898	rs2736172	C	T	rs2736172	17660530	1.08E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31604044	rs3132453	T	G	rs3132453	20598377	1.81E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31610384	rs1077394	C	T	rs1077394	20598377	3.66E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31611777	rs760293	T	C	rs760293	17660530	9.72E-20	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31618761	rs3130050	G	A	rs3130050	20598377	1.33E-07	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31622606	rs805297	C	A	rs805297	17660530	5.46E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31778272	rs2227956	G	A	rs2227956	20598377	1.89E-07	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31824828	rs9267649	A	G	rs9267649	20598377	1.07E-07	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31837277	rs660550	C	A	rs660550	20598377	6.01E-07	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31838441	rs644827	T	C	rs644827	20598377	7.30E-07	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31839309	rs2242665	C	T	rs2242665	20598377	5.74E-07	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31845985	rs9267658	T	C	rs9267658	20598377	3.17E-08	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31856070	rs486416	G	A	rs486416	17660530	7.87E-17	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31860337	rs535586	T	C	rs535586	20598377	7.26E-07	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31864304	rs659445	G	A	rs659445	20598377	7.73E-07	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31883957	rs644045	A	G	rs644045	17660530	1.84E-16	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31893944	rs2734335	G	A	rs2734335	20598377	2.41E-06	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31919578	rs2072633	A	G	rs2072633	17660530	1.31E-14	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31922254	rs630379	A	C	rs630379	20598377	4.85E-07	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31929014	rs437179	A	C	rs437179	20598377	2.49E-07	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	31933161	rs406936	G	A	rs406936	19010793	5.37E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
6	31934372	rs454212	C	T	rs454212	19010793	5.37E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
6	31941557	rs387608	G	A	rs387608	19010793	4.57E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
6	31947460	rs389883	G	T	rs389883	20598377	1.83E-07	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32019769	rs12333245	G	A	rs12333245	19010793	4.37E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
6	32029183	rs2269429	C	T	rs2269429	19010793	3.16E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
6	32050544	rs3130287	C	T	rs3130287	17660530	2.26E-28	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32052983	rs169496	C	T	rs169496	19010793	3.89E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
6	32057627	rs204899	C	T	rs204899	19010793	5.13E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
6	32066177	rs17421624	T	C	rs17421624	17660530	2.51E-11	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32071893	rs3134954	C	T	rs3134954	20598377	3.19E-09	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32114515	rs9296009	A	T	rs9296009	17660530	1.85E-08	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32126002	rs3134603	A	G	rs3134603	20598377	8.36E-10	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32145707	rs2269423	A	C	rs2269423	20598377	8.14E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32147761	rs3134943	T	C	rs3134943	20598377	4.88E-10	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32180146	rs3131294	A	G	rs3131294	17660530	4.04E-32	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32186245	rs438475	G	A	rs438475	17660530	1.13E-09	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32189032	rs415929	T	C	rs415929	17660530	6.91E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32190028	rs3132946	A	G	rs3132946	20598377	6.73E-11	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32190620	rs3134931	T	C	rs3134931	20598377	4.68E-06	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32198867	rs404890	C	A	rs404890	20598377	3.69E-08	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32198936	rs2849015	G	A	rs2849015	20598377	5.58E-08	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32199352	rs9267873	C	T	rs9267873	20598377	2.32E-07	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32200147	rs3134926	C	G	rs3134926	17660530	1.16E-09	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32203537	rs3130299	A	G	rs3130299	20598377	5.39E-07	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32213052	rs9267954	A	T	rs9267954	17660530	9.16E-08	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32216850	rs3115576	T	A	rs3115576	17660530	2.29E-14	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32217092	rs6936204	T	C	rs6936204	17660530	2.98E-22	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32217185	rs9267971	T	C	rs9267971	17660530	6.12E-16	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32217367	rs3130311	A	G	rs3130311	17660530	5.76E-15	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32218843	rs3115573	A	G	rs3115573	20598377	5.17E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32220397	rs9267992	G	A	rs9267992	20598377	1.18E-14	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32220685	rs3130315	G	A	rs3130315	20598377	5.17E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32223258	rs3130320	T	C	rs3130320	20598377	4.22E-08	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32257566	rs926070	G	A	rs926070	20598377	1.13E-07	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32273158	rs544358	G	C	rs544358	17660530	2.18E-14	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32282033	rs547261	G	A	rs547261	20598377	6.05E-06	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32288190	rs574710	T	C	rs574710	17660530	6.03E-15	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32288462	rs539703	A	C	rs539703	17660530	2.14E-14	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32289318	rs547077	T	C	rs547077	20598377	1.08E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32297310	rs12524063	T	A	rs12524063	17660530	2.58E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32298372	rs9405090	A	G	rs9405090	20598377	3.40E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32305690	rs926591	C	A	rs926591	17660530	7.12E-15	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32305979	rs3129900	G	T	rs3129900	17660530	2.63E-37	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32306090	rs9368716	G	A	rs9368716	17660530	5.06E-16	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32307382	rs1033500	G	A	rs1033500	20598377	3.09E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32313097	rs4959093	T	C	rs4959093	17660530	8.11E-15	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32315654	rs910050	G	C	rs910050	17660530	9.99E-10	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32315727	rs910049	T	C	rs910049	17660530	1.97E-23	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32324817	rs9268302	C	T	rs9268302	17660530	1.05E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32324945	rs6907322	G	A	rs6907322	17660530	2.56E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32325835	rs2894249	C	T	rs2894249	17660530	3.49E-20	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32326045	rs2395150	G	A	rs2395150	20598377	1.40E-06	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32333955	rs9268368	T	C	rs9268368	20598377	3.40E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32336127	rs3129932	G	C	rs3129932	17660530	5.76E-28	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32336187	rs3129934	T	C	rs3129934	17660530	2.60E-40	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32336187	rs3129934	T	C	rs3129934	18941528	9.00E-11	NA	3.3	[2.30-4.90]	242 cases; 242 controls	NOPOP(484)	ALL(484)	NOPOP(484)	ALL(484)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32336187	rs3129934	T	C	rs3129934	22457343	7.00E-16	NA	2.34	[1.90-2.87]	197 European ancestry cases; 234 European ancestry controls	European(431)	ALL(431)	EUR(431)	ALL(431)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32336586	rs9268384	A	G	rs9268384	20598377	3.50E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32337686	rs3129941	A	G	rs3129941	20598377	4.00E-10	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32341353	rs9268402	G	A	rs9268402	17660530	9.92E-18	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32341398	rs9391858	A	G	rs9391858	17660530	8.38E-10	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32341473	rs9268403	T	C	rs9268403	17660530	2.91E-08	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32343686	rs9268418	T	C	rs9268418	17660530	7.04E-08	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32345052	rs9268429	A	G	rs9268429	17660530	9.73E-09	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32345086	rs12528797	A	G	rs12528797	17660530	4.28E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32358513	rs3117098	G	A	rs3117098	20598377	2.19E-07	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32363527	rs2076533	C	T	rs2076533	17660530	4.01E-13	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32363816	rs2076530	T	C	rs2076530	17660530	2.46E-13	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32363844	rs9268480	C	T	rs9268480	17660530	8.00E-08	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32368087	rs3817963	T	C	rs3817963	23472185	6.00E-10	NA	1.61	[1.38-1.87]	1,367 European ancestry OCB positive cases; 161 European ancestry OCB negative cases; 428 European ancestry controls	European(1956)	ALL(1956)	EUR(1956)	ALL(1956)	Multiple sclerosis (OCB status)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
6	32368087	rs3817963	T	C	rs3817963	23472185	8.00E-06	OCB positive vs. controls	1.52	[1.27-1.79]	1,367 European ancestry OCB positive cases; 161 European ancestry OCB negative cases; 428 European ancestry controls	European(1956)	ALL(1956)	EUR(1956)	ALL(1956)	Multiple sclerosis (OCB status)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
6	32373698	rs3806156	G	T	rs3806156	17660530	4.56E-09	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32374622	rs3763307	A	T	rs3763307	17660530	1.37E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32385399	rs3135377	A	G	rs3135377	17660530	6.32E-28	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32389305	rs9268557	T	C	rs9268557	17660530	7.37E-17	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32389512	rs9268560	C	G	rs9268560	17660530	1.83E-16	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32389648	rs3135363	A	G	rs3135363	20598377	8.62E-07	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32396615	rs3135342	G	T	rs3135342	17660530	2.48E-10	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32398675	rs7756262	T	A	rs7756262	17660530	1.42E-10	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32401217	rs3135338	C	T	rs3135338	20159113	2.00E-25	NA	3.43	NA	68 Finnish cases; 136 Finnish controls	Finnish(204)	ALL(204)	EUR(204)	ALL(204)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32401217	rs3135338	C	T	rs3135338	20598377	9.46E-10	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32404135	rs5000563	A	G	rs5000563	17660530	2.31E-10	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32404859	rs2395173	A	G	rs2395173	20598377	1.02E-09	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32406342	rs3129871	A	C	rs3129871	20598377	5.26E-08	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32406342	rs3129871	A	C	rs3129871	23472185	1.00E-16	OCB positive vs. controls	1.98	[1.68-2.32]	1,367 European ancestry OCB positive cases; 161 European ancestry OCB negative cases; 428 European ancestry controls	European(1956)	ALL(1956)	EUR(1956)	ALL(1956)	Multiple sclerosis (OCB status)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
6	32406342	rs3129871	A	C	rs3129871	23472185	6.00E-15	NA	1.72	[1.59-1.86]	1,367 European ancestry OCB positive cases; 161 European ancestry OCB negative cases; 428 European ancestry controls	European(1956)	ALL(1956)	EUR(1956)	ALL(1956)	Multiple sclerosis (OCB status)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
6	32407153	rs3129872	A	T	rs3129872	17660530	2.64E-10	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32408527	rs9268645	C	G	rs9268645	17660530	1.96E-11	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32408597	rs3129877	G	A	rs3129877	17660530	9.12E-11	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32409242	rs3135392	C	A	rs3135392	17660530	2.87E-13	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32409530	rs3129882	G	A	rs3129882	20598377	1.53E-07	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32411523	rs2239804	T	C	rs2239804	20598377	5.48E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32411646	rs7192	T	G	rs7192	20598377	2.14E-06	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32412435	rs3177928	G	A	rs3177928	17660530	2.24E-09	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32412480	rs7194	G	A	rs7194	17660530	6.01E-25	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32413051	rs3135388	A	G	rs3135388	17660530	9.00E-81	NA	1.99	[1.84-2.15]	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32413051	rs3135388	A	G	rs3135388	19525953	4.00E-225	NA	2.75	[2.46-3.07]	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32413317	rs2395182	G	T	rs2395182	20598377	9.03E-15	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32413545	rs3129889	G	A	rs3129889	22190364	1.00E-206	NA	2.97	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32427748	rs9268831	C	T	rs9268831	17660530	3.03E-13	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32427789	rs9268832	T	C	rs9268832	20598377	1.09E-07	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32428285	rs6903608	C	T	rs6903608	20598377	2.15E-07	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32429643	rs9268853	T	C	rs9268853	17660530	7.40E-10	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32429758	rs9268858	T	C	rs9268858	17660530	6.17E-09	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32431147	rs9268877	A	G	rs9268877	17660530	2.87E-16	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32520907	rs3828840	T	C	rs3828840	23472185	5.00E-15	OCB positive vs. controls	1.94	[1.64-2.29]	1,367 European ancestry OCB positive cases; 161 European ancestry OCB negative cases; 428 European ancestry controls	European(1956)	ALL(1956)	EUR(1956)	ALL(1956)	Multiple sclerosis (OCB status)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
6	32574060	rs9270986	A	C	rs9270986	17660530	2.38E-39	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32574171	rs615672	G	C	rs615672	17660530	7.54E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32586854	rs9271366	G	A	rs9271366	19525955	7.00E-184	NA	2.78	NA	1,618 European ancestry cases; 3,413 European ancestry controls	European(5031)	ALL(5031)	EUR(5031)	ALL(5031)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32586854	rs9271366	G	A	rs9271366	20598377	4.00E-17	NA	2.62	[2.09-3.28]	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32592200	rs9271640	T	C	rs9271640	23472185	2.00E-20	OCB positive vs. controls	2.37	[1.97-2.84]	1,367 European ancestry OCB positive cases; 161 European ancestry OCB negative cases; 428 European ancestry controls	European(1956)	ALL(1956)	EUR(1956)	ALL(1956)	Multiple sclerosis (OCB status)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
6	32595083	rs3129768	G	T	rs3129768	17660530	3.37E-35	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32599999	rs9272105	G	A	rs9272105	21502966	4.00E-10	NA	0.26	[NA] unit increase	178 European ancestry antibody-positive individuals; 178 European ancestry antibody-negative individuals	European(356)	ALL(356)	EUR(356)	ALL(356)	Response to interferon beta therapy	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
6	32603007	rs2040406	A	G	rs2040406	20453840	1.00E-20	NA	2.05	NA	882 Sardinian cases; 872 Sardinian controls	Sardinian(1754)	ALL(1754)	EUR(1754)	ALL(1754)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32604372	rs9272346	G	A	rs9272346	17660530	4.43E-13	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32658310	rs9469220	G	A	rs9469220	17660530	4.45E-18	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32658624	rs2157051	G	A	rs2157051	20598377	1.50E-07	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32663631	rs3129720	T	C	rs3129720	23472185	5.00E-15	OCB positive vs. controls	1.91	[1.62-2.24]	1,367 European ancestry OCB positive cases; 161 European ancestry OCB negative cases; 428 European ancestry controls	European(1956)	ALL(1956)	EUR(1956)	ALL(1956)	Multiple sclerosis (OCB status)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
6	32663851	rs6457617	C	T	rs6457617	17660530	9.47E-15	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32663999	rs6457620	G	C	rs6457620	17660530	3.41E-13	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32668336	rs2647046	A	C	rs2647046	17660530	1.04E-20	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32670244	rs9275418	A	G	rs9275418	17660530	6.35E-08	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32674994	rs9275523	C	A	rs9275523	17660530	9.69E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32677912	rs9275563	C	T	rs9275563	23472185	6.00E-11	OCB positive vs. controls	1.75	[1.47-2.04]	1,367 European ancestry OCB positive cases; 161 European ancestry OCB negative cases; 428 European ancestry controls	European(1956)	ALL(1956)	EUR(1956)	ALL(1956)	Multiple sclerosis (OCB status)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
6	32678999	rs9275572	A	G	rs9275572	17660530	1.74E-20	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32689324	rs9275765	A	T	rs9275765	17660530	3.30E-21	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32689503	rs9275772	T	C	rs9275772	17660530	7.53E-22	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32689529	rs9461799	T	C	rs9461799	17660530	3.86E-13	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32690001	rs9469240	C	T	rs9469240	17660530	7.16E-13	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32690027	rs9275793	G	A	rs9275793	17660530	3.13E-21	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32711782	rs2227127	A	G	rs2227127	17660530	7.47E-13	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32712104	rs9276429	G	A	rs9276429	17660530	5.39E-15	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32712247	rs9276431	T	C	rs9276431	17660530	3.40E-15	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32712384	rs9276432	T	C	rs9276432	17660530	4.28E-15	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32714783	rs9276440	A	T	rs9276440	17660530	6.34E-15	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32725193	rs2301271	A	G	rs2301271	20598377	7.67E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32729821	rs7768538	C	A	rs7768538	17660530	4.59E-15	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32730012	rs7453920	A	G	rs7453920	17660530	3.99E-15	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32730012	rs7453920	A	G	rs7453920	20598377	7.01E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32730086	rs2051549	G	A	rs2051549	17660530	7.98E-15	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32730086	rs2051549	G	A	rs2051549	20598377	8.70E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32731960	rs6902723	G	A	rs6902723	17660530	2.40E-14	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32732210	rs6903130	G	A	rs6903130	17660530	1.40E-13	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32736144	rs9296044	T	A	rs9296044	17660530	2.00E-12	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32740411	rs2857212	A	G	rs2857212	17660530	8.19E-09	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32741742	rs2857210	A	G	rs2857210	17660530	4.10E-14	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32759273	rs2621384	C	T	rs2621384	17660530	4.64E-14	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32759297	rs2857161	G	A	rs2857161	17660530	5.42E-20	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32759335	rs2621383	C	A	rs2621383	17660530	5.42E-20	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32760445	rs2621382	G	T	rs2621382	17660530	6.43E-15	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32760714	rs2157082	G	T	rs2157082	17660530	2.07E-15	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32762616	rs2857154	A	G	rs2857154	17660530	2.18E-15	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32775686	rs2857136	A	G	rs2857136	17660530	2.17E-14	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32776623	rs2857129	A	T	rs2857129	17660530	3.44E-14	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32800412	rs1800454	C	T	rs1800454	17660530	1.59E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32804414	rs241427	A	G	rs241427	17660530	4.34E-19	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32829714	rs9276825	G	A	rs9276825	17660530	1.34E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32866992	rs241403	T	C	rs241403	17660530	4.12E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32870057	rs3101942	G	A	rs3101942	17660530	4.39E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32903900	rs151719	C	T	rs151719	17660530	1.43E-16	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32917857	rs1050391	A	G	rs1050391	17660530	1.46E-11	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32917980	rs11539216	G	A	rs11539216	17660530	9.95E-11	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32938199	rs17840186	G	A	rs17840186	17660530	4.94E-10	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	32959180	rs3129305	G	C	rs3129305	17660530	1.70E-11	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	33018310	rs3130578	T	C	rs3130578	17660530	7.03E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	33018459	rs3130179	A	G	rs3130179	17660530	7.61E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	51359852	rs4715222	T	C	rs4715222	17660530	2.54E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	56552636	rs16888118	C	T	rs16888118	17660530	5.56E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	83041140	rs6454267	A	G	rs6454267	19010793	3.31E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
6	90127390	rs854917	C	T	rs854917	21833088	1.70E-04	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	90926612	rs10806425	C	A	rs10806425	22190364	3.89E-10	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	90958231	rs11755527	C	G	rs11755527	22190364	5.00E-12	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	90996769	rs12212193	A	G	rs12212193	21833088	4.00E-08	NA	1.09	[1.08-1.10]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	96083087	rs4388292	T	G	rs4388292	20598377	1.52E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	98019080	rs9320598	A	G	rs9320598	23785401	9.00E-07	NA	2.17	NA	49 European ancestry OCB negative cases; 513 European ancestry OCB positive cases	European(562)	ALL(562)	EUR(562)	ALL(562)	Multiple sclerosis (OCB status)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
6	105223864	rs733724	G	A	rs733724	23412934	3.00E-07	Cluxel size	NA	NA	284 European ancestry individuals	European(284)	ALL(284)	EUR(284)	ALL(284)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	105612220	rs11962089	A	G	rs11962089	21654844	8.00E-06	Continuous	0.69	[NA] unit decrease	1,470 European ancestry cases	European(1470)	ALL(1470)	EUR(1470)	ALL(1470)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	106435269	rs7746082	G	C	rs7746082	22190364	2.44E-10	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	106568034	rs548234	C	T	rs548234	22190364	4.50E-08	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	106588806	rs6568431	A	C	rs6568431	22190364	7.10E-10	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	108916573	rs9480865	T	C	rs9480865	19010793	7.00E-06	NA	NA	NA	753 European ancestry cases; 883 European ancestry controls	European(1636)	ALL(1636)	EUR(1636)	ALL(1636)	Normalized brain volume	HPOID:0002011	Abnormality of the central nervous system	DOID:2377	multiple sclerosis	D009103	Multiple Sclerosis	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
6	111549162	rs2297939	G	A	rs2297939	20598377	4.88E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	113972290	rs9387161	C	T	rs9387161	19010793	1.58E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
6	124771166	rs524235	C	T	rs524235	17660530	2.19E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	126698719	rs9388489	A	G	rs9388489	22190364	4.20E-13	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	128278798	rs802734	A	G	rs802734	21833088	6.00E-09	NA	1.1	[1.09-1.12]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	128278798	rs802734	A	G	rs802734	22190364	2.62E-14	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	130187499	rs9492408	T	G	rs9492408	19010793	9.55E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
6	135494875	rs9321490	T	C	rs9321490	21833088	2.00E-06	Conditioned on rs11154801	1.1	[1.08-1.11]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	135739355	rs11154801	C	A	rs11154801	21833088	1.00E-13	NA	1.13	[1.11-1.15]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	137452908	rs17066096	A	G	rs17066096	19525953	3.33E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	137452908	rs17066096	A	G	rs17066096	21833088	6.00E-13	NA	1.14	[1.12-1.15]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	137452908	rs17066096	A	G	rs17066096	24234648	9.60E-04	NA	1.13	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	137874408	rs9321619	A	G	rs9321619	19525953	1.71E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	137967214	rs13192841	G	A	rs13192841	21833088	1.00E-08	Conditioned on rs17066096	1.1	[1.09-1.12]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	137973068	rs2327832	A	G	rs2327832	22190364	4.46E-19	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	138002637	rs10499194	C	T	rs10499194	22190364	1.00E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	138006504	rs6920220	G	A	rs6920220	22190364	8.90E-13	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	138138705	rs892999	G	A	rs892999	19525953	3.12E-06	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	138195151	rs5029937	G	T	rs5029937	22190364	5.30E-13	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	138199417	rs610604	G	T	rs610604	22190364	9.00E-12	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	144041290	rs9376783	C	G	rs9376783	17660530	6.48E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	144041537	rs9403525	C	T	rs9403525	17660530	3.46E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	144041704	rs6915752	G	T	rs6915752	17660530	2.31E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	144042122	rs6570578	T	C	rs6570578	17660530	1.19E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	153802064	rs13208348	A	G	rs13208348	17660530	9.37E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	153808077	rs17250161	G	C	rs17250161	17660530	8.65E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	153829610	rs11756951	C	T	rs11756951	17660530	8.65E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	159465977	rs1738074	T	C	rs1738074	21833088	7.00E-15	NA	1.13	[1.12-1.15]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	159465977	rs1738074	T	C	rs1738074	22190364	4.00E-07	NA	1.15	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	159465977	rs1738074	T	C	rs1738074	24234648	7.50E-04	NA	1.12	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	159489791	rs212389	G	A	rs212389	22190364	2.70E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	160301358	rs6925813	T	C	rs6925813	19010793	7.94E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
6	160379096	rs12202350	T	C	rs12202350	19010793	1.95E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
6	160402705	rs6917747	G	A	rs6917747	19010793	7.00E-06	NA	NA	NA	791 European ancestry cases; 883 European ancestry controls	European(1674)	ALL(1674)	EUR(1674)	ALL(1674)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
6	166510789	rs3127390	G	A	rs3127390	19010793	8.91E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
6	167437988	rs2301436	C	T	rs2301436	22190364	1.04E-12	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
6	167534290	rs3093023	G	A	rs3093023	22190364	1.50E-11	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	2448493	rs6952809	T	C	rs6952809	21833088	4.00E-06	Conditioned on rs1843938	1.08	[1.06-1.09]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	3113034	rs1843938	G	A	rs1843938	21833088	1.10E-05	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	7268431	rs10259085	C	T	rs10259085	19010793	4.00E-06	NA	NA	NA	794 European ancestry cases; 883 European ancestry controls	European(1677)	ALL(1677)	EUR(1677)	ALL(1677)	Multiple sclerosis (severity)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
7	10796892	rs2214543	C	T	rs2214543	21833088	1.60E-04	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	12070537	rs2908734	T	C	rs2908734	20598377	7.62E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	12609988	rs2240571	G	C	rs2240571	21346779	5.18E-05	Multiple sclerosis	NA	NA	2793 European ancestry individuals	European(2793)	ALL(2793)	EUR(2793)	ALL(2793)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	13637369	rs17280766	A	G	rs17280766	19525953	1.63E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	18918559	rs7811991	T	C	rs7811991	20802204	1.24E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
7	22146840	rs7793103	A	G	rs7793103	20802204	1.28E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
7	22295360	rs2214935	A	G	rs2214935	19525953	2.93E-06	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	22768249	rs2066992	G	T	rs2066992	21833088	6.30E-05	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	26891665	rs7804356	T	C	rs7804356	22190364	5.30E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	28185891	rs849142	T	C	rs849142	22190364	1.50E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	29018593	rs504453	G	A	rs504453	20802204	4.00E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
7	29105096	rs2391720	T	C	rs2391720	17660530	3.67E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	29105465	rs550396	G	A	rs550396	17660530	5.94E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	29110857	rs17675986	A	T	rs17675986	17660530	7.01E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	29120445	rs17748997	C	T	rs17748997	17660530	8.04E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	36094620	rs9638917	G	T	rs9638917	19010793	8.51E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
7	36103289	rs1806468	C	T	rs1806468	19010793	7.41E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
7	37436854	rs11984075	A	G	rs11984075	21833088	1.10E-05	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	43009193	rs1427658	C	T	rs1427658	17660530	1.95E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	50269672	rs1456893	G	A	rs1456893	22190364	4.60E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	51027194	rs4948088	A	C	rs4948088	22190364	4.40E-08	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	55307580	rs12718948	G	A	rs12718948	19010793	9.77E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
7	70811708	rs16869429	G	A	rs16869429	20802204	3.20E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
7	75951230	rs7789940	A	G	rs7789940	21654844	6.00E-06	Extreme	1.87	NA	1,470 European ancestry cases	European(1470)	ALL(1470)	EUR(1470)	ALL(1470)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	75953297	rs758944	C	A	rs758944	21654844	8.00E-06	Continuous	0.48	[NA] unit increase	1,470 European ancestry cases	European(1470)	ALL(1470)	EUR(1470)	ALL(1470)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	75975586	rs7779014	C	T	rs7779014	21654844	8.00E-06	Continuous	0.48	[NA] unit increase	1,470 European ancestry cases	European(1470)	ALL(1470)	EUR(1470)	ALL(1470)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	75978229	rs17149161	C	A	rs17149161	21654844	6.00E-06	Extreme	1.87	NA	1,470 European ancestry cases	European(1470)	ALL(1470)	EUR(1470)	ALL(1470)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	80874222	rs1509913	C	T	rs1509913	17660530	8.03E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	83502255	rs6467970	A	G	rs6467970	17660530	1.97E-10	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	85002595	rs6944054	A	G	rs6944054	18195134	7.00E-04	Response to interferon beta therapy in multiple sclerosis (responders vs nonresponders)	NA	NA	206 Southern European multiple sclerosis cases	Southern European(206)	ALL(206)	EUR(206)	ALL(206)	Response to interferon beta in multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	85289738	rs4529380	G	A	rs4529380	17660530	2.19E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	98760504	rs7809799	G	A	rs7809799	22190364	9.00E-11	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	103619298	rs10487180	C	A	rs10487180	19010793	2.51E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
7	103619783	rs10244615	C	T	rs10244615	19010793	2.88E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
7	103628036	rs17157903	C	T	rs17157903	19010793	3.00E-06	NA	NA	NA	978 European ancestry cases; 883 European ancestry controls	European(1861)	ALL(1861)	EUR(1861)	ALL(1861)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
7	110391921	rs868824	T	C	rs868824	19010793	9.55E-06	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
7	110400223	rs17157942	C	T	rs17157942	19010793	7.08E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
7	110419154	rs1528041	C	T	rs1528041	19010793	6.46E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
7	110429536	rs1881164	C	T	rs1881164	19010793	2.82E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
7	110435602	rs1950004	T	C	rs1950004	19010793	4.47E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
7	110451383	rs7778910	C	A	rs7778910	19010793	2.04E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
7	116346603	rs10243024	G	A	rs10243024	19010793	6.00E-06	NA	NA	NA	794 European ancestry cases; 883 European ancestry controls	European(1677)	ALL(1677)	EUR(1677)	ALL(1677)	Multiple sclerosis (severity)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
7	128594183	rs10488631	T	C	rs10488631	22190364	4.20E-11	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	132869834	rs6942866	T	C	rs6942866	17660530	1.78E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	132873077	rs4389875	C	T	rs4389875	17660530	1.79E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	149289464	rs354033	G	A	rs354033	21833088	5.00E-09	NA	1.11	[1.10-1.13]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	149289464	rs354033	G	A	rs354033	24234648	7.90E-04	NA	1.13	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
7	150428109	rs11772925	C	T	rs11772925	19525953	8.01E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	877433	rs7822510	A	C	rs7822510	19010793	2.51E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
8	1883352	rs13279485	T	C	rs13279485	23412934	1.00E-06	Cluxel size	NA	NA	284 European ancestry individuals	European(284)	ALL(284)	EUR(284)	ALL(284)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	3128048	rs13272161	G	C	rs13272161	17660530	9.76E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	3828138	rs1529316	C	T	rs1529316	19010793	2.00E-06	NA	1.36	NA	978 European ancestry cases; 883 European ancestry controls	European(1861)	ALL(1861)	EUR(1861)	ALL(1861)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	4969414	rs11786333	G	A,C	rs11786333	20598377	5.15E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	5666765	rs4875628	A	G	rs4875628	19010793	3.24E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
8	9411808	rs9644677	G	A	rs9644677	19525955	5.10E-05	NA	NA	NA	1,618 European ancestry cases; 3,413 European ancestry controls	European(5031)	ALL(5031)	EUR(5031)	ALL(5031)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	9421789	rs6986386	C	T	rs6986386	21833088	1.60E-05	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	11343973	rs2736340	C	T	rs2736340	22190364	3.40E-12	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	15709114	rs2736070	T	G	rs2736070	20802204	3.68E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
8	32453358	rs3924999	G	A	rs3924999	20598377	3.16E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	32456511	rs10954863	G	A	rs10954863	20598377	4.50E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	33098541	rs11991723	C	G	rs11991723	17660530	7.95E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	33181409	rs4609155	T	C	rs4609155	17660530	9.60E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	33615617	rs4733171	G	C	rs4733171	17660530	1.74E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	37065784	rs1850650	G	A	rs1850650	19010793	4.47E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
8	61947573	rs1962862	T	C	rs1962862	20598377	5.90E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	70945599	rs6993479	A	G	rs6993479	19010793	4.68E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
8	73363183	rs348164	C	A	rs348164	19010793	1.29E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
8	73363989	rs2116078	T	G	rs2116078	19010793	3.00E-06	NA	NA	NA	978 European ancestry cases; 883 European ancestry controls	European(1861)	ALL(1861)	EUR(1861)	ALL(1861)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
8	74316068	rs4738350	G	A	rs4738350	17660530	3.90E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	79401038	rs1520333	A	G	rs1520333	21833088	2.00E-07	NA	1.1	[1.08-1.11]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	79501241	rs16905824	A	G	rs16905824	17660530	2.03E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	79532730	rs2369294	C	T	rs2369294	17660530	8.38E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	79654145	rs6993386	A	G	rs6993386	17660530	6.87E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	86104868	rs4150894	G	A	rs4150894	17660530	3.28E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	90819998	rs39767	A	G	rs39767	19525955	2.50E-05	NA	NA	NA	1,618 European ancestry cases; 3,413 European ancestry controls	European(5031)	ALL(5031)	EUR(5031)	ALL(5031)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	107913396	rs4615542	C	T	rs4615542	19010793	3.63E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
8	107916446	rs11992975	A	G	rs11992975	19010793	3.63E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
8	109086419	rs13256880	G	A	rs13256880	17660530	8.31E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	109779789	rs4735076	C	T	rs4735076	20802204	2.17E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
8	119391409	rs17749211	C	T	rs17749211	23412934	8.00E-06	Cluxel size	NA	NA	284 European ancestry individuals	European(284)	ALL(284)	EUR(284)	ALL(284)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	126540051	rs1551398	G	A	rs1551398	22190364	4.50E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	128815029	rs4410871	T	C	rs4410871	21833088	8.00E-09	NA	1.11	[1.09-1.12]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	129192271	rs2019960	T	C	rs2019960	21833088	5.00E-09	Conditioned on rs4410871	1.12	[1.10-1.13]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	129264589	rs9792269	A	G	rs9792269	22190364	3.28E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	131092413	rs6984045	T	C	rs6984045	19525955	2.00E-06	NA	1.59	NA	1,618 European ancestry cases; 3,413 European ancestry controls	European(5031)	ALL(5031)	EUR(5031)	ALL(5031)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	133989290	rs6998423	C	T	rs6998423	21833088	6.20E-06	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	136986018	rs2922350	T	C	rs2922350	17660530	2.14E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	137013447	rs1868368	T	C	rs1868368	17660530	8.52E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	140983203	rs2614724	A	G	rs2614724	17660530	3.59E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
8	142104944	rs4961252	A	G	rs4961252	21502966	3.00E-08	NA	0.23	[NA] unit increase	178 European ancestry antibody-positive individuals; 178 European ancestry antibody-negative individuals	European(356)	ALL(356)	EUR(356)	ALL(356)	Response to interferon beta therapy	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
9	557340	rs10975130	T	C	rs10975130	17660530	1.71E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	559714	rs2804262	C	A	rs2804262	17660530	7.13E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	571085	rs10975200	A	G	rs10975200	17660530	9.95E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	607901	rs9696204	G	C	rs9696204	17660530	8.41E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	2492466	rs4741717	G	A	rs4741717	17660530	5.55E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	4291747	rs7020673	C	G	rs7020673	22190364	5.40E-12	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	4760538	rs10815070	G	C	rs10815070	17660530	6.13E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	4981602	rs10758669	C	A	rs10758669	22190364	3.46E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	5893861	rs2150702	G	A,T	rs2150702	22190364	3.00E-08	NA	1.16	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	5893861	rs2150702	G	A,T	rs2150702	24234648	2.50E-05	NA	1.14	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	7164502	rs1556099	C	A	rs1556099	19010793	7.76E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
9	7757891	rs7863770	C	T	rs7863770	20802204	3.57E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
9	14547633	rs12002454	T	C	rs12002454	20802204	3.41E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
9	17938351	rs1755289	T	C	rs1755289	19010793	3.00E-06	NA	1.35	NA	978 European ancestry cases; 883 European ancestry controls	European(1861)	ALL(1861)	EUR(1861)	ALL(1861)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	21064876	rs1857652	C	T	rs1857652	17660530	8.98E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	24650899	rs10812071	C	A,G,T	rs10812071	19010793	8.51E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
9	28111873	rs17771324	T	C	rs17771324	19010793	9.77E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
9	34743681	rs951005	G	A	rs951005	22190364	3.90E-10	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	35992302	rs1408466	T	C	rs1408466	19010793	9.33E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
9	78902949	rs2260411	T	C	rs2260411	19010793	1.29E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
9	78903526	rs2842488	A	G	rs2842488	19010793	1.58E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
9	78904508	rs903547	C	A	rs903547	19010793	1.20E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
9	78906150	rs2842483	A	G	rs2842483	19010793	5.00E-06	NA	NA	NA	978 European ancestry cases; 883 European ancestry controls	European(1861)	ALL(1861)	EUR(1861)	ALL(1861)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
9	78909274	rs2803418	G	T	rs2803418	19010793	8.32E-06	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
9	81169950	rs2047995	T	C	rs2047995	17660530	8.71E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	81310680	rs1757948	A	C	rs1757948	21833088	3.00E-06	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	81313820	rs1634352	A	G	rs1634352	21833088	8.00E-06	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	89314179	rs1029046	C	T	rs1029046	20598377	8.01E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	93475945	rs1172902	A	G	rs1172902	18195134	2.00E-04	Response to interferon beta therapy in multiple sclerosis (responders vs nonresponders)	NA	NA	206 Southern European multiple sclerosis cases	Southern European(206)	ALL(206)	EUR(206)	ALL(206)	Response to interferon beta in multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	93563536	rs290986	A	G	rs290986	21833088	9.00E-07	NA	1.1	[1.08-1.12]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	98840796	rs4562454	T	C	rs4562454	17660530	6.34E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	108166606	rs2812314	G	T	rs2812314	20598377	4.08E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	116967263	rs2567719	T	G	rs2567719	19525955	2.60E-05	NA	NA	NA	1,618 European ancestry cases; 3,413 European ancestry controls	European(5031)	ALL(5031)	EUR(5031)	ALL(5031)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	117566440	rs4263839	A	G	rs4263839	22190364	2.60E-10	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	121984553	rs10984447	A	G	rs10984447	17660530	8.00E-06		1.17	[1.09-1.25]	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	123690239	rs3761847	G	A	rs3761847	22190364	4.00E-14	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
9	126458540	rs10818858	C	T	rs10818858	20802204	2.99E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
9	136835343	rs3780792	A	G	rs3780792	20598377	1.00E-06	NA	1.6	[1.32-1.92]	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	6087794	rs11256497	G	A	rs11256497	19525953	1.33E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	6088699	rs791587	A	G	rs791587	17660530	3.03E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	6098949	rs706778	C	T	rs706778	22190364	1.40E-11	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	6099045	rs2104286	T	C	rs2104286	17660530	2.16E-07	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	6099045	rs2104286	T	C	rs2104286	19525953	9.00E-08	NA	1.15	[1.04-1.27]	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	6099045	rs2104286	T	C	rs2104286	19525955	7.00E-06	NA	1.16	NA	1,618 European ancestry cases; 3,413 European ancestry controls	European(5031)	ALL(5031)	EUR(5031)	ALL(5031)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	6099045	rs2104286	T	C	rs2104286	21833088	1.90E-05	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	6099045	rs2104286	T	C	rs2104286	22190364	3.52E-10	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	6101713	rs3118470	T	C	rs3118470	21833088	3.00E-11	NA	1.12	[1.10-1.13]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	6101713	rs3118470	T	C	rs3118470	24234648	7.80E-04	NA	1.12	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	6102012	rs12722489	C	T	rs12722489	17660530	3.00E-08		1.25	[1.11-1.36]	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	6102012	rs12722489	C	T	rs12722489	22190364	4.00E-08	NA	1.23	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	6110326	rs7089861	C	G	rs7089861	19525953	3.38E-07	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	6110326	rs7089861	C	G	rs7089861	22190364	4.34E-04	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	6110829	rs7090512	C	T	rs7090512	21833088	5.00E-20	Conditioned on rs3118470	1.19	[1.17-1.21]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	6390450	rs947474	G	A	rs947474	22190364	4.00E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	6393260	rs4750316	C	G	rs4750316	22190364	1.30E-08	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	13099342	rs637440	A	G	rs637440	17660530	2.29E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	13103202	rs11258164	A	G	rs11258164	17660530	9.42E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	26814452	rs702988	T	C	rs702988	20802204	1.76E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
10	30008663	rs1927457	T	C	rs1927457	19010793	8.00E-06	NA	NA	NA	753 European ancestry cases; 883 European ancestry controls	European(1636)	ALL(1636)	EUR(1636)	ALL(1636)	Normalized brain volume	HPOID:0002011	Abnormality of the central nervous system	DOID:2377	multiple sclerosis	D009103	Multiple Sclerosis	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
10	31415106	rs793108	C	T	rs793108	21833088	3.00E-06	NA	1.08	[1.06-1.09]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	35287650	rs17582416	T	G	rs17582416	22190364	1.79E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	43814049	rs2503875	G	A	rs2503875	20598377	2.00E-07	NA	1.66	[1.37-2.00]	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	43814896	rs2503876	A	G	rs2503876	20598377	4.02E-06	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	54158576	rs1733706	A	G	rs1733706	19010793	4.47E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
10	55199970	rs435882	T	G	rs435882	20802204	3.61E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
10	59305355	rs2393369	A	G	rs2393369	20802204	2.90E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
10	64438486	rs10995271	G	C	rs10995271	22190364	4.46E-20	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	67193137	rs10822550	G	A	rs10822550	19525953	1.71E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	69264597	rs10823051	G	C	rs10823051	17660530	2.38E-08	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	69373374	rs7097855	C	T	rs7097855	19010793	8.71E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
10	69405242	rs3125316	C	T	rs3125316	19010793	1.51E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
10	73046177	rs10823717	G	T	rs10823717	17660530	9.91E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	78727604	rs7912269	T	C	rs7912269	21833088	1.40E-05	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	79354471	rs2670117	A	G	rs2670117	17660530	9.61E-08	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	81034670	rs1250542	G	A	rs1250542	22190364	4.00E-07	NA	1.15	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	81036007	rs1250540	A	G	rs1250540	19525953	2.00E-06	NA	1.12	[1.02-1.22]	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	81036007	rs1250540	A	G	rs1250540	21833088	3.90E-04	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	81058027	rs1250552	A	G	rs1250552	22190364	9.09E-10	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	81060317	rs1250550	C	A	rs1250550	21833088	6.00E-09	NA	1.1	[1.09-1.12]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	81060317	rs1250550	C	A	rs1250550	22190364	6.00E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	90023033	rs10509540	T	C	rs10509540	22190364	1.30E-28	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	94481917	rs7923837	G	A	rs7923837	21833088	5.00E-09	NA	1.1	[1.08-1.11]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	101291593	rs11190140	T	C	rs11190140	22190364	3.06E-16	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	112006486	rs716595	G	A	rs716595	19010793	8.00E-06	NA	NA	NA	753 European ancestry cases; 883 European ancestry controls	European(1636)	ALL(1636)	EUR(1636)	ALL(1636)	Normalized brain volume	HPOID:0002011	Abnormality of the central nervous system	DOID:2377	multiple sclerosis	D009103	Multiple Sclerosis	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
10	113449034	rs11195680	T	C	rs11195680	20598377	6.06E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	114388272	rs17267338	A	G	rs17267338	23412934	8.00E-06	Cluxel size	NA	NA	284 European ancestry individuals	European(284)	ALL(284)	EUR(284)	ALL(284)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	116168638	rs11196730	G	A	rs11196730	19010793	6.17E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
10	116183068	rs7075375	A	G	rs7075375	19010793	3.24E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
10	119180751	rs730080	C	T	rs730080	19010793	3.31E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
10	122088912	rs7068990	G	A	rs7068990	17660530	1.92E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
10	129628500	rs7069806	T	C	rs7069806	17660530	4.03E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	589564	rs4963128	T	C	rs4963128	22190364	4.90E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	2170143	rs1004446	G	A	rs1004446	22190364	4.00E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	3259809	rs11026091	G	A	rs11026091	23412934	2.00E-06	Cluxel minimum distance	NA	NA	284 European ancestry individuals	European(284)	ALL(284)	EUR(284)	ALL(284)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	15648135	rs10500817	T	C	rs10500817	17660530	3.61E-09	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	33812828	rs12576094	C	T	rs12576094	20802204	1.44E-06	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
11	33814061	rs1000677	A	G	rs1000677	20802204	1.27E-06	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
11	40414427	rs1002254	C	A	rs1002254	17660530	3.04E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	43514710	rs12224013	T	G	rs12224013	19010793	8.71E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
11	60760612	rs17824933	C	A,G	rs17824933	19525953	4.00E-09	NA	1.18	[1.07-1.30]	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	60760612	rs17824933	C	A,G	rs17824933	21833088	5.50E-07	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	60793651	rs4939490	C	G	rs4939490	21244703	1.00E-09	NA	1.3	[1.19-1.42]	2,124 cases; 6,720 controls	NOPOP(8844)	ALL(8844)	NOPOP(8844)	ALL(8844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	60832282	rs650258	T	C	rs650258	21833088	2.00E-11	NA	1.12	[1.10-1.13]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	60832282	rs650258	T	C	rs650258	24234648	1.80E-04	NA	1.14	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	62001414	rs12806663	C	A,T	rs12806663	19010793	3.31E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
11	64097233	rs694739	A	G	rs694739	21833088	1.40E-04	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	71089210	rs1620013	C	T	rs1620013	17660530	1.84E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	76301316	rs7927894	C	T	rs7927894	22190364	1.32E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	78939166	rs616214	C	T	rs616214	17660530	8.12E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	87819427	rs1386330	T	C	rs1386330	19010793	2.00E-06	NA	NA	NA	978 European ancestry cases; 883 European ancestry controls	European(1861)	ALL(1861)	EUR(1861)	ALL(1861)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
11	90556357	rs2511317	C	T	rs2511317	19010793	3.80E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
11	95311422	rs4409785	T	C	rs4409785	21833088	6.00E-07	NA	1.1	[1.09-1.12]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	102628052	rs7924357	G	A	rs7924357	23412934	1.00E-06	Cluxel size	NA	NA	284 European ancestry individuals	European(284)	ALL(284)	EUR(284)	ALL(284)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	109176817	rs655763	C	T	rs655763	19525953	4.91E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	116238034	rs491111	G	A	rs491111	21833088	4.80E-04	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	116526322	rs486394	A	C	rs486394	17660530	2.19E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	116599392	rs180358	C	T	rs180358	19010793	6.00E-06	NA	NA	NA	794 European ancestry cases; 883 European ancestry controls	European(1677)	ALL(1677)	EUR(1677)	ALL(1677)	Multiple sclerosis (severity)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
11	117593119	rs11216515	T	C	rs11216515	17660530	8.02E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	118754353	rs630923	C	A	rs630923	21833088	3.00E-07	NA	1.12	[1.10-1.14]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	119976805	rs4938780	T	C	rs4938780	17660530	4.07E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	120161641	rs6589804	G	A	rs6589804	17660530	8.07E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	120167057	rs4142654	A	G	rs4142654	17660530	5.14E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	120273301	rs4373935	A	G	rs4373935	17660530	4.30E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	120614787	rs3133224	C	T	rs3133224	19010793	7.94E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
11	122462813	rs7103823	C	T	rs7103823	19010793	6.03E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
11	122522375	rs7941030	T	C	rs7941030	21833088	1.60E-05	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	128380974	rs11221332	C	T	rs11221332	22190364	5.28E-16	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
11	128434157	rs2156696	G	A	rs2156696	19010793	9.77E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
11	128435103	rs1944850	A	G	rs1944850	19010793	4.47E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
12	5784874	rs2215738	C	T	rs2215738	19010793	6.03E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
12	6440009	rs1800693	T	C	rs1800693	19525953	2.00E-11	NA	1.2	[1.10-1.31]	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	6440009	rs1800693	T	C	rs1800693	21833088	4.00E-14	NA	1.12	[1.11-1.14]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	6440009	rs1800693	T	C	rs1800693	22190364	7.92E-05	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	6442643	rs4149584	C	A,G,T	rs4149584	19525953	5.00E-06	NA	1.58	[1.15-2.17]	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	6449115	rs4149576	C	T	rs4149576	19525953	1.03E-08	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	9020328	rs7311897	T	C	rs7311897	19525953	5.67E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	9102412	rs1805755	A	G	rs1805755	17660530	4.89E-14	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	9735686	rs10771901	C	T	rs10771901	17660530	8.30E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	9755578	rs4763655	G	A	rs4763655	17660530	6.85E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	9876091	rs10466829	G	A	rs10466829	21833088	1.00E-08	NA	1.09	[1.08-1.11]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	9876091	rs10466829	G	A	rs10466829	24234648	9.00E-04	NA	1.11	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	9910164	rs4763879	G	A	rs4763879	22190364	1.90E-11	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	10418405	rs11053720	A	G	rs11053720	17660530	6.07E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	10507378	rs4764422	T	C	rs4764422	17660530	7.44E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	12016183	rs928936	G	T	rs928936	20802204	9.85E-06	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
12	16641512	rs6488848	G	C	rs6488848	17660530	2.02E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	18114417	rs2417686	T	C	rs2417686	19010793	8.13E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
12	25182403	rs10771158	G	A	rs10771158	19010793	3.39E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
12	25184008	rs1012980	A	G	rs1012980	19010793	6.03E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
12	32476727	rs261902	A	G	rs261902	19010793	4.00E-06	NA	NA	NA	753 European ancestry cases; 883 European ancestry controls	European(1636)	ALL(1636)	EUR(1636)	ALL(1636)	Normalized brain volume	HPOID:0002011	Abnormality of the central nervous system	DOID:2377	multiple sclerosis	D009103	Multiple Sclerosis	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
12	40601940	rs11175593	C	T	rs11175593	22190364	3.08E-10	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	40608880	rs10878220	C	T	rs10878220	19010793	7.24E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
12	41965861	rs1458175	A	C	rs1458175	19010793	2.00E-06	NA	1.34	NA	978 European ancestry cases; 883 European ancestry controls	European(1861)	ALL(1861)	EUR(1861)	ALL(1861)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	56482180	rs2292239	T	G	rs2292239	22190364	2.00E-20	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	56737973	rs2066808	A	G	rs2066808	22190364	1.00E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	58064737	rs10876994	A	C	rs10876994	19525955	2.70E-10	NA	NA	NA	1,618 European ancestry cases; 3,413 European ancestry controls	European(5031)	ALL(5031)	EUR(5031)	ALL(5031)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	58133256	rs12368653	G	A	rs12368653	19525955	1.00E-07	NA	NA	NA	1,618 European ancestry cases; 3,413 European ancestry controls	European(5031)	ALL(5031)	EUR(5031)	ALL(5031)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	58133256	rs12368653	G	A	rs12368653	21833088	2.00E-09	Conditioned on rs7238078	1.1	[1.09-1.12]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	58162739	rs703842	A	G	rs703842	19525955	5.00E-11	NA	1.23	NA	1,618 European ancestry cases; 3,413 European ancestry controls	European(5031)	ALL(5031)	EUR(5031)	ALL(5031)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	58162739	rs703842	A	G	rs703842	21833088	6.00E-06	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	58162739	rs703842	A	G	rs703842	22190364	1.72E-05	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	68504592	rs1558744	G	A	rs1558744	22190364	4.20E-12	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	77680091	rs10506738	T	G	rs10506738	18195134	2.00E-04	Response to interferon beta therapy in multiple sclerosis (responders vs nonresponders)	NA	NA	206 Southern European multiple sclerosis cases	Southern European(206)	ALL(206)	EUR(206)	ALL(206)	Response to interferon beta in multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	85025936	rs7960353	G	A	rs7960353	17660530	9.05E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	86239884	rs7137596	C	G	rs7137596	17660530	6.38E-08	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	89162115	rs10732643	T	G	rs10732643	19010793	6.61E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
12	95292948	rs7304048	T	C	rs7304048	19010793	1.74E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
12	112007756	rs653178	C	T	rs653178	22190364	7.15E-21	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	112486818	rs17696736	A	G	rs17696736	22190364	2.00E-16	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	115688402	rs10507257	A	G	rs10507257	20598377	3.63E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	118228441	rs4767621	G	A	rs4767621	17660530	4.28E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	120894685	rs7137953	C	T	rs7137953	19525953	2.19E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	123595163	rs949143	G	A	rs949143	21833088	5.80E-04	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	123626982	rs1106240	C	T	rs1106240	17660530	2.69E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	123632276	rs1569068	G	A	rs1569068	17660530	8.53E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	123638930	rs1727315	G	A	rs1727315	17660530	9.41E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	123640853	rs1727313	C	G	rs1727313	17660530	5.78E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	123651162	rs1716167	A	G	rs1716167	17660530	1.88E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	123651966	rs1716168	G	C	rs1716168	17660530	1.11E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	123656725	rs1790100	G	T	rs1790100	19525953	7.00E-07	NA	1.11	[1.00-1.22]	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	123656725	rs1790100	G	T	rs1790100	22190364	6.61E-04	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	123657338	rs2049114	T	C	rs2049114	19525953	1.15E-06	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	123689521	rs2695478	C	T	rs2695478	17660530	6.82E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	125625603	rs10773145	T	C	rs10773145	17660530	4.86E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	125674742	rs4412800	T	C	rs4412800	17660530	1.09E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
12	125681761	rs12578774	C	T	rs12578774	17660530	8.05E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
13	19895384	rs1330730	G	A	rs1330730	17660530	3.08E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
13	19906655	rs2812746	C	T	rs2812746	17660530	7.89E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
13	20912527	rs9550637	A	G	rs9550637	21833088	5.90E-06	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
13	39200826	rs11841753	C	T	rs11841753	17660530	6.54E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
13	42139245	rs17594362	C	T	rs17594362	21833088	4.00E-06	NA	1.11	[1.09-1.13]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
13	44457925	rs3764147	A	G	rs3764147	22190364	2.08E-13	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
13	44844238	rs6561169	C	T	rs6561169	19010793	2.09E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
13	48132734	rs12877713	T	C	rs12877713	17660530	2.78E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
13	50185204	rs9568281	A	G	rs9568281	23412934	3.00E-07	Cluxel size	NA	NA	284 European ancestry individuals	European(284)	ALL(284)	EUR(284)	ALL(284)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
13	50841323	rs806321	C	T	rs806321	21833088	5.00E-07	NA	1.08	[1.07-1.10]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
13	50842440	rs9596270	T	C	rs9596270	19525953	5.06E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
13	50842440	rs9596270	T	C	rs9596270	22190364	7.00E-07	NA	1.35	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
13	75982581	rs9530434	C	T	rs9530434	20802204	1.44E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
13	78813972	rs17745309	G	A	rs17745309	19010793	7.94E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
13	79467539	rs914936	T	A	rs914936	17660530	1.47E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
13	92902903	rs9301789	T	C	rs9301789	18195134	1.00E-04	Response to interferon beta therapy in multiple sclerosis (responders vs nonresponders)	NA	NA	206 Southern European multiple sclerosis cases	Southern European(206)	ALL(206)	EUR(206)	ALL(206)	Response to interferon beta in multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
13	93331886	rs9523762	G	A	rs9523762	19010793	1.00E-06	NA	1.36	NA	978 European ancestry cases; 883 European ancestry controls	European(1861)	ALL(1861)	EUR(1861)	ALL(1861)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
13	97205718	rs3899870	G	C	rs3899870	17660530	1.21E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
13	97205830	rs3899871	G	A	rs3899871	17660530	1.74E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
13	97206214	rs7334107	C	T	rs7334107	17660530	4.52E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
13	103296243	rs680840	A	G	rs680840	19010793	7.08E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
13	103306987	rs689358	C	T	rs689358	19010793	7.08E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
13	103315210	rs677594	G	A	rs677594	19010793	7.08E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
13	103326950	rs674929	G	A	rs674929	19010793	6.03E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
13	103333089	rs639862	G	T	rs639862	19010793	7.08E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
14	26851982	rs1956494	G	A	rs1956494	20802204	2.73E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
14	29021928	rs7493138	C	T	rs7493138	17660530	4.22E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
14	29249349	rs2038256	T	G	rs2038256	20802204	2.00E-06	NA	NA	NA	382 cases	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
14	32353250	rs2039485	T	C	rs2039485	19010793	6.00E-06	NA	NA	NA	791 European ancestry cases; 883 European ancestry controls	European(1674)	ALL(1674)	EUR(1674)	ALL(1674)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
14	51196142	rs2984274	T	C	rs2984274	19010793	4.27E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
14	52325131	rs4468527	A	G	rs4468527	19525953	9.97E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
14	54339493	rs7160860	T	C	rs7160860	17660530	2.69E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
14	66262963	rs8007846	A	G	rs8007846	20802204	9.00E-06	NA	NA	NA	382 cases	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
14	69254191	rs4902647	C	T	rs4902647	21833088	9.00E-12	NA	1.11	[1.10-1.13]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
14	69254191	rs4902647	C	T	rs4902647	24234648	2.20E-04	NA	1.12	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
14	69263599	rs1465788	T	C	rs1465788	22190364	1.80E-12	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
14	74912830	rs1125221	G	A	rs1125221	21833088	7.10E-06	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
14	76005557	rs2300603	T	C	rs2300603	21833088	2.00E-08	NA	1.11	[1.09-1.12]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
14	88487689	rs2119704	C	A	rs2119704	21833088	2.00E-10	NA	1.22	[1.19-1.25]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
14	94861516	rs11629242	A	G	rs11629242	19010793	9.77E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
14	94862149	rs8008466	T	C	rs8008466	19010793	1.10E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
14	98498951	rs4900384	A	G	rs4900384	22190364	3.70E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
15	22949828	rs1579821	A	G	rs1579821	20598377	2.19E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
15	38944052	rs8031623	G	A	rs8031623	20598377	8.57E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
15	50264532	rs12593937	T	C	rs12593937	19010793	9.12E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
15	50717068	rs7174015	G	A	rs7174015	17660530	9.38E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
15	55788832	rs16976351	C	T	rs16976351	19010793	5.50E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
15	58327347	rs2899611	T	G	rs2899611	20802204	2.26E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
15	79235446	rs3825932	T	C	rs3825932	22190364	3.00E-15	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
15	83852620	rs17841157	C	T	rs17841157	17660530	5.16E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
15	87241211	rs11631489	A	G	rs11631489	19010793	7.76E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
15	93124949	rs11074079	A	G	rs11074079	17660530	7.76E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
15	94907062	rs7171661	T	C	rs7171661	20598377	1.79E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
15	97921075	rs9788634	T	C	rs9788634	19010793	3.09E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
15	99112003	rs1319873	T	C	rs1319873	20802204	1.05E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
15	99950772	rs4393551	T	C	rs4393551	19010793	2.40E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
15	101546195	rs7163635	T	C	rs7163635	17660530	9.67E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	1073552	rs2744148	A	G	rs2744148	21833088	8.00E-08	NA	1.12	[1.10-1.14]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	6653568	rs733410	C	T	rs733410	17660530	3.53E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	11165017	rs11860603	T	C	rs11860603	19525953	3.04E-07	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	11166688	rs11865121	C	A	rs11865121	19525953	2.00E-07	NA	1.15	[1.04-1.25]	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	11174652	rs2041670	G	A	rs2041670	20598377	8.90E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	11177801	rs7200786	A	G	rs7200786	21833088	9.00E-17	NA	1.15	[1.13-1.16]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	11177801	rs7200786	A	G	rs7200786	24234648	8.80E-05	NA	1.14	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	11179873	rs12708716	A	G	rs12708716	19525953	1.49E-06	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	11179873	rs12708716	A	G	rs12708716	21833088	1.10E-12	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	11179873	rs12708716	A	G	rs12708716	22190364	1.08E-04	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	11227914	rs7184083	A	G	rs7184083	19525953	5.94E-07	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	11249329	rs6498169	G	A	rs6498169	17660530	4.00E-06	NA	1.14	[1.08-1.21]	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	11362729	rs11640138	G	A	rs11640138	19525953	3.41E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	11403893	rs12928822	C	T	rs12928822	22190364	3.12E-08	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	11406803	rs7191700	C	T	rs7191700	22190364	6.00E-07	NA	1.15	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	11475576	rs11864333	A	G	rs11864333	21833088	3.60E-05	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	23067260	rs8049603	T	G	rs8049603	19525955	1.00E-06	NA	1.19	NA	1,618 European ancestry cases; 3,413 European ancestry controls	European(5031)	ALL(5031)	EUR(5031)	ALL(5031)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	24974426	rs1035946	G	A	rs1035946	19525953	6.43E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	27391788	rs6498016	G	A	rs6498016	20802204	1.94E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
16	28539848	rs4788084	C	T	rs4788084	22190364	2.60E-13	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	28837515	rs8049439	T	C	rs8049439	22190364	2.00E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	31326706	rs11860650	C	T	rs11860650	22190364	1.90E-20	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	65137094	rs12232421	G	A	rs12232421	17660530	1.53E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	65223036	rs10500510	T	G	rs10500510	17660530	1.41E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	65983447	rs17765606	A	G	rs17765606	19525953	9.35E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	68591230	rs1728785	A	C	rs1728785	22190364	3.00E-08	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	69495181	rs4783708	C	T	rs4783708	17660530	5.67E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	69745145	rs1800566	G	A	rs1800566	19010793	9.55E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
16	73581058	rs7191888	A	G	rs7191888	19010793	6.00E-06	NA	NA	NA	794 European ancestry cases; 883 European ancestry controls	European(1677)	ALL(1677)	EUR(1677)	ALL(1677)	Multiple sclerosis (severity)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
16	75247245	rs7202877	T	G	rs7202877	22190364	3.10E-15	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	79586741	rs12598123	T	C	rs12598123	17660530	5.37E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	79652541	rs386965	C	T	rs386965	21833088	4.00E-06	NA	1.09	[1.07-1.11]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	82113471	rs2042429	C	T	rs2042429	20802204	2.37E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
16	84169624	rs9932838	C	T	rs9932838	20802204	9.55E-06	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
16	86011033	rs13333054	C	T	rs13333054	21833088	1.00E-08	NA	1.11	[1.10-1.13]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	86013551	rs1401884	G	C	rs1401884	19525953	6.83E-07	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	86017663	rs17445836	G	A	rs17445836	19525953	4.00E-09	NA	1.25	[1.12-1.39]	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	86017663	rs17445836	G	A	rs17445836	21833088	2.40E-06	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
16	86746818	rs9924445	A	G	rs9924445	19525953	2.46E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	831109	rs11247565	C	T	rs11247565	20598377	1.31E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	3396397	rs2035939	T	C	rs2035939	19010793	8.32E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
17	9384095	rs4791841	T	C	rs4791841	19010793	3.24E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
17	31318547	rs34889454	TA	T	rs16967819	17660530	2.36E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	31318547	rs5820007	T	C	rs16967819	17660530	2.36E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	31318829	rs4999077	C	T	rs4999077	17660530	7.98E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	38040763	rs2872507	G	A	rs2872507	22190364	5.00E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	38062196	rs2305480	G	A	rs2305480	22190364	3.00E-08	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	38066240	rs2290400	T	C	rs2290400	22190364	5.50E-13	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	38770286	rs7221109	T	C	rs7221109	22190364	1.30E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	40481529	rs2293152	G	C	rs2293152	22190364	4.00E-08	NA	1.22	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	40507980	rs9891119	A	C	rs9891119	21833088	2.00E-10	NA	1.11	[1.09-1.12]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	40507980	rs9891119	A	C	rs9891119	24234648	1.60E-04	NA	1.13	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	40514201	rs744166	A	G	rs744166	20159113	3.00E-10	NA	1.15	[1.10-1.20]	68 Finnish cases; 136 Finnish controls	Finnish(204)	ALL(204)	EUR(204)	ALL(204)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	40514201	rs744166	A	G	rs744166	21833088	1.20E-06	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	40514201	rs744166	A	G	rs744166	22190364	6.14E-05	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	43081974	rs11652163	A	G	rs11652163	19010793	9.55E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
17	43111688	rs9900173	G	A	rs9900173	19010793	3.39E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
17	43116313	rs9898793	C	T	rs9898793	19010793	3.55E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
17	43163851	rs6503422	T	C	rs6503422	19010793	8.13E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
17	43403005	rs4792814	T	C	rs4792814	21833088	3.00E-06	NA	1.08	[1.06-1.09]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	44915265	rs1373089	G	A	rs1373089	21833088	4.00E-05	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	45575206	rs9901869	G	A	rs9901869	19525953	8.72E-06	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	45575206	rs9901869	G	A	rs9901869	22190364	9.62E-07	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	45755810	rs4239162	G	A	rs4239162	19525953	6.93E-06	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	45768836	rs8070463	T	C	rs8070463	22190364	1.00E-07	NA	1.15	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	56010960	rs8074980	G	A	rs8074980	20802204	2.00E-06	NA	NA	NA	382 cases	NOPOP(382)	ALL(382)	NOPOP(382)	ALL(382)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
17	58024275	rs180515	A	G	rs180515	21833088	9.00E-08	NA	1.09	[1.08-1.11]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	66661438	rs11657722	A	G	rs11657722	20802204	3.38E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
17	72053767	rs2219402	C	T	rs2219402	17660530	9.80E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	72248947	rs8081928	G	C	rs8081928	17660530	1.67E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
17	72463021	rs2670827	C	T	rs2670827	20802204	2.38E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
17	76923426	rs4789933	C	T	rs4789933	19010793	8.71E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
17	78283987	rs8081176	T	C	rs8081176	21833088	1.50E-05	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
18	894965	rs4797328	C	T	rs4797328	17660530	1.93E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
18	9522606	rs329007	G	A	rs329007	19010793	8.71E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
18	12779947	rs2542151	G	T	rs2542151	22190364	5.10E-17	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
18	12809340	rs1893217	A	G	rs1893217	22190364	2.52E-10	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
18	28789725	rs2920001	T	C	rs2920001	23412934	1.00E-06	Cluxel minimum distance	NA	NA	284 European ancestry individuals	European(284)	ALL(284)	EUR(284)	ALL(284)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
18	41113801	rs1527436	T	G	rs1527436	19010793	9.33E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
18	54714164	rs11661212	C	T	rs11661212	19010793	2.19E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
18	54752314	rs1557351	T	C	rs1557351	19010793	4.00E-06	NA	NA	NA	978 European ancestry cases; 883 European ancestry controls	European(1861)	ALL(1861)	EUR(1861)	ALL(1861)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
18	54754936	rs948651	C	T	rs948651	19010793	1.58E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
18	56213390	rs12456021	G	A	rs12456021	21833088	4.00E-06	NA	1.1	[1.08-1.12]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
18	56384192	rs7238078	T	G	rs7238078	21833088	3.00E-09	NA	1.12	[1.10-1.14]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
18	56384192	rs7238078	T	G	rs7238078	24234648	7.50E-04	NA	1.13	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
18	67531642	rs763361	T	C	rs763361	22190364	1.00E-08	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
18	68908351	rs1376201	A	G	rs1376201	20802204	2.07E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
18	69774278	rs337718	T	C	rs337718	19010793	9.00E-06	NA	NA	NA	794 European ancestry cases; 883 European ancestry controls	European(1677)	ALL(1677)	EUR(1677)	ALL(1677)	Multiple sclerosis (severity)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
18	77148973	rs3859314	A	G	rs3859314	20598377	6.14E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
19	1123378	rs4807569	A	C	rs4807569	22190364	2.12E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
19	6645695	rs454453	C	T	rs454453	17660530	3.90E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
19	6645759	rs390821	A	G	rs390821	17660530	6.14E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
19	6668972	rs1077667	C	T	rs1077667	21833088	9.00E-14	NA	1.16	[1.14-1.18]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
19	10444826	rs2278442	G	A	rs2278442	21833088	1.20E-04	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
19	10520064	rs8112449	G	A	rs8112449	21833088	1.00E-06	NA	1.08	[1.07-1.10]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
19	11682495	rs7253363	T	G	rs7253363	19010793	9.00E-06	NA	NA	NA	794 European ancestry cases; 883 European ancestry controls	European(1677)	ALL(1677)	EUR(1677)	ALL(1677)	Multiple sclerosis (severity)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
19	12146370	rs3745672	T	C	rs3745672	20598377	1.00E-06	NA	7.39	[3.32-16.47]	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
19	13843233	rs346172	T	C	rs346172	17660530	2.23E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
19	16548375	rs10411936	A	G	rs10411936	22190364	2.00E-07	NA	1.16	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
19	17088458	rs12975235	G	A	rs12975235	19010793	1.15E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
19	17111674	rs11669497	T	C	rs11669497	19010793	3.24E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
19	17112827	rs3745341	T	C	rs3745341	19010793	1.02E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
19	17113147	rs3745345	A	G	rs3745345	19010793	2.88E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
19	17118433	rs11666377	C	T	rs11666377	19010793	7.00E-06	NA	NA	NA	791 European ancestry cases; 883 European ancestry controls	European(1674)	ALL(1674)	EUR(1674)	ALL(1674)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
19	17121533	rs6512158	A	C	rs6512158	19010793	9.55E-06	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
19	18304700	rs874628	A	G	rs874628	21833088	1.00E-08	NA	1.11	[1.09-1.12]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
19	30603533	rs8101993	T	C	rs8101993	19010793	7.24E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
19	33750314	rs10500264	G	A	rs10500264	22190364	4.00E-10	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
19	38293963	rs241935	C	A	rs241935	20598377	9.65E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
19	45146103	rs7255066	T	C	rs7255066	21833088	1.00E-06	NA	1.09	[1.07-1.11]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
19	47208481	rs425105	T	C	rs425105	22190364	2.70E-11	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
19	47661493	rs307896	G	A	rs307896	21833088	5.00E-07	NA	1.09	[1.08-1.11]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
19	49214470	rs281380	T	C	rs281380	21833088	2.00E-06	Conditioned on rs2303759	1.08	[1.07-1.09]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
19	49869051	rs2303759	T	G	rs2303759	21833088	5.00E-09	NA	1.11	[1.09-1.13]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
19	56313528	rs299175	G	A	rs299175	19010793	4.00E-06	NA	NA	NA	794 European ancestry cases; 883 European ancestry controls	European(1677)	ALL(1677)	EUR(1677)	ALL(1677)	Multiple sclerosis (severity)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
20	1205886	rs397020	T	C	rs397020	19010793	8.00E-07	NA	1.41	NA	978 European ancestry cases; 883 European ancestry controls	European(1861)	ALL(1861)	EUR(1861)	ALL(1861)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	1304120	rs6041420	T	C	rs6041420	20802204	1.28E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
20	1610551	rs2281808	T	C	rs2281808	22190364	1.20E-11	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	3199703	rs2422862	G	A	rs2422862	19010793	4.90E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
20	3201966	rs2422863	C	T	rs2422863	19010793	3.98E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
20	6671980	rs6038585	A	G	rs6038585	20802204	4.10E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
20	9628822	rs747996	G	C	rs747996	17660530	2.56E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	9644206	rs17408919	C	A	rs17408919	17660530	3.47E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	11955659	rs2223712	G	A	rs2223712	17660530	2.42E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	18325355	rs2424167	A	G	rs2424167	19010793	1.15E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
20	18490913	rs6075351	G	A	rs6075351	19010793	9.33E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
20	19500070	rs636116	A	G	rs636116	17660530	4.27E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	19874222	rs17301932	G	A	rs17301932	17660530	5.05E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	36131085	rs6018946	T	A	rs6018946	17660530	2.46E-04	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	38685541	rs2870137	C	T	rs2870137	19010793	8.13E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
20	40668846	rs41354748	T	C	rs41354748	17660530	6.14E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	43065028	rs6017342	A	C	rs6017342	22190364	9.00E-17	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	44702120	rs2425752	T	C	rs2425752	21833088	5.00E-10	NA	1.11	[1.10-1.13]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	44702120	rs2425752	T	C	rs2425752	24234648	1.00E-04	NA	1.14	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	44724305	rs6131010	A	G	rs6131010	19525955	8.50E-07	NA	NA	NA	1,618 European ancestry cases; 3,413 European ancestry controls	European(5031)	ALL(5031)	EUR(5031)	ALL(5031)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	44740196	rs6074022	C	T	rs6074022	19525955	1.00E-07	NA	1.2	NA	1,618 European ancestry cases; 3,413 European ancestry controls	European(5031)	ALL(5031)	EUR(5031)	ALL(5031)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	44740196	rs6074022	C	T	rs6074022	21833088	2.65E-06	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	44740196	rs6074022	C	T	rs6074022	22190364	5.00E-06	NA	1.15	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	44742064	rs1569723	C	A	rs1569723	19525955	2.90E-07	NA	NA	NA	1,618 European ancestry cases; 3,413 European ancestry controls	European(5031)	ALL(5031)	EUR(5031)	ALL(5031)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	44747947	rs4810485	T	G	rs4810485	22190364	8.20E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	44755111	rs3746821	G	T	rs3746821	17660530	9.71E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	44800445	rs2425764	A	G	rs2425764	17660530	2.34E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	48030010	rs926673	G	T	rs926673	19010793	5.50E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	T
20	48033203	rs237462	C	T	rs237462	19010793	6.76E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
20	48522330	rs495337	G	A	rs495337	22190364	1.00E-08	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	48983697	rs6067417	C	T	rs6067417	20802204	1.51E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
20	50843305	rs2016367	C	G	rs2016367	17660530	3.10E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	52768391	rs2762932	T	C	rs2762932	21833088	8.10E-07	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	52791518	rs2248359	C	T	rs2248359	21833088	3.00E-11	NA	1.12	[1.10-1.13]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	52791518	rs2248359	C	T	rs2248359	24234648	8.50E-04	NA	1.12	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	52841034	rs13039601	A	G	rs13039601	19010793	2.95E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	A
20	52918459	rs1293143	T	C	rs1293143	19010793	1.91E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
20	56402006	rs6025805	C	T	rs6025805	19010793	4.68E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	C
20	59005072	rs348840	A	C	rs348840	20802204	2.65E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
20	62343956	rs2315008	T	G	rs2315008	22190364	9.00E-15	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
20	62409713	rs6062314	C	T	rs6062314	21833088	1.00E-07	NA	1.16	[1.14-1.19]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
21	16805220	rs1736135	T	C	rs1736135	22190364	7.40E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
21	31306654	rs467092	C	T	rs467092	17660530	3.12E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
21	32906992	rs9979653	C	A	rs9979653	20802204	4.61E-06	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
21	32949556	rs2833451	T	C	rs2833451	20802204	1.99E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
21	37907311	rs914148	T	A	rs914148	17660530	1.46E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
21	39871435	rs2836444	T	C	rs2836444	20802204	3.00E-05	NA	NA	NA	372 individuals with multiple sclerosis	NOPOP(372)	ALL(372)	NOPOP(372)	ALL(372)	Multiple sclerosis (brain glutamate levels)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
21	40465534	rs2836878	G	A	rs2836878	22190364	1.40E-08	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
21	41479698	rs451518	C	T	rs451518	23785401	7.82E-04	NA	1.69	NA	49 European ancestry OCB negative cases; 513 European ancestry OCB positive cases	European(562)	ALL(562)	EUR(562)	ALL(562)	Multiple sclerosis (OCB status)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
21	43836390	rs9976767	A	G	rs9976767	22190364	2.00E-08	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
21	45096206	rs2155722	G	A	rs2155722	17660530	7.26E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
21	45119104	rs8129601	T	C	rs8129601	17660530	5.74E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
21	45615561	rs762421	G	A	rs762421	22190364	1.41E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
21	45647421	rs4819388	T	C	rs4819388	22190364	2.46E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
22	22131125	rs2283792	T	G	rs2283792	21833088	5.00E-09	NA	1.1	[1.08-1.11]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
22	22131125	rs2283792	T	G	rs2283792	24234648	3.60E-04	NA	1.12	NA	4,088 Multiple sclerosis cases; 3,762 Amyotrophic lateralsclerosis cases; 12,030 controls	NOPOP(19880)	ALL(19880)	NOPOP(19880)	ALL(19880)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
22	23285252	rs2012607	G	A	rs2012607	19010793	9.12E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Brain lesion load	HPOID:0007319	Morphological abnormality of the central nervous system	DOID:2377	multiple sclerosis	D006429	Hemiplegia	NA	NA	Multiple sclerosis	NA	Multicenter Study	Research Support, Non-U.S. Gov't	G
22	30529631	rs2412973	C	A	rs2412973	22190364	2.00E-09	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
22	30581722	rs5753037	C	T	rs5753037	22190364	2.60E-16	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
22	31169761	rs136319	T	G	rs136319	20598377	6.27E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
22	33121988	rs9621545	C	G	rs9621545	19525953	4.44E-05	NA	NA	NA	2,624 cases; 7,220 controls	NOPOP(9844)	ALL(9844)	NOPOP(9844)	ALL(9844)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
22	37268555	rs2072711	A	G	rs2072711	21833088	6.30E-05	NA	NA	NA	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
22	37551607	rs743777	A	G	rs743777	22190364	3.00E-10	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
22	37591318	rs229541	G	A	rs229541	22190364	2.00E-08	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
22	42339516	rs3752591	A	G	rs3752591	20598377	8.13E-05	NA	NA	NA	590 Caucasian European descent cases; 825 Caucasian European descent controls	Caucasian European(1415)	ALL(1415)	EUR(1415)	ALL(1415)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
22	48318132	rs874960	A	G	rs874960	17660530	9.47E-06	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
22	49446381	rs17000271	T	C	rs17000271	17660530	2.06E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
22	50435480	rs5771069	A	G	rs5771069	22190364	4.00E-08	NA	NA	NA	5,545 European ancestry cases; 12,153 European ancestry controls	European(17698)	ALL(17698)	EUR(17698)	ALL(17698)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
22	50971266	rs140522	T	C	rs140522	21833088	2.00E-08	NA	1.1	[1.09-1.12]	9,772 European ancestry cases; 16,849 European ancestry controls	European(26621)	ALL(26621)	EUR(26621)	ALL(26621)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
X	13615118	rs5978649	A	G	rs5978649	23412934	4.00E-06	Cluxel minimum distance	NA	NA	284 European ancestry individuals	European(284)	ALL(284)	EUR(284)	ALL(284)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
X	23322621	rs886546	C	A	rs886546	19010793	3.80E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
X	27830391	rs5926910	A	G	rs5926910	17660530	3.31E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
X	27839572	rs1368769	T	C	rs1368769	17660530	5.63E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
X	34892503	rs4271113	G	A	rs4271113	23412934	9.00E-07	Cluxel minimum distance	NA	NA	284 European ancestry individuals	European(284)	ALL(284)	EUR(284)	ALL(284)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861
X	41412729	rs5918201	T	C	rs5918201	19010793	2.57E-05	NA	NA	NA	753 cases; 883 controls	NOPOP(1636)	ALL(1636)	NOPOP(1636)	ALL(1636)	Multiple sclerosis (age of onset)	HPOID:0000096	HPOID:0001967	HPOID:0100861	HPOID:0004030	HPOID:0002694	HPOID:0005652	HPOID:0009741	HPOID:0008664	HPOID:0005686	HPOID:0004979	HPOID:0100899	HPOID:0002634	HPOID:0003881
X	85072282	rs12008641	A	C	rs12008641	17660530	5.71E-05	NA	NA	NA	931 trios; 2,431 controls	NOPOP(3362)	ALL(3362)	NOPOP(3362)	ALL(3362)	Multiple sclerosis	HPOID:0000096	HPOID:0001967	HPOID:0009741	HPOID:0008664	HPOID:0001150	HPOID:0005450	HPOID:0005652	HPOID:0005686	HPOID:0005789	HPOID:0100923	HPOID:0100925	HPOID:0006623	HPOID:0100861

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:6)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0026769	baclofen	D001418	1134-47-0	multiple sclerosis	MESH:D009103	therapeutic	9711203
C0026769	cladribine	D017338	4291-63-8	multiple sclerosis	MESH:D009103	therapeutic	12898844
C0026769	glatiramer acetate	D000068717	-	multiple sclerosis	MESH:D009103	therapeutic	12432978
C0026769	dextromethorphan	D003915	125-71-3	multiple sclerosis	MESH:D009103	therapeutic	16634036
C0026769	mitoxantrone	D008942	65271-80-9	multiple sclerosis	MESH:D009103	therapeutic	12297576
C0026769	nitric oxide	D009569	10102-43-9	multiple sclerosis	MESH:D009103	marker/mechanism	17437305

FDA approved drug and dosage information(Total Drugs:1)
DiseaseID	Drug_name	active_ingredients	strength	Dosage Form/Route	Marketing Status	TE code	RLD	RS
MESH:D009103	inomax	nitric oxide	100PPM Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons	GAS;INHALATION	Discontinued	None	Yes	No

FDA labeling changes(Total Drugs:1)
DiseaseID	Pediatric_Labeling_Date	Trade_Name	Generic_Name_or_Proper_Name	Indications Studied	Label Changes Summary	Product Labeling	BPCA(B)	PREA(P)	BPCA(B) and PREA(P)	Pediatric Rule (R)	Sponsor	Pediatric Exclusivity Granted Date	NNPS
MESH:D009103	12/21/2010	inomax	nitric oxide	Prevention of bronchopulmonary dysplasia	INOmax is not indicated for prevention of BPD in preterm neonates d 34 weeks gestational age.Efficacy for the prevention of BPD in preterm infants was not established in three ldouble-blind, placebo-controlled clinical trials in a total of 2,149 preterm infants Information on clinical trials, adverse reaction	Labeling	B	-	-	-	INO Therapeutics	2/11/2010	FALSE'